accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P56892 | CYSD_RHIME | Sulfate adenylate transferase | Sinorhizobium | <M><P><H><T><L><P><E><T><E><L><H><N><P><Q><S><T><K><P><P><L><D><P><H><L><K><A><L><E><N><E><A><I><H><I><F><R><E><V><A><A><E><F><E><R><P><V><M><L><Y><S><I><G><K><D><S><S><V><L><L><H><L><A><R><K><A><F><Y><P><G><R><I><P><F><P><L><L><H><V><D><T><G><W><K><F><R><E><M><I><A><F><R><D><E><M><V><A><K><Y><D><L><D><L><V><A><H><T><N... | With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi... | P56892 |
B7USC8 | ASTA_ECO27 | AOST | Escherichia | <M><M><V><I><R><P><V><E><R><S><D><V><S><A><L><M><Q><L><A><S><K><T><G><G><G><L><T><S><L><P><A><N><E><A><T><L><S><V><R><I><E><R><A><I><K><T><W><Q><G><E><L><P><K><S><E><Q><G><Y><V><F><V><L><E><D><S><E><T><G><T><V><A><G><I><C><A><I><E><V><A><V><G><L><N><D><P><W><Y><N><Y><R><V><G><T><L><V><H><A><S><K><E><L><N><V><Y><N><A><L... | Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.<BOP> | B7USC8 |
P30516 | 1B01_SAGOE | Class I histocompatibility antigen, B alpha chain | Saguinus | <M><T><V><M><A><P><R><T><L><L><L><L><L><S><G><A><L><V><L><T><E><T><W><A><G><S><H><S><M><R><Y><F><S><T><A><V><S><R><P><G><R><E><E><P><R><Y><I><E><V><G><Y><V><D><D><T><Q><F><V><R><F><D><S><D><A><A><S><P><R><M><E><P><R><A><Q><W><V><E><K><E><G><R><E><Y><W><E><E><E><T><Q><R><A><K><A><F><A><Q><T><F><R><V><N><L><Q><T><A><L><G... | Involved in the presentation of foreign antigens to the immune system.<BOP> | P30516 |
Q74IS9 | RBFA_LACJO | Ribosome-binding factor A | Lactobacillus | <M><K><H><R><I><G><R><V><E><G><E><I><L><R><E><L><T><K><I><L><R><K><D><I><R><D><P><R><L><N><D><V><T><I><T><A><V><E><C><T><N><D><L><S><Y><A><T><V><Y><Y><S><M><L><T><D><D><P><A><K><E><K><E><V><A><E><G><L><D><K><A><K><G><M><M><R><H><L><L><G><Q><T><L><T><V><Y><K><V><P><E><L><I><F><K><R><D><T><S><V><A><Y><G><S><K><I><D><K><L... | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | Q74IS9 |
Q7NFA4 | ISPG_GLOVI | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase | Gloeobacter | <M><Q><T><L><D><P><V><T><P><A><L><L><P><L><R><R><V><T><R><P><V><Q><V><G><A><L><T><I><G><G><N><A><P><V><V><V><Q><S><M><I><N><E><D><T><L><D><T><P><G><A><V><A><A><I><R><A><L><H><K><A><G><C><E><L><V><R><V><T><V><P><S><L><A><H><A><R><A><L><E><R><I><R><K><T><L><E><D><T><Y><R><P><V><P><L><V><A><D><V><H><H><D><G><G><P><I><A><L... | Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.<BOP> | Q7NFA4 |
P46278 | CCNB2_MEDSV | CycMs2 | Medicago | <M><V><N><T><S><E><E><N><N><S><N><A><V><M><P><R><K><F><Q><G><G><M><N><Q><V><G><H><G><G><G><R><I><V><G><Q><N><R><R><A><L><G><G><I><N><Q><N><F><V><H><G><R><P><Y><P><C><V><V><H><K><R><V><L><S><E><K><H><E><I><C><E><K><K><Q><A><D><L><G><H><R><P><I><T><R><R><F><A><A><K><I><A><G><S><Q><Q><S><Y><A><E><K><T><K><N><S><N><P><L><N... | Essential for the control of the cell cycle at the G2/M (mitosis) transition.<BOP> | P46278 |
P19112 | F16P1_RAT | Liver FBPase | Rattus | <M><V><D><H><A><P><F><E><T><D><I><S><T><L><T><R><F><V><L><E><E><G><R><K><A><G><G><T><G><E><M><T><Q><L><L><N><S><L><C><T><A><I><K><A><I><S><S><A><V><R><Q><A><G><I><A><Q><L><Y><G><I><A><G><S><T><N><V><T><G><D><Q><V><K><K><L><D><I><L><S><N><D><L><V><I><N><M><L><K><S><S><Y><A><T><C><V><L><V><S><E><E><D><T><H><A><I><I><I><E... | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Import... | P19112 |
P52201 | PUR8_SPICI | Adenylosuccinase | Spiroplasma | <M><I><E><R><Y><F><V><T><E><I><G><K><I><W><S><D><E><N><K><Y><N><T><W><A><K><V><E><L><L><V><C><E><G><W><A><Q><I><G><L><I><P><P><T><D><I><E><K><I><K><T><N><L><T><V><N><L><P><R><M><L><E><L><E><A><E><T><K><H><D><V><V><A><F><T><R><M><L><S><E><T><L><G><P><E><K><K><W><I> | Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)... | P52201 |
A3NX99 | HUTI_BURP0 | Imidazolone-5-propionate hydrolase | pseudomallei group | <M><K><S><I><L><W><H><N><L><K><L><C><A><H><G><D><P><N><D><T><I><A><D><A><A><I><A><V><N><G><D><G><T><I><A><W><T><G><R><A><S><D><V><P><A><G><Y><V><H><W><P><R><E><D><L><R><G><A><W><V><T><P><G><L><V><D><C><H><T><H><L><V><Y><G><G><Q><R><A><D><E><F><A><Q><R><L><A><G><A><S><Y><E><E><I><A><Q><R><G><G><G><I><V><S><T><V><R><A><T... | Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.<BOP> | A3NX99 |
Q6CZT2 | PLY3_PECAS | Pectate lyase III | Pectobacterium | <M><K><Y><L><L><P><S><T><A><A><G><L><L><L><L><A><A><Q><P><T><M><A><A><N><T><G><G><Y><A><T><T><D><G><G><N><V><A><G><A><V><N><K><T><A><R><S><M><Q><D><I><I><D><I><I><E><E><A><K><L><D><S><K><G><K><K><V><K><G><G><A><Y><P><L><I><I><T><Y><N><G><N><E><D><A><L><I><K><A><A><E><N><N><I><C><G><Q><W><S><K><D><A><R><G><V><E><I><K><E... | Involved in maceration and soft-rotting of plant tissue.<BOP> | Q6CZT2 |
Q1QUF9 | CYSN_CHRSD | Sulfate adenylate transferase | Chromohalobacter | <M><S><H><Q><S><S><L><I><A><E><D><I><E><S><Y><L><Q><E><H><E><Q><K><D><L><L><R><F><I><T><C><G><S><V><D><D><G><K><S><T><L><I><G><R><L><L><H><D><S><K><M><I><Y><E><D><Q><L><A><A><I><T><Q><A><S><R><T><S><G><T><T><G><D><Q><V><D><L><A><L><L><V><D><G><L><Q><S><E><R><E><Q><G><I><T><I><D><V><A><Y><R><Y><F><S><T><D><K><R><K><F><I... | With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi... | Q1QUF9 |
C4Z2R3 | RL7_LACE2 | 50S ribosomal protein L7/L12 | Lachnospira | <M><T><T><Q><E><I><I><E><V><I><K><G><L><S><V><L><E><L><N><D><L><V><K><A><C><E><E><E><F><G><V><S><A><A><A><G><V><V><V><A><A><A><G><A><G><A><A><A><A><E><E><K><T><E><F><D><V><E><L><T><E><A><G><D><Q><K><V><K><V><I><K><V><V><R><E><I><T><G><L><G><L><K><E><A><K><D><V><V><D><G><A><P><K><V><V><K><E><Q><A><S><K><E><E><A><E><E><I... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP> | C4Z2R3 |
Q34653 | CYB_ANTRB | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Antigone | <M><A><P><N><L><R><K><S><H><P><L><L><K><M><I><N><N><S><L><I><D><L><P><T><P><S><N><I><S><A><W><W><N><F><G><S><L><L><G><I><C><L><A><T><Q><I><L><T><G><L><L><L><A><A><H><Y><T><A><D><T><T><L><A><F><S><S><V><A><H><T><C><R><N><V><Q><H><G><W><L><I><R><N><L><H><A><N><G><A><S><F><F><F><I><C><I><Y><L><H><I><G><R><G><L><Y><Y><G><S... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q34653 |
