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Discover the cosmos! Each day a different image or photograph of our fascinating universe is featured, along with a brief explanation written by a professional astronomer. |
2010 August 12 |
Explanation: Each August, as planet Earth swings through dust trailing along the orbit of periodic comet Swift-Tuttle, skygazers can enjoy the Perseid Meteor Shower. The shower should build to its peak now, best seen from later tonight after moonset, until dawn tomorrow morning when Earth moves through the denser part ... |
Authors & editors: |
Jerry Bonnell (UMCP) |
NASA Official: Phillip Newman Specific rights apply. |
A service of: ASD at NASA / GSFC |
& Michigan Tech. U. |
1. Why is extremism an issue in prisons? |
Extremist groups often pose special security risks in prisons. They may encourage the overthrow of the government, and prison officials can be targeted as agents of "illegal" government authority. Further, their literature often encourages ethnic hatred, promoting a violent and racially charged prison atmosphere. |
Since the 1980s, white supremacist organizations have spread throughout the American prison system, beginning with the growth of Aryan Brotherhood.1 Aryan Nations, although not permitting inmates to become members, has engaged in "prison outreach" since 1979. In 1987, it began publishing a "prison outreach newsletter" ... |
Imprisoned extremists also pose a security threat by continuing their activities while incarcerated. They recruit inmates, and teach other inmates extremist tactics. Some imprisoned extremists also have attempted to continue to influence adherents outside of prison by, for instance, publishing newsletters from the pris... |
Prison officials have responded in various ways, reflecting the fact that each state has its own prison system (as do cities, counties and the federal government), and that prisons have varying populations. At times, prison officials have tried to limit access to extremist literature, and these responses have occasiona... |
1 Aryan Brotherhood, at one time associated with Aryan Nations, began as a virulent racist and anti-Semitic prison gang, and has since developed into a crime gang associated with extortion, drug operations and prison violence. |
2. Do inmates have the same First Amendment rights as everybody else? |
The United States Supreme Court has said that "prison walls do not form a barrier separating prison inmates from the protections of the Constitution." Nevertheless, inmates' First Amendment rights are less extensive than other citizens' and their rights can be limited due to security or other penological concerns. Beca... |
A prison regulation that impinges on an inmate's constitutional rights will be upheld in court if that regulation is reasonably related to legitimate penological objectives. This means that, generally, prison officials can ban extremist materials from prisons because of concerns that the distribution of such material w... |
However, prisons have less discretion to limit inmates' religious practices than other First Amendment rights due to a new federal law. Because of the Religious Land Use and Institutionalized Persons Act (RLUIPA), prison officials' discretion in limiting access to extremist material may depend in part on whether such m... |
3. What legal standard is used to determine the constitutionality of prison regulations? |
The Supreme Court announced the standard under which it would review the constitutionality of prison regulations in Turner v. Safley, a case involving a challenge to a complete prohibition on inmate marriage. As noted earlier, a prison regulation is constitutional if it is reasonably related to legitimate penological o... |
- Is there a valid, rational connection between the prison regulation and the legitimate governmental |
interest put forward to justify it? |
- Are there alternative means of exercising the assert- ed right that remain open to inmates? |
- How great a negative impact will accommodating the inmates' rights have on guards, other inmates,a |
nd on the allocation of prison resources? |
Courts will consider the existence of obvious and easy alternatives to a challenged regulation as evidence of a regulation's arbitrariness. |
4. Is the same legal standard used to determine the constitutionality of prison regulations that implicate an inmate's right to free exercise of religion? |
No, the same standard is not applicable to determining the constitutionality of prison regulations alleged to violate inmates' free exercise rights. The constitutionality of such regulations is determined under the more stringent standard set forth in RLUIPA. RLUIPA says that the government cannot impose a substantial ... |
Since RLUIPA was enacted in September 2000, it has not yet been interpreted by the courts. Therefore, how this statute will impact prison regulations that affect inmates' religious exercise remains unclear. |
5. How should prison officials evaluate whether particular material can be withheld from inmates? |
