Daily Papers

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address these challenges, we propose a novel chain-based clinical reasoning framework, called DxChain, which transforms the diagnostic workflow into an iterative process by mirroring a clinician's cognitive trajectory that consists of "Memory Anchoring", "Navigation" and "Verification" phases. DxChain introduces three key methodological innovations to elicit the potential of LLM: (i) a Profile-Then-Plan paradigm to mitigate cold-start hallucinations by establishing a panoramic patient baseline, (ii) a Medical Tree-of-Thoughts (Med-ToT) algorithm for strategic look ahead planning and resource aware navigation, and (iii) a Dialectical Diagnostic Verification procedure utilizing "Angel-Devil" adversarial debates to resolve complex evidence conflicts. Evaluated on two real world benchmarks, MIMIC-IV-Ext Cardiac Disease and MIMIC-IV-Ext CDM, DxChain achieves state-of-the-art performances in both diagnostic accuracy and logical consistency, offering a modular and reliable architecture for next-generation clinical AI. The code is at https://anonymous.4open.science/r/Dx-Chain.

Vision Language Models (VLMs) are increasingly used for tasks like medical report generation and visual question answering. However, fluent diagnostic text does not guarantee safe visual understanding. In clinical practice, interpretation begins with pre-diagnostic sanity checks: verifying that the input is valid to read (correct modality and anatomy, plausible viewpoint and orientation, and no obvious integrity violations). Existing benchmarks largely assume this step is solved, and therefore miss a critical failure mode: a model can produce plausible narratives even when the input is inconsistent or invalid. We introduce MedObvious, a 1,880-task benchmark that isolates input validation as a set-level consistency capability over small multi-panel image sets: the model must identify whether any panel violates expected coherence. MedObvious spans five progressive tiers, from basic orientation/modality mismatches to clinically motivated anatomy/viewpoint verification and triage-style cues, and includes five evaluation formats to test robustness across interfaces. Evaluating 17 different VLMs, we find that sanity checking remains unreliable: several models hallucinate anomalies on normal (negative-control) inputs, performance degrades when scaling to larger image sets, and measured accuracy varies substantially between multiple-choice and open-ended settings. These results show that pre-diagnostic verification remains unsolved for medical VLMs and should be treated as a distinct, safety-critical capability before deployment.

Assessing scientific claims requires identifying, extracting, and reasoning with multimodal data expressed in information-rich figures in scientific literature. Despite the large body of work in scientific QA, figure captioning, and other multimodal reasoning tasks over chart-based data, there are no readily usable multimodal benchmarks that directly test claim verification abilities. To remedy this gap, we introduce a new benchmark MuSciClaims accompanied by diagnostics tasks. We automatically extract supported claims from scientific articles, which we manually perturb to produce contradicted claims. The perturbations are designed to test for a specific set of claim verification capabilities. We also introduce a suite of diagnostic tasks that help understand model failures. Our results show most vision-language models are poor (~0.3-0.5 F1), with even the best model only achieving 0.72 F1. They are also biased towards judging claims as supported, likely misunderstanding nuanced perturbations within the claims. Our diagnostics show models are bad at localizing correct evidence within figures, struggle with aggregating information across modalities, and often fail to understand basic components of the figure.

Verifying scientific claims presents a significantly greater challenge than verifying political or news-related claims. Unlike the relatively broad audience for political claims, the users of scientific claim verification systems can vary widely, ranging from researchers testing specific hypotheses to everyday users seeking information on a medication. Additionally, the evidence for scientific claims is often highly complex, involving technical terminology and intricate domain-specific concepts that require specialized models for accurate verification. Despite considerable interest from the research community, there is a noticeable lack of large-scale scientific claim verification datasets to benchmark and train effective models. To bridge this gap, we introduce two large-scale datasets, SciClaimHunt and SciClaimHunt_Num, derived from scientific research papers. We propose several baseline models tailored for scientific claim verification to assess the effectiveness of these datasets. Additionally, we evaluate models trained on SciClaimHunt and SciClaimHunt_Num against existing scientific claim verification datasets to gauge their quality and reliability. Furthermore, we conduct human evaluations of the claims in proposed datasets and perform error analysis to assess the effectiveness of the proposed baseline models. Our findings indicate that SciClaimHunt and SciClaimHunt_Num serve as highly reliable resources for training models in scientific claim verification.

Claim verification is critical for enhancing digital literacy. However, the state-of-the-art single-LLM methods struggle with complex claim verification that involves multi-faceted evidences. Inspired by real-world fact-checking practices, we propose DebateCV, the first claim verification framework that adopts a debate-driven methodology using multiple LLM agents. In our framework, two Debaters take opposing stances on a claim and engage in multi-round argumentation, while a Moderator evaluates the arguments and renders a verdict with justifications. To further improve the performance of the Moderator, we introduce a novel post-training strategy that leverages synthetic debate data generated by the zero-shot DebateCV, effectively addressing the scarcity of real-world debate-driven claim verification data. Experimental results show that our method outperforms existing claim verification methods under varying levels of evidence quality. Our code and dataset are publicly available at https://anonymous.4open.science/r/DebateCV-6781.

Language models (LMs) are widely used by an increasing number of users, underscoring the challenge of maintaining factuality across a broad range of topics. We first present VERIFY (Verification and Evidence RetrIeval for FactualitY evaluation), a pipeline to evaluate LMs' factuality in real-world user interactions. VERIFY considers the verifiability of LM-generated content and categorizes content units as supported, unsupported, or undecidable based on the retrieved evidence from the Web. Importantly, factuality judgment by VERIFY correlates better with human evaluations than existing methods. Using VERIFY, we identify "hallucination prompts" across diverse topics, i.e., those eliciting the highest rates of incorrect and inconclusive LM responses. These prompts form FactBench, a dataset of 1K prompts across 150 fine-grained topics. Our dataset captures emerging factuality challenges in real-world LM interactions and can be regularly updated with new prompts. We benchmark widely-used LMs from GPT, Gemini, and Llama3.1 family on FactBench, yielding the following key findings: (i) Proprietary models exhibit better factuality, with performance declining from Easy to Hard hallucination prompts. (ii) Llama3.1-405B-Instruct shows comparable or lower factual accuracy than Llama3.1-70B-Instruct across all evaluation methods due to its higher subjectivity that leads to more content labeled as undecidable. (iii) Gemini1.5-Pro shows a significantly higher refusal rate, with over-refusal in 25% of cases. Our code and data are publicly available at https://huggingface.co/spaces/launch/factbench.

Factual hallucination remains a central challenge for large language models (LLMs). Existing mitigation approaches primarily rely on either external post-hoc verification or mapping uncertainty directly to abstention during fine-tuning, often resulting in overly conservative behavior. We propose VeriFY, a training-time framework that teaches LLMs to reason about factual uncertainty through consistency-based self-verification. VeriFY augments training with structured verification traces that guide the model to produce an initial answer, generate and answer a probing verification query, issue a consistency judgment, and then decide whether to answer or abstain. To address the risk of reinforcing hallucinated content when training on augmented traces, we introduce a stage-level loss masking approach that excludes hallucinated answer stages from the training objective while preserving supervision over verification behavior. Across multiple model families and scales, VeriFY reduces factual hallucination rates by 9.7 to 53.3 percent, with only modest reductions in recall (0.4 to 5.7 percent), and generalizes across datasets when trained on a single source. The source code, training data, and trained model checkpoints will be released upon acceptance.

Current evaluation of mathematical reasoning in language models relies primarily on answer accuracy, potentially masking fundamental failures in logical computation. We introduce a diagnostic framework that distinguishes genuine mathematical reasoning from superficial pattern matching through four complementary axes: forward-backward consistency, transitivity coverage, counterfactual sensitivity, and perturbation robustness. Through a case study applying this framework to Qwen3-0.6B on the MenatQA dataset, we reveal a striking disconnect between surface performance and reasoning fidelity. While the model achieves reasonable answer accuracy (70%+), it demonstrates poor backward consistency (15%), limited transitivity coverage (32.2%), and brittle sensitivity to perturbations. Our diagnostics expose reasoning failures invisible to traditional accuracy metrics, suggesting that this small model relies heavily on pattern matching rather than genuine logical computation. While our empirical findings are based on a single 600M-parameter model, the diagnostic framework itself is model-agnostic and generalizable. We release our evaluation protocols to enable the research community to assess reasoning fidelity across different model scales and architectures, moving beyond surface-level accuracy toward verifiable mathematical reasoning.

Verifying complex political claims is a challenging task, especially when politicians use various tactics to subtly misrepresent the facts. Automatic fact-checking systems fall short here, and their predictions like "half-true" are not very useful in isolation, since we have no idea which parts of the claim are true and which are not. In this work, we focus on decomposing a complex claim into a comprehensive set of yes-no subquestions whose answers influence the veracity of the claim. We present ClaimDecomp, a dataset of decompositions for over 1000 claims. Given a claim and its verification paragraph written by fact-checkers, our trained annotators write subquestions covering both explicit propositions of the original claim and its implicit facets, such as asking about additional political context that changes our view of the claim's veracity. We study whether state-of-the-art models can generate such subquestions, showing that these models generate reasonable questions to ask, but predicting the comprehensive set of subquestions from the original claim without evidence remains challenging. We further show that these subquestions can help identify relevant evidence to fact-check the full claim and derive the veracity through their answers, suggesting that they can be useful pieces of a fact-checking pipeline.

Fact verification aims to automatically probe the veracity of a claim based on several pieces of evidence. Existing works are always engaging in the accuracy improvement, let alone the explainability, a critical capability of fact verification system. Constructing an explainable fact verification system in a complex multi-hop scenario is consistently impeded by the absence of a relevant high-quality dataset. Previous dataset either suffer from excessive simplification or fail to incorporate essential considerations for explainability. To address this, we present EX-FEVER, a pioneering dataset for multi-hop explainable fact verification. With over 60,000 claims involving 2-hop and 3-hop reasoning, each is created by summarizing and modifying information from hyperlinked Wikipedia documents. Each instance is accompanied by a veracity label and an explanation that outlines the reasoning path supporting the veracity classification. Additionally, we demonstrate a novel baseline system on our EX-FEVER dataset, showcasing document retrieval, explanation generation, and claim verification and observe that existing fact verification models trained on previous datasets struggle to perform well on our dataset. Furthermore, we highlight the potential of utilizing Large Language Models in the fact verification task. We hope our dataset could make a significant contribution by providing ample opportunities to explore the integration of natural language explanations in the domain of fact verification.

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios. Specifically, current LLMs suffer from three critical limitations: (1) generating hallucinated medical content due to weak grounding in verified knowledge, (2) asking redundant or inefficient questions rather than discriminative ones that hinder diagnostic progress, and (3) losing coherence over multi-turn dialogues, leading to contradictory or inconsistent conclusions. To address these challenges, we propose MedKGI, a diagnostic framework grounded in clinical practices. MedKGI integrates a medical knowledge graph (KG) to constrain reasoning to validated medical ontologies, selects questions based on information gain to maximize diagnostic efficiency, and adopts an OSCE-format structured state to maintain consistent evidence tracking across turns. Experiments on clinical benchmarks show that MedKGI outperforms strong LLM baselines in both diagnostic accuracy and inquiry efficiency, improving dialogue efficiency by 30% on average while maintaining state-of-the-art accuracy.

Large language models have achieved strong performance on medical reasoning benchmarks, yet their deployment in clinical settings demands rigorous verification to ensure factual accuracy. While reward models offer a scalable approach for reasoning trace verification, existing methods face two limitations: they produce only scalar reward values without explicit justification, and they rely on single-pass retrieval that precludes adaptive knowledge access as verification unfolds. We introduce method, an agentic framework that addresses these limitations by training medical reasoning verifiers to iteratively query external medical corpora during evaluation. Our approach combines tool-augmented verification with an iterative reinforcement learning paradigm that requires only trace-level supervision, alongside an adaptive curriculum mechanism that dynamically adjusts training data distribution. Across four medical reasoning benchmarks, method achieves substantial gains over existing methods, improving MedQA accuracy by 23.5% and MedXpertQA by 32.0% relative to the base generator in particular. Crucially, method demonstrates an 8times reduction in sampling budget requirement compared to prior reward model baselines. These findings establish that grounding verification in dynamically retrieved evidence offers a principled path toward more reliable medical reasoning systems.

Assessing whether an article supports an assertion is essential for hallucination detection and claim verification. While large language models (LLMs) have the potential to automate this task, achieving strong performance requires frontier models such as GPT-5 that are prohibitively expensive to deploy at scale. To efficiently perform biomedical evidence attribution, we present Med-V1, a family of small language models with only three billion parameters. Trained on high-quality synthetic data newly developed in this study, Med-V1 substantially outperforms (+27.0% to +71.3%) its base models on five biomedical benchmarks unified into a verification format. Despite its smaller size, Med-V1 performs comparably to frontier LLMs such as GPT-5, along with high-quality explanations for its predictions. We use Med-V1 to conduct a first-of-its-kind use case study that quantifies hallucinations in LLM-generated answers under different citation instructions. Results show that the format instruction strongly affects citation validity and hallucination, with GPT-5 generating more claims but exhibiting hallucination rates similar to GPT-4o. Additionally, we present a second use case showing that Med-V1 can automatically identify high-stakes evidence misattributions in clinical practice guidelines, revealing potentially negative public health impacts that are otherwise challenging to identify at scale. Overall, Med-V1 provides an efficient and accurate lightweight alternative to frontier LLMs for practical and real-world applications in biomedical evidence attribution and verification tasks. Med-V1 is available at https://github.com/ncbi-nlp/Med-V1.

Seeking health-related advice on the internet has become a common practice in the digital era. Determining the trustworthiness of medical claims found online and finding appropriate evidence for this information is increasingly challenging. Fact-checking has emerged as an approach to assess the veracity of factual claims using evidence from credible knowledge sources. To help advance the automation of this task, in this paper, we introduce a novel dataset of 750 health-related claims, labeled for veracity by medical experts and backed with evidence from appropriate clinical studies. We provide an analysis of the dataset, highlighting its characteristics and challenges. The dataset can be used for Machine Learning tasks related to automated fact-checking such as evidence retrieval, veracity prediction, and explanation generation. For this purpose, we provide baseline models based on different approaches, examine their performance, and discuss the findings.

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is essential for assessing whether diagnostic reasoning is reliable and clinically grounded. However, debugging medical LLMs remains difficult. First, developers often lack sufficient medical domain expertise to interpret model errors in clinically meaningful terms. Second, models can fail across a large and diverse set of instances involving different input types, tasks, and reasoning steps, making it challenging for developers to prioritize which errors deserve focused inspection. Third, developers struggle to identify recurring error patterns across cases, as existing debugging practices are largely instance-centric and rely on manual inspection of isolated failures. To address these challenges, we present VeriLLMed, a visual analytics system that integrates external biomedical knowledge to audit and debug medical LLM diagnostic reasoning. VeriLLMed transforms model outputs into comparable reasoning paths, constructs knowledge graph-grounded reference paths, and identifies three recurring classes of diagnosis errors: relation errors, branch errors, and missing errors. Case studies and expert evaluation demonstrate that VeriLLMed helps developers identify clinically implausible reasoning and generate actionable insights that can inform the improvement of medical LLMs.

