accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
B2Y1X2
CYF_WELMI
Cytochrome f
Welwitschia
<M><E><K><R><N><T><Y><D><W><V><T><R><W><V><I><A><S><F><S><I><L><T><I><S><Y><M><I><T><W><T><S><I><S><N><A><Y><P><I><F><A><Q><K><S><Y><E><S><P><R><E><A><T><G><R><I><V><C><A><N><C><H><L><A><K><K><S><V><E><I><E><V><P><Q><S><V><L><P><N><S><V><F><E><A><I><V><K><I><P><Y><D><T><Q><I><K><Q><V><L><A><N><G><K><K><G><G><L><N><V><G...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
B2Y1X2
Q9EV79
6PGL_PSEPU
6-phosphogluconolactonase
Pseudomonas
<M><G><G><R><G><M><G><I><S><E><L><K><L><P><A><A><V><K><V><H><E><L><A><D><A><K><T><L><A><A><T><L><A><H><D><V><A><E><R><L><R><A><A><I><A><A><K><G><Q><A><C><V><V><L><S><G><G><R><S><P><V><P><F><L><E><K><L><A><S><E><P><L><D><W><A><K><V><T><V><S><L><A><D><E><R><W><V><P><V><E><H><A><D><S><N><A><G><L><L><A><R><H><L><L><T><G><A...
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.<BOP>
Q9EV79
Q8DEK8
MURD_VIBVU
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Vibrio
<M><D><R><W><Q><D><I><K><Q><V><V><V><V><G><L><G><I><T><G><L><S><V><V><R><H><L><R><K><T><Q><P><Q><L><Q><V><K><V><I><D><T><R><P><T><P><P><G><V><E><Q><L><P><P><D><I><A><L><H><V><G><S><W><N><D><A><W><L><A><E><A><D><L><V><V><T><N><P><G><I><A><L><A><T><P><Q><I><Q><T><V><L><A><R><G><V><A><V><V><G><D><I><E><L><F><A><W><A><A><D...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
Q8DEK8
A0PXW1
RL6_CLONN
50S ribosomal protein L6
Clostridium
<M><S><R><V><G><R><L><P><I><E><I><P><N><G><V><N><V><T><V><T><P><E><N><V><V><T><V><K><G><P><K><G><E><L><T><K><A><M><H><E><D><M><N><I><A><V><E><E><N><N><I><V><V><T><R><P><S><E><N><V><Q><H><K><A><L><H><G><L><T><R><A><L><I><N><N><M><V><V><G><V><T><Q><G><Y><E><K><T><L><E><L><V><G><V><G><Y><R><A><Q><L><K><G><K><D><L><T><L><N...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
A0PXW1
P61411
THIE_GEOSL
Thiamine-phosphate pyrophosphorylase
Geobacter
<M><A><K><V><D><F><S><L><Y><L><I><T><D><R><H><Q><A><G><G><R><D><L><L><A><V><V><E><G><A><L><A><G><G><V><R><C><V><Q><L><R><E><K><D><L><P><A><R><T><L><L><E><L><A><R><A><M><R><R><L><T><D><R><F><G><A><R><L><L><I><N><D><R><V><D><I><A><L><A><A><G><A><D><G><V><H><L><G><E><E><G><M><P><A><A><V><A><R><E><L><L><G><S><G><R><L><I><G...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
P61411
B1L838
LEXA_THESQ
LexA repressor
unclassified Thermotoga
<M><K><D><L><T><E><R><Q><R><K><V><L><L><F><I><E><E><F><I><E><K><N><G><Y><P><P><S><V><R><E><I><A><R><R><F><R><I><T><P><R><G><A><L><L><H><L><I><A><L><E><K><K><G><Y><I><E><R><K><N><G><K><P><R><A><L><R><V><S><K><S><I><R><N><K><I><P><L><I><G><E><I><R><A><G><E><K><R><E><A><I><E><Y><L><E><D><Y><I><E><I><P><E><S><F><L><S><S><G...
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair...
B1L838
Q4ZWQ0
SURE_PSEU2
Nucleoside 5'-monophosphate phosphohydrolase
Pseudomonas syringae
<M><R><I><L><I><S><N><D><D><G><V><N><A><P><G><L><V><A><L><H><A><A><L><A><D><Y><A><D><C><V><V><I><A><P><D><Q><D><K><S><G><A><S><S><S><L><T><L><D><R><P><L><H><P><H><T><L><E><N><G><F><I><S><V><N><G><T><P><T><D><C><V><H><L><G><I><H><G><L><L><E><R><Q><P><D><M><V><V><S><G><I><N><L><G><A><N><L><G><D><D><V><L><Y><S><G><T><V><A...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
Q4ZWQ0
Q0I6K7
RL11_SYNS3
50S ribosomal protein L11
unclassified Synechococcus
<M><A><K><K><V><V><A><V><I><K><L><A><L><Q><A><G><K><A><N><P><A><P><P><V><G><P><A><L><G><Q><H><G><V><N><I><M><A><F><C><K><E><Y><N><A><R><T><Q><D><K><A><G><Y><V><I><P><V><E><I><S><V><F><E><D><R><S><F><T><F><I><T><K><T><P><P><A><S><V><L><I><T><K><A><A><G><I><Q><K><G><S><G><E><S><A><K><G><S><V><G><S><I><N><R><S><Q><L><E><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
Q0I6K7
Q3B6W8
ATPB1_CHLL3
F-ATPase subunit beta 1
Pelodictyon
<M><Q><E><G><K><I><S><Q><I><I><G><P><V><V><D><V><D><F><P><E><G><Q><L><P><S><I><L><D><A><L><T><I><T><R><P><D><G><S><R><L><V><L><E><T><Q><Q><H><L><G><E><E><R><V><R><T><V><A><M><E><S><T><D><G><L><I><R><G><L><S><V><A><N><T><G><R><P><I><Q><A><P><V><G><E><G><V><L><G><R><M><L><N><V><V><G><D><P><I><D><G><R><G><P><V><N><A><T><K...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
Q3B6W8
Q2IJA7
IHFA_ANADE
Integration host factor subunit alpha
Anaeromyxobacter
<M><T><K><A><D><I><I><E><S><V><Y><E><K><V><G><F><S><K><K><E><A><A><E><I><V><E><M><V><F><D><T><I><K><E><T><L><E><R><G><E><K><I><K><I><S><G><F><G><N><F><I><V><R><D><K><K><S><R><V><G><R><N><P><Q><T><G><E><E><I><E><I><S><A><R><R><V><L><T><F><R><P><S><Q><V><L><K><N><A><L><N><G><G><V><S><D><E><T><E><G><A><D><D><D><D><D><D><E...
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP>
Q2IJA7
P00782
SUBT_BACAM
Subtilisin Novo
Bacillus amyloliquefaciens group
<M><R><G><K><K><V><W><I><S><L><L><F><A><L><A><L><I><F><T><M><A><F><G><S><T><S><S><A><Q><A><A><G><K><S><N><G><E><K><K><Y><I><V><G><F><K><Q><T><M><S><T><M><S><A><A><K><K><K><D><V><I><S><E><K><G><G><K><V><Q><K><Q><F><K><Y><V><D><A><A><S><A><T><L><N><E><K><A><V><K><E><L><K><K><D><P><S><V><A><Y><V><E><E><D><H><V><A><H><A><Y...
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin.<BOP>
P00782
P07367
LHA2_RHOCA
LH-2
Rhodobacter
<M><N><N><A><K><I><W><T><V><V><K><P><S><T><G><I><P><L><I><L><G><A><V><A><V><A><A><L><I><V><H><A><G><L><L><T><N><T><T><W><F><A><N><Y><W><N><G><N><P><M><A><T><V><V><A><V><A><P><A><Q>
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.<BOP>
P07367
Q08478
PIT1_ONCMY
Growth hormone factor 1
Oncorhynchus
<M><S><C><Q><A><F><S><A><D><S><F><T><T><L><A><G><D><S><L><P><L><L><M><H><H><A><S><A><A><D><C><L><P><S><S><A><S><T><H><T><H><N><M><V><S><A><V><P><S><G><L><S><L><L><Q><S><S><K><R><S><H><M><H><L><S><T><S><T><L><G><N><A><L><S><N><G><P><P><G><L><H><Y><P><V><T><P><C><H><Y><S><N><Q><Q><T><T><Y><G><M><M><A><A><Q><E><M><L><S><A...
