accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q5LC87 | NHAA_BACFN | Sodium/proton antiporter NhaA | Bacteroides | <M><T><V><L><R><S><M><K><D><F><S><S><M><N><I><T><A><S><I><L><L><F><V><T><A><I><A><A><A><V><I><A><N><S><P><A><A><S><V><Y><Q><E><F><L><S><H><E><L><H><F><R><I><G><G><F><N><L><L><S><H><A><G><H><N><L><T><M><I><E><F><I><N><D><G><L><M><T><I><F><F><L><M><V><G><L><E><I><K><R><E><L><L><V><G><E><L><S><S><F><R><K><A><A><L><P><F><I... | Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.<BOP> | Q5LC87 |
A1UJ38 | TIG_MYCSK | PPIase | unclassified Mycobacterium | <M><K><S><T><V><E><K><L><S><P><T><R><V><R><I><N><V><E><V><P><F><T><E><L><E><P><D><F><D><R><A><F><K><E><L><A><K><Q><V><R><L><P><G><F><R><P><G><K><A><P><R><K><L><L><E><A><R><V><G><R><E><A><M><L><D><Q><V><V><G><E><A><V><P><G><R><Y><T><E><A><V><T><S><S><D><V><Q><P><L><G><Q><P><E><I><E><I><T><K><K><E><Y><G><E><D><L><V><F><T... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | A1UJ38 |
B2IA21 | UBIE_XYLF2 | Demethylmenaquinone methyltransferase | Xylella | <M><S><E><S><S><E><K><T><S><T><T><H><F><G><F><R><Q><V><A><A><K><D><K><K><T><L><V><A><E><V><F><T><S><V><S><R><R><Y><D><L><M><N><D><L><M><S><L><G><I><H><R><A><W><K><R><Y><F><V><A><T><A><Q><V><K><S><G><D><R><V><L><D><L><A><G><G><T><G><D><I><A><M><L><L><K><N><R><V><G><A><E><G><S><I><V><L><G><D><I><N><A><S><M><L><S><V><G><R... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | B2IA21 |
A4Y5X9 | FABA_SHEPC | Trans-2-decenoyl-[acyl-carrier-protein] isomerase | Shewanella | <M><N><K><A><N><S><F><N><K><E><E><L><I><A><C><G><H><G><K><L><F><G><P><N><S><P><R><L><P><V><D><N><M><L><M><I><D><R><I><V><T><I><N><D><N><G><G><E><F><G><K><G><E><I><V><A><E><L><D><I><N><P><E><L><W><F><F><D><C><H><F><I><S><D><P><V><M><P><G><C><L><G><L><D><A><M><W><Q><L><V><G><F><Y><L><G><W><E><G><A><E><G><K><G><R><A><L><G... | Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active ... | A4Y5X9 |
A1QZS8 | RS8_BORT9 | 30S ribosomal protein S8 | Borrelia | <M><A><V><T><H><S><V><G><D><M><L><T><K><I><R><N><A><S><R><V><K><H><E><S><V><D><L><K><M><S><K><I><N><K><S><I><L><D><I><L><K><E><E><G><Y><I><K><N><Y><N><I><F><D><K><K><G><I><S><F><I><K><A><I><L><N><Y><D><N><K><R><N><P><A><I><N><R><I><D><A><I><S><T><P><G><R><K><V><Y><S><S><Y><K><N><M><P><R><I><K><N><G><Y><G><I><L><I><V><S... | One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP> | A1QZS8 |
Q32DS5 | MENH_SHIDS | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | Shigella | <M><I><L><H><A><Q><T><K><H><G><K><P><G><L><P><W><L><V><F><L><H><G><F><S><G><D><C><H><E><W><Q><E><V><G><E><V><F><A><D><Y><S><R><L><Y><V><D><L><P><G><H><G><G><S><A><A><I><S><V><D><G><F><D><D><V><T><D><L><L><R><K><T><L><V><S><Y><N><I><L><D><F><W><L><V><G><Y><S><L><G><G><R><V><A><M><M><A><A><C><Q><G><L><A><G><L><C><G><V><I... | Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).<BOP> | Q32DS5 |
A3CZA5 | MOAC_SHEB5 | Molybdenum cofactor biosynthesis protein C | Shewanella | <M><S><N><V><F><T><H><I><N><A><D><G><N><A><H><M><V><D><V><T><E><K><A><V><T><E><R><E><A><R><A><E><A><F><I><E><M><A><S><T><T><L><E><M><I><M><S><G><S><H><H><K><G><D><V><F><A><T><A><R><I><A><G><I><Q><A><A><K><K><T><S><D><L><I><P><L><C><H><P><L><M><L><T><K><V><E><V><D><L><E><A><Q><P><E><H><N><R><V><R><I><T><S><L><C><K><L><S... | Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).<BOP> | A3CZA5 |
Q8TQS4 | THII_METAC | tRNA 4-thiouridine synthase | Methanosarcina | <M><P><D><I><F><T><D><N><T><D><K><Q><D><S><D><P><S><R><Q><G><F><E><G><Q><P><N><V><V><I><V><R><Y><G><E><L><A><L><K><S><T><G><V><R><N><W><Y><E><K><I><L><M><K><N><I><A><A><M><L><D><S><R><N><I><P><Y><S><L><L><R><R><E><W><G><R><I><F><I><E><T><T><D><P><R><A><A><E><A><A><A><D><V><F><G><V><V><S><T><S><P><A><L><V><T><K><P><D><L... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | Q8TQS4 |
P14159 | HXD4_SHEEP | Homeobox protein Hox-8.1 | Ovis | <V><N><S><N><Y><T><G><G><E><P><K><R><S><R><T><A><Y><T><R><Q><Q><V><L><E><L><E><K><E><F><L><F><N><R><Y><L><T><R><R><R><R><I><Q><H><T><L><T> | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | P14159 |
A5GQ34 | IF3_SYNR3 | Translation initiation factor IF-3 | unclassified Synechococcus | <M><A><P><R><P><R><F><D><R><R><A><P><V><R><E><L><P><N><I><N><D><R><I><N><Y><P><K><L><R><V><V><D><A><D><G><T><Q><L><G><V><I><S><R><D><E><A><L><D><V><A><R><E><R><E><L><D><L><V><L><V><S><E><K><A><D><P><P><V><C><R><I><M><D><Y><G><K><F><K><F><E><Q><E><K><K><A><K><E><A><K><K><K><S><H><Q><T><E><V><K><E><V><K><M><R><Y><K><I><D... | IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.<BOP> | A5GQ34 |
D3ZTL1 | PO4F3_RAT | POU domain, class 4, transcription factor 3 | Rattus | <M><M><A><M><N><A><K><Q><P><F><G><M><H><P><V><L><Q><E><P><K><F><S><S><L><H><S><G><S><E><A><M><R><R><V><C><L><P><A><P><Q><L><Q><G><N><I><F><G><S><F><D><E><S><L><L><A><R><A><E><A><L><A><A><V><D><I><V><S><H><G><K><N><H><P><F><K><P><D><A><T><Y><H><T><M><S><S><V><P><C><T><S><T><S><P><T><V><P><I><S><H><P><A><A><L><T><S><H><P... | Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear.<BOP> | D3ZTL1 |
O42099 | MK08B_CYPCA | c-Jun N-terminal kinase B | Cyprinus | <M><N><K><N><K><R><E><K><E><F><Y><S><V><D><V><G><D><S><T><F><T><V><L><K><R><Y><Q><N><L><R><P><I><G><S><G><A><Q><G><I><V><C><S><A><Y><D><H><N><L><E><R><N><V><A><I><K><K><L><S><R><P><F><Q><N><Q><T><H><A><K><R><A><Y><R><E><L><V><L><M><K><C><V><N><H><K><N><I><I><G><L><L><N><V><F><T><P><Q><K><T><L><E><E><F><Q><D><V><Y><L><V... | Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. May play a role in the regulation of the circadian clock.<BOP> | O42099 |
Q2GXT0 | YTM1_CHAGB | Ribosome biogenesis protein YTM1 | Chaetomium | <M><D><E><P><M><V><D><A><S><G><A><Q><V><K><V><T><F><T><T><T><E><A><D><L><Q><L><P><E><S><K><R><Q><L><L><V><P><A><D><I><R><R><Y><G><L><S><R><V><L><N><S><E><S><M><L><D><T><G><S><I><P><F><D><F><L><V><N><G><S><F><L><R><T><S><L><E><D><Y><L><T><N><N><G><L><S><L><E><S><N><L><T><L><Q><Y><V><R><S><L><I><P><P><V><Y><E><A><S><F><E... | Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.<BOP> | Q2GXT0 |
