accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
A1AWH8 | PURA_RUTMC | IMP--aspartate ligase | Candidatus Ruthia | <M><S><K><N><V><V><I><I><G><T><Q><W><G><D><E><G><K><G><K><V><V><D><L><I><T><D><K><V><A><S><V><V><R><F><Q><G><G><H><N><A><G><H><T><L><V><I><N><G><K><T><T><I><L><H><L><I><P><S><G><I><L><R><N><H><V><E><C><L><I><G><H><G><V><V><L><S><M><S><A><L><L><K><E><I><A><E><L><E><V><A><D><I><D><T><T><K><R><L><K><I><S><P><G><C><P><L><I... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | A1AWH8 |
O75081 | MTG16_HUMAN | Zinc finger MYND domain-containing protein 4 | Homo | <M><P><A><S><R><L><R><D><R><A><A><S><S><A><S><G><S><T><C><G><S><M><S><Q><T><H><P><V><L><E><S><G><L><L><A><S><A><G><C><S><A><P><R><G><P><R><K><G><G><P><A><P><V><D><R><K><A><K><A><S><A><M><P><D><S><P><A><E><V><K><T><Q><P><R><S><T><P><P><S><M><P><P><P><P><P><A><A><S><Q><G><A><T><R><P><P><S><F><T><P><H><T><H><R><E><D><G><P... | Isoform 2 functions as an A-kinase-anchoring protein .<BOP> | O75081 |
A0RQI7 | RL10_CAMFF | 50S ribosomal protein L10 | Campylobacter | <M><T><R><N><E><K><A><E><I><I><S><N><L><E><A><E><F><K><T><S><D><A><I><V><V><C><D><Y><K><G><L><S><V><K><K><L><E><A><L><R><N><S><A><R><E><L><N><V><K><V><Q><V><V><K><N><T><L><A><N><I><A><L><N><N><C><G><K><S><G><M><E><L><K><D><T><N><I><F><V><W><G><E><D><Q><L><A><V><T><K><V><V><A><K><F><E><E><S><N><N><E><L><F><K><I><K><T><A... | Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.<BOP> | A0RQI7 |
A5IHB4 | TRMB_LEGPC | tRNA(m7G46)-methyltransferase | Legionella | <M><Q><R><K><I><K><S><Y><V><L><R><A><G><R><I><S><N><R><Q><Q><Q><G><L><D><L><W><L><E><D><Y><E><L><K><F><D><S><P><S><P><W><N><F><A><K><E><F><G><R><H><D><A><D><T><I><V><E><I><G><F><G><M><G><T><S><L><F><T><M><A><M><N><N><P><Q><C><N><Y><L><G><I><E><V><H><K><A><G><V><G><S><L><V><A><D><L><H><E><H><Q><I><T><N><V><R><V><V><V><H... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | A5IHB4 |
Q3KM49 | TAL_CHLTA | Transaldolase | Chlamydia | <M><S><S><Q><F><D><Q><L><K><L><W><S><V><L><V><G><D><T><G><D><P><A><L><I><K><T><L><G><V><Q><D><A><T><T><N><P><S><L><I><L><K><V><A><Q><E><P><K><Y><Q><S><M><L><K><E><A><I><S><W><G><I><R><Q><N><G><D><D><V><Q><T><L><T><F><V><L><D><K><I><Q><V><N><L><G><L><E><I><L><K><H><V><P><G><R><V><S><L><E><I><D><A><R><L><S><F><N><T><E><A... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q3KM49 |
P60980 | VSTX1_GRARO | Voltage sensor toxin 1 | Grammostola | <M><K><T><S><V><F><V><L><V><L><G><L><V><L><L><F><A><V><S><F><A><T><E><M><E><E><S><A><R><E><C><G><K><F><M><W><K><C><K><N><S><N><D><C><C><K><D><L><V><C><S><S><R><W><K><W><C><V><L><A><S><P><F> | Inhibits sodium channels Nav1.7/SCN9A and potassium channels Kv11.1/KCNH2. Also binds the voltage-sensor domain of the potassium channel KvAP (from the archaeon Aeropyrum pernix) with very slow apparent binding kinetics and affects channel gating. Reaches its target by dynamically partitioning into anionic or zwitterio... | P60980 |
A5CCV6 | YQGF_ORITB | Putative pre-16S rRNA nuclease | Orientia | <M><I><I><N><S><I><S><E><F><L><Q><A><A><D><I><K><K><Q><I><L><G><I><D><F><G><E><K><K><V><G><V><A><I><S><N><I><E><H><T><V><A><M><P><L><Q><T><I><L><A><T><N><Q><D><R><V><N><K><I><Q><E><I><A><V><A><Y><N><I><G><A><I><V><I><G><L><P><F><K><L><D><G><T><E><T><S><Q><T><H><R><V><K><D><F><A><N><K><L><A><N><K><L><L><L><P><I><F><L><C... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | A5CCV6 |
B3DI94 | TM186_DANRE | Transmembrane protein 186 | Danio | <M><D><M><M><M><M><S><T><R><L><I><H><L><S><R><H><F><P><Q><Y><G><F><R><C><H><P><S><G><L><I><S><S><A><R><M><Q><Y><N><I><N><N><G><L><A><H><M><G><K><Q><M><P><N><T><S><T><H><T><T><R><I><H><P><A><S><F><S><S><D><L><A><S><R><K><Y><S><L><I><Y><A><F><P><L><I><R><G><L><R><A><L><S><R><L><K><L><L><Q><T><G><I><T><V><V><L><L><P><T><V... | May be required for efficient assembly of the mitochondrial complex I.<BOP> | B3DI94 |
Q5NRF6 | YBEY_ZYMMO | Endoribonuclease YbeY | Zymomonas | <M><I><T><V><E><A><D><I><S><D><L><W><P><E><Q><S><N><W><E><A><L><A><Q><T><A><C><Q><Q><A><V><S><V><S><A><S><D><F><L><L><A><K><D><Y><E><T><E><I><S><V><C><F><S><D><N><D><T><V><H><A><L><N><K><T><W><R><D><K><D><R><P><T><N><V><L><S><F><P><M><M><E><A><E><E><L><A><E><I><K><N><R><V><G><S><E><C><L><L><G><D><I><I><L><A><F><D><V><A... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q5NRF6 |
Q12LA0 | TIG_SHEDO | PPIase | Shewanella | <M><Q><V><S><V><E><T><T><E><G><L><G><R><R><L><T><I><S><V><P><A><E><Q><I><E><K><M><V><K><D><G><I><T><R><E><A><K><R><A><R><L><P><G><F><R><P><G><K><V><P><L><S><E><I><N><K><R><Y><G><Q><A><I><R><Q><D><V><M><G><E><V><M><Q><R><N><F><I><E><A><I><I><A><E><K><L><N><P><A><G><A><P><T><F><M><P><G><K><S><V><G><E><S><F><E><F><V><A><T... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | Q12LA0 |
Q110N2 | TATA_TRIEI | Sec-independent protein translocase protein TatA | Trichodesmium | <M><N><I><F><G><I><G><L><P><E><M><I><V><I><L><V><V><A><L><L><I><F><G><P><K><K><L><P><E><I><G><R><S><L><G><Q><A><I><N><S><F><K><A><G><A><R><D><F><E><N><E><F><K><R><E><A><K><H><L><E><E><G><V><K><V><S><T><S><A><S><E><P><E><K><V><V><D><V><S><S><A><T><N><T><N><K><N> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | Q110N2 |
D0KWI6 | TATC_HALNC | Sec-independent protein translocase protein TatC | Halothiobacillus | <M><T><E><R><D><S><S><P><E><A><D><K><N><G><L><A><D><V><V><E><E><T><G><M><A><G><F><L><G><H><L><V><E><L><R><N><R><L><L><K><G><V><L><A><V><L><V><L><F><L><I><L><F><P><F><R><N><E><L><F><T><M><L><A><D><P><L><S><R><H><M><P><A><G><S><T><M><I><A><V><E><V><A><S><P><F><F><I><P><L><K><L><T><A><L><T><A><V><F><I><A><I><P><F><L><L><Y... | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP> | D0KWI6 |
P11019 | VATE1_BOVIN | Vacuolar proton pump subunit E 1 | Bos | <M><A><L><S><D><A><D><V><Q><K><Q><I><K><H><M><M><A><F><I><E><Q><E><A><N><E><K><A><E><E><I><D><A><K><A><E><E><E><F><N><I><E><K><G><R><L><V><Q><T><Q><R><L><K><I><M><E><Y><Y><E><K><K><E><K><Q><I><E><Q><Q><K><K><I><Q><M><S><N><L><M><N><Q><A><R><L><K><V><L><R><A><R><D><D><L><I><T><D><L><L><N><E><A><K><Q><R><L><S><K><V><V><K... | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types... | P11019 |
