accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
P29566
T2MZ_METTF
Type-2 restriction enzyme MthZI
Methanothermobacter
<M><I><D><N><F><K><E><I><R><L><D><F><K><D><E><L><K><K><I><T><G><K><E><V><E><F><P><K><Y><T><T><Q><I><I><N><L><A><N><Q><N><A><Q><G><T><R><P><R><V><V><G><Q><M><S><D><L><I><H><E><C><P><D><K><S><Y><E><G><W><K><K><W><Y><L><E><H><Y><S><D><R><I><E><K><A><T><K><K><I><S><K><M><I><E><N><M><K><A><A><M><E><L><I><D><E><E><M><I><R><K...
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTAG-3' and cleaves after C-1.<BOP>
P29566
Q8BS90
BORA_MOUSE
Protein aurora borealis
Mus
<M><G><D><V><S><E><L><K><M><Q><I><T><P><E><T><P><G><R><I><P><V><L><N><P><F><E><S><P><S><D><Y><S><N><L><H><E><Q><T><L><A><S><P><S><I><F><K><S><T><K><L><P><T><P><G><K><F><R><W><S><I><D><Q><L><A><I><I><N><P><V><E><I><D><P><E><E><I><H><R><Q><A><S><Y><L><R><L><S><R><I><D><K><D><V><E><D><K><R><Q><K><A><I><E><E><F><F><T><K><D...
Required for the activation of AURKA at the onset of mitosis.<BOP>
Q8BS90
Q12CI6
TYSY_POLSJ
Thymidylate synthase
unclassified Polaromonas
<M><N><T><P><P><E><T><R><P><D><R><P><I><R><S><Q><Y><E><D><F><M><R><H><V><D><A><H><G><V><F><K><A><D><R><T><G><T><G><T><K><S><V><F><G><Y><Q><M><R><F><D><L><N><E><G><F><P><L><V><T><T><K><K><V><H><L><K><S><I><V><Q><E><L><L><W><F><L><T><G><S><S><D><N><N><W><L><K><E><R><G><V><T><I><W><D><E><W><A><R><E><D><G><D><L><G><P><V><Y...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
Q12CI6
Q8W4E2
VATB3_ARATH
Vacuolar proton pump subunit B3
Arabidopsis
<M><V><E><T><S><I><D><M><E><E><G><T><L><E><I><G><M><E><Y><R><T><V><S><G><V><A><G><P><L><V><I><L><D><K><V><K><G><P><K><Y><Q><E><I><V><N><I><R><L><G><D><G><S><T><R><R><G><Q><V><L><E><V><D><G><E><K><A><V><V><Q><V><F><E><G><T><S><G><I><D><N><K><F><T><T><V><Q><F><T><G><E><V><L><K><T><P><V><S><L><D><M><L><G><R><I><F><N><G><S...
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.<BOP>
Q8W4E2
J9VME1
AFR1_CRYNH
ABC multidrug transporter AFR1
Cryptococcus neoformans species complex
<M><S><A><A><G><V><P><A><E><L><N><N><L><G><A><P><I><T><A><T><T><Q><N><P><S><G><L><A><N><S><Q><V><T><S><G><P><V><S><S><A><T><Q><H><D><E><H><R><S><S><A><G><N><T><L><A><D><E><E><D><D><K><A><V><E><A><E><K><A><E><A><I><D><A><A><G><D><G><K><Q><K><R><L><P><A><D><S><S><E><D><I><V><A><E><L><E><P><H><H><V><S><V><H><R><G><K><E><E...
Major pleiotropic ABC efflux transporter that confers resistance to structurally and functionally unrelated compounds including azoles such as fluconazole (FLC), itraconazole (ITC), posaconazole (POS), and voriconazole (VRC) . Is also able to efflux the eukaryote protein synthesis inhibitor cycloheximide (CHX) .<BOP>
J9VME1
B2IYW1
MUTL_NOSP7
DNA mismatch repair protein MutL
Nostoc
<M><A><S><I><I><Q><A><L><P><T><E><V><V><Y><L><I><T><A><G><E><V><I><D><S><L><A><S><V><V><R><E><L><V><E><N><S><L><D><A><G><A><T><R><I><V><V><S><L><W><P><Q><Q><W><R><I><R><V><A><D><N><G><C><G><M><N><L><D><D><L><Q><Q><A><A><T><A><H><S><T><S><K><I><R><S><S><A><D><L><W><K><I><N><S><L><G><F><R><G><E><A><L><H><S><L><T><T><L><A...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
B2IYW1
Q8C5S7
REC8_MOUSE
Cohesin Rec8p
Mus
<M><F><Y><Y><P><N><V><L><Q><R><H><T><G><C><F><A><T><I><W><L><A><A><T><R><G><S><R><L><V><K><R><E><Y><L><N><V><N><V><V><K><T><C><E><E><I><L><N><Y><V><L><V><R><V><Q><P><P><V><A><G><L><P><R><P><R><F><S><L><Y><L><S><A><Q><L><Q><I><G><V><I><R><V><Y><F><Q><Q><C><Q><Y><L><V><E><D><I><Q><H><I><L><E><H><L><H><R><A><Q><L><R><I><R...
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in m...
Q8C5S7
Q6LW55
YIDC_PHOPR
Membrane protein YidC
Photobacterium
<M><D><S><Q><R><N><I><L><L><I><A><L><L><F><V><S><F><L><L><Y><Q><Q><W><N><M><D><N><S><P><Q><P><Q><G><Q><G><T><E><Q><Q><V><N><N><S><G><D><V><P><S><H><S><G><D><G><Q><P><I><P><D><Q><E><T><T><S><K><D><L><I><T><I><N><T><D><V><L><A><L><S><V><D><T><L><G><G><D><V><I><E><A><K><L><L><A><Y><N><N><E><L><D><S><A><D><S><F><I><L><L><K...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb...
Q6LW55
Q8DH70
RECA_THEVB
Recombinase A
Thermosynechococcus
<M><S><D><T><T><L><S><L><L><S><P><E><K><R><K><A><L><E><F><A><I><S><Q><I><E><R><S><F><G><K><G><S><I><M><R><L><G><D><A><T><S><M><K><V><E><T><I><S><S><G><A><L><T><L><D><L><A><L><G><G><G><L><P><K><G><R><I><I><E><I><Y><G><P><E><S><S><G><K><T><T><L><A><L><H><A><I><A><E><V><Q><K><A><G><G><V><A><A><F><V><D><A><E><H><A><L><D><P...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
Q8DH70
A5F4G3
UBIB_VIBC3
Ubiquinone biosynthesis protein UbiB
Vibrio
<M><K><P><A><E><L><K><R><L><Y><R><I><V><K><V><Q><L><E><Y><G><L><D><E><L><L><P><E><H><H><L><T><R><A><P><L><L><A><R><K><S><L><F><W><L><R><N><Q><H><A><D><K><A><L><G><D><R><L><R><L><A><L><Q><E><L><G><P><V><W><I><K><F><G><Q><M><M><S><T><R><R><D><L><F><P><P><Y><I><A><D><P><L><A><M><L><Q><D><K><V><A><P><F><D><G><L><Q><A><K><Q...
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP>
A5F4G3
Q7M8K0
UVRC_WOLSU
Excinuclease ABC subunit C
Wolinella
<M><Q><S><E><T><L><L><E><T><L><Q><N><L><P><D><Q><S><G><V><Y><H><Y><F><D><S><R><S><K><L><L><Y><V><G><K><A><K><S><L><K><K><R><V><K><S><Y><F><Q><F><T><P><T><L><A><P><S><P><K><L><S><P><R><I><H><K><M><I><S><E><A><A><F><I><R><Y><I><V><V><E><N><E><H><D><A><L><I><L><E><N><S><L><I><K><Q><L><K><P><K><Y><N><I><L><L><R><D><D><K><T...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q7M8K0
Q98DV1
LEPA_RHILO
Ribosomal back-translocase LepA
Mesorhizobium
<M><S><T><P><L><D><H><I><R><N><F><S><I><V><A><H><I><D><H><G><K><S><T><L><A><D><R><L><I><Q><S><T><G><G><L><E><L><R><D><M><K><E><Q><V><L><D><S><M><D><I><E><R><E><R><G><I><T><I><K><A><Q><T><V><R><L><K><Y><R><A><N><N><G><E><D><Y><I><L><N><L><I><D><T><P><G><H><V><D><F><A><Y><E><V><S><R><S><L><A><A><C><E><G><S><L><L><V><V><D...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
Q98DV1
Q6G5P7
GLMM_BARHE
Phosphoglucosamine mutase
Bartonella
<M><P><Q><K><Y><F><G><T><D><G><I><R><G><K><A><N><V><F><P><M><T><P><D><F><A><M><K><V><G><M><A><V><G><I><L><F><R><S><Q><N><Q><S><R><R><V><V><I><G><K><D><T><R><L><S><G><Y><M><L><E><N><A><L><V><S><G><F><T><A><A><G><M><E><A><F><L><L><G><P><V><P><T><P><A><V><A><M><L><C><R><S><L><R><A><D><L><G><V><M><I><S><A><S><H><N><P><F><Y...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
Q6G5P7
Q6JB15
MEG1_MAIZE
Protein MATERNALLY EXPRESSED GENE 1
Zea
<M><E><Y><K><K><R><V><D><A><L><V><F><F><S><L><L><L><L><G><Y><F><A><A><H><A><H><G><N><G><H><V><T><D><D><V><N><V><S><A><P><A><E><E><G><I><L><R><E><K><R><A><Q><C><A><Q><G><F><L><P><C><K><D><N><K><C><Y><C><C><I><G><G><R><T><H><D><C><Y><Y><T><M><A><Q><C><S><H><A><C><F>
Regulates maternal nutrient uptake, sucrose partitioning, and seed biomass yield. Necessary and sufficient for the establishment and differentiation of the endosperm nutrient transfer cells located at the mother:seed interface. Exclusive expression of the maternal allele at the early stages of endosperm development. Th...