Q3JCW1 | DER_NITOC | GTP-binding protein EngA | Nitrosococcus | <M><N><A><L><V><A><L><V><G><R><P><N><V><G><K><S><T><L><F><N><R><L><T><R><S><R><D><A><L><V><V><D><Q><P><G><V><T><R><D><R><K><Y><G><L><A><H><Y><G><E><Q><S><F><F><V><V><D><T><G><G><V><M><E><Q><E><S><G><I><G><R><L><M><R><A><Q><A><Q><L><A><I><E><E><A><D><V><I><F><F><L><V><D><G><R><E><G><L><S><S><L><D><E><E><I><A><A><W><L><R... | GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP> | Q3JCW1 |
B8E6W2 | NRDR_SHEB2 | Transcriptional repressor NrdR | Shewanella | <M><H><C><P><F><C><S><A><T><D><T><K><V><I><D><S><R><L><V><A><E><G><H><Q><V><R><R><R><R><E><C><T><E><C><H><E><R><F><T><T><F><E><G><A><E><L><V><M><P><R><V><I><K><R><D><G><S><R><Q><P><F><D><E><E><K><L><Q><G><G><M><L><R><A><V><E><K><R><P><V><S><M><D><E><I><E><Q><A><L><S><K><I><K><S><T><L><R><A><T><G><E><R><E><V><P><S><E><M... | Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP> | B8E6W2 |
Q5E305 | SDHE_ALIF1 | FAD assembly factor SdhE | Aliivibrio | <M><Y><S><A><E><E><K><A><R><V><K><W><A><C><R><R><G><M><L><E><L><D><V><V><I><M><P><F><F><D><E><C><F><E><E><L><T><E><A><E><Q><Q><A><F><V><S><L><L><E><C><D><D><P><D><L><F><T><W><V><M><G><H><G><R><S><D><N><L><A><H><A><S><M><V><D><K><I><V><E><H><N><L><S><K><L><R> | An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which cou... | Q5E305 |
A0Q5M5 | SYS_FRATN | Seryl-tRNA(Ser/Sec) synthetase | Francisella | <M><L><D><A><K><Y><I><K><D><N><L><Q><Q><V><A><E><K><L><A><T><R><G><Y><Q><F><D><I><A><E><F><E><A><Q><E><Q><K><R><R><H><L><Q><E><R><T><Q><D><L><Q><S><Q><R><N><T><I><S><K><E><I><G><Q><K><K><A><K><G><E><D><T><S><D><I><F><A><K><V><N><Q><I><N><E><E><L><K><I><I><E><K><E><L><K><D><L><Q><D><T><I><N><Q><T><L><L><S><M><P><N><L><P... | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP> | A0Q5M5 |
Q8Z327 | RSD_SALTI | Regulator of sigma D | Salmonella | <M><L><N><Q><L><E><N><L><M><E><R><V><G><G><S><N><K><L><V><D><R><W><L><D><V><R><K><H><L><L><V><A><Y><Y><N><L><V><G><I><K><P><G><K><E><S><Y><M><R><L><N><E><K><A><L><D><D><F><C><Q><S><L><V><D><Y><L><S><A><G><H><F><S><I><Y><E><R><I><L><H><K><L><E><G><N><G><Q><L><L><H><A><A><K><I><W><P><L><L><E><D><N><T><Q><R><I><M><D><Y><Y... | Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition f... | Q8Z327 |
A7H2A2 | TRMB_CAMJD | tRNA(m7G46)-methyltransferase | Campylobacter | <M><P><N><F><K><S><K><K><I><K><E><I><N><L><P><Y><S><K><D><D><V><E><F><L><W><F><A><K><N><D><N><V><S><L><I><Y><T><K><V><Q><E><E><S><F><F><L><Q><I><K><K><A><Q><N><G><F><V><I><K><G><D><K><H><T><K><P><S><K><I><G><Y><L><Q><K><A><L><K><I><F><K><E><G><F><C><E><D><I><I><N><E><A><F><G><L><K><N><N><A><L><I><E><K><T><P><F><I><V><D... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | A7H2A2 |
P01709 | LV208_HUMAN | Ig lambda chain V-II region MGC | Homo | <M><A><W><A><L><L><L><L><T><L><L><T><Q><G><T><G><S><W><A><Q><S><A><L><T><Q><P><P><S><A><S><G><S><P><G><Q><S><V><T><I><S><C><T><G><T><S><S><D><V><G><G><Y><N><Y><V><S><W><Y><Q><Q><H><P><G><K><A><P><K><L><M><I><Y><E><V><S><K><R><P><S><G><V><P><D><R><F><S><G><S><K><S><G><N><T><A><S><L><T><V><S><G><L><Q><A><E><D><E><A><D><Y... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01709 |
Q8KHS0 | REBO_LENAE | L-amino acid oxidase protein | Lentzea | <M><S><R><G><H><K><K><I><T><V><L><G><A><G><V><A><G><L><V><A><A><H><E><L><E><E><L><G><H><E><V><E><V><L><E><G><S><D><R><L><G><G><R><V><H><T><H><R><F><G><E><G><G><S><V><P><F><V><E><L><G><A><M><R><I><P><T><K><H><R><H><T><I><D><Y><I><G><K><L><G><L><T><P><K><L><K><E><F><K><T><L><F><S><D><D><G><A><Y><H><T><T><S><A><G><F><V><R... | Involved in the biosynthesis of the indolocarbazole antitumor agent rebeccamycin. It generates the imine form of 7-chloroindole 3-pyruvate (7Cl-IPA) from 7-chloro-L-tryptophan (7Cl-Trp), with concomitant two-electron reduction of O(2) to H(2)O(2). The enzyme is also active with L-tryptophan as substrate.<BOP> | Q8KHS0 |
Q82FB5 | AZOR_STRAW | FMN-dependent NADH-azoreductase | Streptomyces | <M><A><T><L><L><H><I><D><S><S><V><F><P><S><A><A><S><A><S><R><A><V><A><E><T><F><R><T><A><W><Q><E><Q><H><P><D><G><T><V><I><Y><R><D><L><S><A><N><P><V><P><H><I><T><A><D><A><H><T><A><G><F><A><D><P><A><T><H><T><P><G><Q><A><A><A><F><A><E><R><E><K><L><I><A><E><L><E><Q><A><D><A><V><L><I><G><A><P><M><Y><N><Y><A><I><P><S><T><L><K... | Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.<BOP> | Q82FB5 |
Q7SFC8 | ROK1_NEUCR | DEAD box RNA helicase 16 | Neurospora | <M><D><I><F><K><V><L><S><R><G><I><K><A><Q><P><K><K><N><Q><P><G><A><P><Q><L><L><P><S><A><G><A><K><V><N><P><Q><F><F><H><D><N><V><G><G><A><N><A><K><R><G><K><K><R><K><R><K><G><A><Q><A><N><N><A><T><E><S><G><D><E><D><D><D><A><S><D><V><D><Y><F><A><P><K><P><T><P><E><E><L><A><A><K><K><D><A><E><L><K><A><D><E><P><K><K><Q><K><P><K... | ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.<BOP> | Q7SFC8 |
Q9JK30 | ORC3_MOUSE | Origin recognition complex subunit Latheo | Mus | <M><H><T><G><P><R><T><M><A><T><S><S><V><S><K><G><C><F><V><F><K><P><D><F><K><K><R><K><V><F><V><P><I><E><D><Y><F><N><N><E><E><L><D><S><E><D><S><K><L><R><F><E><T><Y><S><L><L><W><Q><R><M><K><S><E><T><E><Q><L><Q><E><E><L><N><E><N><L><F><D><N><L><V><D><F><L><Q><K><S><H><P><E><F><Q><K><N><S><R><D><W><G><S><Q><M><K><F><R><E><I... | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 a... | Q9JK30 |
B4LUF5 | NUBP1_DROVI | Cytosolic Fe-S cluster assembly factor NUBP1 homolog | Drosophila | <M><Q><A><P><P><P><E><H><C><P><G><V><E><S><E><Q><A><G><L><V><S><A><C><A><G><C><P><N><Q><S><I><C><S><D><P><S><K><K><L><E><D><P><G><K><A><L><V><A><A><A><M><K><D><V><K><H><K><L><L><I><L><S><G><K><G><G><V><G><K><S><T><V><T><T><L><L><T><R><Y><L><A><R><S><Y><P><D><N><N><F><G><V><L><D><I><D><I><C><G><P><S><Q><P><R><L><L><G><A... | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.<BOP> | B4LUF5 |