The age of social media is flooded with Internet memes, necessitating a clear grasp and effective identification of harmful ones. This task presents a significant challenge due to the implicit meaning embedded in memes, which is not explicitly conveyed through the surface text and image. However, existing harmful meme detection methods do not present readable explanations that unveil such implicit meaning to support their detection decisions. In this paper, we propose an explainable approach to detect harmful memes, achieved through reasoning over conflicting rationales from both harmless and harmful positions. Specifically, inspired by the powerful capacity of Large Language Models (LLMs) on text generation and reasoning, we first elicit multimodal debate between LLMs to generate the explanations derived from the contradictory arguments. Then we propose to fine-tune a small language model as the debate judge for harmfulness inference, to facilitate multimodal fusion between the harmfulness rationales and the intrinsic multimodal information within memes. In this way, our model is empowered to perform dialectical reasoning over intricate and implicit harm-indicative patterns, utilizing multimodal explanations originating from both harmless and harmful arguments. Extensive experiments on three public meme datasets demonstrate that our harmful meme detection approach achieves much better performance than state-of-the-art methods and exhibits a superior capacity for explaining the meme harmfulness of the model predictions.

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis requires both the outcome and the reasoning process to be accurate. Currently, widely used medical benchmarks like MedQA and MMLU assess only accuracy in the final answer, overlooking the quality and faithfulness of the clinical reasoning process. To address this limitation, we introduce MedCaseReasoning, the first open-access dataset for evaluating LLMs on their ability to align with clinician-authored diagnostic reasoning. The dataset includes 14,489 diagnostic question-and-answer cases, each paired with detailed reasoning statements derived from open-access medical case reports. We evaluate state-of-the-art reasoning LLMs on MedCaseReasoning and find significant shortcomings in their diagnoses and reasoning: for instance, the top-performing open-source model, DeepSeek-R1, achieves only 48% 10-shot diagnostic accuracy and mentions only 64% of the clinician reasoning statements (recall). However, we demonstrate that fine-tuning LLMs on the reasoning traces derived from MedCaseReasoning significantly improves diagnostic accuracy and clinical reasoning recall by an average relative gain of 29% and 41%, respectively. The open-source dataset, code, and models are available at https://github.com/kevinwu23/Stanford-MedCaseReasoning.

Large language models (LLMs) have shown significant potential in scientific disciplines such as biomedicine, particularly in hypothesis generation, where they can analyze vast literature, identify patterns, and suggest research directions. However, a key challenge lies in evaluating the truthfulness of generated hypotheses, as verifying their accuracy often requires substantial time and resources. Additionally, the hallucination problem in LLMs can lead to the generation of hypotheses that appear plausible but are ultimately incorrect, undermining their reliability. To facilitate the systematic study of these challenges, we introduce TruthHypo, a benchmark for assessing the capabilities of LLMs in generating truthful biomedical hypotheses, and KnowHD, a knowledge-based hallucination detector to evaluate how well hypotheses are grounded in existing knowledge. Our results show that LLMs struggle to generate truthful hypotheses. By analyzing hallucinations in reasoning steps, we demonstrate that the groundedness scores provided by KnowHD serve as an effective metric for filtering truthful hypotheses from the diverse outputs of LLMs. Human evaluations further validate the utility of KnowHD in identifying truthful hypotheses and accelerating scientific discovery. Our data and source code are available at https://github.com/Teddy-XiongGZ/TruthHypo.

Large language models (LLMs) have shown substantial capacity for generating fluent, contextually appropriate responses. However, they can produce hallucinated outputs, especially when a user query includes one or more false premises-claims that contradict established facts. Such premises can mislead LLMs into offering fabricated or misleading details. Existing approaches include pretraining, fine-tuning, and inference-time techniques that often rely on access to logits or address hallucinations after they occur. These methods tend to be computationally expensive, require extensive training data, or lack proactive mechanisms to prevent hallucination before generation, limiting their efficiency in real-time applications. We propose a retrieval-based framework that identifies and addresses false premises before generation. Our method first transforms a user's query into a logical representation, then applies retrieval-augmented generation (RAG) to assess the validity of each premise using factual sources. Finally, we incorporate the verification results into the LLM's prompt to maintain factual consistency in the final output. Experiments show that this approach effectively reduces hallucinations, improves factual accuracy, and does not require access to model logits or large-scale fine-tuning.

Fact-checking is the task of verifying the veracity of claims by assessing their assertions against credible evidence. The vast majority of fact-checking studies focus exclusively on political claims. Very little research explores fact-checking for other topics, specifically subject matters for which expertise is required. We present the first study of explainable fact-checking for claims which require specific expertise. For our case study we choose the setting of public health. To support this case study we construct a new dataset PUBHEALTH of 11.8K claims accompanied by journalist crafted, gold standard explanations (i.e., judgments) to support the fact-check labels for claims. We explore two tasks: veracity prediction and explanation generation. We also define and evaluate, with humans and computationally, three coherence properties of explanation quality. Our results indicate that, by training on in-domain data, gains can be made in explainable, automated fact-checking for claims which require specific expertise.

Evidence-grounded reasoning requires more than attaching retrieved text to a prediction: a model should make decisions that depend on whether the provided evidence supports the target claim. In practice, this often fails because supervision is weak, evidence is only loosely tied to the claim, and evaluation does not test evidence dependence directly. We introduce case-grounded evidence verification, a general framework in which a model receives a local case context, external evidence, and a structured claim, and must decide whether the evidence supports the claim for that case. Our key contribution is a supervision construction procedure that generates explicit support examples together with semantically controlled non-support examples, including counterfactual wrong-state and topic-related negatives, without manual evidence annotation. We instantiate the framework in radiology and train a standard verifier on the resulting support task. The learned verifier substantially outperforms both case-only and evidence-only baselines, remains strong under correct evidence, and collapses when evidence is removed or swapped, indicating genuine evidence dependence. This behavior transfers across unseen evidence articles and an external case distribution, though performance degrades under evidence-source shift and remains sensitive to backbone choice. Overall, the results suggest that a major bottleneck in evidence grounding is not only model capacity, but the lack of supervision that encodes the causal role of evidence.

Traditionally, AI research in medical diagnosis has largely centered on image analysis. While this has led to notable advancements, the absence of patient-reported symptoms continues to hinder diagnostic accuracy. To address this, we propose a Pre-Consultation Dialogue Framework (PCDF) that mimics real-world diagnostic procedures, where doctors iteratively query patients before reaching a conclusion. Specifically, we simulate diagnostic dialogues between two vision-language models (VLMs): a DocVLM, which generates follow-up questions based on the image and dialogue history, and a PatientVLM, which responds using a symptom profile derived from the ground-truth diagnosis. We additionally conducted a small-scale clinical validation of the synthetic symptoms generated by our framework, with licensed clinicians confirming their clinical relevance, symptom coverage, and overall realism. These findings indicate that the resulting DocVLM-PatientVLM interactions form coherent, multi-turn consultations paired with images and diagnoses, which we then use to fine-tune the DocVLM. This dialogue-based supervision leads to substantial gains over image-only training, highlighting the value of realistic symptom elicitation for diagnosis.

We introduce SimpleQA Verified, a 1,000-prompt benchmark for evaluating Large Language Model (LLM) short-form factuality based on OpenAI's SimpleQA. It addresses critical limitations in OpenAI's benchmark, including noisy and incorrect labels, topical biases, and question redundancy. SimpleQA Verified was created through a rigorous multi-stage filtering process involving de-duplication, topic balancing, and source reconciliation to produce a more reliable and challenging evaluation set, alongside improvements in the autorater prompt. On this new benchmark, Gemini 2.5 Pro achieves a state-of-the-art F1-score of 55.6, outperforming other frontier models, including GPT-5. This work provides the research community with a higher-fidelity tool to track genuine progress in parametric model factuality and to mitigate hallucinations. The benchmark dataset, evaluation code, and leaderboard are available at: https://www.kaggle.com/benchmarks/deepmind/simpleqa-verified.

Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure mode: instability in early evidence interpretation precedes hallucination, creating branching reasoning trajectories that cascade into globally inconsistent conclusions. This highlights the need for clinical reasoning agents that constrain stochasticity and hallucination while producing auditable decision flows. We introduce MedMMV, a controllable multimodal multi-agent framework for reliable and verifiable clinical reasoning. MedMMV stabilizes reasoning through diversified short rollouts, grounds intermediate steps in a structured evidence graph under the supervision of a Hallucination Detector, and aggregates candidate paths with a Combined Uncertainty scorer. On six medical benchmarks, MedMMV improves accuracy by up to 12.7% and, more critically, demonstrates superior reliability. Blind physician evaluations confirm that MedMMV substantially increases reasoning truthfulness without sacrificing informational content. By controlling instability through a verifiable, multi-agent process, our framework provides a robust path toward deploying trustworthy AI systems in high-stakes domains like clinical decision support.

In this paper we introduce a new publicly available dataset for verification against textual sources, FEVER: Fact Extraction and VERification. It consists of 185,445 claims generated by altering sentences extracted from Wikipedia and subsequently verified without knowledge of the sentence they were derived from. The claims are classified as Supported, Refuted or NotEnoughInfo by annotators achieving 0.6841 in Fleiss kappa. For the first two classes, the annotators also recorded the sentence(s) forming the necessary evidence for their judgment. To characterize the challenge of the dataset presented, we develop a pipeline approach and compare it to suitably designed oracles. The best accuracy we achieve on labeling a claim accompanied by the correct evidence is 31.87%, while if we ignore the evidence we achieve 50.91%. Thus we believe that FEVER is a challenging testbed that will help stimulate progress on claim verification against textual sources.

Clinical diagnosis is critical in medical practice, typically requiring a continuous and evolving process that includes primary diagnosis, differential diagnosis, and final diagnosis. However, most existing clinical diagnostic tasks are single-step processes, which does not align with the complex multi-step diagnostic procedures found in real-world clinical settings. In this paper, we propose a multi-step diagnostic task and annotate a clinical diagnostic dataset (MSDiagnosis). This dataset includes primary diagnosis, differential diagnosis, and final diagnosis questions. Additionally, we propose a novel and effective framework. This framework combines forward inference, backward inference, reflection, and refinement, enabling the LLM to self-evaluate and adjust its diagnostic results. To assess the effectiveness of our proposed method, we design and conduct extensive experiments. The experimental results demonstrate the effectiveness of the proposed method. We also provide a comprehensive experimental analysis and suggest future research directions for this task.

As Large Language Models (LLMs) become more pervasive across various users and scenarios, identifying potential issues when using these models becomes essential. Examples of such issues include: bias, inconsistencies, and hallucination. Although auditing the LLM for these problems is often warranted, such a process is neither easy nor accessible for most. An effective method is to probe the LLM using different versions of the same question. This could expose inconsistencies in its knowledge or operation, indicating potential for bias or hallucination. However, to operationalize this auditing method at scale, we need an approach to create those probes reliably and automatically. In this paper we propose the LLMAuditor framework which is an automatic, and scalable solution, where one uses a different LLM along with human-in-the-loop (HIL). This approach offers verifiability and transparency, while avoiding circular reliance on the same LLM, and increasing scientific rigor and generalizability. Specifically, LLMAuditor includes two phases of verification using humans: standardized evaluation criteria to verify responses, and a structured prompt template to generate desired probes. A case study using questions from the TruthfulQA dataset demonstrates that we can generate a reliable set of probes from one LLM that can be used to audit inconsistencies in a different LLM. This process is enhanced by our structured prompt template with HIL, which not only boosts the reliability of our approach in auditing but also yields the delivery of less hallucinated results. The novelty of our research stems from the development of a comprehensive, general-purpose framework that includes a HIL verified prompt template for auditing responses generated by LLMs.

Claim verification is essential in combating misinformation, and large language models (LLMs) have recently emerged in this area as powerful tools for assessing the veracity of claims using external knowledge. Existing LLM-based methods for claim verification typically adopt a Decompose-Then-Verify paradigm, which involves decomposing complex claims into several independent sub-claims and verifying each sub-claim separately. However, this paradigm often introduces errors during the claim decomposition process. To mitigate these errors, we propose to develop the Chain-of-Thought (CoT)-Verify paradigm, which leverages LLM reasoning methods to generate CoT-verification paths for the original complex claim without requiring decompositions into sub-claims and separate verification stages. The CoT-Verify paradigm allows us to propose a natural fine-tuning method called Reasoning-CV to enhance the verification capabilities in LLMs. Reasoning-CV includes a supervised fine-tuning (SFT) stage and a self-improvement direct preference optimization (DPO) stage. Utilizing only an 8B pre-trained LLM, Reasoning-CV demonstrates superior knowledge-assisted claim verification performances compared to existing Decompose-Then-Verify methods, as well as powerful black-box LLMs such as GPT-4o+CoT and o1-preview. Our code is available.

The adoption of Large Language Models (LLMs) in scientific writing promises efficiency but risks introducing informational entropy. While "hallucinated papers" are a known artifact, the systematic degradation of valid citation chains remains unquantified. We conducted a forensic audit of 50 recent survey papers in Artificial Intelligence (N=5,514 citations) published between September 2024 and January 2026. We utilized a hybrid verification pipeline combining DOI resolution, Crossref metadata analysis, Semantic Scholar queries, and fuzzy text matching to distinguish between formatting errors ("Sloppiness") and verifiable non-existence ("Phantoms). We detect a persistent 17.0% Phantom Rate -- citations that cannot be resolved to any digital object despite aggressive forensic recovery. Diagnostic categorization reveals three distinct failure modes: pure hallucinations (5.1%), hallucinated identifiers with valid titles (16.4%), and parsing-induced matching failures (78.5%). Longitudinal analysis reveals a flat trend (+0.07 pp/month), suggesting that high-entropy citation practices have stabilized as an endemic feature of the field. The scientific citation graph in AI survey literature exhibits "link rot" at scale. This suggests a mechanism where AI tools act as "lazy research assistants," retrieving correct titles but hallucinating metadata, thereby severing the digital chain of custody required for reproducible science.

Claim verification can be a challenging task. In this paper, we present a method to enhance the robustness and reasoning capabilities of automated claim verification through the extraction of short facts from evidence. Our novel approach, FactDetect, leverages Large Language Models (LLMs) to generate concise factual statements from evidence and label these facts based on their semantic relevance to the claim and evidence. The generated facts are then combined with the claim and evidence. To train a lightweight supervised model, we incorporate a fact-detection task into the claim verification process as a multitasking approach to improve both performance and explainability. We also show that augmenting FactDetect in the claim verification prompt enhances performance in zero-shot claim verification using LLMs. Our method demonstrates competitive results in the supervised claim verification model by 15% on the F1 score when evaluated for challenging scientific claim verification datasets. We also demonstrate that FactDetect can be augmented with claim and evidence for zero-shot prompting (AugFactDetect) in LLMs for verdict prediction. We show that AugFactDetect outperforms the baseline with statistical significance on three challenging scientific claim verification datasets with an average of 17.3% performance gain compared to the best performing baselines.

