Daily Papers

Training deep networks and tuning hyperparameters on large datasets is computationally intensive. One of the primary research directions for efficient training is to reduce training costs by selecting well-generalizable subsets of training data. Compared to simple adaptive random subset selection baselines, existing intelligent subset selection approaches are not competitive due to the time-consuming subset selection step, which involves computing model-dependent gradients and feature embeddings and applies greedy maximization of submodular objectives. Our key insight is that removing the reliance on downstream model parameters enables subset selection as a pre-processing step and enables one to train multiple models at no additional cost. In this work, we propose MILO, a model-agnostic subset selection framework that decouples the subset selection from model training while enabling superior model convergence and performance by using an easy-to-hard curriculum. Our empirical results indicate that MILO can train models 3times - 10 times faster and tune hyperparameters 20times - 75 times faster than full-dataset training or tuning without compromising performance.

Low-rank adaptation (LoRA) and its mixture-of-experts (MOE) variants are highly effective parameter-efficient fine-tuning (PEFT) methods. However, they introduce significant latency in multi-tenant settings due to the LoRA modules and MOE routers added to multiple linear modules in the Transformer layer. To address this issue, we propose Mixture of Low-Rank Adaptation (MiLoRA), a novel and efficient LoRA variant. MiLoRA differs from previous MOE-style LoRA methods by considering each LoRA module as an expert and employing a prompt-aware routing mechanism. This mechanism calculates expert routing results once before generating the first new token and reuses these results for subsequent tokens, reducing latency. Extensive experiments and analysis on commonsense reasoning tasks, math reasoning tasks, and widely used LLM evaluation benchmarks demonstrate that MiLoRA consistently outperforms strong PEFT baselines with comparable tunable parameter budgets. Additionally, MiLoRA significantly reduces latency in multi-tenant settings compared to previous LoRA-based methods.

Efficient finetuning of large language models (LLMs) aims to adapt the LLMs with reduced computational and memory cost. Previous LoRA-based approaches initialize the low-rank matrices with Gaussian distribution and zero values while keeping the original weight matrices frozen. However, the trainable model parameters optimized in an unguided subspace might interfere with the well-learned subspace of the pretrained weight matrices. In this paper, we propose MiLoRA, a simple yet effective LLM finetuning approach that only updates the minor singular components of the weight matrix while keeping the principal singular components frozen. It is observed that the minor matrix corresponds to the noisy or long-tail information, while the principal matrix contains important knowledge. The MiLoRA initializes the low-rank matrices within a subspace that is orthogonal to the principal matrix, thus the pretrained knowledge is expected to be well preserved. During finetuning, MiLoRA makes the most use of the less-optimized subspace for learning the labeled dataset. Extensive experiments on commonsense reasoning, math reasoning, instruction following and visual instruction following benchmarks present the superior performance of our method.

We open-source MiMo-VL-Miloco-7B and its quantized variant MiMo-VL-Miloco-7B-GGUF, a pair of home-centric vision-language models that achieve strong performance on both home-scenario understanding and general multimodal reasoning. Built on the MiMo-VL-7B backbone, MiMo-VL-Miloco-7B is specialized for smart-home environments, attaining leading F1 scores on gesture recognition and common home-scenario understanding, while also delivering consistent gains across video benchmarks such as Video-MME, Video-MMMU, and Charades-STA, as well as language understanding benchmarks including MMMU-Pro and MMLU-Pro. In our experiments, MiMo-VL-Miloco-7B outperforms strong closed-source and open-source baselines on home-scenario understanding and several multimodal reasoning benchmarks. To balance specialization and generality, we design a two-stage training pipeline that combines supervised fine-tuning with reinforcement learning based on Group Relative Policy Optimization, leveraging efficient multi-domain data. We further incorporate chain-of-thought supervision and token-budget-aware reasoning, enabling the model to learn knowledge in a data-efficient manner while also performing reasoning efficiently. Our analysis shows that targeted home-scenario training not only enhances activity and gesture understanding, but also improves text-only reasoning with only modest trade-offs on document-centric tasks. Model checkpoints, quantized GGUF weights, and our home-scenario evaluation toolkit are publicly available at https://github.com/XiaoMi/xiaomi-mimo-vl-miloco to support research and deployment in real-world smart-home applications.