Transcription factor that activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.<BOP>
Q08478
Q1IIY8
ARGR_KORVE
Arginine repressor
Candidatus Koribacter
<M><S><K><L><S><R><H><A><A><I><R><D><A><I><T><S><H><P><V><Q><N><Q><D><E><L><R><R><L><L><F><K><R><G><H><R><V><T><Q><A><T><L><S><R><D><I><H><E><L><G><L><V><K><T><G><E><G><Y><Q><F><P><S><S><E><D><D><S><N><A><A><W><L><P><S><V><E><R><L><I><R><E><F><V><Y><D><V><K><I><A><Q><N><T><V><V><V><K><T><S><A><G><S><A><Q><P><V><A><A><A...
Regulates arginine biosynthesis genes.<BOP>
Q1IIY8
P31339
ASPA_AERSA
Microbial serine proteinase
Aeromonas
<M><R><K><T><S><L><A><L><A><I><S><A><L><L><S><A><L><P><I><A><S><V><Q><A><N><E><S><C><T><P><L><T><G><K><E><A><G><L><D><T><G><R><S><S><A><V><R><C><L><P><G><I><N><P><L><Q><D><L><L><N><S><G><Q><N><A><F><S><P><R><G><G><M><A><G><N><D><L><N><L><W><W><A><H><R><T><E><V><L><G><Q><G><I><N><V><A><V><V><D><D><G><L><A><I><A><H><P><D...
Agent of furonculosis.<BOP>
P31339
A7MQK4
CYAY_CROS8
Iron-sulfur cluster assembly protein CyaY
Cronobacter
<M><N><D><S><E><F><H><R><L><A><D><G><L><W><M><T><I><E><E><R><L><D><A><W><D><G><D><S><D><I><D><C><E><I><N><G><G><V><L><T><L><S><F><E><N><G><S><K><I><I><I><N><R><Q><E><P><L><H><Q><V><W><L><A><T><K><Q><G><G><Y><H><F><D><Y><K><N><D><E><W><I><C><D><R><S><G><E><R><F><W><D><L><L><E><T><A><A><T><Q><Q><A><G><E><A><V><S><F><R>
Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.<BOP>
A7MQK4
Q6D4E2
POTA_PECAS
Spermidine/putrescine import ATP-binding protein PotA
Pectobacterium
<M><I><C><Q><I><R><K><Q><S><Y><T><L><M><K><E><N><S><L><T><V><P><V><V><E><L><L><N><V><H><K><G><F><D><G><K><D><I><I><S><H><F><N><L><T><I><N><N><G><E><F><L><T><I><L><G><P><S><G><C><G><K><T><T><V><L><R><L><I><A><G><L><E><T><V><D><S><G><N><I><M><L><E><K><Q><D><I><T><H><Q><P><A><E><Q><R><H><V><N><T><V><F><Q><S><Y><A><L><F><P...
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.<BOP>
Q6D4E2
Q89ZG0
RNY_BACTN
Ribonuclease Y
Bacteroides
<M><I><A><I><I><A><T><A><I><A><C><F><V><V><G><G><I><L><S><Y><V><L><F><R><Y><V><L><K><S><K><Y><D><S><V><L><K><D><A><E><T><E><A><E><V><I><K><K><N><K><L><L><E><V><K><E><K><F><L><N><K><K><A><D><L><E><K><E><V><A><L><R><N><Q><K><I><Q><Q><A><E><N><K><L><K><Q><R><E><M><V><L><S><Q><R><Q><E><E><I><Q><R><K><K><L><E><A><E><A><V><K...
Endoribonuclease that initiates mRNA decay.<BOP>
Q89ZG0
Q06106
MRD1_YEAST
Multiple RNA-binding domain-containing protein 1
Saccharomyces
<M><S><R><I><I><V><K><G><L><P><V><Y><L><T><D><D><N><L><R><E><H><F><T><K><R><L><R><Q><K><H><S><H><Q><A><V><N><G><S><G><P><D><L><I><T><D><V><K><I><L><R><D><R><N><G><E><S><R><R><F><G><F><I><G><Y><R><N><E><E><D><A><F><D><A><V><E><Y><F><N><G><S><F><I><N><T><S><K><I><E><V><S><M><A><K><S><F><A><D><P><R><V><P><Q><P><M><K><E><K...
Involved in pre-rRNA processing. Required for maintaining steady-state levels of 40S ribosomal subunit. Required for the initial processing of pre-rRNA at the A0 to A2 sites, leading to the processing of the 23S pre-rRNA intermediate to the 18S rRNA.<BOP>
Q06106
P80174
SODC_CARCR
Superoxide dismutase [Cu-Zn]
Caretta
<M><A><T><V><K><A><V><C><V><L><K><G><E><D><P><V><K><E><P><V><K><G><P><V><K><E><P><V><K><G><I><I><Y><F><E><Q><Q><G><N><G><P><V><T><L><S><G><S><I><T><G><L><T><E><G><K><H><G><F><H><V><H><E><F><G><D><N><T><N><G><C><T><S><A><G><A><H><F><N><P><P><G><K><N><H><G><G><P><Q><D><N><E><R><H><V><G><D><L><G><N><V><I><A><N><K><E><G><V...
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.<BOP>
P80174
B9KER1
RL21_CAMLR
50S ribosomal protein L21
Campylobacter
<M><Y><A><I><I><K><H><S><G><K><Q><Y><R><V><S><Q><G><D><E><L><K><L><D><R><F><E><A><E><V><K><S><S><V><E><V><S><E><V><L><A><V><C><D><K><E><L><K><V><G><A><P><F><V><A><G><A><K><V><V><L><E><V><I><A><H><G><K><D><K><K><V><V><I><Y><K><K><R><R><R><K><D><S><K><L><K><R><G><F><R><R><Q><F><T><R><V><R><V><V><D><I><K><A>
This protein binds to 23S rRNA in the presence of protein L20.<BOP>
B9KER1
Q8NSL2
PRPB2_CORGL
(2R,3S)-2-methylisocitrate lyase
Corynebacterium
<M><A><G><L><F><S><S><A><V><A><P><T><E><R><R><K><A><L><R><A><A><L><A><A><P><E><I><A><R><M><P><G><A><F><S><P><L><A><A><R><A><I><Q><E><A><G><F><E><G><V><Y><V><S><G><A><V><V><A><A><D><L><A><L><P><D><I><G><L><T><T><L><T><E><V><A><H><R><S><R><Q><I><A><R><V><T><D><L><P><V><L><V><D><A><D><T><G><F><G><E><P><M><S><A><A><R><T><V...
Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.<BOP>
Q8NSL2
Q81JW0
RPOE_BACAN
RNAP delta factor
Bacillus cereus group
<M><D><F><K><Q><Y><S><P><E><E><L><K><E><C><S><M><I><E><V><V><H><S><V><L><G><D><K><R><Q><A><T><T><F><N><E><L><V><Q><E><I><A><Q><V><L><G><L><S><Q><E><Q><V><N><A><K><I><A><Q><F><Y><T><D><L><N><I><D><G><R><F><I><N><L><G><E><N><R><W><G><L><R><S><W><Y><P><Y><E><Q><I><D><E><E><I><L><P><Q><P><K><P><K><K><K><R><K><V><E><D><D><G...
Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.<BOP>
Q81JW0
Q9HIC2
PGMI_THEAC
Phosphomannose isomerase
Thermoplasma
<M><L><R><S><H><C><M><E><F><S><E><E><L><K><T><L><K><D><Q><V><R><F><D><G><S><F><R><T><G><T><F><S><N><I><V><I><A><G><M><G><G><S><G><I><A><G><R><I><F><S><E><M><Y><S><A><K><P><V><F><V><C><D><D><Y><H><I><P><E><F><V><D><G><N><T><E><F><I><A><V><S><Y><S><G><N><T><E><E><T><L><S><A><A><E><E><A><I><K><K><G><A><K><V><H><A><I><T><S...
Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.<BOP>
Q9HIC2
B1IND6
CLPX_CLOBK
ATP-dependent Clp protease ATP-binding subunit ClpX
Clostridium
<M><S><K><L><D><E><K><K><Q><L><K><C><S><F><C><G><K><T><Q><D><Q><V><R><R><L><I><A><G><P><G><V><Y><I><C><D><E><C><I><E><L><C><S><E><I><I><N><D><E><F><E><D><D><I><Q><V><D><L><T><S><L><P><K><P><T><E><I><K><T><Y><L><D><Q><Y><V><I><G><Q><E><D><A><K><K><S><L><S><V><A><V><Y><N><H><Y><K><R><I><N><S><N><T><N><N><D><D><V><E><L><Q...
