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| license: mit |
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| # IgCraft: A generative model for paired human antibody sequence design |
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| This repository stores the model weights for IgCraft. You can read more about the model in our [paper](https://arxiv.org/abs/2503.19821), and use the model via our github [repo](https://github.com/mgreenig/IgCraft). |
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| IgCraft is a sequence generative model for that can sample full or partial paired human antibody sequences in a variety of design contexts. |
| The model has the ability to perform unconditional and conditional sampling and optionally condition on structural information when available. |
| In particular, the model performs de novo sequence generation, inpainting, inverse folding, and CDR motif scaffolding at levels competitive with |
| state-of-the-art task-specific models, while consistently producing antibody sequences with a better humanness profile than species-agnostic tools. |