B0YDW9 | FAEB1_ASPFC | Ferulic acid esterase B-1 | Aspergillus subgen. Fumigati | <M><M><W><W><F><L><L><I><G><L><A><S><A><A><A><T><A><S><S><A><S><S><A><S><F><E><S><R><C><Q><H><F><H><K><E><I><H><L><Q><N><V><H><V><L><S><T><T><Y><V><P><I><G><S><N><I><P><M><V><Y><N><P><P><I><C><G><G><T><A><S><S><S><I><S><T><I><Q><F><C><Q><V><A><L><N><V><T><T><S><D><K><S><Q><F><F><M><E><A><W><L><P><S><N><Y><T><G><R><F><L... | Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.<BOP> | B0YDW9 |
A8GPE4 | RS3_RICAH | 30S ribosomal protein S3 | spotted fever group | <M><G><Q><K><V><C><A><H><G><F><R><V><G><P><T><L><I><K><G><W><D><S><V><L><Y><A><E><K><H><Y><K><T><L><F><I><Q><D><L><K><I><R><D><L><I><N><K><G><F><N><Q><A><Q><V><S><R><V><L><I><E><R><P><S><N><K><S><I><I><I><S><I><N><A><K><K><P><N><I><I><I><G><R><N><G><S><E><I><D><K><L><K><K><A><I><E><K><M><T><F><L><K><E><V><Y><I><N><I><H... | Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.<BOP> | A8GPE4 |
Q9SV68 | QORH_ARATH | Chloroplast envelope quinone oxidoreductase homolog | Arabidopsis | <M><A><G><K><L><M><H><A><L><Q><Y><N><S><Y><G><G><G><A><A><G><L><E><H><V><Q><V><P><V><P><T><P><K><S><N><E><V><C><L><K><L><E><A><T><S><L><N><P><V><D><W><K><I><Q><K><G><M><I><R><P><F><L><P><R><K><F><P><C><I><P><A><T><D><V><A><G><E><V><V><E><V><G><S><G><V><K><N><F><K><A><G><D><K><V><V><A><V><L><S><H><L><G><G><G><G><L><A><E... | NADPH-dependent alpha,beta-unsaturated oxoene reductase reducing the double bond of medium-chain (C9) to long-chain (C18) reactive electrophile species deriving from poly-unsaturated fatty acid peroxides. The best substrates are 13-lipoxygenase-derived gamma-ketols, but is unable to reduce the double bond of short-chai... | Q9SV68 |
C0HL10 | B1OKC_NIDOK | Brevinin-1OKc | Nidirana | <F><F><G><S><I><I><G><A><L><A><K><G><L><P><S><L><I><S><L><I><K><K> | Antimicrobial peptide. Active against Gram-negative bacterium E.coli (MIC=6 uM) and against Gram-positive bacterium S.aureus (MIC=12.5 uM).<BOP> | C0HL10 |
O54423 | UREF_ACTPL | Urease accessory protein UreF | Actinobacillus | <M><G><Q><L><G><A><L><L><H><L><V><D><P><T><L><P><I><G><G><F><N><H><S><N><G><L><E><T><F><V><Q><Q><G><K><V><N><S><R><A><S><L><E><E><Y><V><Q><T><Q><L><M><Q><N><W><I><Y><N><D><G><A><Y><L><S><L><A><F><D><A><M><A><N><H><D><L><D><R><L><L><A><L><D><Q><E><L><A><A><S><K><I><A><R><E><S><R><E><G><S><Y><K><L><G><V><R><L><L><K><I><F... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | O54423 |
Q0VDE8 | ADIG_HUMAN | Adipogenin | Homo | <M><K><Y><P><L><M><P><L><V><N><D><L><T><F><S><F><L><V><F><W><F><C><L><P><V><G><L><L><L><L><L><I><I><W><L><R><F><L><L><S><Q><D><S><E><E><N><D><S><S><V><C><L><D><W><E><P><W><S><K><G><P><A><E><F><C><W><K><G><T><L><H><G><Q><E><K><E><R><P><C><W> | Plays a role in stimulating adipocyte differentiation and development.<BOP> | Q0VDE8 |
Q8R7X9 | RS13_CALS4 | 30S ribosomal protein S13 | Caldanaerobacter | <M><A><R><I><A><G><V><D><L><P><R><D><K><R><V><E><I><A><L><T><Y><I><Y><G><I><G><R><S><R><S><K><E><I><L><A><K><A><G><V><N><P><D><T><R><V><R><D><L><T><E><D><E><V><S><K><L><R><E><I><I><E><K><E><Y><K><V><E><G><D><L><R><K><E><V><A><M><N><I><K><R><L><I><D><I><G><C><Y><R><G><I><R><H><K><L><G><L><P><V><R><G><Q><R><T><R><T><N><A... | Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.<... | Q8R7X9 |
Q6B8K4 | PSBE_GRATL | PSII reaction center subunit V | Agarophyton tenuistipitatum | <M><S><G><G><S><T><G><E><R><P><F><S><D><I><I><T><S><I><R><Y><W><V><I><H><S><I><T><I><P><S><L><F><V><A><G><W><L><F><V><S><T><G><L><A><Y><D><V><F><G><T><P><R><P><N><E><Y><F><T><Q><D><R><Q><Q><V><P><L><V><N><D><R><F><S><A><K><Q><E><L><E><D><L><T><K><G><I> | This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna comp... | Q6B8K4 |
Q5R1W2 | ADH1B_PANTR | Alcohol dehydrogenase subunit beta | Pan | <M><S><T><A><G><K><V><I><K><C><K><A><A><V><L><W><E><V><K><K><P><F><S><I><E><D><V><E><V><A><P><P><K><A><Y><E><V><R><I><K><M><V><A><V><G><I><C><R><T><D><D><H><V><V><S><G><N><L><V><T><P><L><P><A><I><L><G><H><E><A><A><G><I><V><E><S><V><G><E><G><V><T><T><V><K><P><G><D><K><V><I><P><L><F><T><P><Q><C><G><K><C><R><V><C><K><N><P... | Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direc... | Q5R1W2 |
P38812 | GEP4_YEAST | PGP phosphatase GEP4 | Saccharomyces | <M><N><I><S><G><T><L><N><T><L><R><L><L><Y><N><P><S><L><C><K><P><S><L><V><V><P><T><F><N><D><L><P><I><P><I><H><D><S><I><K><A><V><V><L><D><K><D><N><C><I><A><F><P><H><D><D><K><I><W><P><D><Y><L><Q><H><W><E><T><L><R><S><K><Y><S><N><K><A><L><L><I><V><S><N><T><A><G><S><N><S><D><K><D><Y><S><Q><A><K><L><L><E><D><K><T><G><I><P><V... | Phosphatidylglycerophosphatase involved in the biosynthesis of cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes and which has important functions for cellular energy metabolism, mitochondrial dynamics and the initiation of apoptotic pathways. Required for the stabi... | P38812 |
Q9Y5I4 | PCDC2_HUMAN | Protocadherin alpha-C2 | Homo | <M><E><Q><A><G><T><R><P><A><A><T><E><H><P><R><L><R><R><P><M><P><W><L><L><L><L><P><L><L><L><L><L><L><L><L><L><P><G><P><A><A><S><Q><L><R><Y><S><V><P><E><E><Q><A><P><G><A><L><V><G><N><V><A><R><A><L><G><L><E><L><R><R><L><G><P><G><C><L><R><I><N><H><L><G><A><P><S><P><R><Y><L><E><L><D><L><T><S><G><A><L><F><V><N><E><R><I><D><R... | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.<BOP> | Q9Y5I4 |
A4F727 | THIE_SACEN | Thiamine-phosphate pyrophosphorylase | Saccharopolyspora | <M><P><G><L><D><G><F><G><I><R><A><R><L><E><E><A><L><L><Y><L><C><T><D><A><R><T><E><R><G><D><L><A><E><F><A><D><A><A><L><D><G><G><V><D><I><I><Q><L><R><D><K><S><A><G><G><A><P><L><E><A><R><H><E><L><A><A><L><E><V><L><A><E><A><C><V><R><H><G><A><L><L><A><V><N><D><R><A><D><V><A><M><A><A><D><A><D><V><L><H><L><G><Q><D><D><L><P><V... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | A4F727 |