Fact verification systems typically assess whether a claim is supported by retrieved evidence, assuming that truthfulness depends solely on what is stated. However, many real-world claims are half-truths, factually correct yet misleading due to the omission of critical context. Existing models struggle with such cases, as they are not designed to reason about what is left unsaid. We introduce the task of half-truth detection, and propose PolitiFact-Hidden, a new benchmark with 15k political claims annotated with sentence-level evidence alignment and inferred claim intent. To address this challenge, we present TRACER, a modular re-assessment framework that identifies omission-based misinformation by aligning evidence, inferring implied intent, and estimating the causal impact of hidden content. TRACER can be integrated into existing fact-checking pipelines and consistently improves performance across multiple strong baselines. Notably, it boosts Half-True classification F1 by up to 16 points, highlighting the importance of modeling omissions for trustworthy fact verification.

Generative Large Language Models (LLMs) such as GPT-3 are capable of generating highly fluent responses to a wide variety of user prompts. However, LLMs are known to hallucinate facts and make non-factual statements which can undermine trust in their output. Existing fact-checking approaches either require access to token-level output probability distribution (which may not be available for systems such as ChatGPT) or external databases that are interfaced via separate, often complex, modules. In this work, we propose "SelfCheckGPT", a simple sampling-based approach that can be used to fact-check black-box models in a zero-resource fashion, i.e. without an external database. SelfCheckGPT leverages the simple idea that if a LLM has knowledge of a given concept, sampled responses are likely to be similar and contain consistent facts. However, for hallucinated facts, stochastically sampled responses are likely to diverge and contradict one another. We investigate this approach by using GPT-3 to generate passages about individuals from the WikiBio dataset, and manually annotate the factuality of the generated passages. We demonstrate that SelfCheckGPT can: i) detect non-factual and factual sentences; and ii) rank passages in terms of factuality. We compare our approach to several existing baselines and show that in sentence hallucination detection, our approach has AUC-PR scores comparable to grey-box methods, while SelfCheckGPT is best at passage factuality assessment.

Large language models (LLMs) are notorious for hallucinating, i.e., producing erroneous claims in their output. Such hallucinations can be dangerous, as occasional factual inaccuracies in the generated text might be obscured by the rest of the output being generally factual, making it extremely hard for the users to spot them. Current services that leverage LLMs usually do not provide any means for detecting unreliable generations. Here, we aim to bridge this gap. In particular, we propose a novel fact-checking and hallucination detection pipeline based on token-level uncertainty quantification. Uncertainty scores leverage information encapsulated in the output of a neural network or its layers to detect unreliable predictions, and we show that they can be used to fact-check the atomic claims in the LLM output. Moreover, we present a novel token-level uncertainty quantification method that removes the impact of uncertainty about what claim to generate on the current step and what surface form to use. Our method Claim Conditioned Probability (CCP) measures only the uncertainty of particular claim value expressed by the model. Experiments on the task of biography generation demonstrate strong improvements for CCP compared to the baselines for six different LLMs and three languages. Human evaluation reveals that the fact-checking pipeline based on uncertainty quantification is competitive with a fact-checking tool that leverages external knowledge.

Fact verification has attracted a lot of attention in the machine learning and natural language processing communities, as it is one of the key methods for detecting misinformation. Existing large-scale benchmarks for this task have focused mostly on textual sources, i.e. unstructured information, and thus ignored the wealth of information available in structured formats, such as tables. In this paper we introduce a novel dataset and benchmark, Fact Extraction and VERification Over Unstructured and Structured information (FEVEROUS), which consists of 87,026 verified claims. Each claim is annotated with evidence in the form of sentences and/or cells from tables in Wikipedia, as well as a label indicating whether this evidence supports, refutes, or does not provide enough information to reach a verdict. Furthermore, we detail our efforts to track and minimize the biases present in the dataset and could be exploited by models, e.g. being able to predict the label without using evidence. Finally, we develop a baseline for verifying claims against text and tables which predicts both the correct evidence and verdict for 18% of the claims.

Explaining Artificial Intelligence (AI) decisions is a major challenge nowadays in AI, in particular when applied to sensitive scenarios like medicine and law. However, the need to explain the rationale behind decisions is a main issue also for human-based deliberation as it is important to justify why a certain decision has been taken. Resident medical doctors for instance are required not only to provide a (possibly correct) diagnosis, but also to explain how they reached a certain conclusion. Developing new tools to aid residents to train their explanation skills is therefore a central objective of AI in education. In this paper, we follow this direction, and we present, to the best of our knowledge, the first multilingual dataset for Medical Question Answering where correct and incorrect diagnoses for a clinical case are enriched with a natural language explanation written by doctors. These explanations have been manually annotated with argument components (i.e., premise, claim) and argument relations (i.e., attack, support), resulting in the Multilingual CasiMedicos-Arg dataset which consists of 558 clinical cases in four languages (English, Spanish, French, Italian) with explanations, where we annotated 5021 claims, 2313 premises, 2431 support relations, and 1106 attack relations. We conclude by showing how competitive baselines perform over this challenging dataset for the argument mining task.

Large Language Models (LLMs) are increasingly deployed in enterprise applications, yet their reliability remains limited by hallucinations, i.e., confident but factually incorrect information. Existing detection approaches, such as SelfCheckGPT and MetaQA, primarily target standalone LLMs and do not address the unique challenges of Retrieval-Augmented Generation (RAG) systems, where responses must be consistent with retrieved evidence. We therefore present MetaRAG, a metamorphic testing framework for hallucination detection in Retrieval-Augmented Generation (RAG) systems. MetaRAG operates in a real-time, unsupervised, black-box setting, requiring neither ground-truth references nor access to model internals, making it suitable for proprietary and high-stakes domains. The framework proceeds in four stages: (1) decompose answers into atomic factoids, (2) generate controlled mutations of each factoid using synonym and antonym substitutions, (3) verify each variant against the retrieved context (synonyms are expected to be entailed and antonyms contradicted), and (4) aggregate penalties for inconsistencies into a response-level hallucination score. Crucially for identity-aware AI, MetaRAG localizes unsupported claims at the factoid span where they occur (e.g., pregnancy-specific precautions, LGBTQ+ refugee rights, or labor eligibility), allowing users to see flagged spans and enabling system designers to configure thresholds and guardrails for identity-sensitive queries. Experiments on a proprietary enterprise dataset illustrate the effectiveness of MetaRAG for detecting hallucinations and enabling trustworthy deployment of RAG-based conversational agents. We also outline a topic-based deployment design that translates MetaRAG's span-level scores into identity-aware safeguards; this design is discussed but not evaluated in our experiments.

Large language models (LLMs) are increasingly used in healthcare, but their reliability is heavily influenced by user-driven factors such as question phrasing and the completeness of clinical information. In this study, we examined how misinformation framing, source authority, model persona, and omission of key clinical details affect the diagnostic accuracy and reliability of LLM outputs. We conducted two experiments: one introducing misleading external opinions with varying assertiveness (perturbation test), and another removing specific categories of patient information (ablation test). Using public datasets (MedQA and Medbullets), we evaluated proprietary models (GPT-4o, Claude 3.5 Sonnet, Claude 3.5 Haiku, Gemini 1.5 Pro, Gemini 1.5 Flash) and open-source models (LLaMA 3 8B, LLaMA 3 Med42 8B, DeepSeek R1 8B). All models were vulnerable to user-driven misinformation, with proprietary models especially affected by definitive and authoritative language. Assertive tone had the greatest negative impact on accuracy. In the ablation test, omitting physical exam findings and lab results caused the most significant performance drop. Although proprietary models had higher baseline accuracy, their performance declined sharply under misinformation. These results highlight the need for well-structured prompts and complete clinical context. Users should avoid authoritative framing of misinformation and provide full clinical details, especially for complex cases.

We introduce scientific claim verification, a new task to select abstracts from the research literature containing evidence that SUPPORTS or REFUTES a given scientific claim, and to identify rationales justifying each decision. To study this task, we construct SciFact, a dataset of 1.4K expert-written scientific claims paired with evidence-containing abstracts annotated with labels and rationales. We develop baseline models for SciFact, and demonstrate that simple domain adaptation techniques substantially improve performance compared to models trained on Wikipedia or political news. We show that our system is able to verify claims related to COVID-19 by identifying evidence from the CORD-19 corpus. Our experiments indicate that SciFact will provide a challenging testbed for the development of new systems designed to retrieve and reason over corpora containing specialized domain knowledge. Data and code for this new task are publicly available at https://github.com/allenai/scifact. A leaderboard and COVID-19 fact-checking demo are available at https://scifact.apps.allenai.org.

We explore uncertainty quantification in large language models (LLMs), with the goal to identify when uncertainty in responses given a query is large. We simultaneously consider both epistemic and aleatoric uncertainties, where the former comes from the lack of knowledge about the ground truth (such as about facts or the language), and the latter comes from irreducible randomness (such as multiple possible answers). In particular, we derive an information-theoretic metric that allows to reliably detect when only epistemic uncertainty is large, in which case the output of the model is unreliable. This condition can be computed based solely on the output of the model obtained simply by some special iterative prompting based on the previous responses. Such quantification, for instance, allows to detect hallucinations (cases when epistemic uncertainty is high) in both single- and multi-answer responses. This is in contrast to many standard uncertainty quantification strategies (such as thresholding the log-likelihood of a response) where hallucinations in the multi-answer case cannot be detected. We conduct a series of experiments which demonstrate the advantage of our formulation. Further, our investigations shed some light on how the probabilities assigned to a given output by an LLM can be amplified by iterative prompting, which might be of independent interest.

Chain-of-Thought (CoT) prompting has become the de facto method to elicit reasoning capabilities from large language models (LLMs). However, to mitigate hallucinations in CoT that are notoriously difficult to detect, current methods such as process reward models (PRMs) or self-consistency operate as opaque boxes and do not provide checkable evidence for their judgments, possibly limiting their effectiveness. To address this issue, we draw inspiration from the idea that "the gold standard for supporting a mathematical claim is to provide a proof". We propose a retrospective, step-aware formal verification framework Safe. Rather than assigning arbitrary scores, we strive to articulate mathematical claims in formal mathematical language Lean 4 at each reasoning step and provide formal proofs to identify hallucinations. We evaluate our framework Safe across multiple language models and various mathematical datasets, demonstrating a significant performance improvement while offering interpretable and verifiable evidence. We also propose FormalStep as a benchmark for step correctness theorem proving with 30,809 formal statements. To the best of our knowledge, our work represents the first endeavor to utilize formal mathematical language Lean 4 for verifying natural language content generated by LLMs, aligning with the reason why formal mathematical languages were created in the first place: to provide a robust foundation for hallucination-prone human-written proofs.

Artificial intelligence holds great promise for expanding access to expert medical knowledge and reasoning. However, most evaluations of language models rely on static vignettes and multiple-choice questions that fail to reflect the complexity and nuance of evidence-based medicine in real-world settings. In clinical practice, physicians iteratively formulate and revise diagnostic hypotheses, adapting each subsequent question and test to what they've just learned, and weigh the evolving evidence before committing to a final diagnosis. To emulate this iterative process, we introduce the Sequential Diagnosis Benchmark, which transforms 304 diagnostically challenging New England Journal of Medicine clinicopathological conference (NEJM-CPC) cases into stepwise diagnostic encounters. A physician or AI begins with a short case abstract and must iteratively request additional details from a gatekeeper model that reveals findings only when explicitly queried. Performance is assessed not just by diagnostic accuracy but also by the cost of physician visits and tests performed. We also present the MAI Diagnostic Orchestrator (MAI-DxO), a model-agnostic orchestrator that simulates a panel of physicians, proposes likely differential diagnoses and strategically selects high-value, cost-effective tests. When paired with OpenAI's o3 model, MAI-DxO achieves 80% diagnostic accuracy--four times higher than the 20% average of generalist physicians. MAI-DxO also reduces diagnostic costs by 20% compared to physicians, and 70% compared to off-the-shelf o3. When configured for maximum accuracy, MAI-DxO achieves 85.5% accuracy. These performance gains with MAI-DxO generalize across models from the OpenAI, Gemini, Claude, Grok, DeepSeek, and Llama families. We highlight how AI systems, when guided to think iteratively and act judiciously, can advance diagnostic precision and cost-effectiveness in clinical care.

Chest X-ray plays a central role in thoracic diagnosis, and its interpretation inherently requires multi-step, evidence-grounded reasoning. However, large vision-language models (LVLMs) often generate plausible responses that are not faithfully grounded in diagnostic evidence and provide limited visual evidence for verification, while also requiring costly retraining to support new diagnostic tasks, limiting their reliability and adaptability in clinical settings. To address these limitations, we present CXReasonAgent, a diagnostic agent that integrates a large language model (LLM) with clinically grounded diagnostic tools to perform evidence-grounded diagnostic reasoning using image-derived diagnostic and visual evidence. To evaluate these capabilities, we introduce CXReasonDial, a multi-turn dialogue benchmark with 1,946 dialogues across 12 diagnostic tasks, and show that CXReasonAgent produces faithfully grounded responses, enabling more reliable and verifiable diagnostic reasoning than LVLMs. These findings highlight the importance of integrating clinically grounded diagnostic tools, particularly in safety-critical clinical settings.

With the rise of generative AI, automated fact-checking methods to combat misinformation are becoming more and more important. However, factual claim detection, the first step in a fact-checking pipeline, suffers from two key issues that limit its scalability and generalizability: (1) inconsistency in definitions of the task and what a claim is, and (2) the high cost of manual annotation. To address (1), we review the definitions in related work and propose a unifying definition of factual claims that focuses on verifiability. To address (2), we introduce AFaCTA (Automatic Factual Claim deTection Annotator), a novel framework that assists in the annotation of factual claims with the help of large language models (LLMs). AFaCTA calibrates its annotation confidence with consistency along three predefined reasoning paths. Extensive evaluation and experiments in the domain of political speech reveal that AFaCTA can efficiently assist experts in annotating factual claims and training high-quality classifiers, and can work with or without expert supervision. Our analyses also result in PoliClaim, a comprehensive claim detection dataset spanning diverse political topics.

