accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
C0MDT1
GLMM_STRS7
Phosphoglucosamine mutase
Streptococcus
<M><G><K><Y><F><G><T><D><G><V><R><G><E><A><N><V><E><L><T><P><E><L><A><F><K><L><G><R><F><G><G><Y><V><L><S><Q><H><E><T><E><R><P><R><V><F><V><A><R><D><T><R><I><S><G><E><M><L><E><A><A><L><I><A><G><L><L><S><V><G><I><E><V><Y><K><L><G><V><L><A><T><P><G><V><S><Y><L><V><R><T><E><K><A><S><A><G><V><M><I><S><A><S><H><N><P><A><L><D...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
C0MDT1
B3PC08
GATA_CELJU
Glutamyl-tRNA(Gln) amidotransferase subunit A
Cellvibrio
<M><H><Q><F><T><I><A><E><L><V><K><G><L><R><N><K><D><F><S><S><T><E><I><T><Q><H><Y><L><D><R><I><A><R><L><D><N><T><Y><N><S><Y><I><T><V><T><G><D><V><A><L><Q><Q><A><A><A><A><D><K><R><L><A><A><G><N><T><S><A><L><C><G><V><P><I><A><H><K><D><I><F><C><T><A><G><V><R><T><S><C><A><S><K><M><L><D><K><F><I><A><P><Y><N><A><T><I><V><E><N...
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP>
B3PC08
Q7KTX7
PRKN_DROME
E3 ubiquitin-protein ligase parkin
Sophophora
<M><S><F><I><F><K><F><I><A><T><F><V><R><K><M><L><E><L><L><Q><F><G><G><K><T><L><T><H><T><L><S><I><Y><V><K><T><N><T><G><K><T><L><T><V><N><L><E><P><Q><W><D><I><K><N><V><K><E><L><V><A><P><Q><L><G><L><Q><P><D><D><L><K><I><I><F><A><G><K><E><L><S><D><A><T><T><I><E><Q><C><D><L><G><Q><Q><S><V><L><H><A><I><R><L><R><P><P><V><Q><R...
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as Paris, Marf, Opa1, Miro, pnut, Sep1, Tom20 and porin . Mediates monoubiquitination as well as 'Lys-6', 'Lys-11', 'Lys-48'-linked ...
Q7KTX7
P27182
ATPL_SYNY3
Lipid-binding protein
unclassified Synechocystis
<M><D><S><T><V><A><A><A><S><V><I><A><A><A><L><A><V><G><L><G><A><I><G><P><G><I><G><Q><G><N><A><S><G><Q><A><V><S><G><I><A><R><Q><P><E><A><E><G><K><I><R><G><T><L><L><L><T><L><A><F><M><E><S><L><T><I><Y><G><L><V><I><A><L><V><L><L><F><A><N><P><F><A>
Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.<BOP>
P27182
P47632
CH60_MYCGE
Chaperonin-60
Mycoplasma
<M><A><K><E><L><I><F><G><K><D><A><R><T><R><L><L><Q><G><I><N><K><I><A><N><A><V><K><V><T><V><G><P><K><G><Q><N><V><I><L><E><R><K><F><A><N><P><L><I><T><N><D><G><V><T><I><A><K><E><I><E><L><S><D><P><V><E><N><I><G><A><K><V><I><S><V><A><A><V><S><T><N><D><I><A><G><D><G><T><T><T><A><T><I><L><A><Q><E><M><T><N><R><G><I><E><I><I><N...
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP>
P47632
P27439
MSP1_ASCSU
Alpha-MSP
Ascaris
<M><A><Q><S><V><P><P><G><D><I><N><T><Q><P><S><Q><K><I><V><F><N><A><P><Y><D><D><K><H><T><Y><H><I><K><I><T><N><A><G><G><R><R><I><G><W><A><I><K><T><T><N><M><R><R><L><S><V><D><P><P><C><G><V><L><D><P><K><E><K><V><L><M><A><V><S><C><D><T><F><N><A><A><T><E><D><L><N><N><D><R><I><T><I><E><W><T><N><T><P><D><G><A><A><K><Q><F><R><R...
Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.<BOP>
P27439
B5Y305
RL9_KLEP3
50S ribosomal protein L9
Klebsiella
<M><Q><V><I><L><L><D><K><V><A><N><L><G><S><L><G><D><Q><V><N><V><K><A><G><Y><A><R><N><F><L><V><P><Q><G><K><A><V><P><A><T><K><K><N><V><E><F><F><E><A><R><R><A><E><L><E><A><K><L><A><D><V><L><S><A><A><E><A><R><A><A><Q><I><N><A><L><E><S><V><T><I><A><S><K><A><G><D><E><G><K><L><F><G><S><I><G><T><R><D><I><A><D><A><V><T><A><A><G...
Binds to the 23S rRNA.<BOP>
B5Y305
Q3A829
HISZ_SYNC1
ATP phosphoribosyltransferase regulatory subunit
Syntrophotalea
<M><N><R><K><I><T><V><P><E><A><M><L><P><R><G><V><K><D><F><L><P><N><K><A><A><K><L><E><Y><L><K><Q><S><L><K><D><V><F><H><R><W><A><F><R><P><I><M><P><P><T><L><E><Y><L><D><V><L><E><R><G><L><G><A><G><L><R><D><K><T><F><R><F><D><D><R><Q><N><G><K><L><V><A><F><C><P><D><I><T><P><Q><V><A><R><I><V><A><T><R><M><K><G><A><P><L><P><Q><R...
Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.<BOP>
Q3A829
Q9Y6K5
OAS3_HUMAN
p100 OAS
Homo
<M><D><L><Y><S><T><P><A><A><A><L><D><R><F><V><A><R><R><L><Q><P><R><K><E><F><V><E><K><A><R><R><A><L><G><A><L><A><A><A><L><R><E><R><G><G><R><L><G><A><A><A><P><R><V><L><K><T><V><K><G><G><S><S><G><R><G><T><A><L><K><G><G><C><D><S><E><L><V><I><F><L><D><C><F><K><S><Y><V><D><Q><R><A><R><R><A><E><I><L><S><E><M><R><A><S><L><E><S...
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) ...
Q9Y6K5
P56377
AP1S2_HUMAN
Sigma1B-adaptin
Homo
<M><Q><F><M><L><L><F><S><R><Q><G><K><L><R><L><Q><K><W><Y><V><P><L><S><D><K><E><K><K><K><I><T><R><E><L><V><Q><T><V><L><A><R><K><P><K><M><C><S><F><L><E><W><R><D><L><K><I><V><Y><K><R><Y><A><S><L><Y><F><C><C><A><I><E><D><Q><D><N><E><L><I><T><L><E><I><I><H><R><Y><V><E><L><L><D><K><Y><F><G><S><V><C><E><L><D><I><I><F><N><F><E...
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo mole...
P56377
Q6G2X2
RL16_BARHE
50S ribosomal protein L16
Bartonella
<M><L><Q><P><K><R><T><R><F><R><K><Q><F><K><G><R><I><H><G><V><S><K><G><G><T><D><L><N><F><G><A><Y><G><L><K><A><V><E><P><E><R><I><T><A><R><Q><I><E><A><A><R><R><A><I><T><R><Y><M><K><R><S><G><R><V><W><I><R><I><F><P><D><L><P><V><T><S><K><P><T><E><V><R><M><G><K><G><K><G><S><V><D><Y><W><A><A><R><V><A><P><G><R><I><M><F><E><L><D...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
Q6G2X2
O33570
CCMA_CERS4
Heme exporter protein A
Cereibacter
<M><D><L><T><V><T><N><L><A><C><A><R><G><G><V><T><V><L><E><R><V><S><F><R><L><S><R><G><A><A><L><I><L><R><G><P><N><G><I><G><K><T><T><L><L><R><T><V><A><G><L><Q><P><A><V><A><G><E><I><S><M><P><P><E><A><V><A><Y><A><A><H><A><D><G><L><K><A><T><L><T><V><A><E><N><L><A><F><W><A><A><I><Y><G><T><D><R><A><A><R><A><I><E><R><M><N><L><A...