Q2NW05 | TYPH_SODGM | TdRPase | Sodalis | <M><F><L><A><Q><E><I><I><R><K><K><R><D><G><E><P><L><S><D><E><E><I><R><F><F><I><N><G><V><Y><D><N><T><V><S><E><G><Q><I><A><A><L><A><M><T><I><F><F><H><D><M><D><L><Q><E><R><V><A><L><T><L><A><M><R><D><S><G><H><T><L><D><W><R><R><E><A><L><G><G><P><V><V><D><K><H><S><T><G><G><V><G><D><V><T><S><L><M><L><G><P><M><I><A><A><C><G><G... | The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP> | Q2NW05 |
O94265 | THI21_SCHPO | Hydroxymethylpyrimidine phosphate kinase 1 | Schizosaccharomyces | <M><I><S><T><C><I><T><V><A><G><S><D><C><S><G><G><A><G><V><Q><A><D><L><K><V><F><T><A><H><S><V><Y><G><M><S><A><V><T><A><I><T><S><Q><N><T><I><G><V><N><G><V><H><L><I><P><A><S><Y><V><E><Q><Q><I><S><A><C><L><L><D><V><H><C><E><V><M><K><T><G><M><L><F><N><Q><Q><I><L><K><V><I><V><E><S><I><D><R><F><K><I><K><K><V><V><V><D><P><L><I... | Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.<BOP> | O94265 |
O22349 | TBA3_ELEIN | Alpha-3-tubulin | Eleusine | <M><R><E><I><I><S><I><H><I><G><Q><A><G><I><Q><V><G><N><A><C><W><E><L><Y><C><L><E><H><G><I><E><P><D><G><T><M><P><S><D><T><S><V><G><V><A><H><D><A><F><N><T><F><F><S><E><T><G><S><G><K><H><V><P><R><A><I><F><V><D><L><E><P><T><V><I><D><E><V><R><T><G><S><Y><R><Q><L><F><H><P><E><Q><L><I><S><G><K><E><D><A><A><N><N><F><A><R><G><H... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | O22349 |
P93083 | TDC2_CAMAC | Tryptophan decarboxylase TDC2 | Camptotheca | <M><G><S><I><D><S><N><Y><D><T><E><S><A><G><Q><C><R><P><L><E><P><E><E><F><R><K><Q><A><H><Q><M><V><D><F><I><A><D><Y><Y><K><N><I><E><S><Y><P><V><L><S><Q><V><E><P><G><Y><L><Q><S><R><L><P><E><T><A><P><Y><R><P><E><P><F><E><S><I><L><K><D><V><H><K><D><I><I><P><G><V><T><H><W><L><S><P><N><F><F><A><Y><F><P><A><T><V><S><S><A><A><F... | Involved in the biosynthesis of tryptamine. Supplies tryptamine for the indole moiety of camptothecin (CPT), an anti-cancer monoterpene alkaloid. Represents a key step in monoterpene indole alkaloid biosynthesis. Is specific for tryptophan, and inactive against tyrosine, phenylalanine and 3,4-dihydroxyphenylalanine (do... | P93083 |
Q9S7B5 | THRC1_ARATH | Protein METHIONINE OVER-ACCUMULATOR 2 | Arabidopsis | <M><A><S><S><C><L><F><N><A><S><V><S><S><L><N><P><K><Q><D><P><I><R><R><H><R><S><T><S><L><L><R><H><R><P><V><V><I><S><C><T><A><D><G><N><N><I><K><A><P><I><E><T><A><V><K><P><P><H><R><T><E><D><N><I><R><D><E><A><R><R><N><R><S><N><A><V><N><P><F><S><A><K><Y><V><P><F><N><A><A><P><G><S><T><E><S><Y><S><L><D><E><I><V><Y><R><S><R><S... | Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.<BOP> | Q9S7B5 |
A6H2G3 | TATA_FLAPJ | Sec-independent protein translocase protein TatA | Flavobacterium | <M><G><R><L><G><V><T><E><I><L><M><I><L><A><V><V><L><L><L><F><G><G><K><K><I><P><E><L><M><K><G><L><G><S><G><L><S><E><F><K><K><A><A><K><G><D><E><V><P><D><S><K><K><D><E><T><K><E> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | A6H2G3 |
Q2YS22 | TYSY_BRUA2 | Thymidylate synthase | Brucella | <M><R><T><Y><L><D><L><L><Q><H><V><L><D><H><G><V><D><R><D><D><R><T><G><T><G><T><R><S><V><F><G><Y><Q><M><R><F><D><L><E><E><G><F><P><V><L><T><T><K><K><L><H><L><R><S><I><I><H><E><L><L><W><F><L><K><G><D><T><N><I><A><Y><L><K><E><N><G><V><T><I><W><D><E><W><A><D><E><N><G><D><L><G><P><V><Y><G><Y><Q><W><R><S><W><P><A><P><D><G><R... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | Q2YS22 |
Q00063 | THRC_ASHGO | Threonine synthase | Eremothecium | <M><S><Q><V><Y><R><S><T><R><S><S><S><E><D><T><K><S><F><E><E><A><V><I><Q><G><L><A><E><D><G><G><L><F><L><P><A><V><I><P><R><L><R><E><E><T><L><F><E><H><W><A><H><L><S><F><Q><D><L><A><M><E><I><M><K><F><Y><I><A><D><W><E><I><P><A><P><E><L><R><E><L><I><E><R><S><Y><S><S><F><R><S><E><E><V><T><P><L><R><K><N><V><T><G><D><D><E><N><L... | Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.<BOP> | Q00063 |
Q9VLN1 | WDR82_DROME | WD repeat-containing protein 82 | Sophophora | <M><K><I><K><L><I><D><S><V><V><R><S><F><K><V><A><K><I><F><R><E><N><T><D><K><I><N><A><I><D><F><A><P><N><G><E><H><L><I><S><C><S><E><D><D><Q><I><V><I><Y><D><C><E><K><G><T><Q><S><R><T><V><N><S><K><K><Y><G><V><D><L><I><H><F><T><H><A><N><N><T><A><I><H><S><S><T><K><V><D><D><T><I><R><Y><L><S><L><H><D><N><K><Y><L><R><Y><F><P><G... | Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 . Together with su(sable), part of a transcription termination checkpoint that promotes transcription termination of aberrant RNAs and their subsequent degradation by the nuclear exosome .<BOP> | Q9VLN1 |
P70327 | TBX6_MOUSE | T-box transcription factor TBX6 | Mus | <M><Y><H><P><R><E><L><Y><P><S><L><G><T><G><Y><R><L><G><H><P><Q><P><G><A><D><S><T><F><P><P><A><L><T><E><G><Y><R><Y><P><D><L><D><T><S><K><L><D><C><F><L><S><G><I><E><A><A><P><H><T><L><A><A><A><A><P><L><P><L><L><P><S><A><L><G><P><E><T><A><P><P><P><P><E><A><L><H><S><L><P><G><V><S><L><S><L><E><N><Q><E><L><W><K><E><F><S><A><V... | T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through eff... | P70327 |
P18728 | ZG53_XENLA | Gastrula zinc finger protein XlCGF53.1 | Xenopus | <M><G><M><W><E><E><A><S><D><T><G><M><K><G><K><K><K><K><K><D><K><N><E><E><E><E><E><E><R><G><K><K><E><R><M><V><N><L><T><L><E><M><I><Y><L><L><T><G><E><H><Y><I><P><R><K><K><S><D><D><G><G><A><L><H><A><P><G><S><V><I><Q><K><E><N><N><K><N><D><E><K><I><L><E><L><M><S><N><I><I><Q><L><L><T><G><E><V><A><I><R><T><H><H><V><S><I><Y><F... | May be involved in transcriptional regulation.<BOP> | P18728 |
C1CNW3 | TRHO_STRZT | tRNA hydroxylation protein O | Streptococcus | <M><A><K><D><I><R><V><L><L><Y><Y><L><Y><T><P><I><E><N><A><E><Q><F><A><A><D><H><L><A><F><C><K><S><I><G><L><K><G><R><I><L><V><A><D><E><G><I><N><G><T><V><S><G><D><Y><E><T><T><Q><K><Y><M><D><Y><V><H><S><L><P><G><M><E><D><L><W><F><K><I><D><E><E><S><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><D><F><D... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | C1CNW3 |