Q7T2Q4 | PA2A2_BUNFL | Phosphatidylcholine 2-acylhydrolase | Bungarus | <M><N><P><A><H><L><L><V><L><S><A><V><C><V><S><L><L><G><A><A><I><V><P><P><Q><P><L><N><L><I><Q><F><S><S><L><I><Q><C><A><N><G><G><S><R><A><T><W><H><Y><A><D><Y><G><C><Y><C><G><K><G><G><G><G><T><P><V><D><E><L><D><R><C><C><Q><T><H><D><N><C><Y><G><E><A><E><K><L><T><K><C><S><P><Y><Y><K><T><Y><K><Y><D><C><S><E><G><K><L><T><C><N... | PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<BOP> | Q7T2Q4 |
A6TRL1 | RIMP_ALKMQ | Ribosome maturation factor RimP | Alkaliphilus | <M><N><K><I><E><S><I><T><E><D><L><I><T><P><I><V><E><A><E><Q><F><E><L><V><D><I><E><F><K><K><E><G><P><H><K><Y><L><R><V><Y><I><D><K><P><G><G><I><T><L><D><D><C><Q><K><V><S><E><G><L><S><K><K><L><D><E><A><D><P><I><V><E><N><Y><F><L><E><V><S><S><P><G><L><D><R><P><L><K><R><E><V><D><F><L><K><F><K><G><E><M><I><E><L><K><L><Y><E><A... | Required for maturation of 30S ribosomal subunits.<BOP> | A6TRL1 |
Q4IBL8 | DML1_GIBZE | Protein DML1 | Fusarium | <M><R><E><I><V><T><L><Q><L><D><Q><E><S><Y><F><T><Y><S><S><D><E><K><S><L><I><D><H><N><V><H><W><R><A><G><L><G><A><D><G><S><E><T><F><L><P><R><T><V><I><Y><D><L><K><G><G><F><G><S><L><R><K><I><N><A><L><Y><E><A><E><S><E><S><A><P><E><A><L><W><S><G><Q><S><V><V><H><K><Q><T><P><I><T><P><S><E><Y><Q><Q><S><L><D><A><G><S><E><P><A><Q... | Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.<BOP> | Q4IBL8 |
G3XDT7 | LYSC_DRONO | 1,4-beta-N-acetylmuramidase C | Dromaius | <M><K><F><F><L><I><L><G><F><C><L><L><P><L><I><A><Q><G><K><V><F><Q><R><C><E><L><A><A><A><M><K><K><H><G><L><S><N><Y><R><G><Y><S><L><G><H><W><V><C><A><A><K><Y><E><S><N><F><N><T><A><A><I><N><R><N><R><D><G><S><S><D><Y><G><I><L><Q><I><N><S><R><W><W><C><N><D><G><R><T><S><G><A><K><N><L><C><K><I><S><C><S><A><L><L><S><S><D><I><T... | Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<BOP> | G3XDT7 |
Q9RKY0 | RBPA_STRCO | RNA polymerase-binding protein RbpA | Streptomyces albidoflavus group | <M><S><E><R><A><L><R><G><T><R><L><V><V><T><S><Y><E><T><D><R><G><I><D><L><A><P><R><Q><A><V><E><Y><A><C><E><K><G><H><R><F><E><M><P><F><S><V><E><A><E><I><P><P><E><W><E><C><K><V><C><G><A><Q><A><L><L><V><D><G><D><G><P><E><E><K><K><A><K><P><A><R><T><H><W><D><M><L><M><E><R><R><T><R><E><E><L><E><E><V><L><E><E><R><L><A><V><L><R... | Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation in... | Q9RKY0 |
Q2NEH8 | GCH3_METST | GTP cyclohydrolase III | Methanosphaera | <M><I><Q><V><T><L><I><Q><I><D><N><Y><G><P><W><T><V><T><P><G><P><R><A><E><P><D><L><Q><T><L><Q><S><R><L><Y><G><D><L><E><R><E><F><G><A><H><G><A><I><V><F><F><N><R><F><D><N><L><I><A><I><S><N><G><M><D><Y><D><D><H><L><L><I><Q><Q><S><I><R><N><R><Y><P><I><T><I><S><M><G><V><G><T><A><D><T><A><Y><E><A><Q><K><I><A><T><K><M><I><Q><N... | Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.<BOP> | Q2NEH8 |
Q6HC18 | GLGA_BACHK | Starch [bacterial glycogen] synthase | Bacillus cereus group | <M><N><I><L><F><A><V><S><E><C><V><P><F><V><K><S><G><G><L><A><D><V><A><G><A><L><P><K><E><L><K><K><L><G><V><E><V><R><I><I><L><P><N><Y><S><L><I><P><Q><K><L><R><D><G><C><T><L><H><K><V><I><N><V><P><L><G><W><R><N><Q><Y><C><G><I><L><K><G><E><Q><D><G><I><T><Y><Y><L><I><D><N><E><Y><Y><F><K><R><D><S><L><Y><G><H><Y><D><D><G><E><R... | Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP> | Q6HC18 |
A9ISF8 | RL7_BART1 | 50S ribosomal protein L7/L12 | Bartonella | <M><A><D><L><A><K><I><V><E><D><L><S><N><L><T><L><L><E><A><A><E><L><S><K><L><L><E><E><K><W><G><V><S><A><A><A><P><V><A><V><A><A><V><A><G><A><A><A><P><A><A><E><E><K><T><E><F><D><V><I><L><V><E><G><G><A><Q><K><I><N><V><I><K><E><V><R><A><L><T><G><L><G><L><K><E><A><K><D><L><V><E><G><A><P><K><P><I><K><E><G><A><S><K><E><E><A><E... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP> | A9ISF8 |
Q7M803 | ACPS_WOLSU | 4'-phosphopantetheinyl transferase AcpS | Wolinella | <M><I><G><I><D><L><V><S><I><E><R><I><E><A><F><I><A><K><H><G><Q><R><G><L><E><R><F><L><L><P><E><E><I><L><L><A><N><K><P><E><T><I><A><G><F><W><A><A><K><E><A><C><S><K><A><L><G><T><G><I><G><A><E><V><G><F><H><D><I><R><L><F><K><N><P><K><G><A><P><L><L><E><L><S><P><R><V><K><D><R><F><E><I><D><S><C><A><L><S><I><T><H><D><K><G><F><A... | Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP> | Q7M803 |
C0HK11 | CZS15_CRUCA | Cruzioseptin-15 | Cruziohyla | <G><F><L><D><I><V><K><G><V><G><L><V><A><L><G><A><V><S><K><S> | Has antimicrobial activity.<BOP> | C0HK11 |
C7J6G6 | AB46G_ORYSJ | Pleiotropic drug resistance protein 21 | Oryza sativa | <M><D><D><D><V><D><A><G><E><I><Y><A><V><D><R><Q><R><E><E><G><S><A><S><A><A><A><F><S><R><S><P><S><T><G><R><V><D><D><D><D><D><D><L><L><T><Y><G><R><S><A><R><R><M><A><A><L><P><A><P><A><M><P><E><G><T><E><L><R><R><P><V><G><G><D><V><V><G><D><D><D><Y><L><R><F><L><Y><K><F><K><E><L><F><D><R><V><G><I><K><L><P><T><I><E><V><R><Y><K... | May be a general defense protein.<BOP> | C7J6G6 |
B4S010 | RL9_ALTMD | 50S ribosomal protein L9 | Alteromonas | <M><N><I><I><L><L><D><K><I><A><N><L><G><G><L><G><D><Q><V><T><V><K><S><G><Y><A><R><N><F><L><F><P><Q><G><K><A><V><P><A><T><K><D><N><V><E><K><F><E><A><R><R><A><E><L><E><A><K><I><A><E><Q><L><A><A><A><N><A><R><A><E><K><V><A><E><L><A><E><V><T><I><A><A><P><A><G><D><E><G><K><L><F><G><S><V><G><T><R><D><I><A><D><A><I><T><A><A><G... | Binds to the 23S rRNA.<BOP> | B4S010 |
P83041 | DID5_CERCE | Disintegrin CC5B | Cerastes | <M><N><S><A><H><P><C><C><D><P><V><T><C><K><P><K><R><G><E><H><C><I><S><G><P><C><C><R><N><C><K><F><L><S><P><G><T><I><C><K><K><A><R><G><D><D><M><N><D><Y><C><T><G><I><S><S><D><C><P><R><N><R><Y><K><S> | Binds and inhibits integrins alpha-IIb/beta-3 (ITGA2B/ITGB3), alpha-V/beta-3 (ITGAV/ITGB3) and alpha-5/beta-1 (ITGA5/ITGB1).<BOP> | P83041 |