Faithfulness hallucinations are claims generated by a Large Language Model (LLM) not supported by contexts provided to the LLM. Lacking assessment standards, existing benchmarks focus on "factual statements" that rephrase source materials while overlooking "cognitive statements" that involve making inferences from the given context. Consequently, evaluating and detecting the hallucination of cognitive statements remains challenging. Inspired by how evidence is assessed in the legal domain, we design a rigorous framework to assess different levels of faithfulness of cognitive statements and introduce the CogniBench dataset where we reveal insightful statistics. To keep pace with rapidly evolving LLMs, we further develop an automatic annotation pipeline that scales easily across different models. This results in a large-scale CogniBench-L dataset, which facilitates training accurate detectors for both factual and cognitive hallucinations. We release our model and datasets at: https://github.com/FUTUREEEEEE/CogniBench

Studies have underscored how, regardless of the recent breakthrough and swift advances in AI research, even state-of-the-art Large Language models (LLMs) continue to struggle when performing logical and mathematical reasoning. The results seem to suggest that LLMs still work as (highly advanced) data pattern identifiers, scoring poorly when attempting to generalise and solve reasoning problems the models have never previously seen or that are not close to samples presented in their training data. To address this compelling concern, this paper makes use of the notion of critical questions from the literature on argumentation theory, focusing in particular on Toulmin's model of argumentation. We show that employing these critical questions can improve the reasoning capabilities of LLMs. By probing the rationale behind the models' reasoning process, the LLM can assess whether some logical mistake is occurring and correct it before providing the final reply to the user prompt. The underlying idea is drawn from the gold standard of any valid argumentative procedure: the conclusion is valid if it is entailed by accepted premises. Or, to paraphrase such Aristotelian principle in a real-world approximation, characterised by incomplete information and presumptive logic, the conclusion is valid if not proved otherwise. This approach successfully steers the models' output through a reasoning pipeline, resulting in better performance against the baseline and its Chain-of-Thought (CoT) implementation. To this end, an extensive evaluation of the proposed approach on the MT-Bench Reasoning and Math tasks across a range of LLMs is provided.

Given the growing influx of misinformation across news and social media, there is a critical need for systems that can provide effective real-time verification of news claims. Large language or multimodal model based verification has been proposed to scale up online policing mechanisms for mitigating spread of false and harmful content. While these can potentially reduce burden on human fact-checkers, such efforts may be hampered by foundation model training data becoming outdated. In this work, we test the limits of improving foundation model performance without continual updating through an initial study of knowledge transfer using either existing intra- and inter- domain benchmarks or explanations generated from large language models (LLMs). We evaluate on 12 public benchmarks for fact-checking and misinformation detection as well as two other tasks relevant to content moderation -- toxicity and stance detection. Our results on two recent multi-modal fact-checking benchmarks, Mocheg and Fakeddit, indicate that knowledge transfer strategies can improve Fakeddit performance over the state-of-the-art by up to 1.7% and Mocheg performance by up to 2.9%.

The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable their safe and effective deployment in real-world healthcare settings, it is urgently necessary to benchmark the diagnostic capabilities of current models systematically. Given the limitations of existing medical benchmarks in evaluating advanced diagnostic reasoning, we present DiagnosisArena, a comprehensive and challenging benchmark designed to rigorously assess professional-level diagnostic competence. DiagnosisArena consists of 1,113 pairs of segmented patient cases and corresponding diagnoses, spanning 28 medical specialties, deriving from clinical case reports published in 10 top-tier medical journals. The benchmark is developed through a meticulous construction pipeline, involving multiple rounds of screening and review by both AI systems and human experts, with thorough checks conducted to prevent data leakage. Our study reveals that even the most advanced reasoning models, o3-mini, o1, and DeepSeek-R1, achieve only 45.82%, 31.09%, and 17.79% accuracy, respectively. This finding highlights a significant generalization bottleneck in current large language models when faced with clinical diagnostic reasoning challenges. Through DiagnosisArena, we aim to drive further advancements in AIs diagnostic reasoning capabilities, enabling more effective solutions for real-world clinical diagnostic challenges. We provide the benchmark and evaluation tools for further research and development https://github.com/SPIRAL-MED/DiagnosisArena.

Large language models (LLMs) are becoming deeply embedded in human communication and decision-making, yet they inherit the ambiguity, bias, and lack of direct access to truth inherent in language itself. While their outputs are fluent, emotionally resonant, and coherent, they are generated through statistical prediction rather than grounded reasoning. This creates the risk of hallucination, responses that sound convincing but lack factual validity. Building on Geoffrey Hinton's observation that AI mirrors human intuition rather than reasoning, this paper argues that LLMs operationalize System 1 cognition at scale: fast, associative, and persuasive, but without reflection or falsification. To address this, we introduce the Rose-Frame, a three-dimensional framework for diagnosing cognitive and epistemic drift in human-AI interaction. The three axes are: (i) Map vs. Territory, which distinguishes representations of reality (epistemology) from reality itself (ontology); (ii) Intuition vs. Reason, drawing on dual-process theory to separate fast, emotional judgments from slow, reflective thinking; and (iii) Conflict vs. Confirmation, which examines whether ideas are critically tested through disagreement or simply reinforced through mutual validation. Each dimension captures a distinct failure mode, and their combination amplifies misalignment. Rose-Frame does not attempt to fix LLMs with more data or rules. Instead, it offers a reflective tool that makes both the model's limitations and the user's assumptions visible, enabling more transparent and critically aware AI deployment. It reframes alignment as cognitive governance: intuition, whether human or artificial, must remain governed by human reason. Only by embedding reflective, falsifiable oversight can we align machine fluency with human understanding.

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored, particularly in evaluating the quality of their reasoning processes alongside final outputs. Here, we introduce MedR-Bench, a benchmarking dataset of 1,453 structured patient cases, annotated with reasoning references derived from clinical case reports. Spanning 13 body systems and 10 specialties, it includes both common and rare diseases. To comprehensively evaluate LLM performance, we propose a framework encompassing three critical examination recommendation, diagnostic decision-making, and treatment planning, simulating the entire patient care journey. To assess reasoning quality, we present the Reasoning Evaluator, a novel automated system that objectively scores free-text reasoning responses based on efficiency, actuality, and completeness using dynamic cross-referencing and evidence checks. Using this benchmark, we evaluate five state-of-the-art reasoning LLMs, including DeepSeek-R1, OpenAI-o3-mini, and Gemini-2.0-Flash Thinking, etc. Our results show that current LLMs achieve over 85% accuracy in relatively simple diagnostic tasks when provided with sufficient examination results. However, performance declines in more complex tasks, such as examination recommendation and treatment planning. While reasoning outputs are generally reliable, with factuality scores exceeding 90%, critical reasoning steps are frequently missed. These findings underscore both the progress and limitations of clinical LLMs. Notably, open-source models like DeepSeek-R1 are narrowing the gap with proprietary systems, highlighting their potential to drive accessible and equitable advancements in healthcare.

Verification is crucial for effective mathematical reasoning. We present a new temporal consistency method where verifiers iteratively refine their judgments based on the previous assessment. Unlike one-round verification or multi-model debate approaches, our method leverages consistency in a sequence of self-reflection actions to improve verification accuracy. Empirical evaluations across diverse mathematical process error identification benchmarks (Mathcheck, ProcessBench, and PRM800K) show consistent performance improvements over baseline methods. When applied to the recent DeepSeek R1 distilled models, our method demonstrates strong performance, enabling 7B/8B distilled models to outperform all 70B/72B models and GPT-4o on ProcessBench. Notably, the distilled 14B model with our method achieves performance comparable to Deepseek-R1. Our codes are available at https://github.com/jcguo123/Temporal-Consistency

Visual reasoning is central to human cognition, enabling individuals to interpret and abstractly understand their environment. Although recent Multimodal Large Language Models (MLLMs) have demonstrated impressive performance across language and vision-language tasks, existing benchmarks primarily measure recognition-based skills and inadequately assess true visual reasoning capabilities. To bridge this critical gap, we introduce VERIFY, a benchmark explicitly designed to isolate and rigorously evaluate the visual reasoning capabilities of state-of-the-art MLLMs. VERIFY compels models to reason primarily from visual information, providing minimal textual context to reduce reliance on domain-specific knowledge and linguistic biases. Each problem is accompanied by a human-annotated reasoning path, making it the first to provide in-depth evaluation of model decision-making processes. Additionally, we propose novel metrics that assess visual reasoning fidelity beyond mere accuracy, highlighting critical imbalances in current model reasoning patterns. Our comprehensive benchmarking of leading MLLMs uncovers significant limitations, underscoring the need for a balanced and holistic approach to both perception and reasoning. For more teaser and testing, visit our project page (https://verify-eqh.pages.dev/).

Building upon our previous investigations of O1 replication (Part 1: Journey Learning [Qin et al., 2024] and Part 2: Distillation [Huang et al., 2024]), this work explores the potential of inference-time scaling in large language models (LLMs) for medical reasoning tasks, ranging from diagnostic decision-making to treatment planning. Through extensive experiments on medical benchmarks of varying complexity (MedQA, Medbullets, and JAMA Clinical Challenges), our investigation reveals several key insights: (1) Increasing inference time does lead to improved performance. With a modest training set of 500 samples, our model yields substantial performance improvements of 6%-11%. (2) Task complexity directly correlates with the required length of reasoning chains, confirming the necessity of extended thought processes for challenging problems. (3) The differential diagnoses generated by our model adhere to the principles of the hypothetico-deductive method, producing a list of potential conditions that may explain a patient's symptoms and systematically narrowing these possibilities by evaluating the evidence. These findings demonstrate the promising synergy between inference-time scaling and journey learning in advancing LLMs' real-world clinical reasoning capabilities.

While Large Language Models (LLMs) can generate fluent and convincing responses, they are not necessarily correct. This is especially apparent in the popular decompose-then-verify factuality evaluation pipeline, where LLMs evaluate generations by decomposing the generations into individual, valid claims. Factuality evaluation is especially important for medical answers, since incorrect medical information could seriously harm the patient. However, existing factuality systems are a poor match for the medical domain, as they are typically only evaluated on objective, entity-centric, formulaic texts such as biographies and historical topics. This differs from condition-dependent, conversational, hypothetical, sentence-structure diverse, and subjective medical answers, which makes decomposition into valid facts challenging. We propose MedScore, a new pipeline to decompose medical answers into condition-aware valid facts and verify against in-domain corpora. Our method extracts up to three times more valid facts than existing methods, reducing hallucination and vague references, and retaining condition-dependency in facts. The resulting factuality score substantially varies by decomposition method, verification corpus, and used backbone LLM, highlighting the importance of customizing each step for reliable factuality evaluation by using our generalizable and modularized pipeline for domain adaptation.

In this paper, we present and implement a multi-dimensional, modular framework for performing deep argument analysis (DeepA2) using current pre-trained language models (PTLMs). ArgumentAnalyst -- a T5 model (Raffel et al. 2020) set up and trained within DeepA2 -- reconstructs argumentative texts, which advance an informal argumentation, as valid arguments: It inserts, e.g., missing premises and conclusions, formalizes inferences, and coherently links the logical reconstruction to the source text. We create a synthetic corpus for deep argument analysis, and evaluate ArgumentAnalyst on this new dataset as well as on existing data, specifically EntailmentBank (Dalvi et al. 2021). Our empirical findings vindicate the overall framework and highlight the advantages of a modular design, in particular its ability to emulate established heuristics (such as hermeneutic cycles), to explore the model's uncertainty, to cope with the plurality of correct solutions (underdetermination), and to exploit higher-order evidence.

Online medical consultation (OMC) restricts doctors to gathering patient information solely through inquiries, making the already complex sequential decision-making process of diagnosis even more challenging. Recently, the rapid advancement of large language models has demonstrated a significant potential to transform OMC. However, most studies have primarily focused on improving diagnostic accuracy under conditions of relatively sufficient information, while paying limited attention to the "inquiry" phase of the consultation process. This lack of focus has left the relationship between "inquiry" and "diagnosis" insufficiently explored. In this paper, we first extract real patient interaction strategies from authentic doctor-patient conversations and use these strategies to guide the training of a patient simulator that closely mirrors real-world behavior. By inputting medical records into our patient simulator to simulate patient responses, we conduct extensive experiments to explore the relationship between "inquiry" and "diagnosis" in the consultation process. Experimental results demonstrate that inquiry and diagnosis adhere to the Liebig's law: poor inquiry quality limits the effectiveness of diagnosis, regardless of diagnostic capability, and vice versa. Furthermore, the experiments reveal significant differences in the inquiry performance of various models. To investigate this phenomenon, we categorize the inquiry process into four types: (1) chief complaint inquiry; (2) specification of known symptoms; (3) inquiry about accompanying symptoms; and (4) gathering family or medical history. We analyze the distribution of inquiries across the four types for different models to explore the reasons behind their significant performance differences. We plan to open-source the weights and related code of our patient simulator at https://github.com/LIO-H-ZEN/PatientSimulator.

Large Reasoning Models (LRMs) achieve strong performance by generating long reasoning traces with reflection. Through a large-scale empirical analysis, we find that a substantial fraction of reflective steps consist of self-verification (recheck) that repeatedly confirm intermediate results. These rechecks occur frequently across models and benchmarks, yet the vast majority are confirmatory rather than corrective, rarely identifying errors and altering reasoning outcomes. This reveals a mismatch between how often self-verification is activated and how often it is actually useful. Motivated by this, we propose a novel, experience-driven test-time framework that reduces the overused verification. Our method detects the activation of recheck behavior, consults an offline experience pool of past verification outcomes, and estimates whether a recheck is likely unnecessary via efficient retrieval. When historical experience suggests unnecessary, a suppression signal redirects the model to proceed. Across multiple model and benchmarks, our approach reduces token usage up to 20.3% while maintaining the accuracy, and in some datasets even yields accuracy improvements.

We present SciClaimEval, a new scientific dataset for the claim verification task. Unlike existing resources, SciClaimEval features authentic claims, including refuted ones, directly extracted from published papers. To create refuted claims, we introduce a novel approach that modifies the supporting evidence (figures and tables), rather than altering the claims or relying on large language models (LLMs) to fabricate contradictions. The dataset provides cross-modal evidence with diverse representations: figures are available as images, while tables are provided in multiple formats, including images, LaTeX source, HTML, and JSON. SciClaimEval contains 1,664 annotated samples from 180 papers across three domains, machine learning, natural language processing, and medicine, validated through expert annotation. We benchmark 11 multimodal foundation models, both open-source and proprietary, across the dataset. Results show that figure-based verification remains particularly challenging for all models, as a substantial performance gap remains between the best system and human baseline.

Misinformation and disinformation demand fact checking that goes beyond simple evidence-based reasoning. Existing benchmarks fall short: they are largely single modality (text-only), span short time horizons, use shallow evidence, cover domains unevenly, and often omit full articles -- obscuring models' real-world capability. We present MMM-Fact, a large-scale benchmark of 125,449 fact-checked statements (1995--2025) across multiple domains, each paired with the full fact-check article and multimodal evidence (text, images, videos, tables) from four fact-checking sites and one news outlet. To reflect verification effort, each statement is tagged with a retrieval-difficulty tier -- Basic (1--5 sources), Intermediate (6--10), and Advanced (>10) -- supporting fairness-aware evaluation for multi-step, cross-modal reasoning. The dataset adopts a three-class veracity scheme (true/false/not enough information) and enables tasks in veracity prediction, explainable fact-checking, complex evidence aggregation, and longitudinal analysis. Baselines with mainstream LLMs show MMM-Fact is markedly harder than prior resources, with performance degrading as evidence complexity rises. MMM-Fact offers a realistic, scalable benchmark for transparent, reliable, multimodal fact-checking.

