accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
B5FPE5
MENC_SALDC
o-succinylbenzoic acid synthase
Salmonella
<M><R><S><A><Q><V><Y><R><W><Q><I><P><M><D><A><G><V><V><L><R><D><R><R><L><K><T><R><D><G><L><Y><V><C><L><R><D><G><E><R><E><G><W><G><E><I><S><P><L><P><G><F><S><Q><E><T><W><E><E><A><Q><T><A><L><L><T><W><V><N><D><W><L><Q><G><S><E><G><L><P><E><M><P><S><V><A><F><G><A><S><C><A><L><A><E><L><T><G><V><L><P><E><A><A><D><Y><R><A><A...
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).<BOP>
B5FPE5
Q7TNF0
DOC2A_MOUSE
Double C2-like domain-containing protein alpha
Mus
<M><R><G><R><R><G><D><R><M><T><I><N><I><Q><E><H><M><A><I><N><V><C><P><G><P><I><R><P><I><R><Q><I><S><D><Y><F><P><R><R><G><P><G><P><E><G><G><G><G><G><G><G><T><G><C><G><E><A><P><A><H><L><A><P><L><A><L><A><P><P><A><A><L><L><G><A><T><T><P><D><D><G><A><E><V><D><S><Y><D><S><D><D><T><T><A><L><G><T><L><E><F><D><L><L><Y><D><Q><A...
Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials...
Q7TNF0
O67035
RFRNP_AQUAE
Protein-only RNase P
Aquifex
<M><D><V><F><V><L><D><T><S><V><F><T><N><P><E><I><Y><R><T><F><E><E><D><Q><R><G><A><M><E><T><F><I><H><L><A><L><N><S><R><A><E><F><Y><M><P><T><S><V><Y><T><E><M><R><K><I><M><D><V><G><E><L><W><A><E><F><E><M><V><V><K><I><R><S><P><R><R><F><Q><L><T><V><P><A><D><F><L><Y><E><F><I><E><E><L><R><Y><R><I><N><K><G><L><R><I><A><E><E><H...
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.<BOP>
O67035
Q48CH3
METK_PSE14
Methionine adenosyltransferase
Pseudomonas
<M><S><E><Y><S><L><F><T><S><E><S><V><S><E><G><H><P><D><K><I><A><D><Q><I><S><D><A><V><L><D><A><I><I><A><E><D><K><Y><A><R><V><A><C><E><T><L><V><K><T><G><V><A><I><I><A><G><E><V><S><T><S><A><W><V><D><L><E><D><I><V><R><N><V><I><L><D><I><G><Y><N><S><S><D><V><G><F><D><G><A><T><C><G><V><M><N><I><I><G><K><Q><S><V><D><I><A><Q><G...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
Q48CH3
A0RQD7
GUAA_CAMFF
Glutamine amidotransferase
Campylobacter
<M><K><N><A><D><I><L><V><L><D><F><G><S><Q><Y><T><Q><L><I><A><R><R><L><R><E><Q><G><V><Y><A><E><L><M><P><F><N><V><S><I><E><A><I><K><A><K><N><P><K><G><I><I><L><S><G><G><P><A><S><V><Y><A><K><D><A><Y><F><C><D><E><G><V><F><T><L><G><L><P><V><L><G><I><C><Y><G><M><Q><L><L><A><H><K><N><G><A><D><V><A><P><A><G><H><K><E><Y><G><K><A...
Catalyzes the synthesis of GMP from XMP.<BOP>
A0RQD7
Q7UWI5
SECA2_RHOBA
Protein translocase subunit SecA 2
Rhodopirellula
<M><R><R><S><S><D><P><S><A><N><K><K><K><W><T><K><A><S><N><W><R><P><R><M><V><R><W><Q><R><Q><L><A><R><V><N><A><L><E><S><T><L><Q><A><E><D><D><Q><T><I><R><K><R><S><L><A><L><R><Y><R><A><M><A><G><E><K><L><S><E><L><L><P><E><A><Y><A><L><C><R><E><A><G><R><R><S><L><S><M><R><H><Y><D><V><Q><I><L><G><G><I><A><L><F><E><G><H><I><T><E...
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains acro...
Q7UWI5
A2SGN6
YCIB_METPP
Inner membrane-spanning protein YciB
Methylibium
<M><K><F><L><F><D><L><L><P><I><V><L><F><F><V><A><F><K><V><A><E><G><Q><P><D><A><A><A><A><F><A><S><Q><H><F><G><F><L><V><S><G><G><M><V><G><P><K><E><A><P><V><L><L><A><T><L><V><V><I><V><A><T><F><A><Q><I><G><W><L><L><L><R><G><R><K><V><D><T><M><L><W><V><S><L><G><L><V><T><V><L><G><G><A><T><V><W><F><H><N><E><T><F><I><K><W><K><P...
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP>
A2SGN6
P18700
TBB_STRPU
Beta-tubulin
Strongylocentrotus
<R><E><E><Y><P><D><R><I><M><N><T><F><S><V><V><P><S><P><K><V><S><D><T><V><V><E><P><Y><N><A><T><L><S><V><H><Q><L><V><E><N><T><D><E><T><Y><C><I><D><N><E><A><L><Y><D><I><C><F><R><T><L><K><L><T><T><P><T><Y><G><D><L><N><H><L><V><S><A><T><M><S><G><V><T><T><C><L><R><F><P><G><Q><L><N><A><D><L><R><K><L><A><V><N><M><V><P><F><P><R...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
P18700
B0JXU3
TRPA_MICAN
Tryptophan synthase alpha chain
Microcystis
<M><T><A><V><T><E><C><F><R><S><L><R><S><Q><G><N><C><A><L><I><P><F><I><T><A><G><D><P><D><L><S><T><T><A><Q><A><L><R><I><L><D><R><A><G><A><D><L><I><E><L><G><V><P><Y><S><D><P><L><A><D><G><P><V><I><Q><S><A><A><T><R><A><L><N><R><G><V><K><L><E><D><V><L><E><I><V><K><N><A><Q><G><E><V><K><A><P><I><I><L><F><T><Y><Y><N><P><I><Y><H...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
B0JXU3
P19114
IL2_SHEEP
T-cell growth factor
Ovis
<M><Y><K><I><Q><L><L><S><C><I><A><L><T><L><A><L><V><A><N><G><A><P><T><S><S><S><T><G><N><T><M><K><E><V><K><S><L><L><L><D><L><Q><L><L><L><E><K><V><K><N><P><E><N><L><K><L><S><R><M><H><T><F><N><F><Y><M><P><K><V><N><A><T><E><L><K><H><L><K><C><L><L><E><E><L><K><L><L><E><E><V><L><D><L><A><P><S><K><N><L><N><T><R><E><I><K><D><S...
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG...
P19114
Q7V938
CRCB1_PROMM
Putative fluoride ion transporter CrcB 1
Prochlorococcus
<M><S><D><L><A><L><P><A><W><Q><A><S><L><V><A><I><G><A><V><P><G><A><W><L><R><L><R><V><V><N><H><L><E><P><M><V><P><R><K><H><W><G><T><F><A><V><N><M><V><A><A><F><A><L><G><L><V><L><A><L><Q><A><K><C><A><P><E><S><G><A><S><P><L><I><L><L><I><G><V><G><F><F><G><S><L><S><T><F><S><T><F><A><V><E><V><L><N><T><L><R><E><H><R><W><S><E><A...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
Q7V938
P01089
2SS_RICCO
RL2
Ricinus
<M><A><K><L><I><P><T><I><A><L><V><S><V><L><L><F><I><I><A><N><A><S><F><A><Y><R><T><T><I><T><T><I><E><I><D><E><S><K><G><E><R><E><G><S><S><S><Q><Q><C><R><Q><E><V><Q><R><K><D><L><S><S><C><E><R><Y><L><R><Q><S><S><S><R><R><S><P><G><E><E><V><L><R><M><P><G><D><E><N><Q><Q><Q><E><S><Q><Q><L><Q><Q><C><C><N><Q><V><K><Q><V><R><D><E...
2S seed storage proteins.<BOP>
P01089
A5VHT8
PURL_LIMRD
Phosphoribosylformylglycinamidine synthase subunit II
Limosilactobacillus
<M><K><Q><A><M><T><P><E><E><I><K><E><K><K><P><Y><L><D><W><S><L><T><E><A><E><Y><D><Y><I><R><T><Q><L><L><G><R><L><P><N><Y><T><E><T><G><L><F><S><A><M><W><S><E><H><C><S><Y><K><K><S><K><P><V><L><R><L><F><P><N><K><N><E><R><V><L><Q><G><P><G><E><G><A><G><V><V><D><I><D><D><G><Q><A><V><V><F><K><A><E><S><H><N><H><P><T><T><V><E><P...