Q5VVX9 | UBE2U_HUMAN | Ubiquitin-protein ligase U | Homo | <M><H><G><R><A><Y><L><L><L><H><R><D><F><C><D><L><K><E><N><N><Y><K><G><I><T><A><K><P><V><S><E><D><M><M><E><W><E><V><E><I><E><G><L><Q><N><S><V><W><Q><G><L><V><F><Q><L><T><I><H><F><T><S><E><Y><N><Y><A><P><P><V><V><K><F><I><T><I><P><F><H><P><N><V><D><P><H><T><G><Q><P><C><I><D><F><L><D><N><P><E><K><W><N><T><N><Y><T><L><S><S... | Catalyzes the covalent attachment of ubiquitin to other proteins.<BOP> | Q5VVX9 |
O65862 | CAMT1_POPTR | Trans-caffeoyl-CoA 3-O-methyltransferase 1 | Populus | <M><A><T><N><G><E><E><Q><Q><S><Q><A><G><R><H><Q><E><V><G><H><K><S><L><L><Q><S><D><A><L><Y><Q><Y><I><L><E><T><S><V><Y><P><R><E><P><E><C><M><K><E><L><R><E><V><T><A><K><H><P><W><N><I><M><T><T><S><A><D><E><G><Q><F><L><N><M><L><L><K><L><V><N><A><K><N><T><M><E><I><G><V><Y><T><G><Y><S><L><L><A><T><A><L><A><I><P><E><D><G><K><I... | Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic ... | O65862 |
X5JB51 | SECAB_ARATH | Exocyst complex component SEC10b | Arabidopsis | <M><T><E><R><I><R><A><R><G><P><R><S><S><S><V><N><S><V><P><L><I><L><D><I><E><D><F><K><G><D><F><S><F><D><A><L><F><G><N><L><V><N><D><L><L><P><S><F><L><D><E><E><A><D><S><G><D><G><H><G><N><I><A><G><V><D><G><L><T><N><G><H><L><R><G><Q><S><A><P><L><S><S><A><P><F><F><P><E><V><D><G><L><L><S><L><F><K><D><A><C><K><E><L><V><D><L><R... | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new pri... | X5JB51 |
B8EE60 | CYSD_SHEB2 | Sulfate adenylate transferase | Shewanella | <M><A><G><R><E><L><S><H><L><Q><Q><L><E><A><E><S><I><Q><I><I><R><E><V><A><A><E><F><D><N><P><V><M><L><Y><S><I><G><K><D><S><S><V><M><L><H><L><A><R><K><A><F><Y><P><G><K><I><P><F><P><L><L><H><V><D><T><G><W><K><F><K><E><M><I><A><F><R><D><A><Q><A><K><K><F><G><F><E><L><L><T><H><I><N><P><E><G><L><A><Q><G><I><N><P><F><D><H><G><S... | With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi... | B8EE60 |
A6L1V8 | LEUC_PHOV8 | Isopropylmalate isomerase | Phocaeicola | <M><A><N><T><L><F><D><K><I><W><D><A><H><V><V><Q><K><V><E><E><G><P><T><Q><L><Y><I><D><R><L><Y><C><H><E><V><T><S><P><Q><A><F><A><G><L><R><A><R><G><V><K><V><F><R><P><D><H><V><Y><C><M><P><D><H><N><T><P><T><H><D><Q><D><K><P><I><E><D><P><V><S><K><T><Q><V><D><T><L><A><K><N><A><K><D><F><G><L><A><H><F><G><M><M><D><K><R><N><G><I... | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP> | A6L1V8 |
Q8R3Q2 | PP6R2_MOUSE | SAPS domain family member 2 | Mus | <M><F><W><K><F><D><L><N><T><T><S><H><V><D><K><L><L><D><K><E><H><V><T><L><Q><E><L><M><D><E><D><D><I><L><Q><E><C><K><A><Q><N><Q><K><L><L><D><F><L><C><R><Q><Q><C><M><E><E><L><V><N><L><I><T><Q><D><P><P><Q><D><M><E><E><K><V><R><F><K><Y><P><N><T><A><C><E><L><L><T><C><D><V><P><Q><I><S><D><R><L><G><E><D><E><S><L><L><N><L><L><Y... | Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.<BOP> | Q8R3Q2 |
Q2YXP5 | TRUB_STAAB | tRNA-uridine isomerase | Staphylococcus | <M><Y><N><G><I><L><P><V><Y><K><E><R><G><L><T><S><H><D><V><V><F><K><L><R><K><I><L><K><T><K><K><I><G><H><T><G><T><L><D><P><E><V><A><G><V><L><P><V><C><I><G><N><A><T><R><V><S><D><Y><V><M><D><M><G><K><A><Y><E><A><N><V><S><I><G><R><S><T><T><T><E><D><Q><T><G><D><T><L><E><M><K><G><V><H><S><A><D><F><N><N><D><D><I><D><R><L><L><E... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | Q2YXP5 |
Q2NHD9 | IF2B_METST | eIF-2-beta | Methanosphaera | <M><A><K><E><N><A><E><F><K><E><Y><E><K><L><L><D><Q><A><Y><E><Q><L><P><D><K><I><F><E><A><K><R><F><K><V><P><K><G><Y><S><V><I><Q><G><N><R><T><I><I><K><N><F><G><D><V><S><R><T><L><N><R><D><P><Q><H><V><L><K><Y><L><L><R><E><L><G><T><S><G><N><V><E><G><N><R><A><I><L><Q><G><K><F><T><H><Y><V><I><N><D><R><V><K><E><Y><V><D><N><F><V... | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.<BOP> | Q2NHD9 |
Q46GA1 | RS3_METBF | 30S ribosomal protein S3 | Methanosarcina | <M><A><I><E><R><K><F><V><N><D><G><F><V><K><A><S><M><D><E><Y><F><A><E><Q><L><N><R><A><G><Y><G><G><M><E><L><N><R><T><P><M><G><T><Q><I><V><I><Y><S><E><K><P><G><M><V><I><G><K><A><G><K><V><I><R><K><L><T><R><D><V><A><A><R><Y><N><L><E><N><P><Q><I><D><A><Q><E><V><K><K><P><E><L><N><A><Q><M><M><A><S><R><L><A><A><S><I><E><R><G><W... | Binds the lower part of the 30S subunit head.<BOP> | Q46GA1 |
Q8FS54 | RL6_COREF | 50S ribosomal protein L6 | Corynebacterium | <M><S><R><I><G><K><N><P><I><A><I><P><S><G><V><E><V><K><I><D><G><R><L><V><D><V><K><G><P><K><G><N><L><N><V><T><L><P><E><P><I><T><A><S><I><E><N><N><E><I><L><V><T><R><P><D><D><H><R><N><S><R><S><M><H><G><L><S><R><S><L><V><N><N><L><V><V><G><V><T><E><G><Y><T><I><K><M><E><I><F><G><V><G><Y><R><V><A><L><K><G><K><N><L><E><F><S><L... | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP> | Q8FS54 |
Q9KGE8 | SECE_HALH5 | Protein translocase subunit SecE | Halalkalibacterium (ex Joshi et al. 2022) | <M><A><G><G><V><K><G><I><G><K><F><F><G><D><V><V><A><E><M><K><R><V><S><W><P><T><R><K><E><L><T><R><Y><T><L><V><V><L><G><T><V><A><F><I><T><V><F><F><A><V><V><D><Y><G><I><S><A><L><V><R><G><L><I><E> | Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.<BOP> | Q9KGE8 |
Q4G3C6 | PSBZ_EMIHU | Photosystem II reaction center protein Z | Emiliania | <M><V><G><I><L><P><L><F><V><V><L><L><I><I><V><S><F><A><M><V><V><A><V><P><V><I><L><A><T><P><G><E><W><E><K><S><Q><G><I><V><W><S><G><A><G><L><W><S><A><L><V><I><L><T><G><V><F><N><A><V><P><A> | Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.<BOP> | Q4G3C6 |
Q9SLK2 | ALIS3_ARATH | ALA-interacting subunit 3 | Arabidopsis | <M><S><S><N><T><A><S><S><S><A><G><A><A><G><S><G><D><S><S><A><A><R><K><N><S><K><R><P><K><Y><S><K><F><T><Q><Q><E><L><P><A><C><K><P><I><L><T><P><G><W><V><I><S><T><F><L><I><V><S><V><I><F><I><P><L><G><V><I><S><L><F><A><S><Q><D><V><V><E><I><V><D><R><Y><D><T><E><C><I><P><A><P><A><R><T><N><K><V><A><Y><I><Q><G><D><G><D><K><V><C... | Required for the lipid transport activity of the ALA/ALIS P4-ATPase complex.<BOP> | Q9SLK2 |