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic efficiency and accuracy, deep learning-based methods such as Convolutional Neural Networks and Vision Transformers have been proposed for the automatic classification of brain MRIs. However, despite their strong predictive performance, these models find limited clinical utility due to their opaque decision making. In this work, we propose a framework that integrates two core components to enhance diagnostic transparency. First, we introduce a modular pipeline for converting 3D T1-weighted brain MRIs into textual radiology reports. Second, we explore the potential of modern Large Language Models (LLMs) to assist clinicians in the differential diagnosis between Frontotemporal dementia subtypes, Alzheimer's disease, and normal aging based on the generated reports. To bridge the gap between predictive accuracy and explainability, we employ reinforcement learning to incentivize diagnostic reasoning in LLMs. Without requiring supervised reasoning traces or distillation from larger models, our approach enables the emergence of structured diagnostic rationales grounded in neuroimaging findings. Unlike post-hoc explainability methods that retrospectively justify model decisions, our framework generates diagnostic rationales as part of the inference process-producing causally grounded explanations that inform and guide the model's decision-making process. In doing so, our framework matches the diagnostic performance of existing deep learning methods while offering rationales that support its diagnostic conclusions.

Hallucination plagues even frontier LLMs--but how bad is it really for summarizing academic papers? We evaluate Factored Verification, a simple automated method for detecting hallucinations in abstractive summaries. This method sets a new SotA on hallucination detection in the summarization task of the HaluEval benchmark, achieving 76.2% accuracy. We then use this method to estimate how often language models hallucinate when summarizing across multiple academic papers and find 0.62 hallucinations in the average ChatGPT (16k) summary, 0.84 for GPT-4, and 1.55 for Claude 2. We ask models to self-correct using Factored Critiques and find that this lowers the number of hallucinations to 0.49 for ChatGPT, 0.46 for GPT-4, and 0.95 for Claude 2. The hallucinations we find are often subtle, so we advise caution when using models to synthesize academic papers.

The pervasiveness of large language models and generative AI in online media has amplified the need for effective automated fact-checking to assist fact-checkers in tackling the increasing volume and sophistication of misinformation. The complex nature of fact-checking demands that automated fact-checking systems provide explanations that enable fact-checkers to scrutinise their outputs. However, it is unclear how these explanations should align with the decision-making and reasoning processes of fact-checkers to be effectively integrated into their workflows. Through semi-structured interviews with fact-checking professionals, we bridge this gap by: (i) providing an account of how fact-checkers assess evidence, make decisions, and explain their processes; (ii) examining how fact-checkers use automated tools in practice; and (iii) identifying fact-checker explanation requirements for automated fact-checking tools. The findings show unmet explanation needs and identify important criteria for replicable fact-checking explanations that trace the model's reasoning path, reference specific evidence, and highlight uncertainty and information gaps.

Generation of plausible yet incorrect factual information, termed hallucination, is an unsolved issue in large language models. We study the ability of language models to deliberate on the responses they give in order to correct their mistakes. We develop the Chain-of-Verification (CoVe) method whereby the model first (i) drafts an initial response; then (ii) plans verification questions to fact-check its draft; (iii) answers those questions independently so the answers are not biased by other responses; and (iv) generates its final verified response. In experiments, we show CoVe decreases hallucinations across a variety of tasks, from list-based questions from Wikidata, closed book MultiSpanQA and longform text generation.

Recent advances in large language models have enabled deep research systems that generate expert-level reports through multi-step reasoning and evidence-based synthesis. However, evaluating such reports remains challenging: report quality is multifaceted, making it difficult to determine what to assess and by what criteria; LLM-based judges may miss errors that require domain expertise to identify; and because deep research relies on retrieved evidence, report-wide claim verification is also necessary. To address these issues, we propose DEER, a benchmark for evaluating expert-level deep research reports. DEER systematizes evaluation criteria with an expert-developed taxonomy (7 dimensions, 25 subdimensions) operationalized as 101 fine-grained rubric items. We also provide task-specific Expert Evaluation Guidance to support LLM-based judging. Alongside rubric-based assessment, we propose a claim verification architecture that verifies both cited and uncited claims and quantifies evidence quality. Experiments show that while current deep research systems can produce structurally plausible reports that cite external evidence, there is room for improvement in fulfilling expert-level user requests and achieving logical completeness. Beyond simple performance comparisons, DEER makes system strengths and limitations interpretable and provides diagnostic signals for improvement.

Large Language Models have demonstrated remarkable capabilities across diverse tasks, yet they frequently generate hallucinations outputs that are fluent but factually incorrect or unsupported. We propose Counterfactual Probing, a novel approach for detecting and mitigating hallucinations in LLM outputs. Our method dynamically generates counterfactual statements that appear plausible but contain subtle factual errors, then evaluates the model's sensitivity to these perturbations. We hypothesize that genuine knowledge exhibits robustness to counterfactual variations, while hallucinated content shows inconsistent confidence patterns when confronted with plausible alternatives. Our comprehensive evaluation on TruthfulQA, factual statement datasets, and curated hallucination examples demonstrates that counterfactual probing achieves superior detection performance compared to baseline methods, while our adaptive mitigation strategies reduce hallucination scores by an average of 24.5%. The approach requires no model retraining and can be integrated into existing LLM pipelines as a realtime verification mechanism.

Multimodal Large Language Models (MLLMs) have achieved impressive performances in mathematical reasoning, yet they remain vulnerable to visual hallucinations and logical inconsistencies that standard outcome-based supervision fails to mitigate. While Process Reward Models (PRMs) promise step-by-step verification, current approaches typically operate as scalar scorers or generative critics that suffer from sycophancy, blindly validating the flawed hypotheses rather than grounding them in visual reality. To bridge this gap, we introduce TIM-PRM (Tool-Integrated Multimodal PRM), a novel agentic framework that transforms verification from a passive classification task into an active, tool-augmented investigation. TIM-PRM is trained to explicitly plan verification strategies and utilizes a mechanism of Independent Question Asking to query evidence via external tools, effectively decoupling verification from the reasoning context to eliminate confirmation bias. We instantiate this method by curating a high-quality dataset of tool-integrated verification trajectories. Extensive experiments on VisualProcessBench demonstrate that our 8B parameter model surpasses existing open-source multimodal PRMs, significantly outperforming much larger models like Qwen2.5-72B and InternVL-78B, while offering interpretable insights into the verification process.

The advancement of Large Language Models (LLMs) has greatly improved our ability to process complex language. However, accurately detecting logical fallacies remains a significant challenge. This study presents a novel and effective prompt formulation approach for logical fallacy detection, applicable in both supervised (fine-tuned) and unsupervised (zero-shot) settings. Our method enriches input text incorporating implicit contextual information -- counterarguments, explanations, and goals -- which we query for validity within the context of the argument. We then rank these queries based on confidence scores to inform classification. We evaluate our approach across multiple datasets from 5 domains, covering 29 distinct fallacy types, using models from the GPT and LLaMA series. The results show substantial improvements over state-of-the-art models, with F1 score increases of up to 0.60 in zero-shot settings and up to 0.45 in fine-tuned models. Extensive analyses further illustrate why and how our method excels.

In this paper, we present the current progress of the project Verif.ai, an open-source scientific generative question-answering system with referenced and verified answers. The components of the system are (1) an information retrieval system combining semantic and lexical search techniques over scientific papers (PubMed), (2) a fine-tuned generative model (Mistral 7B) taking top answers and generating answers with references to the papers from which the claim was derived, and (3) a verification engine that cross-checks the generated claim and the abstract or paper from which the claim was derived, verifying whether there may have been any hallucinations in generating the claim. We are reinforcing the generative model by providing the abstract in context, but in addition, an independent set of methods and models are verifying the answer and checking for hallucinations. Therefore, we believe that by using our method, we can make scientists more productive, while building trust in the use of generative language models in scientific environments, where hallucinations and misinformation cannot be tolerated.

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that report single or coarse-grained metrics are lack the granularity required for specialized clinical support and fail to assess the reliability of reasoning mechanisms. To address this, we propose a paradigm shift toward multidimensional, fine-grained and in-depth evaluation. Based on a two-stage systematic construction pipeline designed for this paradigm, we instantiate it with MedRCube. We benchmark 33 MLLMs, Lingshu-32B achieve top-tier performance. Crucially, MedRCube exposes a series of pronounced insights inaccessible under prior evaluation settings. Furthermore, we introduce a credibility evaluation subset to quantify reasoning credibility, uncover a highly significant positive association between shortcut behavior and diagnostic task performance, raising concerns for clinically trustworthy deployment. The resources of this work can be found at https://github.com/F1mc/MedRCube.

This paper investigates the rational thinking capability of Large Language Models (LLMs) in multi-round argumentative debates by exploring the impact of fallacious arguments on their logical reasoning performance. More specifically, we present Logic Competence Measurement Benchmark (LOGICOM), a diagnostic benchmark to assess the robustness of LLMs against logical fallacies. LOGICOM involves two agents: a persuader and a debater engaging in a multi-round debate on a controversial topic, where the persuader tries to convince the debater of the correctness of its claim. First, LOGICOM assesses the potential of LLMs to change their opinions through reasoning. Then, it evaluates the debater's performance in logical reasoning by contrasting the scenario where the persuader employs logical fallacies against one where logical reasoning is used. We use this benchmark to evaluate the performance of GPT-3.5 and GPT-4 using a dataset containing controversial topics, claims, and reasons supporting them. Our findings indicate that both GPT-3.5 and GPT-4 can adjust their opinion through reasoning. However, when presented with logical fallacies, GPT-3.5 and GPT-4 are erroneously convinced 41% and 69% more often, respectively, compared to when logical reasoning is used. Finally, we introduce a new dataset containing over 5k pairs of logical vs. fallacious arguments. The source code and dataset of this work are made publicly available.

Large language models (LLMs) have recently showcased remarkable capabilities, spanning a wide range of tasks and applications, including those in the medical domain. Models like GPT-4 excel in medical question answering but may face challenges in the lack of interpretability when handling complex tasks in real clinical settings. We thus introduce the diagnostic reasoning dataset for clinical notes (DiReCT), aiming at evaluating the reasoning ability and interpretability of LLMs compared to human doctors. It contains 511 clinical notes, each meticulously annotated by physicians, detailing the diagnostic reasoning process from observations in a clinical note to the final diagnosis. Additionally, a diagnostic knowledge graph is provided to offer essential knowledge for reasoning, which may not be covered in the training data of existing LLMs. Evaluations of leading LLMs on DiReCT bring out a significant gap between their reasoning ability and that of human doctors, highlighting the critical need for models that can reason effectively in real-world clinical scenarios.

The rapid propagation of misinformation poses substantial risks to public interest. To combat misinformation, large language models (LLMs) are adapted to automatically verify claim credibility. Nevertheless, existing methods heavily rely on the embedded knowledge within LLMs and / or black-box APIs for evidence collection, leading to subpar performance with smaller LLMs or upon unreliable context. In this paper, we propose retrieval augmented fact verification through the synthesis of contrasting arguments (RAFTS). Upon input claims, RAFTS starts with evidence retrieval, where we design a retrieval pipeline to collect and re-rank relevant documents from verifiable sources. Then, RAFTS forms contrastive arguments (i.e., supporting or refuting) conditioned on the retrieved evidence. In addition, RAFTS leverages an embedding model to identify informative demonstrations, followed by in-context prompting to generate the prediction and explanation. Our method effectively retrieves relevant documents as evidence and evaluates arguments from varying perspectives, incorporating nuanced information for fine-grained decision-making. Combined with informative in-context examples as prior, RAFTS achieves significant improvements to supervised and LLM baselines without complex prompts. We demonstrate the effectiveness of our method through extensive experiments, where RAFTS can outperform GPT-based methods with a significantly smaller 7B LLM.

Retrieval-enhanced methods have become a primary approach in fact verification (FV); it requires reasoning over multiple retrieved pieces of evidence to verify the integrity of a claim. To retrieve evidence, existing work often employs off-the-shelf retrieval models whose design is based on the probability ranking principle. We argue that, rather than relevance, for FV we need to focus on the utility that a claim verifier derives from the retrieved evidence. We introduce the feedback-based evidence retriever(FER) that optimizes the evidence retrieval process by incorporating feedback from the claim verifier. As a feedback signal we use the divergence in utility between how effectively the verifier utilizes the retrieved evidence and the ground-truth evidence to produce the final claim label. Empirical studies demonstrate the superiority of FER over prevailing baselines.

Conversational diagnosis prediction requires models to track evolving evidence in streaming clinical conversations and decide when to commit to a diagnosis. Existing medical dialogue corpora are largely dyadic or lack the multi-party workflow and annotations needed for this setting. We introduce an ePCR-grounded, topic-flow-based multi-agent generation pipeline that iteratively plans, generates, and self-refines dialogues with rule-based factual and topic flow checks. The pipeline yields EMSDialog, a dataset of 4,414 synthetic multi-speaker EMS conversations based on a real-world ePCR dataset, annotated with 43 diagnoses, speaker roles, and turn-level topics. Human and LLM evaluations confirm high quality and realism of EMSDialog using both utterance- and conversation-level metrics. Results show that EMSDialog-augmented training improves accuracy, timeliness, and stability of EMS conversational diagnosis prediction. Our datasets and code are publicly available at https://uva-dsa.github.io/EMSDialog

We conduct a systematic audit of three widely used reasoning benchmarks, SocialIQa, FauxPas-EAI, and ToMi, and uncover pervasive flaws in both benchmark items and evaluation methodology. Using five LLMs (GPT-{3, 3.5, 4, o1}, and LLaMA 3.1) as diagnostic tools, we identify structural, semantic, and pragmatic issues in benchmark design (e.g., duplicated items, ambiguous wording, and implausible answers), as well as scoring procedures that prioritize output form over reasoning process. Through systematic human annotation and re-evaluation on cleaned benchmark subsets, we find that model scores often improve not due to due to erratic surface wording variations and not to improved reasoning. Infact, further analyses show that model performance is highly sensitive to minor input variations such as context availability and phrasing, revealing that high scores may reflect alignment with format-specific cues rather than consistent inference based on the input. These findings challenge the validity of current benchmark-based claims about reasoning in LLMs, and highlight the need for evaluation protocols that assess reasoning as a process of drawing inference from available information, rather than as static output selection. We release audited data and evaluation tools to support more interpretable and diagnostic assessments of model reasoning.