Echocardiography is the most widely used cardiac imaging modality, capturing ultrasound video data to assess cardiac structure and function. Artificial intelligence (AI) in echocardiography has the potential to streamline manual tasks and improve reproducibility and precision. However, most echocardiography AI models are single-view, single-task systems that do not synthesize complementary information from multiple views captured during a full exam, and thus lead to limited performance and scope of applications. To address this problem, we introduce EchoPrime, a multi-view, view-informed, video-based vision-language foundation model trained on over 12 million video-report pairs. EchoPrime uses contrastive learning to train a unified embedding model for all standard views in a comprehensive echocardiogram study with representation of both rare and common diseases and diagnoses. EchoPrime then utilizes view-classification and a view-informed anatomic attention model to weight video-specific interpretations that accurately maps the relationship between echocardiographic views and anatomical structures. With retrieval-augmented interpretation, EchoPrime integrates information from all echocardiogram videos in a comprehensive study and performs holistic comprehensive clinical echocardiography interpretation. In datasets from two independent healthcare systems, EchoPrime achieves state-of-the art performance on 23 diverse benchmarks of cardiac form and function, surpassing the performance of both task-specific approaches and prior foundation models. Following rigorous clinical evaluation, EchoPrime can assist physicians in the automated preliminary assessment of comprehensive echocardiography.

The development of deep learning software libraries enabled significant progress in the field by allowing users to focus on modeling, while letting the library to take care of the tedious and time-consuming task of optimizing execution for modern hardware accelerators. However, this has benefited only particular types of deep learning models, such as Transformers, whose primitives map easily to the vectorized computation. The models that explicitly account for structured objects, such as trees and segmentations, did not benefit equally because they require custom algorithms that are difficult to implement in a vectorized form. SynJax directly addresses this problem by providing an efficient vectorized implementation of inference algorithms for structured distributions covering alignment, tagging, segmentation, constituency trees and spanning trees. With SynJax we can build large-scale differentiable models that explicitly model structure in the data. The code is available at https://github.com/deepmind/synjax.

In this paper, we present the current progress of the project Verif.ai, an open-source scientific generative question-answering system with referenced and verified answers. The components of the system are (1) an information retrieval system combining semantic and lexical search techniques over scientific papers (PubMed), (2) a fine-tuned generative model (Mistral 7B) taking top answers and generating answers with references to the papers from which the claim was derived, and (3) a verification engine that cross-checks the generated claim and the abstract or paper from which the claim was derived, verifying whether there may have been any hallucinations in generating the claim. We are reinforcing the generative model by providing the abstract in context, but in addition, an independent set of methods and models are verifying the answer and checking for hallucinations. Therefore, we believe that by using our method, we can make scientists more productive, while building trust in the use of generative language models in scientific environments, where hallucinations and misinformation cannot be tolerated.

Supervised named entity recognition (NER) in the biomedical domain is dependent on large sets of annotated texts with the given named entities, whose creation can be time-consuming and expensive. Furthermore, the extraction of new entities often requires conducting additional annotation tasks and retraining the model. To address these challenges, this paper proposes a transformer-based method for zero- and few-shot NER in the biomedical domain. The method is based on transforming the task of multi-class token classification into binary token classification (token contains the searched entity or does not contain the searched entity) and pre-training on a larger amount of datasets and biomedical entities, from where the method can learn semantic relations between the given and potential classes. We have achieved average F1 scores of 35.44% for zero-shot NER, 50.10% for one-shot NER, 69.94% for 10-shot NER, and 79.51% for 100-shot NER on 9 diverse evaluated biomedical entities with PubMedBERT fine-tuned model. The results demonstrate the effectiveness of the proposed method for recognizing new entities with limited examples, with comparable or better results from the state-of-the-art zero- and few-shot NER methods.