C3LPC8 | HEM6_VIBCM | Oxygen-dependent coproporphyrinogen-III oxidase | Vibrio | <M><K><S><N><I><D><K><Q><A><V><K><N><F><L><L><Q><L><Q><D><Q><I><C><Q><Q><L><E><A><A><D><G><Q><A><Q><F><I><E><D><A><W><Q><R><E><P><G><E><K><L><G><G><G><G><R><T><R><V><M><R><D><G><A><V><F><E><Q><G><G><V><N><F><S><H><V><F><G><E><Q><M><P><G><S><A><T><A><H><R><P><E><L><A><G><R><R><F><E><A><M><G><V><S><L><V><M><H><P><K><N><P... | Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.<BOP> | C3LPC8 |
A1JSF8 | BIOH_YERE8 | Carboxylesterase BioH | Yersinia | <M><K><Q><L><Y><W><N><I><C><G><E><G><D><C><D><L><V><L><L><H><G><W><G><L><N><A><G><V><W><H><C><I><I><D><R><L><T><P><H><F><R><L><H><L><V><D><L><P><G><Y><G><R><S><T><E><F><G><A><M><S><L><S><E><M><A><E><I><V><L><Q><Q><A><P><Q><Q><A><I><W><L><G><W><S><M><G><G><L><V><A><S><Q><I><A><L><S><H><P><E><R><V><R><G><L><I><T><V><S><S... | The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.<BOP> | A1JSF8 |
B6HDM7 | MMM1_PENRW | Maintenance of mitochondrial morphology protein 1 | Penicillium chrysogenum species complex | <M><A><L><Q><Q><H><E><P><A><P><F><A><P><Q><S><S><L><S><F><T><Q><G><F><L><L><G><Q><L><S><V><V><L><L><I><G><A><F><I><K><F><F><I><F><G><E><A><P><P><P><P><S><R><G><M><S><N><R><T><T><H><R><R><Y><S><S><V><Y><S><P><P><Q><D><S><Q><K><S><L><R><E><K><P><S><T><S><N><V><L><R><P><V><P><S><T><S><T><N><T><R><S><I><L><R><K><T><Y><Y><S... | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm... | B6HDM7 |
B7NEG2 | TREF_ECOLU | Alpha,alpha-trehalose glucohydrolase | Escherichia | <M><L><N><Q><K><I><Q><N><P><N><P><D><E><L><M><I><E><V><D><L><C><Y><E><L><D><P><Y><E><L><K><L><D><E><M><I><E><A><E><P><E><P><E><M><I><E><G><L><P><A><S><D><A><L><T><P><A><D><R><Y><L><E><L><F><E><H><V><Q><S><A><K><I><F><P><D><S><K><T><F><P><D><C><A><P><K><M><D><P><L><D><I><L><I><R><Y><R><K><V><R><R><H><R><D><F><D><L><R><K... | Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.<BOP> | B7NEG2 |
Q5LIJ0 | RSMH_BACFN | rRNA (cytosine-N(4)-)-methyltransferase RsmH | Bacteroides | <M><K><E><E><E><T><T><Y><H><V><P><V><L><L><K><E><S><V><D><A><M><N><I><S><P><D><G><T><Y><V><D><V><T><F><G><G><G><G><H><S><R><E><I><L><S><R><L><G><D><G><G><R><L><L><G><F><D><Q><D><E><D><A><E><R><N><I><V><N><D><P><H><F><T><F><V><R><S><N><F><R><Y><L><H><N><F><L><R><Y><H><D><I><G><E><V><D><A><I><L><A><D><L><G><V><S><S><H><H... | Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP> | Q5LIJ0 |
Q975D6 | CDC62_SULTO | ORC1-type DNA replication protein 2 | Sulfurisphaera | <M><K><V><L><D><E><L><R><D><L><V><E><D><A><I><K><G><S><T><V><F><E><K><S><K><V><L><T><P><D><Y><I><P><K><N><L><P><H><R><E><K><Q><I><K><E><L><S><I><N><F><R><E><I><L><S><N><P><G><S><T><S><V><R><V><V><I><S><G><K><T><G><T><G><K><T><V><T><T><K><K><F><G><E><L><F><S><E><I><A><K><E><K><G><L><R><V><V><Y><T><H><I><N><C><H><R><Q><R... | Involved in regulation of DNA replication.<BOP> | Q975D6 |
P47932 | REL1_MOUSE | Relaxin A chain | Mus | <M><S><S><R><F><L><L><Q><L><L><G><F><W><L><L><L><S><Q><P><C><R><T><R><V><S><E><E><W><M><D><G><F><I><R><M><C><G><R><E><Y><A><R><E><L><I><K><I><C><G><A><S><V><G><R><L><A><L><S><Q><E><E><P><A><L><L><A><R><Q><A><T><E><V><V><P><S><F><I><N><K><D><A><E><P><F><D><T><T><L><K><C><L><P><N><L><S><E><E><L><K><A><V><L><S><E><A><Q><A... | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.<BOP> | P47932 |
B0T2C2 | RL3_CAUSK | 50S ribosomal protein L3 | unclassified Caulobacter | <M><T><L><P><A><N><R><T><G><V><I><A><K><K><L><G><M><T><R><F><F><D><E><T><G><Q><H><V><P><V><T><V><L><S><L><D><G><C><Q><V><T><A><Q><R><T><V><E><K><D><G><Y><T><A><L><Q><L><G><A><G><A><K><K><P><K><N><T><P><N><A><M><R><G><H><F><A><K><N><S><V><E><P><K><R><I><V><A><E><F><R><V><D><E><A><A><L><I><E><V><G><A><E><F><T><A><D><H><Y... | One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP> | B0T2C2 |
Q92A25 | LEUD_LISIN | Isopropylmalate isomerase | Listeria | <M><E><A><I><K><V><H><I><G><K><T><V><A><L><M><N><D><N><I><D><T><D><Q><I><I><P><K><S><F><L><K><R><I><E><R><T><G><F><G><E><F><L><F><D><S><W><R><Y><L><P><N><R><K><P><N><P><D><F><P><L><N><A><P><D><R><Q><E><A><T><I><L><I><T><G><D><N><F><G><C><G><S><S><R><E><H><A><A><W><A><L><L><D><Y><R><F><R><V><I><I><A><G><S><Y><S><D><I><F... | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP> | Q92A25 |
Q72JE9 | DEOC_THET2 | Phosphodeoxyriboaldolase | Thermus | <M><D><L><A><A><H><I><D><H><T><L><L><K><P><T><A><T><P><E><E><V><A><K><A><A><E><E><A><L><E><Y><G><F><Y><G><L><C><I><P><P><S><Y><V><A><W><V><K><A><R><Y><P><H><A><P><F><R><L><V><T><V><V><G><F><P><L><G><Y><Q><E><K><E><V><K><A><L><E><A><A><L><A><C><A><R><G><A><D><E><V><D><M><V><L><H><L><G><R><A><K><A><G><D><L><D><Y><V><E><A... | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<BOP> | Q72JE9 |
C5D4U8 | GPR_GEOSW | Spore protease | unclassified Geobacillus | <M><N><R><S><I><D><L><S><M><Y><S><V><R><T><D><L><A><I><E><A><H><E><I><A><V><E><E><R><L><Q><Q><K><R><E><S><A><S><P><I><E><G><V><I><I><H><D><R><E><I><D><G><I><K><L><S><H><V><E><V><T><E><E><G><A><K><S><I><G><K><K><P><G><N><Y><L><T><I><E><A><Q><G><I><R><E><H><N><T><E><L><Q><Q><K><V><Q><D><I><F><A><K><E><F><N><A><F><L><R><K... | Initiates the rapid degradation of small, acid-soluble proteins during spore germination.<BOP> | C5D4U8 |
Q61056 | TRPC1_MOUSE | Trp-related protein 1 | Mus | <M><M><A><A><L><Y><P><S><T><D><L><S><G><V><S><S><S><S><L><P><S><S><P><S><S><S><S><P><N><E><V><M><A><L><K><D><V><R><E><V><K><E><E><N><T><L><N><E><K><L><F><L><L><A><C><D><K><G><D><Y><Y><M><V><K><K><I><L><E><E><N><S><S><G><D><L><N><I><N><C><V><D><V><L><G><R><N><A><V><T><I><T><I><E><N><E><S><L><D><I><L><Q><L><L><L><D><Y><G... | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.<BOP> | Q61056 |
