accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
F1QHM7
ZD23A_DANRE
Zinc finger DHHC domain-containing protein 23-A
Danio
<M><K><R><E><R><F><K><P><P><E><P><D><D><P><L><C><C><C><G><D><I><D><Q><Q><R><E><Y><C><C><C><D><C><E><E><L><D><D><A><C><E><R><L><L><R><G><E><P><D><K><P><D><V><F><S><R><F><I><S><R><M><A><D><R><L><G><V><S><C><C><T><V><G><P><L><R><L><E><L><S><V><L><P><P><M><V><L><I><P><G><L><L><R><V><A><A><I><N><C><L><L><G><V><I><I><L><T><A...
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes.<BOP>
F1QHM7
P39109
YCFI_YEAST
Yeast cadmium factor 1
Saccharomyces
<M><A><G><N><L><V><S><W><A><C><K><L><C><R><S><P><E><G><F><G><P><I><S><F><Y><G><D><F><T><Q><C><F><I><D><G><V><I><L><N><L><S><A><I><F><M><I><T><F><G><I><R><D><L><V><N><L><C><K><K><K><H><S><G><I><K><Y><R><R><N><W><I><I><V><S><R><M><A><L><V><L><L><E><I><A><F><V><S><L><A><S><L><N><I><S><K><E><E><A><E><N><F><T><I><V><S><Q><Y...
Cooperates for the ATP-dependent vacuolar transport of bilirubin and glutathione conjugates.<BOP>
P39109
Q9BTX7
TTPAL_HUMAN
Alpha-tocopherol transfer protein-like
Homo
<M><S><E><E><S><D><S><L><R><T><S><P><S><V><A><S><L><S><E><N><E><L><P><P><P><P><E><P><P><G><Y><V><C><S><L><T><E><D><L><V><T><K><A><R><E><E><L><Q><E><K><P><E><W><R><L><R><D><V><Q><A><L><R><D><M><V><R><K><E><Y><P><N><L><S><T><S><L><D><D><A><F><L><L><R><F><L><R><A><R><K><F><D><Y><D><R><A><L><Q><L><L><V><N><Y><H><S><C><R><R...
May act as a protein that binds a hydrophobic ligand.<BOP>
Q9BTX7
Q12S25
UBIB_SHEDO
Ubiquinone biosynthesis protein UbiB
Shewanella
<M><S><I><S><S><L><H><R><G><Y><Q><V><L><R><T><L><L><H><Y><G><L><D><E><L><L><A><K><D><K><R><P><K><L><F><P><L><I><R><G><C><F><F><W><I><R><N><Q><H><K><D><K><S><A><A><E><R><L><K><L><A><M><Q><E><L><G><P><V><Y><I><K><L><G><Q><M><L><S><T><R><R><D><L><L><D><D><E><W><A><Y><Q><L><A><M><L><Q><D><R><V><P><P><F><D><S><A><L><A><R><E...
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP>
Q12S25
O23401
U84A3_ARATH
Hydroxycinnamate glucosyltransferase 3
Arabidopsis
<M><D><P><S><R><H><T><H><V><M><L><V><S><F><P><G><Q><G><H><V><N><P><L><L><R><L><G><K><L><I><A><S><K><G><L><L><V><T><F><V><T><T><E><K><P><W><G><K><K><M><R><Q><A><N><K><I><Q><D><G><V><L><K><P><V><G><L><G><F><I><R><F><E><F><F><S><D><G><F><A><D><D><D><E><K><R><F><D><F><D><A><F><R><P><H><L><E><A><V><G><K><Q><E><I><K><N><L><V...
UDP-glucosyltransferase that forms glucose esters with phenylpropanoids . Glucosylates 4-coumarate, ferulate, caffeate, sinapate and cinnamate .<BOP>
O23401
Q9JKU1
TR119_RAT
Taste receptor type 2 member 19
Rattus
<M><M><E><G><H><I><L><F><F><F><L><V><V><M><V><Q><F><V><T><G><V><L><A><N><G><L><I><V><V><V><H><A><I><D><L><I><M><W><K><K><M><A><P><L><D><L><L><L><F><C><L><A><T><S><R><I><I><L><Q><L><C><I><L><F><A><Q><L><C><L><F><S><L><V><R><H><T><L><F><E><D><N><I><T><F><V><F><I><I><N><E><L><S><L><W><F><A><T><W><L><G><V><F><Y><C><A><K><I...
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.<BOP>
Q9JKU1
Q8SR53
TCPH_ENCCU
CCT-eta
Encephalitozoon
<M><N><Q><L><F><V><Q><T><E><K><I><V><D><P><R><E><G><K><L><Q><V><V><S><N><V><D><V><C><T><K><I><A><E><F><L><E><S><T><L><G><P><Y><G><M><D><K><L><F><A><G><K><E><I><V><V><T><N><D><G><A><T><I><L><K><H><M><N><I><R><H><P><V><G><R><L><L><V><A><L><S><E><S><Q><D><S><E><V><G><D><G><T><T><S><V><V><I><L><T><T><E><I><L><S><C><L><K><P...
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.<BOP>
Q8SR53
Q39PA6
TYPH_BURL3
TdRPase
Burkholderia cepacia complex
<M><F><L><P><Q><E><F><I><R><Q><K><R><N><R><Q><A><L><D><R><D><G><I><A><A><F><V><R><G><V><T><D><G><S><V><T><E><G><Q><V><A><A><F><A><M><A><V><Y><F><N><D><L><S><T><D><E><R><V><A><L><T><L><A><Q><R><D><S><G><D><V><L><D><W><H><A><L><E><L><D><G><P><V><I><D><K><H><S><T><G><G><V><G><D><V><V><S><L><M><L><G><P><M><V><A><A><C><G><G...
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP>
Q39PA6
C4ZSI8
THIM_ECOBW
4-methyl-5-beta-hydroxyethylthiazole kinase
Escherichia
<M><Q><V><D><L><L><G><S><A><Q><S><A><H><A><L><H><L><F><H><Q><H><S><P><L><V><H><C><M><T><N><D><V><V><Q><T><F><T><A><N><T><L><L><A><L><G><A><S><P><A><M><V><I><E><T><E><E><A><S><Q><F><A><A><I><A><S><A><L><L><I><N><V><G><T><L><T><Q><P><R><A><Q><A><M><R><A><A><V><E><Q><A><K><S><S><Q><T><P><W><T><L><D><P><V><A><V><G><A><L><D...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
C4ZSI8
P09642
TBA3_CHICK
Tubulin alpha-3 chain
Gallus
<A><D><Q><C><S><G><L><Q><G><F><L><V><F><H><S><F><G><G><G><T><G><S><G><F><T><S><L><L><M><E><R><L><S><V><E><Y><S><K><K><S><K><L><E><F><S><V><Y><P><D><R><Q><V><S><T><A><V><V><E><P><Y><N><S><I><L><T><T><H><T><T><L><E><H><S><D><C><S><F><M><V><D><N><E><A><I><Y><D><I><C><N><R><N><L><D><I><E><R><P><T><Y><T><N><L><N><R><L><I><G...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
P09642
B2IEW0
TRUA_BEII9
tRNA-uridine isomerase I
Beijerinckia
<M><P><R><Y><K><L><T><V><E><Y><D><G><A><S><F><V><G><W><Q><R><Q><K><N><G><L><S><V><Q><E><V><I><E><T><A><L><L><A><I><N><G><A><P><V><G><I><R><G><A><G><R><T><D><A><G><V><H><A><S><A><Q><V><A><H><A><D><L><A><R><E><W><R><P><D><V><L><R><D><A><L><N><A><H><M><R><P><A><L><V><A><V><V><A><A><E><P><V><P><E><T><F><D><A><R><F><S><A><I...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
B2IEW0
A0QKY2
Y4435_MYCA1
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4435
Mycobacterium avium complex (MAC)
<M><T><R><T><D><Q><D><S><W><D><L><A><S><S><V><G><A><T><A><T><M><V><A><A><A><R><A><L><A><S><T><G><E><R><P><I><I><N><D><P><F><A><A><P><L><V><R><A><V><G><L><D><F><F><R><R><L><V><D><G><E><V><A><P><A><D><P><Q><R><G><E><R><D><L><Q><L><E><T><D><S><I><A><V><R><T><R><F><F><D><D><F><F><T><G><A><A><R><D><G><I><R><Q><S><V><I><L><A...