Q845X9 | TRPD_BURM1 | Anthranilate phosphoribosyltransferase | Burkholderia cepacia complex | <M><T><I><T><P><Q><E><A><L><Q><R><T><I><E><H><R><E><I><F><H><D><E><M><L><H><L><M><R><L><I><M><R><G><D><M><S><P><V><M><A><A><A><I><I><T><G><L><R><V><K><K><E><T><I><G><E><I><A><A><A><A><T><V><M><R><E><F><A><N><H><V><E><V><Q><D><N><S><N><F><V><D><I><V><G><T><G><G><D><G><S><H><T><F><N><I><S><T><A><S><M><F><V><T><A><A><A><G... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | Q845X9 |
B7NVN0 | TRPA_ECO7I | Tryptophan synthase alpha chain | Escherichia | <M><E><R><Y><E><S><L><F><I><R><L><K><E><R><H><E><G><A><F><V><P><F><V><T><L><G><D><P><G><I><E><Q><S><L><K><I><I><D><T><L><I><E><A><G><A><D><A><L><E><L><G><I><P><F><S><D><P><L><A><D><G><P><T><I><Q><N><A><T><L><R><A><F><A><A><G><V><T><P><A><Q><C><F><E><M><L><A><L><I><R><Q><K><H><P><T><I><P><I><G><L><L><M><Y><A><N><L><V><F... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | B7NVN0 |
Q8U094 | TRPA_PYRFU | Tryptophan synthase alpha chain | Pyrococcus | <M><F><K><D><G><S><L><I><P><Y><L><T><A><G><D><P><D><K><Q><S><T><L><N><F><L><L><A><L><D><E><Y><A><G><A><I><E><L><G><I><P><F><S><D><P><I><A><D><G><K><T><I><Q><E><S><H><Y><R><A><L><K><N><G><F><K><L><R><E><A><F><W><I><V><K><E><F><R><R><H><S><S><T><P><I><V><L><M><T><Y><Y><N><P><I><Y><R><A><G><V><R><N><F><L><A><E><A><K><A><S... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q8U094 |
Q9SLG3 | ZIP3_ARATH | ZRT/IRT-like protein 3 | Arabidopsis | <M><K><T><K><N><V><K><L><L><F><F><F><F><S><V><S><L><L><L><I><A><V><V><N><A><A><E><G><H><S><H><G><G><P><K><C><E><C><S><H><E><D><D><H><E><N><K><A><G><A><R><K><Y><K><I><A><A><I><P><T><V><L><I><A><G><I><I><G><V><L><F><P><L><L><G><K><V><F><P><S><L><R><P><E><T><C><F><F><F><V><T><K><A><F><A><A><G><V><I><L><A><T><G><F><M><H><V... | Mediates zinc uptake from the rhizosphere. May also transport other divalent cations.<BOP> | Q9SLG3 |
B3Q867 | TSAD_RHOPT | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Rhodopseudomonas | <M><T><S><E><Q><A><L><L><V><L><G><I><E><T><T><C><D><E><T><A><A><A><V><V><E><R><R><A><D><G><S><G><R><L><L><S><N><I><V><R><S><Q><T><D><E><H><A><P><F><G><G><V><V><P><E><I><A><A><R><A><H><V><D><V><L><D><G><I><I><A><A><A><M><N><E><A><G><V><A><F><A><S><L><S><G><V><A><A><A><A><G><P><G><L><I><G><G><V><I><V><G><L><T><T><A><K><A... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | B3Q867 |
Q8FHF8 | YDEP_ECOL6 | Protein YdeP | Escherichia | <M><K><K><K><I><E><S><Y><Q><G><A><A><G><G><W><G><A><V><K><S><V><A><N><A><V><R><K><Q><M><D><I><R><Q><D><V><I><A><M><F><D><M><N><K><P><E><G><F><D><C><P><G><C><A><W><P><D><P><K><H><S><A><S><F><D><I><C><E><N><G><A><K><A><I><A><W><E><V><T><D><K><Q><V><N><A><S><F><F><A><E><N><T><V><Q><S><L><L><T><W><G><D><H><E><L><E><A><A><G... | Probably involved in acid resistance.<BOP> | Q8FHF8 |
A8H738 | TRUB_SHEPA | tRNA-uridine isomerase | Shewanella | <M><A><R><R><S><R><G><R><F><I><D><G><I><V><L><L><D><K><D><T><G><M><S><S><N><F><A><L><Q><R><V><K><R><F><F><N><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><H><L><L><D><A><D><K><R><Y><L><V><T><A><K><L><G><Q><R><T><D><T><S><D><S><D><G><E><I><V><Q><T><R><E><V><N><F><T><Q><E><Q><L... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | A8H738 |
Q9NSU2 | TREX1_HUMAN | Deoxyribonuclease III | Homo | <M><G><S><Q><A><L><P><P><G><P><M><Q><T><L><I><F><F><D><M><E><A><T><G><L><P><F><S><Q><P><K><V><T><E><L><C><L><L><A><V><H><R><C><A><L><E><S><P><P><T><S><Q><G><P><P><P><T><V><P><P><P><P><R><V><V><D><K><L><S><L><C><V><A><P><G><K><A><C><S><P><A><A><S><E><I><T><G><L><S><T><A><V><L><A><A><H><G><R><Q><C><F><D><D><N><L><A><N><L... | Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini . Prevents cell-intrinsic initiation of autoimmunity . Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements . Plays a key role in ... | Q9NSU2 |
A5II09 | TRHO_LEGPC | tRNA hydroxylation protein O | Legionella | <M><K><D><I><I><I><A><S><F><Y><K><F><I><P><L><N><D><F><E><S><L><R><E><P><I><L><T><K><M><H><E><I><G><I><K><G><T><I><I><L><A><H><E><G><V><N><G><G><F><A><G><N><R><E><Q><M><N><V><F><Y><D><Y><L><R><S><D><S><R><F><A><D><L><H><F><K><E><T><Y><D><S><K><N><P><F><D><K><A><K><V><K><L><R><K><E><I><V><T><M><G><V><Q><K><V><D><P><S><Y... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | A5II09 |
Q21BZ6 | UBIG_RHOPB | 3-demethylubiquinone 3-O-methyltransferase | Rhodopseudomonas | <M><S><M><Q><S><N><S><S><D><A><S><S><A><T><V><D><P><A><E><I><A><K><F><S><R><L><S><A><Q><W><W><D><P><T><G><K><M><A><P><L><H><K><I><N><P><L><R><L><S><F><I><R><D><A><A><C><R><K><F><E><R><N><A><K><S><L><N><C><L><S><G><L><R><M><I><D><I><G><C><G><A><G><L><L><C><E><P><F><T><R><L><G><A><Q><V><I><G><V><D><P><S><A><T><N><I><A><A... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q21BZ6 |
Q49ZD7 | TRUA_STAS1 | tRNA-uridine isomerase I | Staphylococcus | <M><R><V><L><V><N><I><S><Y><Q><G><S><Q><F><L><G><F><Q><I><Q><Q><H><G><R><T><I><Q><Q><Q><F><E><K><I><L><K><R><M><H><K><H><E><V><R><I><H><P><S><S><R><T><D><R><G><V><H><A><I><E><Q><Y><F><H><F><D><T><E><L><N><I><P><E><Q><Q><W><Q><Y><A><M><N><R><A><L><P><D><D><I><Y><V><N><D><V><S><F><V><N><D><D><F><H><C><R><Y><D><C><V><G><K... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | Q49ZD7 |
A9GP90 | UREG_SORC5 | Urease accessory protein UreG | Sorangium | <M><H><D><P><G><E><H><G><H><G><R><H><D><H><D><H><D><H><D><H><V><H><D><H><D><H><D><H><D><H><V><H><G><G><G><H><R><H><A><H><E><H><E><H><A><H><E><H><A><H><G><H><E><H><G><H><A><H><A><H><A><H><A><H><A><H><E><H><A><H><G><H><T><H><E><H><W><A><H><P><G><L><F><S><E><R><D><A><P><K><D><R><D><F><S><A><R><A><F><T><V><G><I><G><G><P><V... | Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP> | A9GP90 |
A4FAI5 | Y1742_SACEN | Putative S-adenosyl-L-methionine-dependent methyltransferase SACE_1742 | Saccharopolyspora | <M><S><A><N><E><Q><W><D><I><V><S><G><V><G><I><T><A><L><A><V><A><V><A><R><A><R><E><S><R><R><D><D><R><L><I><D><D><P><Y><A><E><P><L><I><R><A><A><Q><P><P><V><P><M><S><G><D><G><G><E><A><G><A><L><W><H><E><M><T><D><Y><V><S><V><R><S><R><F><F><D><E><W><F><A><R><A><C><A><A><G><T><R><Q><A><V><V><L><A><S><G><L><D><T><R><A><F><R><L... | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP> | A4FAI5 |