Q216Q6 | RPIA_RHOPB | Phosphoriboisomerase A | Rhodopseudomonas | <M><S><S><D><E><L><K><R><Q><A><A><A><A><A><L><E><H><V><R><D><G><M><K><L><G><L><G><T><G><S><T><A><K><H><F><V><E><L><L><G><E><R><V><R><G><G><L><N><V><V><G><V><P><T><S><E><V><T><R><A><D><A><L><R><C><G><I><A><L><T><T><L><D><E><V><D><R><L><D><L><T><V><D><G><A><D><E><I><N><A><A><L><N><L><I><K><G><G><G><G><A><L><L><R><E><K><I... | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP> | Q216Q6 |
B1YL74 | RECO_EXIS2 | Recombination protein O | Exiguobacterium | <M><I><D><K><A><E><G><L><V><L><R><T><V><V><Y><G><E><S><N><K><I><I><T><L><L><T><R><E><Y><G><K><L><A><V><M><A><R><G><A><K><K><P><G><S><R><F><N><A><A><S><Q><P><F><V><R><A><I><Y><V><Y><P><R><S><R><G><L><G><Q><L><K><S><A><D><V><I><T><G><Y><S><K><I><R><Q><D><V><F><L><M><A><Y><A><M><Y><L><L><E><L><A><D><K><A><L><D><E><R><V><P... | Involved in DNA repair and RecF pathway recombination.<BOP> | B1YL74 |
Q812Y1 | MURG3_BACCR | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 3 | Bacillus cereus group | <M><S><K><T><I><L><F><T><G><G><G><T><A><G><H><V><M><I><N><I><V><L><I><P><K><F><I><E><K><G><W><R><V><E><Y><I><G><S><K><N><G><I><E><K><S><L><V><Q><N><V><K><Y><N><S><V><S><T><G><K><L><R><R><Y><W><D><W><D><N><F><K><D><P><F><K><I><I><R><G><C><L><Q><S><Y><N><L><I><K><K><T><K><P><D><V><I><F><S><A><G><G><F><V><S><V><P><V><A><I... | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).<BOP> | Q812Y1 |
Q99V46 | SSPB_STAAM | Staphylopain B | Staphylococcus | <M><N><S><S><Y><K><S><R><V><F><N><I><I><S><I><I><M><V><S><M><L><I><L><S><L><G><A><F><A><N><N><N><K><A><K><A><D><S><H><S><K><Q><L><E><I><N><V><K><S><D><K><V><P><Q><K><V><K><D><L><A><Q><Q><Q><F><A><G><Y><A><K><A><L><D><K><Q><S><N><A><K><T><G><K><Y><E><L><G><E><A><F><K><I><Y><K><F><N><G><E><E><D><N><S><Y><Y><Y><P><V><I><K... | Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S.aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expres... | Q99V46 |
Q01QM3 | DXR_SOLUE | 2-C-methyl-D-erythritol 4-phosphate synthase | Candidatus Solibacter | <M><K><T><I><A><V><L><G><S><T><G><S><I><G><T><N><T><L><D><V><V><R><R><N><R><H><L><Y><E><V><Y><S><L><V><A><G><Q><N><I><E><L><L><T><G><Q><I><L><E><F><R><P><K><L><A><V><V><A><S><A><A><V><L><D><L><L><T><A><S><L><Q><A><A><G><L><P><K><S><E><W><P><D><L><L><S><G><D><A><A><R><V><A><A><V><R><A><P><E><V><D><T><V><I><S><A><I><V><G... | Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP> | Q01QM3 |
S3D9F1 | GLOL_GLAL2 | Pneumocandin biosynthesis cluster protein L | Glarea | <M><G><D><I><S><G><S><V><D><P><S><N><M><A><Y><E><P><L><A><I><V><G><M><G><M><R><L><P><G><G><I><H><T><A><E><D><F><W><N><L><L><V><E><K><R><S><S><R><C><K><V><P><S><D><R><F><N><I><E><A><F><Y><S><P><S><G><R><V><G><T><V><K><M><E><H><G><H><F><L><G><P><T><D><D><L><Q><H><F><D><A><S><F><F><S><M><S><K><K><E><V><E><I><L><D><P><Q><Q... | Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non-competitive inhibition of beta-1,3-glucan synthase . The 10,12-dimethylmyristoyl side chain is synthesized by the redu... | S3D9F1 |
O83149 | RP54_TREPA | RNA polymerase sigma-54 factor | Treponema | <M><Q><Q><L><V><Q><Q><Q><R><L><V><L><N><Q><R><L><V><H><G><L><C><L><L><Q><L><S><R><G><D><L><K><T><E><V><L><R><A><V><Q><R><N><P><L><L><E><I><R><P><S><S><A><R><R><T><G><K><A><C><Y><L><S><L><G><D><R><R><E><R><M><R><A><R><D><R><F><Q><Q><L><L><E><N><Q><P><D><K><Q><V><D><N><I><R><A><V><L><R><E><Q><V><F><Y><Q><K><H><E><A><I><V... | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.<BOP> | O83149 |
Q7VGE1 | RL2_HELHP | 50S ribosomal protein L2 | Helicobacter | <M><A><V><K><T><Y><K><P><Y><T><P><S><R><R><F><M><S><N><L><S><S><S><D><I><T><G><K><A><S><V><K><S><L><L><I><K><L><P><V><S><A><G><R><N><N><N><G><R><I><T><S><R><H><K><E><G><G><A><K><K><F><Y><R><I><I><D><F><K><R><N><K><F><N><I><Q><G><K><V><A><A><I><E><Y><D><P><Y><R><N><C><R><I><A><L><I><H><Y><V><D><G><E><K><R><Y><I><I><Q><P... | One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<... | Q7VGE1 |
Q7N5M6 | FLGI_PHOLL | Basal body P-ring protein | Photorhabdus | <M><I><K><Q><F><A><V><S><L><L><L><V><L><L><T><L><V><T><T><T><A><S><A><E><R><I><R><D><L><T><T><V><Q><G><V><R><E><N><A><L><I><G><Y><G><L><V><V><G><L><D><G><T><G><D><Q><T><T><Q><T><P><F><T><T><Q><S><L><S><N><M><L><S><Q><L><G><I><T><V><P><P><G><T><N><M><Q><L><K><N><V><A><A><V><M><V><T><A><K><L><P><P><F><G><R><A><G><Q><N><I... | Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.<BOP> | Q7N5M6 |
A0B796 | RNH2_METTP | Ribonuclease HII | Methanothrix | <M><M><L><I><L><G><V><D><E><A><G><K><G><P><V><I><G><S><M><F><V><A><G><V><V><F><S><E><E><D><I><F><D><L><A><A><C><G><V><K><D><S><K><L><L><S><P><T><R><R><E><S><M><E><R><K><I><L><S><I><A><R><E><S><F><V><L><E><V><T><A><Q><Q><I><D><D><L><R><M><V><M><S><M><N><E><I><M><V><R><A><H><S><R><V><V><S><R><L><Q><A><D><R><A><I><L><D><A... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | A0B796 |
Q9BQS7 | HEPH_HUMAN | Hephaestin | Homo | <M><E><S><G><H><L><L><W><A><L><L><F><M><Q><S><L><W><P><Q><L><T><D><G><A><T><R><V><Y><Y><L><G><I><R><D><V><Q><W><N><Y><A><P><K><G><R><N><V><I><T><N><Q><P><L><D><S><D><I><V><A><S><S><F><L><K><S><D><K><N><R><I><G><G><T><Y><K><K><T><I><Y><K><E><Y><K><D><D><S><Y><T><D><E><V><A><Q><P><A><W><L><G><F><L><G><P><V><L><Q><A><E><V... | May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1.<BOP> | Q9BQS7 |
A1K991 | SYA_AZOSB | Alanyl-tRNA synthetase | Azoarcus | <M><K><S><A><E><I><R><A><K><F><L><K><F><F><E><S><K><G><H><Q><I><V><A><S><S><S><L><V><P><H><E><D><P><T><L><L><F><T><N><A><G><M><N><Q><F><K><D><V><F><L><G><F><D><K><R><P><Y><S><R><A><T><T><S><Q><K><C><V><R><A><G><G><K><H><N><D><L><E><N><V><G><Y><T><A><R><H><H><T><F><F><E><M><L><G><N><F><S><F><G><D><Y><F><K><R><D><A><I><T... | Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP> | A1K991 |
Q5FM92 | EFG_LACAC | Elongation factor G | Lactobacillus | <M><A><N><K><R><E><F><P><L><A><K><T><R><N><I><G><I><M><A><H><I><D><A><G><K><T><T><T><T><E><R><I><L><Y><Y><T><G><K><I><H><K><I><G><E><T><H><E><G><D><S><Q><M><D><W><M><D><E><E><K><E><R><G><I><T><I><T><S><A><A><T><T><A><Q><W><K><D><Y><R><I><N><I><I><D><T><P><G><H><V><D><F><T><I><E><V><E><R><S><L><R><V><L><D><G><A><V><T><V... | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective... | Q5FM92 |