Generally, the First Amendment does not allow speech to be censored by the government because of the content of that speech. The government can only limit the time, place, and manner of speech. However, because inmates have more limited First Amendment rights than other citizens, some content-based discrimination is al... |
Regulations that exclude publications from a prison because of security concerns have been found constitutional when the regulations have required individualized review of any material before it is banned, notification to inmates that the material has been denied, and the possibility of review of such decisions. Courts... |
6. Can prison officials apply the same restrictions to outgoing prison material? |
The Supreme Court does not allow content regulation with respect to outgoing mail from inmates. While outgoing mail can be searched for contraband,2 content regulation of outgoing mail is also more restricted because it implicates the First Amendment rights of non-prisoner addressees.3 In addition, outgoing material do... |
2 Special rules exist with respect to attorney-client correspondence or mail that implicates an inmate's right to access the courts that are beyond the scope of this discussion. |
3 However, prison officials can forbid all correspondence between incarcerated individuals. |
7. Can extremist "missionaries" be prevented from visiting prisons? |
Prison officials can ban categories of prison visitors, such as former inmates or visitors who have previously broken visiting rules. An extremist "missionary" can be barred from a prison because of generally applicable rules. In addition, prisons can create procedures for requesting visiting ministers, and impose cond... |
Prison officials do not have a responsibility to hire a minister for each religious denomination represented in the prison population. However, if visiting ministers of one denomination are compensated, visiting ministers of other denominations must be equally compensated. Security limitations can be placed on inmate-l... |
8. Under what circumstances must prisons accommodate prisoners' religious dietary requirements? |
Accommodating religiously based dietary rules has become an issue when dealing with extremists because incidents have raised concern that extremists "adopt" religious practices that are not based on sincere beliefs in order to obtain special privileges, such as specialized diets. Generally, if an inmate's request for a... |
Wikipedia sobre física de partículas |
Rapidinho. Me falaram que a definição de física de partículas da Wikipedia era muito ruim. E de fato, era assim: |
Particle physics is a branch of physics that studies the elementary particle|elementary subatomic constituents of matter and radiation, and their interactions. The field is also called high energy physics, because many elementary particles do not occur under ambient conditions on Earth. They can only be created artific... |
Particle physics has evolved out of its parent field of nuclear physics and is typically still taught in close association with it. Scientific research in this area has produced a long list of particles. |
Mas hein? Partículas que só podem ser criadas em aceleradores? Física de partículas é ensinada junto com física nuclear? A pesquisa produz partículas (essa é ótima!)? |
Em que mundo essa pessoa vive? Reescrevi: |
Particle Physics is a branch of physics that studies the existence and interactions of particles, which are the constituents of what is usually referred as matter or radiation. In our current understanding, particles are excitations of quantum fields and interact following their dynamics. Most of the interest in this a... |
Eu acho que ficou bem melhor. Vamos ver em quanto tempo algum editor esquentado da Wikipedia vai demorar para reverter. Atualmente está um saco participar da Wikipedia por causa dessas pessoas. |
- published: 19 Mar 2013 |
- views: 42 |
- author: T.A. B |
possibly testing on weans, that worries me http://www.bbc.co.uk/news/world-us-canada-21849808. |
A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune sy... |
Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by any natural or "wild" pathogen), or therapeutic (e.g. vaccines against cancer are also being investigated; see cancer vaccine). |
The term vaccine derives from Edward Jenner's 1796 use of cow pox (Latin variola vaccinia, adapted from the Latin vaccīn-us, from vacca, cow), to inoculate humans, providing them protection against smallpox. |
Vaccines do not guarantee complete protection from a disease. Sometimes, this is because the host's immune system simply does not respond adequately or at all. This may be due to a lowered immunity in general (diabetes, steroid use, HIV infection, age) or because the host's immune system does not have a B cell capable ... |
Even if the host develops antibodies, the human immune system is not perfect and in any case the immune system might still not be able to defeat the infection immediately. In this case, the infection will be less severe and heal faster. |
Adjuvants are typically used to boost immune response. Most often aluminium adjuvants are used, but adjuvants like squalene are also used in some vaccines and more vaccines with squalene and phosphate adjuvants are being tested. Larger doses are used in some cases for older people (50–75 years and up), whose immune res... |