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.<BOP>
O33570
P64688
AC100_MYCBO
Acyl carrier protein BQ2027_MB0103
Mycobacterium tuberculosis complex
<M><R><D><R><I><L><A><A><V><C><D><V><L><Y><I><D><E><A><D><L><I><D><G><D><E><T><D><L><R><D><L><G><L><D><S><V><R><F><V><L><L><M><K><Q><L><G><V><N><R><Q><S><E><L><P><S><R><L><A><A><N><P><S><I><A><G><W><L><R><E><L><E><A><V><C><T><E><F><G>
Acyl carrier protein that accepts acyl-adenylates (acyl-AMP) from FadD10.<BOP>
P64688
Q9RRB6
SLPA_DEIRA
S-layer protein SlpA
Deinococcus
<M><K><K><S><L><I><A><L><T><T><A><L><S><F><G><L><A><A><A><Q><T><A><A><P><V><S><A><P><Q><V><P><A><L><T><D><V><P><A><G><H><W><A><K><D><A><I><D><R><L><V><S><R><G><V><I><L><G><Y><P><D><G><T><F><R><G><T><Q><N><L><T><R><Y><E><A><A><I><I><I><A><R><L><L><D><Q><M><R><D><G><E><T><P><A><G><M><T><A><E><D><M><T><A><L><Q><N><A><I><Q...
Major constituent of the S-layer. Plays an important role in the structural organization and integrity of the S-layer . Binds the carotenoid deinoxanthin, a strong protective antioxidant specific of this bacterium, and could be part of the first lane of defense against UV radiation, especially under desiccation .<BOP>
Q9RRB6
Q1INZ5
GVPA_KORVE
Gas vesicle structural protein
Candidatus Koribacter
<M><A><V><E><R><V><S><G><G><S><S><L><I><D><V><L><D><R><V><L><D><K><G><I><V><I><D><A><W><V><R><I><S><L><V><G><I><D><L><I><T><V><E><A><R><V><V><V><A><S><I><D><T><Y><L><K><Y><A><D><A><V><G><L><T><G><L><V><S><R><P><Q><L><T><E><V><V><E><E><P><V><V><V><E><A><P><A><T><R><R><T><A><R><P><S><R><R><R><I>
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.<BOP>
Q1INZ5
Q8CE23
OX26_MOUSE
Pyroglutamylated arginine-phenylalanine-amide peptide
Mus
<M><R><G><F><R><P><L><L><S><L><L><L><P><L><S><A><C><F><P><L><L><D><R><R><G><P><T><D><I><G><D><I><G><A><R><M><N><W><A><Q><L><A><E><G><H><P><P><N><S><V><Q><N><P><Q><P><Q><A><L><L><V><V><A><R><E><Q><Q><A><S><H><R><E><H><T><G><F><R><L><G><R><Q><D><G><S><S><E><A><A><G><F><L><P><A><D><S><E><K><A><S><G><P><L><G><T><L><A><E><E...
Stimulates feeding and grooming behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland.<BOP>
Q8CE23
A5FY70
QUEF_ACICJ
PreQ(0) reductase
Acidiphilium
<M><T><D><T><R><Y><D><A><L><Q><Q><L><G><R><E><S><R><M><P><D><S><P><E><A><A><V><L><E><R><V><A><A><P><S><R><G><K><N><Y><V><V><R><F><T><C><P><E><F><T><S><L><C><P><I><T><G><Q><P><D><F><A><H><V><V><I><D><Y><I><P><D><S><W><I><V><E><S><K><S><L><K><L><Y><L><G><S><F><R><N><H><G><A><F><H><E><A><C><T><L><M><I><A><E><R><L><V><D><L...
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP>
A5FY70
Q66EM6
SGRR_YERPS
HTH-type transcriptional regulator SgrR
Yersinia
<M><S><T><S><R><L><Q><Q><Q><F><I><R><L><W><Q><R><Y><N><G><Q><S><T><E><T><T><L><Q><A><L><A><E><V><L><N><C><S><R><R><H><V><R><S><L><L><G><K><M><Q><H><A><G><W><L><D><W><Q><A><E><A><G><R><G><K><R><S><Q><L><I><F><L><R><S><G><L><A><L><Q><Q><Q><R><A><E><E><L><L><E><Q><D><H><I><D><Q><L><V><Q><L><V><G><D><K><K><A><V><R><Q><M><L...
Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.<BOP>
Q66EM6
Q8YCY1
OCD_BRUME
Ornithine cyclodeaminase
Brucella
<M><M><T><Q><P><N><L><N><I><V><P><F><V><S><V><D><H><M><M><K><L><V><L><R><V><G><V><E><T><F><L><K><E><L><A><G><Y><V><E><E><D><F><R><R><W><Q><N><F><D><K><T><P><R><V><A><S><H><S><K><E><G><V><I><E><L><M><P><T><S><D><G><T><L><Y><G><F><K><Y><V><N><G><H><P><K><N><T><R><D><G><L><Q><T><V><T><A><F><G><V><L><A><D><V><G><S><G><Y><P...
Catalyzes the conversion of L-ornithine into L-proline with release of ammonia.<BOP>
Q8YCY1
Q5P1F7
GLMM_AROAE
Phosphoglucosamine mutase
Aromatoleum
<M><G><R><K><Y><F><G><T><D><G><V><R><G><R><V><G><D><S><T><I><T><P><E><F><V><M><R><L><G><Y><A><A><G><V><T><L><V><G><R><E><Q><L><P><P><G><E><R><P><A><I><L><I><G><K><D><T><R><I><S><G><Y><M><L><E><A><A><L><E><A><G><F><A><A><A><G><V><D><V><M><L><A><G><P><V><P><T><P><A><V><A><Y><L><T><R><A><L><R><L><Q><A><G><V><V><I><S><A><S...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
Q5P1F7
Q6NRB9
EMC1_XENLA
ER membrane protein complex subunit 1
Xenopus
<M><A><A><D><L><C><W><L><S><L><L><L><A><S><L><A><L><S><G><A><V><Y><E><D><Q><V><G><K><F><D><W><R><Q><E><Y><V><G><R><I><K><F><A><S><L><E><S><G><L><G><A><K><K><L><I><A><V><T><D><K><N><I><I><A><A><L><N><S><R><T><G><D><L><L><W><R><H><V><D><K><D><T><S><E><G><T><V><D><A><L><M><M><I><G><Q><D><A><I><T><V><S><G><G><R><L><L><R><S...
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such a...
Q6NRB9
O60683
PEX10_HUMAN
RING finger protein 69
Homo
<M><A><P><A><A><A><S><P><P><E><V><I><R><A><A><Q><K><D><E><Y><Y><R><G><G><L><R><S><A><A><G><G><A><L><H><S><L><A><G><A><R><K><W><L><E><W><R><K><E><V><E><L><L><S><D><V><A><Y><F><G><L><T><T><L><A><G><Y><Q><T><L><G><E><E><Y><V><S><I><I><Q><V><D><P><S><R><I><H><V><P><S><S><L><R><R><G><V><L><V><T><L><H><A><V><L><P><Y><L><L><D...
Somewhat implicated in the biogenesis of peroxisomes.<BOP>
O60683
Q88NI1
MCPU_PSEPK
Methyl-accepting chemotaxis protein McpU
Pseudomonas
<M><P><L><R><R><L><S><I><Q><W><K><I><T><L><L><A><G><L><C><L><L><A><I><V><A><L><L><V><A><T><S><L><T><Q><A><H><R><S><A><A><L><V><N><Q><A><N><T><A><M><L><E><D><S><A><R><Q><R><L><Q><A><H><A><E><T><Q><A><L><R><I><Q><R><Y><F><M><D><A><Y><Q><Y><G><N><G><F><A><R><L><V><Q><V><L><K><D><R><G><G><S><D><L><R><A><E><L><T><R><Q><A><R...
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpU is a chemoreceptor that binds and mediates che...
Q88NI1
Q71G51
TBA_NEOCA
Alpha-tubulin
Neospora
<M><R><E><V><I><S><I><H><V><G><Q><A><G><I><Q><I><G><N><A><C><W><E><L><F><C><L><E><H><G><I><Q><P><D><G><Q><M><P><S><D><K><T><I><G><G><G><D><D><A><F><N><T><F><F><S><E><T><G><A><G><K><H><V><P><R><C><V><F><L><D><L><E><P><T><V><V><D><E><V><R><T><G><T><Y><R><H><L><F><H><P><E><Q><L><I><S><G><K><E><D><A><A><N><N><F><A><R><G><H...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
Q71G51
Q9PHW9
HEM3_CAMJE
Pre-uroporphyrinogen synthase
Campylobacter
<M><K><L><I><I><A><T><R><K><S><Q><L><A><L><W><Q><S><E><H><V><A><Q><I><L><K><N><T><H><Q><I><E><V><L><L><E><G><F><K><T><K><G><D><V><L><L><D><S><P><L><A><K><I><G><G><K><G><L><F><T><K><E><L><E><E><S><M><L><R><K><E><A><H><L><A><V><H><S><L><K><D><V><P><S><F><F><P><Q><G><L><V><L><A><A><V><S><K><R><E><Q><S><N><D><A><M><L><S><Q...