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP>
B1IND6
Q5HEU3
CPFC_STAAC
Coproporphyrin III ferrochelatase
Staphylococcus
<M><T><K><K><M><G><L><L><V><M><A><Y><G><T><P><Y><K><E><S><D><I><E><P><Y><Y><T><D><I><R><H><G><K><R><P><S><E><E><E><L><Q><D><L><K><D><R><Y><E><F><I><G><G><L><S><P><L><A><G><T><T><D><D><Q><A><D><A><L><V><S><A><L><N><K><A><Y><A><D><V><E><F><K><L><Y><L><G><L><K><H><I><S><P><F><I><E><D><A><V><E><Q><M><H><N><D><G><I><T><E><A...
Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.<BOP>
Q5HEU3
Q38X88
AROE_LATSS
Shikimate dehydrogenase (NADP(+))
Latilactobacillus
<M><I><S><G><Y><T><A><L><Y><G><L><I><A><H><P><A><Q><H><S><L><S><P><F><I><H><N><T><G><F><H><Q><I><Q><M><D><A><R><Y><A><V><F><D><S><Q><A><T><P><A><A><I><T><S><A><I><K><T><L><G><I><R><G><V><N><L><S><M><P><Y><K><Q><S><L><V><P><L><V><D><N><L><T><S><T><A><K><L><V><G><A><I><N><T><I><K><N><E><A><G><R><L><T><A><T><N><T><D><G><D...
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP>
Q38X88
B5Z937
MIAA_HELPG
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Helicobacter
<M><D><A><E><I><F><S><L><D><S><L><S><I><Y><K><D><I><N><I><A><S><A><K><P><S><L><K><E><R><K><N><I><K><H><Y><A><L><D><Y><L><N><I><D><E><K><N><N><A><Q><L><F><K><T><L><L><E><D><A><M><R><V><S><S><K><E><I><L><L><I><V><G><G><S><S><F><Y><L><K><S><I><L><E><G><L><S><D><T><P><K><I><S><G><E><E><V><V><K><I><E><R><E><I><A><T><L><S><N...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
B5Z937
Q5DT36
KLRI2_MOUSE
Killer cell lectin-like receptor subfamily I member 2
Mus
<M><H><K><K><K><H><I><K><H><G><T><N><K><Q><E><I><I><N><I><G><T><K><S><P><T><F><Q><E><K><Q><R><P><S><K><T><D><Q><R><S><T><V><W><R><E><E><Q><K><K><Q><E><L><K><V><H><R><I><F><H><P><Q><P><R><T><G><F><D><V><G><K><G><I><D><P><W><L><T><T><W><Q><M><I><T><V><I><L><A><T><L><C><I><I><L><V><T><K><V><G><F><L><I><P><S><L><F><S><K><G...
Lectin-like receptor for natural killer (NK) cells. Heterodimer formation with KLRE1 mediates NK cell cytolytic activity.<BOP>
Q5DT36
F4I366
NRPA2_ARATH
Nuclear RNA polymerase A2
Arabidopsis
<M><V><V><N><A><K><D><S><T><V><P><T><M><E><D><F><K><E><L><H><N><L><V><T><H><H><I><E><S><F><D><Y><M><T><L><K><G><L><D><V><M><F><N><R><I><K><P><V><S><V><Y><D><P><N><T><E><N><E><L><S><I><W><L><E><N><P><L><V><F><A><P><Q><K><E><S><F><K><S><T><S><R><K><E><P><L><L><P><F><E><C><R><Q><A><K><I><S><Y><T><G><T><F><M><A><D><V><C><F...
Essential for the completion of the three rounds of mitosis in female megaspores required for the development of mature gametophytes.<BOP>
F4I366
Q8WHY0
RK23_PSINU
50S ribosomal protein L23, chloroplastic
Psilotum
<M><N><E><I><K><N><Q><I><I><T><E><K><T><I><R><L><L><Q><K><N><Q><Y><T><F><N><V><D><S><K><L><T><K><T><K><I><K><D><W><I><E><R><F><F><D><V><K><V><K><S><I><N><S><L><R><S><P><R><K><K><S><Q><K><R><L><P><Q><T><S><L><N><D><K><R><M><I><I><T><L><K><P><E><Y><S><I><P><L><F><I><N><E>
Binds to 23S rRNA.<BOP>
Q8WHY0
Q5HC98
SSRP_EHRRW
Small protein B
Ehrlichia
<M><D><I><I><I><E><N><R><K><V><R><F><N><Y><F><I><I><Q><E><F><D><A><G><I><V><L><I><G><S><E><V><K><S><L><R><Q><R><K><V><S><I><A><E><S><Y><V><T><E><R><N><M><E><L><W><L><C><N><L><H><I><S><E><Y><T><Q><A><N><T><K><N><H><N><P><T><R><P><R><K><L><L><L><K><K><K><Q><I><Y><K><I><S><G><N><M><K><N><D><G><F><T><V><V><P><L><F><L><Y><F...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
Q5HC98
A5FR86
RNH2_DEHMB
Ribonuclease HII
Dehalococcoides
<M><P><A><T><V><I><C><P><S><R><A><E><E><K><L><L><R><K><Q><G><F><I><L><I><A><G><L><D><E><A><G><R><G><C><L><A><G><P><V><V><A><G><A><V><I><M><P><P><R><L><K><G><D><W><V><E><M><V><R><D><S><K><V><L><S><P><A><K><R><E><Y><L><Y><C><H><I><V><S><M><A><V><T><F><G><V><G><A><V><D><N><E><Q><I><D><S><M><G><I><A><P><A><T><R><L><A><M><K...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
A5FR86
Q1GLQ5
PANC_RUEST
Pantoate-activating enzyme
unclassified Ruegeria
<M><T><P><P><I><L><R><R><L><D><D><L><R><A><L><R><R><D><W><M><K><K><G><D><T><L><G><L><V><P><T><M><G><A><L><H><A><G><H><L><S><L><V><E><A><A><K><A><A><C><D><H><V><V><V><T><I><F><V><N><P><K><Q><F><N><S><P><E><D><L><A><N><Y><P><R><T><E><H><E><D><A><Q><K><L><A><P><Y><G><V><D><A><I><Y><V><P><D><P><D><Q><I><Y><P><E><G><Y><A><T...
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP>
Q1GLQ5
Q9PPB0
NADE_CAMJE
NH(3)-dependent NAD(+) synthetase
Campylobacter
<M><D><W><Q><K><I><T><E><K><M><C><D><F><I><Q><E><K><V><K><N><S><Q><S><Q><G><V><V><L><G><L><S><G><G><I><D><S><A><L><V><A><T><L><C><K><R><A><L><K><E><N><V><F><A><L><L><M><P><T><Q><I><S><N><K><A><N><L><E><D><A><L><R><L><C><A><D><L><N><L><E><Y><K><I><I><E><I><Q><S><I><L><D><A><F><I><K><Q><S><E><N><T><T><L><V><S><L><G><N><F...
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.<BOP>
Q9PPB0
Q5PQM9
KMCP1_RAT
Solute carrier family 25 member 30
Rattus
<M><S><A><L><N><W><K><P><F><V><Y><G><G><L><A><S><I><T><A><E><C><G><T><F><P><I><D><L><T><K><T><R><L><Q><I><Q><G><Q><T><N><D><A><K><F><R><E><I><R><Y><R><G><M><L><H><A><L><M><R><I><G><R><E><E><G><L><R><A><L><Y><S><G><I><A><P><A><M><L><R><Q><A><S><Y><G><T><I><K><I><G><T><Y><Q><S><L><K><R><L><A><V><E><R><P><E><D><E><T><L><L...
Probable transporter.<BOP>
Q5PQM9
B4JII0
SPAST_DROGR
Spastin
Hawaiian Drosophila
<M><V><R><T><K><N><Q><S><S><S><S><S><A><S><S><S><T><K><S><P><V><K><I><S><G><G><T><T><N><R><S><R><S><C><S><D><A><L><I><D><D><G><N><S><K><S><S><S><K><P><T><S><N><N><R><Q><R><T><T><T><N><N><N><T><T><A><I><T><T><T><P><G><S><S><P><D><N><D><D><D><D><T><T><T><T><D><A><D><L><T><P><T><S><G><N><A><P><R><G><G><N><S><S><V><H><K><Q...
ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in a...
B4JII0
Q6G7H4
PDP_STAAS
Pyrimidine-nucleoside phosphorylase
Staphylococcus
<M><R><M><I><D><I><I><E><K><K><R><D><G><H><T><L><T><T><E><E><I><N><F><F><I><D><G><Y><V><K><G><D><I><P><D><Y><Q><A><S><S><L><A><M><A><I><Y><F><Q><D><M><N><D><D><E><R><A><A><L><T><M><A><M><V><N><S><G><D><M><I><D><L><S><D><I><K><G><V><K><V><D><K><H><S><T><G><G><V><G><D><T><T><T><L><V><L><A><P><L><V><A><A><V><D><V><P><V><A...
Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.<BOP>
Q6G7H4
Q117Z4
UREF_TRIEI
Urease accessory protein UreF
Trichodesmium
<M><I><N><S><D><I><S><E><Q><L><A><L><M><Q><L><S><D><S><F><F><P><T><G><S><F><T><F><S><H><G><L><E><T><L><V><Q><T><G><K><I><Q><S><Q><P><E><I><L><Y><F><L><Q><I><L><L><R><N><K><V><G><V><S><D><V><V><A><L><I><H><S><Y><R><G><C><K><N><G><D><I><E><A><V><R><V><A><D><R><M><L><F><V><Q><T><A><I><A><K><N><R><E><T><Q><R><Q><S><G><R><A...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
Q117Z4
B0RED7
ATPD_CLAMS
F-type ATPase subunit delta
Clavibacter
<M><G><S><A><S><R><A><S><L><D><S><A><R><R><V><L><A><E><L><G><G><V><D><L><S><T><A><G><Q><L><L><G><A><G><R><A><I><G><G><S><T><H><L><L><S><A><L><A><D><T><G><I><A><P><E><V><K><H><S><I><V><D><R><V><F><G><A><T><V><Q><E><P><T><L><R><V><L><R><A><V><V><D><G><R><W><S><S><H><D><E><L><L><A><G><I><E><E><L><G><I><R><A><V><A><I><S><A...
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.<BOP>
B0RED7
Q49XD2
GUAC_STAS1
Guanosine 5'-monophosphate oxidoreductase
Staphylococcus
<M><K><I><F><D><Y><E><D><I><Q><L><V><P><N><K><C><I><V><N><S><R><S><E><C><D><T><T><I><Q><F><G><P><R><S><F><K><L><P><V><V><P><A><N><M><Q><T><V><M><N><E><T><L><A><E><W><F><A><E><N><D><Y><F><Y><I><M><H><R><F><D><E><E><G><R><I><P><F><I><K><K><M><Q><E><K><G><L><F><A><S><I><S><V><G><V><K><E><R><E><F><G><F><V><E><S><L><A><A><E...
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.<BOP>
Q49XD2
Q5HGQ4
BSHC_STAAC
Putative cysteine ligase BshC
Staphylococcus
<M><D><C><K><V><V><S><L><N><E><K><D><Q><F><I><P><K><I><K><S><S><D><P><V><I><T><G><L><F><Q><Y><D><A><A><Q><Q><T><S><F><E><K><R><M><S><K><E><N><N><G><R><E><A><A><L><A><N><V><I><R><E><Y><M><S><D><L><K><L><S><S><E><Q><E><L><N><I><Q><H><L><A><N><G><S><K><V><V><I><G><G><Q><Q><A><G><L><F><G><G><P><L><Y><T><F><H><K><I><F><S><I...
Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.<BOP>
Q5HGQ4
P60322
NANO2_MOUSE
Nanos homolog 2
Mus
<M><D><L><P><P><F><D><M><W><R><D><Y><F><N><L><S><Q><V><V><M><D><I><I><Q><S><R><K><Q><R><Q><E><G><E><V><A><E><E><P><N><S><R><P><Q><E><K><S><E><Q><D><L><E><G><Y><P><G><C><L><P><T><I><C><N><F><C><K><H><N><G><E><S><R><H><V><Y><T><S><H><Q><L><K><T><P><E><G><V><V><V><C><P><I><L><R><H><Y><V><C><P><L><C><G><A><T><G><D><Q><A><H...
Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is requi...
P60322
B1YVM2
LEPA_BURA4
Ribosomal back-translocase LepA
Burkholderia cepacia complex
<M><D><H><I><R><N><F><S><I><I><A><H><I><D><H><G><K><S><T><L><A><D><R><I><I><Q><V><C><G><G><L><A><D><R><E><M><E><A><Q><V><L><D><S><M><D><I><E><R><E><R><G><I><T><I><K><A><Q><T><A><A><L><S><Y><R><A><R><D><G><K><V><Y><N><L><N><L><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><S><L><S><A><C><E><G><A><L><L><V><V><D><A><S><Q><G...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
B1YVM2
Q13VE3
DADA_PARXL
D-amino acid dehydrogenase
Paraburkholderia
<M><R><V><V><V><L><G><S><G><V><V><G><V><T><S><A><Y><Y><L><A><R><A><G><H><E><V><T><V><I><D><R><E><A><G><P><A><L><E><T><S><F><A><N><A><G><Q><I><S><P><G><Y><A><S><P><W><A><A><P><G><V><P><L><K><A><V><K><W><M><F><Q><K><H><A><P><L><A><I><R><L><D><G><T><Q><F><Q><L><Q><W><M><W><Q><M><L><Q><N><C><T><S><S><R><Y><A><V><N><K><G><R...
Oxidative deamination of D-amino acids.<BOP>
Q13VE3
C4K8Y6
DUT_HAMD5
dUTP pyrophosphatase
Candidatus Hamiltonella
<M><K><K><I><D><I><K><I><L><D><K><R><I><G><D><V><F><P><L><P><T><Y><T><T><S><G><S><A><G><L><D><L><R><V><C><T><Q><A><P><Q><H><L><S><P><G><E><T><R><L><L><P><T><G><L><A><V><H><I><A><D><P><H><L><A><A><M><I><L><P><R><S><G><L><G><H><K><N><G><I><V><L><G><N><L><V><G><L><I><D><S><D><Y><Q><G><E><L><M><L><S><V><W><N><R><S><Q><I><D...
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<BOP>
C4K8Y6
P61897
MDH_PECCC
Malate dehydrogenase
Pectobacterium
<L><R><R><K><P><G><M><D><R><S><D><L><F><N><V><N><A><G><I><V><R><N><L><V><E><Q><I><A><V><T><C><P><K><A><C><I><G><I><I><T><N><P><V><N><T><T><V><A><I><A><A><E><V><L><K><K><A><G><V><Y><D><K><N><K><L><F><G><V><T><T><L><D><I><I><R><S><N><T><F><V><A><E><L><K><G><K><Q><P><Q><D><I><N><V><P><V><I><G><G><H><S><G><V><T><I><L><P><L...
Catalyzes the reversible oxidation of malate to oxaloacetate.<BOP>
P61897
A0A0G2JMI3
HV692_HUMAN
Immunoglobulin heavy variable 1-69-2
Homo
<M><D><C><T><W><R><I><L><L><L><V><A><A><A><T><G><T><H><A><E><V><Q><L><V><Q><S><G><A><E><V><K><K><P><G><A><T><V><K><I><S><C><K><V><S><G><Y><T><F><T><D><Y><Y><M><H><W><V><Q><Q><A><P><G><K><G><L><E><W><M><G><L><V><D><P><E><D><G><E><T><I><Y><A><E><K><F><Q><G><R><V><T><I><T><A><D><T><S><T><D><T><A><Y><M><E><L><S><S><L><R><S...
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep...
A0A0G2JMI3
Q0VSM4
RL10_ALCBS
50S ribosomal protein L10
Alcanivorax
<M><P><L><N><L><E><D><K><R><A><I><V><A><S><V><N><A><V><A><A><E><A><L><S><A><V><V><A><D><Y><R><G><L><T><V><S><Q><M><T><E><L><R><S><K><A><R><E><T><G><V><Y><L><K><V><V><R><N><T><L><A><K><F><A><V><K><D><T><E><F><E><C><L><N><D><A><L><V><G><P><T><V><L><A><F><S><K><D><D><P><G><A><A><A><R><L><I><K><D><F><A><K><D><H><D><A><L><E...
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.<BOP>
Q0VSM4
Q609K0
QUEC_METCA
Queuosine biosynthesis protein QueC
Methylococcus
<M><K><P><A><V><V><L><L><S><G><G><L><D><S><A><T><T><L><A><I><A><R><R><E><G><F><A><C><H><A><M><S><F><D><Y><G><Q><R><H><G><A><E><L><K><A><A><R><R><L><A><Q><S><L><G><A><I><E><H><K><T><V><H><I><G><L><D><A><I><G><G><S><A><L><T><D><L><R><I><A><V><P><D><H><P><Q><N><G><I><P><V><T><Y><V><P><A><R><N><T><V><F><L><S><F><A><L><G><W...