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three su...
A5VHT8
P94419
YCLO_BACSU
Petrobactin import system permease protein YclO
Bacillus
<M><R><N><Q><M><K><I><A><L><L><V><G><L><A><I><V><C><I><G><L><F><L><F><Y><D><L><G><N><W><D><Y><T><L><P><R><R><I><K><K><V><A><A><I><V><L><T><G><G><A><I><A><F><S><T><M><I><F><Q><T><I><T><N><N><R><I><L><T><P><S><I><L><G><L><D><S><L><Y><M><L><I><Q><T><G><I><I><F><L><F><G><S><A><N><M><V><I><M><N><K><N><I><N><F><I><I><S><V><L...
Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4-catecholate siderophore produced by many members of the B.cereus group, including B.anthracis. Probably responsible for the translocation of the substrate across the membrane.<BOP>
P94419
Q8TRB8
RPO1C_METAC
DNA-directed RNA polymerase subunit A''
Methanosarcina
<M><S><E><A><T><I><D><S><M><L><K><D><L><P><F><P><S><N><I><L><N><T><L><R><E><D><V><L><K><A><G><V><S><K><K><E><M><E><E><I><I><E><K><M><M><E><E><Y><A><T><S><C><I><E><P><C><D><A><A><G><V><V><A><A><Q><S><I><G><E><P><G><T><Q><M><T><M><R><T><F><H><Y><A><G><V><A><E><I><N><V><T><L><G><L><P><R><L><I><E><I><V><D><A><R><K><I><P><S...
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.<BOP>
Q8TRB8
Q9G2U7
CYB_PROGY
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Proechimys
<M><T><N><L><R><K><S><H><P><L><I><K><I><I><N><H><S><F><I><D><L><P><T><P><S><N><I><S><T><W><W><N><F><G><S><L><L><G><V><C><L><I><L><Q><I><I><T><G><L><F><L><A><M><H><Y><T><A><D><T><T><T><A><F><S><S><V><T><H><I><C><R><D><V><N><Y><G><W><L><I><R><H><A><H><A><N><G><A><S><M><F><F><I><F><L><Y><F><H><I><G><R><G><I><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q9G2U7
Q164E3
ENO_ROSDO
2-phosphoglycerate dehydratase
Roseobacter
<M><S><T><I><I><D><I><H><A><R><E><I><L><D><S><R><G><N><P><T><V><E><V><D><V><I><L><E><D><G><T><M><G><R><A><A><V><P><S><G><A><S><T><G><A><Y><E><A><V><E><R><R><D><G><D><K><T><R><Y><M><G><K><G><V><L><E><A><C><A><A><V><N><G><E><I><A><D><A><L><V><G><L><D><A><T><E><Q><V><D><I><D><A><S><M><I><E><L><D><G><T><A><N><K><S><R><L><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
Q164E3
A8LC46
RL14_FRASN
50S ribosomal protein L14
unclassified Frankia
<M><I><Q><Q><E><S><R><L><R><V><A><D><N><T><G><A><R><E><I><L><C><I><R><V><L><G><G><S><G><R><R><Y><A><G><I><G><D><I><I><V><G><T><V><K><D><A><L><P><G><A><G><V><K><R><G><D><V><V><K><A><V><V><V><R><T><K><K><E><R><R><R><P><D><G><S><Y><I><R><F><D><E><N><A><A><V><L><I><R><D><G><G><D><P><R><G><T><R><I><F><G><P><V><G><R><E><L><R...
Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP>
A8LC46
Q9P7V9
UBP9_SCHPO
Ubiquitin-specific-processing protease 9
Schizosaccharomyces
<M><S><L><L><R><W><M><G><M><N><S><P><G><S><T><D><R><R><K><S><T><W><E><A><E><L><P><K><P><S><I><R><P><E><T><L><T><D><R><F><Y><G><L><T><N><Y><G><N><T><C><Y><V><S><S><V><L><V><S><L><Y><H><L><K><P><F><R><D><S><L><N><S><Y><P><L><P><S><A><P><P><N><F><K><S><V><C><T><K><T><N><H><P><E><S><S><S><S><R><H><S><K><K><K><S><M><E><N><R...
Ubiquitin C-terminal hydrolase involved in regulating actin dynamics and/or endocytosis at cell tips and septa.<BOP>
Q9P7V9
B3EFB1
IF2_CHLL2
Translation initiation factor IF-2
Chlorobium
<M><A><I><E><E><M><E><K><K><Y><R><I><S><D><I><A><R><E><L><Q><V><S><P><Q><E><V><L><Q><F><V><K><L><E><G><G><K><V><A><S><T><S><S><M><V><D><Q><G><M><R><E><L><I><F><G><H><F><S><N><E><K><K><M><V><D><E><T><M><K><I><R><Q><E><K><Q><R><R><L><S><R><L><E><E><Q><S><R><K><T><Y><E><K><E><R><Q><L><K><E><T><L><H><S><A><S><V><A><P><A><V...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
B3EFB1
B3GYI3
SYV_ACTP7
Valyl-tRNA synthetase
Actinobacillus
<M><T><Q><N><L><Q><M><A><D><R><F><D><S><S><A><V><E><Q><A><L><Y><K><H><W><E><E><Q><G><Y><F><K><P><T><E><N><P><S><L><P><S><Y><C><I><A><I><P><P><P><N><V><T><G><S><L><H><M><G><H><A><F><Q><Q><T><L><M><D><T><L><I><R><F><N><R><M><E><G><N><N><T><L><W><Q><T><G><T><D><H><A><G><I><A><T><Q><M><V><V><E><R><K><I><A><A><E><E><G><K><T...
Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.<BOP>
B3GYI3
Q8DNI9
SCPB_STRR6
Segregation and condensation protein B
Streptococcus
<M><S><T><L><A><K><I><E><A><L><L><F><V><A><G><E><D><G><I><R><V><R><Q><L><A><E><L><L><S><L><P><P><T><G><I><Q><Q><S><L><G><K><L><A><Q><K><Y><E><K><D><P><D><S><S><L><A><L><I><E><T><S><G><A><Y><R><L><V><T><K><P><Q><F><A><E><I><L><K><E><Y><S><K><A><P><I><N><Q><S><L><S><R><A><A><L><E><T><L><S><I><I><A><Y><K><Q><P><I><T><R><I...
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.<BOP>
Q8DNI9
P94892
RPOC_LEUMM
Transcriptase subunit beta'
Leuconostoc
<M><A><I><D><V><N><K><F><E><S><M><Q><I><A><L><A><S><P><D><K><I><R><S><W><S><Y><G><E><V><K><K><P><E><T><I><N><Y><R><T><L><K><P><E><K><D><G><L><F><D><E><R><I><F><G><P><T><K><D><Y><E><C><A><C><G><K><Y><K><R><I><R><Y><K><G><I><V><C><D><R><C><G><V><E><V><T><S><S><K><V><R><R><E><R><M><G><H><I><E><L><A><A><P><V><T><H><I><W><Y...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
P94892
Q08AG5
ZN844_HUMAN
Zinc finger protein 844
Homo
<M><D><L><V><A><F><E><D><V><A><V><N><F><T><Q><E><E><W><S><L><L><D><P><S><Q><K><N><L><Y><R><E><V><M><Q><E><T><L><R><N><L><A><S><I><G><E><K><W><K><D><Q><N><I><E><D><Q><Y><K><N><P><R><N><N><L><R><S><L><L><G><E><R><V><D><E><N><T><E><E><N><H><C><G><E><T><S><S><Q><I><P><D><D><T><L><N><K><K><T><S><P><G><V><K><S><C><E><S><S><V...
May be involved in transcriptional regulation.<BOP>
Q08AG5
B2FMC1
SST_STRMK
Serine O-succinyltransferase
Stenotrophomonas maltophilia group
<M><T><E><F><I><P><P><G><T><R><F><H><A><L><P><S><P><F><P><F><K><R><G><G><A><L><H><G><A><R><V><A><Y><E><T><W><G><T><L><A><A><D><A><S><N><A><I><L><I><V><T><G><L><S><P><D><A><H><A><A><A><N><D><A><N><P><A><A><G><W><W><E><G><M><V><G><P><G><K><A><I><D><T><D><R><W><F><V><V><C><V><N><S><L><G><S><C><K><G><S><T><G><P><A><S><L><N...