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP>
A0QKY2
B6DCT4
TX402_LYCSI
Toxin-like structure LSTX-C2
Lycosa
<M><K><V><L><V><L><F><S><V><L><F><L><T><L><F><S><Y><S><S><T><E><A><I><D><E><F><D><S><D><A><E><D><D><M><L><S><L><M><A><N><E><Q><V><R><A><K><A><C><T><P><R><L><H><D><C><S><H><D><R><H><S><C><C><R><G><E><L><S><K><D><V><C><Y><C><F><Y><P><E><G><E><D><K><T><E><V><C><S><C><Q><Q><P><K><S><H><K><Y><I><E><K><V><V><D><K><A><K><T><V...
Enhances the high-affinity desensitization of human P2RX3 purinoceptors.<BOP>
B6DCT4
P57751
UGPA1_ARATH
UDP-glucose pyrophosphorylase 1
Arabidopsis
<M><A><A><T><A><T><E><K><L><P><Q><L><K><S><A><V><D><G><L><T><E><M><S><E><N><E><K><S><G><F><I><N><L><V><S><R><Y><L><S><G><E><A><Q><H><I><E><W><S><K><I><Q><T><P><T><D><E><I><V><V><P><Y><D><K><M><A><N><V><S><E><D><A><S><E><T><K><Y><L><L><D><K><L><V><V><L><K><L><N><G><G><L><G><T><T><M><G><C><T><G><P><K><S><V><I><E><V><R><D...
Converts glucose 1-phosphate to UDP-glucose, which is the major glycosyl donor for polysaccharides. Acts redundantly with UGP2 and is essential for the synthesis of sucrose, starch and cell wall, and callose deposition . Involved in the regulation of the programmed cell death (PCD) induced by the fungal toxin fumonisin...
P57751
Q9V1P5
XERA_PYRAB
Tyrosine recombinase XerA
Pyrococcus
<M><E><E><R><E><E><R><V><R><D><D><T><I><E><E><F><A><T><Y><L><E><L><E><G><K><S><R><N><T><V><R><M><Y><T><Y><Y><I><S><K><F><F><E><E><G><H><S><P><T><A><R><D><A><L><R><F><L><A><K><L><K><R><K><G><Y><S><T><R><S><L><N><L><V><I><Q><A><L><K><A><Y><F><K><F><E><G><L><D><S><E><A><E><K><L><K><T><P><K><M><P><K><T><L><P><K><S><L><T><E...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Probably involved in the resolution of chromosome dimers at the terminus of replication. Binds to the dif site.<BOP>
Q9V1P5
A5FL65
TATA_FLAJ1
Sec-independent protein translocase protein TatA
Flavobacterium
<M><G><R><L><G><L><T><E><I><L><V><I><V><G><I><V><I><L><L><F><G><G><K><K><I><P><E><L><M><K><G><L><G><S><G><I><K><E><F><K><N><A><A><K><D><D><Q><P><A><P><A><K><K><Q><E><E><E><Q><K>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
A5FL65
Q92117
TBP_PROFL
Transcription initiation factor TFIID TBP subunit
Protobothrops
<M><D><Q><N><N><S><L><P><P><Y><A><Q><G><L><A><S><P><Q><S><A><M><T><P><G><I><P><I><F><S><P><M><M><P><Y><G><T><G><L><T><P><Q><P><A><Q><S><T><N><S><L><S><I><L><E><E><Q><Q><R><Q><Q><Q><Q><A><A><A><Q><Q><S><T><S><Q><P><T><Q><A><P><S><G><Q><T><P><Q><L><F><H><S><Q><T><L><T><T><A><P><L><P><G><T><T><P><L><Y><P><S><P><M><T><P><M...
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.<BOP>
Q92117
Q8D8S3
TORA_VIBVU
Trimethylamine-N-oxide reductase
Vibrio
<M><A><I><T><R><R><S><F><L><K><G><V><A><T><T><S><A><A><S><V><I><G><P><S><L><L><A><S><A><S><A><N><A><V><E><T><T><G><T><W><K><V><S><G><S><H><W><G><A><F><R><A><H><I><Y><A><G><K><V><Q><E><I><K><P><I><E><L><D><Q><N><P><T><E><M><L><N><G><I><K><G><I><I><Y><S><P><S><R><V><R><Y><P><M><V><R><L><D><W><L><K><K><H><K><Y><S><A><D><T...
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.<BOP>
Q8D8S3
B1KR05
UBIB_SHEWM
Ubiquinone biosynthesis protein UbiB
Shewanella
<M><T><V><T><S><I><R><R><A><Y><Q><V><I><K><T><A><L><H><Y><G><L><D><E><L><I><P><S><K><V><K><P><W><Y><F><R><L><L><R><C><T><F><F><W><L><R><N><Q><H><K><D><K><V><G><G><E><R><L><K><L><V><M><Q><E><L><G><P><V><Y><I><K><F><G><Q><M><L><S><T><R><R><D><L><L><D><D><E><W><A><E><E><L><A><M><L><Q><D><R><V><P><P><F><D><S><S><I><A><R><E...
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP>
B1KR05
D0U690
XPT1_CRYNV
Xylosylphosphotransferase 1
Cryptococcus neoformans species complex
<M><P><S><T><A><L><S><P><P><S><R><P><P><A><Q><S><Y><D><S><Y><S><S><S><L><S><P><S><S><P><R><F><H><A><A><A><G><S><H><G><R><R><S><P><S><P><S><R><L><E><S><L><L><D><G><P><H><V><P><P><R><S><P><S><R><K><I><R><S><A><L><S><R><H><I><R><P><H><I><T><P><R><T><L><T><P><V><F><L><W><T><L><A><L><W><L><I><H><H><F><L><F><P><L><S><S><P><F...
Xylosylphosphotransferase that is specific for UDP-xylose as a donor and mannose as an acceptor to form a xylose-alpha-1-phosphate-6-mannose linkage. Functions in the O-glycosylation of proteins en route through the secretory pathway.<BOP>
D0U690
B4ECC9
UREF_BURCJ
Urease accessory protein UreF
Burkholderia cepacia complex
<M><T><T><T><E><L><V><A><L><L><H><L><A><S><P><A><L><P><I><G><A><Y><S><Y><S><Q><G><L><E><A><A><L><D><A><N><L><I><R><D><A><D><S><A><R><D><W><I><A><S><G><L><T><D><V><L><A><H><G><E><L><P><F><L><A><H><Q><L><A><R><W><Q><T><D><D><T><H><A><L><A><A><E><N><A><W><F><V><A><S><R><E><S><A><E><L><R><R><E><T><E><Q><M><G><W><S><L><A><Q...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
B4ECC9
B0T2Q1
THIC_CAUSK
Thiamine biosynthesis protein ThiC
unclassified Caulobacter
<M><N><V><Q><L><P><I><K><D><A><I><G><A><I><P><T><G><E><R><P><G><S><R><K><V><Y><Q><A><G><S><L><F><P><D><I><R><V><P><F><R><E><V><A><V><H><P><S><A><N><E><P><P><V><T><I><Y><D><P><S><G><P><Y><T><D><P><H><A><K><I><D><I><E><Q><G><L><E><R><S><R><E><P><W><I><I><A><R><G><D><C><E><L><V><A><T><P><R><E><V><K><P><E><D><N><G><F><A><Q...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
B0T2Q1
A7MKI9
TUSC_CROS8
tRNA 2-thiouridine synthesizing protein C
Cronobacter
<M><K><Q><V><A><F><V><F><T><Q><A><P><H><G><T><S><A><G><R><E><G><L><D><A><L><L><A><M><S><A><L><T><E><E><I><G><V><F><F><L><S><D><G><V><F><Q><I><L><P><G><Q><H><P><Q><A><V><L><S><R><D><Y><I><S><T><F><K><V><L><P><L><Y><D><I><E><R><C><Y><I><C><R><E><S><L><Q><E><R><G><L><S><E><E><H><A><F><V><I><D><V><E><A><L><D><A><A><A><L><R...
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.<BOP>
A7MKI9
Q9UUH1
VPS55_SCHPO
Vacuolar protein sorting-associated protein 55
Schizosaccharomyces
<M><S><D><L><R><K><I><I><G><L><S><S><V><L><A><V><G><F><M><L><V><I><L><S><C><A><L><F><K><N><W><Y><P><L><L><I><V><I><P><F><I><L><A><P><L><P><N><L><L><T><K><K><Y><S><T><S><H><D><F><L><Q><E><E><D><R><N><L><L><D><F><G><R><F><T><F><G><A><T><I><C><T><G><F><A><L><P><I><V><F><V><N><V><G><L><I><G><T><A><A><A><T><M><S><C><V><G><G...