A3D3E2 | TOLB_SHEB5 | Tol-Pal system protein TolB | Shewanella | <M><R><I><L><A><K><W><L><A><L><A><V><L><L><C><T><T><P><A><K><A><A><L><D><I><V><I><T><E><G><V><D><A><A><R><P><I><A><V><M><P><F><V><W><Q><G><S><G><A><A><P><Q><A><I><A><D><V><V><M><S><D><L><V><R><S><G><T><F><K><P><L><D><E><L><G><L><P><Q><R><N><I><G><T><A><A><Q><F><Q><A><N><S><W><S><S><V><G><A><E><A><L><V><L><G><T><V><K><P... | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP> | A3D3E2 |
O00124 | UBXN8_HUMAN | UBX domain-containing protein 6 | Homo | <M><A><S><R><G><V><V><G><I><F><F><L><S><A><V><P><L><V><C><L><E><L><R><R><G><I><P><D><I><G><I><K><D><F><L><L><L><C><G><R><I><L><L><L><L><A><L><L><T><L><I><I><S><V><T><T><S><W><L><N><S><F><K><S><P><Q><V><Y><L><K><E><E><E><E><K><N><E><K><R><Q><K><L><V><R><K><K><Q><Q><E><A><Q><G><E><K><A><S><R><Y><I><E><N><V><L><K><P><H><Q... | Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction.<BOP> | O00124 |
Q8EPB7 | TPX_OCEIH | Thioredoxin-dependent peroxiredoxin | Oceanobacillus | <M><S><N><V><T><F><K><N><D><P><V><T><L><L><G><A><E><K><K><V><G><D><S><A><P><D><F><T><V><L><A><N><D><L><S><K><K><H><L><S><D><Y><K><G><K><V><K><V><I><S><V><V><P><S><I><D><T><G><V><C><S><E><Q><T><R><R><F><N><Q><E><A><T><N><L><E><N><V><Q><I><L><T><I><S><M><D><L><P><F><A><Q><K><R><W><C><A><A><N><G><I><D><R><V><D><T><L><S><D... | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP> | Q8EPB7 |
B0B9D4 | TRMD_CHLT2 | tRNA [GM37] methyltransferase | Chlamydia | <M><E><I><D><I><L><S><L><F><P><D><Y><F><A><S><P><L><Q><A><T><I><L><G><R><A><I><K><Q><G><A><L><S><V><R><S><R><D><I><R><E><F><G><L><G><K><W><K><Q><V><D><D><S><P><Y><N><G><E><G><M><L><L><M><A><E><P><V><V><Q><A><I><R><S><I><R><R><K><K><S><K><V><I><Y><L><S><P><Q><G><Q><L><L><S><A><K><K><S><R><E><L><A><S><C><S><H><L><V><L><L... | Specifically methylates guanosine-37 in various tRNAs.<BOP> | B0B9D4 |
A1UU52 | TRUB_BARBK | tRNA-uridine isomerase | Bartonella | <M><S><R><Q><S><K><K><K><G><R><S><I><S><G><W><V><I><L><D><K><P><K><A><M><K><S><T><E><A><V><S><K><I><K><R><L><F><N><A><Q><K><A><G><H><A><G><T><L><D><P><L><A><S><G><L><L><P><I><A><L><G><E><A><T><K><T><V><P><Y><V><M><E><G><T><K><T><Y><H><F><H><V><A><W><G><E><E><R><S><T><D><D><L><E><G><V><V><T><K><T><S><S><K><R><P><T><Q><E... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | A1UU52 |
Q2SUP3 | THIC_BURTA | Thiamine biosynthesis protein ThiC | pseudomallei group | <M><N><A><N><P><K><F><L><S><A><D><A><R><V><D><A><A><A><V><A><P><L><P><N><S><R><K><V><Y><V><T><G><S><Q><P><D><I><R><V><P><M><R><E><I><T><Q><A><D><T><P><T><S><F><G><G><E><K><N><P><P><I><Y><V><Y><D><T><S><G><P><Y><T><D><P><D><A><K><I><D><I><R><A><G><L><P><A><L><R><Q><R><W><I><D><A><R><G><D><T><E><T><L><A><G><L><T><S><E><Y... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | Q2SUP3 |
A3PBC8 | YIDD_PROM0 | Putative membrane protein insertion efficiency factor | Prochlorococcus | <M><F><K><T><I><N><K><S><I><T><S><I><L><L><L><L><I><S><F><Y><Q><K><W><F><S><P><F><F><G><P><R><C><R><F><I><P><S><C><S><S><Y><G><Y><E><A><I><T><R><H><G><P><W><K><G><G><W><L><T><L><K><R><L><S><R><C><H><P><L><T><P><C><G><C><D><P><V><P><D> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | A3PBC8 |
Q6AQH2 | UPP_DESPS | UPRTase | Desulfotalea | <M><S><L><H><I><A><D><H><P><L><V><K><H><K><L><G><L><M><R><Q><N><D><I><S><T><K><D><F><R><A><L><A><S><E><I><A><R><L><L><T><Y><E><A><V><K><D><L><P><T><E><K><H><I><V><D><G><W><A><G><P><V><E><V><D><R><L><K><G><K><K><I><T><I><V><P><I><L><R><A><G><L><G><M><M><D><G><V><I><D><L><I><P><S><A><K><V><T><V><V><G><F><Y><R><D><E><E><T... | Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP> | Q6AQH2 |
C3L3F6 | YBEY_CLOB6 | Endoribonuclease YbeY | Clostridium | <M><I><Y><I><D><N><R><Q><N><K><I><K><V><N><E><E><F><E><N><K><I><K><E><I><I><D><Y><A><L><K><E><E><K><V><N><I><D><Y><E><I><S><V><V><F><I><D><N><N><S><I><K><E><I><N><K><D><Y><R><N><I><D><K><A><T><D><V><L><S><F><P><M><L><D><Y><E><E><G><K><V><F><K><D><V><Y><L><N><Y><E><F><D><E><S><D><L><D><E><G><N><L><I><L><G><D><I><A><L><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | C3L3F6 |
Q8BH57 | WDR48_MOUSE | USP1-associated factor 1 | Mus | <M><A><A><H><H><R><Q><N><T><A><G><R><R><K><V><Q><V><S><Y><V><I><R><D><E><V><E><K><Y><N><R><N><G><V><N><A><L><Q><L><D><P><A><L><N><R><L><F><T><A><G><R><D><S><I><I><R><I><W><S><V><N><Q><H><K><Q><D><P><Y><I><A><S><M><E><H><H><T><D><W><V><N><D><V><V><L><C><C><N><G><K><T><L><I><S><A><S><S><D><T><T><V><K><V><W><N><A><H><K><G... | Regulator of deubiquitinating complexes, which acts as a strong activator of USP1, USP12 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for... | Q8BH57 |
A6LTL5 | THIG_CLOB8 | Thiazole synthase | Clostridium | <M><K><K><D><V><L><T><L><G><G><H><E><F><S><S><R><F><I><L><G><S><G><K><Y><N><L><N><L><I><K><A><A><V><E><N><A><G><A><Q><M><I><T><L><A><L><R><R><A><N><T><S><G><G><E><N><I><L><D><F><I><P><E><G><V><T><L><L><P><N><T><S><G><A><R><N><A><E><E><A><V><R><I><A><R><L><A><R><A><M><N><C><G><D><F><V><K><V><E><I><I><H><D><S><K><Y><L><L... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | A6LTL5 |
Q21UL3 | UBIG_ALBFT | 3-demethylubiquinone 3-O-methyltransferase | Rhodoferax | <M><S><H><Q><P><Y><F><A><D><N><H><P><M><T><S><T><L><N><A><D><P><A><E><L><A><K><F><S><D><L><A><H><R><W><W><D><L><E><G><E><F><R><P><L><H><Q><I><N><P><L><R><L><E><W><I><N><H><L><C><P><V><A><G><Q><Q><V><L><D><V><G><C><G><G><G><I><L><A><D><S><M><A><R><L><G><A><Q><V><T><G><I><D><L><A><S><K><A><L><R><V><A><Q><L><H><A><L><E><A... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q21UL3 |
Q0IHY4 | TBC12_XENTR | TBC1 domain family member 12 | Silurana | <M><V><G><P><E><D><A><G><Q><G><A><V><Y><R><C><G><E><E><R><H><G><L><T><D><A><A><D><E><E><E><G><E><G><E><A><G><D><R><Q><T><D><I><L><Q><L><Y><I><S><R><P><A><I><K><M><T><N><G><D><L><N><Y><L><P><Q><G><G><A><G><E><G><D><M><P><S><A><G><D><M><H><S><L><S><T><H><K><E><D><I><K><Q><P><N><G><G><L><L><V><A><D><S><T><R><P><Q><G><C><A... | May act as a GTPase-activating protein for Rab family protein(s).<BOP> | Q0IHY4 |
