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[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.683.None
2.78
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.327.Neoplasms benign, malignant and unspecified (incl cysts and polyps)
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.8.Cardiac disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.652.Psychiatric disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.1013.Neoplasms benign, malignant and unspecified (incl cysts and polyps)
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.696.Metabolism and nutrition disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.199.Musculoskeletal and connective tissue disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound serve as an inhibitor of HIV replication.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemic...
property_prediction-hiv
property_prediction-hiv.train.17648.None
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.757.Congenital, familial and genetic disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.253.Cardiac disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.1738.None
3.21
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.238.Psychiatric disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.112.None
2.37
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound serve as an inhibitor of HIV replication.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemic...
property_prediction-hiv
property_prediction-hiv.train.31728.None
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.26.Pregnancy, puerperium and perinatal conditions
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.778.Neoplasms benign, malignant and unspecified (incl cysts and polyps)
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.865.Blood and lymphatic system disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.488.Renal and urinary disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.74.Ear and labyrinth disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.1605.None
2.82
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound serve as an inhibitor of HIV replication.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemic...
property_prediction-hiv
property_prediction-hiv.train.18507.None
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.897.Hepatobiliary disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.607.Psychiatric disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.102.Immune system disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.49.Vascular disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.232.Eye disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.259.Eye disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.847.None
3.4
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.516.Vascular disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.21.Gastrointestinal disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.680.Vascular disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.690.Vascular disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.500.Pregnancy, puerperium and perinatal conditions
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.984.Reproductive system and breast disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.658.Respiratory, thoracic and mediastinal disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether blood-brain barrier permeability (BBBP) is a property of the compound.\n The input contains the compound. Your reply should only contain Yes or No. Your reply must be ...
property_prediction-bbbp
property_prediction-bbbp.train.798.None
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether blood-brain barrier permeability (BBBP) is a property of the compound.\n The input contains the compound. Your reply should only contain Yes or No. Your reply must be ...
property_prediction-bbbp
property_prediction-bbbp.train.522.None
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.536.Gastrointestinal disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether blood-brain barrier permeability (BBBP) is a property of the compound.\n The input contains the compound. Your reply should only contain Yes or No. Your reply must be ...
property_prediction-bbbp
property_prediction-bbbp.train.970.None
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.592.Gastrointestinal disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.261.Psychiatric disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of reactants and reagents, your task is to predict the potential product using your chemical reaction knowledge.\n The input contains both reactants and reagents, and different reactants and reagents are separated by...
forward_synthesis
forward_synthesis.train.936570.None
CCOC(=O)C1=CC(Br)=CC=C1N
<SMILES>
</SMILES>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.726.None
3.12
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the octanol/water partition coefficient of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain the octanol/water partition coe...
property_prediction-lipo
property_prediction-lipo.train.794.None
3.2
<NUMBER>
</NUMBER>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound is toxic.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQuestion: <SMI...
property_prediction-clintox
property_prediction-clintox.train.277.None
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound serve as an inhibitor of HIV replication.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemic...
property_prediction-hiv
property_prediction-hiv.train.27668.None
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.346.Gastrointestinal disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.1107.Ear and labyrinth disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the SMILES representation of compounds, your task is to predict the molecular formula of the compound.\n The input contains the SMILES representation of the compound. Your reply should contain only the molecular formula of the compound wrappe...
name_conversion-s2f
name_conversion-s2f.train.182451.None
C17H29N3O3
<MOLFORMULA>
</MOLFORMULA>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.867.Nervous system disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.1096.Metabolism and nutrition disorders
Yes
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound has any side effects.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemically reasonable.\nQu...
property_prediction-sider
property_prediction-sider.train.471.Cardiac disorders
No
<BOOLEAN>
</BOOLEAN>
[ { "role": "user", "content": "You are an expert chemist. Given the smiles representation of the compound, your task is to predict whether the compound serve as an inhibitor of HIV replication.\n The input contains the compound. Your reply should contain only Yes or No. Your reply must be valid and chemic...
property_prediction-hiv
property_prediction-hiv.train.21712.None
No
<BOOLEAN>
</BOOLEAN>
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