The efficacy or performance of the vaccine is dependent on a number of factors: |
When a vaccinated individual does develop the disease vaccinated against, the disease is likely to be milder than without vaccination. |
The following are important considerations in the effectiveness of a vaccination program: |
In 1958 there were 763,094 cases of measles and 552 deaths in the United States. With the help of new vaccines, the number of cases dropped to fewer than 150 per year (median of 56). In early 2008, there were 64 suspected cases of measles. 54 out of 64 infections were associated with importation from another country, a... |
Vaccines are dead or inactivated organisms or purified products derived from them. |
There are several types of vaccines in use. These represent different strategies used to try to reduce risk of illness, while retaining the ability to induce a beneficial immune response. |
Some vaccines contain killed, but previously virulent, micro-organisms that have been destroyed with chemicals, heat, radioactivity or antibiotics. Examples are the influenza vaccine, cholera vaccine, bubonic plague vaccine, polio vaccine, hepatitis A vaccine, and rabies vaccine. |
Some vaccines contain live, attenuated microorganisms. Many of these are live viruses that have been cultivated under conditions that disable their virulent properties, or which use closely related but less dangerous organisms to produce a broad immune response. Although most attenuated vaccines are viral, some are bac... |
Toxoid vaccines are made from inactivated toxic compounds that cause illness rather than the micro-organism. Examples of toxoid-based vaccines include tetanus and diphtheria. Toxoid vaccines are known for their efficacy. Not all toxoids are for micro-organisms; for example, Crotalus atrox toxoid is used to vaccinate do... |
Protein subunit – rather than introducing an inactivated or attenuated micro-organism to an immune system (which would constitute a "whole-agent" vaccine), a fragment of it can create an immune response. Examples include the subunit vaccine against Hepatitis B virus that is composed of only the surface proteins of the ... |
Conjugate – certain bacteria have polysaccharide outer coats that are poorly immunogenic. By linking these outer coats to proteins (e.g. toxins), the immune system can be led to recognize the polysaccharide as if it were a protein antigen. This approach is used in the Haemophilus influenzae type B vaccine. |
A number of innovative vaccines are also in development and in use: |
While most vaccines are created using inactivated or attenuated compounds from micro-organisms, synthetic vaccines are composed mainly or wholly of synthetic peptides, carbohydrates or antigens. |
Vaccines may be monovalent (also called univalent) or multivalent (also called polyvalent). A monovalent vaccine is designed to immunize against a single antigen or single microorganism. A multivalent or polyvalent vaccine is designed to immunize against two or more strains of the same microorganism, or against two or ... |
The immune system recognizes vaccine agents as foreign, destroys them, and "remembers" them. When the virulent version of an agent comes along the body recognizes the protein coat on the virus, and thus is prepared to respond, by (1) neutralizing the target agent before it can enter cells, and (2) by recognizing and de... |
When two or more vaccines are mixed together in the same formulation, the two vaccines can interfere. This most frequently occurs with live attenuated vaccines, where one of the vaccine components is more robust than the others and suppresses the growth and immune response to the other components. This phenomenon was f... |
Vaccines have contributed to the eradication of smallpox, one of the most contagious and deadly diseases known to man. Other diseases such as rubella, polio, measles, mumps, chickenpox, and typhoid are nowhere near as common as they were a hundred years ago. As long as the vast majority of people are vaccinated, it is ... |
In order to provide best protection, children are recommended to receive vaccinations as soon as their immune systems are sufficiently developed to respond to particular vaccines, with additional "booster" shots often required to achieve "full immunity". This has led to the development of complex vaccination schedules.... |
Besides recommendations for infant vaccinations and boosters, many specific vaccines are recommended at other ages or for repeated injections throughout life—most commonly for measles, tetanus, influenza, and pneumonia. Pregnant women are often screened for continued resistance to rubella. The human papillomavirus vacc... |
Sometime during the 1770s Edward Jenner heard a milkmaid boast that she would never have the often-fatal or disfiguring disease smallpox, because she had already had cowpox, which has a very mild effect in humans. In 1796, Jenner took pus from the hand of a milkmaid with cowpox, inoculated an 8-year-old boy with it, an... |