B6EGG8 | SYDP_ALISL | Protein Syd | Aliivibrio | <M><P><L><S><V><E><Q><A><L><A><N><F><S><Q><R><Y><V><E><A><W><K><E><K><H><D><S><L><P><I><N><E><E><L><V><G><L><A><S><P><C><I><D><E><T><R><N><L><E><V><L><W><Q><P><V><A><R><D><E><S><I><R><L><V><N><I><E><N><G><I><E><L><D><L><H><D><D><F><H><A><F><Y><G><A><Q><F><S><A><D><M><T><A><K><F><E><G><M><N><V><E><L><L><Q><I><W><S><D><E... | Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.<BOP> | B6EGG8 |
G2Q4H7 | MA26A_MYCTT | GH26 family endo-beta-mannanase | Thermothelomyces | <M><A><R><T><L><R><Y><L><L><C><G><I><L><A><L><A><A><G><S><N><A><V><P><A><A><R><G><S><T><R><A><A><P><A><A><E><P><S><T><S><A><T><T><Y><E><A><E><D><A><I><L><S><G><T><T><V><D><T><A><Q><E><G><Y><T><G><S><G><Y><V><T><G><F><D><E><A><S><D><K><I><T><F><E><V><E><S><E><A><T><K><L><Y><D><L><S><I><R><I><A><A><I><Y><G><D><K><H><T><T... | Mannan endo-1,4-beta-mannosidase that exhibits high activity against konjac glucomannan and carob galactomannan, as well as a lower activity toward beta-mannan . Shows no activity against barley beta-glucan, birchwood xylan, and low viscosity carboxymethyl cellulose (CMC) . Has the ability to hydrolyze manno-oligosacch... | G2Q4H7 |
B6I7J5 | AIS_ECOSE | Lipopolysaccharide core heptose(II)-phosphate phosphatase | Escherichia | <M><L><A><F><C><R><S><S><L><K><S><K><K><Y><F><I><I><L><L><A><L><A><A><I><A><G><L><G><T><H><A><A><W><S><S><N><G><L><P><R><I><D><N><K><T><L><A><R><L><A><Q><Q><H><P><V><V><V><L><F><R><H><A><E><R><C><D><R><S><T><N><Q><C><L><S><D><K><T><G><I><T><V><K><G><T><Q><D><A><R><E><L><G><N><A><F><S><A><D><I><P><D><F><D><L><Y><S><S><N... | Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.<BOP> | B6I7J5 |
P34232 | MTR2_YEAST | mRNA transport regulator MTR2 | Saccharomyces | <M><N><T><N><S><N><T><M><V><M><N><D><A><N><Q><A><Q><I><T><A><T><F><T><K><K><I><L><A><H><L><D><D><P><D><S><N><K><L><A><Q><F><V><Q><L><F><N><P><N><N><C><R><I><I><F><N><A><T><P><F><A><Q><A><T><V><F><L><Q><M><W><Q><N><Q><V><V><Q><T><Q><H><A><L><T><G><V><D><Y><H><A><I><P><G><S><G><T><L><I><C><N><V><N><C><K><V><R><F><D><E><S... | Affects mRNA transport from the nucleus to the cytoplasm.<BOP> | P34232 |
A2ANU3 | SYNG1_MOUSE | Transmembrane protein 90B | Mus | <M><D><G><I><I><E><Q><K><S><V><L><V><H><S><K><I><S><D><A><G><K><R><N><G><L><I><N><T><R><N><F><M><A><E><S><R><D><G><L><V><S><V><Y><P><A><P><Q><Y><Q><S><H><R><L><V><A><S><A><A><P><G><S><L><E><G><G><R><S><E><P><V><Q><Q><L><L><D><P><N><T><L><Q><Q><S><V><E><S><H><Y><R><P><N><I><I><L><Y><S><D><G><V><L><R><S><W><G><D><G><V><A... | May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.<BOP> | A2ANU3 |
P37068 | OLF2_CHICK | Olfactory receptor-like protein COR2 | Gallus | <M><A><S><G><N><C><T><T><P><T><T><F><I><L><S><G><L><T><D><N><P><R><L><Q><M><P><L><F><M><V><F><L><V><I><Y><T><T><T><L><L><T><N><L><G><L><I><A><L><I><G><M><D><L><H><L><Q><T><P><M><Y><I><F><L><Q><N><L><S><F><T><D><A><A><Y><S><T><V><I><T><P><K><M><L><A><T><F><L><E><E><R><R><T><I><S><Y><V><G><C><I><L><Q><Y><F><S><F><V><L><L... | Odorant receptor.<BOP> | P37068 |
C4WXC1 | DRE2_ACYPI | Fe-S cluster assembly protein DRE2 homolog | Acyrthosiphon | <M><S><D><R><K><N><V><L><F><V><V><G><K><S><S><A><V><K><E><L><E><E><F><A><S><C><N><A><D><R><A><N><V><K><I><E><I><V><E><N><I><G><L><A><T><D><G><P><L><Y><S><A><I><L><S><G><F><G><A><D><D><N><V><S><C><D><L><N><L><L><P><T><Y><T><T><L><L><T><A><G><G><T><L><I><A><K><T><D><V><G><T><E><D><A><L><V><K><R><M><K><L><C><G><F><L><N><V... | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S sca... | C4WXC1 |
Q85PQ7 | NU2M_CYNPE | NADH dehydrogenase subunit 2 | Cynictis | <M><K><P><P><I><L><I><T><I><M><L><T><V><V><S><G><T><M><I><V><L><T><S><S><H><W><L><T><V><W><I><G><F><E><M><N><M><L><A><I><I><P><I><L><M><K><K><S><N><P><R><A><I><E><A><S><T><K><Y><L><L><T><Q><A><T><A><S><M><I><L><M><M><G><V><A><I><D><L><L><Y><S><G><Q><W><T><M><S><K><T><L><C><P><M><A><S><A><M><M><T><I><A><L><A><M><K><L><G... | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP> | Q85PQ7 |
Q2S1I3 | PCKA1_SALRD | Phosphoenolpyruvate carboxykinase (ATP) 1 | Salinibacter | <M><P><L><P><N><H><V><T><S><H><L><R><S><L><Q><L><A><P><A><A><V><H><Y><N><L><K><R><P><R><L><Y><E><E><A><L><D><R><N><E><G><Q><L><A><A><G><G><P><L><V><T><R><T><A><P><Y><T><G><R><S><P><K><D><R><F><I><V><R><D><A><S><V><A><D><Q><I><N><W><G><E><V><N><Q><P><T><D><R><A><T><F><D><H><L><H><E><R><M><A><E><H><A><E><G><R><D><L><F><V... | Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.<BOP> | Q2S1I3 |
A1AML8 | RIMP_PELPD | Ribosome maturation factor RimP | Pelobacter | <M><A><L><H><R><D><D><I><C><D><R><I><R><T><L><A><L><P><V><I><D><S><M><N><L><E><L><V><E><V><E><Y><K><R><S><G><R><E><A><V><L><R><L><F><I><D><K><E><G><G><V><T><L><D><D><C><A><D><L><S><R><E><L><S><T><L><L><D><V><E><D><L><I><P><C><E><Y><S><L><E><V><S><S><P><G><L><D><R><P><L><K><S><E><A><D><Y><E><R><F><S><G><R><L><I><K><V><R... | Required for maturation of 30S ribosomal subunits.<BOP> | A1AML8 |
Q9UTR4 | ETD1_SCHPO | Septation protein etd1 | Schizosaccharomyces | <M><G><V><V><Y><G><S><Q><Q><N><L><S><E><Y><F><Y><S><S><V><N><M><A><E><V><P><D><T><F><E><E><N><R><G><H><S><F><E><G><V><T><L><Q><R><R><H><V><K><G><M><K><S><Y><G><S><D><I><T><P><R><R><P><K><Q><L><G><L><P><K><E><V><N><T><S><E><C><I><D><Q><G><S><W><R><K><P><S><A><F><E><S><L><R><S><Y><S><R><K><F><S><K><R><I><F><S><F><I><G><V... | Involved in septation.<BOP> | Q9UTR4 |
A8AY74 | RL1_STRGC | 50S ribosomal protein L1 | Streptococcus | <M><A><K><K><S><K><Q><L><R><A><A><L><E><K><I><D><S><T><K><A><Y><S><V><E><E><A><V><A><L><A><K><E><T><N><F><A><K><F><D><A><T><V><E><V><A><Y><N><L><N><I><D><V><K><K><A><D><Q><Q><I><R><G><A><M><V><L><P><H><G><T><G><K><T><A><R><V><L><V><F><A><R><G><A><K><A><E><E><A><K><A><A><G><A><D><F><V><G><E><D><D><L><V><A><K><I><N><D><G... | Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP> | A8AY74 |