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP>
Q9PHW9
A5EYG3
DNAK_DICNV
Heat shock protein 70
Dichelobacter
<M><G><K><I><I><G><I><D><L><G><T><T><N><S><C><V><A><V><M><D><G><D><S><A><K><V><I><E><N><S><E><G><T><R><T><T><P><S><I><I><A><F><S><D><G><E><V><L><V><G><Q><P><A><K><R><Q><A><V><T><N><P><K><N><T><L><Y><A><I><K><R><L><I><G><R><R><F><D><E><K><E><V><Q><K><D><I><N><L><V><P><Y><N><I><V><K><S><D><N><G><D><A><W><V><E><I><D><G><K...
Acts as a chaperone.<BOP>
A5EYG3
A7M9A9
CCSA_CUSRE
Cytochrome c biogenesis protein CcsA
Cuscuta subgen. Monogynella
<M><I><V><S><T><L><E><H><I><L><T><H><I><S><L><S><I><V><S><I><L><I><T><I><E><L><R><I><F><L><D><D><E><I><K><K><L><Y><D><S><S><E><R><G><M><L><I><T><F><L><C><I><T><G><L><L><A><N><N><W><I><Y><L><G><H><F><P><L><S><D><L><S><E><S><L><I><F><L><S><W><S><F><A><L><I><H><S><I><G><Y><F><T><K><N><L><K><F><L><S><T><I><T><S><Q><S><T><L...
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.<BOP>
A7M9A9
Q1GJX2
YIDD_RUEST
Putative membrane protein insertion efficiency factor
unclassified Ruegeria
<M><R><L><L><A><R><L><I><A><L><P><V><R><G><Y><R><L><L><F><S><P><W><V><G><F><N><C><R><Y><Q><P><T><C><S><A><Y><A><L><D><A><L><E><R><H><G><P><F><K><G><T><Y><L><M><L><R><R><I><G><R><C><H><P><F><G><G><S><G><Y><D><P><V><P><G><A><D><P><K><H><D><R><C><C><G><R><T><P>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q1GJX2
B4K8J8
SPC25_DROMO
Kinetochore protein Spc25
Drosophila
<M><R><K><R><L><M><A><M><L><Q><N><D><I><S><L><Q><Q><Q><E><N><A><L><A><K><Q><S><A><K><F><H><S><K><I><A><A><K><H><Q><L><I><K><R><Q><Q><R><K><L><E><K><L><N><Q><V><A><N><E><R><K><E><D><Q><E><N><R><S><A><F><E><Q><S><M><R><D><K><L><L><R><E><Q><Q><N><L><S><E><M><Q><T><E><L><A><T><K><K><Q><R><R><D><E><L><M><G><F><V><R><T><M><S...
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Participa...
B4K8J8
Q1JHB7
DEOB_STRPD
Phosphodeoxyribomutase
Streptococcus
<M><S><K><F><N><R><I><H><L><V><V><L><D><S><V><G><I><G><A><A><P><D><A><D><K><F><F><N><A><G><V><A><D><T><D><S><D><T><L><G><H><I><S><E><T><A><G><L><S><V><P><N><M><A><K><I><G><L><G><N><I><S><R><P><I><P><L><K><T><V><P><T><E><D><N><P><T><G><Y><V><T><K><L><E><E><V><S><L><G><K><D><T><M><T><G><H><W><E><I><M><G><L><N><I><T><E><P...
Phosphotransfer between the C1 and C5 carbon atoms of pentose.<BOP>
Q1JHB7
Q9SLF7
RLA22_ARATH
60S acidic ribosomal protein P2-2
Arabidopsis
<M><K><V><V><A><A><Y><L><L><A><V><L><S><G><K><A><S><P><T><S><A><D><I><K><T><I><L><G><S><V><G><A><E><T><E><D><S><Q><I><E><L><L><L><K><E><V><K><G><K><D><L><A><E><L><I><A><A><G><R><E><K><L><A><S><V><P><S><G><G><G><G><G><V><A><V><A><S><A><T><S><G><G><G><G><G><G><G><A><S><A><A><E><S><K><K><E><E><K><K><E><E><K><E><E><S><D><D...
Plays an important role in the elongation step of protein synthesis.<BOP>
Q9SLF7
Q9UU89
ITPA_SCHPO
Nucleoside-triphosphate pyrophosphatase
Schizosaccharomyces
<M><T><I><L><Q><S><I><L><F><V><T><G><N><K><H><K><L><A><D><V><K><N><I><L><G><D><R><F><E><I><K><N><H><D><Y><D><L><P><E><I><Q><G><S><V><K><E><V><V><L><E><K><C><K><A><A><A><E><I><V><K><G><P><V><L><V><E><D><T><W><L><G><Y><K><A><M><N><G><L><P><G><P><Y><V><K><W><F><L><N><S><V><G><P><D><G><L><Y><R><M><V><S><A><F><D><T><K><E><A...
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical pu...
Q9UU89
Q6FCR9
ILVD1_ACIAD
Dihydroxy-acid dehydratase 1
Acinetobacter
<M><P><D><Y><R><S><K><T><S><T><H><G><R><N><M><A><G><A><R><G><L><W><R><A><T><G><M><K><D><E><D><F><G><K><P><I><I><A><V><V><N><S><F><T><Q><F><V><P><G><H><V><H><L><K><D><L><G><Q><M><V><A><E><Q><I><Q><A><A><G><G><V><A><K><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><D><G><M><L><Y><S><L><P><S><R><D><L><I><A><D><S><V><E><Y><M...
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (...
Q6FCR9
Q8PJZ7
EFP_XANAC
Elongation factor P
Xanthomonas
<M><A><T><V><G><M><N><D><V><K><N><G><M><K><I><L><V><N><N><E><P><A><V><I><T><E><T><E><Y><V><K><P><G><K><G><Q><A><F><T><R><M><K><Y><R><F><I><K><S><G><R><V><V><E><M><T><M><K><A><T><D><D><V><E><V><A><D><V><V><D><T><D><M><R><Y><L><Y><S><D><G><E><Y><W><H><F><M><D><P><D><T><F><E><Q><V><Q><T><D><K><A><G><M><G><G><A><D><K><W><L...
Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.<BOP>
Q8PJZ7
Q8KEX2
NADE_CHLTE
NH(3)-dependent NAD(+) synthetase
Chlorobaculum
<M><K><P><Q><N><L><H><F><D><Y><G><L><V><E><A><I><L><V><P><F><I><R><N><E><I><R><K><F><G><F><G><S><V><V><L><G><L><S><G><G><I><D><S><A><V><V><C><E><L><A><V><R><A><L><G><V><E><N><V><L><A><L><M><M><P><Y><K><T><S><S><Q><E><S><L><D><H><A><E><L><M><V><D><R><L><G><I><R><Y><E><I><M><P><V><T><E><V><V><D><A><F><F><A><T><R><P><D><A...
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.<BOP>
Q8KEX2
A8A5F1
TUSC_ECOHS
tRNA 2-thiouridine synthesizing protein C
Escherichia
<M><K><R><I><A><F><V><F><S><T><A><P><H><G><T><A><A><G><R><E><G><L><D><A><L><L><A><T><S><A><L><T><D><D><L><A><V><F><F><I><A><D><G><V><F><Q><L><L><S><G><Q><K><P><D><A><V><L><A><R><D><Y><I><A><T><F><K><L><L><G><L><Y><D><I><E><Q><C><W><V><C><A><A><S><L><R><E><R><G><L><D><P><Q><T><P><F><V><V><E><A><T><P><L><E><A><D><A><L><R...