B2VK80 | RL18_ERWT9 | 50S ribosomal protein L18 | Erwinia | <M><D><K><K><S><A><R><I><R><R><A><T><R><A><R><R><K><L><K><E><L><G><A><T><R><L><V><V><H><R><T><P><R><H><I><Y><A><Q><V><I><A><P><N><G><S><E><V><L><V><A><A><S><T><V><E><K><A><I><G><E><Q><L><K><Y><T><G><N><K><D><A><A><A><A><V><G><K><A><V><A><E><R><A><I><E><K><G><I><T><G><V><S><F><D><R><S><G><F><Q><Y><H><G><R><V><Q><A><L><A... | This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP> | B2VK80 |
A9WFA3 | CH602_CHLAA | Chaperonin-60 2 | Chloroflexus | <M><A><K><Q><L><I><F><D><Q><Q><A><R><T><A><L><K><H><G><I><D><T><L><A><L><A><V><K><T><T><L><G><P><R><G><R><N><V><A><L><D><K><K><W><G><A><P><T><V><T><H><D><G><V><S><V><A><K><E><I><E><L><K><D><P><F><A><N><L><G><V><Q><L><L><K><Q><A><A><V><K><T><N><D><V><A><G><D><G><T><T><T><A><T><V><L><A><Q><A><I><I><N><E><G><L><K><L><V><A... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | A9WFA3 |
P06149 | DLD_ECOLI | Respiratory D-lactate dehydrogenase | Escherichia | <M><S><S><M><T><T><T><D><N><K><A><F><L><N><E><L><A><R><L><V><G><S><S><H><L><L><T><D><P><A><K><T><A><R><Y><R><K><G><F><R><S><G><Q><G><D><A><L><A><V><V><F><P><G><S><L><L><E><L><W><R><V><L><K><A><C><V><T><A><D><K><I><I><L><M><Q><A><A><N><T><G><L><T><E><G><S><T><P><N><G><N><D><Y><D><R><D><V><V><I><I><S><T><L><R><L><D><K><L... | Catalyzes the oxidation of D-lactate to pyruvate. Electrons derived from D-lactate oxidation are transferred to the ubiquinone/cytochrome electron transfer chain, where they may be used to provide energy for the active transport of a variety of amino acids and sugars across the membrane.<BOP> | P06149 |
Q07IE7 | ILVD_RHOP5 | Dihydroxy-acid dehydratase | Rhodopseudomonas | <M><P><A><Y><R><S><R><T><S><T><H><G><R><N><M><A><G><A><R><S><L><W><R><A><T><G><M><K><N><E><D><F><G><K><P><I><I><A><V><V><N><S><F><T><Q><F><V><P><G><H><V><H><L><K><D><L><G><Q><L><V><A><R><E><I><E><K><A><G><G><I><A><K><E><F><N><T><I><A><I><D><D><G><I><A><M><G><H><D><G><M><L><Y><S><L><P><S><R><E><L><I><A><D><S><V><E><Y><M... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | Q07IE7 |
A1JIM8 | TDCC_YERE8 | H(+)/threonine-serine symporter | Yersinia | <M><H><I><D><N><A><I><T><T><T><I><E><T><K><T><W><R><K><S><D><T><T><W><T><L><G><L><F><G><T><A><I><G><A><G><V><L><F><F><P><I><R><A><G><F><G><G><L><I><P><I><L><I><M><L><V><L><A><Y><P><I><A><F><L><C><H><R><A><L><A><R><L><C><L><S><G><S><N><C><S><G><N><I><T><E><T><V><E><E><H><F><G><K><T><G><G><V><V><I><T><F><L><Y><F><F><A><I... | Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).<BOP> | A1JIM8 |
A3N1M8 | IF1_ACTP2 | Translation initiation factor IF-1 | Actinobacillus | <M><A><K><E><D><C><I><E><M><Q><G><T><I><L><E><T><L><P><N><T><M><F><R><V><E><L><E><N><G><H><V><V><T><A><H><I><S><G><K><M><R><K><N><Y><I><R><I><L><T><G><D><K><V><T><V><E><M><T><P><Y><D><L><S><K><A><R><I><I><F><R><A><R> | One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-... | A3N1M8 |
P37738 | FATD_VIBA7 | Ferric-anguibactin transport system permease protein FatD | Vibrio | <M><T><F><R><M><I><L><A><F><F><T><L><C><A><T><S><L><F><F><G><A><N><Q><I><E><W><S><L><L><P><T><F><N><E><K><A><W><L><P><I><I><A><S><R><L><P><R><L><V><A><L><I><L><T><G><S><G><L><A><M><C><G><V><I><L><Q><H><I><V><R><N><R><F><V><E><P><G><T><T><G><S><L><D><A><A><K><L><G><I><L><V><S><I><V><M><L><P><S><S><D><K><L><E><R><M><F><F... | Involved in the uptake of iron in complex with the siderophore anguibactin. Responsible for the translocation of ferric-anguibactin across the cytoplasmic membrane.<BOP> | P37738 |
O74368 | MMM1_SCHPO | Maintenance of mitochondrial morphology protein 1 | Schizosaccharomyces | <M><I><H><L><P><Q><G><S><F><T><Q><G><L><I><V><G><Q><L><L><T><L><A><I><I><Y><V><F><L><R><F><F><L><F><C><S><P><I><P><K><S><V><A><N><S><P><K><Q><T><G><N><E><T><P><D><E><T><P><S><T><P><L><S><N><N><K><K><R><Y><K><K><P><L><T><I><L><E><P><H><I><L><N><L><L><Y><D><V><N><E><H><E><P><E><S><L><D><W><F><N><V><L><I><A><Q><A><L><I><Q... | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm... | O74368 |
P29987 | PYG2_NOSS1 | L-RC 28.5 | Nostoc | <M><S><I><P><L><L><E><Y><K><P><S><S><Q><N><Q><R><V><P><G><Y><E><V><P><N><E><D><T><P><R><I><Y><R><I><E><D><A><A><Y><D><S><E><L><K><E><L><I><W><A><T><Y><R><Q><V><F><S><E><H><V><I><L><K><F><F><R><Q><G><N><L><E><S><Q><L><K><N><R><A><I><S><V><R><D><F><V><R><G><L><A><K><S><E><A><F><K><T><L><V><I><K><S><N><S><N><Y><R><L><V><E... | Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.<BOP> | P29987 |
Q1GUG9 | GREA_SPHAL | Transcript cleavage factor GreA | Sphingopyxis | <M><A><S><V><E><K><V><P><M><L><A><E><G><Y><E><K><L><T><A><Q><L><A><A><L><K><A><E><R><P><L><I><V><D><A><I><E><E><A><R><A><H><G><D><L><S><E><N><A><E><Y><H><A><A><K><E><R><Q><G><Q><V><E><A><T><I><G><D><L><E><D><K><L><S><R><A><Q><V><I><D><P><T><T><L><S><G><D><R><I><V><F><G><A><T><V><T><L><T><D><E><D><D><K><P><V><K><Y><Q><I... | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor... | Q1GUG9 |
B4K4M0 | HH_DROMO | Protein hedgehog N-product | Drosophila | <M><D><N><N><Q><A><V><S><A><L><W><S><C><A><S><A><T><C><L><S><L><D><A><K><R><H><S><L><E><P><S><S><P><D><G><Q><A><S><L><D><V><N><N><K><S><A><P><V><D><A><H><A><R><K><L><R><H><I><A><H><T><P><R><G><S><C><F><M><A><L><L><L><L><L><L><L><A><L><N><F><R><H><A><H><S><C><G><P><G><R><G><L><G><R><R><R><E><R><N><L><Y><P><L><V><L><K><Q... | The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks. Binds to the patched (ptc) receptor, which functions in association with smoo... | B4K4M0 |
Q60AI1 | POTA_METCA | Spermidine/putrescine import ATP-binding protein PotA | Methylococcus | <M><R><P><S><R><R><P><R><F><R><N><I><L><E><N><R><T><I><A><A><M><T><R><S><T><I><A><S><F><R><A><V><S><K><H><Y><G><S><H><C><A><L><R><D><F><N><L><E><L><R><E><G><E><L><L><T><L><L><G><P><S><G><C><G><K><T><T><V><L><R><L><L><A><G><L><E><I><P><D><S><G><E><I><F><L><D><G><R><T><L><A><G><V><P><P><E><A><R><N><V><N><T><V><F><Q><S><Y... | Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.<BOP> | Q60AI1 |