Q6JB15
B2VIN7
NUON_ERWT9
NDH-1 subunit N
Erwinia
<M><T><I><T><P><Q><Q><L><I><A><L><L><P><L><L><I><V><G><L><T><V><V><V><V><M><L><S><I><A><W><R><R><N><H><F><V><N><A><T><L><A><V><V><G><L><N><L><A><L><F><S><L><Y><F><V><G><Q><A><G><P><M><D><V><T><P><L><L><R><I><D><A><Y><S><M><F><Y><T><G><L><V><I><L><A><S><L><A><T><C><T><F><A><Y><P><W><L><A><T><Y><P><D><N><R><E><E><F><Y><L...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
B2VIN7
Q83HM3
SYT_TROW8
Threonyl-tRNA synthetase
Tropheryma
<M><D><G><F><E><F><F><S><G><R><S><D><V><V><A><M><I><C><D><D><R><L><L><D><L><S><E><S><I><P><S><G><K><V><P><E><P><I><E><L><D><S><P><R><G><L><D><I><L><R><H><S><C><A><H><V><L><A><Q><A><V><Q><S><I><Y><G><D><A><K><L><G><I><G><P><F><T><E><N><G><F><Y><Y><D><F><S><V><N><E><P><F><S><S><D><S><L><R><V><I><E><D><K><M><R><E><I><V><H...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
Q83HM3
A0QKZ8
RS8_MYCA1
30S ribosomal protein S8
Mycobacterium avium complex (MAC)
<M><T><M><T><D><P><I><A><D><F><L><T><R><L><R><N><A><N><S><A><Y><H><D><E><V><T><L><P><H><S><K><L><K><A><N><I><A><Q><I><L><K><N><E><G><Y><I><S><D><F><R><T><E><D><A><R><V><G><K><S><L><I><V><Q><L><K><Y><G><P><S><R><E><R><S><I><A><G><L><R><R><V><S><K><P><G><L><R><V><Y><A><K><S><T><N><L><P><R><V><L><G><G><L><G><V><A><I><I><S...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
A0QKZ8
Q52036
BPHD_PSEPU
2,6-dioxo-6-phenylhexa-3-enoate hydrolase
Pseudomonas
<M><T><A><L><T><E><S><S><T><S><K><F><L><N><I><K><E><K><G><L><S><D><F><K><I><H><Y><N><E><A><G><N><G><E><T><V><I><M><L><H><G><G><G><P><G><A><G><G><W><S><N><Y><Y><R><N><I><G><P><F><V><E><A><G><Y><R><V><I><L><K><D><S><P><G><F><N><K><S><D><A><V><V><M><D><E><Q><R><G><L><V><N><A><R><A><V><K><G><L><M><D><A><L><G><I><D><R><A><H...
Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD).<BOP>
Q52036
B2K948
NANE_YERPB
ManNAc-6-P epimerase
Yersinia
<M><S><N><L><S><N><L><R><H><K><L><Q><N><G><L><I><A><S><C><Q><P><V><P><G><S><A><M><D><T><P><E><I><V><A><A><M><A><C><A><A><L><A><G><G><A><V><G><L><R><I><E><G><I><S><N><I><Q><A><V><R><R><A><T><D><A><P><I><I><G><I><I><K><R><D><L><P><D><S><E><V><R><I><T><P><W><L><E><D><I><D><A><L><S><A><A><G><A><D><I><I><A><F><D><V><T><C><R...
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).<BOP>
B2K948
Q5AQE4
LIPA_EMENI
Lipoic acid synthase
Aspergillus subgen. Nidulantes
<M><A><A><A><T><N><R><F><R><A><L><Y><S><S><S><R><V><A><T><P><Q><A><G><S><A><S><Y><L><S><Y><R><G><Y><A><T><T><D><P><S><S><A><T><G><G><A><S><T><A><G><K><R><R><T><T><F><T><D><K><L><N><A><G><P><S><F><G><D><F><V><S><G><G><R><D><N><A><P><L><D><P><S><E><A><Y><A><L><K><T><A><L><V><G><P><A><G><R><K><K><E><M><T><R><L><P><S><W><L...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
Q5AQE4
Q95QD1
TM135_CAEEL
Transmembrane protein 135 homolog
Caenorhabditis
<M><G><A><L><S><K><L><A><H><S><L><G><Q><P><I><L><T><A><T><C><Y><E><T><I><H><T><W><N><P><D><C><N><G><A><F><F><D><A><L><P><V><G><L><I><F><S><L><K><T><Y><A><S><F><Y><L><I><T><N><V><V><S><K><R><G><R><L><D><K><I><N><W><K><K><F><G><I><D><V><C><Q><S><S><L><F><L><V><T><N><M><C><F><F><L><I><L><L><C><K><F><R><K><W><L><G><F><F><T...
Involved in fat storage.<BOP>
Q95QD1
Q8PPC9
KDPB_XANAC
Potassium-translocating ATPase B chain
Xanthomonas
<M><S><T><I><D><T><T><E><K><R><E><R><G><D><A><A><L><F><D><A><A><V><L><V><A><A><M><R><A><A><F><A><K><L><A><P><R><H><L><L><R><S><P><V><M><A><V><V><M><G><G><T><V><L><A><A><V><I><T><A><S><G><H><S><H><A><G><F><G><W><A><V><T><A><I><L><F><V><T><V><L><F><G><N><F><A><E><A><I><A><E><A><R><G><R><G><Q><A><A><S><L><R><R><A><R><K><D...
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.<BOP...
Q8PPC9
B8M9K3
TROPF_TALSN
Tropolone synthesis protein F
Talaromyces sect. Talaromyces
<M><L><H><G><M><S><P><E><C><A><L><S><K><L><L><S><S><L><E><F><H><T><L><Y><R><Y><T><M><T><Q><K><H><N><F><P><S><N><N><K><D><T><L><H><L><P><R><I><L><C><L><H><G><G><G><T><N><A><R><I><F><R><A><Q><C><R><A><L><E><K><A><L><R><T><S><F><R><L><C><Y><A><E><A><L><F><P><S><Q><P><G><P><D><V><T><A><V><Y><R><D><F><G><P><F><R><A><W><I><D...
Esterase; part of the gene cluster that mediates the biosynthesis of the tropolone class of fungal maleic anhydrides . The pathway begins with the synthesis of 3-methylorcinaldehyde by the non-reducing polyketide synthase (PKS) tropA . 3-methylorcinaldehyde is the substrate for the FAD-dependent monooxygenase tropB to ...
B8M9K3
B4RLK9
LIPA_NEIG2
Sulfur insertion protein LipA
Neisseria
<M><S><E><I><K><T><D><D><P><K><R><G><I><K><L><R><G><A><D><K><T><A><R><I><P><I><K><V><V><P><L><Q><E><K><L><K><K><P><E><W><I><R><A><K><L><P><S><R><K><F><F><E><I><K><D><I><L><R><E><Q><K><M><H><T><V><C><E><E><A><S><C><P><N><I><G><E><C><F><S><K><G><T><A><T><F><M><I><M><G><D><I><C><T><R><R><C><P><F><C><D><V><G><H><G><R><P><N...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
B4RLK9
Q7N8N7
LPXD_PHOLL
UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase
Photorhabdus
<M><S><S><I><R><L><A><D><L><A><Q><Q><L><N><A><Q><L><H><G><D><G><D><I><V><I><T><S><I><A><P><M><H><S><A><N><G><E><Q><I><T><F><L><S><D><S><R><Y><R><E><R><L><G><E><C><Q><A><A><A><V><V><L><Q><A><S><D><L><P><Y><C><N><I><P><A><L><V><V><A><N><P><Y><L><A><Y><A><Y><M><A><Q><I><M><D><T><T><P><I><P><A><Q><D><I><H><S><S><A><V><I><S...
