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Nov 4

DR Pixel: Page-Native Deep Research with Vision-Language Models

Complex documents such as scientific papers contain rich information in tables, figures, and equations; however, existing deep research (DR) agents typically reduce papers to OCR-extracted text. We instead ask whether vision-language models (VLMs) can enable page-native deep research: directly retrieving and reasoning over rendered document page images. We introduce DR Pixel, the first open-source end-to-end multimodal DR agent that uses rendered page images as its sole retrieval and reasoning unit, operating over a corpus of 1.06M pages. To evaluate this setting, we construct DRPixelBench, a benchmark on scientific papers requiring reasoning over text, figures, tables, and equations. Surprisingly, page-native DR already works well without training, outperforming OCR-based baselines across state-of-the-art models like GPT-5.4, Gemini-3.5-Flash, and Qwen3.6-27B, while requiring fewer tool calls. We next turn to DR training. A key challenge is that teacher trajectories for agentic supervised finetuning are noisy, mixing critical reasoning and action steps with redundant or failed attempts. To address this, we introduce counterfactual credit reweighting, a fine-grained credit assignment method that weights individual reasoning and action steps by their counterfactual contribution to the final answer. Our training improves retrieval recall by about 15 points and final accuracy by over 10 points on DRPixelBench, and likewise outperforms the untrained baseline on four existing benchmarks. On out-of-distribution ViDoRe-V3, DR Pixel comes within 1.8 points of an oracle that is given the gold pages directly. Our results suggest that the conventional OCR-then-retrieve pipeline is not only unnecessary but suboptimal: directly retrieving and reasoning over visual document pages makes complex DR both more effective and more efficient.

Lesion-aware network for diabetic retinopathy diagnosis

Deep learning brought boosts to auto diabetic retinopathy (DR) diagnosis, thus, greatly helping ophthalmologists for early disease detection, which contributes to preventing disease deterioration that may eventually lead to blindness. It has been proved that convolutional neural network (CNN)-aided lesion identifying or segmentation benefits auto DR screening. The key to fine-grained lesion tasks mainly lies in: (1) extracting features being both sensitive to tiny lesions and robust against DR-irrelevant interference, and (2) exploiting and re-using encoded information to restore lesion locations under extremely imbalanced data distribution. To this end, we propose a CNN-based DR diagnosis network with attention mechanism involved, termed lesion-aware network, to better capture lesion information from imbalanced data. Specifically, we design the lesion-aware module (LAM) to capture noise-like lesion areas across deeper layers, and the feature-preserve module (FPM) to assist shallow-to-deep feature fusion. Afterward, the proposed lesion-aware network (LANet) is constructed by embedding the LAM and FPM into the CNN decoders for DR-related information utilization. The proposed LANet is then further extended to a DR screening network by adding a classification layer. Through experiments on three public fundus datasets with pixel-level annotations, our method outperforms the mainstream methods with an area under curve of 0.967 in DR screening, and increases the overall average precision by 7.6%, 2.1%, and 1.2% in lesion segmentation on three datasets. Besides, the ablation study validates the effectiveness of the proposed sub-modules.

  • 5 authors
·
Aug 13, 2024

MedPixel: A Unified Pixel-Language Model for Medical Reasoning and Segmentation

Reliable medical image understanding requires models to connect clinical language and visual reasoning with pixel-level grounding. Yet medical vision-language models often lack precise localization, whereas medical segmenters typically rely on explicit target categories or precise spatial prompts. This divide is reinforced by a supervision mismatch: segmentation datasets provide precise masks but little language supervision, whereas medical vision-language data rarely pair language with dense spatial annotations. To address this gap, we present MedPixel, a unified medical pixel-language model built around a shared language--mask interface. To provide scalable supervision, we introduce MedPLG-440K, comprising approximately 440K pixel-language task samples constructed through a clinically motivated synthesis process without external LLM annotation. MedPixel is trained with joint multi-task supervised fine-tuning followed by Pixel-Level Preference Optimization, which uses ground-truth masks as offline verifiers to derive response preferences from mask quality. MedPixel supports a broad spectrum of tasks spanning explicit grounding, implicit reasoning, spatial interaction, grounded explanation, and medical VQA. Across this task spectrum, MedPixel achieves strong performance in both pixel-level prediction and response generation, together with effective zero-shot transfer to external grounding benchmarks and robustness to imperfect spatial prompts. Code and model checkpoints will be released at https://github.com/yhy-whu/Medpixel.

  • 8 authors
·
Aug 9