Involved in protein transport from endosomes to the vacuole.<BOP>
Q9UUH1
Q68EQ9
VMP1_XENTR
Vacuole membrane protein 1
Silurana
<M><A><E><N><G><T><D><C><E><Q><R><R><V><G><M><A><K><E><Q><N><N><G><S><F><Q><D><P><S><F><L><S><D><R><K><S><R><D><R><E><E><R><Q><S><I><V><L><W><R><K><P><L><I><T><L><Q><Y><F><I><L><E><V><L><I><T><L><K><D><W><S><I><R><L><W><H><R><R><M><M><V><V><S><V><L><L><L><L><A><V><L><S><V><V><Y><Y><I><E><G><T><H><Q><Q><Y><V><Q><Y><V><E...
Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes. Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine. Required for autophagosome formation: participates in early stages of autophagosome biogenes...
Q68EQ9
Q06443
WNT5B_AMBME
Protein Wnt-5b
Ambystoma
<M><P><G><I><R><L><L><L><A><A><A><L><L><C><C><P><P><P><A><G><A><T><S><W><W><S><L><A><Q><N><P><V><Q><R><P><E><M><Y><I><I><G><A><Q><P><V><C><S><Q><L><S><S><L><S><P><G><Q><K><K><L><C><Q><L><Y><Q><D><H><M><M><Y><I><G><E><G><A><K><T><G><I><K><E><C><Q><Y><Q><F><K><Q><R><R><W><N><C><S><T><V><D><N><T><S><V><F><G><R><V><M><Q><I...
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.<BOP>
Q06443
O87948
TORA_SHEMA
Trimethylamine-N-oxide reductase
Shewanella
<M><N><R><R><D><F><L><K><G><I><A><S><S><S><F><V><V><L><G><G><S><S><V><L><T><P><L><N><A><L><A><K><A><G><I><N><E><D><E><W><L><T><T><G><S><H><F><G><A><F><K><M><K><R><K><N><G><V><I><A><E><V><K><P><F><D><L><D><K><Y><P><T><D><M><I><N><G><I><R><G><M><V><Y><N><P><S><R><V><R><Y><P><M><V><R><L><D><F><L><L><K><G><H><K><S><N><T><H...
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.<BOP>
O87948
A4F267
TM40L_RAT
Protein TOMM40-like
Rattus
<M><G><N><T><L><G><L><A><P><M><G><T><L><P><R><W><S><H><R><R><E><E><P><L><P><N><P><G><S><F><D><E><L><H><R><L><C><K><D><V><F><P><A><Q><M><E><G><V><K><L><V><V><N><K><V><L><S><S><H><F><Q><V><A><H><T><V><H><M><S><A><L><G><L><P><G><Y><H><L><H><T><A><Y><A><G><D><W><Q><L><S><P><T><E><V><F><P><T><V><V><G><D><M><D><S><S><G><S><L...
Potential channel-forming protein implicated in import of protein precursors into mitochondria.<BOP>
A4F267
P0C296
TX22_ANDCR
Toxin Acra II-2
Androctonus
<A><D><V><P><G><N><Y><P><L><N><T><N><G><N><M><Y><Y><C><T><I><L><G><E><N><E><F><C><R><K><V><C><K><V><H><G><V><K><Y><G><Y><C><F><N><S><H><C><W><C><E><Y><L><E><A><K><D><V><S><V><W><N><A><A><K><N><Y><C><K><N><P><V><G><K>
Binds to sodium channels (Nav) and affects the channel activation process.<BOP>
P0C296
Q2K3D7
TSAD_RHIEC
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Rhizobium
<M><V><P><F><M><R><I><L><G><I><E><T><S><C><D><E><T><A><A><A><V><V><E><R><N><A><E><G><H><C><N><V><L><S><D><V><V><L><S><Q><L><D><E><H><S><A><Y><G><G><V><V><P><E><I><A><A><R><A><H><V><E><A><L><D><E><L><I><E><Q><A><L><K><R><A><N><V><S><L><A><D><V><D><A><I><A><A><T><S><G><P><G><L><I><G><G><L><L><V><G><L><M><T><G><K><A><I><A...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q2K3D7
A7FXK4
YBEY_CLOB1
Endoribonuclease YbeY
Clostridium
<M><I><Y><I><D><N><R><Q><N><K><I><K><V><N><E><E><L><E><N><K><I><K><E><I><I><D><Y><A><L><K><E><E><K><V><N><I><D><Y><E><I><S><V><V><F><I><D><N><N><S><I><K><E><I><N><K><D><Y><R><N><I><D><K><A><T><D><V><L><S><F><P><M><L><D><Y><E><D><G><E><V><F><K><D><I><Y><L><N><Y><E><F><D><E><S><D><L><D><E><G><N><L><V><L><G><D><I><A><L><S...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
A7FXK4
Q21VL5
THIE_ALBFT
Thiamine-phosphate pyrophosphorylase
Rhodoferax
<M><V><G><A><S><T><L><A><H><D><V><R><L><Q><A><L><R><L><Y><L><V><T><D><Q><F><C><A><G><G><R><T><L><A><D><V><V><A><A><A><V><Q><G><G><V><T><C><V><Q><L><R><E><K><Q><L><N><T><R><D><F><L><A><Q><A><L><A><L><K><D><L><L><A><P><H><G><I><P><L><V><I><N><D><R><I><D><V><A><L><A><C><G><A><Q><G><V><H><L><G><Q><S><D><M><P><V><T><Q><A><R...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
Q21VL5
Q9KPL8
TYPH_VIBCH
TdRPase
Vibrio
<M><S><L><S><Q><A><K><Y><L><P><Q><E><I><I><R><R><K><R><D><G><E><V><L><T><N><D><E><I><N><F><F><I><Q><G><V><A><N><N><T><V><S><E><G><Q><I><A><A><F><A><M><A><I><F><F><R><E><M><T><M><P><E><R><I><A><L><T><C><A><M><R><D><S><G><M><V><I><D><W><S><H><M><N><F><D><G><P><I><V><D><K><H><S><T><G><G><V><G><D><V><T><S><L><M><L><G><P><M...
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP>
Q9KPL8
P45312
Y1677_HAEIN
Probable iron-sulfur cluster repair protein HI_1677
Haemophilus
<M><S><F><A><Q><Q><K><L><S><E><L><A><V><S><I><P><G><A><T><K><I><F><R><E><Y><D><L><D><F><C><C><G><G><S><V><L><L><E><V><A><A><Q><Q><K><N><L><N><L><A><E><I><E><K><R><L><T><D><L><Q><Q><S><K><A><E><N><N><D><K><D><W><T><S><A><S><Y><A><E><M><I><D><H><I><I><T><R><F><H><N><R><H><R><E><Q><L><P><E><L><I><T><L><A><E><K><V><E><N><I...
Di-iron-containing protein involved in the repair of iron-sulfur clusters.<BOP>
P45312
P00986
VKT2_NAJNI
Venom basic protease inhibitor II
Naja
<R><P><R><F><C><E><L><P><A><E><T><G><L><C><K><A><R><I><R><S><F><H><Y><N><R><A><A><Q><Q><C><L><E><F><I><Y><G><G><C><G><G><N><A><N><R><F><K><T><I><D><E><C><H><R><T><C><V><G>
Serine protease inhibitor.<BOP>
P00986
Q2UUJ9
TVP38_ASPOR
Golgi apparatus membrane protein tvp38
Aspergillus subgen. Circumdati
<M><P><A><D><Y><T><S><T><A><R><A><L><S><L><P><T><S><P><S><E><S><L><S><P><A><D><N><D><S><Y><P><P><W><S><H><L><A><S><G><R><S><N><P><A><H><P><S><E><R><P><T><L><W><K><Q><V><T><H><R><L><N><E><T><S><Q><R><M><M><A><I><W><R><R><L><S><F><W><Q><K><V><G><A><A><A><A><A><L><L><A><N><L><L><G><I><G><F><L><V><F><T><G><K><V><F><I><W><L...