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q7N8N7
B2U7X2
HSLV_RALPJ
ATP-dependent protease subunit HslV
Ralstonia
<M><E><Q><Y><H><G><T><T><I><V><S><V><R><R><G><N><Q><V><A><L><G><G><D><G><Q><V><T><L><G><N><I><V><M><K><G><S><A><R><K><V><R><A><I><Y><D><G><K><V><L><V><G><F><A><G><A><T><A><D><A><F><S><L><L><D><R><F><E><A><K><L><Q><K><H><Q><G><N><L><L><R><S><A><V><D><L><A><K><D><W><R><T><D><R><A><L><R><H><L><E><A><M><L><I><V><A><D><R><E...
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.<BOP>
B2U7X2
Q5PQQ6
DRC9_RAT
IQ domain-containing protein G
Rattus
<M><E><G><E><E><L><E><T><T><G><S><L><S><E><V><F><Q><P><E><V><T><M><A><V><T><G><E><P><P><K><P><A><E><E><E><L><E><E><E><E><E><E><T><S><P><E><V><I><D><T><L><S><L><L><D><V><L><R><V><S><A><I><M><E><D><I><I><D><Q><L><S><I><L><G><Y><I><I><P><V><Q><Y><E><R><R><Q><S><L><S><Q><K><T><S><H><E><G><A><P><M><V><P><S><T><P><K><I><S><A...
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation o...
Q5PQQ6
B0K5Q9
RL18_THEPX
50S ribosomal protein L18
unclassified Thermoanaerobacter
<M><I><T><K><P><N><R><N><E><L><R><K><R><R><H><L><R><V><R><K><K><V><F><G><T><P><E><R><P><R><L><N><V><F><R><S><L><K><H><I><Y><A><Q><I><I><D><D><T><K><G><H><T><L><V><H><A><S><T><L><D><P><E><L><R><G><I><A><K><G><A><N><K><Q><S><A><K><L><V><G><E><L><I><A><K><R><A><L><E><K><G><I><K><D><V><V><F><D><R><G><G><Y><I><Y><H><G><V><V...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
B0K5Q9
Q5F5J4
MUTS_NEIG1
DNA mismatch repair protein MutS
Neisseria
<M><S><K><S><A><V><S><P><M><M><Q><Q><Y><L><G><I><K><A><Q><H><T><D><K><L><V><F><Y><R><M><G><D><F><Y><E><L><F><L><D><D><A><V><E><A><A><K><L><L><D><I><T><L><T><T><R><G><Q><M><D><G><V><P><I><K><M><A><G><V><P><F><H><A><A><E><Q><Y><L><A><R><L><V><K><L><G><K><S><V><A><I><C><E><Q><V><G><E><V><G><A><G><K><G><P><V><E><R><K><V><V...
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.<BOP>
Q5F5J4
Q0C8J3
MANC_ASPTN
Endo-beta-1,4-mannanase C
Aspergillus subgen. Circumdati
<M><L><I><N><F><E><K><V><L><S><L><A><L><L><A><G><S><V><S><G><R><K><H><V><P><R><G><F><V><T><T><S><G><M><K><F><Q><L><D><G><K><D><F><Y><F><A><G><S><N><A><Y><Y><F><P><F><N><D><N><Q><T><D><V><E><L><G><L><A><A><A><K><Q><A><G><L><T><V><F><R><T><W><G><F><N><D><K><N><A><T><Y><I><E><G><G><L><P><A><Y><G><G><E><G><A><G><T><T><E><V...
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.<BOP>
Q0C8J3
Q2JWK3
PSBM_SYNJA
Photosystem II reaction center protein M
unclassified Synechococcus
<M><E><T><N><Y><L><G><L><L><A><T><I><L><V><I><L><V><P><S><I><F><L><V><I><L><Y><V><Q><T><S><S><K><S><E><S>
One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, a...
Q2JWK3
B5FFC4
ADD_ALIFM
Adenosine aminohydrolase
Aliivibrio
<M><I><I><K><Q><L><P><L><T><D><L><H><R><H><L><D><G><N><I><R><I><E><T><I><L><D><L><G><Q><K><F><G><L><D><L><P><A><Y><D><I><E><A><L><R><P><H><V><Q><I><V><E><A><E><P><S><L><V><A><F><L><S><K><L><D><W><G><V><A><V><L><G><D><L><D><A><C><R><R><V><A><Y><E><N><V><Q><D><A><M><N><A><Q><I><D><Y><A><E><L><R><F><S><P><Y><Y><M><A><M><K...
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.<BOP>
B5FFC4
Q08269
ALR1_YEAST
Aluminum resistance protein 1
Saccharomyces
<M><S><S><S><S><S><S><S><E><S><S><P><N><L><S><R><S><N><S><L><A><N><T><M><V><S><M><K><T><E><D><H><T><G><L><Y><D><H><R><Q><H><P><D><S><L><P><V><R><H><Q><P><P><T><L><K><N><K><E><I><A><K><S><T><K><P><S><I><P><K><E><Q><K><S><A><T><R><Y><N><S><H><V><D><V><G><S><V><P><S><R><G><R><M><D><F><E><D><E><G><Q><G><M><D><E><T><V><A><H...
Plasma membrane magnesium transporter.<BOP>
Q08269
P0C927
ASB14_RAT
Ankyrin repeat and SOCS box protein 14
Rattus
<M><D><Q><Q><S><S><D><E><D><A><D><T><D><F><D><T><Q><I><I><I><Q><Q><S><L><L><D><A><Y><K><P><E><L><T><G><R><T><P><E><D><E><R><S><Q><S><F><S><S><E><D><Y><K><K><I><V><E><A><I><E><T><V><K><Y><S><S><Y><P><R><P><S><K><E><D><A><L><A><S><F><A><K><Y><H><P><A><F><D><E><A><N><G><S><G><W><L><P><L><H><K><A><A><V><Q><L><N><K><N><I><L...
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP>
P0C927
A4YYT0
AHPD_BRASO
Alkylhydroperoxidase AhpD
unclassified Bradyrhizobium
<M><S><I><E><Q><L><K><D><Q><I><P><D><F><A><K><D><V><R><L><N><L><S><S><M><A><S><D><E><T><L><S><P><Q><A><K><Y><G><L><F><V><A><C><A><I><A><T><R><N><P><M><V><M><A><A><F><E><A><V><A><A><A><Q><L><S><A><T><A><L><A><A><A><K><S><A><A><A><I><M><A><M><N><N><V><Y><Y><R><F><V><H><L><A><S><N><K><E><Y><A><T><M><P><A><R><L><R><M><N><V...
Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.<BOP>
A4YYT0
Q9Z734
RIBBA_CHLPN
GTP cyclohydrolase II
Chlamydia
<M><I><E><T><R><E><E><V><G><S><A><N><F><V><S><L><E><R><A><I><E><D><L><R><A><G><K><F><V><I><V><V><D><E><A><S><R><E><D><E><G><D><L><I><I><A><G><E><K><I><T><V><E><K><M><T><F><L><L><Q><H><T><T><G><V><V><C><A><A><L><S><Q><E><R><L><L><S><L><D><L><P><P><M><V><K><D><N><R><C><R><F><K><T><P><F><T><V><S><V><D><A><A><H><G><V><T><T...
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.<BOP>
Q9Z734
B3EMN6
PNP_CHLPB
Polynucleotide phosphorylase
Chlorobium
<M><F><I><R><K><E><I><D><L><G><D><G><K><V><I><T><I><E><T><G><K><M><A><K><Q><A><D><G><A><T><I><V><R><M><G><D><T><M><V><I><A><T><V><V><S><S><R><T><P><P><S><P><N><Q><D><F><F><P><M><Q><V><E><Y><R><E><K><Y><Y><A><A><G><K><F><P><G><G><F><I><K><R><E><S><R><P><S><E><K><E><I><L><S><A><R><L><I><D><R><A><L><R><P><L><F><P><N><G><Y...
