accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
P26921
TRPB2_METTM
Tryptophan synthase beta chain 2
Methanothermobacter
<M><D><G><K><F><G><K><Y><G><G><I><F><V><P><E><L><L><I><P><A><L><E><E><L><E><A><A><F><L><H><Y><S><K><D><R><R><F><N><E><D><L><E><H><Y><L><R><E><Y><A><G><R><P><T><G><L><Y><H><A><R><N><L><S><E><K><L><G><C><R><V><Y><L><K><R><E><D><M><L><H><T><G><A><H><K><I><N><N><T><I><G><Q><A><L><L><A><G><Y><M><G><K><R><R><L><I><A><E><T><G...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
P26921
Q9PN51
UVRC_CAMJE
Excinuclease ABC subunit C
Campylobacter
<M><T><K><E><N><L><E><N><E><L><K><T><L><P><N><S><T><G><V><Y><Q><Y><F><N><Q><E><G><K><L><L><Y><V><G><K><A><K><N><L><K><N><R><V><R><S><Y><F><A><F><T><P><N><L><H><A><N><P><R><N><S><L><R><I><Q><K><M><I><E><E><T><V><H><L><E><F><I><A><T><N><S><E><A><D><A><L><I><L><E><N><S><F><I><K><Q><L><H><P><K><Y><N><I><L><L><R><D><D><K><T...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q9PN51
Q59674
XY11A_CELJA
Acetylxylan deacetylase
Cellvibrio
<M><K><L><P><T><L><G><K><C><V><V><R><T><L><M><G><A><V><A><L><G><A><I><S><V><N><A><Q><T><L><S><S><N><S><T><G><T><N><N><G><F><Y><Y><T><F><W><K><D><S><G><D><A><S><M><T><L><L><S><G><G><R><Y><Q><S><S><W><G><N><S><T><N><N><W><V><G><G><K><G><W><N><P><G><N><N><S><R><V><I><S><Y><S><G><S><Y><G><V><D><S><S><Q><N><S><Y><L><A><L><Y...
Endo-acting xylanase which specifically cleaves internal linkages on the xylan backbone, releasing xylooligosaccharides. Is able to hydrolyze oat spelt xylan and the arabinoxylans from wheat and rye, releasing xylobiose as the major product. Also likely catalyzes, via its C-terminal domain, the removal of acetyl groups...
Q59674
B6EGG3
XNI_ALISL
Flap endonuclease Xni
Aliivibrio
<M><A><I><H><L><V><I><I><D><A><L><N><L><I><R><R><V><H><S><A><Q><P><N><Q><D><D><I><Q><A><V><V><T><T><T><G><R><T><I><N><R><I><L><K><E><T><E><P><T><H><I><I><A><V><F><D><H><H><L><Q><D><R><G><W><R><A><E><V><L><P><K><Y><K><E><D><R><K><P><M><P><E><A><L><Q><K><G><M><D><A><I><Q><E><S><W><W><K><L><G><I><D><S><L><L><S><D><G><D><E...
Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.<BOP>
B6EGG3
P13726
TF_HUMAN
Thromboplastin
Homo
<M><E><T><P><A><W><P><R><V><P><R><P><E><T><A><V><A><R><T><L><L><L><G><W><V><F><A><Q><V><A><G><A><S><G><T><T><N><T><V><A><A><Y><N><L><T><W><K><S><T><N><F><K><T><I><L><E><W><E><P><K><P><V><N><Q><V><Y><T><V><Q><I><S><T><K><S><G><D><W><K><S><K><C><F><Y><T><T><D><T><E><C><D><L><T><D><E><I><V><K><D><V><K><Q><T><Y><L><A><R><V...
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<BOP>
P13726
Q925D8
TS1R3_MOUSE
Sweet taste receptor T1R3
Mus
<M><P><A><L><A><I><M><G><L><S><L><A><A><F><L><E><L><G><M><G><A><S><L><C><L><S><Q><Q><F><K><A><Q><G><D><Y><I><L><G><G><L><F><P><L><G><S><T><E><E><A><T><L><N><Q><R><T><Q><P><N><S><I><P><C><N><R><F><S><P><L><G><L><F><L><A><M><A><M><K><M><A><V><E><E><I><N><N><G><S><A><L><L><P><G><L><R><L><G><Y><D><L><F><D><T><C><S><E><P><V...
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition...
Q925D8
B8CLE4
TOLB_SHEPW
Tol-Pal system protein TolB
Shewanella
<M><K><I><L><G><K><W><L><L><A><S><L><L><I><C><S><M><P><A><K><A><A><L><D><I><V><I><T><E><G><V><D><A><A><R><P><I><A><V><V><P><F><V><W><Q><G><T><G><P><M><P><S><Q><I><S><D><V><V><M><S><D><L><A><R><S><G><T><F><S><P><S><D><E><L><S><L><P><Q><R><N><I><S><T><L><A><Q><F><D><A><K><A><W><M><A><Q><P><A><E><A><V><V><M><G><S><I><K><P...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
B8CLE4
Q6ZRF7
ZN818_HUMAN
Putative zinc finger protein 818
Homo
<M><L><E><R><N><L><T><S><M><M><S><V><E><E><P><L><P><R><P><L><T><S><L><Y><I><R><L><S><I><L><E><R><N><H><M><N><M><T><Y><M><A><K><S><S><V><K><I><H><I><S><K><V><I><I><G><F><V><L><K><R><S><L><T><N><V><C><G><K><V><L><S><Q><N><S><H><L><V><N><H><Q><R><I><H><T><G><E><K><S><Y><R><C><H><E><C><G><K><A><F><T><Q><G><S><R><F><I><N><H...
May be involved in transcriptional regulation.<BOP>
Q6ZRF7
B2U928
TSAD_RALPJ
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Ralstonia
<M><L><V><L><G><I><E><S><S><C><D><E><T><G><V><A><L><Y><D><T><H><S><G><L><R><A><H><A><L><Y><S><Q><I><A><M><H><R><E><Y><G><G><V><V><P><E><L><A><S><R><D><H><I><R><R><V><I><P><L><L><E><E><V><L><G><K><A><G><A><T><R><A><D><I><D><A><I><A><Y><T><K><G><P><G><L><A><G><A><L><L><V><G><A><S><V><A><N><A><L><A><F><A><L><G><K><P><L><V...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
B2U928
Q8IWB9
TEX2_HUMAN
Transmembrane protein 96
Homo
<M><T><S><L><Y><G><R><H><A><E><K><T><T><D><M><P><K><P><S><A><P><K><V><H><V><Q><R><S><V><S><R><D><T><I><A><I><H><F><S><A><S><G><E><E><E><E><E><E><E><E><E><F><R><E><Y><F><E><E><G><L><D><D><Q><S><I><V><T><G><L><E><A><K><E><D><L><Y><L><E><P><Q><V><G><H><D><P><A><G><P><A><A><S><P><V><L><A><D><G><L><S><V><S><Q><A><P><A><I><L...
During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, may induce contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation.<B...
Q8IWB9
Q62HU9
UBID_BURMA
Polyprenyl p-hydroxybenzoate decarboxylase
pseudomallei group
<M><K><Y><R><D><L><R><D><F><I><H><G><L><E><Q><R><G><E><L><R><R><V><T><Q><P><V><S><P><V><L><E><M><T><E><L><C><D><R><V><L><R><A><G><G><P><A><L><L><F><D><A><P><A><G><H><R><F><P><V><L><G><N><L><F><G><T><P><R><R><V><A><L><G><M><G><V><D><A><D><D><E><A><A><L><A><S><L><R><D><I><G><R><L><L><S><A><L><K><E><P><D><P><P><K><R><L><K...
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP>
Q62HU9
B9E8X3
Y1934_MACCJ
Nucleoid-associated protein MCCL_1934
Macrococcus
<M><R><G><G><G><N><M><Q><Q><M><M><K><Q><M><Q><K><M><Q><K><K><M><A><E><E><Q><E><K><L><K><E><E><R><I><E><G><T><A><G><G><G><M><V><T><V><V><V><S><G><H><K><E><V><L><D><V><I><I><K><E><E><V><V><D><P><E><D><I><E><M><L><Q><D><L><V><L><A><A><T><N><D><A><L><T><K><A><D><D><V><T><A><Q><R><L><G><Q><H><T><K><G><L><N><I><P><G><M><M>
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
B9E8X3
O08712
TR11B_MOUSE
Osteoprotegerin
Mus
<M><N><K><W><L><C><C><A><L><L><V><L><L><D><I><I><E><W><T><T><Q><E><T><L><P><P><K><Y><L><H><Y><D><P><E><T><G><H><Q><L><L><C><D><K><C><A><P><G><T><Y><L><K><Q><H><C><T><V><R><R><K><T><L><C><V><P><C><P><D><H><S><Y><T><D><S><W><H><T><S><D><E><C><V><Y><C><S><P><V><C><K><E><L><Q><S><V><K><Q><E><C><N><R><T><H><N><R><V><C><E><C...