Golgi membrane protein involved in vesicular trafficking and spindle migration.<BOP>
Q2UUJ9
A1S3Z2
TRMD_SHEAM
tRNA [GM37] methyltransferase
Shewanella
<M><W><L><G><V><I><T><L><F><P><E><M><F><R><A><I><T><D><F><G><V><T><G><R><A><I><K><N><G><L><L><E><L><H><T><W><N><P><R><D><F><T><H><D><R><H><R><T><V><D><D><R><P><Y><G><G><G><P><G><M><L><M><M><V><Q><P><L><K><D><A><I><Q><A><A><R><T><A><A><G><D><G><A><K><V><I><Y><L><S><P><Q><G><R><K><L><T><Q><R><G><A><T><E><L><A><E><T><Q><K...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
A1S3Z2
A1UQZ7
TSAD_BARBK
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Bartonella
<M><R><L><L><G><I><E><T><S><C><D><E><T><A><T><A><V><I><E><H><N><L><K><G><K><S><H><I><L><S><N><I><V><W><S><Q><I><E><D><H><A><P><Y><G><G><V><V><P><E><I><A><A><R><A><H><V><E><I><L><D><T><L><I><L><E><A><L><A><K><A><K><T><T><L><K><E><I><D><A><I><A><V><T><G><G><P><G><L><I><G><G><L><L><V><G><L><M><S><A><K><A><L><A><F><A><T><G...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
A1UQZ7
B5FDB4
YCIB_ALIFM
Inner membrane-spanning protein YciB
Aliivibrio
<M><K><Q><I><L><D><F><I><P><L><I><I><F><F><A><L><Y><K><M><Y><D><I><Y><T><A><T><G><A><L><I><I><A><T><A><I><Q><L><V><V><T><Y><A><L><Y><K><K><V><E><K><M><Q><L><I><T><F><I><M><V><T><V><F><G><G><M><T><I><F><L><H><D><D><N><F><I><K><W><K><V><T><I><V><Y><C><V><F><A><A><G><L><I><I><A><H><I><L><G><K><P><V><I><K><G><M><L><G><K><E...
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP>
B5FDB4
B3PLP1
TRPD_CELJU
Anthranilate phosphoribosyltransferase
Cellvibrio
<M><D><I><K><Q><A><L><K><K><L><V><A><S><I><D><L><S><T><E><E><M><I><S><V><M><R><I><V><M><T><G><G><A><T><P><A><Q><I><G><G><F><L><V><A><L><R><M><K><G><E><T><L><D><E><I><T><G><A><A><M><V><M><R><E><L><A><T><P><V><N><I><D><V><D><Y><L><V><D><T><C><G><T><G><G><D><G><A><N><L><F><N><L><S><T><A><S><A><F><V><V><A><A><A><G><G><R><V...
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP>
B3PLP1
Q8CFK2
TF3B_MOUSE
B-related factor 1
Mus
<M><T><G><R><V><C><R><G><C><G><G><T><D><I><E><L><D><A><A><R><G><D><A><V><C><T><G><C><G><S><V><L><E><D><N><I><I><V><S><E><V><Q><F><V><E><N><S><G><G><G><S><S><A><V><G><Q><F><V><S><L><D><G><A><G><K><T><P><T><L><G><G><G><F><H><V><N><L><G><K><E><S><R><A><Q><T><L><Q><N><G><R><R><H><I><H><H><L><G><S><Q><L><Q><L><N><Q><H><C><L...
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters.<BOP>
Q8CFK2
P0A8Y6
YIDA_ECOL6
Sugar phosphatase YidA
Escherichia
<M><A><I><K><L><I><A><I><D><M><D><G><T><L><L><L><P><D><H><T><I><S><P><A><V><K><N><A><I><A><A><A><R><A><R><G><V><N><V><V><L><T><T><G><R><P><Y><A><G><V><H><N><Y><L><K><E><L><H><M><E><Q><P><G><D><Y><C><I><T><Y><N><G><A><L><V><Q><K><A><A><D><G><S><T><V><A><Q><T><A><L><S><Y><D><D><Y><R><F><L><E><K><L><S><R><E><V><G><S><H><F...
Catalyzes the dephosphorylation of different sugar phosphates.<BOP>
P0A8Y6
V9QFG9
TXAC_STEGR
Latrodectin
Steatoda
<M><N><V><L><H><F><L><I><L><L><M><S><V><V><S><V><F><C><I><N><P><E><D><I><G><C><D><D><S><I><T><P><E><K><F><A><E><N><D><A><K><C><V><Q><C><K><E><Q><F><E><E><T><N><M><L><E><Q><C><R><E><D><C><F><K><G><K><F><F><R><S><C><V><D><H><L><S><G><A><Y><D><E><K><D><D><V><E><A><P><P><P><E>
May increase the toxicity of alpha-latrotoxin and/or other venom components. Is non-toxic to mice and to the cockroach Periplaneta americana.<BOP>
V9QFG9
Q7VKR0
UVRC_HAEDU
Excinuclease ABC subunit C
Haemophilus
<M><S><Q><F><N><A><K><A><F><L><A><D><V><P><H><L><P><G><V><Y><R><M><Y><D><A><N><Q><A><I><I><Y><V><G><K><A><K><D><L><K><K><R><L><A><S><Y><F><R><S><Q><V><A><S><K><K><I><E><A><L><V><G><N><I><H><H><I><D><T><T><I><T><H><S><E><T><E><A><L><L><L><E><H><N><Y><I><K><Q><H><Q><P><K><Y><N><V><L><L><R><D><D><K><S><Y><P><Y><L><L><L><T...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q7VKR0
P9WQ20
TREY_MYCTO
(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase
Mycobacterium tuberculosis complex
<M><A><F><P><V><I><S><T><Y><R><V><Q><M><R><G><R><S><N><G><F><G><F><T><F><A><D><A><E><N><L><L><D><Y><L><D><D><L><G><V><S><H><L><Y><L><S><P><I><L><T><A><V><G><G><S><T><H><G><Y><D><V><T><D><P><T><T><V><S><P><E><L><G><G><S><D><G><L><A><R><L><S><A><A><A><R><S><R><G><M><G><L><I><V><D><I><V><P><S><H><V><G><V><G><K><P><E><Q><N...
Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide, maltooligosyl trehalose (alpha-maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation.<BOP>
P9WQ20
A4XPW1
THIC_PSEMY
Thiamine biosynthesis protein ThiC
Pseudomonas
<M><S><A><Q><Q><Q><K><N><L><S><E><S><A><Q><V><D><Q><Q><S><V><Q><P><F><P><R><S><Q><K><V><Y><V><Q><G><S><R><P><D><I><R><V><P><M><R><E><I><S><L><D><V><T><P><T><D><F><G><G><E><I><N><A><P><V><T><V><Y><D><T><S><G><P><Y><T><D><P><N><V><T><I><D><V><R><K><G><L><S><D><V><R><S><A><W><I><E><D><R><G><D><T><E><K><L><P><G><L><S><S><E...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
A4XPW1
Q830K4
THIM_ENTFA
4-methyl-5-beta-hydroxyethylthiazole kinase
Enterococcus
<M><K><T><S><V><K><F><E><T><I><F><P><L><T><T><A><P><L><I><Q><C><I><T><N><E><I><T><C><E><S><M><A><N><A><L><L><Y><I><D><A><K><P><I><M><A><D><D><P><R><E><F><P><Q><M><F><Q><Q><T><S><A><L><V><L><N><L><G><H><L><S><Q><E><R><E><Q><S><L><L><A><A><S><D><Y><A><R><Q><V><N><K><L><T><V><V><D><L><V><G><Y><G><A><S><D><I><R><N><E><V><G...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
Q830K4
A3DHS8
UPPP_ACET2
Undecaprenyl pyrophosphate phosphatase
Acetivibrio
<M><L><E><L><I><K><A><I><F><L><G><I><V><E><G><I><T><E><W><L><P><I><S><S><T><G><H><M><I><L><V><E><E><F><I><N><M><N><L><S><D><E><F><M><E><M><F><R><V><V><I><Q><L><G><A><I><M><A><V><V><V><L><Y><W><N><K><L><F><P><F><S><F><E><D><R><I><Q><I><K><K><D><T><F><S><L><W><I><K><V><L><A><A><T><L><P><A><A><L><I><G><V><P><F><D><D><K><I...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
A3DHS8
A1U501
URED_MARN8
Urease accessory protein UreD
Marinobacter
<M><T><A><Y><Q><A><I><D><R><H><A><S><G><H><R><F><D><T><E><R><R><W><A><A><A><L><E><L><G><F><E><A><R><A><E><S><E><P><T><P><V><T><R><L><V><R><R><R><H><H><G><P><L><R><V><Q><R><P><F><Y><P><E><G><K><T><G><C><C><H><V><Y><L><L><H><P><P><G><G><L><V><S><G><D><E><L><R><I><E><A><T><V><A><E><G><G><H><A><L><L><T><T><P><A><A><A><K><L...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
A1U501
Q1GK93
YBEY_RUEST
Endoribonuclease YbeY
unclassified Ruegeria
<M><I><L><D><V><V><I><E><D><A><R><W><D><A><A><A><L><E><K><Q><A><Q><E><A><V><S><A><T><L><A><Y><L><E><L><E><D><E><D><W><E><V><T><V><L><G><C><D><D><A><R><I><A><D><L><N><A><E><F><R><E><K><P><K><P><T><N><V><L><S><W><P><A><Q><E><L><A><A><A><Q><D><G><G><Q><P><T><P><P><E><V><D><F><M><G><D><A><A><L><G><D><I><A><I><S><Y><D><T><C...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
Q1GK93
P0C6A0
ZGLP1_HUMAN
GATA-like protein 1
Homo
<M><T><E><P><Q><V><G><C><V><A><C><P><R><V><H><K><E><P><A><Q><V><G><T><P><W><P><A><K><P><R><S><H><P><R><K><R><D><P><T><A><L><L><P><R><S><L><W><P><A><C><Q><E><S><V><T><A><L><C><F><L><Q><E><T><V><E><R><L><G><Q><S><P><A><Q><D><T><P><V><L><G><P><C><W><D><P><M><A><L><G><T><Q><G><R><L><L><L><D><R><D><S><K><D><T><Q><T><R><I><S...
Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed b...
P0C6A0
Q9ZM59
TATC_HELPJ
Sec-independent protein translocase protein TatC
Helicobacter
<M><F><E><D><L><K><P><H><L><Q><E><L><R><K><R><L><M><V><S><V><G><T><I><L><V><A><F><L><G><C><F><H><F><W><K><N><I><F><E><F><V><K><N><S><Y><K><G><T><L><I><Q><L><S><P><I><E><G><V><M><V><A><V><K><I><S><F><S><A><A><I><V><I><S><M><P><I><I><F><W><Q><L><W><L><F><I><A><P><G><L><Y><K><N><E><K><K><V><I><L><P><F><V><F><F><G><S><G><M...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP>
Q9ZM59
A4WMQ7
UPP_PYRAR
UPRTase
Pyrobaculum
<M><P><V><R><I><I><D><H><V><Y><A><Q><Y><L><L><T><R><L><R><D><K><N><T><G><S><L><D><F><R><K><G><L><V><R><L><G><R><I><I><G><Y><E><L><V><K><T><F><P><F><R><Y><V><E><V><E><T><P><L><G><R><A><V><G><V><D><I><I><G><L><D><K><V><V><I><V><Q><I><L><R><A><A><M><P><L><V><E><G><L><V><K><A><F><P><N><A><R><L><G><V><V><A><A><R><R><K><E><E...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
A4WMQ7
B1LN84
THIM_ECOSM
4-methyl-5-beta-hydroxyethylthiazole kinase
Escherichia
<M><Q><V><D><L><L><S><S><A><Q><S><A><H><A><L><H><L><F><H><K><H><S><P><L><V><H><C><M><T><N><D><V><V><Q><T><F><T><A><N><T><L><L><A><L><G><A><S><P><A><M><V><I><E><T><E><E><A><S><Q><F><A><A><I><A><S><A><L><L><I><N><V><G><T><L><T><Q><P><R><A><Q><A><M><R><A><A><V><E><Q><A><K><R><S><Q><T><P><W><T><L><D><P><V><A><V><G><A><L><D...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
B1LN84
P56495
TSHR_SHEEP
Thyroid-stimulating hormone receptor
Ovis
<M><R><P><T><P><L><L><R><L><A><L><L><L><V><L><P><S><S><L><W><G><E><R><C><P><S><P><P><C><E><C><R><Q><E><D><D><F><R><V><T><C><K><D><I><Q><R><I><P><S><L><P><P><S><T><Q><T><L><K><F><I><E><T><H><L><K><T><I><P><S><R><A><F><S><N><L><P><N><I><S><R><I><Y><L><S><I><D><A><T><L><Q><Q><L><E><S><H><S><F><Y><N><L><S><K><V><T><H><I><E...
Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.<BOP...
P56495
P20352
TF_MOUSE
Coagulation factor III
Mus
<M><A><I><L><V><R><P><R><L><L><A><A><L><A><P><T><F><L><G><C><L><L><L><Q><V><I><A><G><A><G><I><P><E><K><A><F><N><L><T><W><I><S><T><D><F><K><T><I><L><E><W><Q><P><K><P><T><N><Y><T><Y><T><V><Q><I><S><D><R><S><R><N><W><K><N><K><C><F><S><T><T><D><T><E><C><D><L><T><D><E><I><V><K><D><V><T><W><A><Y><E><A><K><V><L><S><V><P><R><R...
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<BOP>
P20352
P0C1X4
TUXA_POLAB
Turripeptide PaIAb
Polystira
<R><K><R><L><F><Y><R><Y><Y><S><H><P><G><N><Y><M><Y><L><G><H><Y><G><R><Y><Y><N><M><L><H><N><C><N><A><M><L><L><A><H><Q><M><Q><A><M><R><R><Y><Q><H><R><M><R><V><K><Q><M><Y><R><R><I><K><M><K><Q><M><Y><R><H><M><K><W><M><G><M><Y><R><Q><A><K><A><A><R><L><R><C><I>
Is lethal to drosophila larvae.<BOP>
P0C1X4
Q7XA86
ZDH11_ARATH
Zinc finger DHHC domain-containing protein At3g51390
Arabidopsis
<M><G><V><C><C><P><F><L><Q><P><W><D><R><A><R><D><Q><C><L><L><N><L><P><C><L><S><D><P><V><R><R><S><S><L><L><L><K><L><A><L><V><A><L><H><L><V><F><I><G><F><L><F><L><F><D><A><E><F><I><E><K><T><K><R><D><P><W><Y><M><G><C><Y><I><L><L><F><S><A><T><L><L><Q><Y><F><V><T><S><G><S><S><P><G><Y><V><V><D><A><M><R><D><V><C><E><A><S><A><M...
S-acyltransferase involved in protein lipid modification. Catalyzes the palmitoylation of proteins peripheral or integral to the tonoplast. Required for the tonoplast localization of CBL2, CBL3 and CBL6, but not for the plasma membrane localization of CBL9, for the endosome localization of RABF1 or for the endomembrane...
Q7XA86
Q8I8A2
TCTP_SCHHA
Translationally-controlled tumor protein homolog
Schistosoma
<M><N><F><R><E><E><R><Y><D><T><I><M><F><T><D><S><H><C><P><R><V><V><A><D><F><F><Y><E><V><E><S><R><F><T><T><A><S><S><K><V><D><G><R><L><I><G><A><N><P><S><G><E><G><E><D><D><E><D><V><D><D><T><S><E><R><V><I><D><L><V><H><A><N><G><F><I><S><V><P><Y><D><L><K><S><Y><K><A><Q><L><K><S><Y><L><K><A><I><K><E><R><L><Q><K><T><V><P><D><K...
Involved in calcium binding and microtubule stabilization.<BOP>
Q8I8A2
Q9I0D9
TSI2_PSEAE
Anti-toxin protein Tsi2
Pseudomonas
<M><N><L><K><P><Q><T><L><M><V><A><I><Q><C><V><A><A><R><T><R><E><L><D><A><Q><L><Q><N><D><D><P><Q><N><A><A><E><L><E><Q><L><L><V><G><Y><D><L><A><A><D><D><L><K><N><A><Y><E><Q><A><L><G><Q><Y><S><G><L><P><P><Y><D><R><L><I><E><E><P><A><S>
Immunity protein that plays a role in preventing early activation of toxin Tse2. Binds to a large surface of Tse2 and thereby occludes the active site to specifically inhibits Tse2.<BOP>
Q9I0D9
B1WR77
TRMFO_CROS5
Folate-dependent tRNA(M-5-U54)-methyltransferase
Crocosphaera subtropica
<M><T><E><S><T><A><K><V><Q><V><I><G><G><G><L><A><G><T><E><A><A><W><Q><V><A><Q><A><G><I><P><V><I><L><H><E><M><R><P><I><R><T><S><P><A><H><H><S><Q><E><L><A><E><L><V><C><S><N><S><F><G><A><M><S><S><N><R><A><A><G><L><L><H><E><E><L><R><R><L><N><S><I><I><I><Q><T><A><D><K><H><A><V><P><A><G><G><A><L><A><V><D><R><G><V><F><S><H><Q...