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP>
B3EMN6
Q9BIG2
GPA14_CAEEL
Guanine nucleotide-binding protein alpha-14 subunit
Caenorhabditis
<M><A><F><S><C><F><D><K><F><S><Y><T><Y><C><Y><Q><C><M><H><G><P><D><G><C><M><V><P><S><R><N><G><E><G><T><E><L><Y><A><H><S><E><E><L><E><A><K><L><R><E><L><A><R><R><G><H><M><E><I><E><K><E><L><A><L><E><K><K><T><Y><G><S><H><I><K><I><L><I><L><G><G><P><L><S><G><K><S><T><I><F><K><Q><M><Q><I><I><H><V><D><G><F><K><T><D><Q><E><L><I...
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In association with the G-protein coupled dopamine receptor dop-2, modulates two types of learning: touch habituation and chemosensory associative conditioning .<BOP>
Q9BIG2
C5BCH5
RISB_EDWI9
6,7-dimethyl-8-ribityllumazine synthase
Edwardsiella
<M><K><T><I><Q><G><V><V><A><A><P><Q><A><R><V><A><I><A><I><S><R><F><N><H><F><I><N><D><S><L><L><E><G><A><I><D><A><L><K><R><I><G><Q><V><S><D><E><N><I><T><V><V><W><V><P><G><A><Y><E><L><P><L><T><V><R><A><L><A><S><S><G><R><Y><D><A><V><V><A><L><G><T><V><I><R><G><G><T><A><H><F><E><F><V><A><G><E><C><S><S><G><L><A><S><V><A><L><N...
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP>
C5BCH5
A8FJZ3
CLPP_CAMJ8
Endopeptidase Clp
Campylobacter
<M><F><I><P><Y><V><I><E><K><S><S><R><G><E><R><S><Y><D><I><Y><S><R><L><L><K><D><R><I><I><M><L><S><G><E><I><H><D><E><L><A><A><S><I><V><A><Q><L><L><F><L><E><A><E><D><P><T><K><D><I><Y><L><Y><I><N><S><P><G><G><V><I><T><S><G><F><S><I><Y><D><T><M><N><Y><I><K><P><D><V><C><T><I><C><I><G><Q><A><A><S><M><G><A><F><L><L><S><C><G><A...
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.<BOP>
A8FJZ3
Q6FUI5
LCMT1_CANGA
[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1
Nakaseomyces/Candida clade
<M><E><L><A><V><Q><R><T><D><T><D><A><L><S><S><K><V><S><A><I><H><T><K><Y><L><S><G><G><I><S><Q><Q><F><A><Y><E><E><V><Y><G><E><Y><L><A><S><L><R><Q><V><S><R><R><V><F><G><K><C><R><Y><S><G><A><S><F><P><V><M><N><Y><G><T><Y><L><R><T><V><A><I><D><E><R><V><L><E><F><L><Q><C><N><S><G><S><Q><V><Q><I><V><N><I><G><C><G><S><D><L><R><M...
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.<BOP>
Q6FUI5
Q4JL84
MYB59_ARATH
Myb-related protein 59
Arabidopsis
<M><K><L><V><Q><E><E><Y><R><K><G><P><W><T><E><Q><E><D><I><L><L><V><N><F><V><H><L><F><G><D><R><R><W><D><F><V><A><K><V><S><G><L><N><R><T><G><K><S><C><R><L><R><W><V><N><Y><L><H><P><G><L><K><R><G><K><M><T><P><Q><E><E><R><L><V><L><E><L><H><A><K><W><G><N><R><W><S><K><I><A><R><K><L><P><G><R><T><D><N><E><I><K><N><Y><W><R><T><H...
Transcription factor.<BOP>
Q4JL84
P02602
MYL1_RABIT
Myosin light chain alkali 1/2
Oryctolagus
<M><A><P><K><K><D><V><K><K><P><A><A><A><A><A><P><A><P><A><P><A><P><A><P><A><P><A><P><A><K><P><K><E><E><K><I><D><L><S><A><I><K><I><E><F><S><K><E><Q><Q><D><E><F><K><E><A><F><L><L><Y><D><R><T><G><D><S><K><I><T><L><S><Q><V><G><D><V><L><R><A><L><G><T><N><P><T><N><A><E><V><K><K><V><L><G><N><P><S><N><E><E><M><N><A><K><K><I><E...
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.<BOP>
P02602
P05813
CRBA1_HUMAN
Beta-crystallin A3, isoform A1, Delta8 form
Homo
<M><E><T><Q><A><E><Q><Q><E><L><E><T><L><P><T><T><K><M><A><Q><T><N><P><T><P><G><S><L><G><P><W><K><I><T><I><Y><D><Q><E><N><F><Q><G><K><R><M><E><F><T><S><S><C><P><N><V><S><E><R><S><F><D><N><V><R><S><L><K><V><E><S><G><A><W><I><G><Y><E><H><T><S><F><C><G><Q><Q><F><I><L><E><R><G><E><Y><P><R><W><D><A><W><S><G><S><N><A><Y><H><I...
Crystallins are the dominant structural components of the vertebrate eye lens.<BOP>
P05813
B0CFX4
SYA_ACAM1
Alanyl-tRNA synthetase
Acaryochloris
<M><V><A><S><L><S><G><A><Q><I><R><Q><T><F><L><D><F><Y><A><A><K><G><H><K><I><L><P><S><A><S><L><V><P><E><D><P><T><V><L><L><T><I><A><G><M><L><P><F><K><P><I><F><L><G><Q><R><E><A><E><V><P><R><A><T><T><S><Q><K><C><I><R><T><N><D><I><E><N><V><G><Q><T><A><R><H><H><T><Y><F><E><M><L><G><N><F><S><F><G><D><Y><F><K><E><Q><A><I><A><W...
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP>
B0CFX4
A5WGG4
FOLD_PSYWF
Methenyltetrahydrofolate cyclohydrolase
Psychrobacter
<M><N><D><A><T><A><T><R><L><D><G><K><A><L><A><K><Q><I><E><T><E><L><S><Q><R><V><A><A><V><I><K><K><T><G><R><T><P><I><L><A><T><I><L><V><G><D><D><P><A><S><A><T><Y><V><R><M><K><G><N><A><C><K><R><V><G><M><E><S><I><R><V><E><M><P><A><S><T><T><T><E><Q><L><L><A><K><I><D><E><L><N><N><N><P><D><V><H><G><I><L><L><Q><H><P><V><P><E><Q...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
A5WGG4
O04420
URIC_ARATH
Urate oxidase
Arabidopsis
<M><A><Q><E><A><D><G><I><R><L><D><Q><R><H><G><K><A><R><V><R><V><G><R><V><W><R><H><A><H><D><G><S><H><H><F><V><E><W><N><V><S><I><S><L><L><S><H><C><L><S><S><Y><R><L><D><D><N><S><D><I><V><A><T><D><T><I><K><N><T><V><Y><V><K><A><K><E><C><G><D><R><L><S><V><E><E><F><A><I><L><I><G><K><H><F><C><S><F><Y><P><Q><V><F><T><A><I><V><N...
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.<BOP>
O04420
Q5X709
ALR_LEGPA
Alanine racemase
Legionella
<M><S><R><P><T><R><L><V><I><E><P><S><A><L><L><H><N><L><S><Q><I><K><H><L><A><P><G><K><K><V><I><A><M><V><K><A><N><A><Y><G><C><G><V><R><E><V><A><P><V><L><D><G><R><I><E><A><F><G><V><A><C><L><E><E><A><L><A><I><R><A><L><G><V><E><T><P><C><I><L><F><Q><G><V><F><S><S><D><E><L><S><V><A><V><E><N><D><F><A><C><V><L><H><H><A><Q><Q><L...
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.<BOP>
Q5X709
P07323
ENOG_RAT
Neuron-specific enolase
Rattus
<M><S><I><Q><K><I><W><A><R><E><I><L><D><S><R><G><N><P><T><V><E><V><D><L><H><T><A><K><G><L><F><R><A><A><V><P><S><G><A><S><T><G><I><Y><E><A><L><E><L><R><D><G><D><K><Q><R><Y><L><G><K><G><V><L><K><A><V><D><H><I><N><S><T><I><A><P><A><L><I><S><S><G><L><S><V><V><E><Q><E><K><L><D><N><L><M><L><E><L><D><G><T><E><N><K><S><K><F><G...
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.<BOP>
P07323
B2VDH0
MGSA_ERWT9
Methylglyoxal synthase
Erwinia
<M><D><Q><T><T><R><T><V><Q><A><Q><K><H><I><A><L><V><A><H><D><H><C><K><T><S><L><M><Q><W><V><A><I><H><K><E><K><L><Q><H><H><I><L><Y><A><T><G><T><T><G><H><L><V><Q><R><A><T><G><L><P><V><T><A><M><M><S><G><P><M><G><G><D><Q><Q><V><G><A><L><I><S><E><G><R><I><D><L><L><I><F><F><W><D><P><L><N><A><V><P><H><D><P><D><V><K><A><L><L><R...