Biomedical research is growing at such an exponential pace that scientists, researchers, and practitioners are no more able to cope with the amount of published literature in the domain. The knowledge presented in the literature needs to be systematized in such a way that claims and hypotheses can be easily found, accessed, and validated. Knowledge graphs can provide such a framework for semantic knowledge representation from literature. However, in order to build a knowledge graph, it is necessary to extract knowledge as relationships between biomedical entities and normalize both entities and relationship types. In this paper, we present and compare few rule-based and machine learning-based (Naive Bayes, Random Forests as examples of traditional machine learning methods and DistilBERT, PubMedBERT, T5 and SciFive-based models as examples of modern deep learning transformers) methods for scalable relationship extraction from biomedical literature, and for the integration into the knowledge graphs. We examine how resilient are these various methods to unbalanced and fairly small datasets. Our experiments show that transformer-based models handle well both small (due to pre-training on a large dataset) and unbalanced datasets. The best performing model was the PubMedBERT-based model fine-tuned on balanced data, with a reported F1-score of 0.92. DistilBERT-based model followed with F1-score of 0.89, performing faster and with lower resource requirements. BERT-based models performed better then T5-based generative models.

Accurate recognition of sign language in healthcare communication poses a significant challenge, requiring frameworks that can accurately interpret complex multimodal gestures. To deal with this, we propose FusionEnsemble-Net, a novel attention-based ensemble of spatiotemporal networks that dynamically fuses visual and motion data to enhance recognition accuracy. The proposed approach processes RGB video and range Doppler map radar modalities synchronously through four different spatiotemporal networks. For each network, features from both modalities are continuously fused using an attention-based fusion module before being fed into an ensemble of classifiers. Finally, the outputs of these four different fused channels are combined in an ensemble classification head, thereby enhancing the model's robustness. Experiments demonstrate that FusionEnsemble-Net outperforms state-of-the-art approaches with a test accuracy of 99.44% on the large-scale MultiMeDaLIS dataset for Italian Sign Language. Our findings indicate that an ensemble of diverse spatiotemporal networks, unified by attention-based fusion, yields a robust and accurate framework for complex, multimodal isolated gesture recognition tasks. The source code is available at: https://github.com/rezwanh001/Multimodal-Isolated-Italian-Sign-Language-Recognition.

With the advent of smart devices that support 4K and 8K resolution, Single Image Super Resolution (SISR) has become an important computer vision problem. However, most super resolution deep networks are computationally very expensive. In this paper, we propose Super-Efficient Super Resolution (SESR) networks that establish a new state-of-the-art for efficient super resolution. Our approach is based on linear overparameterization of CNNs and creates an efficient model architecture for SISR. With theoretical analysis, we uncover the limitations of existing overparameterization methods and show how the proposed method alleviates them. Detailed experiments across six benchmark datasets demonstrate that SESR achieves similar or better image quality than state-of-the-art models while requiring 2x to 330x fewer Multiply-Accumulate (MAC) operations. As a result, SESR can be used on constrained hardware to perform x2 (1080p to 4K) and x4 (1080p to 8K) SISR. Towards this, we estimate hardware performance numbers for a commercial Arm mobile-Neural Processing Unit (NPU) for 1080p to 4K (x2) and 1080p to 8K (x4) SISR. Our results highlight the challenges faced by super resolution on AI accelerators and demonstrate that SESR is significantly faster (e.g., 6x-8x higher FPS) than existing models on mobile-NPU. Finally, SESR outperforms prior models by 1.5x-2x in latency on Arm CPU and GPU when deployed on a real mobile device. The code for this work is available at https://github.com/ARM-software/sesr.

Relightable object acquisition is a key challenge in simplifying digital asset creation. Complete reconstruction of an object typically requires capturing hundreds to thousands of photographs under controlled illumination, with specialized equipment. The recent progress in differentiable rendering improved the quality and accessibility of inverse rendering optimization. Nevertheless, under uncontrolled illumination and unstructured viewpoints, there is no guarantee that the observations contain enough information to reconstruct the appearance properties of the captured object. We thus propose to consider the acquisition process from a signal-processing perspective. Given an object's geometry and a lighting environment, we estimate the properties of the materials on the object's surface in seconds. We do so by leveraging frequency domain analysis, considering the recovery of material properties as a deconvolution, enabling fast error estimation. We then quantify the uncertainty of the estimation, based on the available data, highlighting the areas for which priors or additional samples would be required for improved acquisition quality. We compare our approach to previous work and quantitatively evaluate our results, showing similar quality as previous work in a fraction of the time, and providing key information about the certainty of the results.