Q0TNU2 | YBEY_CLOP1 | Endoribonuclease YbeY | Clostridium | <M><I><F><I><D><N><R><Q><N><K><F><E><V><T><E><E><L><T><K><K><L><E><E><V><I><S><F><V><L><K><E><E><K><V><K><E><D><C><E><V><S><L><V><F><V><D><N><E><E><I><R><G><I><N><N><E><T><R><G><I><D><R><A><T><D><V><L><S><F><P><M><I><D><Y><P><E><D><K><V><Y><K><D><V><Y><L><E><H><E><F><D><K><C><Y><F><D><G><D><E><L><I><L><G><D><I><V><L><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q0TNU2 |
A9WLN5 | UPP_RENSM | UPRTase | Renibacterium | <M><R><V><L><V><V><D><H><P><L><V><A><H><K><L><T><V><L><R><D><K><N><T><P><S><P><V><F><R><Q><L><T><E><E><L><V><T><L><L><A><Y><E><A><T><R><E><V><R><V><E><E><V><S><I><E><T><P><V><T><K><T><V><G><T><G><L><V><K><P><T><P><L><V><V><P><I><L><R><A><G><L><G><M><L><E><G><M><T><R><L><L><P><T><A><E><V><G><F><L><G><M><A><R><N><E><E><T... | Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP> | A9WLN5 |
Q7JR49 | VAS1_DROME | Vacuolar H(+) ATPase AC45 accessory subunit | Sophophora | <M><L><W><K><S><L><I><A><L><C><V><I><G><A><A><V><A><E><Q><T><P><V><F><L><W><G><A><N><S><V><A><K><P><S><L><K><T><V><S><Q><V><E><F><A><E><Q><L><A><A><L><L><E><D><H><M><V><V><A><F><E><E><N><G><L><S><S><K><D><F><L><C><S><N><S><Q><A><Q><S><C><Y><A><Q><L><Q><G><V><S><P><K><T><Y><Y><T><S><V><E><N><P><S><E><A><L><R><S><V><A><A... | Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles.<BOP> | Q7JR49 |
A9HI81 | UPPP_GLUDA | Undecaprenyl pyrophosphate phosphatase | Gluconacetobacter | <M><D><S><R><T><M><T><L><I><Q><A><I><V><I><A><I><L><Q><G><A><T><E><L><F><P><V><S><S><L><G><H><A><V><I><V><P><A><L><L><G><W><A><F><D><P><H><G><E><I><F><L><P><F><L><V><M><L><H><L><G><T><A><I><A><L><L><V><Y><F><R><N><D><W><A><A><I><F><Q><G><L><R><G><R><D><G><S><Q><R><Q><A><E><S><I><H><I><L><A><L><L><V><V><A><T><I><P><A><V... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | A9HI81 |
Q5M8X5 | TPC2L_XENTR | Trafficking protein particle complex subunit 2-like protein | Silurana | <M><A><V><C><V><A><V><I><A><K><E><N><Y><P><L><Y><I><R><S><T><P><T><E><N><Q><L><K><F><H><Y><T><V><H><T><S><L><D><V><V><D><E><K><I><S><A><M><G><K><A><V><M><D><Q><R><E><L><Y><L><G><L><L><Y><P><T><E><D><Y><K><V><Y><G><Y><V><T><N><S><K><V><K><F><V><M><V><V><D><S><S><N><T><S><L><R><D><N><E><I><R><S><M><F><R><K><L><H><N><S><Y... | May play a role in vesicular transport from endoplasmic reticulum to Golgi.<BOP> | Q5M8X5 |
Q83RF3 | YDEP_SHIFL | Protein YdeP | Shigella | <M><K><K><K><I><E><S><Y><Q><G><A><A><G><G><W><G><A><V><K><S><V><A><N><A><V><R><K><Q><M><D><I><R><H><D><V><I><A><M><F><D><M><N><K><P><E><G><F><D><C><P><G><C><A><W><P><D><P><K><N><S><A><S><F><D><I><C><E><N><G><A><K><A><I><A><W><E><V><T><D><K><Q><V><N><A><S><F><F><A><E><N><T><V><Q><S><L><L><T><W><G><D><H><E><L><E><A><A><G... | Probably involved in acid resistance.<BOP> | Q83RF3 |
Q55031 | TBP_SACSH | TATA-box factor | Saccharolobus | <M><S><N><S><A><V><S><Y><K><P><I><V><N><I><E><N><I><V><A><T><V><T><L><E><Q><S><L><D><L><Y><A><M><E><R><S><I><P><N><I><E><Y><D><P><D><Q><F><P><G><L><I><F><R><L><E><Q><P><K><V><T><A><L><I><F><K><S><G><K><M><V><V><T><G><A><K><S><T><E><E><L><I><K><A><V><K><R><I><I><K><T><L><K><K><Y><G><I><K><I><M><G><K><P><K><I><Q><I><Q><N... | General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.<BOP> | Q55031 |
B3GZ49 | TORD_ACTP7 | Chaperone protein TorD | Actinobacillus | <M><A><H><S><Q><L><L><S><S><E><E><R><L><F><C><Y><R><W><F><H><S><L><L><A><K><E><L><S><E><P><Q><L><Q><A><L><Q><A><G><Q><F><A><S><F><F><A><L><L><A><E><L><G><F><Q><P><Q><V><T><D><L><Q><N><E><L><A><K><L><T><A><Y><D><S><P><R><L><E><L><A><A><D><F><A><Q><C><F><L><L><E><G><K><L><S><A><L><P><Y><A><S><Y><Y><L><D><E><R><D><L><S><E... | Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.<BOP> | B3GZ49 |
P18734 | ZG67_XENLA | Gastrula zinc finger protein XlCGF67.1 | Xenopus | <S><D><R><K><T><V><S><C><P><E><C><G><K><C><F><T><S><R><T><Y><L><N><V><H><K><K><V><H><T><G><Q><T><Y><S><C><S><E><C><G><K><S><F><L><S><R><S><H><L><N><T><H><L><R><T><H><T><G><E><K><P><Y><S><C><S><E><C><G><K><C><F><T><S><S><A><I><L><I><T><H><K><R><I><H><T><G><E><R><P><F><S><C><Q><E><C><G><K><S><F><S><Y><R><S><V><F><M><E><H... | May be involved in transcriptional regulation.<BOP> | P18734 |
Q6INE8 | VMP1_XENLA | Vacuole membrane protein 1 | Xenopus | <M><A><E><N><G><T><D><C><E><Q><R><R><V><G><M><P><K><E><Q><N><N><G><S><F><Q><D><P><S><F><M><C><N><R><K><R><R><D><R><E><E><R><Q><S><I><V><L><W><R><K><P><L><I><T><L><Q><Y><F><I><L><E><V><L><I><N><L><K><E><W><S><V><R><L><W><H><R><R><M><M><V><V><S><V><L><L><L><L><A><V><L><S><V><A><Y><Y><I><E><G><E><H><Q><Q><C><V><Q><Y><I><E... | Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes. Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine. Required for autophagosome formation: participates in early stages of autophagosome biogenes... | Q6INE8 |
Q9Y5Q9 | TF3C3_HUMAN | Transcription factor IIIC subunit gamma | Homo | <M><S><G><F><S><P><E><L><I><D><Y><L><E><G><K><I><S><F><E><E><F><E><R><R><R><E><E><R><K><T><R><E><K><K><S><L><Q><E><K><G><K><L><S><A><E><E><N><P><D><D><S><E><V><P><S><S><S><G><I><N><S><T><K><S><Q><D><K><D><V><N><E><G><E><T><S><D><G><V><R><K><S><V><H><K><V><F><A><S><M><L><G><E><N><E><D><D><E><E><E><E><E><E><E><E><E><E><E... | Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.<BOP> | Q9Y5Q9 |
P68424 | TXH10_CYRSC | Huwentoxin-X | Cyriopagopus | <M><N><M><K><I><L><V><L><V><A><V><L><C><L><V><V><S><T><H><A><E><R><H><S><K><T><D><M><E><D><M><E><D><S><P><M><I><Q><E><R><K><C><L><P><P><G><K><P><C><Y><G><A><T><Q><K><I><P><C><C><G><V><C><S><H><N><K><C><T> | Reversibly blocks N-type calcium channels (Cav2.2/CACNA1B) in rat dorsal root ganglion cells (IC(50)=40 nM). Elicits no toxic symptoms in either vertebrates or invertebrates during a period of 48 hours post-injection, when it was assayed in vivo by direct injection into mice and cockroaches.<BOP> | P68424 |