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.<BOP>
B2FMC1
Q9USM6
CYB52_SCHPO
Probable cytochrome b5 2
Schizosaccharomyces
<M><A><E><K><T><I><T><V><E><E><V><L><K><H><N><T><R><D><D><L><Y><I><V><V><K><D><K><V><Y><D><I><S><K><F><L><D><A><H><P><G><G><E><E><V><L><V><D><L><A><G><R><D><A><S><G><P><F><E><D><V><G><H><S><E><D><A><Q><E><L><L><E><K><F><Y><I><G><N><L><L><R><T><E><D><G><P><Q><L><P><T><T><G><A><A><A><G><G><S><G><Y><D><S><S><Q><P><V><K><P...
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.<BOP>
Q9USM6
G1UB44
MELA_LACAC
Alpha-galactosidase Mel36A
Lactobacillus
<M><T><S><N><L><I><K><F><D><D><Q><N><K><V><F><H><L><H><N><K><Q><I><S><Y><L><L><S><I><E><D><G><G><T><L><S><H><L><Y><F><G><G><A><V><K><N><Y><N><N><Q><L><K><Y><P><R><L><D><R><G><F><S><G><N><L><P><E><S><L><D><R><T><F><S><R><D><S><L><P><K><E><Y><S><S><A><G><E><M><D><F><H><T><P><A><T><I><V><R><N><P><D><G><S><N><A><L><F><L><A...
Hydrolyzes the short-chain alpha-galactosaccharide raffinose.<BOP>
G1UB44
A4WPE3
RL25_CERS5
General stress protein CTC
Cereibacter
<M><A><G><E><I><P><D><F><Q><A><E><V><R><T><G><T><G><K><G><A><A><R><Q><A><R><R><E><G><Y><V><P><G><I><V><Y><G><G><G><Q><E><P><L><S><I><N><V><K><Y><N><D><L><L><N><R><L><K><K><G><R><F><L><Q><T><L><F><N><L><K><V><E><G><Q><E><D><V><R><V><I><C><R><G><V><Q><R><D><V><V><K><D><L><P><T><H><V><D><F><M><R><L><R><R><T><S><R><I><N><L...
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP>
A4WPE3
Q5M191
RECX_STRT1
Regulatory protein RecX
Streptococcus
<M><K><I><T><K><I><E><K><K><K><R><L><Y><L><V><E><I><D><K><K><E><S><L><Y><V><T><E><D><T><I><V><K><Y><M><L><T><K><E><M><A><L><S><K><D><Q><L><E><D><I><K><N><F><A><Q><F><S><H><G><K><N><L><A><L><Y><F><I><S><F><K><Q><R><T><E><K><E><V><R><D><Y><L><F><K><H><E><I><N><P><H><I><I><P><Q><I><I><D><N><L><K><K><D><H><W><I><D><D><Y><K...
Modulates RecA activity.<BOP>
Q5M191
C8V4J5
DBAA_EMENI
Derivative of benzaldehyde biosynthesis cluster protein A
Aspergillus subgen. Nidulantes
<M><S><Q><H><V><K><S><P><E><P><T><E><S><P><K><P><R><Q><K><P><G><A><A><C><E><E><C><R><R><R><K><L><R><C><D><R><R><Q><P><Q><C><R><L><C><E><A><S><G><V><E><C><Q><V><I><T><A><R><P><S><R><G><P><K><P><A><L><E><G><A><L><L><Q><Q><S><T><T><N><F><S><G><P><T><D><D><H><P><L><D><T><P><M><L><D><D><Q><I><D><L><S><G><W><Q><L><P><V><M><D...
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of the antibiotic 2,4- dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives . Probably binds the conserved motif 5'-CT/CCG/AGA/CG/CT/A/CA/TT/A/GC-3' found in all dba cluster promoters and that sho...
C8V4J5
P44489
UVRC_HAEIN
Excinuclease ABC subunit C
Haemophilus
<M><F><D><A><K><K><F><L><T><D><V><S><H><E><P><G><V><Y><R><M><Y><D><D><K><D><Q><V><I><Y><V><G><K><A><K><D><L><K><K><R><L><S><S><Y><F><R><K><N><L><S><S><K><K><T><E><A><L><V><A><S><I><H><H><I><D><T><T><L><T><S><S><E><T><E><A><L><L><L><E><H><N><F><I><K><L><Y><Q><P><R><Y><N><V><L><L><R><D><D><K><S><Y><P><F><I><L><L><T><K><E...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
P44489
P21450
EDNRA_BOVIN
Endothelin receptor type A
Bos
<M><E><T><F><W><L><R><L><S><F><W><V><A><L><V><G><G><V><I><S><D><N><P><E><S><Y><S><T><N><L><S><I><H><V><D><S><V><A><T><F><H><G><T><E><L><S><F><V><V><T><T><H><Q><P><T><N><L><A><L><P><S><N><G><S><M><H><N><Y><C><P><Q><Q><T><K><I><T><S><A><F><K><Y><I><N><T><V><I><S><C><T><I><F><I><V><G><M><V><G><N><A><T><L><L><R><I><I><Y><Q...
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.<BOP>
P21450
Q5UCA8
BRYP_PHYPA
Physcomitrin
Physcomitrium
<M><A><E><A><I><I><P><A><A><E><L><S><I><K><T><L><Q><N><I><V><E><G><I><T><G><V><D><R><K><I><A><I><G><F><K><N><L><T><D><Y><T><L><E><N><L><G><V><Y><F><N><S><G><S><S><D><R><S><I><A><Y><K><I><N><A><Q><E><A><L><L><F><S><A><R><K><S><D><H><T><A><R><G><T><V><G><T><F><S><Y><Y><I><Q><D><E><D><K><T><V><H><V><M><W><S><V><P><F><D><Y...
Actinoporin-related protein having hemolytic activity in vitro. Binds probably a phosphocholine derivative with the unique amido or hydroxyl groups found in sphingomyelin. Involved in drought tolerance.<BOP>
Q5UCA8
A0AIS3
DNAJ_LISW6
Chaperone protein DnaJ
Listeria
<M><A><K><R><D><Y><Y><E><V><L><G><I><S><K><S><A><S><A><D><E><I><K><K><A><Y><R><K><L><S><K><Q><Y><H><P><D><I><N><K><E><A><G><A><D><E><K><F><K><E><I><S><E><A><Y><E><V><L><S><D><S><Q><K><R><A><Q><Y><D><Q><Y><G><H><V><D><P><N><Q><G><F><G><G><G><A><G><G><G><F><S><G><G><G><F><S><G><F><E><D><I><F><D><T><F><F><G><G><G><G><R><Q...
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou...
A0AIS3
Q7VR21
ACP_BLOFL
Acyl carrier protein
Candidatus Blochmannia
<M><S><I><V><E><E><K><V><K><T><I><I><A><E><Q><L><G><V><K><Q><E><E><V><V><N><H><A><S><F><V><D><D><L><G><A><D><S><L><D><T><V><E><L><V><M><A><L><E><E><E><F><D><I><E><I><P><D><E><E><A><E><K><I><T><T><V><Q><A><A><I><D><F><I><H><T><N><Q><K>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
Q7VR21
Q9KF39
PCRB_HALH5
Glycerol-1-phosphate heptaprenyltransferase
Halalkalibacterium (ex Joshi et al. 2022)
<M><M><L><E><F><Q><E><W><R><H><V><F><K><L><D><P><N><K><E><L><N><D><D><D><L><E><A><I><C><E><S><G><T><D><G><I><L><V><G><G><S><D><G><V><T><L><D><N><T><L><Q><L><L><A><R><I><R><R><F><S><V><S><C><A><L><E><V><S><N><L><E><S><I><T><P><G><F><D><H><Y><F><I><P><S><V><V><N><S><G><E><V><K><W><I><S><G><L><H><H><E><A><V><K><E><F><G><P...
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1...
Q9KF39
P0CH41
CEII9_CENEL
Cell9
Centruroides
<K><E><G><Y><L><V><N><H><S><T><G><C><K><Y><E><C><F><K><L><G><D><N><D><Y><C><L><R><E><C><R><Q><G><Y><G><K><G><A><G><G><Y><C><Y><A><F><G><C><W><C><T><H><L><Y><E><Q><A><V><V><W><P><L><P><K><K><T><C><N><A>
Beta toxins bind at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active against mammals and lethal to mice. Selectively modulates Nav1.4/SCN4A, a sodium channel pre...