Microscopic assessment of histopathology images is vital for accurate cancer diagnosis and treatment. Whole Slide Image (WSI) classification and captioning have become crucial tasks in computer-aided pathology. However, microscopic WSI face challenges such as redundant patches and unknown patch positions due to subjective pathologist captures. Moreover, generating automatic pathology captions remains a significant challenge. To address these issues, we introduce a novel GNN-ViTCap framework for classification and caption generation from histopathological microscopic images. First, a visual feature extractor generates patch embeddings. Redundant patches are then removed by dynamically clustering these embeddings using deep embedded clustering and selecting representative patches via a scalar dot attention mechanism. We build a graph by connecting each node to its nearest neighbors in the similarity matrix and apply a graph neural network to capture both local and global context. The aggregated image embeddings are projected into the language model's input space through a linear layer and combined with caption tokens to fine-tune a large language model. We validate our method on the BreakHis and PatchGastric datasets. GNN-ViTCap achieves an F1 score of 0.934 and an AUC of 0.963 for classification, along with a BLEU-4 score of 0.811 and a METEOR score of 0.569 for captioning. Experimental results demonstrate that GNN-ViTCap outperforms state of the art approaches, offering a reliable and efficient solution for microscopy based patient diagnosis.

Continuous Sign Language Recognition (CSLR) faces multiple challenges, including significant inter-signer variability and poor generalization to novel sentence structures. Traditional solutions frequently fail to handle these issues efficiently. For overcoming these constraints, we propose a dual-architecture framework. For the Signer-Independent (SI) challenge, we propose a Signer-Invariant Conformer that combines convolutions with multi-head self-attention to learn robust, signer-agnostic representations from pose-based skeletal keypoints. For the Unseen-Sentences (US) task, we designed a Multi-Scale Fusion Transformer with a novel dual-path temporal encoder that captures both fine-grained posture dynamics, enabling the model's ability to comprehend novel grammatical compositions. Experiments on the challenging Isharah-1000 dataset establish a new standard for both CSLR benchmarks. The proposed conformer architecture achieves a Word Error Rate (WER) of 13.07% on the SI challenge, a reduction of 13.53% from the state-of-the-art. On the US task, the transformer model scores a WER of 47.78%, surpassing previous work. In the SignEval 2025 CSLR challenge, our team placed 2nd in the US task and 4th in the SI task, demonstrating the performance of these models. The findings validate our key hypothesis: that developing task-specific networks designed for the particular challenges of CSLR leads to considerable performance improvements and establishes a new baseline for further research. The source code is available at: https://github.com/rezwanh001/MSLR-Pose86K-CSLR-Isharah.

Depression is a major mental health condition that severely impacts the emotional and physical well-being of individuals. The simple nature of data collection from social media platforms has attracted significant interest in properly utilizing this information for mental health research. A Multimodal Depression Detection Network (MDD-Net), utilizing acoustic and visual data obtained from social media networks, is proposed in this work where mutual transformers are exploited to efficiently extract and fuse multimodal features for efficient depression detection. The MDD-Net consists of four core modules: an acoustic feature extraction module for retrieving relevant acoustic attributes, a visual feature extraction module for extracting significant high-level patterns, a mutual transformer for computing the correlations among the generated features and fusing these features from multiple modalities, and a detection layer for detecting depression using the fused feature representations. The extensive experiments are performed using the multimodal D-Vlog dataset, and the findings reveal that the developed multimodal depression detection network surpasses the state-of-the-art by up to 17.37% for F1-Score, demonstrating the greater performance of the proposed system. The source code is accessible at https://github.com/rezwanh001/Multimodal-Depression-Detection.