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcifica...
O08712
A1S7I2
TRPB_SHEAM
Tryptophan synthase beta chain
Shewanella
<M><S><E><L><K><L><D><P><Y><F><G><E><Y><G><G><M><Y><V><P><Q><I><L><M><P><A><L><K><Q><L><E><T><A><F><V><E><A><Q><Q><D><P><E><F><L><T><E><F><H><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><L><T><R><N><L><S><P><N><P><K><V><K><I><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><K><E><I...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
A1S7I2
B8CKH5
TRUB_SHEPW
tRNA-uridine isomerase
Shewanella
<M><A><R><R><S><R><G><R><H><I><D><G><V><L><L><L><D><K><D><T><G><M><S><S><N><F><A><L><Q><R><V><K><R><F><F><N><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><H><L><L><D><A><D><K><R><Y><L><V><T><A><K><L><G><Q><R><T><D><T><S><D><S><D><G><E><V><V><Q><T><R><E><I><D><F><T><Q><E><Q><L...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
B8CKH5
Q8MKD1
UBB_HORSE
Ubiquitin-related
Equus
<M><Q><I><F><V><K><T><L><T><G><K><T><I><T><L><E><V><E><P><S><D><T><I><E><N><V><K><A><K><I><Q><D><K><E><G><I><P><P><D><Q><Q><R><L><I><F><A><G><K><Q><L><E><D><G><R><T><L><S><D><Y><N><I><Q><K><E><S><T><L><H><L><V><L><R><L><R><G><G><M><Q><I><F><V><K><T><L><T><G><K><T><I><T><L><E><V><E><P><S><D><T><I><E><N><V><K><A><K><I><Q...
Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initia...
Q8MKD1
Q8KEJ1
THIG_CHLTE
Thiazole synthase
Chlorobaculum
<M><D><S><L><R><L><G><T><Y><T><F><S><S><R><L><I><L><G><T><G><K><F><S><S><T><S><A><M><I><K><A><V><R><A><S><G><T><Q><L><V><T><V><A><L><R><R><F><N><R><E><Q><A><E><D><D><L><F><G><P><L><S><E><I><E><G><L><T><L><M><P><N><T><S><G><A><A><T><A><K><E><A><I><K><A><A><H><I><A><R><E><L><S><G><S><P><F><I><K><V><E><I><H><P><N><P><H><H...
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP>
Q8KEJ1
A4Y845
TRPB_SHEPC
Tryptophan synthase beta chain
Shewanella
<M><S><T><L><K><L><N><P><Y><F><G><E><Y><G><G><M><Y><V><P><Q><I><L><V><P><A><L><K><Q><L><E><T><A><F><V><E><A><Q><E><D><E><D><F><K><A><E><F><T><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><L><T><R><N><L><S><P><N><P><M><V><K><I><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><K><E><I...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
A4Y845
B8EA59
THIG_SHEB2
Thiazole synthase
Shewanella
<M><L><T><I><A><D><V><E><F><E><S><R><L><F><T><G><T><G><K><F><S><N><S><Q><V><M><L><E><A><I><T><A><S><K><S><Q><L><V><T><V><A><M><K><R><I><D><F><K><M><G><L><D><D><L><L><T><P><L><R><Q><A><G><V><R><L><L><P><N><T><S><G><A><R><N><A><K><E><A><V><F><A><A><E><L><A><R><E><M><L><G><T><H><W><I><K><L><E><I><H><P><D><P><K><Y><L><M><P...
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP>
B8EA59
A0PJN4
U2QL1_MOUSE
E2Q-like ubiquitin-conjugating enzyme 1
Mus
<M><K><E><L><Q><D><I><A><R><L><S><D><R><F><I><S><V><E><L><V><N><E><N><L><F><D><W><N><V><K><L><H><Q><V><D><K><D><S><V><L><W><Q><D><M><K><E><T><N><T><E><F><I><L><L><N><L><T><F><P><D><N><F><P><F><S><P><P><F><M><R><V><L><S><P><R><L><E><N><G><Y><V><L><D><G><G><A><I><C><M><E><L><L><T><P><R><G><W><S><S><A><Y><T><V><E><A><V><M...
Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7.<BOP>
A0PJN4
Q329B2
YIDC_SHIDS
Membrane protein YidC
Shigella
<M><D><S><Q><R><N><L><L><V><I><A><L><L><F><V><S><F><M><I><W><Q><A><W><E><Q><D><K><N><P><Q><P><Q><A><Q><Q><T><T><Q><T><T><T><T><A><A><G><S><A><A><D><Q><G><V><P><A><S><G><Q><G><K><L><I><S><V><K><T><D><V><L><D><L><T><I><N><T><R><G><G><D><V><E><Q><A><L><L><P><A><Y><P><K><E><L><N><S><T><Q><P><F><Q><L><L><E><T><S><P><Q><F><I...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb...
Q329B2
P40200
TACT_HUMAN
T cell-activated increased late expression protein
Homo
<M><E><K><K><W><K><Y><C><A><V><Y><Y><I><I><Q><I><H><F><V><K><G><V><W><E><K><T><V><N><T><E><E><N><V><Y><A><T><L><G><S><D><V><N><L><T><C><Q><T><Q><T><V><G><F><F><V><Q><M><Q><W><S><K><V><T><N><K><I><D><L><I><A><V><Y><H><P><Q><Y><G><F><Y><C><A><Y><G><R><P><C><E><S><L><V><T><F><T><E><T><P><E><N><G><S><K><W><T><L><H><L><R><N...
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are ac...
P40200
Q2KP58
UQCC3_XENLA
Oocyte antigen VAP18
Xenopus
<M><E><T><V><R><R><I><V><K><G><T><L><L><L><G><F><C><T><G><I><G><G><D><L><W><V><L><V><A><P><G><Q><E><R><R><L><E><M><R><M><N><Y><P><E><A><N><P><P><M><L><A><E><A><H><K><R><N><E><M><V><L><K><V><I><E><E><S><A><K><T><N><E><N><M><A><R><R><S><P><W><S><S>
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding pr...
Q2KP58
A4G8J0
UPPP_HERAR
Undecaprenyl pyrophosphate phosphatase
Herminiimonas
<M><D><T><I><L><A><L><K><V><I><I><M><G><I><V><E><G><L><T><E><F><L><P><I><S><S><T><G><H><L><I><L><A><G><S><L><L><E><F><T><G><P><K><V><K><V><F><E><I><A><I><Q><T><G><A><M><L><A><V><V><W><E><Y><R><V><K><I><A><A><V><L><G><G><L><F><T><E><R><R><A><Q><K><F><A><V><N><I><V><V><A><F><L><P><A><A><L><L><G><L><V><F><A><G><A><I><K><E...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
A4G8J0
A7MMG1
TRPB_CROS8
Tryptophan synthase beta chain
Cronobacter
<M><S><T><L><L><N><P><Y><F><G><E><F><G><G><M><Y><V><P><Q><I><L><M><P><A><L><R><Q><L><E><E><A><F><V><S><A><Q><S><D><A><E><F><Q><A><Q><F><T><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><K><C><Q><N><L><T><E><G><T><R><T><T><L><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><T><E><I><I...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
A7MMG1
Q8CR47
XYLB_STAES
Xylulose kinase
Staphylococcus
<M><V><K><E><V><V><L><G><I><D><L><G><T><S><A><I><K><I><I><A><V><D><Q><L><G><N><V><I><E><S><V><S><E><T><L><K><L><Y><Q><E><H><P><G><Y><S><E><Q><D><P><N><E><W><F><E><A><T><K><K><G><I><K><E><L><I><Q><S><T><E><M><S><D><K><I><V><K><G><I><S><F><S><G><Q><M><H><G><L><V><I><V><D><D><N><G><I><P><L><R><K><A><I><L><W><N><D><T><R><N...
Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.<BOP>
Q8CR47
B5YDB8
UPP_DICT6
UPRTase
Dictyoglomus
<M><V><I><V><V><D><H><P><L><V><Q><H><K><L><T><K><L><R><D><K><N><T><G><P><K><E><F><R><E><L><L><F><E><I><S><S><L><M><L><Y><E><V><T><K><N><L><P><T><K><E><V><E><V><E><T><P><L><G><I><A><K><G><K><V><L><D><N><K><D><L><A><I><V><P><I><L><R><A><G><L><V><M><A><D><G><M><L><Q><I><L><P><S><A><K><V><G><H><I><G><L><Y><R><D><P><E><T><L...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
B5YDB8
O13489
TRI5_PARRD
Sesquiterpene cyclase
Paramyrothecium
<M><D><E><F><P><T><E><Y><F><L><G><T><A><V><R><L><L><E><N><V><K><Y><R><D><S><N><Y><T><R><E><E><R><I><E><N><L><S><Y><A><N><N><K><A><A><A><H><F><A><Q><E><R><Q><Q><R><I><L><K><V><N><P><K><R><L><E><A><S><L><R><T><I><V><G><M><V><V><Y><S><W><V><K><V><S><K><E><L><M><A><D><L><S><I><H><Y><T><Y><T><L><I><L><D><D><S><E><D><D><P><H...
TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.<BOP>
O13489
P42883
THI12_YEAST
Thiamine pyrimidine synthase
Saccharomyces
<M><S><T><D><K><I><T><F><L><L><N><W><Q><P><T><P><Y><H><I><P><I><F><L><A><Q><T><K><G><Y><F><K><E><Q><G><L><D><M><A><I><L><E><P><T><N><P><S><D><V><T><E><L><I><G><S><G><K><V><D><M><G><L><K><A><M><I><H><T><L><A><A><K><A><R><G><F><P><V><T><S><V><A><S><L><L><D><E><P><F><T><G><V><L><Y><L><K><G><S><G><I><T><E><D><F><Q><S><L><K...
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme...
P42883
Q9VYY3
UBA5_DROME
UFM1-activating enzyme
Sophophora
<M><S><H><A><I><D><E><L><Q><A><I><I><A><D><L><K><T><E><L><E><T><E><P><K><S><S><G><G><V><A><S><N><S><R><L><A><R><D><R><I><D><R><M><S><A><E><V><V><D><S><N><P><Y><S><R><L><M><A><L><Q><R><M><N><I><V><K><D><Y><E><R><I><R><Y><K><A><V><A><I><V><G><V><G><G><V><G><S><V><T><A><D><M><L><T><R><C><G><I><G><K><L><I><L><F><D><Y><D><K...
E1-like enzyme which activates UFM1.<BOP>
Q9VYY3
Q491Y3
TPIS_BLOPB
Triose-phosphate isomerase
Candidatus Blochmannia
<M><R><R><L><L><I><I><G><N><W><K><L><N><G><N><K><N><T><I><T><N><L><I><I><T><L><V><N><T><F><Y><N><I><S><K><C><N><V><A><I><A><P><P><V><M><Y><L><D><I><T><K><R><Y><L><L><N><S><R><I><Q><L><C><A><Q><N><V><D><I><H><L><S><G><S><F><T><G><D><I><S><A><E><M><L><Q><D><L><N><V><R><Y><A><L><I><G><H><S><E><R><R><I><H><H><K><E><N><D><A...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
Q491Y3
A1VYG9
THIC_CAMJJ
Thiamine biosynthesis protein ThiC
Campylobacter
<M><K><T><Q><M><N><Y><A><K><E><G><I><F><T><K><E><M><Q><I><V><A><Q><K><E><N><L><S><K><D><F><L><L><E><N><I><A><C><G><K><I><I><I><P><A><N><I><N><H><K><S><L><D><P><N><G><I><G><F><G><L><R><T><K><V><N><V><N><L><G><V><S><N><D><C><V><D><Y><S><E><E><M><K><K><V><E><L><A><H><K><F><G><I><E><A><I><M><D><L><S><N><Y><G><K><T><S><R><F...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
A1VYG9
B2SIG7
TTCA_XANOP
tRNA 2-thiocytidine biosynthesis protein TtcA
Xanthomonas
<M><T><A><V><L><P><L><P><H><P><L><A><D><P><A><P><R><D><P><R><Q><R><L><Q><R><E><Q><L><R><L><G><K><R><L><Q><R><Q><V><G><Q><A><I><A><D><F><G><M><I><S><P><G><D><K><I><M><V><C><L><S><G><G><K><D><S><Y><T><M><L><D><M><L><L><Q><L><Q><R><K><A><P><V><P><F><T><L><V><A><V><N><L><D><Q><K><Q><P><D><F><P><A><H><V><L><P><A><Y><L><D><A...
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP>
B2SIG7
Q6GJQ9
XPT_STAAR
Xanthine phosphoribosyltransferase
Staphylococcus
<M><E><L><L><G><Q><K><V><K><E><D><G><V><V><I><D><E><R><I><L><K><V><D><G><F><L><N><H><Q><I><D><A><K><L><M><D><E><V><G><R><T><F><Y><E><Q><F><K><D><K><G><I><T><K><I><L><T><I><E><A><S><G><I><A><P><A><I><M><A><A><L><H><F><D><V><P><C><L><F><A><K><K><A><K><P><S><T><L><T><D><G><Y><Y><E><T><S><I><H><S><F><T><K><N><K><T><S><T><V...
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP>
Q6GJQ9
B9KNX7
TRMD_CERSK
tRNA [GM37] methyltransferase
Cereibacter
<M><L><K><G><A><W><Q><A><R><I><V><T><L><F><P><E><A><F><P><G><T><L><G><L><S><L><T><G><K><A><L><E><M><G><L><W><S><L><E><T><I><D><L><R><P><F><G><E><G><R><H><R><N><V><D><D><N><P><A><G><G><G><A><G><M><V><L><R><A><D><I><V><A><R><A><L><D><A><A><S><V><G><T><P><S><E><R><S><R><W><P><V><V><Y><L><S><P><R><G><K><P><F><S><Q><A><M><A...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
B9KNX7
P75291
ULAA_MYCPN
Ascorbate-specific permease IIC component UlaA
Mycoplasma
<M><L><N><K><I><K><L><Q><Q><K><R><K><L><I><I><G><W><S><V><F><A><L><I><N><L><V><V><I><L><L><T><V><L><L><R><A><G><L><P><N><L><V><S><K><G><V><T><P><F><S><A><Q><A><F><G><D><A><F><I><F><L><I><T><R><V><Y><L><D><N><F><L><R><Q><P><A><L><L><L><G><V><I><T><L><I><G><Y><L><A><L><G><R><G><G><V><Q><S><V><V><G><A><L><K><T><V><I><G><F...
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP...
P75291
G3Y422
YAND_ASPNA
Yanuthone D biosynthesis cluster protein D
Aspergillus subgen. Circumdati
<M><V><K><F><F><Q><P><K><I><D><P><L><P><T><G><I><D><L><T><G><K><T><A><V><I><T><G><A><S><A><G><M><G><L><E><V><T><K><Q><L><L><R><L><R><L><S><T><A><I><L><A><V><R><N><V><T><K><G><E><A><C><I><K><S><L><L><Q><D><R><G><I><Q><T><H><N><P><K><P><T><I><K><V><M><E><L><D><M><D><R><Y><D><S><V><Q><Q><F><A><K><T><L><R><E><E><V><P><V><V...
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of yanuthone D, a fungal isoprenoid epoxycyclohexenone that acts as an antibiotic against fungi and bacteria . The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase yanA . 6-MSA is th...
G3Y422
B2U0F2
TRPB_SHIB3
Tryptophan synthase beta chain
Shigella
<M><T><T><L><L><N><P><Y><F><G><E><F><G><G><M><Y><V><P><Q><I><L><M><P><A><L><R><Q><L><E><E><A><F><V><S><A><Q><K><D><P><E><F><Q><A><Q><F><N><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><K><C><Q><N><I><T><A><G><T><N><T><T><L><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><T><E><I><I...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
B2U0F2
Q96NJ3
ZN285_HUMAN
Zinc finger protein 285A
Homo
<M><I><K><F><Q><E><R><V><T><F><K><D><V><A><V><V><F><T><K><E><E><L><A><L><L><D><K><A><Q><I><N><L><Y><Q><D><V><M><L><E><N><F><R><N><L><M><L><V><R><D><G><I><K><N><N><I><L><N><L><Q><A><K><G><L><S><Y><L><S><Q><E><V><L><H><C><W><Q><I><W><K><Q><R><I><R><D><L><T><V><S><Q><D><Y><I><V><N><L><Q><E><E><C><S><P><H><L><E><D><V><S><L...