Q43594 | TBB1_ORYSJ | Beta-1-tubulin | Oryza sativa | <M><R><E><I><L><H><I><Q><G><G><Q><C><G><N><Q><I><G><S><K><F><W><E><V><V><C><D><E><H><G><I><D><P><T><G><R><Y><V><G><T><S><D><L><Q><L><E><R><V><N><V><Y><Y><N><E><A><S><C><G><R><F><V><P><R><A><V><L><M><D><L><E><P><G><T><M><D><S><V><R><T><G><P><Y><G><Q><I><F><R><P><D><N><F><V><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | Q43594 |
Q5MIM5 | RK31_PALPL | 50S ribosomal protein L31, chloroplastic | Palmaria | <M><P><Q><I><D><I><H><P><E><W><Y><N><D><S><K><V><Y><C><D><G><K><H><I><M><T><I><G><S><T><K><P><E><L><H><V><D><I><W><S><G><N><H><P><F><F><T><G><S><Q><R><I><I><D><T><E><G><R><V><E><R><F><M><R><K><Y><N><V><Q><K><T><A><D><T> | Binds the 23S rRNA.<BOP> | Q5MIM5 |
Q8K4I6 | CBY1_RAT | PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 | Rattus | <M><P><L><F><G><S><I><F><S><P><K><K><T><P><P><R><K><S><A><S><L><S><N><L><H><S><L><D><R><S><T><R><E><L><E><L><G><L><D><Y><G><T><P><T><M><N><L><A><G><Q><S><L><K><F><E><N><G><Q><W><V><A><D><S><V><I><S><G><G><V><D><R><R><E><T><Q><R><L><R><K><R><N><Q><Q><L><E><E><E><N><N><L><L><R><L><K><V><D><I><L><L><D><M><L><S><E><T><T><A... | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellu... | Q8K4I6 |
Q32CN1 | SYA_SHIDS | Alanyl-tRNA synthetase | Shigella | <M><S><K><S><T><A><E><I><R><Q><A><F><L><D><F><F><H><S><K><G><H><Q><V><V><A><S><S><S><L><V><P><H><N><D><P><T><L><L><F><T><N><A><G><M><N><Q><F><K><D><V><F><L><G><L><D><K><R><N><Y><S><R><A><T><T><S><Q><R><C><V><R><A><G><G><K><H><N><D><L><E><N><V><G><Y><T><A><R><H><H><T><F><F><E><M><L><G><N><F><S><F><G><D><Y><F><K><H><D><A... | Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP> | Q32CN1 |
Q7UWC8 | ISPG_RHOBA | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase | Rhodopirellula | <M><L><S><F><M><K><I><R><R><N><P><T><R><P><V><T><I><G><S><I><T><I><G><D><G><H><P><I><A><V><Q><S><M><T><A><T><K><T><Q><N><I><D><A><T><V><E><Q><A><E><A><L><H><A><R><G><A><G><V><V><R><I><A><V><D><S><D><K><D><A><E><A><L><A><E><I><R><K><Q><T><Q><A><N><L><A><V><D><L><Q><E><N><F><R><L><A><E><K><V><A><P><H><V><D><K><I><R><Y><N... | Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.<BOP> | Q7UWC8 |
Q9N4D9 | NTM1_CAEEL | X-Pro-Lys N-terminal protein methyltransferase 1 | Caenorhabditis | <M><S><S><S><S><S><S><R><I><H><N><G><E><D><V><Y><E><K><A><E><E><Y><W><S><R><A><S><Q><D><V><N><G><M><L><G><G><F><E><A><L><H><A><P><D><I><S><A><S><K><R><F><I><E><G><L><K><K><K><N><L><F><G><Y><F><D><Y><A><L><D><C><G><A><G><I><G><R><V><T><K><H><L><L><M><P><F><F><S><K><V><D><M><E><D><V><V><E><E><L><I><T><K><S><D><Q><Y><I><G... | Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-meth... | Q9N4D9 |
Q5T753 | LCE1E_HUMAN | Late envelope protein 5 | Homo | <M><S><C><Q><Q><S><Q><Q><Q><C><Q><P><P><P><K><C><T><P><K><C><P><P><K><C><P><T><P><K><C><P><P><K><C><P><P><K><C><P><P><V><S><S><C><C><S><V><S><S><G><G><C><C><G><S><S><S><G><G><S><C><G><S><S><S><G><G><C><C><S><S><G><G><G><G><C><C><L><S><H><H><R><H><H><R><S><H><R><H><R><P><Q><S><S><D><C><C><S><Q><P><S><G><G><S><S><C><C><G... | Precursors of the cornified envelope of the stratum corneum.<BOP> | Q5T753 |
A9QCA0 | CCSA_TRACE | Cytochrome c biogenesis protein CcsA | Trachelium | <M><K><F><S><T><L><E><H><I><L><I><H><L><S><F><S><I><C><S><I><V><I><T><I><R><L><I><N><L><V><V><T><T><I><L><K><P><Y><D><F><S><E><K><G><I><I><T><T><F><L><C><L><T><G><F><L><V><T><R><W><I><Y><S><G><H><F><P><L><S><N><L><Y><E><S><L><I><F><L><S><W><S><F><S><L><I><H><I><V><A><Y><L><K><K><N><K><N><L><S><R><I><T><A><S><S><T><I><F... | Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.<BOP> | A9QCA0 |
Q6G1Z7 | EFP_BARHE | Elongation factor P | Bartonella | <M><K><I><N><G><N><E><I><R><P><G><N><V><I><E><H><Q><G><S><L><W><V><A><V><K><C><N><A><V><K><P><G><K><G><G><A><F><N><Q><V><E><M><K><N><L><I><D><G><T><K><L><N><E><R><F><R><A><A><E><T><V><E><R><V><R><L><E><Q><K><D><F><T><F><L><Y><Q><Q><G><D><A><L><I><F><M><D><S><Q><S><Y><E><Q><L><E><L><Q><K><D><F><V><G><E><R><A><A><F><L><Q... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | Q6G1Z7 |
P22005 | PENK_MOUSE | Met-enkephalin-Arg-Phe | Mus | <M><A><R><F><L><R><L><C><T><W><L><L><A><L><G><S><C><L><L><A><T><V><Q><A><E><C><S><Q><D><C><A><K><C><S><Y><R><L><V><R><P><G><D><I><N><F><L><A><C><T><L><E><C><E><G><Q><L><P><S><F><K><I><W><E><T><C><K><D><L><L><Q><V><S><R><P><E><F><P><W><D><N><I><D><M><Y><K><D><S><S><K><Q><D><E><S><H><L><L><A><K><K><Y><G><G><F><M><K><R><Y... | Increases glutamate release in the striatum.<BOP> | P22005 |
B0R2R5 | NIKR_HALS3 | Putative nickel-responsive regulator | Halobacterium | <M><S><V><V><S><V><S><M><P><E><E><L><L><E><R><L><D><D><F><A><D><D><H><G><Y><T><G><R><S><E><V><V><R><E><A><S><R><N><L><L><G><E><F><E><D><K><K><L><E><G><R><E><L><M><G><V><V><T><V><V><F><D><Y><E><T><T><T><V><E><E><K><M><M><H><L><R><H><E><H><E><G><L><V><A><S><N><F><H><S><H><V><G><G><H><H><C><M><E><L><F><V><L><E><G><S><L><E... | Transcriptional regulator.<BOP> | B0R2R5 |
Q8DA38 | PNCB_VIBVU | Nicotinate phosphoribosyltransferase | Vibrio | <M><C><A><P><L><F><Q><P><A><I><I><Q><S><V><L><D><L><D><V><Y><K><I><N><M><M><Q><A><A><Y><R><F><Y><P><Q><T><Q><V><R><Y><E><L><I><V><R><S><D><D><N><L><S><D><L><V><E><E><V><R><E><E><I><N><R><L><A><E><L><R><F><D><A><A><Q><L><A><Y><L><A><E><K><A><P><Y><L><T><A><E><F><L><S><Y><L><E><T><F><R><F><H><P><Q><Q><Q><V><S><V><G><I><F... | Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.<BOP> | Q8DA38 |
P47292 | TSAD_MYCGE | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Mycoplasma | <M><E><Q><P><L><C><V><L><G><I><E><T><T><C><D><D><T><G><L><S><I><V><I><D><Q><K><I><K><S><N><I><V><I><S><S><A><N><L><H><V><K><T><G><G><V><V><P><E><I><A><A><R><C><H><E><Q><N><L><F><K><A><I><R><D><L><N><F><E><I><R><D><L><S><H><I><A><Y><A><C><N><P><G><L><A><G><C><L><H><V><G><A><T><F><A><R><S><L><S><F><L><L><D><K><P><L><L><P... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | P47292 |