P0CH41
A1WAS7
LEUC_ACISJ
Isopropylmalate isomerase
unclassified Acidovorax
<M><G><R><T><L><Y><D><K><I><F><D><E><H><V><V><H><T><E><E><D><G><T><A><V><L><Y><I><D><R><H><L><V><H><E><V><T><S><P><Q><A><F><E><G><L><R><E><A><G><R><K><V><W><R><V><S><S><I><V><A><T><A><D><H><N><T><P><T><T><G><W><E><R><G><Y><D><G><I><A><D><P><I><S><K><E><Q><I><V><T><L><D><K><N><I><Q><E><S><G><A><A><A><F><F><P><F><L><S><K...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
A1WAS7
Q4JBL6
CBID_SULAC
Cobalt-precorrin-6A synthase
Sulfolobus
<M><R><G><N><T><A><L><M><S><T><L><K><R><F><G><I><T><T><G><A><T><A><A><A><A><S><K><A><S><V><I><F><L><I><K><N><E><T><P><K><T><V><T><I><P><T><P><I><G><L><R><L><E><I><S><V><G><N><Y><S><R><K><E><S><E><F><C><A><S><A><K><K><F><S><G><D><N><P><D><I><L><D><G><L><E><I><I><A><C><S><G><R><S><N><S><Q><T><I><T><I><T><A><E><E><G><V><G...
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.<BOP>
Q4JBL6
B0B9U7
TSAD_CHLT2
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Chlamydia
<M><L><T><L><G><L><E><S><S><C><D><E><T><S><C><S><L><V><Q><N><G><K><I><L><A><N><K><I><A><S><Q><D><I><H><A><S><Y><G><G><V><I><P><E><L><A><S><R><A><H><L><Q><T><F><P><E><L><L><T><A><A><T><Q><S><A><G><V><S><L><E><D><I><E><L><I><S><V><A><N><T><P><G><L><I><G><A><L><S><I><G><V><N><F><A><K><G><L><A><S><G><L><K><R><P><L><I><G><V...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
B0B9U7
Q21EN9
DSBB_SACD2
Disulfide oxidoreductase
Saccharophagus
<M><K><I><T><K><L><P><S><Y><R><Q><T><A><L><I><I><F><A><G><C><V><G><L><I><L><A><A><L><Y><M><Q><E><V><L><G><L><H><P><C><P><L><C><I><T><Q><R><I><F><I><I><G><V><G><L><I><S><L><I><A><A><I><H><N><P><A><A><L><G><R><K><V><Y><G><C><L><A><T><L><S><G><V><I><G><A><G><V><S><A><R><H><V><W><L><Q><N><L><P><E><D><Q><V><P><A><C><G><P><D...
Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.<BOP>
Q21EN9
Q492P7
PGSA_BLOPB
Phosphatidylglycerophosphate synthase
Candidatus Blochmannia
<M><D><I><I><N><I><P><T><Y><L><T><L><L><R><V><V><M><V><P><F><F><T><V><M><F><Y><L><P><V><R><W><A><P><M><I><C><T><I><M><F><F><V><A><A><V><T><D><W><F><D><G><F><L><A><R><R><W><K><Q><T><T><S><F><G><K><F><L><D><P><V><A><D><K><V><M><I><V><A><A><L><V><L><I><A><E><H><F><H><T><W><W><V><T><L><P><A><S><I><I><I><I><R><E><V><I><I><L...
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.<BOP>
Q492P7
P17928
CALM_MEDSA
Calmodulin
Medicago
<M><A><D><Q><L><T><D><E><Q><I><S><E><F><K><E><A><F><S><L><F><D><K><D><G><D><G><C><I><T><T><K><E><L><G><T><V><M><R><S><L><G><Q><N><P><T><E><A><E><L><Q><D><M><I><N><E><V><D><A><D><G><N><G><T><I><D><F><P><E><F><L><N><L><M><A><R><K><M><K><D><T><D><S><E><E><E><L><K><E><A><F><R><V><F><D><K><D><Q><N><G><F><I><S><A><A><E><L><R...
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.<BOP>
P17928
Q9JJ74
RAMP1_RAT
Receptor activity-modifying protein 1
Rattus
<M><A><P><G><L><R><G><L><P><R><R><G><L><W><L><L><L><A><H><H><L><F><M><V><T><A><C><R><D><P><D><Y><G><T><L><I><Q><E><L><C><L><S><R><F><K><E><D><M><E><T><I><G><K><T><L><W><C><D><W><G><K><T><I><G><S><Y><G><E><L><T><H><C><T><K><L><V><A><N><K><I><G><C><F><W><P><N><P><E><V><D><K><F><F><I><A><V><H><H><R><Y><F><S><K><C><P><V><S...
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.<BOP>
Q9JJ74
O75342
LX12B_HUMAN
Epidermis-type lipoxygenase 12
Homo
<M><A><T><Y><K><V><R><V><A><T><G><T><D><L><L><S><G><T><R><D><S><I><S><L><T><I><V><G><T><Q><G><E><S><H><K><Q><L><L><N><H><F><G><R><D><F><A><T><G><A><V><G><Q><Y><T><V><Q><C><P><Q><D><L><G><E><L><I><I><I><R><L><H><K><E><R><Y><A><F><F><P><K><D><P><W><Y><C><N><Y><V><Q><I><C><A><P><N><G><R><I><Y><H><F><P><A><Y><Q><W><M><D><G...
Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy species . In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-...
O75342
Q7T3I7
RBM38_XENLA
RNA-binding protein XSeb4R
Xenopus
<M><H><T><V><Q><K><D><T><T><F><T><K><I><F><V><G><G><L><P><Y><H><T><T><D><A><S><L><R><K><Y><F><E><V><F><G><D><I><D><E><A><V><V><I><T><D><R><Q><T><A><K><S><R><G><Y><G><F><V><T><M><S><D><R><A><A><A><E><R><A><C><K><D><P><N><P><I><I><D><G><R><K><A><N><V><N><L><A><Y><L><G><A><K><P><R><N><L><Q><S><A><F><T><I><G><V><Q><Q><L><H...
RNA-binding protein that specifically bind the 3'-UTR of VegT transcripts, leading to maintain their stability and stimulate their translation, thereby playing a role in germ layer formation. VegT is a localized maternal determinant essentially required for endoderm formation. Also has some proneural function in the op...
Q7T3I7
Q9HC77
CENPJ_HUMAN
LYST-interacting protein 1
Homo
<M><F><L><M><P><T><S><S><E><L><N><S><G><Q><N><F><L><T><Q><W><M><T><N><P><S><R><A><G><V><I><L><N><R><G><F><P><I><L><E><A><D><K><E><K><R><A><A><V><D><I><S><T><S><F><P><I><K><G><T><H><F><S><D><S><F><S><F><I><N><E><E><D><S><L><L><E><E><Q><K><L><E><S><N><N><P><Y><K><P><Q><S><D><K><S><E><T><H><T><A><F><P><C><I><K><K><G><P><Q...
Plays an important role in cell division and centrosome function by participating in centriole duplication . Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar micr...
Q9HC77
A3LZZ1
HSB1_PICST
Histone H2B.1
Scheffersomyces
<M><A><P><P><K><A><E><K><K><P><A><S><K><A><P><A><E><K><K><P><A><A><K><K><T><A><S><A><T><D><S><K><K><R><T><K><T><R><K><E><T><Y><S><S><Y><I><Y><K><V><L><K><Q><T><H><P><D><T><G><I><S><Q><K><A><M><S><I><M><N><S><F><V><N><D><I><F><E><R><I><A><S><E><A><S><K><L><A><A><Y><N><K><K><S><T><I><S><A><R><E><I><Q><T><A><V><R><L><I><L...
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v...
A3LZZ1
P0CC10
LRC4B_RAT
Netrin-G3 ligand
Rattus
<M><A><Q><A><H><I><Q><G><S><P><C><P><L><L><P><P><G><R><M><S><W><P><Q><G><A><L><L><L><L><W><L><F><S><P><P><L><R><A><G><G><G><G><V><A><V><T><S><A><A><G><G><G><S><P><P><A><T><S><C><P><A><A><C><S><C><S><N><Q><A><S><R><V><I><C><T><R><R><E><L><A><E><V><P><A><S><I><P><V><N><T><R><Y><L><N><L><Q><E><N><S><I><Q><V><I><R><T><D><T...
Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner.<BOP>
P0CC10
Q58167
TMPS_METJA
Thymidylate synthase
Methanocaldococcus
<M><V><L><N><I><N><S><F><Y><K><N><C><R><G><E><F><M><R><A><V><F><I><Y><H><K><N><N><Q><R><M><E><K><F><Y><K><N><L><L><N><E><P><D><F><C><R><I><C><D><D><C><Y><N><C><R><G><N><W><T><F><K><N><N><V><K><N><I><V><I><E><E><V><Y><E><E><F><V><D><N><P><Y><D><Y><L><P><E><L><P><E><G><D><I><C><I><A><Q><L><H><E><D><L><L><Y><E><L><P><L><L...
Is able to catalyze the biosynthesis of dTMP using dUMP, tetrahydrofolate and formaldehyde in vitro, i.e. a reaction equivalent to that catalyzed by bacterial thymidylate synthases (EC 2.1.1.45). However, M.jannaschii like most methanogenic Archaea lacks folates, thus the physiological cosubstrate is unknown but is lik...
Q58167
B2V709
SYA_SULSY
Alanyl-tRNA synthetase
unclassified Sulfurihydrogenibium
<M><K><Y><M><T><A><D><E><I><R><Q><S><F><L><K><Y><F><E><S><K><G><H><T><I><V><K><S><A><S><I><I><P><E><N><D><P><T><L><L><F><V><N><A><G><M><V><P><F><K><N><V><F><L><G><L><E><E><R><P><Y><K><R><A><A><S><C><Q><K><V><F><R><V><S><G><K><H><N><D><L><E><N><V><G><Y><T><P><R><H><H><T><F><F><E><M><L><G><N><F><S><F><G><D><Y><F><K><K><E...
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP>
B2V709
A1A0A2
IF2_BIFAA
Translation initiation factor IF-2
Bifidobacterium
<M><P><K><A><R><V><Y><E><L><A><K><E><L><G><V><D><S><K><T><V><L><S><K><L><E><A><M><G><E><F><V><K><S><A><S><S><T><V><E><P><P><V><A><R><K><L><R><N><A><F><A><S><S><G><Q><G><N><A><S><D><S><K><K><P><G><H><T><A><K><K><P><A><E><P><A><S><H><S><M><P><K><P><A><A><P><S><A><P><K><P><A><A><P><A><A><P><K><P><R><H><A><A><S><K><S><D><A...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
A1A0A2
Q84BZ2
ANDAD_BURCE
Anthranilate 1,2-dioxygenase small subunit
Burkholderia cepacia complex
<M><E><N><L><T><E><D><M><K><T><W><F><E><I><Y><M><L><Q><N><R><Y><I><G><H><L><D><N><D><R><L><E><R><W><P><E><M><F><T><E><D><C><T><Y><E><I><V><P><K><E><N><A><D><L><G><L><P><V><G><I><V><H><C><T><N><Q><R><M><L><R><D><R><V><V><S><L><R><H><A><N><I><Y><E><E><H><T><Y><R><H><M><T><S><G><L><A><I><V><A><Q><R><D><G><E><I><D><T><E><S...
Oxygenase component of anthranilate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into anthranilate to form catechol. Can also act on benzoate and salicylate but not on 2-chlorobenzoate or o-toluate.<BOP>
Q84BZ2
Q0AUH2
RPOB_SYNWW
Transcriptase subunit beta
Syntrophomonas
<M><A><H><L><E><Q><F><G><R><V><S><R><L><S><Y><S><R><I><K><E><P><V><E><L><P><N><L><I><Q><I><Q><K><N><S><Y><D><W><F><L><E><H><G><L><R><E><A><L><Q><E><V><F><P><I><S><D><F><T><G><N><L><E><L><G><F><L><D><Y><S><M><G><E><P><K><Y><S><I><N><E><C><K><E><R><D><V><S><Y><Q><A><P><L><K><L><K><V><R><L><T><D><K><E><N><G><E><I><K><E><S...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q0AUH2
Q5REL7
TCO2_PONAB
Transcobalamin II
Pongo
<M><R><H><L><G><A><L><L><F><L><L><G><V><L><G><A><L><A><E><I><C><E><I><P><E><V><D><S><H><L><V><E><K><L><G><Q><H><L><L><P><W><M><D><R><L><S><L><E><H><L><N><P><S><I><Y><V><D><L><R><L><S><S><L><Q><A><G><T><K><E><E><L><Y><L><H><S><L><K><L><G><Y><Q><Q><C><L><L><G><S><A><F><S><E><D><D><G><D><C><Q><G><K><P><S><M><G><Q><L><A><L...
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.<BOP>
Q5REL7
B6JGF9
ACPS_AFIC5
4'-phosphopantetheinyl transferase AcpS
Afipia
<M><I><L><G><I><G><S><D><T><I><D><I><R><R><V><Q><E><V><I><E><R><H><G><A><R><F><I><D><R><I><F><T><E><A><E><Q><A><K><A><E><R><R><A><K><A><P><R><A><W><V><A><T><Y><A><K><R><F><A><A><K><E><A><C><A><K><A><L><G><T><G><I><R><Q><G><V><W><W><R><D><M><G><V><V><N><L><P><G><G><R><P><T><M><Q><L><T><G><G><A><L><V><R><L><E><S><L><L><P...
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP>
B6JGF9
P02477
CRYAA_PHOPH
Alpha-crystallin A chain
Phocoena
<M><D><I><A><I><Q><H><P><W><F><K><R><A><L><G><P><F><Y><P><S><R><L><F><D><Q><F><F><G><E><G><L><F><E><Y><D><L><L><P><F><L><S><S><T><I><S><P><Y><Y><R><Q><S><L><F><R><S><V><L><D><S><G><I><S><E><V><R><S><D><R><D><K><F><V><I><F><L><D><V><K><H><F><S><P><E><D><L><T><V><K><V><Q><E><D><F><V><E><I><H><G><K><H><N><E><R><Q><D><D><H...
Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.<BOP>
P02477
A1WW18
GLGA_HALHL
Starch [bacterial glycogen] synthase
Halorhodospira
<M><R><V><L><F><A><T><A><E><A><W><P><L><A><K><T><G><G><L><G><D><V><A><F><G><L><T><R><A><L><A><E><L><D><C><D><V><R><L><L><M><P><A><Y><P><G><T><V><E><Q><L><E><G><E><V><R><R><H><T><A><E><L><A><G><E><G><V><T><L><I><E><G><R><L><P><G><T><G><V><G><V><W><L><L><D><D><P><P><L><F><A><R><V><G><G><P><Y><A><T><A><G><G><D><A><W><P><D...
Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP>
A1WW18
P40492
FYV10_YEAST
Probable E3 ubiquitin-protein ligase GID9
Saccharomyces
<M><A><E><K><S><I><F><N><E><P><D><V><D><F><H><L><K><L><N><Q><Q><L><F><H><I><P><Y><E><L><L><S><K><R><I><K><H><T><Q><A><V><I><N><K><E><T><K><S><L><H><E><H><T><A><A><L><N><Q><I><F><E><H><N><D><V><E><H><D><E><L><A><L><A><K><I><T><E><M><I><R><K><V><D><H><I><E><R><F><L><N><T><Q><I><K><S><Y><C><Q><I><L><N><R><I><K><K><R><L><E...
Required for the adaptation to the presence of glucose in the growth medium; mediates the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium . Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1) . May catalyze ubiquitination ...
P40492
P61789
TX5A_HETVE
Toxin AU5A
Heteropoda
<D><D><D><C><G><W><I><M><D><D><C><T><S><D><S><D><C><C><P><N><W><V><C><S><K><T><G><F><V><K><N><I><C><K><Y><E><M>
Blocks calcium channels (Cav).<BOP>
P61789
A7GK37
RS5_BACCN
30S ribosomal protein S5
Bacillus cereus group
<M><R><R><I><D><P><S><K><L><E><L><E><E><R><V><V><T><I><N><R><V><A><K><V><V><K><G><G><R><R><F><R><F><A><A><L><V><V><V><G><D><K><N><G><H><V><G><F><G><T><G><K><A><Q><E><V><P><D><A><I><R><K><A><I><E><D><A><K><K><N><L><I><E><V><P><L><V><G><T><S><I><P><H><E><I><I><G><H><F><G><A><G><E><V><F><L><K><P><A><A><E><G><T><G><V><I><A...
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP>
A7GK37
O62820
MOTI_BOVIN
Motilin-associated peptide
Bos
<M><L><S><R><K><A><T><A><V><L><L><A><V><H><A><A><A><M><L><A><S><Q><T><E><A><F><V><P><I><F><T><Y><G><E><V><R><R><M><Q><E><K><E><R><Y><K><G><Q><K><K><S><L><S><V><Q><Q><R><S><E><E><V><G><P><V><D><P><T><E><P><W><E><E><K><Q><E><V><I><K><L><T><A><P><V><E><I><G><M><R><M><N><S><R><Q><L><E><K><Y><Q><A><T><L><E><G><L><L><R><E><V...