P58453 | VARH_VIOAR | Varv peptide H | Viola | <G><L><P><V><C><G><E><T><C><F><G><G><T><C><N><T><P><G><C><S><C><E><T><W><P><V><C><S><R><N> | Probably participates in a plant defense mechanism.<BOP> | P58453 |
Q96NC0 | ZMAT2_HUMAN | Zinc finger matrin-type protein 2 | Homo | <M><A><S><G><S><G><T><K><N><L><D><F><R><R><K><W><D><K><D><E><Y><E><K><L><A><E><K><R><L><T><E><E><R><E><K><K><D><G><K><P><V><Q><P><V><K><R><E><L><L><R><H><R><D><Y><K><V><D><L><E><S><K><L><G><K><T><I><V><I><T><K><T><T><P><Q><S><E><M><G><G><Y><Y><C><N><V><C><D><C><V><V><K><D><S><I><N><F><L><D><H><I><N><G><K><K><H><Q><R><N... | Involved in pre-mRNA splicing as a component of the spliceosome.<BOP> | Q96NC0 |
C5BCI2 | THII_EDWI9 | tRNA 4-thiouridine synthase | Edwardsiella | <M><K><F><I><I><K><L><F><P><E><I><T><I><K><S><Q><S><V><R><L><R><F><I><K><I><L><T><G><N><I><R><N><V><L><K><P><L><V><E><D><V><A><V><T><R><H><W><D><H><I><E><V><R><A><K><E><E><S><R><R><D><L><V><R><D><A><L><T><R><I><P><G><I><H><H><I><L><E><V><E><D><H><P><Y><T><D><M><H><D><I><F><E><Q><T><L><A><M><Y><R><E><Q><L><E><E><K><T><F... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | C5BCI2 |
Q60493 | ZN664_CAVPO | Zinc finger protein from organ of Corti | Cavia | <M><I><Y><K><C><P><M><C><R><E><F><F><S><E><R><A><D><L><F><M><H><Q><K><V><H><T><A><E><K><P><H><K><C><D><K><C><D><K><G><F><F><H><I><S><E><L><H><I><H><W><R><D><H><T><G><E><K><V><Y><K><C><D><D><C><G><K><D><F><S><T><T><T><K><L><N><R><H><K><K><I><H><T><V><E><K><P><Y><K><C><Y><E><C><G><K><A><F><N><W><S><P><H><L><Q><I><H><M><R... | May be involved in transcriptional regulation.<BOP> | Q60493 |
P53061 | ZIP2_YEAST | Zipping up meiotic chromosomes protein 2 | Saccharomyces | <M><I><I><E><R><W><E><V><K><L><S><K><C><N><Q><N><V><G><G><Y><S><V><L><S><G><N><L><K><E><N><I><K><L><G><R><R><A><Q><K><Y><L><K><E><L><R><N><L><Q><L><K><P><L><K><I><G><G><Y><E><N><C><G><T><I><N><G><E><E><Y><F><L><E><V><I><H><I><T><S><G><R><Q><K><I><D><V><A><V><G><K><T><W><N><V><T><N><I><E><N><D><N><K><E><E><L><Q><Y><E><L... | Required for initiation of meiotic chromosome synapsis. Involved in synaptonemal complex formation, a structure that tethers a pair of homologous chromosomes along their lengths and plays a central role in recombination and homolog segregation during meiosis. Required for the normal localization of MSH4 to chromosomes.... | P53061 |
A7E305 | ZSWM8_BOVIN | Zinc finger SWIM domain-containing protein 8 | Bos | <M><E><L><M><F><A><E><W><E><D><G><E><R><F><S><F><E><D><S><D><R><F><E><E><D><S><L><C><S><F><I><S><E><A><E><S><L><C><Q><N><W><R><G><W><R><K><Q><S><A><G><P><N><S><P><T><G><G><G><G><G><G><G><S><G><G><T><R><M><R><D><G><L><V><I><P><L><V><E><L><S><A><K><Q><V><A><F><H><I><P><F><E><V><V><E><K><V><Y><P><P><V><P><E><Q><L><Q><L><R... | Substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex that promotes target-directed microRNA degradation (TDMD), a process that mediates degradation of microRNAs (miRNAs). The SCF-like E3 ubiquitin-protein ligase complex acts by catalyzing ubiquitination and subsequent degradation of AGO pro... | A7E305 |
O32583 | THIS_ECOLI | Thiamine biosynthesis protein ThiS | Escherichia | <M><Q><I><L><F><N><D><Q><A><M><Q><C><A><A><G><Q><T><V><H><E><L><L><E><Q><L><D><Q><R><Q><A><G><A><A><L><A><I><N><Q><Q><I><V><P><R><E><Q><W><A><Q><H><I><V><Q><D><G><D><Q><I><L><L><F><Q><V><I><A><G><G> | Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<BOP> | O32583 |
Q8A7D1 | TILS_BACTN | tRNA(Ile)-lysidine synthetase | Bacteroides | <M><I><Q><Q><R><V><I><R><Y><I><E><K><E><H><L><F><L><P><D><D><K><L><L><V><A><L><S><G><G><A><D><S><V><A><L><L><R><V><L><H><T><A><G><Y><Q><C><E><A><A><H><C><N><F><H><L><R><G><E><E><S><N><R><D><E><R><F><V><R><Q><L><C><Q><K><Y><G><I><R><L><H><I><T><D><F><N><T><T><Q><Y><A><T><E><K><R><I><S><I><E><M><A><A><R><E><L><R><Y><N><W... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | Q8A7D1 |
Q9KJF6 | XERC_STAAU | Tyrosine recombinase XerC | Staphylococcus | <M><N><H><I><Q><E><A><F><L><N><T><L><K><V><E><R><N><F><S><E><H><T><L><K><S><Y><Q><D><D><L><I><Q><F><N><Q><F><L><E><Q><E><H><L><Q><L><N><T><F><E><Y><R><D><A><R><N><Y><L><S><Y><L><Y><L><N><H><L><K><R><T><S><V><S><R><K><I><S><T><L><R><T><L><Y><E><Y><W><M><T><L><D><E><N><I><I><N><P><F><V><H><L><V><H><P><K><K><E><K><Y><L><P... | Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plas... | Q9KJF6 |
Q4A0A8 | TARI_STAS1 | Ribitol-5-phosphate cytidylyltransferase | Staphylococcus | <M><I><Y><A><G><I><L><A><G><G><I><G><S><R><M><G><N><V><P><L><P><K><Q><F><L><D><L><D><G><K><P><I><L><V><H><T><V><E><K><F><L><L><T><S><E><F><D><K><I><F><I><A><T><P><Q><K><W><I><S><H><T><K><D><T><L><R><K><H><H><I><T><D><D><R><I><E><V><V><Q><G><G><S><D><R><N><E><T><I><M><N><I><I><S><A><A><E><K><E><N><G><I><S><D><D><D><V><I... | Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.<BOP> | Q4A0A8 |
Q9P7B4 | YI13_SCHPO | L-allo-threonine dehydrogenase | Schizosaccharomyces | <M><S><R><L><D><G><K><T><I><L><I><T><G><A><S><S><G><I><G><K><S><T><A><F><E><I><A><K><V><A><K><V><K><L><I><L><A><A><R><R><F><S><T><V><E><E><I><A><K><E><L><E><S><K><Y><E><V><S><V><L><P><L><K><L><D><V><S><D><L><K><S><I><P><G><V><I><E><S><L><P><K><E><F><A><D><I><D><V><L><I><N><N><A><G><L><A><L><G><T><D><K><V><I><D><L><N><I... | NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L-allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisob... | Q9P7B4 |
P15120 | UROK_CHICK | Urokinase-type plasminogen activator chain B | Gallus | <M><K><L><I><I><F><L><T><V><T><L><C><T><L><V><T><G><L><D><S><V><Y><I><R><Q><Y><Y><K><L><S><H><K><H><R><P><Q><H><R><E><C><Q><C><L><N><G><G><T><C><I><T><Y><R><F><F><S><Q><I><K><R><C><L><C><P><E><G><Y><G><G><L><H><C><E><I><D><T><N><S><I><C><Y><S><G><N><G><E><D><Y><R><G><M><A><E><D><P><G><C><L><Y><W><D><H><P><S><V><I><R><W... | Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.<BOP> | P15120 |