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.<BOP>
B1WR77
Q4LCT0
TXA8_ANDAU
Peptide AaF1CA8
Androctonus
<M><M><K><L><M><L><F><S><I><I><V><I><L><F><S><L><I><G><S><I><H><G><A><D><V><P><G><N><Y><P><L><D><S><S><D><D><T><Y><L><C><A><P><L><G><E><N><P><F><C><I><K><I><C><R><K><H><G><V><K><Y><G><Y><C><Y><A><F><Q><C><W><C><E><Y><L><E><D><K><N><V><K><I>
Inhibits the vertebrate potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3 in vitro with an IC(50) of 5.3 nM and 50.0 nM respectively.<BOP>
Q4LCT0
Q92MK1
UBIG_RHIME
3-demethylubiquinone 3-O-methyltransferase
Sinorhizobium
<M><S><E><T><A><R><T><T><I><D><Q><S><E><V><D><R><F><S><A><M><A><A><E><W><W><D><P><T><G><K><F><R><P><L><H><K><F><N><P><V><R><L><T><Y><I><R><D><R><V><S><E><H><F><G><R><D><A><K><S><R><Q><P><L><E><G><L><R><V><L><D><I><G><C><G><G><G><L><L><S><E><P><M><A><R><M><G><A><D><V><V><G><A><D><A><S><E><K><N><I><G><I><A><R><T><H><A><A...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
Q92MK1
O60830
TI17B_HUMAN
Mitochondrial import inner membrane translocase subunit Tim17-B
Homo
<M><E><E><Y><A><R><E><P><C><P><W><R><I><V><D><D><C><G><G><A><F><T><M><G><V><I><G><G><G><V><F><Q><A><I><K><G><F><R><N><A><P><V><G><I><R><H><R><L><R><G><S><A><N><A><V><R><I><R><A><P><Q><I><G><G><S><F><A><V><W><G><G><L><F><S><T><I><D><C><G><L><V><R><L><R><G><K><E><D><P><W><N><S><I><T><S><G><A><L><T><G><A><V><L><A><A><R><S...
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.<BOP>
O60830
Q5RAM9
ZN664_PONAB
Zinc finger protein 664
Pongo
<M><I><Y><K><C><P><M><C><R><E><F><F><S><E><R><A><D><L><F><M><H><Q><K><I><H><T><A><E><K><P><H><K><C><D><K><C><D><K><G><F><F><H><I><S><E><L><H><I><H><W><R><D><H><T><G><E><K><V><Y><K><C><D><D><C><G><K><D><F><S><T><T><T><K><L><N><R><H><K><K><I><H><T><V><E><K><P><Y><K><C><Y><E><C><G><K><A><F><N><W><S><S><H><L><Q><I><H><M><R...
May be involved in transcriptional regulation.<BOP>
Q5RAM9
A9VJW3
TRPA_BACMK
Tryptophan synthase alpha chain
Bacillus cereus group
<M><G><V><E><K><I><I><A><A><F><E><N><G><K><K><A><F><I><P><Y><V><M><G><G><D><G><G><L><E><K><L><K><E><R><I><R><F><L><D><E><A><G><A><S><I><V><E><I><G><I><P><F><S><D><P><V><A><D><G><P><T><I><Q><R><A><G><K><R><A><L><D><S><G><V><T><L><K><G><I><F><Q><A><L><I><E><V><R><Q><E><V><Q><I><P><F><V><L><M><T><Y><L><N><P><V><L><A><F><G...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
A9VJW3
Q1MND5
TRPA_RHIL3
Tryptophan synthase alpha chain
Rhizobium
<M><T><A><R><M><D><K><R><F><A><E><L><K><A><E><G><R><P><A><L><V><T><Y><F><M><G><G><D><P><D><Y><D><T><S><L><G><I><M><K><A><L><P><E><A><G><S><D><I><I><E><L><G><M><P><F><S><D><P><M><A><D><G><P><A><I><Q><L><A><G><Q><R><A><L><K><G><G><Q><T><L><K><K><T><L><Q><L><A><A><D><F><R><K><T><N><D><A><T><P><I><V><M><M><G><Y><Y><N><P><I...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q1MND5
Q7NZD3
UBIE_CHRVO
Demethylmenaquinone methyltransferase
Chromobacterium
<M><D><K><T><T><H><F><G><Y><K><T><V><A><E><S><E><K><A><G><K><V><A><E><V><F><H><S><V><A><S><K><Y><D><V><M><N><D><L><M><S><G><G><L><H><R><V><W><K><H><F><T><L><T><T><S><G><V><R><A><G><D><K><V><L><D><I><A><G><G><T><G><D><L><S><R><G><W><A><K><R><V><G><K><T><G><E><V><W><L><T><D><I><N><S><S><M><L><T><V><G><R><D><R><L><L><D><E...
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP>
Q7NZD3
Q9PI55
THIC_CAMJE
Thiamine biosynthesis protein ThiC
Campylobacter
<M><K><T><Q><M><N><Y><A><K><E><G><I><F><T><K><E><M><Q><I><V><A><Q><K><E><N><L><S><K><D><F><L><L><E><N><I><A><C><G><K><I><I><I><P><A><N><I><N><H><K><S><L><D><P><N><G><I><G><F><G><L><R><T><K><V><N><V><N><L><G><V><S><N><D><C><V><D><Y><S><E><E><M><K><K><V><E><L><A><H><K><F><G><I><E><A><I><M><D><L><S><N><Y><G><K><T><S><R><F...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
Q9PI55
A1U1Q4
TIG_MARN8
PPIase
Marinobacter
<M><Q><V><S><V><E><T><T><S><N><I><E><R><R><M><T><I><G><V><P><A><Q><E><I><D><Q><A><V><Q><K><R><L><Q><E><T><A><R><T><V><R><L><N><G><F><R><P><G><K><V><P><M><S><V><V><K><R><R><F><G><D><S><I><R><Q><E><V><V><G><E><A><M><R><D><N><Y><I><K><A><L><Q><E><Q><D><I><N><P><A><G><W><P><K><L><E><P><K><T><M><E><E><G><K><D><L><E><F><V><A...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A1U1Q4
Q17YL7
UVRB_HELAH
Excinuclease ABC subunit B
Helicobacter
<M><P><L><F><D><L><K><S><P><Y><S><L><A><G><D><Q><P><Q><A><I><D><T><L><T><K><S><L><K><N><K><N><H><Y><Q><T><L><V><G><V><T><G><S><G><K><T><Y><T><M><A><N><I><I><A><Q><T><N><K><P><T><L><I><M><S><H><N><K><T><L><C><A><Q><L><Y><S><E><F><K><A><F><F><P><H><N><R><V><E><Y><F><I><S><H><F><D><Y><Y><Q><P><E><S><Y><I><P><R><R><D><L><F...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
Q17YL7
Q9TSV6
VATG2_PIG
Vacuolar proton pump subunit G 2
Sus
<M><A><S><Q><S><Q><G><I><Q><Q><L><L><Q><A><E><K><R><A><A><E><K><V><A><D><A><R><K><R><K><A><R><R><L><K><Q><A><K><E><E><A><Q><M><E><V><E><Q><Y><R><R><E><R><E><Q><E><F><Q><S><K><Q><Q><A><A><M><G><S><Q><G><N><L><S><A><E><V><E><Q><A><T><R><R><Q><V><Q><G><M><Q><S><S><Q><Q><R><N><R><E><R><V><L><A><Q><L><L><G><M><V><C><D><V><R...
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types,...
Q9TSV6
Q6G9W1
XERC_STAAS
Tyrosine recombinase XerC
Staphylococcus
<M><N><H><I><Q><E><A><F><L><N><T><L><K><V><E><R><N><F><S><E><H><T><L><K><S><Y><Q><D><D><L><I><Q><F><N><Q><F><L><E><Q><E><H><L><Q><L><K><T><F><E><Y><R><D><A><R><N><Y><L><S><Y><L><Y><S><N><H><L><K><R><T><S><V><S><R><K><I><S><T><L><R><T><F><Y><E><Y><W><M><T><L><D><E><N><I><I><N><P><F><V><Q><L><V><H><P><K><K><E><K><Y><L><P...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plas...
Q6G9W1
B0RZV0
THII_FINM2
tRNA 4-thiouridine synthase
Finegoldia
<M><L><D><W><Y><I><S><V><S><F><G><E><L><T><L><K><G><K><N><R><H><T><F><E><K><R><A><I><S><K><I><L><D><A><I><S><D><Y><K><I><E><E><Y><Y><Q><E><Q><G><K><L><Y><I><K><A><D><V><N><D><F><D><E><I><I><D><H><I><K><K><V><F><G><I><V><Y><I><S><P><C><V><K><C><E><K><T><V><E><S><M><Q><D><G><V><L><K><I><I><E><G><K><I><I><K><D><K><L><Q><T...
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt...