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.<BOP>
O62820
Q2RJH7
COBQ_MOOTA
Cobyric acid synthase
Moorella
<M><A><K><A><I><M><L><Q><G><T><S><S><N><V><G><K><S><V><L><A><A><A><L><C><R><I><F><H><R><N><G><Y><R><V><S><P><F><K><S><Q><N><M><A><L><N><S><G><A><T><P><D><G><G><E><M><G><R><A><Q><I><V><Q><A><M><A><A><G><V><V><P><R><V><E><M><N><P><I><L><L><K><P><T><A><H><A><S><S><Q><V><I><V><L><G><R><P><V><G><N><L><G><A><R><E><Y><H><G><H...
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.<BOP>
Q2RJH7
Q9JXB3
RF2_NEIMB
Peptide chain release factor 2
Neisseria
<M><E><A><E><V><I><N><Q><L><N><N><T><L><N><D><L><E><K><R><S><E><D><I><R><V><Y><M><D><Y><Q><G><K><K><D><R><L><E><E><V><I><G><L><S><E><D><P><E><L><W><N><D><P><K><R><A><Q><E><I><G><K><E><R><K><I><L><E><G><I><V><L><T><L><D><N><I><A><S><G><I><E><D><N><R><M><L><I><E><M><T><V><E><E><N><D><E><E><G><F><A><A><V><Q><E><D><V><A><G...
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.<BOP>
Q9JXB3
P48652
NU1M_HORSE
NADH dehydrogenase subunit 1
Equus
<M><F><M><I><N><V><L><L><L><I><V><P><I><L><L><A><V><A><F><L><T><L><V><E><R><K><V><L><G><Y><M><Q><L><R><K><G><P><N><I><V><G><P><Y><G><L><L><Q><P><I><A><D><A><L><K><L><F><I><K><E><P><L><Q><P><L><T><S><S><T><S><M><F><I><I><A><P><I><L><A><L><T><L><A><L><T><M><W><I><P><L><P><M><P><Y><P><L><I><N><M><N><L><G><I><L><F><M><L><A...
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP>
P48652
B5XN94
RL3_KLEP3
50S ribosomal protein L3
Klebsiella
<M><I><G><L><V><G><K><K><V><G><M><T><R><I><F><T><E><D><G><V><S><I><P><V><T><V><I><E><V><E><A><N><R><V><T><Q><V><K><D><L><A><N><D><G><Y><R><A><I><Q><V><T><T><G><A><K><K><A><N><R><V><T><K><P><E><A><G><H><F><A><K><A><G><V><E><A><G><R><G><L><W><E><F><R><L><A><D><G><E><E><F><T><V><G><Q><N><I><S><V><E><L><F><A><D><V><K><K><V...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
B5XN94
B2JE74
TAL_PARP8
Transaldolase
Paraburkholderia
<M><T><T><A><L><D><Q><L><K><Q><Y><T><T><V><V><A><D><T><G><D><F><Q><Q><L><A><Q><Y><K><P><Q><D><A><T><T><N><P><S><L><V><L><K><A><V><Q><K><D><E><Y><K><P><L><L><E><K><T><V><R><D><H><A><S><K><P><V><G><S><I><I><D><N><L><L><I><A><F><G><T><E><I><L><K><I><V><P><G><R><V><S><T><E><V><D><A><R><L><S><F><D><T><K><A><S><I><D><K><A><H...
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP>
B2JE74
Q5WDX9
TCYP_ALKCK
Transporter of cystine TcyP
Alkalihalobacillus
<M><D><L><F><L><T><L><L><I><I><A><I><V><L><A><V><A><G><L><L><F><Y><M><Q><K><K><H><V><S><F><S><I><R><V><L><L><A><L><G><A><G><V><V><Y><G><L><L><L><Q><F><F><F><A><P><D><S><S><V><I><Q><Q><S><M><D><W><V><N><I><L><G><T><G><Y><V><R><F><L><Q><M><I><V><M><P><L><I><F><I><S><I><L><S><A><F><T><R><M><T><L><T><K><N><L><G><K><I><S><A...
Mediates uptake of L-cystine, the oxidized form of L-cysteine.<BOP>
Q5WDX9
P22494
UMUC_SALTY
Protein UmuC
Salmonella
<M><F><A><L><C><D><V><N><S><F><Y><A><S><C><E><T><V><F><R><P><D><L><C><G><R><P><V><V><V><L><S><N><N><D><G><C><V><I><A><C><S><A><E><A><K><Q><L><G><I><A><P><G><E><P><Y><F><K><Q><K><E><R><F><R><R><S><G><V><V><C><F><S><S><N><Y><E><L><Y><A><D><M><S><N><R><V><M><T><T><L><E><E><M><V><P><R><V><E><I><Y><S><I><D><E><A><F><C><D><L...
Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template.<BOP>
P22494
A4YUN8
QUEC_BRASO
Queuosine biosynthesis protein QueC
unclassified Bradyrhizobium
<M><S><E><Q><D><A><T><A><L><V><L><F><S><G><G><Q><D><S><T><T><C><L><A><W><A><L><D><R><F><A><R><V><E><T><I><G><F><S><Y><G><Q><R><H><G><I><E><L><D><C><R><A><R><L><R><D><G><I><A><Q><L><R><A><D><W><A><D><K><L><G><C><E><H><T><L><D><I><P><T><L><A><A><I><S><E><T><A><L><T><R><D><V><A><I><E><M><G><A><D><G><L><P><N><T><F><V><P><G...
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).<BOP>
A4YUN8
Q09G27
PETG_PLAOC
Cytochrome b6-f complex subunit V
Platanus
<M><V><E><V><F><L><F><G><I><V><L><G><L><I><P><I><T><L><A><G><L><F><V><T><A><Y><L><Q><Y><R><R><G><D><Q><L><D><L>
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex.<BOP>
Q09G27
A0LXM7
EFTS_GRAFK
Elongation factor Ts
Gramella
<M><A><K><I><T><A><A><E><V><N><K><L><R><K><A><T><G><A><G><M><M><D><C><K><K><A><L><V><E><A><E><G><D><F><D><G><A><I><E><L><L><R><K><K><G><Q><K><V><A><A><K><R><A><D><R><D><S><S><E><G><A><A><I><A><Q><V><N><G><D><N><T><K><G><V><I><I><S><L><N><C><E><T><D><F><V><A><K><N><D><D><F><I><K><M><A><N><N><F><A><E><I><A><L><N><Y><S><S...
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP>
A0LXM7
P0C5Z5
LPT_YERPA
thr operon attenuator
Yersinia
<M><R><Y><I><S><L><N><T><T><I><I><T><T><T><E><T><T><G><Y><G><A><G>
This protein is involved in control of the biosynthesis of threonine.<BOP>
P0C5Z5
B9LTD6
RL1_HALLT
50S ribosomal protein L1
Halorubrum
<M><A><D><T><I><Q><E><A><V><T><L><A><L><D><D><A><P><E><R><N><F><R><E><T><V><D><I><A><I><N><L><R><D><L><D><L><N><D><P><S><N><R><I><D><E><S><V><V><L><P><A><G><T><G><Q><E><T><Q><I><V><V><F><A><E><G><E><T><A><V><R><A><Q><E><V><A><D><Q><V><L><D><S><D><D><L><E><D><L><G><D><D><D><D><R><A><K><D><L><A><D><E><T><D><F><F><V><A><E...
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.<BOP>
B9LTD6
A9UL70
SWI5_XENTR
Protein SAE3 homolog
Silurana
<M><R><R><N><C><N><A><G><F><K><S><P><V><Q><S><P><S><S><S><S><S><G><R><G><S><E><Y><S><L><Q><K><E><V><S><E><L><Q><G><K><E><A><A><L><D><Q><E><I><A><Q><L><E><S><E><G><F><S><M><A><E><L><E><E><H><I><T><L><L><H><E><Y><N><E><L><K><D><V><G><Q><M><L><L><G><R><L><A><V><L><R><G><V><T><T><K><E><L><Y><A><E><F><G><M><N><L><E><D>
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.<BOP>
A9UL70
P44848
PLSC_HAEIN
Lysophosphatidic acid acyltransferase
Haemophilus
<M><L><K><L><L><R><I><F><L><V><L><I><C><C><I><L><I><C><V><L><G><T><I><Y><S><F><I><R><F><K><N><P><S><N><V><G><I><V><A><R><W><F><G><R><L><Y><P><L><F><G><L><K><V><E><H><R><I><P><Q><D><Q><K><Q><I><S><R><A><I><Y><I><G><N><H><Q><N><N><Y><D><M><V><T><I><S><Y><M><V><Q><P><R><T><V><S><V><G><K><K><S><L><I><W><I><P><F><F><G><I><L...