Artificial intelligence has advanced in Medical Visual Question Answering (Med-VQA), but prevalent research tends to focus on the accuracy of the answers, often overlooking the reasoning paths and interpretability, which are crucial in clinical settings. Besides, current Med-VQA algorithms, typically reliant on singular models, lack the robustness needed for real-world medical diagnostics which usually require collaborative expert evaluation. To address these shortcomings, this paper presents MedCoT, a novel hierarchical expert verification reasoning chain method designed to enhance interpretability and accuracy in biomedical imaging inquiries. MedCoT is predicated on two principles: The necessity for explicit reasoning paths in Med-VQA and the requirement for multi-expert review to formulate accurate conclusions. The methodology involves an Initial Specialist proposing diagnostic rationales, followed by a Follow-up Specialist who validates these rationales, and finally, a consensus is reached through a vote among a sparse Mixture of Experts within the locally deployed Diagnostic Specialist, which then provides the definitive diagnosis. Experimental evaluations on four standard Med-VQA datasets demonstrate that MedCoT surpasses existing state-of-the-art approaches, providing significant improvements in performance and interpretability.

We contribute the largest publicly available dataset of naturally occurring factual claims for the purpose of automatic claim verification. It is collected from 26 fact checking websites in English, paired with textual sources and rich metadata, and labelled for veracity by human expert journalists. We present an in-depth analysis of the dataset, highlighting characteristics and challenges. Further, we present results for automatic veracity prediction, both with established baselines and with a novel method for joint ranking of evidence pages and predicting veracity that outperforms all baselines. Significant performance increases are achieved by encoding evidence, and by modelling metadata. Our best-performing model achieves a Macro F1 of 49.2%, showing that this is a challenging testbed for claim veracity prediction.

Users increasingly rely on Large Language Models (LLMs) for Deep Research, using them to synthesize diverse sources into structured reports that support understanding and action. In this context, the practical reliability of such reports hinges on logical quality: whether the report's claims and arguments are explicitly supported and can be trusted as a basis for downstream use, rather than merely appearing fluent or informative. However, current evaluation frameworks largely overlook this requirement. To bridge this gap, we introduce ReportLogic, a benchmark that quantifies report-level logical quality through a reader-centric lens of auditability. Specifically, ReportLogic adopts a hierarchical taxonomy that evaluates whether readers can (1) trace an on-topic report structure with a unified analytical arc (Macro-Logic), (2) understand the progression with necessary context (Expositional-Logic), and (3) verify conclusions via explicit claim--support (Structural-Logic). Based on this taxonomy, we construct a human-annotated rubric-guided dataset and train an open-source LogicJudge for scalable evaluation. We further evaluate judge robustness via adversarial attacks, showing that off-the-shelf LLM judges are frequently influenced by superficial cues (e.g., verbosity), and reasoning modes can mask broken support relations. Overall, our results provide actionable guidance for building more robust logic evaluators and improving the logical reliability of LLM-generated reports.

Large language models demonstrate remarkable reasoning capabilities but often produce unreliable or incorrect responses. Existing verification methods are typically model-specific or domain-restricted, requiring significant computational resources and lacking scalability across diverse reasoning tasks. To address these limitations, we propose VerifiAgent, a unified verification agent that integrates two levels of verification: meta-verification, which assesses completeness and consistency in model responses, and tool-based adaptive verification, where VerifiAgent autonomously selects appropriate verification tools based on the reasoning type, including mathematical, logical, or commonsense reasoning. This adaptive approach ensures both efficiency and robustness across different verification scenarios. Experimental results show that VerifiAgent outperforms baseline verification methods (e.g., deductive verifier, backward verifier) among all reasoning tasks. Additionally, it can further enhance reasoning accuracy by leveraging feedback from verification results. VerifiAgent can also be effectively applied to inference scaling, achieving better results with fewer generated samples and costs compared to existing process reward models in the mathematical reasoning domain. Code is available at https://github.com/Jiuzhouh/VerifiAgent

Developing reliable AI systems to assist human clinicians in multi-modal medical diagnosis has long been a key objective for researchers. Recently, Multi-modal Large Language Models (MLLMs) have gained significant attention and achieved success across various domains. With strong reasoning capabilities and the ability to perform diverse tasks based on user instructions, they hold great potential for enhancing medical diagnosis. However, directly applying MLLMs to the medical domain still presents challenges. They lack detailed perception of visual inputs, limiting their ability to perform quantitative image analysis, which is crucial for medical diagnostics. Additionally, MLLMs often exhibit hallucinations and inconsistencies in reasoning, whereas clinical diagnoses must adhere strictly to established criteria. To address these challenges, we propose MedAgent-Pro, an evidence-based reasoning agentic system designed to achieve reliable, explainable, and precise medical diagnoses. This is accomplished through a hierarchical workflow: at the task level, knowledge-based reasoning generate reliable diagnostic plans for specific diseases following retrieved clinical criteria. While at the case level, multiple tool agents process multi-modal inputs, analyze different indicators according to the plan, and provide a final diagnosis based on both quantitative and qualitative evidence. Comprehensive experiments on both 2D and 3D medical diagnosis tasks demonstrate the superiority and effectiveness of MedAgent-Pro, while case studies further highlight its reliability and interpretability. The code is available at https://github.com/jinlab-imvr/MedAgent-Pro.

Knowledge graphs (KGs) are increasingly used to support large lan guage model (LLM) reasoning, but standard triplet-based KGs treat each relation as globally valid. In many settings, whether a relation should count as evidence depends on the context. We therefore formulate triplet validity as a triplet-specific function of context and refer to this formulation as a Quantum Knowledge Graph (QKG). We instantiate QKG in medicine using a diabetes-centered PrimeKG subgraph, whose 68,651 context-sensitive relations are further annotated with patient-group-specific constraints. We evaluate it in a reasoner--validator pipeline for medical question answering on a KG-grounded subset of MedReason containing 2,788 questions. With Haiku-4.5 as both the Reasoner and the Validator, KG-backed validation significantly improves over a no-validator baseline (+0.61 pp), and QKG with context matching yields the largest gain, outperforming both KG validation without context matching (+0.79 pp) and the no-validator baseline (+1.40 pp; paired McNemar, all p<0.05). Under a stronger validator (Qwen-3.6-Plus), the raw QKG gain over the no-validator baseline grows from +1.40 pp to +5.96 pp; the context-matching gap is non-significant (p=0.73) on the raw set but becomes borderline significant (p=0.05) after adjustment for knowledge leakage and suspicious questions, consistent with a benchmark-gold ceiling rather than a QKG limitation. Taken together, the results support the view that the value of a KG in LLM-based clinical reasoning lies not merely in storing medically related facts, but in representing whether those facts are applicable to the specific patient context. For reproducibility and further research, we release the curated QKG datasets and source code.https://github.com/HKAI-Sci/QKG

Large Reasoning Models (LRMs) extend large language models with explicit, multi-step reasoning traces to enhance transparency and performance on complex tasks. However, these reasoning traces can be redundant or logically inconsistent, making them a new source of hallucination that is difficult to detect. Existing hallucination detection methods focus primarily on answer-level uncertainty and often fail to detect hallucinations or logical inconsistencies arising from the model's reasoning trace. This oversight is particularly problematic for LRMs, where the explicit thinking trace is not only an important support to the model's decision-making process but also a key source of potential hallucination. To this end, we propose RACE (Reasoning and Answer Consistency Evaluation), a novel framework specifically tailored for hallucination detection in LRMs. RACE operates by extracting essential reasoning steps and computing four diagnostic signals: inter-sample consistency of reasoning traces, entropy-based answer uncertainty, semantic alignment between reasoning and answers, and internal coherence of reasoning. This joint analysis enables fine-grained hallucination detection even when the final answer appears correct. Experiments across datasets and different LLMs demonstrate that RACE outperforms existing hallucination detection baselines, offering a robust and generalizable solution for evaluating LRMs. Our code is available at: https://github.com/bebr2/RACE.

Psychological defenses are strategies, often automatic, that people use to manage distress. Rigid or overuse of defenses is negatively linked to mental health and shapes what speakers disclose and how they accept or resist help. However, defenses are complex and difficult to reliably measure, particularly in clinical dialogues. We introduce PsyDefConv, a dialogue corpus with help seeker utterances labeled for defense level, and DMRS Co-Pilot, a four-stage pipeline that provides evidence-based pre-annotations. The corpus contains 200 dialogues and 4709 utterances, including 2336 help seeker turns, with labeling and Cohen's kappa 0.639. In a counterbalanced study, the co-pilot reduced average annotation time by 22.4%. In expert review, it averaged 4.62 for evidence, 4.44 for clinical plausibility, and 4.40 for insight on a seven-point scale. Benchmarks with strong language models in zero-shot and fine-tuning settings demonstrate clear headroom, with the best macro F1-score around 30% and a tendency to overpredict mature defenses. Corpus analyses confirm that mature defenses are most common and reveal emotion-specific deviations. We will release the corpus, annotations, code, and prompts to support research on defensive functioning in language.

Tool-augmented large language models (LLMs) are rapidly being integrated into real-world applications. Due to the lack of benchmarks, the community still needs to fully understand the hallucination issues within these models. To address this challenge, we introduce a comprehensive diagnostic benchmark, ToolBH. Specifically, we assess the LLM's hallucinations through two perspectives: depth and breadth. In terms of depth, we propose a multi-level diagnostic process, including (1) solvability detection, (2) solution planning, and (3) missing-tool analysis. For breadth, we consider three scenarios based on the characteristics of the toolset: missing necessary tools, potential tools, and limited functionality tools. Furthermore, we developed seven tasks and collected 700 evaluation samples through multiple rounds of manual annotation. The results show the significant challenges presented by the ToolBH benchmark. The current advanced models Gemini-1.5-Pro and GPT-4o only achieve a total score of 45.3 and 37.0, respectively, on a scale of 100. In this benchmark, larger model parameters do not guarantee better performance; the training data and response strategies also play a crucial role in tool-enhanced LLM scenarios. Our diagnostic analysis indicates that the primary reason for model errors lies in assessing task solvability. Additionally, open-weight models suffer from performance drops with verbose replies, whereas proprietary models excel with longer reasoning.

Large language models (LLMs) remain unreliable for high-stakes claim verification due to hallucinations and shallow reasoning. While retrieval-augmented generation (RAG) and multi-agent debate (MAD) address this, they are limited by one-pass retrieval and unstructured debate dynamics. We propose a courtroom-style multi-agent framework, PROClaim, that reformulates verification as a structured, adversarial deliberation. Our approach integrates specialized roles (e.g., Plaintiff, Defense, Judge) with Progressive RAG (P-RAG) to dynamically expand and refine the evidence pool during the debate. Furthermore, we employ evidence negotiation, self-reflection, and heterogeneous multi-judge aggregation to enforce calibration, robustness, and diversity. In zero-shot evaluations on the Check-COVID benchmark, PROClaim achieves 81.7% accuracy, outperforming standard multi-agent debate by 10.0 percentage points, with P-RAG driving the primary performance gains (+7.5 pp). We ultimately demonstrate that structural deliberation and model heterogeneity effectively mitigate systematic biases, providing a robust foundation for reliable claim verification. Our code and data are publicly available at https://github.com/mnc13/PROClaim.

Vietnamese medical research has become an increasingly vital domain, particularly with the rise of intelligent technologies aimed at reducing time and resource burdens in clinical diagnosis. Recent advances in vision-language models (VLMs), such as Gemini and GPT-4V, have sparked a growing interest in applying AI to healthcare. However, most existing VLMs lack exposure to Vietnamese medical data, limiting their ability to generate accurate and contextually appropriate diagnostic outputs for Vietnamese patients. To address this challenge, we introduce ViX-Ray, a novel dataset comprising 5,400 Vietnamese chest X-ray images annotated with expert-written findings and impressions from physicians at a major Vietnamese hospital. We analyze linguistic patterns within the dataset, including the frequency of mentioned body parts and diagnoses, to identify domain-specific linguistic characteristics of Vietnamese radiology reports. Furthermore, we fine-tune five state-of-the-art open-source VLMs on ViX-Ray and compare their performance to leading proprietary models, GPT-4V and Gemini. Our results show that while several models generate outputs partially aligned with clinical ground truths, they often suffer from low precision and excessive hallucination, especially in impression generation. These findings not only demonstrate the complexity and challenge of our dataset but also establish ViX-Ray as a valuable benchmark for evaluating and advancing vision-language models in the Vietnamese clinical domain.

Podcasts are a popular medium on the web, featuring diverse and multilingual content that often includes unverified claims. Fact-checking podcasts is a challenging task, requiring transcription, annotation, and claim verification, all while preserving the contextual details of spoken content. Our tool offers a novel approach to tackle these challenges by enabling real-time annotation of podcasts during playback. This unique capability allows users to listen to the podcast and annotate key elements, such as check-worthy claims, claim spans, and contextual errors, simultaneously. By integrating advanced transcription models like OpenAI's Whisper and leveraging crowdsourced annotations, we create high-quality datasets to fine-tune multilingual transformer models such as XLM-RoBERTa for tasks like claim detection and stance classification. Furthermore, we release the annotated podcast transcripts and sample annotations with preliminary experiments.

An important skill in critical thinking and argumentation is the ability to spot and recognize fallacies. Fallacious arguments, omnipresent in argumentative discourse, can be deceptive, manipulative, or simply leading to `wrong moves' in a discussion. Despite their importance, argumentation scholars and NLP researchers with focus on argumentation quality have not yet investigated fallacies empirically. The nonexistence of resources dealing with fallacious argumentation calls for scalable approaches to data acquisition and annotation, for which the serious games methodology offers an appealing, yet unexplored, alternative. We present Argotario, a serious game that deals with fallacies in everyday argumentation. Argotario is a multilingual, open-source, platform-independent application with strong educational aspects, accessible at www.argotario.net.

Large language models have shown promise in clinical decision making, but current approaches struggle to localize and correct errors at specific steps of the reasoning process. This limitation is critical in medicine, where identifying and addressing reasoning errors is essential for accurate diagnosis and effective patient care. We introduce Med-PRM, a process reward modeling framework that leverages retrieval-augmented generation to verify each reasoning step against established medical knowledge bases. By verifying intermediate reasoning steps with evidence retrieved from clinical guidelines and literature, our model can precisely assess the reasoning quality in a fine-grained manner. Evaluations on five medical QA benchmarks and two open-ended diagnostic tasks demonstrate that Med-PRM achieves state-of-the-art performance, with improving the performance of base models by up to 13.50% using Med-PRM. Moreover, we demonstrate the generality of Med-PRM by integrating it in a plug-and-play fashion with strong policy models such as Meerkat, achieving over 80\% accuracy on MedQA for the first time using small-scale models of 8 billion parameters. Our code and data are available at: https://med-prm.github.io/

As AI capabilities increasingly surpass human proficiency in complex tasks, current alignment techniques including SFT and RLHF face fundamental challenges in ensuring reliable oversight. These methods rely on direct human assessment and become untenable when AI outputs exceed human cognitive thresholds. In response to this challenge, we explore two hypotheses: (1) critique of critique can be easier than critique itself, extending the widely-accepted observation that verification is easier than generation to the critique domain, as critique itself is a specialized form of generation; (2) this difficulty relationship is recursively held, suggesting that when direct evaluation is infeasible, performing high-order critiques (e.g., critique of critique of critique) offers a more tractable supervision pathway. To examine these hypotheses, we perform Human-Human, Human-AI, and AI-AI experiments across multiple tasks. Our results demonstrate encouraging evidence supporting these hypotheses and suggest that recursive self-critiquing is a promising direction for scalable oversight.