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.<BOP>
A8A5F1
A2BTX3
EFP_PROM5
Elongation factor P
Prochlorococcus
<M><I><S><S><N><D><F><R><T><G><T><T><I><E><I><D><G><Q><V><W><R><V><V><E><F><L><H><V><K><P><G><K><G><S><A><F><V><R><T><K><L><K><S><V><R><N><G><N><V><V><E><K><T><F><R><A><G><E><S><V><Q><Q><A><V><L><E><K><S><N><L><Q><H><T><Y><V><E><S><G><D><Y><V><F><M><D><M><T><S><F><E><E><T><R><L><S><S><D><Q><I><G><R><G><S><K><Y><L><K><E...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
A2BTX3
Q4A734
TSAD_MYCS5
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Mycoplasmopsis
<M><I><I><L><G><I><E><T><S><H><D><D><S><S><I><A><I><L><E><D><G><K><V><L><N><M><W><S><I><S><Q><I><D><I><F><K><K><Y><G><G><T><I><P><E><I><A><S><R><E><H><V><K><N><I><A><I><L><Q><N><F><L><Q><E><F><I><D><L><N><K><I><D><H><I><A><Y><T><S><E><P><G><L><I><G><C><L><Q><V><G><F><L><F><A><S><A><L><S><I><A><L><N><K><P><L><I><K><I><N...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q4A734
A0A0B4J245
TVAL1_HUMAN
T cell receptor alpha variable 12-1
Homo
<M><I><S><L><R><V><L><L><V><I><L><W><L><Q><L><S><W><V><W><S><Q><R><K><E><V><E><Q><D><P><G><P><F><N><V><P><E><G><A><T><V><A><F><N><C><T><Y><S><N><S><A><S><Q><S><F><F><W><Y><R><Q><D><C><R><K><E><P><K><L><L><M><S><V><Y><S><S><G><N><E><D><G><R><F><T><A><Q><L><N><R><A><S><Q><Y><I><S><L><L><I><R><D><S><K><L><S><D><S><A><T><Y...
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (...
A0A0B4J245
O15998
ACTM_CIOSA
Actin, muscle
Ciona
<M><S><D><S><E><E><D><Q><T><A><L><V><C><D><N><G><S><G><L><V><K><S><G><F><A><G><D><D><A><P><R><A><V><F><P><S><I><V><G><R><P><R><H><Q><G><V><M><V><G><M><G><Q><K><D><S><Y><V><G><D><E><A><Q><S><K><R><G><I><L><T><L><K><Y><P><I><E><H><G><I><I><T><N><W><D><D><M><E><K><I><W><H><H><T><F><Y><N><E><L><R><V><A><P><E><E><H><P><T><L...
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.<BOP>
O15998
Q22058
HRDE2_CAEEL
Heritable RNAi deficient protein 2
Caenorhabditis
<M><S><Q><N><S><D><T><F><D><S><G><L><Q><M><E><V><H><K><M><A><E><A><D><N><S><S><V><Q><Q><K><F><D><A><I><R><D><Y><I><G><R><K><E><T><T><I><I><L><C><E><H><D><D><S><R><K><I><K><L><T><L><N><K><Q><R><M><E><S><S><M><F><L><T><E><M><P><D><G><G><I><Q><E><K><T><K><F><H><R><N><G><L><A><V><C><S><Y><N><A><F><D><E><V><D><L><P><L><A><D...
Plays a role in germline RNA interference (RNAi), and in particular is required for piwi-interacting RNA (piRNA) gene silencing. Facilitates the binding of the argonaut protein hrde-1 to small interfering RNAs (siRNAs) targets that are required for transgenerational epigenetic inheritance and germline immortality.<BOP>
Q22058
Q65Q31
RHAS_MANSM
L-rhamnose operon regulatory protein RhaS
Basfia
<M><I><Q><K><L><L><A><R><D><F><F><N><N><K><E><Q><P><I><I><L><E><P><R><A><P><Q><E><I><F><P><E><H><T><H><D><F><D><E><L><V><I><V><K><H><G><S><G><R><H><I><L><N><G><Y><P><H><D><L><Y><P><G><V><V><L><Y><I><Q><A><Q><D><H><H><S><Y><E><N><L><Q><D><L><C><L><T><N><I><L><I><Q><S><N><N><N><F><K><Y><L><N><N><I><D><I><L><L><N><G><L><K...
Activates expression of the rhaBAD and rhaT operons.<BOP>
Q65Q31
B8IEX6
MIAA_METNO
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Methylobacterium
<M><A><G><R><A><I><L><I><A><G><P><T><A><S><G><K><S><A><L><A><L><G><L><A><Q><A><R><G><G><V><V><I><N><A><D><S><M><Q><V><Y><G><D><L><R><V><L><T><A><R><P><S><P><E><E><E><E><A><A><P><H><R><L><Y><G><H><V><D><G><A><V><N><Y><S><V><G><H><Y><L><A><D><A><G><R><V><L><R><D><A><W><A><A><E><R><L><P><I><V><V><G><G><T><G><L><Y><F><K><A...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
B8IEX6
A5F649
SYE_VIBC3
Glutamyl-tRNA synthetase
Vibrio
<M><T><V><K><T><R><F><A><P><S><P><T><G><Y><L><H><V><G><G><A><R><T><A><L><Y><S><W><L><Y><A><K><S><Q><G><G><E><F><V><L><R><I><E><D><T><D><L><E><R><S><T><Q><A><A><V><D><A><I><I><E><G><M><T><W><L><G><L><E><W><D><E><G><P><Y><Y><Q><T><K><R><F><D><R><Y><N><Q><V><I><D><Q><L><L><A><E><G><K><A><Y><K><C><Y><A><P><K><E><L><L><D><E...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
A5F649
W4VRU5
ICK36_TRILK
Toxin ICK-36
Trittame
<M><K><T><I><I><V><F><L><S><L><L><V><L><A><T><K><F><G><D><A><K><E><G><V><N><Q><K><Q><K><K><E><V><T><Q><N><E><F><R><E><E><Y><L><N><E><M><A><A><M><S><L><V><Q><Q><L><E><A><I><E><R><A><L><F><E><N><E><A><G><R><N><S><R><Q><K><R><C><L><G><E><N><V><P><C><G><D><N><I><P><C><C><G><K><L><A><C><E><K><T><A><G><Y><G><W><W><Y><K><S><P...
Ion channel inhibitor.<BOP>
W4VRU5
B7VI66
RS18_VIBA3
30S ribosomal protein S18
Vibrio
<M><A><R><F><F><R><R><R><K><F><C><R><F><T><A><E><G><V><Q><E><I><D><Y><K><D><V><A><T><L><K><N><Y><I><T><E><A><G><K><I><V><P><S><R><I><T><G><T><S><A><K><Y><Q><R><Q><L><A><R><A><I><K><R><S><R><Y><L><A><L><L><P><Y><T><D><K><H><Q>
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP>
B7VI66
Q0AJA9
ATPE_NITEC
F-ATPase epsilon subunit
Nitrosomonas
<M><G><T><I><F><H><L><D><I><V><S><A><E><E><S><I><Y><S><G><P><A><E><F><I><V><A><P><A><V><M><G><E><V><G><I><Y><P><Q><H><T><P><M><L><T><R><I><K><S><G><V><V><R><V><K><A><P><L><Q><D><D><E><E><I><Y><V><S><G><G><M><L><E><V><Q><P><D><V><V><T><I><L><A><D><T><A><V><R><G><Q><D><L><D><E><A><K><A><L><E><A><K><R><K><A><E><E><I><M><K...
Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP>
Q0AJA9
Q45251
HUPD_BRADU
Hydrogenase expression/formation protein HupD
Bradyrhizobium
<M><P><T><S><S><Q><D><N><R><I><L><V><L><G><I><G><N><I><L><W><A><D><E><G><F><G><V><R><A><V><E><E><F><H><R><R><Y><A><V><P><D><N><V><T><I><L><D><G><G><T><Q><G><L><Y><L><V><N><Y><L><E><E><A><D><R><L><I><V><F><D><A><I><D><Y><G><L><E><P><G><R><L><K><L><V><R><D><D><E><V><P><R><F><T><G><A><K><K><M><S><L><H><Q><T><G><F><Q><E><V...
Not known. Could be involved in the processing of hydrogenase.<BOP>
Q45251
A3PBV7
DCUP_PROM0
Uroporphyrinogen decarboxylase
Prochlorococcus
<M><G><E><N><L><P><L><L><L><S><A><A><L><G><K><K><V><N><R><P><P><V><W><M><M><R><Q><A><G><R><Y><M><K><I><Y><R><D><L><R><E><R><Y><P><S><F><R><E><R><S><E><N><P><E><L><S><Y><E><I><S><M><Q><P><F><H><A><F><K><P><D><G><V><I><L><F><S><D><I><L><T><P><L><P><G><M><G><I><N><F><E><I><I><E><S><K><G><P><I><I><E><D><P><I><R><T><L><N><Q...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
A3PBV7
A8MG73
SYG_ALKOO
Glycyl-tRNA synthetase
Alkaliphilus
<M><A><T><E><K><T><M><E><K><I><V><S><L><A><K><S><R><G><F><I><F><P><G><S><E><I><Y><G><G><L><A><N><T><W><D><Y><G><P><L><G><V><E><L><K><N><N><V><K><K><A><W><W><K><K><F><I><Q><Q><S><P><Y><N><V><G><L><D><A><A><I><L><M><N><P><K><T><W><E><A><S><G><H><I><G><G><F><S><D><P><L><M><D><C><K><K><C><R><S><R><F><R><A><D><K><L><I><E><D...
