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{'text': "###Human:\nAre granisetron and palonosetron used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['granisetron', 'palonosetron'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong naproxen, celecoxib, and rofecoxib, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['naproxen', 'celecoxib', 'rofecoxib'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre vincristine and methotrexate used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['vincristine', 'methotrexate'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre omeprazole and clopidogrel used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['omeprazole', 'clopidogrel'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAmong cyclophosphamide, rituximab, and pentostatin, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['cyclophosphamide', 'rituximab', 'pentostatin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre isoniazid and rifapentine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['isoniazid', 'rifapentine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong docetaxel, vinblastine, doxorubicin, cisplatin, paclitaxel, docetaxel, and vinblastine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['docetaxel', 'vinblastine', 'paclitaxel', 'docetaxel', 'vinblastine'], 'comb_effect': 'positive'}, {'comb_drugs': ['doxorubicin', 'cisplatin'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre doxorubicin and cyclophosphamide used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['doxorubicin', 'cyclophosphamide'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre amitriptyline and nortriptyline used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['amitriptyline', 'nortriptyline'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre docetaxel and paclitaxel used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['docetaxel', 'paclitaxel'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre alisertib and abiraterone used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['alisertib', 'abiraterone'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAmong Tanespimycin, trastuzumab, and trastuzumab, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Tanespimycin', 'trastuzumab'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong mefloquine, chloroquine, chloroquine, and proguanil, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['mefloquine', 'chloroquine', 'chloroquine', 'proguanil'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre phenytoin and methylprednisolone used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['phenytoin', 'methylprednisolone'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre Artesunate and Dihydroartemisinin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['Artesunate', 'Dihydroartemisinin'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong bortezomib, gemcitabine, and gemcitabine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['bortezomib', 'gemcitabine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre afatinib and bevacizumab used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['afatinib', 'bevacizumab'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong enzalutamide, docetaxel, and abiraterone, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['enzalutamide', 'docetaxel', 'abiraterone'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong cyclophosphamide, prednisone, cyclophosphamide, and prednisone, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['cyclophosphamide', 'prednisone', 'cyclophosphamide', 'prednisone'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong cediranib, gefitinib, and cediranib, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['cediranib', 'gefitinib'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAmong Chloroquine, Hydroxychloroquine, and Remdesivir, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['Chloroquine', 'Hydroxychloroquine', 'Remdesivir'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre bevacizumab and ranibizumab used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['bevacizumab', 'ranibizumab'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong streptomycin, amikacin, streptomycin, kanamycin, penicillin, and penicillin, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['streptomycin', 'penicillin'], 'comb_effect': 'positive'}, {'comb_drugs': ['amikacin', 'penicillin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong cyclophosphamide, vincristine, and dacarbazine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['cyclophosphamide', 'vincristine', 'dacarbazine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong ciprofloxacin, ceftazidime, and ampicillin, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['ciprofloxacin', 'ceftazidime', 'ampicillin'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre Paclitaxel and docetaxel used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['Paclitaxel', 'docetaxel'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre vinblastine and bleomycin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['vinblastine', 'bleomycin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong vincristine, cyclophosphamide, and 5-fluoro-uracil, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['vincristine', 'cyclophosphamide', '5-fluoro-uracil'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre estramustine and etoposide used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['estramustine', 'etoposide'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre bendamustine and ofatumumab used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['bendamustine', 'ofatumumab'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre gemcitabine and oxaliplatin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['gemcitabine', 'oxaliplatin'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAmong rituximab, intravenous immunoglobulin, and bortezomib, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['rituximab', 'intravenous immunoglobulin'], 'comb_effect': 'negative'}, {'comb_drugs': ['rituximab', 'bortezomib'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAmong methylprednisolone, cyclosporine, and azathioprine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['methylprednisolone', 'cyclosporine', 'azathioprine'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAmong R-CHOP, cyclophosphamide, vincristine, prednisone, fludarabine, and mitoxantrone, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['methylprednisolone', 'cyclosporine', 'azathioprine'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong gemcitabine, paclitaxel, and capecitabine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['gemcitabine', 'paclitaxel', 'capecitabine'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong voriconazole, amphotericin, and B., is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['voriconazole', 'amphotericin', 'B.'