Background Major depressive disorder (MDD) is a leading cause of global disability, yet current diagnostic approaches often rely on subjective assessments and lack the ability to integrate multimodal clinical information. Large language models (LLMs) hold promise for enhancing diagnostic accuracy through advanced reasoning but face challenges in interpretability, hallucination, and reliance on synthetic data. Methods We developed MDD-Thinker, an LLM-based diagnostic framework that integrates supervised fine-tuning (SFT) with reinforcement learning (RL) to strengthen reasoning ability and interpretability. Using the UK Biobank dataset, we generated 40,000 reasoning samples, supplemented with 10,000 samples from publicly available mental health datasets. The model was fine-tuned on these reasoning corpora, and its diagnostic and reasoning performance was evaluated against machine learning, deep learning, and state-of-the-art LLM baselines. Findings MDD-Thinker achieved an accuracy of 0.8268 and F1-score of 0.8081, significantly outperforming traditional baselines such as SVM and MLP, as well as general-purpose LLMs. Incorporating both SFT and RL yielded the greatest improvements, with relative gains of 29.0% in accuracy, 38.1% in F1-score, and 34.8% in AUC. Moreover, the model demonstrated comparable reasoning performance compared to much larger LLMs, while maintaining computational efficiency. Interpretation This study presents the first reasoning-enhanced LLM framework for MDD diagnosis trained on large-scale real-world clinical data. By integrating SFT and RL, MDD-Thinker balances accuracy, interpretability, and efficiency, offering a scalable approach for intelligent psychiatric diagnostics. These findings suggest that reasoning-oriented LLMs can provide clinically reliable support for MDD detection and may inform broader applications in mental health care.

Large Language Models (LLMs) are often described as being instances of foundation models - that is, models that transfer strongly across various tasks and conditions in few-show or zero-shot manner, while exhibiting scaling laws that predict function improvement when increasing the pre-training scale. These claims of excelling in different functions and tasks rely on measurements taken across various sets of standardized benchmarks showing high scores for such models. We demonstrate here a dramatic breakdown of function and reasoning capabilities of state-of-the-art models trained at the largest available scales which claim strong function, using a simple, short, conventional common sense problem formulated in concise natural language, easily solvable by humans. The breakdown is dramatic, as models also express strong overconfidence in their wrong solutions, while providing often non-sensical "reasoning"-like explanations akin to confabulations to justify and backup the validity of their clearly failed responses, making them sound plausible. Various standard interventions in an attempt to get the right solution, like various type of enhanced prompting, or urging the models to reconsider the wrong solutions again by multi step re-evaluation, fail. We take these initial observations to the scientific and technological community to stimulate urgent re-assessment of the claimed capabilities of current generation of LLMs, Such re-assessment also requires common action to create standardized benchmarks that would allow proper detection of such basic reasoning deficits that obviously manage to remain undiscovered by current state-of-the-art evaluation procedures and benchmarks. Code for reproducing experiments in the paper and raw experiments data can be found at https://github.com/LAION-AI/AIW

Recognizing if LLM output can be grounded in evidence is central to many tasks in NLP: retrieval-augmented generation, summarization, document-grounded dialogue, and more. Current approaches to this kind of "fact-checking" are based on verifying each piece of a model generation against potential evidence using an LLM. However, this process can be very computationally expensive, requiring many calls to LLMs to check a single response. In this work, we show how to build small models that have GPT-4-level performance but for 400x lower cost. We do this by constructing synthetic training data with GPT-4, which involves creating realistic yet challenging instances of factual errors via a structured generation procedure. Training on this data teaches models to check each fact in the claim and recognize synthesis of information across sentences. For evaluation, we unify pre-existing datasets into a benchmark LLM-AggreFact, collected from recent work on fact-checking and grounding LLM generations. Our best system MiniCheck-FT5 (770M parameters) outperforms all systems of comparable size and reaches GPT-4 accuracy. We release LLM-AggreFact, code for data synthesis, and models.

In the midst of widespread misinformation and disinformation through social media and the proliferation of AI-generated texts, it has become increasingly difficult for people to validate and trust information they encounter. Many fact-checking approaches and tools have been developed, but they often lack appropriate explainability or granularity to be useful in various contexts. A text validation method that is easy to use, accessible, and can perform fine-grained evidence attribution has become crucial. More importantly, building user trust in such a method requires presenting the rationale behind each prediction, as research shows this significantly influences people's belief in automated systems. It is also paramount to localize and bring users' attention to the specific problematic content, instead of providing simple blanket labels. In this paper, we present ClaimVer, a human-centric framework tailored to meet users' informational and verification needs by generating rich annotations and thereby reducing cognitive load. Designed to deliver comprehensive evaluations of texts, it highlights each claim, verifies it against a trusted knowledge graph (KG), presents the evidence, and provides succinct, clear explanations for each claim prediction. Finally, our framework introduces an attribution score, enhancing applicability across a wide range of downstream tasks.

Despite substantial progress in fact-verification benchmarks, claims grounded in large-scale structured data remain underexplored. In this work, we introduce ClaimDB, the first fact-verification benchmark where the evidence for claims is derived from compositions of millions of records and multiple tables. ClaimDB consists of 80 unique real-life databases covering a wide range of domains, from governance and healthcare to media, education and the natural sciences. At this scale, verification approaches that rely on "reading" the evidence break down, forcing a timely shift toward reasoning in executable programs. We conduct extensive experiments with 30 state-of-the-art proprietary and open-source (below 70B) LLMs and find that none exceed 83% accuracy, with more than half below 55%. Our analysis also reveals that both closed- and open-source models struggle with abstention -- the ability to admit that there is no evidence to decide -- raising doubts about their reliability in high-stakes data analysis. We release the benchmark, code, and the LLM leaderboard at https://claimdb.github.io .

Recent large language models often answer factual questions correctly. But users can't trust any given claim a model makes without fact-checking, because language models can hallucinate convincing nonsense. In this work we use reinforcement learning from human preferences (RLHP) to train "open-book" QA models that generate answers whilst also citing specific evidence for their claims, which aids in the appraisal of correctness. Supporting evidence is drawn from multiple documents found via a search engine, or from a single user-provided document. Our 280 billion parameter model, GopherCite, is able to produce answers with high quality supporting evidence and abstain from answering when unsure. We measure the performance of GopherCite by conducting human evaluation of answers to questions in a subset of the NaturalQuestions and ELI5 datasets. The model's response is found to be high-quality 80\% of the time on this Natural Questions subset, and 67\% of the time on the ELI5 subset. Abstaining from the third of questions for which it is most unsure improves performance to 90\% and 80\% respectively, approaching human baselines. However, analysis on the adversarial TruthfulQA dataset shows why citation is only one part of an overall strategy for safety and trustworthiness: not all claims supported by evidence are true.

Large reasoning models (e.g., R1, o3) have demonstrated remarkable mathematical problem-solving abilities. However, the high reported accuracy of these advanced models on popular datasets, reliance on purely numerical evaluation and potential benchmark leakage, often masks their true reasoning shortcomings. To address this, we propose leveraging the inherent rigor and methodological complexity of mathematical proofs as a diagnostic tool to expose these hidden failures. Specifically, we introduce the RFMDataset (Reveal Failure Modes), a collection of 200 diverse mathematical proof problems, and thoroughly evaluate advanced models' performance on it. Our in-depth analysis of their failures uncovers 10 fine-grained error types, which shows fundamental limitations in current large reasoning models: 1) large reasoning models grapple profoundly with mathematical proofs, with some generating entirely correct proofs for less than 20% of problems and failing even on basic ones; 2) models exhibit a diverse spectrum of reasoning failures, prominently demonstrating the lack of guarantees for the correctness and rigor of single-step reasoning; and 3) models show hallucination and incompleteness during the reasoning process. Our findings reveal that models' self-reflection is insufficient to resolve the current logical dilemmas, necessitating formalized and fine-grained logical training.

LLMs for clinical decision support often fail under small but clinically meaningful input shifts such as masking a symptom or negating a finding, despite high performance on static benchmarks. These reasoning failures frequently go undetected by standard NLP metrics, which are insensitive to latent representation shifts that drive diagnosis instability. We propose a geometry-aware evaluation framework, LAPD (Latent Agentic Perturbation Diagnostics), which systematically probes the latent robustness of clinical LLMs under structured adversarial edits. Within this framework, we introduce Latent Diagnosis Flip Rate (LDFR), a model-agnostic diagnostic signal that captures representational instability when embeddings cross decision boundaries in PCA-reduced latent space. Clinical notes are generated using a structured prompting pipeline grounded in diagnostic reasoning, then perturbed along four axes: masking, negation, synonym replacement, and numeric variation to simulate common ambiguities and omissions. We compute LDFR across both foundation and clinical LLMs, finding that latent fragility emerges even under minimal surface-level changes. Finally, we validate our findings on 90 real clinical notes from the DiReCT benchmark (MIMIC-IV), confirming the generalizability of LDFR beyond synthetic settings. Our results reveal a persistent gap between surface robustness and semantic stability, underscoring the importance of geometry-aware auditing in safety-critical clinical AI.

With the emergence of large-scale vision language models (VLM), it is now possible to produce realistic-looking radiology reports for chest X-ray images. However, their clinical translation has been hampered by the factual errors and hallucinations in the produced descriptions during inference. In this paper, we present a novel phrase-grounded fact-checking model (FC model) that detects errors in findings and their indicated locations in automatically generated chest radiology reports. Specifically, we simulate the errors in reports through a large synthetic dataset derived by perturbing findings and their locations in ground truth reports to form real and fake findings-location pairs with images. A new multi-label cross-modal contrastive regression network is then trained on this dataset. We present results demonstrating the robustness of our method in terms of accuracy of finding veracity prediction and localization on multiple X-ray datasets. We also show its effectiveness for error detection in reports of SOTA report generators on multiple datasets achieving a concordance correlation coefficient of 0.997 with ground truth-based verification, thus pointing to its utility during clinical inference in radiology workflows.

This paper takes a first step towards a critical thinking curriculum for neural auto-regressive language models. We introduce a synthetic corpus of deductively valid arguments, and generate artificial argumentative texts to train and evaluate GPT-2. Significant transfer learning effects can be observed: Training a model on three simple core schemes allows it to accurately complete conclusions of different, and more complex types of arguments, too. The language models generalize the core argument schemes in a correct way. Moreover, we obtain consistent and promising results for NLU benchmarks. In particular, pre-training on the argument schemes raises zero-shot accuracy on the GLUE diagnostics by up to 15 percentage points. The findings suggest that intermediary pre-training on texts that exemplify basic reasoning abilities (such as typically covered in critical thinking textbooks) might help language models to acquire a broad range of reasoning skills. The synthetic argumentative texts presented in this paper are a promising starting point for building such a "critical thinking curriculum for language models."

Misinformation in healthcare, from vaccine hesitancy to unproven treatments, poses risks to public health and trust in medical systems. While machine learning and natural language processing have advanced automated fact-checking, validating biomedical claims remains uniquely challenging due to complex terminology, the need for domain expertise, and the critical importance of grounding in scientific evidence. We introduce CER (Combining Evidence and Reasoning), a novel framework for biomedical fact-checking that integrates scientific evidence retrieval, reasoning via large language models, and supervised veracity prediction. By integrating the text-generation capabilities of large language models with advanced retrieval techniques for high-quality biomedical scientific evidence, CER effectively mitigates the risk of hallucinations, ensuring that generated outputs are grounded in verifiable, evidence-based sources. Evaluations on expert-annotated datasets (HealthFC, BioASQ-7b, SciFact) demonstrate state-of-the-art performance and promising cross-dataset generalization. Code and data are released for transparency and reproducibility: https: //github.com/PRAISELab-PicusLab/CER.

Assessing journal legitimacy during literature reviews, publication venue selection, and citation verification requires consulting information scattered across multiple incompatible data-sets. This paper introduces Aletheia-Probe, an open-source tool that systematically aggregates curated databases and pattern analysis from multiple authoritative sources to provide transparent, confidence-scored journal assessments. The tool explicitly reports which sources were consulted, what each found, and where evidence conflicts. The tool integrates into research workflows through command-line and programmatic interfaces. It reduces manual assessment overhead while explicitly flagging uncertain cases. We present the tool's architecture, core design principles, and practical integration approach. Comprehensive empirical validation will be presented in forthcoming work.

Misinformation about climate change is a complex societal issue requiring holistic, interdisciplinary solutions at the intersection between technology and psychology. One proposed solution is a "technocognitive" approach, involving the synthesis of psychological and computer science research. Psychological research has identified that interventions in response to misinformation require both fact-based (e.g., factual explanations) and technique-based (e.g., explanations of misleading techniques) content. However, little progress has been made on documenting and detecting fallacies in climate misinformation. In this study, we apply a previously developed critical thinking methodology for deconstructing climate misinformation, in order to develop a dataset mapping different types of climate misinformation to reasoning fallacies. This dataset is used to train a model to detect fallacies in climate misinformation. Our study shows F1 scores that are 2.5 to 3.5 better than previous works. The fallacies that are easiest to detect include fake experts and anecdotal arguments, while fallacies that require background knowledge, such as oversimplification, misrepresentation, and slothful induction, are relatively more difficult to detect. This research lays the groundwork for development of solutions where automatically detected climate misinformation can be countered with generative technique-based corrections.

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic reasoning abilities of medical large language models (LLMs) have not been rigorously evaluated. To address these gaps, we present MedDialogRubrics, a novel benchmark comprising 5,200 synthetically constructed patient cases and over 60,000 fine-grained evaluation rubrics generated by LLMs and subsequently refined by clinical experts, specifically designed to assess the multi-turn diagnostic capabilities of LLM. Our framework employs a multi-agent system to synthesize realistic patient records and chief complaints from underlying disease knowledge without accessing real-world electronic health records, thereby mitigating privacy and data-governance concerns. We design a robust Patient Agent that is limited to a set of atomic medical facts and augmented with a dynamic guidance mechanism that continuously detects and corrects hallucinations throughout the dialogue, ensuring internal coherence and clinical plausibility of the simulated cases. Furthermore, we propose a structured LLM-based and expert-annotated rubric-generation pipeline that retrieves Evidence-Based Medicine (EBM) guidelines and utilizes the reject sampling to derive a prioritized set of rubric items ("must-ask" items) for each case. We perform a comprehensive evaluation of state-of-the-art models and demonstrate that, across multiple assessment dimensions, current models face substantial challenges. Our results indicate that improving medical dialogue will require advances in dialogue management architectures, not just incremental tuning of the base-model.

In this paper, we present our submission to the MM-ArgFallacy2025 shared task, which aims to advance research in multimodal argument mining, focusing on logical fallacies in political debates. Our approach uses pretrained Transformer-based models and proposes several ways to leverage context. In the fallacy classification subtask, our models achieved macro F1-scores of 0.4444 (text), 0.3559 (audio), and 0.4403 (multimodal). Our multimodal model showed performance comparable to the text-only model, suggesting potential for improvements.