The twentieth century saw the introduction of several successful vaccines, including those against diphtheria, measles, mumps, and rubella. Major achievements included the development of the polio vaccine in the 1950s and the eradication of smallpox during the 1960s and 1970s. Maurice Hilleman was the most prolific of ... |
||The neutrality of this section is disputed. Please see the discussion on the talk page. Please do not remove this message until the dispute is resolved. (October 2011)| |
||This article is missing information about Scientific rebuttal to the attacks. This concern has been noted on the talk page where whether or not to include such information may be discussed. (October 2011)| |
Opposition to vaccination, from a wide array of vaccine critics, has existed since the earliest vaccination campaigns. Although the benefits of preventing suffering and death from serious infectious diseases greatly outweigh the risks of rare adverse effects following immunization, disputes have arisen over the moralit... |
One challenge in vaccine development is economic: many of the diseases most demanding a vaccine, including HIV, malaria and tuberculosis, exist principally in poor countries. Pharmaceutical firms and biotechnology companies have little incentive to develop vaccines for these diseases, because there is little revenue po... |
Most vaccine development to date has relied on "push" funding by government, universities and non-profit organizations. Many vaccines have been highly cost effective and beneficial for public health. The number of vaccines actually administered has risen dramatically in recent decades.[when?] This increase, particularl... |
The filing of patents on vaccine development processes can also be viewed as an obstacle to the development of new vaccines. Because of the weak protection offered through a patent on the final product, the protection of the innovation regarding vaccines is often made through the patent of processes used on the develop... |
Vaccine production has several stages. First, the antigen itself is generated. Viruses are grown either on primary cells such as chicken eggs (e.g., for influenza), or on continuous cell lines such as cultured human cells (e.g., for hepatitis A). Bacteria are grown in bioreactors (e.g., Haemophilus influenzae type b). ... |
Vaccine production techniques are evolving. Cultured mammalian cells are expected to become increasingly important, compared to conventional options such as chicken eggs, due to greater productivity and low incidence of problems with contamination. Recombination technology that produces genetically detoxified vaccine i... |
In 2010, India produced 60 percent of world's vaccine worth about $900 million. |
Many vaccines need preservatives to prevent serious adverse effects such as Staphylococcus infection that, in one 1928 incident, killed 12 of 21 children inoculated with a diphtheria vaccine that lacked a preservative. Several preservatives are available, including thiomersal, phenoxyethanol, and formaldehyde. Thiomers... |
There are several new delivery systems in development[when?] that will hopefully make vaccines more efficient to deliver. Possible methods include liposomes and ISCOM (immune stimulating complex). |
The latest developments[when?] in vaccine delivery technologies have resulted in oral vaccines. A polio vaccine was developed and tested by volunteer vaccinations with no formal training; the results were positive in that the ease of the vaccines increased. With an oral vaccine, there is no risk of blood contamination.... |
A nanopatch is a needle free vaccine delivery system which is under development. A stamp-sized patch similar to an adhesive bandage contains about 20,000 microscopic projections per square inch. When worn on the skin, it will deliver vaccine directly to the skin, which has a higher concentration of immune cells than th... |
The use of plasmids has been validated in preclinical studies as a protective vaccine strategy for cancer and infectious diseases. However, in human studies this approach has failed to provide clinically relevant benefit. The overall efficacy of plasmid DNA immunization depends on increasing the plasmid's immunogenicit... |
Vaccinations of animals are used both to prevent their contracting diseases and to prevent transmission of disease to humans. Both animals kept as pets and animals raised as livestock are routinely vaccinated. In some instances, wild populations may be vaccinated. This is sometimes accomplished with vaccine-laced food ... |
Where rabies occurs, rabies vaccination of dogs may be required by law. Other canine vaccines include canine distemper, canine parvovirus, infectious canine hepatitis, adenovirus-2, leptospirosis, bordatella, canine parainfluenza virus, and Lyme disease among others. |
Vaccine development has several trends: |
Principles that govern the immune response can now be used in tailor-made vaccines against many noninfectious human diseases, such as cancers and autoimmune disorders. For example, the experimental vaccine CYT006-AngQb has been investigated as a possible treatment for high blood pressure. Factors that have impact on th... |
|Modern Vaccine and Adjuvant Production and Characterization, Genetic Engineering & Biotechnology News| |
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