B5EFL1 | UBIE_CITBB | Demethylmenaquinone methyltransferase | Citrifermentans | <M><Y><A><L><S><E><K><G><E><R><I><R><A><M><F><G><S><I><A><P><R><Y><D><L><L><N><R><L><L><S><L><G><I><D><R><R><W><R><R><F><A><V><K><K><I><G><L><N><G><S><G><R><V><L><D><V><A><T><G><T><G><D><V><A><L><E><I><A><S><Q><T><P><A><S><V><S><I><V><G><I><D><F><T><P><E><M><I><E><L><G><R><V><K><V><K><D><S><R><H><C><G><R><I><T><L><Q><V... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | B5EFL1 |
Q89UF8 | UREF_BRADU | Urease accessory protein UreF | Bradyrhizobium | <M><L><M><T><T><N><E><P><V><N><A><G><D><L><A><A><R><E><A><A><A><L><Y><R><L><M><T><W><L><S><P><A><F><P><V><G><G><F><S><Y><S><S><G><I><E><W><A><V><E><A><G><D><I><T><D><T><A><T><L><A><D><W><L><D><T><M><L><G><D><G><S><G><F><C><D><A><T><F><L><V><Q><A><Y><R><A><T><E><A><G><E><E><T><S><L><R><D><I><A><E><L><A><S><A><F><V><P><S... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | Q89UF8 |
Q5E2R0 | YACG_ALIF1 | DNA gyrase inhibitor YacG | Aliivibrio | <M><T><K><P><T><T><E><Q><P><T><T><V><K><C><P><T><C><Q><S><A><V><I><W><N><A><E><S><P><F><R><P><F><C><S><K><K><C><Q><M><I><D><F><G><E><W><A><D><E><E><K><S><I><P><G><A><P><D><M><S><D><S><D><G><W><S><E><D><Q><Y> | Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<BOP> | Q5E2R0 |
C5BHG1 | TSAD_EDWI9 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Edwardsiella | <M><R><I><L><G><I><E><T><S><C><D><E><T><G><I><A><I><Y><D><D><E><K><G><I><L><A><N><Q><L><Y><S><Q><I><K><L><H><A><D><Y><G><G><V><V><P><E><L><A><S><R><D><H><V><R><K><T><V><P><L><I><Q><A><A><L><R><E><A><D><L><T><P><A><D><L><D><G><V><A><Y><T><A><G><P><G><L><V><G><A><L><L><V><G><A><T><V><G><R><S><L><A><F><A><W><G><V><P><A><V... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | C5BHG1 |
Q9A6Q5 | THIC_CAUVC | Thiamine biosynthesis protein ThiC | Caulobacter | <M><N><I><Q><S><T><I><K><A><V><A><E><T><I><S><T><G><P><I><P><G><S><R><K><V><Y><Q><A><G><E><L><F><P><E><L><R><V><P><F><R><E><V><A><V><H><P><S><A><N><E><P><P><V><T><I><Y><D><P><S><G><P><Y><S><D><P><A><I><Q><I><D><I><E><K><G><L><P><R><T><R><E><A><L><V><V><A><R><G><D><V><E><E><V><A><D><P><R><Q><V><K><P><E><D><N><G><F><A><Q... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | Q9A6Q5 |
Q91507 | VSP1_PROMU | Tm-VIG | Protobothrops | <M><V><L><I><R><V><L><A><N><L><L><I><L><Q><L><S><Y><A><Q><K><S><S><E><L><V><I><G><G><D><E><C><N><I><N><E><H><P><F><L><V><L><V><Y><Y><D><D><Y><Q><C><G><G><T><L><L><N><E><E><W><V><L><T><A><A><H><C><N><G><K><D><M><E><I><Y><L><G><V><H><S><K><K><V><P><N><K><D><V><Q><R><R><V><P><K><E><K><F><F><C><D><S><S><K><T><Y><T><K><W><N... | Snake venom serine protease with strong beta-fibrinogenolytic activities, angiotensin I (AGT)-degrading activities and strong kallikrein-like activities in vitro, releasing bradykinin from kininogen (KNG1). Intravenous injection strongly lowers blood pressure in experimental rats, which may be explained by the action o... | Q91507 |
A3N0Y0 | YCIB_ACTP2 | Inner membrane-spanning protein YciB | Actinobacillus | <M><K><Q><L><L><E><F><I><P><L><I><L><F><F><T><V><Y><K><L><Y><G><V><Q><Q><A><A><I><T><L><V><I><A><T><V><I><Q><L><I><V><L><K><V><L><Y><K><K><I><E><K><S><Q><W><I><M><G><I><F><A><V><F><F><G><I><L><T><A><Y><F><N><D><L><N><F><L><K><W><K><V><T><I><I><N><G><L><F><A><A><V><L><L><V><S><Q><F><V><F><K><K><P><I><I><Q><M><L><L><G><K... | Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP> | A3N0Y0 |
A4VGU2 | XPT_PSEU5 | Xanthine phosphoribosyltransferase | Pseudomonas | <M><E><Q><L><K><D><K><I><R><S><H><G><I><V><L><S><D><R><V><L><K><V><D><A><F><L><N><H><Q><I><D><P><V><L><M><Q><A><I><G><R><E><F><A><R><R><F><R><D><D><G><I><T><K><I><V><T><I><E><A><S><G><I><A><P><A><V><M><A><G><L><E><L><G><V><P><V><I><F><A><R><K><H><Q><S><L><T><L><H><D><N><L><L><T><A><T><V><Y><S><F><T><K><Q><V><E><S><T><I... | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP> | A4VGU2 |
Q9BZM4 | ULBP3_HUMAN | Retinoic acid early transcript 1N | Homo | <M><A><A><A><A><S><P><A><I><L><P><R><L><A><I><L><P><Y><L><L><F><D><W><S><G><T><G><R><A><D><A><H><S><L><W><Y><N><F><T><I><I><H><L><P><R><H><G><Q><Q><W><C><E><V><Q><S><Q><V><D><Q><K><N><F><L><S><Y><D><C><G><S><D><K><V><L><S><M><G><H><L><E><E><Q><L><Y><A><T><D><A><W><G><K><Q><L><E><M><L><R><E><V><G><Q><R><L><R><L><E><L><A... | Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.<BOP> | Q9BZM4 |
Q9Y3C4 | TPRKB_HUMAN | TP53RK-binding protein | Homo | <M><Q><L><T><H><Q><L><D><L><F><P><E><C><R><V><T><L><L><L><F><K><D><V><K><N><A><G><D><L><R><R><K><A><M><E><G><T><I><D><G><S><L><I><N><P><T><V><I><V><D><P><F><Q><I><L><V><A><A><N><K><A><V><H><L><Y><K><L><G><K><M><K><T><R><T><L><S><T><E><I><I><F><N><L><S><P><N><N><N><I><S><E><A><L><K><K><F><G><I><S><A><N><D><T><S><I><L><I... | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine . The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group o... | Q9Y3C4 |
Q0VQH0 | UPPP_ALCBS | Undecaprenyl pyrophosphate phosphatase | Alcanivorax | <M><D><W><F><Q><A><L><V><L><A><L><I><Q><G><L><T><E><F><L><P><I><S><S><S><A><H><L><I><L><P><S><Q><I><L><G><W><P><D><Q><G><L><A><F><D><V><A><V><H><L><G><T><L><L><A><V><M><M><Y><Y><R><R><D><L><I><A><M><V><G><G><A><G><L><A><V><Q><Q><R><R><M><N><D><D><L><K><L><G><L><L><V><A><L><A><T><I><P><A><V><V><F><G><F><L><G><D><D><F><I... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q0VQH0 |
Q9I068 | TSI4_PSEAE | Immune protein Tsi4 | Pseudomonas | <M><T><T><S><S><G><S><R><I><G><G><L><L><H><A><S><L><F><S><L><L><G><L><G><L><L><L><A><G><G><F><K><T><V><E><R><Y><H><F><L><R><T><A><Q><E><A><Q><G><T><V><S><A><L><N><A><G><G><S><H><P><Q><I><D><F><T><S><V><S><G><E><R><I><S><Y><P><Q><G><G><F><I><F><G><Y><Q><V><G><E><P><V><R><V><L><Y><E><A><G><R><P><A><A><S><A><I><V><D><D><A... | Immunity protein that plays a role in preventing early activation of toxin Tse4.<BOP> | Q9I068 |
B1ICC8 | VATB_STRPI | V-ATPase subunit B | Streptococcus | <M><S><V><I><K><E><Y><R><T><A><S><E><V><V><G><P><L><M><I><V><E><Q><V><N><N><V><S><Y><N><E><L><V><E><I><Q><L><H><N><G><E><I><R><R><G><Q><V><L><E><I><H><E><D><K><A><M><V><Q><L><F><E><G><S><S><G><I><N><L><E><K><S><K><I><R><F><A><G><H><A><L><E><L><A><V><S><E><D><M><V><G><R><I><F><N><G><M><G><K><P><I><D><G><G><P><D><L><I><P... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.<BOP> | B1ICC8 |