Q4GZK6 | ORR5_ORYSI | Type A response regulator 5 | Oryza sativa | <M><A><T><C><R><S><R><G><V><E><R><G><G><A><P><H><V><L><A><V><D><D><S><S><V><D><R><A><V><I><S><G><I><L><R><S><S><Q><F><R><V><T><A><V><D><S><G><K><R><A><L><E><L><L><G><S><E><P><N><V><S><M><I><I><T><D><Y><W><M><P><E><M><T><G><Y><E><L><L><K><K><V><K><E><S><S><R><L><K><E><I><P><V><V><I><M><S><S><E><N><V><S><T><R><I><N><R><C... | Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin sign... | Q4GZK6 |
C5C958 | FOLD_MICLC | Methenyltetrahydrofolate cyclohydrolase | Micrococcus | <M><T><A><K><V><L><D><G><K><A><T><A><A><A><I><K><E><E><L><R><G><R><V><A><A><L><A><E><R><G><R><T><P><G><L><G><T><L><L><V><G><E><D><A><G><S><Q><K><Y><V><A><G><K><H><R><D><C><A><E><V><G><I><E><S><I><Q><R><E><L><P><A><D><A><T><E><E><Q><I><L><D><V><V><R><E><L><N><E><D><P><A><C><T><G><Y><I><V><Q><L><P><L><P><K><H><V><D><T><Q... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | C5C958 |
Q2RHV8 | DTD_MOOTA | Gly-tRNA(Ala) deacylase | Moorella | <M><R><A><V><V><Q><R><V><K><K><A><R><V><T><V><A><G><E><E><I><A><T><I><G><P><G><L><L><V><F><L><G><V><G><Q><Q><D><G><P><A><D><V><E><Y><L><A><D><K><I><A><G><L><R><I><F><A><D><E><D><G><K><M><N><L><S><V><R><D><T><G><G><E><V><L><A><V><S><Q><F><T><L><Y><G><D><C><R><K><G><R><R><P><S><F><T><A><A><A><P><P><E><Q><A><L><N><L><Y><R... | An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec... | Q2RHV8 |
Q8IU89 | CERS3_HUMAN | Very-long-chain ceramide synthase CERS3 | Homo | <M><F><W><T><F><K><E><W><F><W><L><E><R><F><W><L><P><P><T><I><K><W><S><D><L><E><D><H><D><G><L><V><F><V><K><P><S><H><L><Y><V><T><I><P><Y><A><F><L><L><L><I><I><R><R><V><F><E><K><F><V><A><S><P><L><A><K><S><F><G><I><K><E><T><V><R><K><V><T><P><N><T><V><L><E><N><F><F><K><H><S><T><R><Q><P><L><Q><T><D><I><Y><G><L><A><K><K><C><N... | Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very- and ultra-long-chain fatty acyl-CoA (chain length greater than C22) . N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage... | Q8IU89 |
Q9GPH8 | SNMP2_MANSE | Sensory neuron membrane protein 2 | Manduca | <M><L><A><K><H><S><K><L><F><F><T><G><S><V><V><F><L><I><V><A><I><V><L><A><S><W><G><F><P><K><I><I><S><T><R><I><Q><K><S><I><Q><L><E><N><S><S><M><M><Y><D><K><W><V><K><L><P><I><P><L><I><F><K><V><Y><F><F><N><V><T><N><A><E><G><I><N><E><G><E><R><P><I><L><Q><E><I><G><P><Y><V><Y><K><Q><Y><R><E><R><T><V><L><G><Y><G><P><N><D><T><I... | Plays an olfactory role that is not restricted to pheromone sensitivity.<BOP> | Q9GPH8 |
Q9K923 | COMGC_HALH5 | ComG operon protein 3 homolog | Halalkalibacterium (ex Joshi et al. 2022) | <M><K><K><P><F><H><H><Q><A><G><F><T><L><V><E><M><M><I><V><L><M><I><I><S><I><L><L><L><V><A><L><P><S><M><T><K><N><N><E><V><A><G><D><K><G><C><E><A><T><V><K><L><L><Q><T><Q><V><H><A><Y><E><I><D><H><D><R><L><P><T><N><L><D><A><L><K><R><E><G><Y><V><E><H><T><E><C><P><N><G><K><K><L><T><L><R><N><G><V><V><A><I><S><E> | Required for transformation and DNA binding.<BOP> | Q9K923 |
Q57IS3 | UGPC_SALCH | sn-glycerol-3-phosphate import ATP-binding protein UgpC | Salmonella | <M><A><G><L><K><L><Q><A><V><T><K><S><W><D><G><K><T><Q><I><I><Q><P><L><T><L><D><V><A><D><G><E><F><I><V><M><V><G><P><S><G><C><G><K><S><T><L><L><R><M><V><A><G><L><E><R><V><T><S><G><D><I><W><I><D><R><K><R><V><T><E><M><E><P><K><D><R><G><I><A><M><V><F><Q><N><Y><A><L><Y><P><H><M><S><V><E><E><N><M><A><W><G><L><K><I><R><G><M><S... | Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system.<BOP> | Q57IS3 |
Q0I1S1 | RBSD_HAES1 | D-ribose pyranase | Histophilus | <M><K><K><T><K><L><L><N><A><S><L><S><H><H><I><A><T><L><G><H><T><E><S><L><V><I><C><D><A><G><L><P><I><S><N><Q><V><E><R><I><D><L><A><L><E><A><G><V><P><G><F><L><Q><T><V><D><V><V><I><S><E><M><F><V><E><H><A><V><V><A><K><E><I><R><E><K><N><P><Q><I><H><D><A><L><L><D><S><L><R><K><L><S><E><Q><Q><G><N><C><I><A><V><E><Y><V><E><H><E... | Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.<BOP> | Q0I1S1 |
Q62889 | NLGN3_RAT | Gliotactin homolog | Rattus | <M><W><L><Q><L><G><L><P><S><L><S><L><S><P><T><P><T><V><G><R><S><L><C><L><I><L><W><F><L><S><L><V><L><R><A><S><T><Q><A><P><A><P><T><V><N><T><H><F><G><K><L><R><G><A><R><V><P><L><P><S><E><I><L><G><P><V><D><Q><Y><L><G><V><P><Y><A><A><P><P><I><G><E><K><R><F><L><P><P><E><P><P><P><S><W><S><G><I><R><N><A><T><H><F><P><P><V><C><P... | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not ... | Q62889 |
Q5A5M7 | RBR3_CANAL | Repressed by RIM101 protein 3 | Candida | <M><I><I><F><R><K><S><F><F><T><F><W><L><L><L><N><S><V><L><A><L><V><I><T><Q><N><R><V><D><R><G><T><L><D><L><S><V><G><D><I><T><I><N><S><G><A><S><W><S><I><I><N><N><A><I><S><T><L><V><G><S><L><T><V><Q><P><N><A><G><L><Y><I><T><S><T><S><P><L><L><S><L><Q><V><T><L><T><S><L><L><S><T><I><Q><N><N><G><I><I><A><F><N><S><S><P><S><L><T... | GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.<BOP> | Q5A5M7 |
Q829U5 | TAL2_STRAW | Transaldolase 2 | Streptomyces | <M><T><D><A><L><K><R><L><S><K><E><G><V><A><I><W><L><D><D><L><S><R><K><R><I><T><S><G><N><L><A><E><L><I><D><Q><Q><H><V><V><G><V><T><T><N><P><S><I><F><Q><K><A><I><S><Q><G><D><G><Y><D><Q><Q><V><S><D><L><A><A><R><R><V><T><V><E><E><A><I><R><M><I><T><T><A><D><V><R><D><A><A><D><I><L><R><P><V><F><D><A><T><D><G><Q><D><G><R><V><S... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q829U5 |
Q7NCC0 | RS18_GLOVI | 30S ribosomal protein S18 | Gloeobacter | <M><T><S><F><G><Y><R><G><K><R><V><S><P><I><P><P><K><D><K><I><D><Y><K><E><V><D><L><L><R><K><F><I><T><E><R><G><K><I><L><P><R><R><I><T><G><L><T><A><K><Q><Q><R><D><L><T><V><A><I><K><R><A><R><L><L><A><L><L><P><F><V><N><Q><E><G> | Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP> | Q7NCC0 |