P19972 | TOXK_MILFA | Salt-mediated killer toxin 1 beta chain | Millerozyma | <M><R><K><E><T><L><I><G><L><A><F><I><T><A><N><V><I><A><W><S><L><R><W><R><M><Q><K><S><T><T><I><A><A><I><A><G><C><S><G><A><A><T><F><G><G><L><A><G><G><I><V><G><C><I><A><A><G><I><L><A><I><L><Q><G><F><E><V><N><W><H><N><G><G><G><G><D><R><S><N><P><V><K><R><S><S><D><S><F><S><I><V><N><H><N><G><E><K><V><D><S><Y><A><H><L><V><P><G... | This toxin kills sensitive strains of yeast.<BOP> | P19972 |
Q4FPA9 | SYI_PELUB | Isoleucyl-tRNA synthetase | Candidatus Pelagibacter | <M><S><K><E><N><I><N><L><P><K><T><A><F><S><M><K><A><N><L><Q><N><K><E><P><E><I><L><E><Y><W><K><K><I><D><L><Y><K><E><L><R><K><S><N><K><G><K><E><K><F><I><L><H><D><G><P><P><Y><A><N><G><N><I><H><M><G><T><A><L><N><K><I><L><K><D><I><I><V><K><F><H><Q><M><D><G><K><D><S><V><Y><V><P><G><W><D><C><H><G><L><P><I><E><W><K><I><E><E><Q... | Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrol... | Q4FPA9 |
P34619 | SOR1_CAEEL | Sop-2-related protein 1 | Caenorhabditis | <M><T><I><N><I><K><Y><S><S><K><F><S><S><S><K><T><S><S><S><E><E><L><K><P><K><T><Y><I><P><A><Y><Y><Q><P><P><V><S><M><P><K><Y><Y><V><N><W><L><R><I><K><L><S><L><N><K><L><K><N><I><R><A><I><Y><L><F><D><Q><C><Q><N><F><N><Q><Y><Q><E><S><S><R><K><F><S><A><G><Q><V><S><S><L><T><P><W><Y><S><N><F><S><N><Y><S><T><V><I><L><R><M><K><D... | Acts synergistically with sop-2 to maintain the transcriptionally repressive state of homeotic genes throughout development. Not required to initiate repression, but to maintain it during later stages of development. Also required to repress expression of other genes. Binds RNA in a sequence-independent manner.<BOP> | P34619 |
Q479B1 | DADA_DECAR | D-amino acid dehydrogenase | Dechloromonas | <M><R><V><L><V><L><G><A><G><V><V><G><T><T><S><A><W><Y><L><A><R><A><G><H><Q><V><T><V><V><D><R><Q><P><V><A><G><N><E><T><S><F><A><N><G><G><Q><I><S><V><S><H><A><E><P><W><A><N><P><H><V><L><P><R><V><L><K><W><L><G><R><E><D><A><P><L><L><W><R><W><R><A><D><P><A><Q><L><A><W><G><L><R><F><L><G><E><C><F><P><G><R><V><R><R><N><I><A><A... | Oxidative deamination of D-amino acids.<BOP> | Q479B1 |
C0HJJ7 | TX1A_GRAIH | GiTx1 | Grammostola | <S><C><Q><K><W><M><W><T><C><D><Q><K><R><P><C><C><E><D><M><V><C><K><L><W><C><K><I><I><K> | Inhibits mammalian and insect voltage-gated sodium and potassium voltage-gated channels. Inhibits the mammalian sodium channels rNav1.2/SCN2A, rNav1.3/SCN3A, rNav1.4/SCN4A, hNav1.5/SCN5A, mNav1.6/SCN8A (IC(50)=156.39 nM), hNav1.8/SCN10A, the arachnid sodium channel VdNav (IC(50)=124.05 nM), as well as the potassium cha... | C0HJJ7 |
A4JCW1 | ASTB_BURVG | N-succinylarginine dihydrolase | Burkholderia cepacia complex | <M><N><A><Q><E><A><N><F><D><G><L><V><G><P><T><H><N><Y><A><G><L><S><F><G><N><V><A><S><L><N><N><E><K><S><A><A><N><P><K><A><A><A><K><Q><G><L><R><K><M><K><Q><L><A><D><L><G><F><A><Q><G><V><L><P><P><Q><E><R><P><S><L><R><L><L><R><E><L><G><F><S><G><K><D><A><D><V><I><A><K><A><A><K><Q><A><P><E><L><L><A><A><A><S><S><A><S><A><M><W... | Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).<BOP> | A4JCW1 |
Q0T6V4 | END8_SHIF8 | Endonuclease VIII | Shigella | <M><P><E><G><P><E><I><R><R><A><A><D><N><L><E><A><A><I><K><G><K><P><L><T><D><V><W><F><A><F><P><Q><L><K><T><Y><Q><S><Q><L><I><G><Q><H><V><T><H><V><E><T><R><G><K><A><L><L><T><H><F><P><N><G><L><T><L><Y><S><H><N><Q><L><Y><G><V><W><R><V><V><D><T><G><E><E><P><Q><T><T><R><V><L><R><V><K><L><Q><T><A><D><K><T><I><L><L><Y><S><A><S... | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduce... | Q0T6V4 |
P65259 | LDH_STRP1 | L-lactate dehydrogenase | Streptococcus | <M><T><A><T><K><Q><H><K><K><V><I><L><V><G><D><G><A><V><G><S><S><Y><A><F><A><L><V><T><Q><N><I><A><Q><E><L><G><I><I><D><I><F><K><E><K><T><Q><G><D><A><E><D><L><S><H><A><L><A><F><T><S><P><K><K><I><Y><A><A><D><Y><S><D><C><H><D><A><D><L><V><V><L><T><A><G><A><P><Q><K><P><G><E><T><R><L><D><L><V><E><K><N><L><R><I><N><K><E><V><V... | Catalyzes the conversion of lactate to pyruvate.<BOP> | P65259 |
Q8ZAP9 | THIG_YERPE | Thiazole synthase | Yersinia | <M><L><K><I><A><D><T><T><F><T><S><R><L><F><T><G><T><G><K><F><S><S><P><E><L><M><L><E><A><L><R><A><S><G><S><Q><L><I><T><M><A><M><K><R><V><D><L><Q><S><G><N><D><A><I><L><A><P><L><R><Q><L><G><V><R><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><R><L><A><R><E><A><L><N><T><H><W><V><K><L><E><V><H><P><D><V><R><Y><L><L><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | Q8ZAP9 |
Q741V3 | GLMU_MYCPA | Glucosamine-1-phosphate N-acetyltransferase | Mycobacterium avium complex (MAC) | <M><S><S><P><G><D><T><A><V><L><V><L><A><A><G><P><G><T><R><M><R><S><D><T><P><K><V><L><H><P><L><G><G><R><S><M><L><S><H><L><L><H><A><I><A><K><V><A><P><Q><H><L><A><V><V><L><G><H><D><H><E><R><I><A><P><L><I><A><D><W><A><D><D><L><G><R><P><I><D><V><A><L><Q><E><R><P><R><G><T><G><D><A><V><R><C><G><L><S><A><L><P><D><D><Y><A><G><V... | Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ... | Q741V3 |
Q92445 | DCOR_PARBR | Ornithine decarboxylase | Paracoccidioides | <G><V><S><F><H><V><G><S><G><A><E><D><P><K><S><F><V><K><A><V><E><D><S><R><F><V><F><D><Q><A><A><E><V><G><F><D><L><K><V><L><D><V><G><G><G><F><S><E><D><T><F><E><R><F><A><A><T><L><S><D><A><L><D><E><Y><F><P><P><H><I><R><I><I><A><E><P><G><R><I> | Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.<BOP> | Q92445 |
A6GXP5 | AROC_FLAPJ | 5-enolpyruvylshikimate-3-phosphate phospholyase | Flavobacterium | <M><S><G><N><S><Y><G><K><I><F><K><I><T><T><F><G><E><S><H><G><E><A><L><G><G><I><I><D><G><C><P><P><N><I><I><L><D><L><D><A><I><Q><I><E><M><Q><R><R><K><P><G><Q><S><S><I><V><T><Q><R><K><E><A><D><E><V><Q><F><L><S><G><I><F><E><G><K><T><T><G><T><P><I><G><F><I><I><K><N><T><N><Q><K><S><D><D><Y><S><H><I><K><D><S><Y><R><P><S><H><A... | Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s... | A6GXP5 |