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.<BOP>
B2VDH0
A9KIA6
SYDND_LACP7
Non-discriminating aspartyl-tRNA synthetase
Lachnospiraceae
<M><A><E><S><M><K><G><L><H><R><T><H><R><C><T><E><L><S><N><S><N><V><G><E><I><V><T><V><M><G><W><V><Q><K><S><R><N><K><G><G><I><I><F><V><D><L><R><D><R><S><G><L><L><Q><I><I><F><E><E><G><D><I><G><T><E><M><F><E><K><A><S><K><L><R><S><E><F><V><V><A><V><V><G><K><V><E><T><R><S><G><A><V><N><E><N><L><L><T><G><T><I><E><V><R><A><T><E...
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP>
A9KIA6
B8I761
FOLD_RUMCH
Methenyltetrahydrofolate cyclohydrolase
Ruminiclostridium
<M><S><A><K><V><L><N><G><T><E><L><A><A><K><V><K><A><G><L><K><A><K><I><D><E><L><K><S><K><G><I><N><P><G><L><A><V><I><I><V><G><D><D><P><A><S><R><V><Y><V><N><H><K><K><N><D><C><T><E><I><G><I><K><S><F><E><Y><A><L><P><E><S><T><S><E><E><E><L><L><D><L><I><E><T><L><N><N><D><A><S><V><N><G><I><L><V><Q><L><P><I><P><K><H><I><N><E><E...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
B8I761
A6T0Z0
RIMP_JANMA
Ribosome maturation factor RimP
Janthinobacterium
<M><Q><L><S><A><L><I><E><K><T><V><V><G><M><G><Y><E><L><V><N><F><E><Q><A><A><R><G><L><V><R><V><F><I><D><F><T><P><E><D><A><D><K><G><A><I><T><V><E><D><C><E><K><V><T><H><Q><L><L><H><V><L><T><V><E><N><A><N><Y><E><R><L><E><V><S><S><P><G><L><D><R><P><L><K><K><L><S><D><Y><V><R><F><A><G><A><E><A><L><V><K><L><R><M><P><M><P><N><A...
Required for maturation of 30S ribosomal subunits.<BOP>
A6T0Z0
A9AAK2
PYRI_METM6
Aspartate carbamoyltransferase regulatory chain
Methanococcus
<M><K><M><E><L><K><V><K><P><I><E><N><G><T><V><I><D><H><I><S><G><S><K><A><L><K><V><Y><K><I><L><N><I><E><E><K><L><P><I><T><L><A><L><N><V><P><S><K><K><G><V><M><K><D><I><L><K><I><E><G><L><E><L><T><R><D><D><V><N><K><I><A><L><I><S><P><D><A><T><I><N><I><I><K><E><G><I><V><I><K><K><F><K><V><N><L><P><K><R><I><D><G><I><I><K><C><T...
Involved in allosteric regulation of aspartate carbamoyltransferase.<BOP>
A9AAK2
Q5VTY9
HHAT_HUMAN
Skinny hedgehog protein 1
Homo
<M><L><P><R><W><E><L><A><L><Y><L><L><A><S><L><G><F><H><F><Y><S><F><Y><E><V><Y><K><V><S><R><E><H><E><E><E><L><D><Q><E><F><E><L><E><T><D><T><L><F><G><G><L><K><K><D><A><T><D><F><E><W><S><F><W><M><E><W><G><K><Q><W><L><V><W><L><L><L><G><H><M><V><V><S><Q><M><A><T><L><L><A><R><K><H><R><P><W><I><L><M><L><Y><G><M><W><A><C><W><C...
Palmitoyl acyltransferase that catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling . It also catalyzes N-terminal palmitoylation of DHH . Promotes the transfer of palmitoyl-CoA from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane, where SHH palmitoylation occurs . I...
Q5VTY9
B7MM76
IDI_ECO45
Isopentenyl pyrophosphate isomerase
Escherichia
<M><Q><T><E><H><V><I><L><L><N><A><Q><G><V><P><T><G><T><L><E><K><Y><A><A><H><T><A><D><T><L><L><H><L><A><F><S><S><W><L><F><N><A><K><G><Q><L><L><V><T><R><R><A><L><S><K><K><A><W><P><G><V><W><T><N><S><V><C><G><H><P><Q><L><G><E><S><N><E><E><A><V><I><R><R><C><R><Y><E><L><G><V><E><I><T><P><P><E><S><I><Y><P><D><F><R><Y><R><A><T...
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).<BOP>
B7MM76
Q3ZZT1
MTNA_DEHMC
S-methyl-5-thioribose-1-phosphate isomerase
Dehalococcoides
<M><K><A><I><E><W><R><N><N><R><L><I><I><L><D><Q><T><L><L><P><L><E><E><K><Y><L><E><L><N><D><Y><H><A><V><A><E><A><I><K><T><L><R><I><R><G><A><P><S><I><G><V><A><A><A><Y><G><I><A><L><G><A><L><S><I><E><T><R><Y><C><S><E><F><L><P><L><Y><Q><Q><I><S><A><E><I><A><S><T><R><P><T><A><K><N><L><F><M><A><V><E><R><M><D><H><V><V><A><S><G...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
Q3ZZT1
P54884
REGX3_MYCLE
Sensory transduction protein RegX3
Mycobacterium
<M><V><T><D><G><P><A><A><L><A><E><F><D><R><S><G><A><D><I><V><L><L><D><L><M><L><P><G><M><S><G><T><D><V><Y><K><Q><L><R><V><R><S><S><V><P><V><I><M><V><T><A><R><D><S><E><I><D><K><V><V><G><L><E><L><G><A><D><D><Y><V><T><K><P><Y><S><A><R><E><L><I><A><R><I><R><A><V><L><R><R><G><G><D><D><D><S><E><I><S><D><G><V><L><E><S><G><P><L...
Probably forms part of a two-component regulatory system RegX3/SenX3.<BOP>
P54884
Q9M9E0
LRKS1_ARATH
L-type lectin-domain containing receptor kinase S.1
Arabidopsis
<M><S><W><Q><W><R><R><R><Q><W><P><S><P><L><L><L><I><L><I><V><L><H><L><V><S><S><S><S><A><I><D><F><L><Y><N><S><F><S><S><V><T><N><R><T><D><V><I><L><I><E><D><S><R><V><E><S><T><V><I><S><L><I><N><D><S><D><P><L><S><F><G><R><V><F><Y><P><Q><K><L><T><I><I><P><D><P><T><R><N><P><T><R><L><S><S><F><S><T><S><F><V><F><S><I><L><P><D><I...
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.<BOP>
Q9M9E0
Q7NQN3
UBID_CHRVO
Polyprenyl p-hydroxybenzoate decarboxylase
Chromobacterium
<M><K><Y><A><D><L><R><E><F><I><A><Q><L><E><Q><K><Q><L><L><K><R><I><K><T><P><V><S><P><H><L><E><M><T><E><I><G><D><R><V><L><K><A><G><G><P><A><L><L><F><E><Q><P><V><D><N><G><R><R><Y><D><F><P><V><L><A><N><L><F><G><T><P><E><R><V><A><M><G><M><G><A><D><D><V><M><Q><L><R><E><I><G><R><T><L><A><Y><L><K><E><P><E><P><P><K><G><L><K><D...
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP>
Q7NQN3
A8GW07
CH60_RICB8
Chaperonin-60
belli group
<M><A><T><K><L><I><K><H><G><S><K><A><R><E><Q><M><L><E><G><I><D><I><L><A><D><A><V><K><V><T><L><G><P><K><G><R><N><V><L><I><E><Q><S><F><G><A><P><K><I><T><K><D><G><V><T><V><A><K><S><I><E><L><K><D><K><I><R><N><A><G><A><Q><L><L><K><S><A><A><T><K><A><A><E><V><A><G><D><G><T><T><T><A><T><V><L><A><R><A><L><A><R><E><G><N><K><L><V...