B0RZV0
Q2G6V6
TYSY_NOVAD
Thymidylate synthase
Novosphingobium
<M><S><I><L><R><D><S><G><R><H><Y><E><W><Q><Y><L><D><L><M><R><R><I><W><E><H><G><D><E><R><V><D><R><T><G><V><G><T><R><S><V><F><G><A><E><L><R><F><D><L><S><D><G><R><M><P><L><L><T><T><K><R><V><Y><W><K><T><A><T><R><E><F><L><W><F><L><T><G><N><T><N><I><R><P><L><C><A><Q><G><V><E><I><W><T><D><W><P><L><D><R><Y><R><K><E><T><G><D><D...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
Q2G6V6
Q40287
UFOG5_MANES
UDP-glucose flavonoid 3-O-glucosyltransferase 5
Manihot
<M><G><S><T><D><L><N><S><K><P><H><I><V><L><L><S><S><P><G><L><G><H><L><I><P><V><L><E><L><G><K><R><I><V><T><L><C><N><F><D><V><T><I><F><M><V><G><S><D><T><S><A><A><E><P><Q><V><L><R><S><A><M><T><P><K><L><C><E><I><I><Q><L><P><P><P><N><I><S><C><L><I><D><P><E><A><T><V><C><T><R><L><F><V><L><M><R><E><I><R><P><A><F><R><A><A><V><S...
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.<BOP>
Q40287
O74860
YQ9A_SCHPO
Putative pyridoxal kinase C18.10
Schizosaccharomyces
<M><T><F><P><N><V><K><F><I><G><N><K><R><V><L><S><I><Q><S><S><V><S><H><G><Y><V><G><N><R><S><A><T><F><P><L><Q><L><H><E><W><E><V><D><V><V><P><T><V><H><F><S><N><H><L><G><Y><G><A><T><R><G><S><A><C><I><P><E><E><V><H><D><L><L><N><A><L><L><Q><D><N><G><I><V><Y><D><A><I><L><T><G><F><V><P><N><H><D><I><I><Q><V><I><F><D><C><V><L><A...
Required for synthesis of pyridoxal-5-phosphate from vitamin B6.<BOP>
O74860
Q2L002
TSAD_BORA1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Bordetella
<M><I><I><L><G><F><E><S><S><C><D><E><T><G><V><A><A><V><C><T><Q><R><G><L><L><A><H><A><L><H><S><Q><I><A><M><H><Q><E><Y><G><G><V><V><P><E><L><A><S><R><D><H><I><R><R><I><V><P><L><T><R><E><V><L><A><Q><A><G><L><R><R><E><D><V><G><A><V><A><Y><T><A><G><P><G><L><A><G><A><L><L><V><G><A><S><V><A><Q><S><L><A><W><S><L><G><L><P><A><I...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q2L002
B0JNA9
URED_MICAN
Urease accessory protein UreD
Microcystis
<M><W><Q><G><N><L><E><L><I><Y><K><Q><K><N><L><A><T><E><I><N><H><V><Y><A><T><A><P><L><K><V><Q><R><P><F><Y><P><E><G><K><N><L><C><H><T><V><I><L><H><T><A><G><G><I><V><G><G><D><V><L><Q><Q><K><I><H><L><Q><A><A><T><N><A><L><I><T><T><A><S><A><G><K><V><Y><Q><S><N><G><Q><M><A><Q><Q><L><I><E><I><K><I><D><D><N><A><S><L><E><W><L><P...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
B0JNA9
Q9Z998
TAL_CHLPN
Transaldolase
Chlamydia
<M><S><N><Q><F><D><Q><L><K><K><L><S><T><I><V><C><D><S><G><D><P><E><L><V><K><A><S><G><S><Q><D><A><T><T><N><P><S><L><I><L><K><V><A><Q><E><P><K><F><Q><E><L><L><N><E><A><V><V><W><G><I><R><Q><N><G><D><D><L><Q><T><L><S><F><I><L><D><K><I><Q><V><N><F><A><L><E><I><I><K><N><I><P><G><R><I><S><L><E><I><D><A><R><L><S><F><N><V><E><A...
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP>
Q9Z998
Q9K5W7
TGL_HALH5
Transglutaminase
Halalkalibacterium (ex Joshi et al. 2022)
<M><G><N><D><M><I><Q><V><A><G><R><P><F><S><L><E><S><T><T><D><F><G><R><V><E><R><A><I><L><Q><Q><M><L><D><S><S><E><W><F><S><Y><S><S><M><N><E><L><R><F><E><L><N><V><R><I><N><I><M><E><S><A><K><E><M><N><A><S><Q><V><T><F><T><I><F><E><H><A><S><C><N><P><E><Y><W><T><L><T><S><T><G><G><F><L><V><R><S><D><V><R><P><S><D><A><I><L><D><I...
Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links.<BOP>
Q9K5W7
B7J5W3
YCIB_ACIF2
Inner membrane-spanning protein YciB
Acidithiobacillus
<M><K><L><L><T><D><F><L><P><I><I><L><F><F><V><A><Y><R><I><H><G><I><Y><T><A><T><E><V><L><I><V><A><A><I><L><L><M><A><W><Q><W><W><R><R><G><R><V><E><T><M><T><W><V><S><T><L><L><I><L><T><F><G><G><L><T><L><Y><F><H><N><D><T><F><I><K><I><K><P><S><I><L><Y><V><L><F><A><A><A><L><L><F><T><H><W><R><E><E><P><L><L><Q><R><L><M><G><G><Q...
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP>
B7J5W3
Q5GT66
TSAD_WOLTR
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
unclassified Wolbachia
<M><K><T><I><L><A><V><E><T><S><C><D><E><T><A><V><A><I><V><N><S><E><K><Q><V><L><A><Q><E><I><L><S><Q><T><E><H><K><K><R><G><G><V><I><P><E><I><A><S><R><A><H><M><E><H><L><S><S><L><I><K><N><S><I><E><K><S><N><L><N><F><C><N><L><D><A><T><A><A><T><S><G><P><G><L><I><G><G><L><I><V><G><T><M><M><A><K><A><I><A><H><V><T><Q><K><P><F><I...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q5GT66
Q0K020
TAUE_CUPNH
Probable sulfite/organosulfonate exporter TauE
Cupriavidus
<M><K><A><E><L><L><L><P><L><L><G><L><Q><A><L><L><G><A><G><T><Y><F><Q><T><V><T><G><F><G><L><G><M><I><V><M><G><V><T><S><G><L><G><L><A><P><V><A><T><V><A><A><V><V><S><L><V><T><L><A><N><S><A><C><A><L><P><G><K><L><Q><H><I><D><W><R><A><V><A><A><A><A><I><G><I><L><P><S><V><V><V><G><V><L><V><L><E><Y><L><S><S><S><A><A><T><L><L><Q...
Could be a sulfite/organosulfonate exporter with a wide substrate range, including 3-sulfolactate and 3-sulfopyruvate.<BOP>
Q0K020
Q18BF1
YQGF_CLOD6
Putative pre-16S rRNA nuclease
Clostridioides
<M><L><D><G><R><I><M><G><L><D><V><G><D><K><T><I><G><V><A><V><S><D><L><M><G><L><T><A><Q><G><V><K><T><I><K><R><V><G><K><K><K><D><I><E><E><L><K><A><I><I><K><E><K><Q><V><N><K><I><V><S><G><L><P><K><N><M><N><G><T><L><G><P><Q><G><E><K><V><I><K><F><C><E><L><V><K><A><E><T><G><I><D><V><E><F><W><D><E><R><L><S><T><V><A><A><E><R><S...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
Q18BF1
A8AK17
TIG_CITK8
PPIase
Citrobacter
<M><Q><V><S><V><E><T><T><Q><G><L><G><R><R><V><T><I><T><I><A><A><D><S><I><E><T><A><V><K><S><E><L><V><N><V><A><K><K><V><R><I><D><G><F><R><K><G><K><V><P><M><N><V><V><A><Q><R><Y><G><A><S><V><R><Q><D><V><L><G><D><L><M><S><R><N><F><V><D><A><I><I><K><E><K><I><N><P><A><G><A><P><N><Y><V><P><G><E><Y><K><L><G><E><D><F><T><Y><A><V...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A8AK17
B9MFI6
UPPP_ACIET
Undecaprenyl pyrophosphate phosphatase
Diaphorobacter
<M><D><T><L><L><L><L><K><A><A><I><M><G><V><V><E><G><L><T><E><F><L><P><I><S><S><T><G><H><L><I><L><A><G><S><L><L><G><F><D><D><A><K><A><K><V><F><D><I><A><I><Q><T><G><A><I><F><A><V><I><L><V><Y><W><Q><R><I><R><A><T><L><V><A><L><P><T><E><R><Q><A><R><R><F><A><L><N><V><L><I><G><F><L><P><A><V><L><L><G><L><L><L><G><K><A><I><K><A...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
B9MFI6
Q2TBH5
UBXN8_BOVIN
UBX domain-containing protein 6
Bos
<M><A><S><R><G><V><V><G><I><F><L><L><S><A><L><P><L><L><C><L><E><L><R><R><G><K><P><D><L><G><I><K><D><L><I><L><L><C><G><R><I><F><L><L><L><A><L><L><T><L><I><I><S><V><T><T><S><W><V><N><S><F><K><P><S><Q><V><Y><L><K><E><E><E><E><K><N><E><K><R><Q><K><L><V><R><K><K><Q><Q><E><A><Q><G><E><K><V><S><R><Y><I><E><N><V><L><K><P><S><Q...