May be involved in transcriptional regulation.<BOP>
Q96NJ3
A4VZL1
TRHO_STRS2
tRNA hydroxylation protein O
Streptococcus
<M><S><K><D><I><R><V><L><L><Y><Y><K><Y><V><P><I><E><N><A><K><E><Y><A><A><E><H><L><A><F><C><K><S><I><G><L><K><G><R><I><L><I><A><D><E><G><I><N><G><T><V><S><G><D><Y><E><T><T><Q><K><Y><M><D><Y><V><H><A><N><P><L><F><S><D><L><W><F><K><I><D><E><E><N><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><D><F><D...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
A4VZL1
Q54F34
Y1141_DICDI
Probable zinc transporter protein DDB_G0291141
Dictyostelium
<M><A><G><S><L><D><D><S><I><Y><N><N><G><R><S><G><G><G><G><G><G><F><K><F><S><K><G><F><N><K><D><S><I><S><K><R><I><I><M><M><L><F><F><S><K><G><I><R><A><W><S><C><I><I><L><L><Y><F><L><Q><S><S><I><S><I><I><S><A><S><F><Y><M><C><L><F><S><A><I><F><S><V><V><V><E><K><P><W><N><L><L><S><S><L><R><P><S><Q><I><K><K><I><I><Y><H><S><I><F...
May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces.<BOP>
Q54F34
Q04BH0
TPIS_LACDB
Triose-phosphate isomerase
Lactobacillus
<M><S><R><T><P><I><I><A><G><N><W><K><L><N><M><N><P><K><E><T><V><E><F><V><N><A><V><K><D><Q><L><P><D><P><S><K><V><E><S><V><I><C><A><P><A><V><D><L><D><A><L><L><K><A><A><E><G><S><N><L><H><V><G><A><E><N><C><Y><W><E><N><S><G><A><F><T><G><E><T><S><P><A><V><L><K><E><M><G><V><Q><Y><V><I><I><G><H><S><E><R><R><D><Y><F><H><E><T><D...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
Q04BH0
P59783
YIDC_SHIFL
Membrane protein YidC
Shigella
<M><D><S><Q><R><N><L><L><V><I><A><L><L><F><V><S><F><M><I><W><Q><A><W><E><Q><D><K><N><P><Q><P><Q><A><Q><Q><T><T><Q><T><T><T><T><A><A><G><S><A><A><D><Q><G><V><P><A><S><G><Q><G><K><L><I><S><V><K><T><D><V><L><D><L><T><I><N><T><R><G><G><D><V><E><Q><A><L><L><P><A><Y><P><K><E><L><N><S><T><Q><P><F><Q><L><L><E><T><S><P><Q><F><I...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb...
P59783
Q98Q98
TRMD_MYCPU
tRNA [GM37] methyltransferase
Mycoplasmopsis
<M><L><K><I><N><F><L><T><I><F><P><K><Y><F><D><C><F><L><K><E><S><I><I><G><K><A><I><E><R><K><K><I><S><I><N><V><I><D><F><R><E><F><S><E><N><K><H><K><K><V><D><D><S><V><Y><G><G><G><Q><G><M><L><L><Q><V><Q><P><I><A><K><A><L><K><T><L><K><G><L><K><I><L><V><S><P><Q><G><K><L><F><N><Q><E><I><A><K><E><I><V><K><N><H><S><E><I><T><F><V...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q98Q98
Q7VPM2
YIDC_HAEDU
Membrane protein YidC
Haemophilus
<M><N><S><N><R><S><L><L><V><M><G><L><L><L><V><S><F><L><I><F><T><Q><W><Q><Q><D><F><N><P><E><I><Q><A><Q><K><Q><A><Q><Q><Q><S><R><D><V><P><H><A><T><N><T><A><N><A><I><T><E><H><M><T><K><G><K><T><I><T><V><E><S><D><V><L><R><L><V><I><D><T><L><G><G><D><V><I><E><S><D><L><L><A><H><K><A><S><L><D><S><T><D><P><L><K><L><L><T><T><E><G...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb...
Q7VPM2
B1W5H1
UREG1_STRGG
Urease accessory protein UreG 1
Streptomyces
<M><T><R><T><P><T><G><V><P><M><H><L><G><H><T><H><D><A><P><A><A><V><S><A><D><A><T><R><P><D><G><T><R><R><A><L><R><I><G><L><G><G><P><V><G><S><G><K><T><A><T><V><A><A><L><C><R><E><L><R><D><R><L><S><I><A><V><V><T><N><D><I><Y><T><R><E><D><A><D><F><L><L><K><N><A><V><L><P><P><E><R><I><Q><A><V><E><T><G><A><C><P><H><T><A><I><R><D...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B1W5H1
B4TQK0
THIG_SALSV
Thiazole synthase
Salmonella
<M><L><R><I><A><D><K><T><F><N><S><H><L><F><T><G><T><G><K><F><A><S><S><Q><L><M><V><E><A><I><R><A><S><G><S><Q><L><V><T><L><A><M><K><R><V><D><L><R><Q><H><N><D><A><I><L><M><P><L><I><E><A><G><V><T><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><Q><L><A><R><E><A><L><G><T><H><W><L><K><L><E><I><H><P><D><A><R><W><L><L><P...
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP>
B4TQK0
Q8NB15
ZN511_HUMAN
Zinc finger protein 511
Homo
<M><Q><L><P><P><A><L><C><A><R><L><A><A><G><P><G><A><A><E><P><L><P><V><E><R><D><P><A><A><G><A><A><P><F><R><F><V><A><R><P><V><R><F><P><R><E><H><Q><F><F><E><D><G><D><V><Q><R><H><L><Y><L><Q><D><V><I><M><Q><V><A><D><V><P><E><K><P><R><V><P><A><F><A><C><Q><V><A><G><C><C><Q><V><F><D><A><L><D><D><Y><E><H><H><Y><H><T><L><H><G><N...
May be involved in transcriptional regulation.<BOP>
Q8NB15
Q11DI2
TOLB_CHESB
Tol-Pal system protein TolB
unclassified Chelativorans
<M><R><N><F><F><K><T><A><V><A><I><T><S><L><V><M><G><L><V><A><M><A><V><V><P><A><R><A><L><V><E><I><D><V><N><R><G><V><V><E><P><V><P><I><A><I><T><D><F><L><S><A><G><G><R><G><A><E><I><S><A><V><I><A><A><D><L><K><R><S><G><L><F><A><P><I><D><R><G><A><F><I><E><K><I><S><N><P><D><V><A><P><R><F><E><D><W><K><V><I><N><A><Q><A><I><V><T...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
Q11DI2
Q8U0J5
TRPB2_PYRFU
Tryptophan synthase beta chain 2
Pyrococcus
<M><K><V><V><L><P><D><G><R><I><P><R><R><W><Y><N><I><L><P><D><L><P><E><P><L><A><P><P><L><D><P><E><T><N><E><P><V><D><P><K><K><L><E><R><I><F><A><K><E><L><V><K><Q><E><M><S><T><K><R><Y><I><K><I><P><E><E><V><R><K><M><Y><S><K><I><G><R><P><T><P><L><F><R><A><T><N><L><E><K><Y><L><N><T><P><A><R><I><Y><F><K><F><E><G><A><T><V><T><G...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
Q8U0J5
A7GTW9
TRMB_BACCN
tRNA(m7G46)-methyltransferase
Bacillus cereus group
<M><R><L><R><H><K><P><Y><A><M><D><R><I><K><E><Y><S><Q><F><V><I><G><N><P><E><E><H><R><G><N><W><K><E><L><F><G><N><D><H><P><I><H><I><E><V><G><T><G><R><G><R><F><V><Y><E><M><A><K><A><N><P><D><I><N><Y><I><G><I><E><K><F><T><S><V><I><V><D><A><L><D><K><L><I><E><K><E><L><P><N><L><K><L><I><N><K><D><A><E><D><L><T><V><F><F><T><K><G...