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP>
A8GW07
B3DS08
LGT_BIFLD
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Bifidobacterium
<M><N><L><A><Y><I><P><S><P><T><F><S><K><F><E><I><G><P><F><T><I><H><M><Y><A><I><C><I><L><I><G><I><C><V><A><V><W><I><L><T><T><R><W><K><R><Y><G><G><T><F><D><Q><I><L><D><T><T><L><V><T><V><P><C><A><L><V><G><A><R><L><Y><H><C><I><T><T><P><A><D><Y><F><P><P><T><G><N><L><V><N><I><L><K><V><W><E><G><G><M><A><I><F><G><G><I><S><V><G...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
B3DS08
Q83P87
MDTP_SHIFL
Multidrug resistance outer membrane protein MdtP
Shigella
<M><I><N><R><Q><L><S><R><L><L><L><C><S><I><L><G><S><T><T><L><I><S><G><C><A><L><V><R><K><D><S><A><P><H><Q><Q><L><K><P><E><Q><I><K><L><A><D><D><I><H><L><A><S><S><G><W><P><Q><A><Q><W><W><K><Q><L><N><D><P><Q><L><D><A><L><I><Q><R><T><L><S><G><S><H><T><L><A><E><A><K><L><R><E><E><K><A><Q><S><Q><A><D><L><L><D><A><G><S><Q><L><Q...
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.<BOP>
Q83P87
P9WLN1
Y2005_MYCTU
Universal stress protein Rv2005c
Mycobacterium tuberculosis complex
<M><S><K><P><R><K><Q><H><G><V><V><V><G><V><D><G><S><L><E><S><D><A><A><A><C><W><G><A><T><D><A><A><M><R><N><I><P><L><T><V><V><H><V><V><N><A><D><V><A><T><W><P><P><M><P><Y><P><E><T><W><G><V><W><Q><E><D><E><G><R><Q><I><V><A><N><A><V><K><L><A><K><E><A><V><G><A><D><R><K><L><S><V><K><S><E><L><V><F><S><T><P><V><P><T><M><V><E><I...
Probably involved in aminoglycosides resistance and virulence. Overexpression increases resistance to the aminoglycosides amikacin (AK) and kanamycin (KM).<BOP>
P9WLN1
Q9PDT6
ISPD_XYLFA
MEP cytidylyltransferase
Xylella
<M><S><V><G><V><W><A><V><I><P><A><A><G><R><G><V><R><F><G><S><P><V><P><K><Q><Y><L><P><V><V><G><R><P><L><I><V><Y><T><L><E><A><L><A><A><H><P><A><V><C><G><L><M><V><V><V><A><E><G><D><L><A><W><S><S><W><T><E><V><A><G><K><P><L><L><T><C><S><G><G><V><T><R><A><A><S><V><L><S><G><L><L><A><L><P><Q><V><V><H><A><D><D><F><V><L><V><H><D...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q9PDT6
Q6LUJ2
IF2_PHOPR
Translation initiation factor IF-2
Photobacterium
<M><S><E><V><T><V><K><A><L><A><E><E><V><G><T><P><I><D><R><L><L><Q><Q><F><S><D><A><G><I><S><K><K><A><E><D><N><V><S><Q><T><E><K><Q><S><L><L><S><H><L><Q><K><E><H><G><G><E><S><T><D><G><T><P><T><R><L><T><L><Q><R><K><T><H><S><T><L><S><V><A><G><T><G><G><K><S><K><S><V><Q><V><E><V><R><K><K><R><T><F><V><K><R><S><A><L><E><E><E><Q...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
Q6LUJ2
A8FMK7
GMHA_CAMJ8
Sedoheptulose 7-phosphate isomerase
Campylobacter
<M><I><N><L><V><E><K><E><W><Q><E><H><Q><K><I><A><Q><E><S><E><I><L><K><G><Q><I><A><K><A><G><E><L><L><C><E><C><L><K><K><G><G><K><I><L><I><C><G><N><G><G><S><A><A><D><A><Q><H><F><A><A><E><L><S><G><R><Y><K><K><E><R><K><A><L><A><G><I><A><L><T><T><D><T><S><A><L><S><A><I><G><N><D><Y><G><F><E><F><V><F><S><R><Q><V><E><A><L><G><N...
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.<BOP>
A8FMK7
B0JR86
UVRB_MICAN
Excinuclease ABC subunit B
Microcystis
<M><T><A><F><Q><L><Q><A><P><F><Q><P><T><G><D><Q><P><A><A><I><D><Q><L><V><D><S><L><Q><N><Q><H><R><F><Q><T><L><L><G><A><T><G><T><G><K><T><F><T><I><A><A><V><I><E><K><I><G><R><P><T><L><V><L><A><H><N><K><T><L><A><A><Q><L><C><N><E><L><R><Q><F><F><P><N><N><A><V><E><Y><F><I><S><Y><Y><D><Y><Y><Q><P><E><A><Y><I><P><V><S><D><T><Y...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
B0JR86
B8FZ81
TAL_DESHD
Probable transaldolase
Desulfitobacterium
<M><E><F><L><L><D><S><A><N><P><E><E><I><R><Q><A><W><A><M><G><V><I><G><G><I><T><T><N><P><S><L><V><A><K><E><G><R><D><F><H><Q><L><L><Q><E><L><V><Q><I><V><N><G><P><I><S><A><E><V><I><A><L><D><T><E><G><M><L><G><E><A><R><E><L><A><A><M><H><P><N><I><V><V><K><I><P><M><T><E><E><G><L><K><A><V><K><V><L><K><A><E><G><I><K><T><N><V><T...
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP>
B8FZ81
C5BMS3
FTSB_TERTT
Cell division protein FtsB
Teredinibacter
<M><K><W><L><V><A><V><L><V><V><F><V><A><M><F><Q><Y><R><L><W><V><G><E><G><S><I><A><D><V><V><R><L><E><R><E><I><A><R><Q><E><A><D><N><E><R><L><R><E><R><N><K><Q><L><A><A><E><V><D><A><L><K><T><G><D><D><A><I><E><E><R><A><R><S><D><M><G><M><I><K><E><G><E><T><F><F><M><I><I><D><D><Q>
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.<BOP>
C5BMS3
A1VI55
MINE_POLNA
Cell division topological specificity factor
Polaromonas
<M><A><S><F><F><S><F><L><L><G><E><K><K><K><T><A><N><V><A><K><E><R><L><Q><I><I><L><A><H><E><R><S><G><R><N><S><H><E><P><D><Y><L><P><A><L><Q><R><D><L><I><A><V><I><A><K><Y><I><N><I><N><P><N><D><I><K><L><N><L><E><R><Q><E><N><L><D><V><L><E><V><K><I><E><L><P><D><K>
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.<BOP>
A1VI55
A4SRC1
ENO_AERS4
2-phosphoglycerate dehydratase
Aeromonas
<M><S><K><I><V><K><V><I><G><R><E><I><I><D><S><R><G><N><P><T><V><E><A><E><V><H><L><E><G><G><F><V><G><M><A><A><A><P><S><G><A><S><T><G><S><R><E><A><L><E><L><R><D><G><D><K><S><R><F><L><G><K><G><V><L><K><A><L><E><A><V><N><G><P><I><A><Q><A><L><L><G><K><D><A><K><D><Q><A><A><I><D><Q><I><M><I><D><L><D><G><T><E><N><K><S><K><F><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
A4SRC1
P10727
SP2AA_BACSU
Stage II sporulation protein AA
Bacillus
<M><S><L><G><I><D><M><N><V><K><E><S><V><L><C><I><R><L><T><G><E><L><D><H><H><T><A><E><T><L><K><Q><K><V><T><Q><S><L><E><K><D><D><I><R><H><I><V><L><N><L><E><D><L><S><F><M><D><S><S><G><L><G><V><I><L><G><R><Y><K><Q><I><K><Q><I><G><G><E><M><V><V><C><A><I><S><P><A><V><K><R><L><F><D><M><S><G><L><F><K><I><I><R><F><E><Q><S><E><Q...
In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.<BOP>
P10727
Q15884
EREP1_HUMAN
Endosomal transmembrane binding with epsin
Homo
<M><I><L><L><V><N><L><F><V><L><L><S><V><V><C><V><L><L><N><L><A><G><F><I><L><G><C><Q><G><A><Q><F><V><S><S><V><P><R><C><D><L><V><D><L><G><E><G><K><I><C><F><C><C><E><E><F><Q><P><A><K><C><T><D><K><E><N><A><L><K><L><F><P><V><Q><P><C><S><A><V><H><L><L><L><K><K><V><L><F><A><L><C><A><L><N><A><L><T><T><T><V><C><L><V><A><A><A><L...
Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway.<BOP>
Q15884
P08928
LAM0_DROME
Lamin Dm0
Sophophora
<M><S><S><K><S><R><R><A><G><T><A><T><P><Q><P><G><N><T><S><T><P><R><P><P><S><A><G><P><Q><P><P><P><P><S><T><H><S><Q><T><A><S><S><P><L><S><P><T><R><H><S><R><V><A><E><K><V><E><L><Q><N><L><N><D><R><L><A><T><Y><I><D><R><V><R><N><L><E><T><E><N><S><R><L><T><I><E><V><Q><T><T><R><D><T><V><T><R><E><T><T><N><I><K><N><I><F><E><A><E...
