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MaziyarPanahi 
posted an update 8 days ago
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4137
DNA, mRNA, proteins, AI. I spent the last year going deep into computational biology as an ML engineer. This is Part I of what I found. 🧬

In 2024, AlphaFold won the Nobel Prize in Chemistry.

By 2026, the open-source community had built alternatives that outperform it.

That's the story I find most interesting about protein AI right now. Not just the science (which is incredible), but the speed at which open-source caught up. Multiple teams, independently, reproduced and then exceeded AlphaFold 3's accuracy with permissive licenses. The field went from prediction to generation: we're not just modeling known proteins anymore, we're designing new ones.

I spent months mapping this landscape for ML engineers. What the architectures actually are (spoiler: transformers and diffusion models), which tools to use for what, and which ones you can actually ship commercially.

New post on the Hugging Face blog: https://huggingface.co/blog/MaziyarPanahi/protein-ai-landscape

Hope you all enjoy! 🤗
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MaziyarPanahi 
posted an update 29 days ago
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2226
Announcing: OpenMed Multilingual PII Detection Models

Today I am releasing 105 open-source models for Personally Identifiable Information (PII) detection in French, German, and Italian.

All Apache 2.0 licensed. Free for commercial use. No restrictions.

Performance:

- French: 97.97% F1 (top model)
- German: 97.61% F1 (top model)
- Italian: 97.28% F1 (top model)

All top-10 models per language exceed 96% F1

Coverage:

55+ PII entity types per language
Native ID formats: NSS (French), Sozialversicherungsnummer (German), Codice Fiscale (Italian)
Language-specific address, phone, and name patterns

Training Data:

French: 49,580 samples
German: 42,250 samples
Italian: 40,944 samples

Why Multilingual?

European healthcare operates in European languages. Clinical notes, patient records, and medical documents are generated in French, German, Italian, and other languages.

Effective de-identification requires:

- Native language understanding — not translation
- Local ID format recognition — each country has unique patterns
- Cultural context awareness — names, addresses, and formats vary
- These models deliver production-ready accuracy without requiring data to leave your infrastructure or language.

HIPAA & GDPR Compliance
Built for US and European privacy regulations:

- On-premise deployment: Process data locally with zero external dependencies
- Data sovereignty: No API calls, no cloud services, no cross-border transfers
- Air-gapped capable: Deploy in fully isolated environments if required
- Regulatory-grade accuracy: Supporting Expert Determination standards
- HIPAA and GDPR compliance across languages, without compliance gaps.

Use Cases
- Hospital EHR systems: Automated patient record de-identification
- Clinical research: Multilingual dataset preparation for studies
- Insurance companies: Claims processing across

https://huggingface.co/collections/OpenMed/multilingual-pii-and-de-identification
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#1 opened about 1 month ago by
krustik
MaziyarPanahi 
posted an update about 1 month ago
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From Golden Gate Bridge to Broken JSON: Why Anthropic's SAE Steering Fails for Structured Output

I ran 6 experiments trying to use Anthropic's SAE steering for JSON generation.

- Base model: 86.8% valid JSON
- Steering only: 24.4%
- Fine-tuned: 96.6%
- FSM constrained: 100%

Steering is for semantics, not syntax.

https://huggingface.co/blog/MaziyarPanahi/sae-steering-json