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP>
A7GTW9
Q3AX81
TRHO_SYNS9
tRNA hydroxylation protein O
unclassified Synechococcus
<M><S><R><L><Q><V><A><A><F><Y><A><F><T><P><L><N><E><Q><Q><R><A><S><L><L><S><D><L><P><D><M><A><M><T><N><S><V><L><G><S><I><L><V><A><H><E><G><V><N><G><T><I><S><G><P><E><A><G><V><E><A><L><L><Q><S><L><R><T><S><L><A><L><G><C><E><H><F><E><R><L><E><V><K><R><S><W><A><D><Q><A><V><F><R><R><F><K><A><R><A><K><K><E><I><V><T><M><G><V...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
Q3AX81
Q39QP4
TATA_GEOMG
Sec-independent protein translocase protein TatA
Geobacter
<M><F><G><I><G><M><P><E><L><I><V><I><L><V><I><V><L><V><V><F><G><A><G><R><L><P><E><I><G><G><A><L><G><K><S><I><R><N><F><K><K><A><S><D><G><K><D><E><I><E><I><K><P><E><K><K><D><D><P><S><K>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
Q39QP4
Q10953
WRM1_CAEEL
Worm armadillo protein 1
Caenorhabditis
<M><D><V><D><C><A><E><T><F><S><Q><P><C><T><P><L><N><F><N><P><M><T><P><S><T><S><R><V><S><T><P><V><R><P><S><S><T><M><S><A><R><Q><Y><S><G><S><P><F><K><A><Q><P><Q><N><M><E><P><S><N><S><R><V><Q><E><L><R><E><A><A><V><G><K><R><S><Y><T><N><A><W><M><Q><G><T><Y><A><P><P><Q><M><A><G><Q><Q><Q><R><F><S><R><P><P><S><V><I><G><S><T><M...
Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Component...
Q10953
Q1BYC0
UBID_BURCA
Polyprenyl p-hydroxybenzoate decarboxylase
Burkholderia cepacia complex
<M><K><Y><K><D><L><R><D><F><I><Q><R><L><E><A><L><G><E><L><R><R><V><T><Q><P><V><S><P><V><L><E><M><T><E><L><C><D><R><V><L><R><A><G><G><P><A><L><L><F><N><A><P><P><G><N><A><F><P><V><L><G><N><L><F><G><T><P><R><R><V><A><L><G><M><G><V><D><A><G><D><D><A><A><L><G><S><L><R><D><L><G><R><L><L><S><A><L><K><E><P><D><P><P><K><S><L><K...
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP>
Q1BYC0
O43298
ZBT43_HUMAN
ZnF-x
Homo
<M><E><P><G><T><N><S><F><R><V><E><F><P><D><F><S><S><T><I><L><Q><K><L><N><Q><Q><R><Q><Q><G><Q><L><C><D><V><S><I><V><V><Q><G><H><I><F><R><A><H><K><A><V><L><A><A><S><S><P><Y><F><C><D><Q><V><L><L><K><N><S><R><R><I><V><L><P><D><V><M><N><P><R><V><F><E><N><I><L><L><S><S><Y><T><G><R><L><V><M><P><A><P><E><I><V><S><Y><L><T><A><A...
May be involved in transcriptional regulation.<BOP>
O43298
C4ZA66
XPT_AGARV
Xanthine phosphoribosyltransferase
Lachnospiraceae incertae sedis
<M><K><E><L><Q><D><R><I><L><K><D><G><Q><V><I><G><T><N><I><L><K><V><N><K><F><I><N><H><Q><V><D><P><V><L><M><E><H><I><G><E><D><F><A><N><H><F><A><D><K><G><I><T><K><V><V><T><I><E><S><S><G><I><A><P><A><L><M><A><A><A><K><M><N><V><P><L><V><I><L><K><K><Q><P><S><K><T><L><H><N><D><L><Y><Q><T><Q><V><T><S><F><T><T><E><K><S><Y><E><L...
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP>
C4ZA66
Q6AFR0
TRMB_LEIXX
tRNA(m7G46)-methyltransferase
Leifsonia
<M><E><P><A><P><L><V><R><P><R><S><Y><V><V><R><G><R><K><T><D><A><Q><Q><R><A><I><A><E><F><W><P><A><F><G><V><D><F><A><G><G><L><L><D><L><D><A><L><F><G><R><T><A><P><R><T><V><E><I><G><F><G><N><G><E><N><L><L><A><L><A><E><R><H><P><E><R><D><F><L><G><V><E><V><H><G><A><G><V><G><R><V><F><A><A><M><R><E><R><G><L><S><N><I><R><V><I><R...
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP>
Q6AFR0
P31863
TBB2_HYPRU
Beta-2-tubulin
Trichoderma
<M><R><E><I><V><Y><I><Q><T><G><Q><C><G><N><Q><I><G><A><A><F><W><Q><T><I><S><G><E><H><G><L><D><S><N><G><I><Y><N><G><S><S><E><L><Q><L><E><R><M><N><V><Y><F><N><E><A><S><N><N><K><Y><V><P><R><A><V><L><V><D><L><E><P><G><T><M><D><A><V><R><A><G><P><F><G><Q><L><F><R><P><D><N><F><I><F><G><Q><S><S><A><G><N><N><W><A><K><G><H><Y><T...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
P31863
Q9SUE0
YMG12_ARATH
YGGT family protein YLMG1-2
Arabidopsis
<M><A><S><F><T><T><N><S><L><A><L><R><A><S><I><L><A><N><P><R><L><P><P><P><I><I><R><P><R><L><S><L><P><R><K><L><S><F><N><L><S><L><H><N><A><R><T><I><V><S><S><A><V><T><S><S><S><P><V><L><S><S><K><P><P><S><Q><F><P><F><S><D><S><T><R><S><I><T><T><L><V><L><L><A><G><V><V><I><K><S><L><I><Q><K><L><S><V><A><I><V><N><L><S><P><Q><I><Q...
Not required for the biogenesis and accumulation of native cytochrome b6 in the thylakoid membrane. Not functionally involved in the pathway for covalent binding of the c-type heme to cytochrome b6.<BOP>
Q9SUE0
B3QXJ6
TRMD_CHLT3
tRNA [GM37] methyltransferase
Chloroherpeton
<M><R><V><D><I><I><S><V><L><P><D><F><F><D><S><P><L><A><N><G><L><L><R><I><A><R><E><K><Q><R><L><Q><L><H><V><H><S><L><R><E><Y><G><L><G><K><Y><K><Q><V><D><D><T><P><F><G><G><G><A><G><M><V><L><R><V><E><P><V><F><A><C><I><E><K><L><K><A><D><R><D><Y><D><E><V><I><F><F><T><P><D><G><K><Q><F><N><Q><S><E><A><N><R><H><A><L><D><R><N><L...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
B3QXJ6
Q9RDV3
TRMD_MYCGA
tRNA [GM37] methyltransferase
Mycoplasma
<M><K><I><V><V><L><T><L><F><D><D><F><V><R><S><Y><Y><D><F><S><I><I><K><N><A><L><D><K><K><A><V><E><L><E><V><I><N><F><R><Q><Y><A><N><D><K><H><K><T><V><D><D><T><I><Y><G><G><S><A><G><M><L><L><K><L><E><P><L><V><N><C><L><R><D><I><K><Q><N><Q><F><K><D><P><N><K><I><R><T><Y><L><L><S><P><Q><G><E><V><Y><D><Q><N><K><A><V><A><L><S><Q...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q9RDV3
Q8GBB2
TRMI_THET2
tRNA(m1A58)-methyltransferase
Thermus
<M><A><W><P><G><P><L><L><L><K><D><R><K><G><R><A><Y><L><V><F><P><K><E><G><G><V><F><H><H><H><K><G><S><V><P><H><E><A><L><L><E><A><G><P><G><G><V><V><R><T><H><L><G><E><E><L><S><V><H><R><P><T><L><E><E><Y><L><L><H><M><K><R><S><A><T><P><T><Y><P><K><D><A><S><A><M><V><T><L><L><D><L><A><P><G><M><R><V><L><E><A><G><T><G><S><G><G><L...
Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. Is required for cell growth at extreme temperatures.<BOP>
Q8GBB2
Q4WHN8
VPS27_ASPFU
Vacuolar protein sorting-associated protein 27
Aspergillus subgen. Fumigati
<M><A><G><W><F><S><S><T><S><P><L><D><E><Q><V><E><R><A><T><S><S><S><L><E><D><M><A><L><N><L><E><I><S><D><L><I><R><S><K><S><V><Q><P><K><E><A><M><R><S><L><K><R><R><L><E><N><R><N><P><N><V><Q><I><A><T><L><K><L><T><D><T><C><V><K><N><G><G><S><H><F><L><A><E><I><A><S><R><E><F><M><D><N><L><V><S><L><L><T><T><E><G><A><P><L><N><T><D...
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP>
Q4WHN8
Q3AJ48
TRHO_SYNSC
tRNA hydroxylation protein O
unclassified Synechococcus
<M><N><P><S><N><L><E><P><G><L><A><N><D><S><R><L><L><V><A><A><F><Y><A><F><T><P><L><D><D><E><R><R><E><T><L><L><S><S><L><P><T><L><A><R><N><G><S><V><L><G><S><V><L><V><A><H><E><G><V><N><G><T><I><S><G><P><E><S><A><V><D><A><V><L><D><H><L><R><T><S><F><D><L><G><D><E><H><Y><A><R><L><E><V><K><R><S><W><A><E><K><P><V><F><R><R><F><K...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
Q3AJ48
Q31JQ7
TSAC_HYDCU
tRNA threonylcarbamoyladenosine biosynthesis protein TsaC
Hydrogenovibrio
<M><N><C><P><L><L><T><I><K><A><A><A><K><L><I><T><E><G><G><V><L><A><Y><P><T><E><A><V><Y><G><L><G><C><D><P><L><N><K><D><A><F><Q><Q><L><L><R><L><K><Q><R><P><L><E><K><G><V><I><L><I><A><S><S><I><A><Q><I><E><P><F><V><K><L><H><N><Q><A><W><T><E><K><V><L><A><S><W><Q><V><L><N><Q><P><V><T><W><V><L><P><A><T><D><N><V><P><E><W><I><T...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.<BOP>
Q31JQ7
Q17VS4
UREE_HELAH
Urease accessory protein UreE
Helicobacter
<M><I><I><E><R><L><T><G><N><L><R><D><L><N><P><L><D><F><K><V><D><Y><V><D><L><E><W><F><E><T><R><K><K><I><A><R><F><K><T><R><Q><G><K><D><I><A><I><R><L><K><D><A><P><K><L><G><L><S><Q><G><D><I><L><F><K><E><E><K><E><I><I><A><I><N><I><L><D><S><E><V><I><H><I><Q><A><K><S><V><A><E><V><A><K><I><C><Y><E><I><G><N><R><H><A><T><L><Y><Y...
Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP>
Q17VS4
Q1AVV7
YBEY_RUBXD
Endoribonuclease YbeY
Rubrobacter
<M><P><F><R><V><E><V><L><N><E><T><S><G><G><A><R><L><T><P><E><R><A><T><E><L><C><R><R><A><F><V><E><R><G><L><D><P><E><R><M><G><E><L><S><V><A><L><V><E><P><E><V><I><H><D><L><N><L><K><F><R><N><K><D><A><P><T><D><V><L><S><F><E><V><D><G><P><Y><G><E><M><V><G><E><I><V><I><C><P><G><C><A><E><M><D><L><E><E><L><V><V><H><G><A><L><H><L...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
Q1AVV7
B9MDW9
TATA_ACIET
Sec-independent protein translocase protein TatA
Diaphorobacter
<M><G><S><F><S><I><W><H><W><L><I><V><L><L><I><V><V><M><V><F><G><T><K><K><L><K><N><I><G><S><D><L><G><G><A><V><K><G><F><K><D><G><M><K><D><G><A><S><T><D><D><S><A><T><T><S><A><P><A><G><Q><V><T><N><N><S><A><A><A><D><K><T><T><I><D><V><E><A><K><H><K><S>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
B9MDW9
Q6NDN5
TRPA_RHOPA
Tryptophan synthase alpha chain
Rhodopseudomonas
<M><T><T><R><I><D><T><R><F><G><E><L><K><Q><Q><G><R><P><A><L><V><T><F><V><M><A><G><D><P><D><L><D><T><S><L><Q><I><L><K><V><L><P><A><A><G><A><D><V><I><E><I><G><M><P><F><T><D><P><M><A><D><G><P><A><I><Q><A><A><G><L><R><A><L><K><A><G><T><T><L><K><K><T><L><G><L><V><R><D><F><R><A><T><D><N><A><T><P><L><V><L><M><G><Y><Y><N><P><I...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q6NDN5
Q9VM35
U2QL1_DROME
E2Q-like ubiquitin-conjugating enzyme CG4502
Sophophora
<M><S><S><R><S><K><E><R><V><V><T><A><F><R><K><I><F><H><K><S><S><N><N><N><N><N><N><N><N><N><H><N><N><N><I><N><N><N><N><N><N><D><K><V><D><G><A><T><G><S><S><P><N><I><N><N><N><N><N><N><N><N><N><N><N><N><H><D><G><A><A><A><P><S><S><A><G><G><V><A><V><A><G><G><A><V><G><S><S><G><S><S><G><A><A><K><N><A><V><V><R><M><A><A><E><Q><A...
Catalyzes the covalent attachment of ubiquitin to other proteins.<BOP>
Q9VM35
Q5HTL6
UVRC_CAMJR
Excinuclease ABC subunit C
Campylobacter
<M><I><K><E><N><L><E><N><E><L><K><T><L><P><N><S><A><G><V><Y><Q><Y><F><N><Q><E><G><K><L><L><Y><V><G><K><A><K><N><L><K><N><R><V><K><S><Y><F><A><F><T><P><N><L><H><A><N><P><R><N><S><L><R><I><Q><K><M><I><E><E><T><V><H><L><E><F><I><A><T><N><S><E><A><D><A><L><I><L><E><N><S><F><I><K><Q><L><H><P><K><Y><N><I><L><L><R><D><D><K><T...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q5HTL6
Q9P6R0
TF3B_SCHPO
TFIIB-related factor
Schizosaccharomyces
<M><G><C><P><N><C><G><S><T><T><F><E><S><D><T><A><S><G><N><T><Y><C><T><Q><C><G><V><V><V><E><Q><D><A><I><V><S><E><V><T><F><G><E><A><S><T><G><A><A><V><V><Q><G><S><L><V><S><N><D><Q><T><H><A><R><T><F><G><G><P><Y><R><N><Q><G><S><V><E><S><R><E><L><T><I><A><N><G><R><R><R><I><S><A><L><A><I><A><L><K><L><N><E><R><H><I><E><A><A><V...
General activator of RNA polymerase III transcription.<BOP>
Q9P6R0
Q6PEY2
TBA3E_HUMAN
null
Homo
<M><R><E><C><I><S><I><H><V><G><Q><A><G><V><Q><I><G><N><A><C><W><E><L><Y><C><L><E><H><G><I><Q><P><D><G><Q><M><P><S><D><K><T><I><G><G><G><D><D><S><F><N><T><F><F><S><E><T><G><A><G><K><H><V><P><R><A><V><F><V><D><L><E><P><T><V><V><D><E><V><R><T><G><T><Y><R><Q><L><F><H><P><E><Q><L><I><T><G><K><E><D><A><A><S><N><Y><A><R><G><H...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
Q6PEY2
P0CM61
VAC8_CRYNB
Vacuolar protein 8
Cryptococcus neoformans species complex
<M><G><S><A><L><S><S><C><C><S><P><R><R><K><N><A><Y><E><P><L><L><L><E><T><E><R><E><A><V><A><D><L><L><Q><Y><L><E><N><R><S><T><T><N><F><F><A><G><S><P><L><A><A><L><T><T><L><S><F><S><E><N><V><D><L><Q><R><S><A><A><L><A><F><A><E><I><T><E><K><E><V><R><E><V><G><R><D><T><L><D><P><V><L><Y><L><L><S><S><H><D><P><E><V><Q><R><A><A><S...
Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.<BOP>
P0CM61
O67409
TRPB2_AQUAE
Tryptophan synthase beta chain 2
Aquifex
<M><R><K><F><L><L><S><E><G><E><I><P><K><K><W><L><N><I><L><P><L><L><P><E><P><L><E><P><P><L><D><P><E><T><M><E><P><V><K><P><E><K><L><L><A><I><F><P><E><P><L><V><E><Q><E><V><S><D><K><E><W><I><D><I><P><E><E><V><L><D><I><Y><S><L><W><R><P><T><P><L><H><R><A><K><N><L><E><E><F><L><G><T><P><A><K><I><F><Y><K><N><E><S><V><S><P><P><G...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
O67409
Q54VP1
VPS55_DICDI
Vacuolar protein sorting-associated protein 55 homolog
Dictyostelium
<M><G><H><D><I><K><G><F><S><C><A><F><A><V><G><L><L><F><N><I><L><A><C><I><V><S><H><S><G><Y><P><I><I><V><V><A><S><Y><F><L><A><P><F><P><N><I><L><C><R><N><R><D><S><F><S><S><E><K><G><T><F><E><D><I><G><L><F><L><T><G><L><F><I><T><S><G><F><A><I><P><M><I><L><A><H><S><D><I><I><S><G><K><A><L><A><F><S><M><A><G><G><V><T><V><Y><A><T...
Involved in endosomal protein transport.<BOP>
Q54VP1
Q2A2E9
UVRC_FRATH
Excinuclease ABC subunit C
Francisella
<M><I><V><D><N><S><K><D><F><D><L><K><S><F><L><A><N><L><T><T><H><S><G><V><Y><R><M><L><D><K><H><G><E><I><I><Y><V><G><K><A><K><N><L><K><N><R><I><N><S><Y><F><S><K><G><A><K><D><S><K><T><L><M><M><V><E><Q><I><A><R><I><E><I><T><I><T><P><S><D><Y><E><A><Y><L><L><E><N><N><L><I><K><Q><H><R><P><K><Y><N><I><L><F><K><D><D><K><S><Y><P...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q2A2E9
Q46LZ8
YIDD_PROMT
Putative membrane protein insertion efficiency factor
Prochlorococcus
<M><L><T><K><I><N><K><A><I><A><L><V><F><V><S><L><I><S><F><Y><Q><K><W><I><S><P><L><F><G><P><S><C><R><F><I><P><S><C><S><A><Y><G><I><E><A><V><N><K><H><G><P><W><R><G><G><W><L><T><L><K><R><L><S><K><C><H><P><L><T><P><C><G><C><D><P><V><P><E><K>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q46LZ8
Q7MZB6
UBIA_PHOLL
4-HB polyprenyltransferase
Photorhabdus
<M><A><G><S><M><A><Q><S><K><W><L><A><Y><C><R><L><M><R><I><N><K><P><I><G><A><L><L><L><L><W><P><T><F><W><A><L><W><M><A><G><K><G><I><P><D><M><H><I><L><L><V><F><T><A><G><V><F><L><M><R><A><A><G><C><A><I><N><D><F><A><D><R><K><F><D><G><Y><V><E><R><T><K><T><R><P><L><P><S><G><A><I><S><E><K><E><S><K><I><L><F><V><V><L><A><L><I><S...
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-...
Q7MZB6
P75132
TRMD_MYCPN
tRNA [GM37] methyltransferase
Mycoplasma
<M><K><I><T><V><L><T><L><F><E><Q><V><V><W><P><Y><L><N><A><S><I><M><A><Q><A><Q><K><A><K><L><V><E><F><E><V><I><N><W><R><Q><Y><C><K><D><K><H><Q><T><V><D><D><M><A><Y><G><G><G><G><G><M><V><L><K><A><E><P><I><L><K><A><L><K><A><C><R><T><P><Q><S><K><V><V><L><L><S><P><E><G><Q><Q><F><S><Q><P><M><A><Q><A><L><T><Q><T><E><H><L><I><L...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
P75132
Q896F1
YQGF_CLOTE
Putative pre-16S rRNA nuclease
Clostridium
<M><R><I><L><G><L><D><V><G><D><R><T><I><G><V><A><I><S><D><P><L><G><W><T><A><Q><G><V><K><T><I><K><R><S><N><L><K><N><D><I><K><E><I><E><D><I><C><N><E><Y><K><V><D><K><I><V><S><G><L><P><K><N><M><N><G><T><L><G><P><Q><S><E><K><V><T><E><F><C><D><I><L><K><K><E><L><E><K><E><I><I><M><W><D><E><R><L><T><T><V><A><A><H><K><A><M><I><E...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
Q896F1
B7LV66
THIM_ESCF3
4-methyl-5-beta-hydroxyethylthiazole kinase
Escherichia
<M><Q><P><D><L><L><S><R><K><T><A><A><L><T><L><Q><K><F><H><T><L><S><P><L><T><H><C><M><T><N><D><V><V><Q><T><F><T><A><N><T><L><L><A><L><G><A><S><P><A><M><V><I><E><T><E><E><A><S><Q><F><A><A><V><A><S><A><L><L><I><N><V><G><T><L><T><Q><A><R><A><H><A><M><R><A><A><V><V><H><A><K><R><V><K><T><P><W><T><L><D><P><V><A><V><G><S><L><D...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
B7LV66
Q3T086
TPC6A_BOVIN
Trafficking protein particle complex subunit 6A
Bos
<M><A><D><P><A><L><F><E><F><L><H><T><E><M><V><A><E><L><W><A><Q><D><P><D><P><G><P><G><G><Q><K><T><S><L><L><V><L><E><G><M><G><F><R><V><G><Q><A><L><G><E><R><L><P><R><E><T><L><T><F><R><E><E><L><D><I><L><K><F><L><C><K><D><L><W><V><A><V><F><H><K><Q><M><D><S><L><R><T><N><H><Q><G><T><Y><V><L><Q><D><N><S><F><P><L><L><V><R><M><A...
May play a role in vesicular transport during the biogenesis of melanosomes.<BOP>
Q3T086
Q4FVG3
UBIG_PSYA2
3-demethylubiquinone 3-O-methyltransferase
Psychrobacter
<M><A><E><N><T><V><N><A><I><N><V><D><P><S><E><V><E><K><F><N><K><L><A><G><E><W><W><N><K><T><G><A><F><A><T><L><H><E><I><N><P><L><R><L><N><W><I><E><E><N><V><K><C><G><Y><V><S><A><D><H><Q><K><T><A><E><M><G><L><A><G><K><K><V><L><D><V><G><C><G><G><G><I><L><S><E><A><M><A><R><R><G><A><D><V><T><G><I><D><L><G><T><E><N><L><K><A><A...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
Q4FVG3
Q6ITC0
VKT2_PSEAU
Kunitz-type serine protease inhibitor mulgin-2
Pseudechis
<M><S><S><G><G><L><F><L><L><L><G><L><L><T><L><W><E><V><L><T><P><V><S><S><K><D><R><P><K><F><C><E><L><P><P><D><S><G><S><C><K><G><S><F><Q><A><F><Y><Y><H><P><V><H><R><T><C><L><E><F><I><Y><G><G><C><E><G><N><D><N><N><F><K><T><I><D><E><C><K><R><T><C><A><A>
Serine protease inhibitor.<BOP>
Q6ITC0
Q9P1Q0
VPS54_HUMAN
Tumor antigen SLP-8p
Homo
<M><A><S><S><H><S><S><S><P><V><P><Q><G><S><S><S><D><V><F><F><K><I><E><V><D><P><S><K><H><I><R><P><V><P><S><L><P><D><V><C><P><K><E><P><T><G><D><S><H><S><L><Y><V><A><P><S><L><V><T><D><Q><H><R><W><T><V><Y><H><S><K><V><N><L><P><A><A><L><N><D><P><R><L><A><K><R><E><S><D><F><F><T><K><T><W><G><L><D><F><V><D><T><E><V><I><P><S><F...
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal so...