Catalyzes the attachment of glycine to tRNA(Gly).<BOP>
A8MG73
B2S9M3
DER_BRUA1
GTP-binding protein EngA
Brucella
<M><G><F><T><L><A><I><V><G><R><P><N><V><G><K><S><T><L><F><N><R><L><V><G><R><K><L><A><L><V><D><D><L><P><G><V><T><R><D><R><R><I><H><D><A><K><L><Y><D><L><K><F><Q><V><I><D><T><A><G><L><E><E><A><A><N><D><S><L><E><A><R><M><R><A><Q><T><E><A><A><I><S><E><A><D><A><V><L><F><V><I><D><A><K><A><G><I><T><P><A><D><S><T><F><A><E><A><V...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
B2S9M3
Q8E3J2
RNH3_STRA3
Ribonuclease HIII
Streptococcus
<M><N><T><I><V><M><Q><A><D><K><K><L><Q><E><K><I><R><T><D><L><A><Q><H><H><I><S><N><N><N><P><Y><V><V><F><S><A><K><I><S><G><T><T><V><L><L><Y><T><S><G><K><L><V><F><Q><G><S><N><A><S><H><I><A><Q><K><Y><G><Y><I><E><Q><K><E><S><C><S><S><E><T><Q><D><I><P><I><I><G><T><D><E><V><G><N><G><S><Y><F><G><G><L><A><V><V><A><S><F><V><T><P...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q8E3J2
B3DTU8
NUCS_BIFLD
Endonuclease NucS
Bifidobacterium
<M><R><V><I><V><A><D><C><S><A><E><Y><S><G><R><L><N><A><S><L><P><L><A><K><R><V><L><L><I><K><A><D><S><S><L><L><I><F><S><E><L><G><S><Y><K><P><L><N><W><M><T><A><P><C><T><I><R><E><I><D><P><A><A><K><S><A><Q><H><S><R><E><S><V><A><G><G><A><V><D><G><D><S><A><T><H><S><P><E><S><V><A><A><G><E><P><E><K><V><L><R><V><S><A><D><K><G><S...
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.<BOP>
B3DTU8
Q38S26
COX2_ARVSO
Cytochrome c oxidase polypeptide II
Arvicanthis
<M><A><Y><P><F><Q><L><G><L><Q><D><A><T><S><P><I><M><E><E><L><T><N><F><H><D><H><T><L><M><I><V><F><L><I><S><S><L><V><L><Y><I><I><S><L><M><L><T><T><K><L><T><H><T><S><T><M><D><A><Q><E><V><E><T><I><W><T><I><L><P><A><A><I><L><I><L><I><A><L><P><S><L><R><I><L><Y><M><M><D><E><I><N><N><P><V><L><T><V><K><T><M><G><H><Q><W><Y><W><S...
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII...
Q38S26
Q8R070
G6PT2_MOUSE
Solute carrier family 37 member 1
Mus
<M><A><L><L><P><V><G><I><R><F><I><I><S><F><S><R><D><Q><W><Y><R><A><F><I><F><M><L><T><F><L><L><Y><A><S><F><H><L><S><R><K><P><I><S><I><V><K><G><E><L><H><K><Q><C><T><A><G><D><G><P><E><S><P><F><S><D><P><S><S><S><T><R><H><G><P><T><H><W><L><L><N><N><E><T><D><C><G><W><A><P><F><D><K><N><N><Y><Q><Q><L><L><G><A><L><D><Y><A><F><L...
Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucos...
Q8R070
Q0STU9
FABH_CLOPS
3-oxoacyl-[acyl-carrier-protein] synthase III
Clostridium
<M><E><N><A><K><I><I><G><F><G><L><Y><T><P><K><N><L><V><E><N><E><R><L><Q><E><F><L><E><T><S><D><E><W><I><R><S><R><T><G><I><E><R><R><Y><I><S><L><D><E><N><T><S><D><L><A><V><E><A><S><K><K><A><L><N><Q><A><G><L><S><A><E><E><I><D><L><I><I><V><A><T><V><T><P><D><N><F><T><P><S><T><A><C><I><V><Q><D><K><L><G><A><K><N><A><W><A><F><D...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A...
Q0STU9
B0JQ94
RL9_MICAN
50S ribosomal protein L9
Microcystis
<M><A><K><R><M><Q><V><I><L><N><Q><K><V><S><K><L><G><E><N><G><D><V><V><E><V><A><P><G><Y><A><R><N><Y><L><I><P><Q><G><V><A><V><L><A><T><K><G><A><I><K><Q><A><E><F><R><K><E><K><E><R><Q><R><L><L><A><E><K><Q><E><A><E><T><R><K><T><A><I><E><K><L><S><P><Y><S><I><P><K><Q><V><G><E><N><E><A><I><F><G><T><V><T><S><Q><D><V><A><T><V><I...
Binds to the 23S rRNA.<BOP>
B0JQ94
Q3ZC07
ACTC_BOVIN
Actin, alpha cardiac muscle 1, intermediate form
Bos
<M><C><D><D><E><E><T><T><A><L><V><C><D><N><G><S><G><L><V><K><A><G><F><A><G><D><D><A><P><R><A><V><F><P><S><I><V><G><R><P><R><H><Q><G><V><M><V><G><M><G><Q><K><D><S><Y><V><G><D><E><A><Q><S><K><R><G><I><L><T><L><K><Y><P><I><E><H><G><I><I><T><N><W><D><D><M><E><K><I><W><H><H><T><F><Y><N><E><L><R><V><A><P><E><E><H><P><T><L><L...
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.<BOP>
Q3ZC07
A9JRD8
BTB6A_DANRE
BTB/POZ domain-containing protein 6-A
Danio
<M><P><A><A><P><E><C><R><L><S><N><H><G><R><I><M><K><C><V><T><F><L><L><L><L><P><E><T><L><K><K><L><K><R><A><S><K><H><P><G><R><L><S><V><C><Y><N><I><L><T><L><S><L><K><K><R><M><A><A><E><L><Y><P><V><S><D><H><A><T><L><Q><K><S><G><A><V><M><L><S><L><P><E><K><K><R><N><V><E><P><V><S><Q><T><T><A><S><I><A><T><T><P><T><T><E><Q><N><I...
Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis.<BOP>
A9JRD8
A2BUK4
AROC_PROM5
5-enolpyruvylshikimate-3-phosphate phospholyase
Prochlorococcus
<M><S><S><I><F><G><K><I><F><R><V><S><T><F><G><E><S><H><G><G><A><V><G><V><I><L><D><G><C><P><P><K><L><K><I><N><I><D><L><I><Q><N><E><L><D><R><R><R><P><G><Q><S><K><I><T><T><P><R><K><E><D><D><K><L><E><I><L><S><G><L><K><E><G><I><T><L><G><T><P><I><A><M><L><V><R><N><K><D><Q><R><P><E><D><Y><N><N><L><E><Q><V><F><R><P><S><H><A><D...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
A2BUK4
Q5PCX2
AROC_SALPA
5-enolpyruvylshikimate-3-phosphate phospholyase
Salmonella
<M><A><G><N><T><I><G><Q><L><F><R><V><T><T><F><G><E><S><H><G><L><A><L><G><C><I><V><D><G><V><P><P><G><I><P><L><T><E><A><D><L><Q><H><D><L><D><R><R><R><P><G><T><S><R><Y><T><T><Q><R><R><E><P><D><Q><V><K><I><L><S><G><V><F><D><G><V><T><T><G><T><S><I><G><L><L><I><E><N><T><D><Q><R><S><Q><D><Y><S><A><I><K><D><V><F><R><P><G><H><A...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
Q5PCX2
B1ZFQ8
RS6_METPB
30S ribosomal protein S6
Methylorubrum
<M><P><L><Y><E><H><V><F><L><A><R><Q><D><V><T><A><Q><Q><V><E><T><M><V><E><T><Y><K><G><V><I><E><T><G><G><G><T><I><E><K><I><E><S><W><G><V><K><S><L><A><Y><R><I><K><K><N><R><K><A><H><F><T><L><L><N><I><S><A><P><P><A><A><L><A><E><M><E><R><Q><M><Q><I><S><E><D><V><L><R><F><M><T><V><R><V><E><Q><L><E><A><E><P><S><A><M><M><Q><K><R...