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).<BOP>
Q609K0
Q3JAS2
TTCA_NITOC
tRNA 2-thiocytidine biosynthesis protein TtcA
Nitrosococcus
<M><N><K><Q><S><R><K><A><Q><Y><N><A><N><K><L><Q><K><R><L><R><R><L><V><G><Q><A><I><E><T><F><N><M><I><E><D><G><D><R><L><M><V><C><L><S><G><G><K><D><S><Y><A><L><L><D><I><L><L><S><L><Q><K><H><A><P><V><K><F><D><L><I><A><V><N><L><D><Q><K><Q><P><G><F><P><E><H><V><L><P><H><Y><L><E><S><L><G><V><S><Y><R><I><V><E><Q><D><T><Y><S><V...
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP>
Q3JAS2
B0BAL3
MURD_CHLTB
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Chlamydia
<M><G><L><E><R><V><V><V><I><G><L><G><V><S><G><R><S><I><A><R><F><L><A><Q><K><G><V><C><V><L><G><V><D><K><S><L><H><A><L><Q><N><C><P><Y><I><Q><E><K><Y><L><E><N><E><E><F><P><S><Q><V><D><Y><V><V><R><S><P><G><V><S><K><E><H><P><W><V><Q><A><A><I><A><S><H><I><P><V><M><T><D><I><Q><L><A><F><Q><T><E><K><F><T><E><R><E><S><L><A><I><T...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
B0BAL3
Q3SPN4
LGT_NITWN
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Nitrobacter
<M><F><L><L><I><T><Y><P><V><F><D><P><V><A><I><S><L><G><P><I><A><I><R><W><Y><A><L><A><Y><I><G><G><I><M><L><G><W><L><Y><A><R><A><L><L><R><S><E><K><L><W><G><G><P><A><P><I><S><V><V><Q><L><D><D><F><I><L><W><V><T><I><A><I><I><V><G><G><R><V><G><Y><V><L><F><Y><N><P><D><Y><F><I><R><Y><P><A><Q><I><F><Q><L><W><N><G><G><M><S><F><H...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
Q3SPN4
Q8J0F3
MLCE_PENCI
Compactin biosynthesis protein E
Penicillium
<M><S><E><P><L><P><P><K><E><G><E><P><R><P><Q><K><E><E><S><Q><N><D><T><L><E><A><T><E><S><K><S><Q><H><I><T><G><L><K><L><G><L><V><V><A><S><V><T><F><V><A><F><L><M><L><L><D><M><S><I><I><V><T><A><I><P><H><I><T><S><E><F><H><S><L><N><D><V><G><W><Y><G><S><A><Y><L><L><A><N><C><A><L><Q><P><L><A><G><K><L><Y><T><L><L><G><L><K><Y><T...
Efflux pump; part of the gene cluster that mediates the biosynthesis of compactin, also known as mevastatin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase .<BOP>
Q8J0F3
B7IGA0
RL11_THEAB
50S ribosomal protein L11
Thermosipho
<M><A><K><K><V><V><A><Q><V><R><L><Q><L><E><A><G><K><A><T><P><A><P><P><V><G><P><A><L><G><Q><R><G><V><N><L><M><E><F><C><K><K><F><N><A><A><T><A><D><K><A><G><M><I><I><P><V><I><I><T><V><Y><E><D><R><S><F><T><F><I><T><K><T><P><P><A><S><F><L><L><K><K><A><A><K><L><N><S><G><S><Q><E><P><K><R><K><M><V><G><K><V><T><R><D><Q><I><K><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
B7IGA0
B5E9D0
NDK_CITBB
Nucleoside-2-P kinase
Citrifermentans
<M><E><R><T><F><A><I><I><K><P><D><A><V><E><R><N><V><T><G><K><V><L><A><M><I><E><E><G><G><F><K><I><V><G><M><K><K><I><R><L><S><K><C><Q><A><E><G><F><Y><Y><V><H><K><E><R><P><F><F><G><D><L><C><A><F><M><S><R><G><P><V><I><A><L><V><L><E><K><E><N><A><I><A><D><W><R><G><L><M><G><A><T><N><P><A><N><A><E><A><G><T><I><R><K><A><L><G><V...
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP>
B5E9D0
O43102
CBF5_ASPFU
Small nucleolar RNP protein cbf5
Aspergillus subgen. Fumigati
<M><A><V><S><V><T><K><E><E><M><D><Y><T><I><K><P><E><A><G><A><S><N><I><S><T><E><D><W><P><L><L><L><K><N><Y><D><K><L><M><V><R><T><G><H><F><T><P><I><P><A><G><C><S><P><L><K><R><D><L><K><S><Y><I><S><S><G><V><I><N><L><D><K><P><S><N><P><S><S><H><E><V><V><A><W><M><K><R><I><L><R><A><E><K><T><G><H><S><G><T><L><D><P><K><V><T><G><C...
Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation...
O43102
A9KSS1
HPRK_LACP7
HPr(Ser) kinase/phosphorylase
Lachnospiraceae
<M><Y><T><V><E><L><G><K><L><V><E><K><M><N><L><E><N><C><T><P><E><I><D><I><S><S><I><Q><I><T><Q><P><D><V><N><R><P><A><L><Q><L><T><G><F><F><D><Y><F><D><S><D><R><V><Q><I><I><G><N><V><E><H><A><Y><M><Q><K><M><E><K><D><H><G><L><G><I><M><K><K><L><M><S><F><K><M><P><C><I><V><F><C><R><G><I><E><V><S><E><D><F><K><E><V><A><I><E><E><G...
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphor...
A9KSS1
Q98HV6
PTH_RHILO
Peptidyl-tRNA hydrolase
Mesorhizobium
<M><L><V><F><A><G><L><G><N><P><G><A><K><Y><A><D><N><R><H><N><V><G><F><M><A><A><D><A><I><A><R><R><H><S><F><S><P><W><S><K><K><F><Q><G><L><I><A><E><G><T><I><A><G><E><K><I><I><L><I><K><P><Q><T><F><M><N><L><S><G><Q><S><V><G><E><A><L><R><F><Y><K><L><E><L><S><A><L><T><V><F><Y><D><E><I><D><L><A><E><G><K><L><R><I><K><T><G><G><G...
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP>
Q98HV6
Q4JV87
LEXA_CORJK
LexA repressor
Corynebacterium
<M><S><I><D><E><S><S><D><N><P><T><P><R><P><K><L><G><R><P><P><K><S><E><A><D><K><R><A><E><K><E><A><Q><K><D><G><K><K><P><A><L><S><T><R><Q><R><R><I><L><E><V><I><R><D><S><T><I><I><R><G><Y><P><P><S><I><R><E><I><A><D><A><V><G><L><H><S><T><S><S><V><S><Y><H><L><T><Q><L><E><K><R><G><Y><L><R><R><D><G><K><R><P><R><A><V><D><V><R><A...
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair...
Q4JV87
Q71XF4
CPFC_LISMF
Coproporphyrin III ferrochelatase
Listeria
<M><T><K><K><V><G><L><L><V><M><A><Y><G><T><P><Y><K><D><E><D><I><E><R><Y><Y><T><D><I><R><H><G><H><K><P><S><E><E><M><I><A><D><L><R><G><R><Y><H><A><I><G><G><L><S><P><L><A><K><I><T><E><A><Q><A><Y><G><L><E><K><A><L><N><E><S><Q><D><E><V><E><F><K><A><Y><I><G><L><K><H><I><E><P><F><I><E><D><A><V><E><A><M><H><K><D><G><I><E><E><A...
Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.<BOP>
Q71XF4
Q01854
RDXA_CERS4
Protein RdxA
Cereibacter
<M><S><E><P><L><Y><A><P><R><T><P><I><F><P><R><Q><I><S><G><A><F><R><T><A><K><W><W><I><L><A><V><S><L><G><I><Y><L><L><T><P><W><L><R><W><D><R><G><P><N><L><P><D><Q><A><V><L><I><D><I><A><G><R><R><F><F><L><F><G><I><Q><I><W><P><H><E><F><Y><F><V><A><G><L><L><I><M><A><G><L><G><L><F><L><F><T><S><A><A><G><R><V><W><C><G><Y><A><C><P...