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin . May have a role in the localization of the LEM domain proteins Ote, bocks and MAN1 to the nuclear ...
P08928
A2CEH0
POC1B_DANRE
WD repeat domain 51B
Danio
<M><A><S><V><M><E><D><P><T><L><E><R><H><F><K><G><H><K><D><V><I><S><C><A><D><F><N><P><N><N><K><Q><L><A><T><G><S><C><D><K><S><L><M><I><W><N><L><A><P><K><A><R><A><F><R><F><V><G><H><T><D><V><I><T><G><V><N><F><A><P><S><G><S><L><V><A><S><S><S><R><D><Q><T><V><R><L><W><T><P><S><I><K><G><E><S><T><V><F><K><A><H><T><A><S><V><R><S...
Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control.<BOP>
A2CEH0
Q1AGS8
HBA2_BORSA
Hemoglobin alpha-2 chain
Boreogadus
<M><S><L><S><A><K><D><K><A><T><V><K><L><F><W><G><K><M><S><G><K><S><E><L><I><G><A><D><A><L><S><R><M><L><A><V><Y><P><Q><T><K><I><Y><F><S><H><W><K><S><C><S><P><G><S><P><E><V><K><K><H><G><K><T><I><M><M><G><I><G><E><A><V><T><K><M><D><D><L><E><R><G><L><L><T><L><S><E><L><H><A><F><K><L><R><V><D><P><T><N><F><K><L><L><S><L><N><I...
Involved in oxygen transport from gills to the various peripheral tissues.<BOP>
Q1AGS8
Q2FTH0
GPMA_METHJ
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Methanospirillum
<M><Y><T><L><V><L><I><R><H><G><E><S><L><W><N><R><E><N><R><F><T><G><W><R><D><I><D><L><S><P><Q><G><I><D><E><A><R><A><A><G><K><A><L><R><E><Q><G><F><E><F><D><L><A><Y><T><S><V><L><K><R><A><I><R><T><L><W><L><I><Q><E><E><M><D><L><M><W><I><P><V><I><R><T><W><R><L><N><E><R><H><Y><G><A><L><T><G><L><N><K><I><E><T><V><E><K><Y><G><E...
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP>
Q2FTH0
B3M4D9
EIF3E_DROAN
Eukaryotic translation initiation factor 3 subunit 6
Sophophora
<M><A><Q><F><D><L><T><R><I><N><C><Q><Y><L><D><R><H><L><T><F><P><L><L><E><F><L><C><G><K><E><I><Y><N><Q><Q><E><L><L><E><Y><I><L><E><T><V><N><K><T><N><M><I><D><Y><T><M><D><T><R><K><R><L><N><L><S><Q><E><M><P><E><E><L><V><Q><R><K><A><E><V><L><A><T><L><K><Q><L><Q><N><E><V><A><P><I><M><K><A><T><D><I><L><K><N><G><E><S><M><K><D...
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates t...
B3M4D9
C5BKJ4
ATPE_TERTT
F-ATPase epsilon subunit
Teredinibacter
<M><A><L><T><I><H><C><N><I><V><S><A><E><Q><E><I><F><S><G><L><V><E><L><L><V><A><A><A><T><E><G><D><V><G><I><G><Y><G><H><A><P><F><L><S><A><L><K><P><G><P><V><R><V><K><K><Q><S><G><D><E><E><I><F><Y><V><S><G><G><Y><L><E><V><Q><P><E><S><I><N><V><L><A><D><T><A><L><R><A><D><D><M><D><E><A><S><A><E><A><A><K><K><E><A><E><E><A><L><A...
Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP>
C5BKJ4
A3Q9U9
HSLV_SHELP
ATP-dependent protease subunit HslV
Shewanella
<M><T><T><I><V><S><V><R><R><N><N><Q><V><V><I><A><G><D><G><Q><V><S><L><G><N><T><V><M><K><G><N><A><R><K><V><R><R><L><Y><H><N><K><V><L><A><G><F><A><G><G><T><A><D><A><F><T><L><F><E><R><F><E><S><K><L><E><M><H><Q><G><H><L><M><R><A><A><V><E><M><A><K><D><W><R><S><D><R><V><L><R><K><L><E><A><L><L><A><V><A><D><T><E><C><S><L><I><I...
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.<BOP>
A3Q9U9
B8CI02
TATB_SHEPW
Sec-independent protein translocase protein TatB
Shewanella
<M><F><D><G><I><G><F><M><E><L><L><L><I><G><V><L><G><L><V><V><L><G><P><E><R><L><P><V><A><V><R><S><I><S><G><W><I><R><A><M><K><K><M><A><N><S><V><K><D><E><L><E><Q><E><L><K><I><E><Q><L><H><T><D><L><K><K><A><E><N><Q><G><L><K><N><L><A><P><E><L><Q><D><S><I><D><Q><L><K><Q><A><A><E><S><V><N><R><P><Y><Q><V><E><D><A><P><S><A><K><E...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that...
B8CI02
Q60185
VATF_METMA
V-ATPase subunit F
Methanosarcina
<M><E><L><A><V><I><G><K><S><E><F><V><T><G><F><R><L><A><G><I><S><K><V><Y><E><T><P><D><I><P><A><T><E><S><A><V><R><S><V><L><E><D><K><S><V><G><I><L><V><M><H><N><D><D><I><G><N><L><P><E><V><L><R><K><N><L><N><E><S><V><Q><P><T><V><V><A><L><G><G><S><G><S><G><S><T><S><L><R><E><K><I><K><Q><A><V><G><V><D><L><W><K>
Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP>
Q60185
B7JKG2
KHSE_BACC0
Homoserine kinase
Bacillus cereus group
<M><I><P><L><S><I><R><V><P><A><S><T><A><N><V><G><P><G><F><D><S><V><G><I><A><L><S><L><Y><L><H><V><V><V><K><E><K><S><D><K><W><Q><V><I><H><S><F><E><D><S><I><P><T><D><D><K><N><L><I><V><S><T><A><C><K><V><C><P><S><L><S><P><H><I><I><E><V><T><S><N><I><P><L><T><R><G><L><G><S><S><A><S><A><I><V><A><G><I><E><L><A><N><Q><L><G><K><L...
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.<BOP>
B7JKG2
A7HWS7
RL18_PARL1
50S ribosomal protein L18
Parvibaculum
<M><S><N><M><K><T><L><S><Q><R><R><A><M><R><N><R><A><K><L><A><K><A><S><V><V><R><P><R><L><S><V><F><R><S><S><K><H><I><Y><A><Q><V><I><D><D><T><R><G><V><T><V><A><A><A><S><S><L><D><E><K><F><G><K><K><A><G><T><D><V><A><A><A><G><E><V><G><K><L><L><A><Q><R><A><K><D><A><G><I><T><D><V><V><F><D><R><G><G><Y><I><Y><H><G><R><V><K><A><L...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
A7HWS7
A4XUY1
BPT_PSEMY
Aspartate/glutamate leucyltransferase
Pseudomonas
<M><T><E><L><A><R><L><K><F><Y><A><T><Q><P><H><P><C><S><Y><L><P><A><E><Q><A><T><T><L><F><L><D><P><S><Q><P><M><D><V><L><V><Y><A><E><L><S><E><M><G><F><R><R><S><G><D><H><L><Y><R><P><H><C><Q><Q><C><T><A><C><I><P><A><R><I><P><A><A><L><F><T><P><N><R><Q><Q><R><R><I><L><K><R><N><E><D><V><S><V><H><P><V><R><P><A><F><T><E><E><Y><Y...
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.<BOP>
A4XUY1
Q2W3J7
NUON_MAGSA
NDH-1 subunit N
Magnetospirillum
<M><I><K><T><L><D><L><V><P><V><L><P><E><I><F><M><A><V><A><G><L><A><L><L><M><L><G><V><F><R><K><E><D><S><T><K><S><V><S><V><L><V><I><L><A><L><G><A><A><M><V><L><V><S><S><L><G><G><E><R><L><T><A><F><N><G><L><F><V><A><D><R><F><A><G><F><A><K><G><L><V><L><V><A><S><A><I><A><T><A><M><S><L><P><Y><L><E><R><E><K><I><G><R><F><E><Y><P...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q2W3J7
Q93WX6
CNIF1_ARATH
Selenocysteine lyase
Arabidopsis
<M><E><G><V><A><M><K><L><P><S><F><P><N><A><I><S><I><G><H><R><S><F><S><R><V><R><C><S><S><S><L><S><V><C><S><A><A><A><A><S><S><A><T><I><S><T><D><S><E><S><V><S><L><G><H><R><V><R><K><D><F><R><I><L><H><Q><E><V><N><G><S><K><L><V><Y><L><D><S><A><A><T><S><Q><K><P><A><A><V><L><D><A><L><Q><N><Y><Y><E><F><Y><N><S><N><V><H><R><G><I...