Depression is a serious mental health illness that significantly affects an individual's well-being and quality of life, making early detection crucial for adequate care and treatment. Detecting depression is often difficult, as it is based primarily on subjective evaluations during clinical interviews. Hence, the early diagnosis of depression, thanks to the content of social networks, has become a prominent research area. The extensive and diverse nature of user-generated information poses a significant challenge, limiting the accurate extraction of relevant temporal information and the effective fusion of data across multiple modalities. This paper introduces MMFformer, a multimodal depression detection network designed to retrieve depressive spatio-temporal high-level patterns from multimodal social media information. The transformer network with residual connections captures spatial features from videos, and a transformer encoder is exploited to design important temporal dynamics in audio. Moreover, the fusion architecture fused the extracted features through late and intermediate fusion strategies to find out the most relevant intermodal correlations among them. Finally, the proposed network is assessed on two large-scale depression detection datasets, and the results clearly reveal that it surpasses existing state-of-the-art approaches, improving the F1-Score by 13.92% for D-Vlog dataset and 7.74% for LMVD dataset. The code is made available publicly at https://github.com/rezwanh001/Large-Scale-Multimodal-Depression-Detection.

Scene-level 3D generation is a challenging research topic, with most existing methods generating only partial scenes and offering limited navigational freedom. We introduce WorldPrompter, a novel generative pipeline for synthesizing traversable 3D scenes from text prompts. We leverage panoramic videos as an intermediate representation to model the 360{\deg} details of a scene. WorldPrompter incorporates a conditional 360{\deg} panoramic video generator, capable of producing a 128-frame video that simulates a person walking through and capturing a virtual environment. The resulting video is then reconstructed as Gaussian splats by a fast feedforward 3D reconstructor, enabling a true walkable experience within the 3D scene. Experiments demonstrate that our panoramic video generation model achieves convincing view consistency across frames, enabling high-quality panoramic Gaussian splat reconstruction and facilitating traversal over an area of the scene. Qualitative and quantitative results also show it outperforms the state-of-the-art 360{\deg} video generators and 3D scene generation models.

Audio and speech coding lack unified evaluation and open-source testing. Many candidate systems were evaluated on proprietary, non-reproducible, or small data, and machine learning-based codecs are often tested on datasets with similar distributions as trained on, which is unfairly compared to digital signal processing-based codecs that usually work well with unseen data. This paper presents a full-band audio and speech coding quality benchmark with more variable content types, including traditional open test vectors. An example use case of audio coding quality assessment is presented with open-source Opus, 3GPP's EVS, and recent ETSI's LC3 with LC3+ used in Bluetooth LE Audio profiles. Besides, quality variations of emotional speech encoding at 16 kbps are shown. The proposed open-source benchmark contributes to audio and speech coding democratization and is available at https://github.com/JozefColdenhoff/OpenACE.

This work proposes a new pipeline for leveraging data collected on the Stack Overflow website for pre-training a multimodal model for searching duplicates on question answering websites. Our multimodal model is trained on question descriptions and source codes in multiple programming languages. We design two new learning objectives to improve duplicate detection capabilities. The result of this work is a mature, fine-tuned Multimodal Question Duplicity Detection (MQDD) model, ready to be integrated into a Stack Overflow search system, where it can help users find answers for already answered questions. Alongside the MQDD model, we release two datasets related to the software engineering domain. The first Stack Overflow Dataset (SOD) represents a massive corpus of paired questions and answers. The second Stack Overflow Duplicity Dataset (SODD) contains data for training duplicate detection models.

In this work we address the problem of landmark-based segmentation for anatomical structures. We propose HybridGNet, an encoder-decoder neural architecture which combines standard convolutions for image feature encoding, with graph convolutional neural networks to decode plausible representations of anatomical structures. We benchmark the proposed architecture considering other standard landmark and pixel-based models for anatomical segmentation in chest x-ray images, and found that HybridGNet is more robust to image occlusions. We also show that it can be used to construct landmark-based segmentations from pixel level annotations. Our experimental results suggest that HybridGNet produces accurate and anatomically plausible landmark-based segmentations, by naturally incorporating shape constraints within the decoding process via spectral convolutions.