Predicted to be involved in a redox process.<BOP>
Q01854
Q6G4G5
PURA_BARHE
IMP--aspartate ligase
Bartonella
<M><A><N><V><V><V><V><G><T><Q><W><G><D><E><G><K><G><K><I><V><D><W><L><S><E><R><A><D><I><I><V><R><Y><Q><G><G><H><N><A><G><H><T><L><V><V><N><G><V><N><Y><K><L><S><L><L><P><S><G><L><V><R><G><K><L><S><I><I><G><N><G><V><V><V><D><P><H><H><F><V><V><E><L><K><K><L><R><D><Q><G><V><K><I><V><P><E><I><L><R><I><A><E><N><A><P><L><I><L...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
Q6G4G5
A8FYV3
DPO4_SHESH
DNA polymerase IV
Shewanella
<M><K><K><I><I><H><I><D><M><D><C><Y><F><A><A><V><E><M><R><D><F><P><E><L><R><G><K><P><I><A><V><G><G><R><S><D><R><R><G><V><I><S><T><C><N><Y><E><A><R><K><F><G><V><R><S><A><M><A><S><G><Y><A><L><K><L><C><P><D><L><I><L><V><P><G><R><M><S><V><Y><K><E><V><S><A><Q><I><R><E><V><F><S><H><Y><T><D><L><I><E><P><L><S><L><D><E><A><Y><L...
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in...
A8FYV3
A0QVH7
DXR_MYCS2
2-C-methyl-D-erythritol 4-phosphate synthase
Mycolicibacterium
<M><T><T><S><A><A><S><G><E><P><G><R><Q><R><V><L><I><L><G><S><T><G><S><I><G><T><Q><A><L><E><V><I><A><A><N><P><D><R><F><E><V><V><G><L><A><A><G><G><G><N><P><E><L><L><A><A><Q><R><A><Q><T><G><V><A><A><V><A><V><A><D><P><A><A><A><E><A><V><G><D><V><R><Y><S><G><P><D><A><V><T><R><L><V><E><D><T><E><A><D><V><V><L><N><A><L><V><G><A...
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
A0QVH7
C1CZJ9
RL21_DEIDV
50S ribosomal protein L21
Deinococcus
<M><F><A><I><I><Q><T><G><G><K><Q><Y><R><V><Q><E><G><D><V><I><R><V><E><N><L><K><G><E><A><G><D><K><L><D><L><T><P><L><F><V><G><G><D><Q><A><L><F><G><D><A><V><S><N><F><V><V><N><A><E><V><V><E><H><G><R><G><P><K><I><Y><I><R><K><Y><K><S><G><V><Q><Y><R><R><R><T><G><H><R><Q><D><Y><T><A><I><K><I><L><G><I><K><G>
This protein binds to 23S rRNA in the presence of protein L20.<BOP>
C1CZJ9
Q1BZG3
MURG_BURCA
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Burkholderia cepacia complex
<M><T><A><S><Q><R><T><L><M><V><M><A><G><G><T><G><G><H><V><F><P><G><L><A><V><A><H><R><M><E><A><A><G><W><R><V><V><W><L><G><N><P><A><G><M><E><A><T><L><V><P><K><H><G><I><P><M><E><Y><V><R><F><G><G><L><R><G><K><G><L><K><T><K><L><T><L><P><V><N><L><L><R><A><C><W><Q><S><L><G><A><L><R><R><V><R><P><D><V><V><L><G><M><G><G><Y><I><T...
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).<BOP>
Q1BZG3
Q96BX8
MOB3A_HUMAN
Mps one binder kinase activator-like 2A
Homo
<M><S><N><P><F><L><K><Q><V><F><N><K><D><K><T><F><R><P><K><R><K><F><E><P><G><T><Q><R><F><E><L><H><K><K><A><Q><A><S><L><N><A><G><L><D><L><R><L><A><V><Q><L><P><P><G><E><D><L><N><D><W><V><A><V><H><V><V><D><F><F><N><R><V><N><L><I><Y><G><T><I><S><D><G><C><T><E><Q><S><C><P><V><M><S><G><G><P><K><Y><E><Y><R><W><Q><D><E><H><K><F...
May regulate the activity of kinases.<BOP>
Q96BX8
Q9SJJ5
CKS2_ARATH
Cyclin-dependent kinases regulatory subunit 2
Arabidopsis
<M><G><Q><I><Q><Y><S><D><K><Y><F><D><D><T><F><E><Y><R><H><V><V><L><P><P><E><V><A><K><L><L><P><K><N><R><I><L><S><E><S><E><W><R><A><I><G><V><Q><Q><S><R><G><W><V><H><Y><A><I><H><R><P><E><P><H><I><M><L><F><R><R><P><L><N><Y><Q><Q><E><H><Q><A><Q><I><A><K>
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.<BOP>
Q9SJJ5
A6VC62
HEM1_PSEA7
Glutamyl-tRNA reductase
Pseudomonas
<M><A><F><I><A><L><G><I><N><H><K><T><A><S><V><A><V><R><E><R><V><A><F><T><P><E><Q><M><V><E><A><L><Q><Q><L><C><R><L><T><T><S><R><E><A><A><I><L><S><T><C><N><R><S><E><L><Y><L><E><I><D><H><P><T><A><D><D><V><L><A><W><L><A><D><Y><H><R><L><T><L><D><E><L><R><A><C><A><Y><V><H><Q><D><E><D><A><V><R><H><M><M><R><V><A><S><G><L><D><S...
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).<BOP>
A6VC62
A7I3J2
DCD_CAMHC
Deoxycytidine triphosphate deaminase
Campylobacter
<M><G><L><K><S><D><K><W><I><R><E><Q><S><I><K><N><G><M><I><T><P><F><C><E><E><N><M><G><V><G><V><V><S><Y><G><L><S><S><Y><G><Y><D><I><R><V><A><D><E><F><K><I><F><T><N><V><G><G><T><V><V><D><P><K><N><F><D><E><K><N><I><V><D><F><K><G><D><V><C><I><V><P><P><N><S><F><A><L><A><R><T><I><E><Y><F><K><M><P><R><D><V><L><A><I><C><L><G><K...
Catalyzes the deamination of dCTP to dUTP.<BOP>
A7I3J2
B5XNX1
MENH_KLEP3
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
Klebsiella
<M><T><L><S><A><A><V><D><N><G><Q><S><G><Y><P><W><L><V><F><L><H><G><F><S><G><D><R><D><E><W><R><E><V><G><D><A><F><P><A><W><P><R><L><Y><L><D><L><P><G><H><G><G><S><A><D><I><A><V><Q><D><F><A><G><V><N><T><L><L><L><A><T><L><N><S><Y><N><I><L><N><Y><W><L><I><G><Y><S><L><G><G><R><V><A><M><N><F><A><C><Q><P><R><A><G><L><R><G><L><I...
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).<BOP>
B5XNX1
P28050
FETA_GORGO
Alpha-fetoglobulin
Gorilla
<M><K><W><V><E><S><I><F><L><I><F><L><L><N><F><T><E><S><R><T><L><H><R><N><E><Y><G><I><A><S><I><L><D><S><Y><Q><C><T><A><E><I><S><L><A><D><L><A><T><I><F><F><A><Q><F><V><Q><E><A><T><Y><K><E><V><S><K><M><V><K><D><A><L><T><A><I><E><K><P><T><G><D><E><Q><S><A><G><C><L><E><N><Q><L><P><A><F><L><E><E><L><C><H><E><K><E><I><L><E><K...
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.<BOP>
P28050
P07105
FANB_ECOLX
Fimbrial adhesin K99 B protein
Escherichia
<M><Y><I><D><N><Y><L><I><M><R><K><I><N><M><E><E><T><I><L><S><L><T><S><Y><Q><L><R><P><G><K><V><D><K><K><Q><F><V><L><L><I><D><V><S><S><I><R><S><Y><K><V><I><N><A><L><E><D><Y><F><V><N><G><K><N><R><K><E><I><C><D><N><H><K><I><N><Q><G><Y><L><S><L><K><I><R><E><L><Q><D><I><S><L><R><I><Y><N><I><S><H><C><I>
Trans-acting protein involved in the regulation of the biogenesis of K99 fimbriae (FanC).<BOP>
P07105
Q8ZZZ0
QUEE_PYRAE
Archaeosine biosynthesis protein QueE
Pyrobaculum
<M><S><A><T><P><R><V><R><V><L><E><I><F><A><S><L><Q><G><E><G><I><N><L><G><R><P><A><V><F><V><R><L><A><G><C><P><I><R><C><I><Y><C><D><T><K><Y><S><W><D><F><N><A><G><V><E><M><G><V><E><E><I><V><A><K><A><L><A><L><S><V><V><G><H><V><V><V><T><G><G><E><P><L><I><W><Q><R><R><G><L><E><E><L><A><C><A><L><R><A><L><G><S><V><E><V><E><T><S...
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.<BOP>
Q8ZZZ0
P53565
CUX1_RAT
CDP/Cux p110
Rattus
<M><A><A><N><V><G><S><M><F><Q><Y><W><K><R><F><D><L><Q><Q><L><Q><R><E><L><D><A><T><A><T><V><L><A><N><R><Q><D><E><S><E><Q><S><R><K><R><L><I><E><Q><S><R><E><F><K><K><N><T><P><E><D><L><R><K><Q><V><A><P><L><L><K><S><F><Q><G><E><I><D><A><L><S><K><R><S><K><E><A><E><A><A><F><L><T><V><Y><K><R><L><I><D><V><P><D><P><V><P><A><L><D...