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.<BOP>
P44848
B7UQK0
ULAR_ECO27
HTH-type transcriptional regulator UlaR
Escherichia
<M><T><E><A><Q><R><H><Q><I><L><L><E><M><L><A><Q><L><G><F><V><T><V><E><K><V><V><E><R><L><G><I><S><P><A><T><A><R><R><D><I><N><K><L><D><E><S><G><K><L><K><K><V><R><N><G><A><E><A><I><T><Q><Q><R><P><R><W><T><P><M><N><L><H><Q><A><Q><N><H><D><E><K><V><R><I><A><K><A><A><S><Q><L><V><N><P><G><E><S><V><V><I><N><C><G><S><T><A><F><L...
Represses ulaG and the ulaABCDEF operon.<BOP>
B7UQK0
Q137R8
DCTA_RHOPS
C4-dicarboxylate transport protein
Rhodopseudomonas
<M><S><T><M><T><D><I><G><A><S><G><A><L><H><R><T><R><S><K><P><W><Y><K><V><L><Y><V><Q><V><L><I><A><I><V><L><G><V><L><L><G><W><V><S><P><H><L><A><T><N><P><W><I><K><A><L><G><D><G><F><V><K><L><I><K><M><V><I><A><P><I><I><F><C><T><V><V><S><G><I><A><H><I><Q><D><A><R><K><V><G><R><V><G><V><K><A><L><L><Y><F><E><V><V><S><S><F><A><L...
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.<BOP>
Q137R8
A8GPE1
RS17_RICAH
30S ribosomal protein S17
spotted fever group
<M><P><R><R><V><L><Q><G><V><V><I><S><S><K><A><D><K><T><V><T><V><K><V><E><R><K><F><K><H><P><I><Y><K><K><F><V><K><V><S><K><K><Y><A><A><H><D><S><E><N><K><Y><Q><E><G><D><K><V><S><I><I><E><S><R><P><I><S><K><T><K><T><W><I><V><V><N><G><E>
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP>
A8GPE1
Q9LVM9
YKT62_ARATH
ATGP1-like protein
Arabidopsis
<M><K><I><T><A><L><L><V><L><K><C><D><P><E><T><R><E><P><V><I><L><A><N><V><S><D><L><S><Q><F><G><K><F><S><F><Y><R><S><N><F><E><E><F><I><V><F><I><A><R><T><V><A><R><R><T><P><P><G><Q><R><Q><S><V><K><H><E><E><Y><K><V><H><A><Y><N><I><N><G><L><C><A><V><G><F><M><D><D><H><Y><P><V><R><S><A><F><S><L><L><N><Q><V><L><D><V><Y><Q><K><D...
Involved in the secretory pathway . Essential for membrane fusion mediated by either SYP41 or SYP61; triggers the fusion of phospholipid vesicles containing SYP41 or SYP61 and VTI12 .<BOP>
Q9LVM9
P63350
Y2022_MYCBO
Uncharacterized transporter Mb2022c
Mycobacterium tuberculosis complex
<M><R><R><P><L><D><P><R><D><I><P><D><E><L><R><R><R><L><G><L><L><D><A><V><V><I><G><L><G><S><M><I><G><A><G><I><F><A><A><L><A><P><A><A><Y><A><A><G><S><G><L><L><L><G><L><A><V><A><A><V><V><A><Y><C><N><A><I><S><S><A><R><L><A><A><R><Y><P><A><S><G><G><T><Y><V><Y><G><R><M><R><L><G><D><F><W><G><Y><L><A><G><W><G><F><V><V><G><K><T...
Probable amino-acid or metabolite transport protein.<BOP>
P63350
B4RDT4
Y369_PHEZH
Nucleoid-associated protein PHZ_c0369
Phenylobacterium
<M><K><D><L><N><S><L><M><K><Q><A><Q><A><M><Q><Q><K><L><A><D><A><Q><G><R><I><A><E><M><E><V><E><G><T><S><G><G><G><M><V><K><L><V><L><K><G><T><G><E><L><A><R><V><D><L><D><E><S><L><M><A><P><G><E><G><E><V><V><A><D><L><I><V><A><A><H><A><D><A><K><R><K><L><D><E><K><Q><A><E><V><M><R><E><A><A><G><P><F><A><G><M><P><G><M><P><K><L><F...
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
B4RDT4
Q6GF16
LEU1_STAAR
Alpha-isopropylmalate synthase
Staphylococcus
<M><S><S><H><I><Q><I><F><D><T><T><L><R><D><G><E><Q><T><P><G><V><N><F><T><F><D><E><R><L><R><I><A><L><Q><L><E><K><W><G><V><D><V><I><E><A><G><F><P><A><S><S><T><G><S><F><K><S><V><Q><A><I><A><Q><T><L><T><T><T><A><V><C><G><L><A><R><C><K><K><S><D><I><D><A><V><Y><E><A><T><K><D><A><A><K><P><V><V><H><V><F><I><A><T><S><P><I><H><L...
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP>
Q6GF16
Q7U8W5
ATPA_PARMW
F-ATPase subunit alpha
Parasynechococcus marenigrum
<M><V><S><I><R><P><D><E><I><S><A><I><L><K><Q><Q><I><E><D><Y><D><K><S><V><S><V><S><N><V><G><S><V><L><T><V><G><D><G><I><A><R><V><Y><G><L><Q><Q><A><M><A><G><E><L><L><E><F><E><D><G><T><E><G><I><A><L><N><L><E><D><D><N><V><G><A><V><L><M><G><E><G><L><G><I><Q><E><G><S><T><V><K><A><T><G><K><I><A><S><V><P><V><G><E><A><M><L><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
Q7U8W5
B0TK14
RECA_SHEHH
Recombinase A
Shewanella
<M><K><T><D><P><N><K><E><K><A><L><N><A><V><L><S><Q><I><E><K><Q><F><G><K><G><S><I><M><K><L><G><E><D><R><S><M><D><V><E><T><I><S><T><G><S><L><S><L><D><V><A><L><G><A><G><G><L><P><M><G><R><I><V><E><I><Y><G><P><E><S><S><G><K><T><T><L><T><L><E><V><I><A><A><A><Q><K><Q><G><K><T><C><A><F><I><D><A><E><H><A><L><D><P><I><Y><A><K><K...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
B0TK14
Q12QS1
ISPE_SHEDO
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Shewanella
<M><R><P><P><I><S><K><S><W><P><A><P><A><K><L><N><L><F><L><H><V><T><G><Q><R><D><D><G><Y><H><E><L><Q><T><L><F><Q><F><I><D><H><C><D><Y><L><D><F><Q><V><N><L><C><G><E><I><K><L><H><S><E><L><S><K><V><V><A><D><K><D><N><L><I><L><Q><A><A><K><S><L><Q><K><H><A><G><V><T><Q><G><A><D><I><W><L><E><K><L><L><P><M><G><G><G><L><G><G><G><S...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
Q12QS1
P34268
FLII_CAEEL
Protein flightless-1 homolog
Caenorhabditis
<M><S><T><G><V><L><Q><F><V><K><G><I><D><F><S><G><N><D><F><S><G><D><R><F><P><H><D><V><E><Q><M><T><Q><M><T><W><L><K><L><N><D><S><K><L><E><Q><V><P><D><E><L><S><R><C><A><N><L><E><H><L><Q><M><A><H><N><Q><L><I><S><V><H><G><E><L><S><D><L><P><R><L><R><S><V><I><V><R><D><N><N><L><K><T><A><G><I><P><T><D><I><F><R><M><K><D><L><T><I...
May play a key role in embryonic cellularization by interacting with both the cytoskeleton and other cellular components.<BOP>
P34268
P29706
ATPA_PROMO
Na(+)-translocating ATPase subunit alpha
Propionigenium
<M><K><I><R><P><E><E><I><S><G><I><I><K><T><E><I><E><N><Y><K><K><S><L><D><V><K><T><S><G><S><V><V><Q><V><G><D><G><I><A><R><I><Y><G><L><S><N><A><K><A><G><E><L><L><E><F><P><N><G><I><T><G><M><A><L><N><L><E><E><N><N><V><G><A><V><I><L><G><D><P><T><G><V><K><E><G><D><E><V><R><A><T><G><Q><I><A><A><V><G><A><G><E><A><L><L><G><R><V...