P83149 | OM4VA_VIBAL | Outer membrane protein 40Va | Vibrio | <A><E><V><F><K><S><E><E><G><S><V><D><F><Y><G><Q><L><R><P><A> | Forms pores that allow passive diffusion of small molecules across the outer membrane.<BOP> | P83149 |
Q8ZQ23 | TRHO_SALTY | tRNA hydroxylation protein O | Salmonella | <M><P><V><L><H><N><R><I><S><N><D><E><L><K><A><K><M><L><A><E><S><E><P><R><T><T><I><S><F><Y><K><Y><F><T><I><A><S><P><Q><Q><T><R><D><A><L><Y><Q><V><F><T><A><L><D><V><F><G><R><V><Y><L><A><H><E><G><I><N><A><Q><I><S><V><P><Q><S><K><L><E><T><F><R><Q><Q><L><Y><T><F><D><P><A><L><D><G><V><R><L><N><I><A><L><E><D><D><G><K><S><F><W... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | Q8ZQ23 |
Q4ZNZ9 | ARGJ_PSEU2 | Arginine biosynthesis bifunctional protein ArgJ beta chain | Pseudomonas syringae | <M><A><V><G><L><G><P><L><P><A><L><H><P><V><P><G><F><E><L><G><I><S><S><A><G><I><K><R><P><G><R><K><D><V><V><V><M><R><C><A><E><G><S><S><V><A><G><V><F><T><L><N><A><F><C><A><A><P><V><I><L><A><K><Q><R><V><Q><G><T><V><R><Y><L><L><T><N><T><G><N><A><N><A><G><T><G><E><P><G><L><A><A><A><R><R><T><C><E><K><L><A><Q><L><T><G><V><D><A... | Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.<BOP> | Q4ZNZ9 |
P15063 | MYCB_RAT | Protein B-Myc | Rattus | <M><P><L><H><V><S><L><A><N><G><N><R><D><L><D><Y><D><S><V><Q><P><Y><F><M><C><D><D><E><E><E><D><V><H><Q><Q><P><P><Q><P><P><A><P><S><E><D><I><W><K><K><F><E><L><L><P><T><P><R><P><S><P><G><H><P><G><L><Y><S><P><P><C><E><A><V><A><A><S><F><S><P><R><D><H><D><G><D><S><F><S><T><A><D><L><P><E><L><P><G><D><A><V><K><Q><S><F><V><C><D... | Seems to act as an inhibitor of cellular proliferation.<BOP> | P15063 |
O52691 | T2S1_STRCS | Type-2 restriction enzyme ScaI | Streptomyces | <M><I><N><D><Q><L><P><R><W><V><R><E><A><R><V><G><T><R><T><G><G><P><A><M><R><P><K><T><S><D><S><P><Y><F><G><W><D><S><E><D><W><P><E><V><T><R><Q><L><L><S><E><Q><P><L><S><G><D><T><L><V><D><A><V><L><A><S><W><E><S><I><F><E><S><R><L><G><S><G><F><H><I><G><T><Q><I><R><P><T><P><Q><V><M><G><F><L><L><H><A><L><I><P><L><E><L><A><N><G... | A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-AGTACT-3' and cleaves after T-3.<BOP> | O52691 |
Q72XF3 | NUOA_BACC1 | NUO1 | Bacillus cereus group | <M><A><S><V><Y><E><N><S><Y><M><I><V><L><I><F><L><L><L><G><I><L><L><P><V><V><A><L><T><L><G><R><M><L><R><P><S><K><P><S><A><A><K><A><T><T><Y><E><S><G><I><E><P><F><H><D><A><N><I><R><F><H><A><R><Y><Y><I><F><A><L><L><F><V><I><F><D><V><E><T><L><F><L><Y><P><W><A><V><A><Y><D><K><L><G><L><F><A><L><I><E><M><F><I><F><V><V><M><L><L... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar... | Q72XF3 |
Q555X4 | GNT15_DICDI | Glycosyltransferase-like protein gnt15 | Dictyostelium | <M><S><N><F><Y><N><N><N><P><R><R><N><T><F><R><L><T><E><R><I><K><K><K><P><Y><Q><T><L><I><V><F><I><L><I><F><L><F><L><Y><V><F><G><P><F><G><E><K><K><S><N><N><N><N><N><N><H><P><V><S><K><T><S><S><F><T><E><S><L><Y><T><K><F><Q><T><E><T><F><A><Y><R><A><N><G><D><L><K><K><Y><D><I><S><I><I><T><Q><F><T><V><D><R><F><D><R><I><A><M><M... | May have a role in modulating cell adhesion and glycosylation. Essential for development.<BOP> | Q555X4 |
A6W841 | RECA_KINRD | Recombinase A | Kineococcus | <M><P><A><P><A><D><R><E><K><A><L><D><A><A><L><A><A><I><D><K><N><F><G><K><G><S><V><M><R><L><G><D><E><V><R><P><P><I><E><V><I><P><T><G><S><I><S><L><D><V><A><L><G><I><G><G><L><P><R><G><R><V><V><E><I><Y><G><P><E><S><S><G><K><T><T><V><A><L><H><A><V><A><S><A><Q><K><A><G><G><I><A><A><F><I><D><A><E><H><A><L><D><P><D><Y><A><A><K... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP> | A6W841 |
Q6NHT2 | ATPD_CORDI | F-type ATPase subunit delta | Corynebacterium | <M><H><A><A><S><R><E><A><L><A><R><V><T><S><D><L><D><K><A><L><W><E><A><K><E><N><A><I><A><T><A><A><H><T><G><A><E><L><F><D><V><V><E><V><L><D><G><D><R><A><L><R><V><A><V><A><D><S><A><K><S><A><E><D><R><A><G><L><V><S><A><V><F><A><G><K><V><S><P><A><T><L><E><V><L><V><T><S><A><R><E><L><W><S><N><P><R><E><F><R><D><G><L><V><T><L><G... | This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.<BOP> | Q6NHT2 |
Q54DH8 | TAF1_DICDI | Transcription initiation factor TFIID subunit 1 | Dictyostelium | <M><A><K><D><K><E><K><K><G><N><L><T><G><F><L><F><G><N><V><K><E><S><G><E><L><D><V><E><E><N><D><Q><V><F><K><D><L><K><K><D><L><E><L><F><A><K><S><S><Q><H><I><S><F><K><K><T><I><G><I><D><E><D><D><K><N><A><V><T><D><S><V><I><V><P><D><K><N><A><L><D><Y><E><D><I><D><E><V><A><E><E><I><Q><S><T><E><N><E><I><N><K><L><N><A><D><K><L><A... | May be a component of the TFIID basal transcription factor complex.<BOP> | Q54DH8 |
A8Z655 | RSMG_SULMW | 16S rRNA 7-methylguanosine methyltransferase | Candidatus Sulcia | <M><K><E><R><I><F><N><K><Y><F><P><D><L><D><K><S><I><I><K><K><F><I><K><L><Y><K><I><H><K><F><F><N><K><K><I><N><I><I><S><N><N><S><L><N><F><F><Y><E><R><H><I><L><H><S><L><C><V><Y><K><I><C><Y><F><L><N><K><S><I><I><I><D><V><G><T><G><G><G><F><P><G><I><P><L><A><L><L><F><N><K><T><K><F><I><L><I><D><S><I><E><K><K><I><K><I><I><N><L... | Specifically methylates the N7 position of a guanine in 16S rRNA.<BOP> | A8Z655 |
A2C5M1 | Y024_PROM3 | Nucleoid-associated protein P9303_00241 | Prochlorococcus | <M><A><G><F><G><L><P><N><F><G><Q><L><T><E><A><F><R><K><A><Q><Q><I><Q><Q><N><A><Q><K><L><Q><E><E><L><D><A><M><E><I><E><G><S><S><P><D><G><R><A><S><I><W><L><S><G><N><Q><Q><P><L><R><V><R><L><E><P><S><L><L><A><E><G><Q><D><A><S><E><T><A><I><L><A><A><L><Q><S><A><Y><E><H><S><T><T><T><M><K><E><Q><M><E><E><L><T><G><G><L><N><L><N... | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | A2C5M1 |
P60403 | RL2_RHOPA | RRP-L2 | Rhodopseudomonas | <M><A><L><K><T><F><N><P><T><T><P><G><Q><R><Q><L><V><M><V><D><R><S><A><L><Y><K><G><K><P><V><K><R><L><T><E><G><K><N><S><N><G><G><R><N><N><T><G><R><I><T><V><R><F><R><G><G><G><H><K><Q><A><Y><R><L><V><D><F><K><R><T><K><V><D><V><P><A><K><V><E><R><L><E><Y><D><P><N><R><T><A><F><I><A><L><I><K><Y><E><D><G><E><Q><A><Y><I><L><A><P... | One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<... | P60403 |