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAre Aspirin and Cilostazol used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Aspirin', 'Cilostazol'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre Gemcitabine and vinorelbine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Gemcitabine', 'vinorelbine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre tenofovir disoproxil fumarate and emtricitabine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['tenofovir disoproxil fumarate', 'emtricitabine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong tamoxifen, exemestane, and anastrozole, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['tamoxifen', 'exemestane', 'anastrozole'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre rosiglitazone and glimepiride used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['rosiglitazone', 'glimepiride'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong doxorubicin, cyclophosphamide, and paclitaxel, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['doxorubicin', 'cyclophosphamide', 'paclitaxel'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAmong cisplatin, cyclophosphamide, and paclitaxel, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['cisplatin', 'cyclophosphamide'], 'comb_effect': 'negative'}, {'comb_drugs': ['cisplatin', 'paclitaxel'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre ezetimibe and simvastatin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['ezetimibe', 'simvastatin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong pseudoephedrine, methamphetamine, and methamphetamine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['pseudoephedrine', 'methamphetamine', 'methamphetamine'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong procarbazine, lomustine, vincristine, and radiotherapy, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['procarbazine', 'lomustine', 'vincristine', 'radiotherapy'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre vinorelbine and gemcitabine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['vinorelbine', 'gemcitabine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong Tobramycin, gentamicin, and penicillins, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Tobramycin', 'penicillins'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre entecavir and telbivudine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['entecavir', 'telbivudine'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong ixabepilone, paclitaxel, capecitabine, vinorelbine, pemetrexed, and irinotecan, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['ixabepilone', 'paclitaxel', 'capecitabine', 'vinorelbine', 'pemetrexed', 'irinotecan'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong fluticasone, formoterol, fluticasone, and formoterol, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['fluticasone', 'formoterol'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre anastrozole and tamoxifen used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['anastrozole', 'tamoxifen'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre tocilizumab and tofacitinib used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['tocilizumab', 'tofacitinib'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre Paclitaxel and fulvestrant used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Paclitaxel', 'fulvestrant'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong ritodrine, lidocaine, phenylephrine, and ephedrine, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['ritodrine', 'lidocaine', 'ephedrine'], 'comb_effect': 'positive'}, {'comb_drugs': ['ritodrine', 'lidocaine', 'phenylephrine'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre busulfan and cyclophosphamide used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['busulfan', 'cyclophosphamide'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre cyclosporine and prednisone used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['cyclosporine', 'prednisone'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAre Tadalafil and sildenafil used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['Tadalafil', 'sildenafil'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre heparin and enoxaparin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['heparin', 'enoxaparin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong leucovorin, levamisole, 5-FU, and 5-FU, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['5-FU', 'leucovorin'], 'comb_effect': 'positive'}, {'comb_drugs': ['5-FU', 'levamisole'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre tamoxifen and letrozole used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['tamoxifen', 'letrozole'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre sorafenib and flavopiridol used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['sorafenib', 'flavopiridol'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre sorafenib and curcumin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['sorafenib', 'curcumin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre closantel and albendazole used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['closantel', 'albendazole'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre lidocaine and tetracaine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['lidocaine', 'tetracaine'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre bevacizumab and irinotecan used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['bevacizumab', 'irinotecan'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre nivolumab and pembrolizumab used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['nivolumab', 'pembrolizumab'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre rapamycin and paclitaxel used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['rapamycin', 'paclitaxel'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong atezolizumab, bevacizumab, and sorafenib, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['atezolizumab', 'bevacizumab'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre tamoxifen and letrozole used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['tamoxifen', 'letrozole'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre nilotinib and ponatinib used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['nilotinib', 'ponatinib'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre somatostatin and everolimus used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['somatostatin', 'everolimus'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre trastuzumab and paclitaxel used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['trastuzumab', 'paclitaxel'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre basiliximab and cyclosporine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['basiliximab', 'cyclosporine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong posaconazole, posaconazole, and voriconazole, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['posaconazole', 'voriconazole'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre paclitaxel and capecitabine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['paclitaxel', 'capecitabine'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAre fluorouracil and leucovorin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['fluorouracil', 'leucovorin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre propranolol and phenylephrine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['propranolol', 'phenylephrine'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre paclitaxel and vinorelbine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['paclitaxel', 'vinorelbine'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre decitabine and valproic used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['decitabine', 'valproic'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAmong clopidogrel, aspirin, and clopidogrel, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['clopidogrel', 'aspirin', 'clopidogrel'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre docetaxel and irinotecan used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['docetaxel', 'irinotecan'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre paclitaxel and carboplatin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['paclitaxel', 'carboplatin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre oxaliplatin and docetaxel used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['oxaliplatin', 'docetaxel'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre luspatercept and venetoclax used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['luspatercept', 'venetoclax'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre enalapril and captopril used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['enalapril', 'captopril'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong imipenem, imipenem, and amphotericin, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['imipenem', 'amphotericin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['rituximab', 'cyclophosphamide', 'doxorubicin', 'vincristine', 'prednisolone'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAmong rituximab, vincristine, and cyclophosphamide, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['rituximab', 'vincristine', 'cyclophosphamide'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre lamotrigine and carbamazepine used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['carbamazepine'], 'comb_effect': 'negative'}, {'comb_drugs': ['lamotrigine'], 'comb_effect': 'neu'}]"},
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{'text': "###Human:\nAre decitabine and carboplatin used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['decitabine', 'carboplatin'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAmong vinblastine, bleomycin, and cis-platinum, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['vinblastine', 'bleomycin', 'cis-platinum'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong atenolol, metoprolol, acebutolol, oxprenolol, nadolol, timolol, and propranolol, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'drugs': ['atenolol', 'metoprolol', 'acebutolol', 'oxprenolol', 'nadolol', 'timolol', 'propranolol'], 'usage_status': 'not_combined'}]"},
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{'text': "###Human:\nAre raloxifene and nimesulide used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['raloxifene', 'nimesulide'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAre dolutegravir and tenofovir used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['dolutegravir', 'tenofovir'], 'comb_effect': 'negative'}]"},
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{'text': "###Human:\nAre Abiraterone and prednisone used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Abiraterone', 'prednisone'], 'comb_effect': 'undetermined'}]"},
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{'text': "###Human:\nAre Nivolumab and ipilimumab used in combination? If so, clearly state the effects of the combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['Nivolumab', 'ipilimumab'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong rapamycin, topotecan, and topotecan, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['rapamycin', 'topotecan'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong PNU-159548, doxorubicin, methotrexate, and cisplatin, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['PNU-159548', 'doxorubicin'], 'comb_effect': 'positive'}, {'comb_drugs': ['PNU-159548', 'methotrexate'], 'comb_effect': 'positive'}, {'comb_drugs': ['PNU-159548', 'cisplatin'], 'comb_effect': 'positive'}]"},
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{'text': "###Human:\nAmong human tumor necrosis factor, Etoposide, and Doxorubicin, is there any combination of these drugs used together? If so, please specify the exact combinations. Also, clearly state the effects of these combinations, choosing only from the following three options: positive effects, negative effects, or undetermined effects.\n\n###Assistant:\n[{'comb_drugs': ['human tumor necrosis factor', 'Etoposide'], 'comb_effect': 'positive'}, {'comb_drugs': ['human tumor necrosis factor', 'Doxorubicin'], 'comb_effect': 'positive'}]"},
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