Plays a role in cell cycle progression, in particular at the G1/S transition. As cells progress into S phase, a fraction of CUX1 molecules is proteolytically processed into N-terminally truncated proteins of 110 kDa. While CUX1 only transiently binds to DNA and carries the CCAAT-displacement activity, CDP/Cux p110 make...
P53565
A8GVL0
RNPA_RICB8
Protein C5
belli group
<M><F><I><T><S><L><K><N><Q><K><E><F><E><L><I><N><K><L><G><K><K><F><H><E><K><Y><F><I><L><V><I><A><K><N><I><P><K><I><F><L><E><S><K><Y><N><I><F><L><G><I><K><V><S><K><K><L><N><K><K><A><V><V><R><N><K><I><K><R><R><I><K><H><L><I><R><L><I><C><N><N><S><N><L><K><K><L><A><M><I><I><I><P><R><K><G><F><D><T><A><D><F><S><V><L><N><H><E...
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz...
A8GVL0
O08451
ACNA_MYCAV
RNA-binding protein
Mycobacterium avium complex (MAC)
<M><Q><D><K><R><T><V><K><V><G><T><V><A><D><T><A><V><G><G><R><T><K><S><L><G><V><E><V><T><D><S><V><N><S><F><G><A><R><N><R><V><K><V><G><D><K><S><Y><Q><I><Y><R><L><D><A><V><P><N><T><E><K><L><P><Y><S><L><K><V><L><A><E><N><L><L><R><N><E><D><G><S><N><I><T><K><D><H><I><E><A><I><A><N><W><D><P><K><A><G><A><S><I><E><I><Q><Y><T><P...
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. The apo form of AcnA functions as a RNA-...
O08451
B5EZJ2
RBN_SALA4
Ribonuclease Z homolog
Salmonella
<M><E><L><I><F><L><G><T><S><A><G><V><P><T><R><S><R><N><V><T><A><I><L><L><H><L><Q><H><P><T><Q><P><G><V><W><L><F><D><C><G><E><G><T><Q><H><Q><M><L><N><T><A><F><H><P><G><K><L><E><R><I><F><I><S><H><L><H><G><D><H><L><F><G><L><P><G><L><L><C><S><R><S><M><A><G><N><P><H><P><L><T><V><Y><G><P><Q><G><V><R><E><F><I><A><T><T><L><R><L...
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.<BOP>
B5EZJ2
Q3C1I3
PSBC_NICSY
Protein CP-43
Nicotiana
<M><E><T><L><F><N><G><T><L><A><L><A><G><R><D><Q><E><T><T><G><F><A><W><W><A><G><N><A><R><L><I><N><L><S><G><K><L><L><G><A><H><V><A><H><A><G><L><I><V><F><W><A><G><A><M><N><L><F><E><V><A><H><F><V><P><E><K><P><M><Y><E><Q><G><L><I><L><L><P><H><L><A><T><L><G><W><G><V><G><P><G><G><E><V><I><D><T><F><P><Y><F><V><S><G><V><L><H><L...
One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient sub...
Q3C1I3
Q98Q75
RSMH_MYCPU
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Mycoplasmopsis
<M><Q><L><H><K><P><V><L><L><K><D><V><I><E><N><L><E><I><N><P><E><G><I><Y><V><D><L><T><L><G><Y><A><G><H><S><S><E><I><L><K><K><L><S><S><K><G><K><L><I><G><F><D><Q><D><S><F><A><I><E><K><S><R><Q><R><L><S><Q><I><S><D><N><F><V><L><I><N><D><N><F><V><N><F><K><V><Y><L><D><K><M><N><I><S><F><V><D><G><F><L><L><D><L><G><V><S><S><V><Q...
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP>
Q98Q75
Q3ILP2
HSLO_PSET1
Heat shock protein 33 homolog
Pseudoalteromonas
<M><Q><Q><D><L><L><H><R><Y><L><F><D><N><L><D><V><R><G><E><L><V><Q><I><E><N><A><Y><N><E><M><I><A><N><H><N><Y><P><D><A><V><K><A><L><L><G><E><L><L><V><A><T><C><L><L><T><A><T><L><K><F><E><G><E><I><A><V><Q><L><Q><G><D><G><P><V><K><Y><A><V><I><N><G><D><D><K><Q><N><M><R><G><I><A><R><L><Q><S><E><V><T><G><S><T><V><K><E><L><I><G...
Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.<BOP>
Q3ILP2
Q6ECI4
ZN470_HUMAN
Chondrogenesis zinc finger protein 1
Homo
<M><K><S><Q><E><E><V><E><V><A><G><I><K><L><C><K><A><M><S><L><G><S><V><T><F><T><D><V><A><I><D><F><S><Q><D><E><W><E><W><L><N><L><A><Q><R><S><L><Y><K><K><V><M><L><E><N><Y><R><N><L><V><S><V><G><L><C><I><S><K><P><D><V><I><S><L><L><E><Q><E><K><D><P><W><V><I><K><G><G><M><N><R><G><L><C><P><D><L><E><C><V><W><V><T><K><S><L><S><L...
May be involved in transcriptional regulation.<BOP>
Q6ECI4
Q9AG20
MINC_NEIGO
Probable septum site-determining protein MinC
Neisseria
<M><M><V><Y><I><M><N><A><F><D><I><K><S><T><K><M><D><V><L><S><I><S><L><H><T><S><D><L><F><D><L><E><D><V><L><V><K><L><G><K><K><F><Q><E><S><G><V><V><P><F><V><L><D><V><Q><E><F><D><Y><P><E><S><L><D><L><A><A><L><V><S><L><F><S><R><H><G><M><Q><I><L><G><L><K><H><S><N><E><R><W><A><A><V><A><M><K><Y><H><L><L><F><C><L><S><H><S><E><N...
Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.<BOP>
Q9AG20
Q12GW4
RL16_POLSJ
50S ribosomal protein L16
unclassified Polaromonas
<M><L><Q><P><A><R><R><K><Y><R><K><E><Q><K><G><R><N><T><G><V><A><T><R><G><N><S><V><A><F><G><D><F><G><L><K><C><T><D><R><G><R><L><T><A><R><Q><I><E><A><A><R><R><A><I><S><R><H><V><K><R><G><G><R><I><W><I><R><V><F><P><D><K><P><I><S><Q><K><P><A><E><V><R><M><G><N><G><K><G><N><P><E><Y><Y><V><A><E><I><Q><P><G><K><I><V><F><E><I><V...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
Q12GW4
Q9CAK6
HIP15_ARATH
Heavy metal-associated isoprenylated plant protein 15
Arabidopsis
<M><I><V><W><M><G><V><Y><D><Q><R><S><K><G><K><I><T><K><S><I><S><D><L><P><G><I><H><S><S><Y><M><D><L><K><E><G><T><L><V><V><M><G><D><V><D><P><V><E><L><V><R><N><L><R><K><K><W><G><K><A><K><L><T><L><Y><V><P><Y><D><A><L><K><E><A><K><I><A><E><A><K><Q><K><R><E><E><I><E><R><E><A><L><Y><R><Y><N><R><E><I><R><D><I><F><N><D><K><E><E...
Probable heavy-metal-binding protein.<BOP>
Q9CAK6
Q4ULS3
DPO3B_RICFE
DNA polymerase III subunit beta
spotted fever group
<M><L><K><L><I><V><E><T><K><T><L><V><Q><S><L><G><F><A><S><S><V><V><E><K><R><N><V><I><P><E><Y><A><N><I><K><L><S><A><K><D><G><N><L><E><L><S><S><T><N><M><D><L><Y><L><S><Q><K><I><A><V><Q><V><V><S><E><G><E><L><T><V><S><T><K><T><L><N><D><I><V><R><K><L><P><D><S><E><L><T><L><T><D><L><G><T><T><G><L><E><I><K><G><K><N><C><K><F><N...
Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalyti...
Q4ULS3
B8GP00
RIMP_THISH
Ribosome maturation factor RimP
Thioalkalivibrio
<M><Q><L><K><A><L><L><E><P><L><V><T><R><M><G><Y><Q><L><W><G><M><E><F><R><V><A><K><H><S><A><L><L><R><L><F><I><D><S><E><Q><G><I><T><L><D><D><C><T><E><V><S><R><Q><V><S><A><L><M><D><V><E><D><P><I><Q><V><P><Y><T><L><E><V><S><S><P><G><V><D><R><P><L><F><E><A><G><Q><Y><A><R><Y><V><G><E><Q><V><R><V><R><T><Q><W><P><I><D><G><Q><R...