B2J918 | SELO_NOSP7 | Protein adenylyltransferase SelO | Nostoc | <M><T><L><A><E><T><P><N><Y><K><N><S><S><N><P><L><L><S><L><N><Y><E><S><A><L><E><S><L><G><D><D><Y><Y><D><E><V><A><A><A><E><F><P><Q><H><I><L><R><W><R><N><D><A><L><L><P><R><L><G><L><D><P><Q><V><V><K><D><E><D><F><I><T><A><F><G><Q><F><Q><G><R><K><P><L><L><A><L><R><Y><H><G><Y><Q><F><G><E><Y><N><G><Q><L><G><D><G><R><G><F><L><Y... | Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).<BOP> | B2J918 |
Q9JKM5 | S1PR5_RAT | Sphingosine 1-phosphate receptor Edg-8 | Rattus | <M><E><S><G><L><L><R><P><A><P><V><S><E><V><I><V><L><H><Y><N><Y><T><G><K><L><R><G><A><R><Y><Q><P><G><A><G><L><R><A><D><A><A><V><C><L><A><V><C><A><F><I><V><L><E><N><L><A><V><L><L><V><L><G><R><H><P><R><F><H><A><P><M><F><L><L><L><G><S><L><T><L><S><D><L><L><A><G><A><A><Y><A><T><N><I><L><L><S><G><P><L><T><L><R><L><S><P><A><L... | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins. Displays antiproliferative effects in transfected CHO-K1 and... | Q9JKM5 |
Q9D5H4 | FTMT_MOUSE | Ferritin, mitochondrial | Mus | <M><L><S><C><F><W><F><F><S><K><H><I><S><S><A><L><M><S><L><P><R><V><L><H><R><F><T><A><P><Q><C><L><A><S><R><Y><P><L><G><P><L><L><A><S><P><R><R><L><L><A><S><V><A><S><S><Q><D><S><T><R><P><S><R><V><R><Q><N><F><H><P><D><S><E><A><A><I><N><R><Q><I><N><L><E><L><Y><A><S><Y><V><Y><L><S><M><A><Y><Y><F><S><R><D><D><V><A><L><Y><N><F... | Catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.<BOP> | Q9D5H4 |
Q5WLZ3 | RECR_ALKCK | Recombination protein RecR | Alkalihalobacillus | <M><Q><Y><P><R><P><I><A><K><L><I><E><G><F><T><R><L><P><G><I><G><P><K><T><A><S><R><L><A><F><H><V><L><D><M><K><E><D><D><V><L><E><F><A><K><A><L><V><H><A><K><R><D><L><T><Y><C><S><Q><C><H><N><I><T><D><T><D><P><C><Q><I><C><E><D><K><H><R><D><R><T><T><I><C><V><V><Q><E><S><R><D><L><I><A><M><E><K><M><R><E><Y><T><G><L><Y><H><V><L... | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.<BOP> | Q5WLZ3 |
Q3JCC5 | LEUD_NITOC | Isopropylmalate isomerase | Nitrosococcus | <M><E><P><L><T><V><V><E><G><L><V><V><P><L><D><R><A><N><V><D><T><D><A><I><I><P><K><Q><F><L><K><S><I><K><R><T><G><F><G><P><N><L><F><D><E><W><R><Y><L><D><H><G><E><P><G><K><D><C><R><H><R><P><L><N><P><E><F><V><L><N><Q><P><R><Y><Q><G><A><N><I><L><L><A><R><D><N><F><G><C><G><S><S><R><E><H><A><V><W><A><L><V><D><D><G><F><R><V><V... | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP> | Q3JCC5 |
P40687 | TOP3_SALTY | DNA topoisomerase III | Salmonella | <M><R><L><F><I><A><E><K><P><S><L><G><R><A><I><A><D><V><L><P><K><P><H><R><K><G><D><G><F><I><E><C><G><N><G><Q><V><V><T><W><C><I><G><H><L><L><E><Q><A><Q><P><D><A><Y><D><S><R><Y><A><R><W><N><L><A><D><L><P><I><V><P><E><K><W><Q><L><Q><P><R><P><S><V><T><K><Q><L><N><V><I><K><R><F><L><H><Q><A><G><E><I><I><H><A><G><D><P><D><R><E... | Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked b... | P40687 |
Q668Z7 | 5DNU_YERPS | Nucleoside 5'-monophosphate phosphohydrolase | Yersinia | <M><S><H><F><F><A><H><L><S><R><L><K><L><I><N><R><W><P><L><M><R><N><V><R><T><E><N><V><S><E><H><S><L><Q><V><A><F><V><A><H><A><L><A><I><I><K><N><R><K><F><N><G><N><L><N><A><E><R><I><A><L><L><A><M><Y><H><D><A><S><E><V><I><T><G><D><L><P><T><P><I><K><Y><H><N><P><K><I><A><H><E><Y><K><K><I><E><K><V><A><Q><Q><K><L><I><E><M><L><P... | Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.<BOP> | Q668Z7 |
Q4FR92 | SYS_PSYA2 | Seryl-tRNA(Ser/Sec) synthetase | Psychrobacter | <M><I><D><P><K><L><L><R><G><D><L><T><D><L><Q><Q><Q><L><A><T><R><G><Y><T><L><D><M><A><F><W><Q><S><I><E><N><E><R><K><S><L><Q><V><Q><T><E><E><L><Q><S><R><R><N><A><G><A><K><Q><V><G><A><L><K><K><S><G><E><D><T><S><E><L><L><A><D><M><Q><S><V><S><G><E><I><K><T><A><E><D><E><L><R><T><L><Q><E><R><I><N><Q><A><A><L><Q><I><P><N><I><P... | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP> | Q4FR92 |
P55114 | NAS33_CAEEL | Nematode astacin 33 | Caenorhabditis | <M><L><F><V><S><I><L><I><S><Q><F><V><T><C><L><T><Q><P><D><F><F><E><R><P><P><P><P><D><W><F><F><P><G><P><L><R><P><W><G><P><P><P><P><W><H><R><N><R><G><P><P><P><F><G><P><P><P><P><W><D><R><P><P><P><P><W><R><R><P><P><W><H><R><R><P><P><W><G><L><P><P><P><P><P><P><P><E><P><E><P><Q><Q><D><Q><P><Q><V><M><F><S><Q><D><I><D><K><V><V... | Metalloprotease.<BOP> | P55114 |
P0CAR5 | 3S1E3_MICPY | Weak neurotoxin E3 | Micrurus | <L><I><C><F><N><D><F><S><P><T><A><R><T><L><E><Y><C><Q><I><G><I><T><T><Y><N><P><S> | Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.<BOP> | P0CAR5 |
Q8FS34 | RS4_COREF | 30S ribosomal protein S4 | Corynebacterium | <M><A><R><Y><T><G><P><A><T><R><K><S><R><R><L><R><V><D><L><V><G><G><D><M><A><F><E><R><R><P><Y><P><P><G><Q><A><G><R><A><R><I><K><E><S><E><Y><L><L><Q><L><Q><E><K><Q><K><A><R><F><I><Y><G><V><M><E><K><Q><F><R><R><Y><Y><A><E><A><N><R><R><P><G><K><T><G><E><N><L><V><V><M><L><E><S><R><L><D><N><V><V><Y><R><A><G><L><A><R><T><R><R... | With S5 and S12 plays an important role in translational accuracy.<BOP> | Q8FS34 |
Q5F3V3 | PDS5A_CHICK | Sister chromatid cohesion protein PDS5 homolog A | Gallus | <M><D><F><P><A><A><Q><P><K><P><A><A><D><G><K><I><I><Y><Y><P><P><G><V><K><E><T><T><D><K><I><T><N><D><E><V><V><K><R><L><K><M><V><V><K><T><F><M><D><M><D><Q><D><S><E><D><E><K><Q><Q><Y><L><P><L><A><L><H><L><A><S><E><F><F><L><R><N><P><N><K><D><V><R><L><L><V><A><C><C><L><A><D><I><F><R><I><Y><A><P><E><A><P><Y><T><S><H><D><K><L... | May regulate sister chromatid cohesion during mitosis and couple it to DNA replication.<BOP> | Q5F3V3 |
Q7UN32 | RS12_RHOBA | 30S ribosomal protein S12 | Rhodopirellula | <M><P><T><I><N><Q><L><V><R><K><N><R><K><Q><K><K><S><Q><S><K><S><P><V><L><E><K><C><P><Q><K><Q><G><V><C><L><Q><V><R><T><M><T><P><K><K><P><N><S><A><L><R><K><I><T><R><V><R><L><S><N><G><K><E><V><T><V><Y><I><P><G><E><G><H><N><L><Q><E><H><S><I><V><L><V><R><G><G><R><V><R><D><L><P><G><V><R><Y><Q><V><V><R><G><S><R><D><A><L><G><V... | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | Q7UN32 |
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