May play a role in reproduction.<BOP>
Q2TBH5
B8CLM6
TRPB_SHEPW
Tryptophan synthase beta chain
Shewanella
<M><S><K><L><N><P><Y><F><G><E><Y><G><G><M><Y><V><P><Q><I><L><M><P><A><L><K><Q><L><E><T><A><F><I><E><A><Q><Q><D><E><A><F><Q><K><E><F><T><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><L><T><R><N><L><S><P><N><P><L><A><K><I><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><K><E><I><I><A...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
B8CLM6
Q6MTI1
TRMD_MYCMS
tRNA [GM37] methyltransferase
Mycoplasma
<M><K><F><S><I><I><T><L><F><P><K><I><I><N><S><Y><I><E><E><S><I><I><K><R><A><I><N><K><Q><A><I><K><I><E><I><I><D><L><R><N><F><S><T><L><S><H><N><Q><V><D><D><Y><Q><Y><G><G><G><S><G><M><V><L><M><I><E><P><L><I><K><A><I><E><S><V><K><T><T><K><S><I><V><L><L><T><T><P><Q><G><K><T><L><N><Q><S><I><V><K><T><Y><A><N><N><Y><E><H><I><I...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q6MTI1
Q45557
TRUA_BACSV
tRNA-uridine isomerase I
Bacillus
<M><N><N><Y><K><L><M><I><Q><Y><D><G><G><R><Y><K><G><W><Q><R><L><G><N><G><E><N><T><I><Q><G><K><I><E><T><V><L><S><E><M><V><G><R><K><I><E><I><I><G><S><G><R><T><D><A><G><V><H><A><L><G><Q><V><A><N><V><K><L><S><E><N><F><T><V><K><E><V><K><E><Y><L><N><R><Y><L><P><H><D><I><S><V><T><E><V><T><L><V><P><D><R><F><H><S><R><Y><N><A><K...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
Q45557
A1A1Q5
TSAD_BIFAA
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Bifidobacterium
<M><S><E><P><I><V><L><G><I><E><S><T><C><D><E><T><A><A><A><V><V><Q><G><R><T><L><I><S><N><V><V><A><S><S><M><D><E><H><A><R><Y><G><G><V><I><P><E><I><A><S><R><A><H><A><E><A><F><V><P><C><V><S><K><A><L><A><D><A><N><M><T><L><S><D><V><D><A><I><A><V><S><A><G><P><G><L><A><G><C><L><A><V><G><V><S><G><A><K><S><L><A><W><A><A><N><K><P...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
A1A1Q5
Q04235
TYW2_YEAST
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase
Saccharomyces
<M><S><D><E><T><M><P><V><E><F><L><V><S><D><K><R><L><L><K><T><I><K><V><K><L><E><T><N><G><L><F><V><T><P><I><Y><S><D><N><D><N><K><V><I><K><S><S><I><E><D><L><N><H><P><L><A><V><E><I><N><N><I><A><G><V><K><A><R><F><H><E><S><G><N><L><E><R><S><E><G><H><L><K><H><Q><S><N><S><I><T><E><F><T><K><S><F><L><K><D><H><G><L><A><N><D><K><I...
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl...
Q04235
P30961
YCIB_BRADU
Inner membrane-spanning protein YciB
Bradyrhizobium
<M><D><K><T><Q><P><H><P><L><F><K><L><A><T><E><L><G><P><L><L><V><F><F><F><V><N><A><K><F><N><L><F><A><A><T><G><A><F><M><V><A><I><V><A><A><M><I><A><S><Y><V><V><T><R><H><I><P><I><M><A><I><V><T><G><V><I><V><L><V><F><G><T><L><T><L><V><L><H><D><E><T><F><I><K><V><K><P><T><I><I><Y><G><L><F><A><A><I><L><G><G><G><L><L><F><G><R><S...
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP>
P30961
Q8ES61
Y782_OCEIH
Putative metal-dependent hydrolase OB0782
Oceanobacillus
<M><N><E><K><Y><P><I><G><E><F><Q><F><D><G><E><I><T><N><I><I><I><N><E><W><I><N><E><I><E><D><L><P><R><L><L><K><N><T><V><I><D><L><N><N><E><Q><L><D><T><S><Y><R><S><G><G><W><T><V><R><Q><V><I><H><H><L><A><D><S><H><M><N><A><Y><I><R><L><K><L><A><I><T><E><E><N><P><V><I><K><P><Y><D><E><K><E><W><A><E><L><Y><D><Y><N><L><P><I><E><I...
Possible metal-dependent hydrolase.<BOP>
Q8ES61
B4L1K2
UBA5_DROMO
Ubiquitin-like modifier-activating enzyme 5
Drosophila
<M><S><T><A><I><D><E><L><Q><A><I><I><A><E><L><K><T><E><L><E><E><Q><K><T><S><T><R><I><A><R><E><R><I><E><R><M><S><A><E><V><V><D><S><N><P><Y><S><R><L><M><A><L><Q><R><M><N><I><V><K><D><Y><E><R><I><R><D><K><A><V><A><I><V><G><V><G><G><V><G><S><V><T><A><D><M><L><T><R><C><G><I><G><K><L><I><L><F><D><Y><D><K><V><E><L><A><N><M><N...
E1-like enzyme which activates UFM1.<BOP>
B4L1K2
A7MEN2
XGPT_CROS8
Xanthine phosphoribosyltransferase
Cronobacter
<M><S><E><K><Y><V><V><T><W><D><M><L><Q><I><H><A><R><K><L><A><S><R><L><L><P><A><E><Q><W><K><G><I><I><A><V><S><R><G><G><L><V><P><G><A><L><L><A><R><E><L><G><I><R><H><V><D><T><V><C><I><S><S><Y><D><H><D><N><Q><R><E><L><K><V><I><K><R><A><E><G><D><G><E><G><F><I><V><V><D><D><L><V><D><T><G><G><T><A><V><A><I><R><E><M><Y><P><K><A...
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with...
A7MEN2
A0JRH6
UREF_ARTS2
Urease accessory protein UreF
Arthrobacter
<M><A><A><A><G><S><Y><Q><L><A><L><Q><Q><L><T><D><S><A><L><P><T><G><A><F><A><H><S><L><G><F><E><T><Y><I><E><R><G><L><V><H><D><E><A><S><F><G><V><W><L><S><A><F><V><G><Q><Q><L><S><Y><S><D><G><L><A><I><R><F><L><Y><E><G><V><S><F><A><E><L><D><A><L><L><T><A><Q><L><L><P><R><Q><L><R><E><A><S><T><K><M><G><T><R><L><L><E><I><G><T><E...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
A0JRH6
Q55624
Y755_SYNY3
Thioredoxin reductase
unclassified Synechocystis
<M><T><E><V><L><R><V><G><Q><P><A><P><D><F><T><A><T><A><I><V><D><Q><S><F><Q><T><V><K><L><S><T><Y><R><G><K><Y><L><V><L><F><F><Y><P><L><D><F><T><F><V><C><P><T><E><I><I><A><F><S><D><R><H><S><E><F><T><A><L><D><T><E><V><V><G><I><S><V><D><S><E><F><S><H><L><A><W><I><Q><T><E><R><K><M><G><G><I><G><N><I><N><Y><P><L><V><S><D><L><K...
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP>
Q55624
P0AED5
UVRY_ECOLI
Response regulator UvrY
Escherichia
<M><I><N><V><L><L><V><D><D><H><E><L><V><R><A><G><I><R><R><I><L><E><D><I><K><G><I><K><V><V><G><E><A><S><C><G><E><D><A><V><K><W><C><R><T><N><A><V><D><V><V><L><M><D><M><S><M><P><G><I><G><G><L><E><A><T><R><K><I><A><R><S><T><A><D><V><K><I><I><M><L><T><V><H><T><E><N><P><L><P><A><K><V><M><Q><A><G><A><A><G><Y><L><S><K><G><A><A...
Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system . UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independ...
P0AED5