Q05741 | TRXB_STRCL | Thioredoxin reductase | Streptomyces | <M><S><D><V><R><N><V><I><I><I><G><S><G><P><A><G><Y><T><A><A><L><Y><T><A><R><A><S><L><Q><P><L><V><F><E><G><A><V><T><A><G><G><A><L><M><N><T><T><D><V><E><N><F><P><G><F><R><D><G><I><M><G><P><D><L><M><D><N><M><R><A><Q><A><E><R><F><G><A><E><L><I><P><D><D><V><V><S><V><D><L><T><G><D><I><K><T><V><T><D><S><A><G><T><V><H><R><A><K... | Component of the thioredoxin-thioredoxin reductase system which may be involved in biosynthesis of penicillins and cephalosporins and may be important in determining the thiol-disulfide redox balance.<BOP> | Q05741 |
Q4XFJ8 | TCTP_PLACH | Translationally-controlled tumor protein homolog | Plasmodium (Vinckeia) | <M><K><V><Y><K><D><I><F><T><N><D><E><V><C><S><D><S><Y><A><Q><E><D><P><F><G><N><P><E><F><R><E><I><A><F><E><V><K><S><N><K><R><I><K><G><N><D><D><Y><G><I><A><D><N><S><E><D><A><V><E><G><M><G><A><D><V><E><H><V><I><D><I><V><D><S><F><Q><L><T><S><T><S><L><S><K><K><E><Y><S><A><Y><V><K><N><F><M><Q><R><I><L><K><H><L><E><E><K><K><P... | Involved in calcium binding and microtubule stabilization.<BOP> | Q4XFJ8 |
P62722 | VIRG_AGRT9 | Regulatory protein VirG | Agrobacterium tumefaciens complex | <M><I><V><H><P><S><R><E><N><F><S><S><A><V><N><K><G><S><D><F><R><L><K><G><E><P><L><K><H><V><L><L><V><D><D><D><V><A><M><R><H><L><I><I><E><Y><L><T><I><H><A><F><K><V><T><A><V><A><D><S><T><Q><F><T><R><V><L><S><S><A><T><V><D><V><V><V><V><D><L><N><L><G><R><E><D><G><L><E><I><V><R><N><L><A><A><K><S><D><I><P><I><I><I><I><S><G><D... | VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A.tumefaciens.<BOP> | P62722 |
A5W1B2 | UVRC_PSEP1 | Excinuclease ABC subunit C | Pseudomonas | <M><S><Q><V><F><D><A><S><A><F><L><A><T><C><S><G><R><P><G><V><Y><R><M><F><D><G><E><A><R><L><L><Y><V><G><K><A><K><N><L><K><K><R><L><A><S><Y><F><R><K><A><G><L><A><P><K><T><A><A><L><V><A><R><I><A><Q><V><E><T><T><I><T><A><N><E><T><E><A><L><L><L><E><Q><N><L><I><K><E><W><R><P><P><Y><N><I><L><L><R><D><D><K><S><Y><P><Y><V><F><L... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | A5W1B2 |
C5BB99 | TDH_EDWI9 | L-threonine 3-dehydrogenase | Edwardsiella | <M><K><A><L><S><K><L><K><A><E><E><G><I><W><M><T><D><V><P><L><P><A><L><G><H><N><D><I><M><I><K><I><R><K><A><A><I><C><G><T><D><V><H><I><Y><N><W><D><T><W><S><Q><K><T><I><P><V><P><M><V><V><G><H><E><Y><V><G><E><V><V><A><V><G><Q><E><V><R><G><F><R><I><G><D><R><V><S><G><E><G><H><I><T><C><G><H><C><R><N><C><R><A><G><R><T><H><L><C... | Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.<BOP> | C5BB99 |
Q5KWH6 | UVRC_GEOKA | Excinuclease ABC subunit C | Geobacillus thermoleovorans group | <M><N><E><R><L><K><E><K><L><A><V><L><P><E><Q><P><G><C><Y><L><M><K><D><K><H><G><T><V><I><Y><V><G><K><A><K><S><L><K><A><R><V><R><S><Y><F><T><G><T><H><D><G><K><T><Q><R><L><V><E><E><I><A><D><F><E><Y><I><V><T><S><S><N><A><E><A><L><I><L><E><M><N><L><I><K><K><H><D><P><K><Y><N><V><M><L><K><D><D><K><S><Y><P><F><I><K><I><T><A><E... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q5KWH6 |
Q6UXN9 | WDR82_HUMAN | WD repeat-containing protein 82 | Homo | <M><K><L><T><D><S><V><L><R><S><F><R><V><A><K><V><F><R><E><N><S><D><K><I><N><C><F><D><F><S><P><N><G><E><T><V><I><S><S><S><D><D><D><S><I><V><L><Y><D><C><Q><E><G><K><P><K><R><T><L><Y><S><K><K><Y><G><V><D><L><I><R><Y><T><H><A><A><N><T><V><V><Y><S><S><N><K><I><D><D><T><I><R><Y><L><S><L><H><D><N><K><Y><I><R><Y><F><P><G><H><S... | Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes . Facilitates histone H3 'Lys-4' methylation (H3K4me) via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR... | Q6UXN9 |
Q31ZU8 | YCIB_SHIBS | Inner membrane-spanning protein YciB | Shigella | <M><K><Q><F><L><D><F><L><P><L><V><V><F><F><A><F><Y><K><I><Y><D><I><Y><A><A><T><A><A><L><I><V><A><T><A><I><V><L><I><Y><S><W><V><R><F><R><K><V><E><K><M><A><L><I><T><F><V><L><V><V><V><F><G><G><L><T><L><F><F><H><N><D><E><F><I><K><W><K><V><T><V><I><Y><A><L><F><A><G><A><L><L><V><S><Q><W><V><M><K><K><P><L><I><Q><R><M><L><S><K... | Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP> | Q31ZU8 |
A3MM33 | UVRC_BURM7 | Excinuclease ABC subunit C | pseudomallei group | <M><T><S><P><D><A><P><E><S><R><F><E><P><K><P><I><L><A><Q><L><P><H><L><P><G><V><Y><R><Y><Y><D><V><Q><D><A><V><L><Y><V><G><K><A><R><D><L><K><K><R><V><S><S><Y><F><T><K><T><Q><L><S><P><R><I><A><M><M><I><T><R><I><A><R><I><E><T><T><V><T><R><S><E><A><E><A><L><L><L><E><N><N><L><I><K><A><L><A><P><R><Y><N><I><L><F><R><D><D><K><S... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | A3MM33 |
Q9WZ09 | TRPB2_THEMA | Tryptophan synthase beta chain 2 | Thermotoga | <M><R><I><V><V><N><L><K><P><E><E><I><P><K><H><W><Y><N><V><L><A><D><L><P><F><K><L><D><P><P><L><D><P><E><T><K><Q><P><I><S><P><E><K><L><S><V><I><F><P><M><S><L><I><E><Q><E><V><S><E><E><R><F><I><E><I><P><E><P><V><L><K><E><Y><A><V><Y><R><P><T><P><L><I><R><A><T><F><L><E><E><Y><L><Q><T><P><A><R><I><Y><Y><K><Y><E><G><V><S><P><T... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q9WZ09 |
E2AIS8 | TACHY_CAMFO | Tachykinin-related peptide 4 | Camponotus | <M><Q><C><D><F><R><V><H><Q><D><A><R><L><A><R><V><Y><Y><F><T><E><V><W><W><M><F><I><F><K><F><L><E><P><K><M><L><I><N><S><V><L><F><L><A><I><W><S><S><S><F><A><E><E><S><S><S><S><D><A><T><S><N><K><R><A><A><M><G><F><Q><D><M><R><G><N><K><N><L><I><P><T><S><L><E><H><N><K><L><S><K><R><T><L><M><D><F><Q><D><N><K><D><S><N><A><P><D><I... | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.<BOP> | E2AIS8 |
E0ZS45 | URED_ORYSI | Urease accessory protein D | Oryza sativa | <M><E><A><E><A><A><M><A><A><A><A><A><A><T><G><A><V><R><V><E><K><V><R><G><R><S><A><V><T><R><C><F><A><K><Y><P><L><K><L><I><A><P><S><K><A><G><R><A><S><S><G><A><A><W><L><Y><A><I><T><Y><G><G><G><I><V><S><G><D><I><I><S><C><T><V><A><V><G><D><G><C><A><A><A><M><T><T><Q><A><S><T><K><V><Y><K><A><V><D><S><K><C><S><E><Q><V><L><E><A... | Required for the maturation and activation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | E0ZS45 |
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