Synthetic data generation with Large Language Models is a promising paradigm for augmenting natural data over a nearly infinite range of tasks. Given this variety, direct comparisons among synthetic data generation algorithms are scarce, making it difficult to understand where improvement comes from and what bottlenecks exist. We propose to evaluate algorithms via the makeup of synthetic data generated by each algorithm in terms of data quality, diversity, and complexity. We choose these three characteristics for their significance in open-ended processes and the impact each has on the capabilities of downstream models. We find quality to be essential for in-distribution model generalization, diversity to be essential for out-of-distribution generalization, and complexity to be beneficial for both. Further, we emphasize the existence of Quality-Diversity trade-offs in training data and the downstream effects on model performance. We then examine the effect of various components in the synthetic data pipeline on each data characteristic. This examination allows us to taxonomize and compare synthetic data generation algorithms through the components they utilize and the resulting effects on data QDC composition. This analysis extends into a discussion on the importance of balancing QDC in synthetic data for efficient reinforcement learning and self-improvement algorithms. Analogous to the QD trade-offs in training data, often there exist trade-offs between model output quality and output diversity which impact the composition of synthetic data. We observe that many models are currently evaluated and optimized only for output quality, thereby limiting output diversity and the potential for self-improvement. We argue that balancing these trade-offs is essential to the development of future self-improvement algorithms and highlight a number of works making progress in this direction.

Closed-loop brain stimulation refers to capturing neurophysiological measures such as electroencephalography (EEG), quickly identifying neural events of interest, and producing auditory, magnetic or electrical stimulation so as to interact with brain processes precisely. It is a promising new method for fundamental neuroscience and perhaps for clinical applications such as restoring degraded memory function; however, existing tools are expensive, cumbersome, and offer limited experimental flexibility. In this article, we propose the Portiloop, a deep learning-based, portable and low-cost closed-loop stimulation system able to target specific brain oscillations. We first document open-hardware implementations that can be constructed from commercially available components. We also provide a fast, lightweight neural network model and an exploration algorithm that automatically optimizes the model hyperparameters to the desired brain oscillation. Finally, we validate the technology on a challenging test case of real-time sleep spindle detection, with results comparable to off-line expert performance on the Massive Online Data Annotation spindle dataset (MODA; group consensus). Software and plans are available to the community as an open science initiative to encourage further development and advance closed-loop neuroscience research.

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is especially true for sensitive domains such as biomedicine, where there is a higher need for factually correct answers. This paper introduces a biomedical retrieval-augmented generation (RAG) system designed to enhance the reliability of generated responses. The system is based on a fine-tuned LLM for the referenced question-answering, where retrieved relevant abstracts from PubMed are passed to LLM's context as input through a prompt. Its output is an answer based on PubMed abstracts, where each statement is referenced accordingly, allowing the users to verify the answer. Our retrieval system achieves an absolute improvement of 23% compared to the PubMed search engine. Based on the manual evaluation on a small sample, our fine-tuned LLM component achieves comparable results to GPT-4 Turbo in referencing relevant abstracts. We make the dataset used to fine-tune the models and the fine-tuned models based on Mistral-7B-instruct-v0.1 and v0.2 publicly available.

Many popular programming languages, including C#, Java, and Python, support exceptions. Exceptions are thrown during program execution if an unwanted event happens, e.g., a method is invoked with an illegal argument value. Software developers write exceptional behavior tests (EBTs) to check that their code detects unwanted events and throws appropriate exceptions. Prior research studies have shown the importance of EBTs, but those studies also highlighted that developers put most of their efforts on "happy paths", e.g., paths without unwanted events. To help developers fill the gap, we present the first framework, dubbed exLong, that automatically generates EBTs. exLong is a large language model instruction-tuned from CodeLlama and embeds reasoning about traces that lead to throw statements, conditional expressions that guard throw statements, and non-exceptional behavior tests that execute similar traces. We compare exLong with the state-of-the-art models for test generation (CAT-LM) and one of the strongest foundation models (GPT3.5), as well as with analysis-based tools for test generation (Randoop and EvoSuite). Our results show that exLong outperforms existing models and tools. Furthermore, we contributed several pull requests to open-source projects and 23 EBTs generated by exLong were already accepted.