Produces ATP from ADP in the presence of a sodium ion gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
P29706
A8NJZ7
SCOC_BRUMA
Short coiled-coil protein homolog
Brugia
<M><V><E><I><N><C><F><R><L><M><S><T><D><T><T><V><T><N><E><T><D><N><F><P><L><V><D><D><E><S><Q><G><S><S><I><D><T><G><G><R><I><P><R><P><A><Q><P><L><P><R><D><E><S><D><D><Q><E><E><K><A><R><L><I><S><Q><V><L><E><L><Q><N><T><L><D><D><L><S><Q><R><V><D><S><V><K><E><E><S><L><K><L><R><S><E><N><Q><V><L><G><Q><Y><I><Q><N><L><M><A><S...
Positive regulator of amino acid starvation-induced autophagy.<BOP>
A8NJZ7
A5UXF9
GATA_ROSS1
Glutamyl-tRNA(Gln) amidotransferase subunit A
Roseiflexus
<M><T><L><L><H><Q><L><T><L><S><D><A><R><E><A><L><M><R><G><E><I><T><S><V><E><L><T><D><A><L><L><A><R><I><A><A><V><E><P><Q><V><R><A><F><L><T><I><D><A><E><G><A><R><A><Q><A><Q><A><A><D><A><R><R><A><A><G><D><T><S><P><L><L><G><I><P><L><G><I><K><D><V><I><S><T><Q><G><V><R><T><T><C><A><S><K><M><L><E><N><Y><V><P><V><Y><D><A><T><A...
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP>
A5UXF9
O15034
RIMB2_HUMAN
RIMS-binding protein 2
Homo
<M><R><E><A><A><E><R><R><Q><Q><L><Q><L><E><H><D><Q><A><L><A><V><L><S><A><K><Q><Q><E><I><D><L><L><Q><K><S><K><V><R><E><L><E><E><K><C><R><T><Q><S><E><Q><F><N><L><L><S><R><D><L><E><K><F><R><Q><H><A><G><K><I><D><L><L><G><G><S><A><V><A><P><L><D><I><S><T><A><P><S><K><P><F><P><Q><F><M><N><G><L><A><T><S><L><G><K><G><Q><E><S><A...
Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.<BOP>
O15034
Q8LDM2
PKSB_ARATH
Protein LESS ADHESIVE POLLEN 5
Arabidopsis
<M><G><S><I><D><A><A><V><L><G><S><E><K><K><S><N><P><G><K><A><T><I><L><A><L><G><K><A><F><P><H><Q><L><V><M><Q><E><Y><L><V><D><G><Y><F><K><T><T><K><C><D><D><P><E><L><K><Q><K><L><T><R><L><C><K><T><T><T><V><K><T><R><Y><V><V><M><S><E><E><I><L><K><K><Y><P><E><L><A><I><E><G><G><S><T><V><T><Q><R><L><D><I><C><N><D><A><V><T><E><M...
Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out seque...
Q8LDM2
A7X435
PCRB_STAA1
Glycerol-1-phosphate heptaprenyltransferase
Staphylococcus
<M><Y><D><I><K><K><W><R><H><I><F><K><L><D><P><A><K><H><I><S><D><D><D><L><D><A><I><C><M><S><Q><T><D><A><I><M><I><G><G><T><D><D><V><T><E><D><N><V><I><H><L><M><S><K><I><R><R><Y><P><L><P><L><V><L><E><I><S><N><I><E><S><V><M><P><G><F><D><F><Y><F><V><P><T><V><L><N><S><T><D><V><A><F><H><N><G><T><L><L><E><A><L><K><T><Y><G><H><S...
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1...
A7X435
Q5L3Y1
PDXT_GEOKA
Pyridoxal 5'-phosphate synthase glutaminase subunit
Geobacillus thermoleovorans group
<M><K><I><G><V><L><G><L><Q><G><A><V><R><E><H><V><R><A><I><E><A><C><G><A><E><A><V><I><V><K><K><P><E><Q><L><E><G><L><D><G><L><V><L><P><G><G><E><S><T><T><M><R><R><L><I><D><R><Y><G><L><M><E><P><L><K><Q><F><A><A><A><G><K><P><M><F><G><T><C><A><G><L><I><L><L><A><K><R><I><V><G><Y><D><E><P><H><L><G><L><M><D><I><T><V><E><R><N><S...
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP>
Q5L3Y1
Q2YEI7
RL6_FRUSA
50S ribosomal protein L6
Fructilactobacillus
<M><S><R><I><G><Y><K><T><I><V><I><P><E><G><V><T><V><T><R><D><E><D><V><I><T><V><K><G><P><K><G><E><L><S><E><T><F><S><P><D><V><A><M><N><V><N><G><N><E><I><N><F><E><P><T><G><K><Y><D><N><K><M><C><A><L><H><G><T><Q><R><A><N><L><A><N><M><I><E><G><V><E><K><G><F><N><K><T><L><K><L><V><G><V><G><Y><R><T><Q><L><K><G><S><D><L><I><L><N...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q2YEI7
Q01844
EWS_HUMAN
Ewing sarcoma breakpoint region 1 protein
Homo
<M><A><S><T><D><Y><S><T><Y><S><Q><A><A><A><Q><Q><G><Y><S><A><Y><T><A><Q><P><T><Q><G><Y><A><Q><T><T><Q><A><Y><G><Q><Q><S><Y><G><T><Y><G><Q><P><T><D><V><S><Y><T><Q><A><Q><T><T><A><T><Y><G><Q><T><A><Y><A><T><S><Y><G><Q><P><P><T><G><Y><T><T><P><T><A><P><Q><A><Y><S><Q><P><V><Q><G><Y><G><T><G><A><Y><D><T><T><T><A><T><V><T><T...
Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activati...
Q01844
Q7VQM2
RBFA_BLOFL
Ribosome-binding factor A
Candidatus Blochmannia
<M><Y><T><K><R><I><N><R><L><Q><R><I><S><Q><E><I><Q><R><K><V><A><I><I><I><H><H><K><V><H><D><P><R><V><G><L><P><T><I><S><G><V><Q><V><S><R><D><L><K><N><A><K><I><F><I><T><F><L><D><K><N><N><I><E><E><I><N><F><S><I><L><I><L><Q><K><A><S><G><F><I><R><F><L><L><A><N><S><M><N><L><R><T><V><P><V><L><L><F><K><Y><D><Y><S><L><K><E><G><I...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli...
Q7VQM2
B3EGX3
RS5_CHLL2
30S ribosomal protein S5
Chlorobium
<M><A><K><I><S><A><K><N><I><R><P><G><E><L><N><L><K><E><K><L><V><H><I><N><R><T><A><K><V><V><K><G><G><K><R><F><G><F><N><A><I><V><V><V><G><D><R><E><G><H><V><G><Y><G><L><G><K><A><N><E><V><Q><D><A><I><A><K><G><V><E><D><G><K><K><N><V><I><K><V><P><I><V><K><G><T><I><P><H><Q><V><I><A><K><Y><G><S><A><K><V><L><M><K><P><A><T><P><G...
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP>
B3EGX3
Q9RTR0
MUTL_DEIRA
DNA mismatch repair protein MutL
Deinococcus
<M><P><T><P><I><H><V><L><P><P><H><V><A><R><L><I><A><A><G><E><V><V><S><R><P><L><D><V><V><R><E><L><V><E><N><A><L><D><A><G><A><S><R><I><E><I><E><V><D><G><G><G><L><E><R><V><Q><V><R><D><N><G><S><G><I><A><A><Q><S><V><P><L><A><P><A><R><H><A><T><S><K><L><T><A><G><P><E><T><G><S><L><S><V><T><T><L><G><F><R><G><E><A><L><W><A><A><A...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
Q9RTR0
Q10PI5
ADPO3_ORYSJ
PAQR family protein ADIPOR3
Oryza sativa
<M><A><A><A><A><G><E><E><V><E><A><A><R><W><A><E><A><E><D><E><R><K><E><G><L><R><R><R><R><R><Y><G><L><V><E><Y><R><A><L><P><G><Y><M><R><D><N><E><Y><I><L><R><H><Y><R><C><E><W><P><L><P><Q><V><L><L><S><A><F><S><I><H><N><E><T><L><N><V><W><T><H><L><I><G><F><F><I><F><L><V><L><T><I><Y><T><A><T><Q><V><P><N><V><V><D><L><Q><S><L><Q...
May play a role in abiotic stress response.<BOP>
Q10PI5