Binds together with S18 to 16S ribosomal RNA.<BOP>
B1ZFQ8
Q3ALF6
HIS6_SYNSC
ImGP synthase subunit HisF
unclassified Synechococcus
<M><V><A><L><R><L><I><P><C><L><D><V><A><R><G><R><V><V><K><G><V><N><F><V><G><L><R><D><A><G><D><P><V><E><L><A><C><R><Y><S><R><A><G><A><D><E><L><V><F><L><D><I><A><A><S><H><E><G><R><G><T><L><I><D><M><V><R><R><T><A><E><S><V><T><I><P><F><T><V><G><G><G><I><S><T><V><E><G><I><T><E><L><L><R><A><G><A><D><K><V><S><L><N><S><S><A><V...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP>
Q3ALF6
Q0HM20
RLMC_SHESM
23S rRNA(m5U747)-methyltransferase
Shewanella
<M><S><T><L><V><Q><C><G><Y><F><E><R><G><Q><C><Q><S><C><R><H><I><K><L><P><M><A><Q><Q><L><A><A><K><T><Q><E><L><Q><Q><L><L><A><P><F><V><D><N><A><E><P><Q><F><L><P><P><V><V><G><D><S><S><G><F><R><N><K><A><K><M><V><A><L><G><A><A><H><A><P><V><L><G><I><V><S><P><S><G><E><A><V><S><L><C><D><C><L><L><Y><P><A><D><M><Q><A><L><L><H><R...
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.<BOP>
Q0HM20
P04845
OMPA_SERMA
Outer membrane porin A
Serratia
<M><K><K><T><A><I><A><L><A><V><A><L><A><G><F><A><T><V><A><Q><A><A><P><K><D><N><T><W><Y><T><G><A><K><L><G><W><S><Q><Y><H><D><T><G><F><Y><G><N><G><Y><Q><N><G><I><G><N><G><P><T><H><K><D><Q><L><G><A><G><A><F><L><G><Y><Q><A><N><Q><Y><L><G><F><E><L><G><Y><D><W><L><G><R><M><P><Y><K><G><S><V><N><N><G><A><F><K><A><Q><G><V><Q><L...
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.<BOP>
P04845
Q5M869
SIT1_RAT
Suppression-inducing transmembrane adapter 1
Rattus
<M><S><R><E><N><N><C><T><T><A><D><L><A><W><G><I><P><S><I><T><Q><A><W><G><L><W><A><L><F><G><V><V><T><M><L><L><L><I><S><L><A><A><L><L><S><Q><W><T><R><G><R><R><R><T><Q><E><E><Q><G><P><P><S><G><R><S><V><E><E><V><P><L><Y><G><N><L><H><Y><L><Q><T><G><R><L><S><E><E><S><R><S><E><E><Q><D><P><S><S><G><G><L><A><R><G><A><E><E><A><T...
Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.<BOP>
Q5M869
Q6MSM5
RS10_MYCMS
30S ribosomal protein S10
Mycoplasma
<M><A><E><S><K><M><R><I><K><L><K><G><Y><D><H><A><I><V><D><Q><S><I><V><K><I><I><Q><A><A><E><G><T><G><A><K><V><R><G><P><I><P><L><P><T><E><K><Q><V><I><T><I><L><R><A><V><H><K><Y><K><D><S><R><E><Q><F><D><M><R><T><H><K><R><L><L><E><I><L><N><P><T><A><A><T><M><D><I><L><K><R><V><Q><L><P><S><G><V><D><I><E><I><K><L>
Involved in the binding of tRNA to the ribosomes.<BOP>
Q6MSM5
Q2S2F9
MIAA_SALRD
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Salinibacter
<M><E><P><L><S><E><P><D><A><S><D><P><I><L><T><I><T><G><P><T><A><V><G><K><T><A><V><S><L><E><A><A><E><Q><L><N><A><E><I><V><S><V><D><S><R><Q><V><Y><E><E><L><T><I><G><T><A><K><P><S><P><S><E><Q><R><R><A><P><H><H><F><I><G><E><R><S><L><H><E><P><F><S><A><G><A><Y><A><K><A><A><N><D><R><I><R><A><V><L><E><R><G><R><R><P><L><V><V><G...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
Q2S2F9
Q0RRS9
RPOC_FRAAA
Transcriptase subunit beta'
Frankia
<M><L><D><V><N><F><F><D><E><L><R><I><G><L><A><T><A><D><D><I><R><Q><W><S><H><G><E><V><K><K><P><E><T><I><N><Y><R><T><L><K><P><E><K><D><G><L><F><C><E><K><I><F><G><P><T><R><D><W><E><C><Y><C><G><K><Y><K><R><V><R><F><K><G><I><I><C><E><R><C><G><V><E><V><T><R><A><K><V><R><R><E><R><M><G><H><I><E><L><A><A><P><V><T><H><I><W><Y><F...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q0RRS9
P48633
HMWP2_YERE8
High-molecular-weight protein 2
Yersinia
<M><I><S><G><A><P><S><K><D><S><L><L><P><D><N><R><H><A><A><D><Y><Q><Q><L><R><E><R><L><I><Q><E><L><N><L><T><P><Q><Q><L><H><D><E><S><N><L><I><Q><A><G><L><D><S><I><R><L><M><R><W><L><H><W><F><R><K><N><G><Y><R><L><T><L><R><E><L><Y><A><A><P><T><L><A><A><W><N><Q><L><M><L><S><R><S><P><E><N><A><E><E><E><T><L><P><D><E><S><S><W><P...
Unknown. May be involved in the nonribosomal synthesis of small peptides.<BOP>
P48633
P0C1N8
M3B_CONTE
Tx3.3
Cylinder
<M><S><K><L><G><A><L><L><T><I><C><L><L><L><F><S><L><T><A><V><P><L><D><G><D><Q><H><A><D><Q><P><A><Q><R><L><Q><D><R><I><P><T><E><D><H><P><L><F><D><P><N><K><R><C><C><P><P><V><A><C><N><M><G><C><K><P><C><C><G>
Intracranial injection into mice causes scratching, hyperactivity and circular motion.<BOP>
P0C1N8
A9M752
MASZ_BRUC2
Malate synthase G
Brucella
<M><G><S><A><E><K><R><N><Y><V><E><I><E><G><L><A><V><A><P><E><L><V><E><F><L><A><K><E><A><A><P><G><T><G><V><E><P><E><K><F><W><K><G><F><A><A><I><I><R><D><L><A><P><K><N><R><A><L><L><A><K><R><D><E><L><Q><A><R><I><D><A><W><Y><K><E><N><R><D><K><G><Y><S><Q><A><D><Y><Q><Q><F><L><K><D><I><G><Y><L><L><P><E><G><G><A><F><S><V><S><T...
Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.<BOP>
A9M752
O50143
ATPE_RUMA7
F-ATPase epsilon subunit
Ruminococcus
<M><A><V><F><K><L><R><V><L><T><P><E><K><I><F><F><E><G><D><A><E><Q><L><I><A><K><T><T><S><G><Y><V><G><I><L><K><G><H><A><P><Y><V><A><S><I><V><P><S><E><M><K><I><R><S><D><G><S><F><R><S><A><A><I><S><D><G><I><V><K><V><S><E><D><S><M><V><T><V><L><T><S><A><I><E><W><S><D><E><I><D><V><A><R><A><E><R><S><K><A><R><A><E><K><Q><L><K><A...
Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP>
O50143
Q5RAY7
CMTR2_PONAB
FtsJ methyltransferase domain-containing protein 1
Pongo
<M><S><K><C><R><K><T><P><V><Q><Q><L><A><S><P><T><S><F><S><P><D><I><L><A><D><I><F><E><L><F><A><K><N><F><S><Y><S><K><P><L><N><N><E><W><Q><L><P><D><P><S><E><I><F><T><C><D><H><T><E><F><N><A><F><L><D><L><K><N><S><L><N><E><V><K><N><L><L><S><D><K><K><L><D><E><W><H><E><H><T><A><F><T><N><K><A><G><K><I><I><S><H><V><R><K><S><V><N...
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independ...
Q5RAY7
Q8YWF0
MURE_NOSS1
UDP-N-acetylmuramyl-tripeptide synthetase
Nostoc
<M><K><L><R><E><L><L><A><T><V><D><S><V><E><N><L><P><P><V><L><A><D><A><E><V><K><G><I><K><T><N><S><H><A><C><G><A><G><D><L><F><I><G><M><P><G><T><R><V><D><G><G><E><F><W><P><S><A><I><A><S><G><A><I><A><A><I><V><S><P><Q><A><V><E><K><N><P><P><H><D><E><A><V><V><I><S><S><N><N><M><T><K><A><C><A><A><I><A><A><A><F><Y><G><Y><P><G><Q...