As large language models (LLMs) excel at code reasoning, a natural question arises: can an LLM execute programs (i.e., act as an interpreter) purely based on a programming language's formal semantics? If so, it will enable rapid prototyping of new programming languages and language features. We study this question using the imperative language IMP (a subset of C), formalized via small-step operational semantics (SOS) and rewriting-based operational semantics (K-semantics). We introduce three evaluation sets-Human-Written, LLM-Translated, and Fuzzer- Generated-whose difficulty is controlled by code-complexity metrics spanning the size, control-flow, and data-flow axes. Given a program and its semantics formalized with SOS/K-semantics, models are evaluated on three tasks ranging from coarse to fine: (1) final-state prediction, (2) semantic rule prediction, and (3) execution trace prediction. To distinguish pretraining memorization from semantic competence, we define two nonstandard semantics obtained through systematic mutations of the standard rules. Across strong code/reasoning LLMs, performance drops under nonstandard semantics despite high performance under the standard one. We further find that (i) there are patterns to different model failures, (ii) most reasoning models perform exceptionally well on coarse grained tasks involving reasoning about highly complex programs often containing nested loop depths beyond five, and surprisingly, (iii) providing formal semantics helps on simple programs but often hurts on more complex ones. Overall, the results show a promise that LLMs could serve as programming language interpreters, but points to the lack of their robust semantics understanding. We release the benchmark and the supporting code at https://github.com/EngineeringSoftware/PLSemanticsBench.

In recent years, Large Language Models (LLM) such as ChatGPT, CoPilot, and Gemini have been widely adopted in different areas. As the use of LLMs continues to grow, many efforts have focused on reducing the massive training overheads of these models. But it is the environmental impact of handling user requests to LLMs that is increasingly becoming a concern. Recent studies estimate that the costs of operating LLMs in their inference phase can exceed training costs by 25x per year. As LLMs are queried incessantly, the cumulative carbon footprint for the operational phase has been shown to far exceed the footprint during the training phase. Further, estimates indicate that 500 ml of fresh water is expended for every 20-50 requests to LLMs during inference. To address these important sustainability issues with LLMs, we propose a novel framework called SLIT to co-optimize LLM quality of service (time-to-first token), carbon emissions, water usage, and energy costs. The framework utilizes a machine learning (ML) based metaheuristic to enhance the sustainability of LLM hosting across geo-distributed cloud datacenters. Such a framework will become increasingly vital as LLMs proliferate.

Mixture of experts (MoE) models achieve state-of-the-art results in language modeling but suffer from inefficient hardware utilization due to imbalanced token routing and communication overhead. While prior work has focused on optimizing MoE training and decoder architectures, inference for encoder-based MoE models in a multi-GPU with expert parallelism setting remains underexplored. We introduce MoEShard, an inference system that achieves perfect load balancing through tensor sharding of MoE experts. Unlike existing approaches that rely on heuristic capacity factors or drop tokens, MoEShard evenly distributes computation across GPUs and ensures full token retention, maximizing utilization regardless of routing skewness. We achieve this through a strategic row- and column-wise decomposition of expert matrices. This reduces idle time and avoids bottlenecks caused by imbalanced expert assignments. Furthermore, MoEShard minimizes kernel launches by fusing decomposed expert computations, significantly improving throughput. We evaluate MoEShard against DeepSpeed on encoder-based architectures, demonstrating speedups of up to 6.4times in time to first token (TTFT). Our results show that tensor sharding, when properly applied to experts, is a viable and effective strategy for efficient MoE inference.

Recent work with JWST has demonstrated its capability to identify and chemically characterize multiple populations in globular clusters down to the H-burning limit. In this study, we explore the kinematics of multiple populations in the globular cluster 47 Tucanae by combining data from JWST, HST, and Gaia. We analyzed velocity dispersion and anisotropy profiles from the cluster center out to sim10R_h. Our findings indicate that while 1G stars are isotropic, 2G stars are significantly radially anisotropic. These results align with the predictions of simulations of the dynamical evolution of clusters where 2G stars are initially more centrally concentrated than 1G stars. Furthermore, we subdivided the 2G population into two subpopulations: 2G_A and 2G_B, with the latter being more chemically extreme. We compared their dynamical profiles and found no significant differences. For the first time, we measured the degree of energy equipartition among the multiple populations of 47 Tucanae. Overall, within the analyzed radial range (sim2-4R_h), both populations exhibit a low degree of energy equipartition. The most significant differences between 1G and 2G stars are observed in the tangential velocity component, where 2G stars are characterized by a stronger degree of energy equipartition than 1G stars. In the radial component, the behavior of 1G and 2G stars is more variable, with differences largely dependent on radius. Finally, our analysis reveals that the ratio of rotational velocity to velocity dispersion is larger for the 2G population, while 1G stars exhibit higher skewness in their tangential proper motions, providing further evidence of differences in the kinematic properties of the 1G and 2G populations.

