Daily Papers

Purpose : To develop and evaluate CAPTOR, a deep-learning vision-language foundation model for oncologic chest-abdomen-pelvis (CAP) CT interpretation. Materials & Methods : CAPTOR (Chest-Abdomen-Pelvis foundaTion model for Oncologic Radiology) is a contrastive vision-language model, trained using a pretraining strategy for oncologic CAP CT (in single- or multiple-series acquisitions), on a multicenter retrospective dataset from North America, Europe and Asia, predominantly from tumor lesion examinations. CAPTOR was compared with state-of-the-art CT foundation models on three downstream tasks: disease detection, survival prediction using TumorImagingBench and image retrieval. Classification and retrieval were both evaluated on held-out internal and public test sets, stratified by anatomical coverage and indication. Bootstrap resampling was used to estimate confidence intervals, and pairwise comparisons were performed using permutation tests. Results : CAPTOR was trained and tested on 25,512 and 10,794 CT-report pairs respectively. TumorImagingBench datasets comprised between 134 and 421 studies each. CAPTOR outperformed all baseline models, on the classification task, on the CAP subset (AUC 0.767, 95%CI: 0.734-0.793, vs. 0.695, 95%CI: 0.645-0.736 for the next-best, p<0.001) and oncologic subset (AUC 0.784, 95%CI: 0.759-0.805, vs. 0.734, 95%CI: 0.703-0.767 p<0.001), ranked first on three of the four oncologic prognostic benchmarks, and achieved superior retrieval performance on CAP and oncologic subsets. Conclusion : A foundation model trained on oncology-enriched CAP CT data outperformed relevant state-of-the-art models in its target clinical context, underscoring the importance of clinically aligned pretraining. We release our preprocessing, training and inference code : https://github.com/Guerbet-AI/CAPTOR and model weights : https://huggingface.co/Guerbet-AI/CAPTOR

Grounding a text query in an image needs a matrix scoring every term against every patch. Vision-language models compute it with an aligned text encoder, which many image encoders, such as histopathology-related models trained on slides alone, lack. The Caption-Anchored Patch-Term Occurrence Representation (CAPTOR) estimates the matrix without a text encoder. It clusters a frozen image encoder's patch tokens into visual words and describes each captioned image by its share of patches in each word. A term signature is the standardized difference of those shares between images whose captions mention the term and the rest. The matrix factorizes into a term-by-word table and a query-independent image factor, so an image is encoded once and a new term adds one table row. Against every training-free baseline, CAPTOR leads on Common Objects in Context (COCO), Pascal Visual Object Classes (VOC) and Cityscapes. On COCO, scored on the cells one object owns, it reaches 0.565 mean intersection over union (mIoU) against 0.502. On all three, it is also level with a text alignment trained on the same backbone, which needs gradients, a text encoder and several times the captions. On held-out breast-cancer slides, it exceeds the strongest baseline scoring patches with a pathology text encoder by 0.160 mIoU. Read through CAPTOR, UNI, an encoder trained on slides alone, exceeds such baselines by 0.132 on a common grid. Counting can therefore give a text interface to any image encoder trained without language, wherever captioned images exist.

Books are typically segmented into chapters and sections, representing coherent subnarratives and topics. We investigate the task of predicting chapter boundaries, as a proxy for the general task of segmenting long texts. We build a Project Gutenberg chapter segmentation data set of 9,126 English novels, using a hybrid approach combining neural inference and rule matching to recognize chapter title headers in books, achieving an F1-score of 0.77 on this task. Using this annotated data as ground truth after removing structural cues, we present cut-based and neural methods for chapter segmentation, achieving an F1-score of 0.453 on the challenging task of exact break prediction over book-length documents. Finally, we reveal interesting historical trends in the chapter structure of novels.