Large Language Models (LLMs) have shown impressive performance in reasoning tasks. However, LLMs tend to generate excessively long reasoning content, leading to significant computational overhead. Our observations indicate that even on simple problems, LLMs tend to produce unnecessarily lengthy reasoning content, which is against intuitive expectations. Preliminary experiments show that at a certain point during the generation process, the model is already capable of producing the correct solution without completing the full reasoning content. Therefore, we consider that the reasoning process of the model can be exited early to achieve the purpose of efficient reasoning. We introduce a verification model that identifies the exact moment when the model can stop reasoning and still provide the correct answer. Comprehensive experiments on four different benchmarks demonstrate that our proposed method, FlashThink, effectively shortens the reasoning content while preserving the model accuracy. For the Deepseek-R1 and QwQ-32B models, we reduced the length of reasoning content by 77.04% and 77.47%, respectively, without reducing the accuracy.

Large language model (LLM)-based reasoning systems have recently achieved gold medal-level performance in the IMO 2025 competition, writing mathematical proofs where, to receive full credit, each step must be not only correct but also sufficiently supported. To train LLM-based reasoners in such challenging, open-ended settings, strong verifiers capable of catching step-level mistakes are necessary prerequisites. We introduce Hard2Verify, a human-annotated, step-level verification benchmark produced with over 500 hours of human labor. Hard2Verify is designed to rigorously assess step-level verifiers at the frontier: Verifiers must provide step-level annotations or identify the first error in responses generated by frontier LLMs for very recent, challenging, and open-ended math questions. We evaluate 29 generative critics and process reward models, demonstrating that, beyond a few standouts, open-source verifiers lag closed source models. We subsequently analyze what drives poor performance in step-level verification, the impacts of scaling verifier compute, as well as fundamental questions such as self-verification and verification-generation dynamics.

Current large language models (LLMs) often suffer from hallucination issues, i,e, generating content that appears factual but is actually unreliable. A typical hallucination detection pipeline involves response decomposition (i.e., claim extraction), query generation, evidence collection (i.e., search or retrieval), and claim verification. However, existing methods exhibit limitations in the first two stages, such as context loss during claim extraction and low specificity in query generation, resulting in degraded performance across the hallucination detection pipeline. In this work, we introduce JointCQ https://github.com/pku0xff/JointCQ, a joint claim-and-query generation framework designed to construct an effective and efficient claim-query generator. Our framework leverages elaborately designed evaluation criteria to filter synthesized training data, and finetunes a language model for joint claim extraction and query generation, providing reliable and informative inputs for downstream search and verification. Experimental results demonstrate that our method outperforms previous methods on multiple open-domain QA hallucination detection benchmarks, advancing the goal of more trustworthy and transparent language model systems.

With the growing importance of detecting misinformation, many studies have focused on verifying factual claims by retrieving evidence. However, canonical fact verification tasks do not apply to catching subtle differences in factually consistent claims, which might still bias the readers, especially on contentious political or economic issues. Our underlying assumption is that among the trusted sources, one's argument is not necessarily more true than the other, requiring comparison rather than verification. In this study, we propose ClaimDiff, a novel dataset that primarily focuses on comparing the nuance between claim pairs. In ClaimDiff, we provide 2,941 annotated claim pairs from 268 news articles. We observe that while humans are capable of detecting the nuances between claims, strong baselines struggle to detect them, showing over a 19% absolute gap with the humans. We hope this initial study could help readers to gain an unbiased grasp of contentious issues through machine-aided comparison.

In this paper, we present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn diagnostic processes, adaptively select examinations, and commit to final diagnoses. Unlike instruction-tuned models trained on static case summaries, our method acquires diagnostic strategies through interactive exploration and outcome-based feedback. Our contributions are fourfold: (i) We present DiagGym, a diagnostics world model trained with electronic health records that emits examination outcomes conditioned on patient history and recommended examination, serving as a virtual clinical environment for realistic diagnosis training and evaluation; (ii) We train DiagAgent via end-to-end, multi-turn reinforcement learning to learn diagnostic policies that optimize both information yield and diagnostic accuracy; (iii) We introduce DiagBench, a diagnostic benchmark comprising 750 cases with physician-validated examination recommendations and 99 cases annotated with 973 physician-written rubrics on diagnosis process; (iv) we demonstrate superior performance across diverse diagnostic settings. DiagAgent significantly outperforms 10 state-of-the-art LLMs, including DeepSeek-v3 and GPT-4o, as well as two prompt-engineered agents. In single-turn settings, DiagAgent achieves 9.34% higher diagnostic accuracy and 44.03% improvement in examination recommendation hit ratio. In end-to-end settings, it delivers 15.12% increase in diagnostic accuracy and 23.09% boost in examination recommendation F1 score. In rubric-based evaluation, it surpasses the next-best model, Claude-sonnet-4, by 7.1% in weighted rubric score. These findings indicate that learning policies in interactive clinical environments confers dynamic and clinically meaningful diagnostic management abilities unattainable through passive training alone.

The automated detection of conspiracy theories online typically relies on supervised learning. However, creating respective training data requires expertise, time and mental resilience, given the often harmful content. Moreover, available datasets are predominantly in English and often keyword-based, introducing a token-level bias into the models. Our work addresses the task of detecting conspiracy theories in German Telegram messages. We compare the performance of supervised fine-tuning approaches using BERT-like models with prompt-based approaches using Llama2, GPT-3.5, and GPT-4 which require little or no additional training data. We use a dataset of sim!! 4,000 messages collected during the COVID-19 pandemic, without the use of keyword filters. Our findings demonstrate that both approaches can be leveraged effectively: For supervised fine-tuning, we report an F1 score of sim!! 0.8 for the positive class, making our model comparable to recent models trained on keyword-focused English corpora. We demonstrate our model's adaptability to intra-domain temporal shifts, achieving F1 scores of sim!! 0.7. Among prompting variants, the best model is GPT-4, achieving an F1 score of sim!! 0.8 for the positive class in a zero-shot setting and equipped with a custom conspiracy theory definition.

We introduce MentalBench, a benchmark for evaluating psychiatric diagnostic decision-making in large language models (LLMs). Existing mental health benchmarks largely rely on social media data, limiting their ability to assess DSM-grounded diagnostic judgments. At the core of MentalBench is MentalKG, a psychiatrist-built and validated knowledge graph encoding DSM-5 diagnostic criteria and differential diagnostic rules for 23 psychiatric disorders. Using MentalKG as a golden-standard logical backbone, we generate 24,750 synthetic clinical cases that systematically vary in information completeness and diagnostic complexity, enabling low-noise and interpretable evaluation. Our experiments show that while state-of-the-art LLMs perform well on structured queries probing DSM-5 knowledge, they struggle to calibrate confidence in diagnostic decision-making when distinguishing between clinically overlapping disorders. These findings reveal evaluation gaps not captured by existing benchmarks.

Given a natural language statement, how to verify its veracity against a large-scale textual knowledge source like Wikipedia? Most existing neural models make predictions without giving clues about which part of a false claim goes wrong. In this paper, we propose LOREN, an approach for interpretable fact verification. We decompose the verification of the whole claim at phrase-level, where the veracity of the phrases serves as explanations and can be aggregated into the final verdict according to logical rules. The key insight of LOREN is to represent claim phrase veracity as three-valued latent variables, which are regularized by aggregation logical rules. The final claim verification is based on all latent variables. Thus, LOREN enjoys the additional benefit of interpretability -- it is easy to explain how it reaches certain results with claim phrase veracity. Experiments on a public fact verification benchmark show that LOREN is competitive against previous approaches while enjoying the merit of faithful and accurate interpretability. The resources of LOREN are available at: https://github.com/jiangjiechen/LOREN.

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face scarce real world electronic health records (EHRs), stale domain knowledge, and hallucinations. We assemble a large, domain specialized clinical corpus and a clinician validated reasoning set, and develop RareSeek R1 via staged instruction tuning, chain of thought learning, and graph grounded retrieval. Across multicenter EHR narratives and public benchmarks, RareSeek R1 attains state of the art accuracy, robust generalization, and stability under noisy or overlapping phenotypes. Augmented retrieval yields the largest gains when narratives pair with prioritized variants by resolving ambiguity and aligning candidates to mechanisms. Human studies show performance on par with experienced physicians and consistent gains in assistive use. Notably, transparent reasoning highlights decisive non phenotypic evidence (median 23.1%, such as imaging, interventions, functional tests) underpinning many correct diagnoses. This work advances a narrative first, knowledge integrated reasoning paradigm that shortens the diagnostic odyssey and enables auditable, clinically translatable decision support.

Large language models (LLMs) frequently generate non-factual content, known as hallucinations. Existing retrieval-augmented-based hallucination detection approaches typically address this by framing it as a classification task, evaluating hallucinations based on their consistency with retrieved evidence. However, this approach usually lacks detailed explanations for these evaluations and does not assess the reliability of these explanations. Furthermore, deficiencies in retrieval systems can lead to irrelevant or partially relevant evidence retrieval, impairing the detection process. Moreover, while real-world hallucination detection requires analyzing multiple pieces of evidence, current systems usually treat all evidence uniformly without considering its relevance to the content. To address these challenges, we introduce Halu-J, a critique-based hallucination judge with 7 billion parameters. Halu-J enhances hallucination detection by selecting pertinent evidence and providing detailed critiques. Our experiments indicate that Halu-J outperforms GPT-4o in multiple-evidence hallucination detection and matches its capability in critique generation and evidence selection. We also introduce ME-FEVER, a new dataset designed for multiple-evidence hallucination detection. Our code and dataset can be found in https://github.com/GAIR-NLP/factool .

When building artificial intelligence systems that can reason and answer questions about visual data, we need diagnostic tests to analyze our progress and discover shortcomings. Existing benchmarks for visual question answering can help, but have strong biases that models can exploit to correctly answer questions without reasoning. They also conflate multiple sources of error, making it hard to pinpoint model weaknesses. We present a diagnostic dataset that tests a range of visual reasoning abilities. It contains minimal biases and has detailed annotations describing the kind of reasoning each question requires. We use this dataset to analyze a variety of modern visual reasoning systems, providing novel insights into their abilities and limitations.

Scientific texts often convey authority due to their technical language and complex data. However, this complexity can sometimes lead to the spread of misinformation. Non-experts are particularly susceptible to misleading claims based on scientific tables due to their high information density and perceived credibility. Existing table claim verification models, including state-of-the-art large language models (LLMs), often struggle with precise fine-grained reasoning, resulting in errors and a lack of precision in verifying scientific claims. Inspired by Cognitive Load Theory, we propose that enhancing a model's ability to interpret table-based claims involves reducing cognitive load by developing modular, reusable reasoning components (i.e., atomic skills). We introduce a skill-chaining schema that dynamically composes these skills to facilitate more accurate and generalizable reasoning with a reduced cognitive load. To evaluate this, we create SciAtomicBench, a cross-domain benchmark with fine-grained reasoning annotations. With only 350 fine-tuning examples, our model trained by atomic reasoning outperforms GPT-4o's chain-of-thought method, achieving state-of-the-art results with far less training data.

Current Chain-of-Thought (CoT) verification methods predict reasoning correctness based on outputs (black-box) or activations (gray-box), but offer limited insight into why a computation fails. We introduce a white-box method: Circuit-based Reasoning Verification (CRV). We hypothesize that attribution graphs of correct CoT steps, viewed as execution traces of the model's latent reasoning circuits, possess distinct structural fingerprints from those of incorrect steps. By training a classifier on structural features of these graphs, we show that these traces contain a powerful signal of reasoning errors. Our white-box approach yields novel scientific insights unattainable by other methods. (1) We demonstrate that structural signatures of error are highly predictive, establishing the viability of verifying reasoning directly via its computational graph. (2) We find these signatures to be highly domain-specific, revealing that failures in different reasoning tasks manifest as distinct computational patterns. (3) We provide evidence that these signatures are not merely correlational; by using our analysis to guide targeted interventions on individual transcoder features, we successfully correct the model's faulty reasoning. Our work shows that, by scrutinizing a model's computational process, we can move from simple error detection to a deeper, causal understanding of LLM reasoning.

Large Language Models (LLMs) significantly benefit from Chain-of-Thought (CoT) prompting in performing various reasoning tasks. While CoT allows models to produce more comprehensive reasoning processes, its emphasis on intermediate reasoning steps can inadvertently introduce hallucinations and accumulated errors, thereby limiting models' ability to solve complex reasoning tasks. Inspired by how humans engage in careful and meticulous deductive logical reasoning processes to solve tasks, we seek to enable language models to perform explicit and rigorous deductive reasoning, and also ensure the trustworthiness of their reasoning process through self-verification. However, directly verifying the validity of an entire deductive reasoning process is challenging, even with advanced models like ChatGPT. In light of this, we propose to decompose a reasoning verification process into a series of step-by-step subprocesses, each only receiving their necessary context and premises. To facilitate this procedure, we propose Natural Program, a natural language-based deductive reasoning format. Our approach enables models to generate precise reasoning steps where subsequent steps are more rigorously grounded on prior steps. It also empowers language models to carry out reasoning self-verification in a step-by-step manner. By integrating this verification process into each deductive reasoning stage, we significantly enhance the rigor and trustfulness of generated reasoning steps. Along this process, we also improve the answer correctness on complex reasoning tasks. Code will be released at https://github.com/lz1oceani/verify_cot.

Fact-checking requires retrieving evidence related to a claim under investigation. The task can be formulated as question generation based on a claim, followed by question answering. However, recent question generation approaches assume that the answer is known and typically contained in a passage given as input, whereas such passages are what is being sought when verifying a claim. In this paper, we present {\it Varifocal}, a method that generates questions based on different focal points within a given claim, i.e.\ different spans of the claim and its metadata, such as its source and date. Our method outperforms previous work on a fact-checking question generation dataset on a wide range of automatic evaluation metrics. These results are corroborated by our manual evaluation, which indicates that our method generates more relevant and informative questions. We further demonstrate the potential of focal points in generating sets of clarification questions for product descriptions.

The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though distinct from mathematics, also demands robust reasoning to provide reliable answers, given the high standards of healthcare. However, verifying medical reasoning is challenging, unlike those in mathematics. To address this, we propose verifiable medical problems with a medical verifier to check the correctness of model outputs. This verifiable nature enables advancements in medical reasoning through a two-stage approach: (1) using the verifier to guide the search for a complex reasoning trajectory for fine-tuning LLMs, (2) applying reinforcement learning (RL) with verifier-based rewards to enhance complex reasoning further. Finally, we introduce HuatuoGPT-o1, a medical LLM capable of complex reasoning, which outperforms general and medical-specific baselines using only 40K verifiable problems. Experiments show complex reasoning improves medical problem-solving and benefits more from RL. We hope our approach inspires advancements in reasoning across medical and other specialized domains.