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine . Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters . Required for the maturation of all plastidic Fe-S proteins and, thus, essential for plant growth .<BOP>
Q93WX6
Q06756
ISPF_BACSU
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Bacillus
<M><F><R><I><G><Q><G><F><D><V><H><Q><L><V><E><G><R><P><L><I><I><G><G><I><E><I><P><Y><E><K><G><L><L><G><H><S><D><A><D><V><L><L><H><T><V><A><D><A><C><L><G><A><V><G><E><G><D><I><G><K><H><F><P><D><T><D><P><E><F><K><D><A><D><S><F><K><L><L><Q><H><V><W><G><I><V><K><Q><K><G><Y><V><L><G><N><I><D><C><T><I><I><A><Q><K><P><K><M><L...
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond...
Q06756
A4XAM8
COBT_SALTO
N(1)-alpha-phosphoribosyltransferase
Salinispora
<M><M><L><E><R><T><T><A><A><I><G><P><L><D><E><Q><A><M><A><T><A><A><D><L><Q><S><R><L><T><K><P><A><G><S><L><G><V><L><E><E><L><S><V><R><L><A><G><L><A><G><V><C><P><P><P><L><P><E><P><A><A><V><A><V><F><A><G><D><H><G><V><H><A><Q><G><V><T><P><W><P><Q><E><V><T><G><Q><M><I><G><N><F><L><A><G><G><A><V><V><N><A><F><A><R><Q><T><G><A...
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP>
A4XAM8
Q8NN57
NADD_CORGL
Nicotinate mononucleotide adenylyltransferase
Corynebacterium
<M><T><T><T><V><K><R><R><A><R><I><G><I><M><G><G><T><F><D><P><I><H><N><G><H><L><V><A><G><S><E><V><A><D><R><F><D><L><D><L><V><V><Y><V><P><T><G><Q><P><W><Q><K><A><N><K><K><V><S><P><A><E><D><R><Y><L><M><T><V><I><A><T><A><S><N><P><R><F><M><V><S><R><V><D><I><D><R><G><G><D><T><Y><T><I><D><T><L><Q><D><L><S><K><Q><Y><P><D><A><Q...
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP>
Q8NN57
Q9HCS2
CP4FC_HUMAN
CYPIVF12
Homo
<M><S><L><L><S><L><P><W><L><G><L><R><P><V><A><T><S><P><W><L><L><L><L><L><V><V><G><S><W><L><L><A><R><I><L><A><W><T><Y><A><F><Y><N><N><C><R><R><L><Q><C><F><P><Q><P><P><K><R><N><W><F><W><G><H><L><G><L><I><T><P><T><E><E><G><L><K><N><S><T><Q><M><S><A><T><Y><S><Q><G><F><T><V><W><L><G><P><I><I><P><F><I><V><L><C><H><P><D><T><I...
A cytochrome P450 monooxygenase involved in the metabolism of endogenous polyunsaturated fatty acids (PUFAs). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-f...
Q9HCS2
Q2LSG2
RNPA_SYNAS
Protein C5
Syntrophus
<M><K><K><L><T><L><K><K><S><E><R><I><R><K><R><R><S><Y><L><Q><I><Y><Q><H><G><K><R><S><F><T><K><H><F><T><I><V><V><S><E><N><D><L><D><F><P><R><L><G><M><T><V><T><K><K><I><G><N><A><V><K><R><N><R><I><K><R><L><I><R><E><F><F><R><L><N><K><D><R><F><K><A><S><Q><D><I><V><I><I><A><K><G><N><T><S><S><M><K><Y><A><D><V><C><R><E><L><G><V...
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz...
Q2LSG2
Q82WM1
ISPH_NITEU
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Nitrosomonas
<M><I><R><V><L><L><A><N><P><R><G><F><C><A><G><V><D><R><A><I><E><I><V><E><R><A><L><A><M><Y><G><A><P><I><Y><V><R><H><E><V><V><H><N><R><F><V><V><E><D><L><E><K><K><G><A><V><F><V><E><N><L><E><E><V><P><E><G><S><M><L><I><F><S><A><H><G><V><S><H><E><V><R><R><E><A><A><A><R><K><L><Q><I><F><D><A><T><C><P><L><V><T><K><V><H><V><E><V...
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.<BOP>
Q82WM1
C1CBB5
MRAY_STRP7
UDP-MurNAc-pentapeptide phosphotransferase
Streptococcus
<M><F><I><S><I><S><A><G><I><V><T><F><L><L><T><L><V><E><I><P><A><F><I><Q><F><Y><R><K><A><Q><I><T><G><Q><Q><M><H><E><D><V><K><Q><H><Q><A><K><A><G><T><P><T><M><G><G><L><V><F><L><I><T><S><V><L><V><A><F><F><F><A><L><F><S><S><Q><F><S><N><N><V><G><M><I><L><F><I><L><V><L><Y><G><L><V><G><F><L><D><D><F><L><K><V><F><R><K><I><N><E...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
C1CBB5
Q5RF92
RBBP4_PONAB
Retinoblastoma-binding protein 4
Pongo
<M><A><D><K><E><A><A><F><D><D><A><V><E><E><R><V><I><N><E><E><H><K><I><W><K><K><N><T><P><F><L><Y><D><L><V><M><T><H><A><L><E><W><P><S><L><T><A><Q><W><L><P><D><V><T><R><P><E><G><K><D><F><S><I><H><R><L><V><L><G><T><H><T><S><D><E><Q><N><H><L><V><I><A><S><V><Q><L><P><N><D><D><A><Q><F><D><A><S><H><Y><D><S><E><K><G><E><F><G><G...
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (...
Q5RF92
Q1IIG8
ATPB_KORVE
F-ATPase subunit beta
Candidatus Koribacter
<M><A><E><N><F><G><K><V><I><Q><I><S><G><P><A><V><D><V><Q><F><S><E><T><T><L><P><E><I><Y><T><A><L><R><V><V><S><E><G><F><D><V><P><T><P><I><N><V><V><L><E><I><Q><Q><H><L><G><E><G><R><V><R><C><V><A><M><E><P><T><E><G><M><V><R><G><M><K><A><I><D><M><G><G><P><I><S><V><P><V><G><R><G><T><L><G><R><V><M><N><V><I><G><E><P><V><D><Q><L...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
Q1IIG8
P80977
CX6C1_THUOB
Cytochrome c oxidase polypeptide VIc-1
Thunnus
<M><S><L><A><K><P><A><M><R><G><L><L><G><K><R><L><R><F><H><L><P><I><A><F><T><L><S><L><V><A><A><L><G><F><K><Y><G><V><T><E><P><R><K><Q><A><Y><A><D><F><Y><K><Q><Y><D><A><V><K><D><F><N><A><M><R><E><A><G><I><F><E><S><V><R><P><S><G><E>
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII...
P80977
Q9I154
PK21B_PSEAE
Polyphosphate kinase PPK2 2
Pseudomonas
<M><D><S><Y><G><D><T><S><G><R><I><G><R><D><W><L><D><R><H><D><E><E><L><E><Q><E><L><L><D><D><E><L><N><L><D><E><L><F><G><P><E><Q><E><D><A><P><G><E><L><S><R><R><R><Y><F><R><E><L><F><R><L><Q><R><E><L><V><K><L><Q><N><W><V><V><H><T><G><H><K><V><V><I><L><F><E><G><R><D><A><A><G><K><G><G><V><I><K><R><I><T><Q><R><L><N><P><R><V><C...
Uses inorganic polyphosphate (polyP) as a donor to convert ADP to ATP.<BOP>
Q9I154
Q8PPW9
MDCG_XANAC
Malonate decarboxylase holo-[acyl-carrier-protein] synthase
Xanthomonas
<M><A><G><R><H><A><L><V><W><L><R><E><D><A><Q><W><Q><A><V><T><S><G><A><Q><P><R><L><Q><Q><W><F><A><A><G><L><P><A><V><V><A><R><G><D><G><S><Q><A><P><G><T><L><R><L><G><V><P><L><P><P><S><E><G><K><Q><R><L><A><L><Q><A><H><V><A><G><I><A><R><C><T><A><P><L><T><L><D><A><V><M><P><H><A><P><L><A><V><Q><P><A><L><Q><A><L><L><A><Q><A><H...
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].<BOP>
Q8PPW9