Q9SR62 | RLPH2_ARATH | Protein RHIZOBIALE-LIKE PHOSPHATASE 2 | Arabidopsis | <M><A><Q><K><P><R><T><V><I><C><V><G><D><I><H><G><Y><I><S><K><L><N><N><L><W><L><N><L><Q><S><A><I><D><P><S><D><F><S><S><A><L><V><I><F><L><G><D><Y><C><D><R><G><P><E><T><R><K><V><I><D><F><L><I><S><L><P><E><K><H><P><D><Q><T><H><V><F><L><A><G><N><H><D><F><A><F><S><G><F><L><G><L><L><P><R><P><S><D><G><S><D><L><K><D><T><W><K><E... | Protein phosphatase that dephosphorylates specifically tyrosine-phosphorylated peptides; especially active on dual-phosphorylated substrates containing a phosphothreonine-X-phosphotyrosine motif.<BOP> | Q9SR62 |
B1LWT3 | RL16_METRJ | 50S ribosomal protein L16 | Methylobacterium | <M><L><Q><P><K><K><T><R><F><R><K><Q><F><K><G><R><I><H><G><A><A><K><G><G><F><E><L><N><F><G><Q><F><G><L><K><A><V><E><P><E><R><V><T><A><R><Q><I><E><A><A><R><R><A><I><T><R><E><M><K><R><Q><G><R><V><W><I><R><V><F><P><D><V><P><V><S><S><K><P><T><E><V><R><M><G><S><G><K><G><A><P><D><Y><W><A><A><R><V><H><P><G><R><I><M><F><E><V><D... | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP> | B1LWT3 |
A8DQI9 | NU4M_AVAUN | NADH dehydrogenase subunit 4 | Avahi | <M><L><K><I><I><I><P><T><I><M><L><F><P><V><T><W><Y><S><N><N><S><M><I><W><I><N><T><T><S><H><S><L><M><I><S><L><M><G><L><F><L><L><N><H><P><S><N><N><S><N><N><F><S><L><N><F><F><S><D><P><L><S><S><P><L><L><M><L><T><M><W><L><L><P><L><M><I><M><A><S><Q><Y><H><L><A><K><E><P><W><F><R><K><K><S><Y><L><S><M><L><I><T><L><Q><T><F><L><I... | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP> | A8DQI9 |
A7MK12 | MTND_CROS8 | Acireductone dioxygenase (Ni(2+)-requiring) | Cronobacter | <M><S><A><L><T><I><F><A><D><N><G><A><S><E><P><L><W><Q><S><T><D><A><D><A><I><R><E><Q><L><N><A><Q><G><V><R><F><E><R><W><Q><A><D><R><E><L><G><D><N><P><T><P><E><T><V><L><T><A><Y><Q><H><A><I><D><L><L><V><A><E><K><G><Y><Q><S><W><D><V><I><S><M><R><A><D><N><P><Q><K><E><A><L><R><D><K><F><L><N><E><H><T><H><G><E><D><E><V><R><F><F... | Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine... | A7MK12 |
Q9CGX1 | RF2_LACLA | Peptide chain release factor 2 | Lactococcus | <M><E><L><S><E><I><R><N><L><L><E><G><Y><A><E><K><I><N><G><F><R><E><S><L><D><L><E><R><L><E><E><E><I><A><L><L><E><N><D><M><A><Q><P><E><F><W><N><D><Q><A><A><A><Q><K><V><I><D><E><S><N><A><L><K><A><K><Y><D><N><Y><Q><A><M><N><N><M><L><E><E><A><Q><T><M><L><E><M><L><Q><E><E><A><D><E><E><M><Q><A><E><L><E><E><M><T><I><A><L><G><Q... | Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.<BOP> | Q9CGX1 |
Q8JFF3 | MKRN1_SERQU | RING-type E3 ubiquitin transferase makorin-1 | Seriola | <M><A><E><A><A><A><A><S><T><A><A><S><G><V><I><G><G><W><T><K><H><V><T><C><R><Y><F><M><H><G><L><C><K><E><G><D><N><C><R><Y><S><H><D><L><T><N><S><K><P><A><A><M><I><C><K><F><F><Q><K><G><N><C><V><F><G><D><R><C><R><F><E><H><C><K><P><A><K><N><E><E><L><P><A><P><Q><M><L><P><L><P><S><A><S><L><A><G><P><S><D><P><E><P><S><G><P><T><P... | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.<BOP> | Q8JFF3 |
Q5FS12 | MNMG_GLUOX | Glucose-inhibited division protein A | Gluconobacter | <M><S><D><F><D><V><I><V><I><G><G><G><H><A><G><C><E><A><A><A><A><S><A><R><F><G><A><R><T><L><L><L><T><H><R><L><E><T><I><G><A><M><S><C><N><P><A><I><G><G><I><G><K><G><H><L><V><R><E><I><D><A><L><D><G><L><M><G><K><A><A><D><R><A><G><I><H><F><K><L><L><N><R><S><K><G><P><A><V><H><G><P><R><A><Q><A><D><R><S><L><Y><R><A><A><I><Q><D... | NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP> | Q5FS12 |
Q3MB44 | RBSA_TRIV2 | Ribose import ATP-binding protein RbsA | Trichormus | <M><T><T><N><I><K><T><D><F><S><P><P><A><T><A><T><P><V><L><E><M><Q><G><I><A><K><R><F><H><G><V><P><A><L><Q><G><V><N><L><T><I><Y><P><G><E><V><H><A><L><M><G><E><N><G><A><G><K><S><T><L><M><K><I><L><A><G><A><Y><I><A><D><E><G><E><I><R><I><N><G><K><G><V><K><I><T><D><P><G><T><A><R><Q><A><G><I><N><L><I><Y><Q><E><L><N><V><A><P><N... | Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.<BOP> | Q3MB44 |
P02454 | CO1A1_RAT | Alpha-1 type I collagen | Rattus | <M><F><S><F><V><D><L><R><L><L><L><L><L><G><A><T><A><L><L><T><H><G><Q><E><D><I><P><E><V><S><C><I><H><N><G><L><R><V><P><N><G><E><T><W><K><P><D><V><C><L><I><C><I><C><H><N><G><T><A><V><C><D><G><V><L><C><K><E><D><L><D><C><P><N><P><Q><K><R><E><G><E><C><C><P><F><C><P><E><E><Y><V><S><P><D><A><E><V><I><G><V><E><G><P><K><G><D><P... | Type I collagen is a member of group I collagen (fibrillar forming collagen).<BOP> | P02454 |
C5DDM1 | RSSA_LACTC | 40S ribosomal protein S0 | Lachancea | <M><S><L><P><A><T><F><D><L><T><P><E><D><A><Q><L><L><L><A><A><N><V><H><L><G><S><K><N><V><Q><V><H><Q><E><P><Y><V><F><K><T><R><P><D><G><V><N><V><V><N><V><G><K><T><W><E><K><I><V><L><A><A><R><I><I><A><A><I><P><N><P><E><D><V><V><A><I><S><S><R><T><Y><G><Q><R><A><V><L><K><F><S><A><H><T><G><A><T><A><I><A><G><R><F><T><P><G><S><F... | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.<BOP> | C5DDM1 |
Q8WYL5 | SSH1_HUMAN | SSH-like protein 1 | Homo | <M><A><L><V><T><L><Q><R><S><P><T><P><S><A><A><S><S><S><A><S><N><S><E><L><E><A><G><S><E><E><D><R><K><L><N><L><S><L><S><E><S><F><F><M><V><K><G><A><A><L><F><L><Q><Q><G><S><S><P><Q><G><Q><R><S><L><Q><H><P><H><K><H><A><G><D><L><P><Q><H><L><Q><V><M><I><N><L><L><R><C><E><D><R><I><K><L><A><V><R><L><E><S><A><W><A><D><R><V><R><Y... | Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and in... | Q8WYL5 |
A6S043 | EIF3C_BOTFB | Translation initiation factor eIF3, p93 subunit homolog | Botrytis | <M><S><R><F><F><R><G><D><S><S><S><D><S><S><S><D><E><E><E><D><L><Y><S><D><D><E><E><V><Q><E><Q><P><E><E><E><S><S><E><D><D><S><E><E><D><D><D><D><D><D><D><S><D><S><S><S><D><D><G><A><G><K><K><T><G><A><N><A><F><L><K><D><D><S><D><S><D><S><E><S><S><G><D><E><G><V><K><V><V><K><S><A><K><N><K><R><F><E><E><L><E><A><T><A><K><A><I><E... | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates t... | A6S043 |
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