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.<BOP>
Q8YWF0
Q49406
EX53_MYCGE
5'-3' exonuclease
Mycoplasma
<M><K><K><A><I><L><I><D><G><N><S><L><A><Y><R><A><Y><F><A><T><W><K><Q><V><E><Y><A><K><Q><N><N><L><P><F><N><N><A><I><R><T><M><L><L><M><C><W><N><L><I><K><A><N><V><Y><Q><Y><G><I><V><S><F><D><T><K><A><P><T><F><R><D><Q><I><Y><E><G><Y><K><Q><K><R><V><K><T><P><V><E><L><L><V><Q><I><P><L><I><K><Q><A><L><V><Y><L><G><F><L><V><C><E...
5'-3' exonuclease acting preferentially on double-stranded DNA.<BOP>
Q49406
Q82ZQ1
ALLB_ENTFA
Allantoin-utilizing enzyme
Enterococcus
<M><Q><A><E><L><V><I><K><N><G><L><V><I><L><E><T><G><E><V><I><T><D><V><A><V><Q><G><G><K><I><V><A><I><G><Q><D><L><S><G><E><R><V><I><D><A><T><G><L><V><V><S><P><G><M><V><D><A><H><V><H><I><T><D><P><G><G><G><Y><R><D><E><W><E><G><Y><V><T><G><T><A><A><C><A><K><G><G><V><T><T><F><M><E><M><P><L><N><Q><I><P><A><T><V><D><K><T><S><L...
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.<BOP>
Q82ZQ1
C6E105
RS20_GEOSM
30S ribosomal protein S20
unclassified Geobacter
<M><A><N><H><K><S><A><M><K><R><I><K><Q><T><A><K><R><T><E><R><N><K><H><E><R><S><T><L><R><T><F><I><K><R><V><R><E><A><V><A><T><K><D><Q><E><A><A><K><A><A><L><A><V><A><I><P><V><I><D><G><A><A><T><K><G><I><I><H><S><S><N><A><S><R><N><V><S><R><L><T><K><L><V><N><T><L><G>
Binds directly to 16S ribosomal RNA.<BOP>
C6E105
Q57457
LPTE_HAEIN
LPS-assembly lipoprotein LptE
Haemophilus
<M><I><N><S><I><K><T><L><L><L><I><A><T><L><A><I><L><S><A><C><G><W><H><F><Q><Q><S><V><T><M><P><S><E><W><R><T><L><A><L><E><S><D><D><S><Y><N><D><F><T><V><I><M><R><R><K><L><Q><E><N><Q><V><N><V><V><N><L><E><Q><N><I><P><I><L><R><I><N><K><Q><I><T><S><D><Q><V><A><S><I><F><K><H><G><R><E><A><E><K><L><L><M><L><E><V><E><A><T><F><R...
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.<BOP>
Q57457
A4XLQ7
IF1_CALS8
Translation initiation factor IF-1
Caldicellulosiruptor
<M><S><K><E><D><V><I><E><L><E><G><T><V><I><E><A><L><P><N><A><M><F><Q><V><Q><L><D><N><G><H><K><V><L><A><H><V><S><G><K><L><R><M><N><F><I><R><I><L><P><G><D><R><V><V><V><Q><L><S><P><Y><D><L><T><R><G><R><I><V><W><R><S><K>
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-...
A4XLQ7
Q9M815
PCR8_ARATH
Protein PLANT CADMIUM RESISTANCE 8
Arabidopsis
<M><G><R><V><T><T><P><S><E><E><D><S><N><N><G><L><P><V><Q><Q><P><G><T><P><N><Q><R><T><R><V><P><V><S><Q><F><A><P><P><N><Y><Q><Q><A><N><V><N><L><S><V><G><R><P><W><S><T><G><L><F><D><C><Q><A><D><Q><A><N><A><V><L><T><T><I><V><P><C><V><T><F><G><Q><I><A><E><V><M><D><E><G><E><M><T><C><P><L><G><T><F><M><Y><L><L><M><M><P><A><L><C...
May be involved in heavy metals transport.<BOP>
Q9M815
P08319
ADH4_HUMAN
Alcohol dehydrogenase class II pi chain
Homo
<M><G><T><K><G><K><V><I><K><C><K><A><A><I><A><W><E><A><G><K><P><L><C><I><E><E><V><E><V><A><P><P><K><A><H><E><V><R><I><Q><I><I><A><T><S><L><C><H><T><D><A><T><V><I><D><S><K><F><E><G><L><A><F><P><V><I><V><G><H><E><A><A><G><I><V><E><S><I><G><P><G><V><T><N><V><K><P><G><D><K><V><I><P><L><Y><A><P><L><C><R><K><C><K><F><C><L><S...
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol . Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate . Also catalyzes the reduc...
P08319
A0A0H2VFI8
ETTA_ECOL6
Translational regulatory factor EttA
Escherichia
<M><A><Q><F><V><Y><T><M><H><R><V><G><K><V><V><P><P><K><R><H><I><L><K><N><I><S><L><S><F><F><P><G><A><K><I><G><V><L><G><L><N><G><A><G><K><S><T><L><L><R><I><M><A><G><I><D><K><D><I><E><G><E><A><R><P><Q><P><D><I><K><I><G><Y><L><P><Q><E><P><Q><L><N><P><E><H><T><V><R><E><S><I><E><E><A><V><S><E><V><V><N><A><L><K><R><L><D><E><V...
A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during su...
A0A0H2VFI8
Q9UTE3
SEB1_SCHPO
Rpb7-binding protein seb1
Schizosaccharomyces
<M><S><G><I><A><E><F><D><G><I><L><D><S><L><E><H><S><K><T><G><I><S><G><S><K><I><L><K><L><T><N><L><S><M><E><N><V><S><E><N><A><Q><F><V><A><S><V><Y><K><Y><A><K><R><A><P><V><T><H><K><L><G><A><L><Y><I><L><D><S><I><V><R><S><F><Q><D><G><A><K><K><N><N><E><S><F><E><N><P><V><D><A><S><F><S><G><G><W><C><K><A><A><E><I><T><D><S><L><V...
Involved in the processing of pol II transcripts.<BOP>
Q9UTE3
Q8VCL2
SCO2_MOUSE
Protein SCO2 homolog, mitochondrial
Mus
<M><L><L><A><L><G><P><K><A><W><P><K><L><S><Q><F><K><P><L><L><R><I><S><G><G><E><T><L><H><R><N><S><R><H><W><A><G><Q><G><Q><R><Q><G><P><G><L><R><T><R><L><L><I><T><A><L><F><G><A><G><L><G><W><A><W><L><A><A><R><A><E><K><E><Q><W><R><Q><Q><Q><R><T><E><A><L><R><Q><A><A><V><G><Q><G><D><F><S><L><L><D><H><K><G><Q><P><R><C><K><A><D...
Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.<BOP>
Q8VCL2
P35304
HSP1_CAVPO
Cysteine-rich protamine
Cavia
<M><A><R><Y><R><C><C><R><S><P><S><R><S><R><C><R><R><R><R><R><R><F><Y><R><R><R><R><R><C><H><R><R><R><R><R><C><C><R><R><R><Y><T><R><R><C><K><R><Y>
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.<BOP>
P35304
Q08831
VTS1_YEAST
VTI1-2 suppressor protein 1
Saccharomyces
<M><K><H><P><Y><E><E><F><P><T><G><S><K><S><P><Y><N><M><S><R><G><A><H><P><G><A><V><L><L><S><P><Q><S><S><A><I><N><K><N><N><P><G><S><N><S><G><N><N><Q><G><N><S><S><V><T><A><N><V><L><S><P><Q><S><H><S><M><S><L><N><D><M><L><D><Q><Q><S><F><M><L><D><T><A><G><T><R><A><Q><P><L><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><A><S><L><P><S><L...
RNA-binding protein involved in post-transcriptional regulation through transcript degradation of SRE (SMG-recognition elements) bearing mRNAs.<BOP>
Q08831
Q8E3P5
GATB_STRA3
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Streptococcus
<M><N><F><E><T><V><I><G><L><E><V><H><V><E><L><N><T><N><S><K><I><F><S><P><S><S><A><H><F><G><Q><E><Q><N><A><N><T><N><V><I><D><W><S><F><P><G><V><L><P><V><M><N><K><G><V><V><D><A><G><I><K><A><A><L><A><L><N><M><D><I><H><Q><N><M><H><F><D><R><K><N><Y><F><Y><P><D><N><P><K><A><Y><Q><I><S><Q><F><D><E><P><I><G><Y><N><G><W><I><E><I...
