| | --- |
| | license: other |
| | license_name: non-commercial-license-dyna1 |
| | license_link: https://github.com/WaymentSteeleLab/Dyna-1/blob/main/LICENSE.txt |
| | datasets: |
| | - gelnesr/RelaxDB |
| | base_model: |
| | - EvolutionaryScale/esm3-sm-open-v1 |
| | - facebook/esm2_t30_150M_UR50D |
| | tags: |
| | - proteins |
| | - nmr |
| | - dyna1 |
| | --- |
| | |
| | [](https://colab.research.google.com/github/WaymentSteeleLab/Dyna-1/blob/main/colab/Dyna_1.ipynb) |
| | [](https://github.com/WaymentSteeleLab/Dyna-1) |
| |
|
| | # Dyna-1 Model Card |
| |
|
| | Dyna-1 is a model introduced in our paper, ["Learning millisecond protein dynamics from what is missing in NMR spectra"](https://www.biorxiv.org/content/10.1101/2025.03.19.642801v1). |
| |
|
| | Given a sequence and/or structure, Dyna-1 will predict the probability that each residue experiences micro-millisecond motions. |
| |
|
| | Dyna-1 was achieved using the `esm3-sm-open-v1` weights from ESM-3. Inference with this model is subject to the EvolutionaryScale Cambrian Non-Commercial License Agreement of the ESM-3 Model and requires read permission of the weights found [here](https://huggingface.co/EvolutionaryScale/esm3-sm-open-v1). We also make available an alternate version of Dyna-1 that uses ESM-2 embeddings; use of this model is subject to a Non-Commercial License Agreement. |
| |
|
| | If you are using our code, datasets, or model, please use the following citation: |
| | ```bibtex |
| | @article {Dyna-1, |
| | author = {Wayment-Steele, Hannah K. and El Nesr, Gina and Hettiarachchi, Ramith and Kariyawasam, Hasindu and Ovchinnikov, Sergey and Kern, Dorothee}, |
| | title = {Learning millisecond protein dynamics from what is missing in NMR spectra}, |
| | year = {2025}, |
| | doi = {10.1101/2025.03.19.642801}, |
| | journal = {bioRxiv} |
| | } |
| | ``` |
| |  |
