irrrricardo/PODE_Weights

PODE Model Weights

Model-weight release for the submitted manuscript:

Decomposing retinal age-clock residuals reveals disease-associated systemic heterogeneity in human aging

Summary

PODE is a physiology-guided residual-decomposition framework for studying disease-associated heterogeneity around a healthy retinal aging trajectory. This repository hosts the public checkpoint packages for the fundus PODE implementation and the analogous BrainMRI implementation.

Code repository:

• https://github.com/irrrricardo/PODE

Packages

Directory	Checkpoint	Component
fundus_base/	pode_fundus_base.pth	Fundus PODE-Base
fundus_splitter/	pode_fundus_splitter.pth	Fundus PODE-Splitter
brain_mri_base/	pode_brain_mri_base.pth	BrainMRI PODE-Base
brain_mri_splitter/	pode_brain_mri_splitter.pth	BrainMRI PODE-Splitter

Public checkpoint filenames are version-free. Package provenance is tracked in metadata.json, manifest.json, and SHA256SUMS.

Notes

• No raw fundus images, MRI volumes, clinical tables, or subject-level manifests are included.
• Fundus PODE-Base uses the VisionFM backbone. If upstream VisionFM weights are required for a workflow, obtain them according to the upstream model's terms.
• BrainMRI workflows require authorized local data and consistent preprocessing.
• The checkpoints are research artifacts and are not intended for clinical decision-making.

Verification

Use manifest.json and each package-level metadata.json to verify file size and SHA256.

Contact

Ricardo Chu (GitHub/Hugging Face: irrrricardo)