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ...
Q8E3P5
Q8RQQ0
NPHA1_RHOSO
Two-component 4-nitrophenol hydroxylase
Rhodococcus
<M><T><T><S><A><F><V><D><D><R><V><G><V><P><N><D><V><R><P><M><T><G><D><E><Y><L><E><S><L><R><D><G><R><E><V><Y><F><R><G><E><R><V><D><D><V><T><T><H><P><A><F><R><N><S><A><R><S><V><A><R><M><Y><D><A><L><H><Q><P><E><Q><E><G><V><L><A><V><P><T><D><T><G><N><G><G><F><T><H><P><F><F><K><T><A><R><S><A><D><D><L><V><L><S><R><D><A><I><V...
Utilizes the flavins supplied by NphA2 to catalyze the degradation of 4-nitrophenol (4-NP) via 4-nitrocatechol (4-NC) which is used as the sole carbon, nitrogen, and energy source. Can also degrade phenol and 4-chlorophenol as rapidly as 4-NP.<BOP>
Q8RQQ0
A1EA34
PSBB_AGRST
Protein CP-47
Agrostis
<M><G><L><P><W><Y><R><V><H><T><V><V><L><N><D><P><G><R><L><L><A><V><H><I><M><H><T><A><L><V><S><G><W><A><G><S><M><A><L><Y><E><L><A><V><F><D><P><S><D><P><V><L><D><P><M><W><R><Q><G><M><F><V><I><P><F><M><T><R><L><G><I><T><D><S><W><G><G><W><S><I><S><G><G><T><V><T><N><P><G><I><W><S><Y><E><G><V><A><G><A><H><I><V><F><S><G><L><C...
One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient sub...
A1EA34
Q68XE1
PARE_RICTY
Topoisomerase IV subunit B
typhus group
<M><S><D><L><F><S><F><N><N><K><E><K><K><N><K><I><I><Y><T><N><Y><S><A><K><D><I><E><V><L><D><G><L><E><P><V><R><K><R><P><G><M><Y><I><G><G><T><D><S><N><A><M><H><H><L><V><S><E><V><L><D><N><A><M><D><E><A><V><A><G><F><A><S><I><I><M><I><K><M><H><Q><D><H><S><I><T><I><F><D><N><G><R><G><I><P><I><D><N><H><P><K><F><P><N><K><S><A><L...
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<BOP>
Q68XE1
Q6GEV0
ALF2_STAAR
Fructose-1,6-bisphosphate aldolase
Staphylococcus
<M><P><L><V><S><M><K><E><M><L><I><D><A><K><E><N><G><Y><A><V><G><Q><Y><N><I><N><N><L><E><F><T><Q><A><I><L><E><A><S><Q><E><E><N><A><P><V><I><L><G><V><S><E><G><A><A><R><Y><M><S><G><F><Y><T><I><V><K><M><V><E><G><L><M><H><D><L><N><I><T><I><P><V><A><I><H><L><D><H><G><S><S><F><E><K><C><K><E><A><I><D><A><G><F><T><S><V><M><I><D...
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.<BOP>
Q6GEV0
A8GMX9
TOLB_RICAH
Tol-Pal system protein TolB
spotted fever group
<M><R><N><I><I><Y><F><I><L><L><L><L><F><S><F><K><G><Y><A><L><E><T><I><N><I><E><H><G><Q><A><A><P><T><P><I><A><V><N><K><F><N><I><D><S><S><A><D><Y><V><L><G><N><D><V><V><K><V><I><S><N><D><L><K><L><S><G><V><F><C><P><I><S><S><A><S><F><I><E><E><R><T><G><I><E><Y><K><P><L><F><A><A><W><R><Q><I><N><A><S><L><L><V><N><G><E><I><K><K...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
A8GMX9
A6T306
HSLV_JANMA
ATP-dependent protease subunit HslV
Janthinobacterium
<M><E><Q><F><H><G><T><T><I><L><S><V><R><R><G><N><I><V><A><L><G><G><D><G><Q><V><T><L><G><N><I><V><M><K><G><T><A><R><K><V><R><K><V><Y><N><G><K><V><L><V><G><F><A><G><G><T><A><D><A><F><T><L><L><E><R><F><E><S><K><L><E><K><H><Q><G><H><L><M><R><A><S><V><E><L><A><K><D><W><R><T><D><R><M><L><R><R><L><E><A><M><L><L><V><A><D><K><E...
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.<BOP>
A6T306
Q0AD66
FPG_NITEC
DNA-(apurinic or apyrimidinic site) lyase MutM
Nitrosomonas
<M><P><E><L><P><E><V><E><V><T><R><R><G><I><D><A><H><L><A><G><R><Y><I><T><Q><V><K><I><R><N><Y><A><L><R><W><P><V><S><P><E><L><I><T><L><L><P><G><Q><R><I><N><T><I><T><R><R><A><K><Y><L><L><F><A><C><S><K><G><T><L><I><I><H><L><G><M><S><G><S><L><R><V><L><P><V><S><T><P><S><L><L><H><D><H><F><E><L><W><L><D><N><E><K><M><L><R><F><R...
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. ...
Q0AD66
Q2JLR0
DAPF_SYNJB
PLP-independent amino acid racemase
unclassified Synechococcus
<M><T><P><R><L><S><F><H><K><Y><Q><G><L><G><N><D><F><I><L><V><D><N><R><W><Q><S><Q><P><C><L><S><P><E><E><A><V><A><L><C><N><R><R><F><G><V><G><A><D><G><V><I><F><L><L><P><G><Q><E><G><A><D><F><S><M><R><L><F><N><S><D><G><S><E><A><E><M><C><G><N><G><I><R><C><L><A><R><F><L><Q><D><L><G><I><P><G><R><D><G><A><Y><Q><I><H><T><L><A><G...
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP>
Q2JLR0
Q6DIP3
RN126_XENTR
RING finger protein 126
Silurana
<M><A><E><A><L><P><E><A><G><R><Y><F><C><H><S><C><T><A><E><I><I><P><R><L><P><E><Y><T><C><P><R><C><D><S><G><F><I><E><E><L><P><E><T><R><N><S><E><N><N><S><S><N><N><S><G><T><D><Q><N><R><P><S><F><E><N><L><E><S><A><Q><F><T><L><P><S><G><Y><G><Q><V><T><F><G><I><F><N><E><G><L><D><F><P><I><F><G><T><S><G><P><V><E><E><P><R><D><G><E...
E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytos...
Q6DIP3
Q25145
TPM_HALRU
Tropomyosin
Haliotis
<M><D><A><I><K><K><K><M><L><A><M><K><M><E><K><E><N><A><V><D><R><A><E><Q><N><E><Q><K><L><R><D><T><E><E><Q><K><A><K><I><E><E><D><L><N><N><L><Q><K><K><C><A><N><L><E><N><D><F><D><S><V><N><E><Q><V><Q><V><A><M><A><K><L><E><T><S><E><K><R><V><T><E><M><E><Q><E><V><S><G><T><T><R><K><I><T><L><L><E><E><D><L><E><R><N><E><E><R><L><Q...
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.<BOP>
Q25145
O15287
FANCG_HUMAN
DNA repair protein XRCC9
Homo
<M><S><R><Q><T><T><S><V><G><S><S><C><L><D><L><W><R><E><K><N><D><R><L><V><R><Q><A><K><V><A><Q><N><S><G><L><T><L><R><R><Q><Q><L><A><Q><D><A><L><E><G><L><R><G><L><L><H><S><L><Q><G><L><P><A><A><V><P><V><L><P><L><E><L><T><V><T><C><N><F><I><I><L><R><A><S><L><A><Q><G><F><T><E><D><Q><A><Q><D><I><Q><R><S><L><E><R><V><L><E><T><Q...
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.<BOP>
O15287
Q8CN17
RBSD_STAES
D-ribose pyranase
Staphylococcus
<M><K><K><T><A><V><L><N><S><H><I><S><S><A><I><S><T><L><G><H><Y><D><L><L><T><I><N><D><A><G><M><P><I><P><N><D><D><K><R><I><D><L><A><V><T><K><S><L><P><R><F><I><D><V><L><E><T><V><L><T><E><M><E><I><Q><K><V><Y><L><A><E><E><I><K><T><A><N><A><Q><Q><L><K><A><I><K><K><L><I><N><D><D><V><E><I><K><F><I><A><H><S><E><M><K><E><M><L><K...
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.<BOP>
Q8CN17