Q9P1Q0
B1ZHN6
UREG1_METPB
Urease accessory protein UreG 1
Methylorubrum
<M><A><S><L><N><G><P><L><R><V><G><I><G><G><P><V><G><S><G><K><T><A><L><M><E><Q><L><C><R><R><F><R><D><R><Y><E><I><C><A><I><T><N><D><I><Y><T><K><E><D><A><R><I><L><T><V><A><G><A><L><P><E><E><R><I><L><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><I><N><L><A><A><V><A><E><M><R><R><R><F><P><K><L><D><L><V><L><I><E><S><G><G...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B1ZHN6
A0KYM0
TIG_SHESA
PPIase
Shewanella
<M><Q><V><S><V><E><A><T><Q><G><L><E><R><R><L><T><I><S><V><P><A><E><Q><I><E><K><L><V><K><D><S><L><Q><R><E><A><K><R><A><R><I><P><G><F><R><P><G><K><V><P><V><T><V><I><N><K><R><Y><G><A><A><I><R><Q><D><I><T><G><E><V><M><Q><R><N><F><I><E><A><I><I><A><E><K><L><N><P><A><G><A><P><T><F><V><P><G><A><T><D><G><E><K><F><E><F><V><A><T...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A0KYM0
Q4FQ48
UVRC_PSYA2
null
Psychrobacter
<M><V><N><V><S><V><L><S><P><V><D><D><K><K><A><R><L><K><H><L><I><Q><R><L><P><N><L><P><G><V><Y><K><M><L><G><K><N><G><D><I><L><Y><V><G><K><A><K><S><L><K><S><R><V><N><S><Y><F><A><K><T><I><D><H><P><K><T><R><A><L><V><A><R><I><H><N><I><E><T><I><I><T><R><S><E><T><E><A><L><L><L><E><Q><N><L><I><K><E><Y><R><P><P><Y><N><V><L><L><R...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q4FQ48
Q6D8D8
UPPS_PECAS
Undecaprenyl pyrophosphate synthase
Pectobacterium
<M><P><S><D><N><Q><K><N><T><N><D><L><P><L><A><G><P><R><H><V><A><I><I><M><D><G><N><G><R><W><A><K><S><R><G><K><M><R><I><F><G><H><Q><A><G><V><K><A><V><R><R><S><V><S><F><A><V><N><H><G><L><D><A><L><T><L><Y><A><F><S><S><E><N><W><N><R><P><A><Q><E><V><S><A><L><M><E><L><F><V><R><A><L><D><S><E><V><K><S><L><H><K><H><N><V><R><L><R...
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide c...
Q6D8D8
Q92ES8
TATC_LISIN
Sec-independent protein translocase protein TatC
Listeria
<M><T><E><V><S><M><S><L><T><G><H><L><K><E><L><R><T><R><L><L><I><I><L><L><S><F><F><L><A><F><F><V><G><L><F><V><S><K><P><L><I><L><F><L><Q><K><D><D><L><P><K><E><V><I><L><H><V><F><K><V><T><D><A><F><Q><I><Y><I><E><M><A><F><I><I><G><L><I><L><V><F><P><V><I><L><Y><Q><L><W><A><F><V><K><P><G><L><H><A><S><E><Q><R><I><T><L><R><Y><I...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.<BOP>
Q92ES8
P96579
YDAF_BACSU
Putative ribosomal N-acetyltransferase YdaF
Bacillus
<M><F><T><C><K><V><N><E><H><I><T><I><R><L><L><E><P><K><D><A><E><R><L><A><E><L><I><I><Q><N><Q><Q><R><L><G><K><W><L><F><F><A><E><N><P><S><S><A><D><T><Y><R><E><T><I><I><P><D><W><R><R><Q><Y><A><D><L><N><G><I><E><A><G><L><L><Y><D><G><S><L><C><G><M><I><S><L><H><N><L><D><Q><V><N><R><K><A><E><I><G><Y><W><I><A><K><E><F><E><G><K...
Putative N-acetyltransferase. May act on ribosomal proteins (Potential).<BOP>
P96579
Q750F0
YPI1_ASHGO
Type 1 phosphatases regulator YPI1
Eremothecium
<M><S><S><N><N><Q><E><S><L><A><N><R><S><H><T><V><T><V><S><E><T><S><Q><I><L><Q><L><R><A><N><Q><T><E><Q><V><P><K><L><A><K><K><E><Q><K><S><K><V><R><W><D><E><N><V><V><D><N><E><H><M><N><K><K><K><T><K><I><C><C><I><F><H><P><Q><Q><N><F><D><D><E><D><G><G><E><C><E><H><A><S><S><S><A><S><S><S><S><S><S><E><S><E><N><D><T><S><M><D><F...
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.<BOP>
Q750F0
O95159
ZFPL1_HUMAN
Zinc finger protein MCG4
Homo
<M><G><L><C><K><C><P><K><R><K><V><T><N><L><F><C><F><E><H><R><V><N><V><C><E><H><C><L><V><A><N><H><A><K><C><I><V><Q><S><Y><L><Q><W><L><Q><D><S><D><Y><N><P><N><C><R><L><C><N><I><P><L><A><S><R><E><T><T><R><L><V><C><Y><D><L><F><H><W><A><C><L><N><E><R><A><A><Q><L><P><R><N><T><A><P><A><G><Y><Q><C><P><S><C><N><G><P><I><F><P><P...
Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.<BOP>
O95159
Q6R3K8
YSL4_ARATH
Protein YELLOW STRIPE LIKE 4
Arabidopsis
<M><E><T><E><I><P><R><S><T><E><I><S><E><T><L><L><L><P><E><T><N><L><D><H><G><E><Y><V><P><E><W><K><E><Q><I><T><I><R><G><L><I><S><S><A><L><L><G><I><L><F><C><I><I><T><H><K><L><N><L><T><I><G><I><I><P><S><L><N><V><A><A><G><L><L><G><F><F><F><I><K><S><W><T><G><F><L><S><K><L><G><F><L><S><K><P><F><T><K><Q><E><N><T><V><I><Q><T><C...
May be involved in the transport of nicotianamine-chelated metals.<BOP>
Q6R3K8
Q9RP19
UREG_SPOPA
Urease accessory protein UreG
Sporosarcina
<M><K><T><I><H><L><G><I><G><G><P><V><G><S><G><K><T><T><L><V><K><T><L><S><E><A><L><K><E><E><Y><S><I><A><V><I><T><N><D><I><Y><T><R><E><D><A><N><F><L><I><N><E><N><I><L><E><K><D><R><I><I><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><M><N><F><E><A><I><E><E><L><K><N><R><F><D><D><L><E><I><I><L><L><E><S><G><G><D><N><L><S...
Facilitates the functional incorporation of the urease nickel metallocenter. Binds a maximum of 4 Ni(2+) and 2 Zn(2+) ions per homodimer. The affinity for Zn(2+) is 10-fold higher than that for Ni(2+). This process requires GTP hydrolysis.<BOP>
Q9RP19
Q6PD29
ZN513_MOUSE
Zinc finger protein 513
Mus
<M><P><R><R><K><Q><S><H><P><Q><P><V><K><C><E><G><V><K><V><D><T><E><D><S><F><D><E><G><P><G><A><L><V><L><E><S><D><L><L><L><G><Q><D><L><E><F><E><E><E><E><E><E><D><E><G><D><G><H><N><D><Q><L><M><G><F><E><R><D><S><E><G><D><S><Q><G><A><R><P><G><L><P><Y><G><L><S><D><D><E><S><G><G><G><R><A><L><S><A><E><S><E><V><E><E><P><A><R><G...
Transcriptional regulator that plays a role in retinal development and maintenance.<BOP>
Q6PD29
Q39R76
TRUD_GEOMG
tRNA-uridine isomerase D
Geobacter
<M><S><G><E><K><R><Y><L><T><A><G><L><P><G><T><G><G><T><I><K><E><T><A><D><D><F><V><V><E><E><I><P><L><Y><L><P><C><G><E><G><E><H><V><Y><A><L><I><E><K><R><G><V><T><T><L><D><A><I><R><R><L><A><R><A><L><K><L><S><E><R><D><V><G><Y><A><G><M><K><D><A><R><G><V><T><R><Q><T><V><S><L><P><R><M><K><P><E><E><V><L><A><L><E><L><P><G><I><R...
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP>
Q39R76
O26979
XERA_METTH
Tyrosine recombinase XerA
Methanothermobacter
<M><V><D><T><M><N><M><K><R><E><S><E><E><R><Q><G><L><L><E><R><Y><N><F><P><E><L><I><E><D><Y><L><I><E><L><E><I><R><N><Y><S><P><N><T><I><K><T><Y><K><S><I><V><K><N><F><Y><E><F><L><M><N><E><D><D><L><Y><D><D><R><R><V><L><R><S><F><K><R><Y><I><Q><Y><L><K><R><D><K><K><V><T><Q><N><Y><I><Y><L><V><T><V><V><V><K><K><F><F><E><F><S><G...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.<BOP>
O26979