Required for maturation of 30S ribosomal subunits.<BOP>
B8GP00
A9M8W0
DXS_BRUC2
1-deoxyxylulose-5-phosphate synthase
Brucella
<M><S><R><P><S><T><P><L><L><D><K><A><P><T><P><D><R><L><R><A><L><P><E><Q><D><L><P><Q><L><A><E><E><L><R><T><E><L><I><D><A><V><S><T><T><G><G><H><L><G><A><G><L><G><V><V><E><L><T><V><A><L><H><H><V><F><N><T><P><Y><D><R><I><I><W><D><V><G><H><Q><A><Y><P><H><K><I><L><T><G><R><R><D><R><I><R><T><L><R><Q><A><G><G><L><S><G><F><T><K...
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP>
A9M8W0
A4STQ4
MNMG_AERS4
Glucose-inhibited division protein A
Aeromonas
<M><Q><Y><H><E><Q><F><D><V><I><V><V><G><G><G><H><A><G><T><E><A><A><T><A><A><A><R><M><G><L><N><T><L><L><L><T><H><N><I><D><T><L><G><H><M><S><C><N><P><A><I><G><G><I><G><K><G><H><L><V><K><E><V><D><A><L><G><G><I><M><A><R><A><T><D><L><A><G><I><Q><F><R><T><L><N><S><S><K><G><P><A><V><R><A><T><R><A><Q><A><D><R><L><L><Y><K><A><V...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
A4STQ4
Q2IY23
YIDD_RHOP2
Putative membrane protein insertion efficiency factor
Rhodopseudomonas
<M><H><S><R><L><P><T><H><A><A><D><L><L><Q><A><L><S><R><L><P><R><N><A><G><R><G><L><I><W><V><Y><R><H><S><F><S><A><L><V><G><S><N><C><R><H><L><P><T><C><S><Q><Y><G><D><E><A><I><G><R><F><G><L><W><A><G><G><W><M><T><L><A><R><L><I><R><C><N><P><Y><G><T><S><G><I><D><N><V><P><E><T><P><P><P><G><A><R><W><Y><L><P><W><R><Y><A><R><W><R...
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q2IY23
O26273
GLMS_METTH
L-glutamine--D-fructose-6-phosphate amidotransferase
Methanothermobacter
<M><C><G><I><V><A><C><I><L><K><D><G><S><A><A><P><V><L><L><E><C><V><R><R><L><E><Y><R><G><Y><D><S><V><G><I><A><T><S><D><P><M><I><R><I><K><K><D><S><G><K><I><D><E><V><D><A><E><L><D><L><A><D><L><P><G><T><M><G><I><A><H><V><R><W><A><T><H><G><L><P><T><A><E><N><A><H><P><H><T><D><C><S><G><E><I><A><V><V><H><N><G><I><I><E><N><Y><L...
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.<BOP>
O26273
Q5WJ30
DNLJ_ALKCK
Polydeoxyribonucleotide synthase [NAD(+)]
Alkalihalobacillus
<M><D><K><H><Q><A><E><K><R><L><K><E><L><R><L><L><L><E><D><Y><G><Y><H><Y><Y><V><L><D><T><P><K><V><P><D><S><E><Y><D><R><L><M><N><E><L><L><Q><L><E><A><D><Y><P><D><L><V><T><E><D><S><P><S><V><R><I><G><G><P><P><A><P><S><F><K><K><V><A><H><R><V><P><M><M><S><L><S><N><A><F><N><E><E><D><L><R><A><F><D><R><R><V><R><Q><A><V><G><E><H...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
Q5WJ30
Q6AQ14
ATPF_DESPS
F-type ATPase subunit b
Desulfotalea
<M><K><E><N><I><K><R><V><L><P><F><L><L><V><L><L><F><A><F><A><P><L><A><L><A><S><A><P><V><D><A><P><A><P><A><D><A><P><A><D><A><L><P><S><A><K><V><I><S><A><P><A><D><A><G><V><I><E><A><V><E><L><E><H><A><T><V><T><G><A><H><D><V><A><V><A><H><V><A><D><S><L><S><H><E><K><L><M><D><L><F><W><R><V><L><N><F><A><V><L><M><A><I><L><I><K><F...
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP>
Q6AQ14
B4TX73
AAEA_SALSV
p-hydroxybenzoic acid efflux pump subunit AaeA
Salmonella
<M><K><T><L><T><R><K><L><S><R><T><A><I><T><L><V><L><V><I><L><A><F><I><A><I><F><R><A><W><V><Y><Y><T><E><S><P><W><T><R><D><A><R><F><S><A><D><V><V><A><I><A><P><D><V><A><G><L><I><T><H><V><N><V><H><D><N><Q><L><V><K><K><D><Q><V><L><F><T><I><D><Q><P><R><Y><Q><K><A><L><A><E><A><E><A><D><V><A><Y><Y><Q><V><L><A><Q><E><K><R><Q><E...
Forms an efflux pump with AaeB.<BOP>
B4TX73
A3MPU3
HIS3_BURM7
Phosphoribosyl-AMP cyclohydrolase
pseudomallei group
<M><N><A><E><A><K><P><G><D><W><L><G><K><V><R><W><D><A><N><G><L><V><P><V><I><A><Q><D><A><A><T><N><D><V><L><M><F><A><W><M><N><R><D><A><L><A><K><T><I><E><L><K><R><A><V><Y><Y><S><R><S><R><Q><R><L><W><F><K><G><E><E><S><G><H><V><Q><H><V><H><E><V><R><L><D><C><D><E><D><V><V><L><L><K><V><E><Q><V><E><G><I><A><C><H><T><G><R><R><S...
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.<BOP>
A3MPU3
A2BNZ7
RL10_PROMS
50S ribosomal protein L10
Prochlorococcus
<M><G><R><T><L><E><N><K><Q><K><I><V><T><E><I><K><S><L><L><D><D><S><E><M><A><V><V><L><D><Y><K><G><L><T><I><K><E><M><S><D><L><R><S><R><L><Q><T><T><N><G><I><C><K><V><T><K><N><S><L><M><R><K><A><I><D><G><D><S><N><W><N><D><L><E><S><L><L><T><G><T><N><A><F><V><L><I><K><E><D><V><G><G><A><V><K><A><I><Q><S><F><Q><K><D><T><K><K><S...
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.<BOP>
A2BNZ7
Q10WQ4
CH602_TRIEI
Chaperonin-60 2
Trichodesmium
<M><A><K><R><I><I><Y><N><E><N><A><R><R><A><L><E><K><G><M><D><I><L><A><E><S><V><A><V><T><L><G><P><K><G><R><N><V><V><L><E><K><K><F><G><A><P><Q><I><V><N><D><G><V><T><I><A><K><E><I><E><L><E><D><H><V><E><N><T><G><V><S><L><I><R><Q><A><A><S><K><T><N><D><A><A><G><D><G><T><T><T><A><T><V><L><A><H><A><M><V><K><E><G><L><R><N><V><A...
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP>
Q10WQ4
Q6P2Y2
DAW1_XENTR
WD repeat-containing protein 69
Silurana
<M><R><L><K><R><F><L><L><R><Y><F><P><P><G><I><I><L><E><Y><E><K><G><G><E><L><K><T><K><A><I><D><L><L><E><L><S><P><T><T><D><V><D><L><V><V><E><E><I><Q><K><A><E><P><L><I><T><A><S><R><T><Q><Q><V><K><Q><L><I><L><R><L><Q><E><K><I><G><Q><Q><D><S><R><Q><F><Y><L><F><K><V><L><R><A><H><I><L><P><L><T><N><V><A><F><N><K><S><G><S><S><F...
May play a role in axonemal outer row dynein assembly.<BOP>
Q6P2Y2
A6U866
RL16_SINMW
50S ribosomal protein L16
Sinorhizobium
<M><L><Q><P><K><R><T><K><Y><R><K><Q><F><K><G><R><I><K><G><V><A><K><G><G><S><D><L><A><F><G><E><F><G><L><K><A><Q><E><P><N><R><V><N><A><R><E><I><E><A><A><R><R><A><I><T><R><H><M><K><R><A><G><R><V><W><I><R><V><F><P><D><V><P><V><T><A><K><P><T><E><V><R><M><G><K><G><K><G><S><V><E><Y><W><A><C><K><V><K><P><G><R><M><M><F><E><I><D...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
A6U866