We present Buffer Anytime, a framework for estimation of depth and normal maps (which we call geometric buffers) from video that eliminates the need for paired video--depth and video--normal training data. Instead of relying on large-scale annotated video datasets, we demonstrate high-quality video buffer estimation by leveraging single-image priors with temporal consistency constraints. Our zero-shot training strategy combines state-of-the-art image estimation models based on optical flow smoothness through a hybrid loss function, implemented via a lightweight temporal attention architecture. Applied to leading image models like Depth Anything V2 and Marigold-E2E-FT, our approach significantly improves temporal consistency while maintaining accuracy. Experiments show that our method not only outperforms image-based approaches but also achieves results comparable to state-of-the-art video models trained on large-scale paired video datasets, despite using no such paired video data.

3D Gaussian Splatting (3DGS) has shown its impressive power in novel view synthesis. However, creating relightable 3D assets, especially for objects with ill-defined shapes (e.g., fur), is still a challenging task. For these scenes, the decomposition between the light, geometry, and material is more ambiguous, as neither the surface constraints nor the analytical shading model hold. To address this issue, we propose RNG, a novel representation of relightable neural Gaussians, enabling the relighting of objects with both hard surfaces or fluffy boundaries. We avoid any assumptions in the shading model but maintain feature vectors, which can be further decoded by an MLP into colors, in each Gaussian point. Following prior work, we utilize a point light to reduce the ambiguity and introduce a shadow-aware condition to the network. We additionally propose a depth refinement network to help the shadow computation under the 3DGS framework, leading to better shadow effects under point lights. Furthermore, to avoid the blurriness brought by the alpha-blending in 3DGS, we design a hybrid forward-deferred optimization strategy. As a result, we achieve about 20times faster in training and about 600times faster in rendering than prior work based on neural radiance fields, with 60 frames per second on an RTX4090.

This study investigates the metacognitive capabilities of Large Language Models relative to human metacognition in the context of the International Coaching Federation ICF mimicking exam, a situational judgment test related to coaching competencies. Using a mixed method approach, we assessed the metacognitive performance, including sensitivity, accuracy in probabilistic predictions, and bias, of human participants and five advanced LLMs (GPT-4, Claude-3-Opus 3, Mistral Large, Llama 3, and Gemini 1.5 Pro). The results indicate that LLMs outperformed humans across all metacognitive metrics, particularly in terms of reduced overconfidence, compared to humans. However, both LLMs and humans showed less adaptability in ambiguous scenarios, adhering closely to predefined decision frameworks. The study suggests that Generative AI can effectively engage in human-like metacognitive processing without conscious awareness. Implications of the study are discussed in relation to development of AI simulators that scaffold cognitive and metacognitive aspects of mastering coaching competencies. More broadly, implications of these results are discussed in relation to development of metacognitive modules that lead towards more autonomous and intuitive AI systems.

The development of successful artificial intelligence models for chest X-ray analysis relies on large, diverse datasets with high-quality annotations. While several databases of chest X-ray images have been released, most include disease diagnosis labels but lack detailed pixel-level anatomical segmentation labels. To address this gap, we introduce an extensive chest X-ray multi-center segmentation dataset with uniform and fine-grain anatomical annotations for images coming from six well-known publicly available databases: CANDID-PTX, ChestX-ray8, Chexpert, MIMIC-CXR-JPG, Padchest, and VinDr-CXR, resulting in 676,803 segmentation masks. Our methodology utilizes the HybridGNet model to ensure consistent and high-quality segmentations across all datasets. Rigorous validation, including expert physician evaluation and automatic quality control, was conducted to validate the resulting masks. Additionally, we provide individualized quality indices per mask and an overall quality estimation per dataset. This dataset serves as a valuable resource for the broader scientific community, streamlining the development and assessment of innovative methodologies in chest X-ray analysis. The CheXmask dataset is publicly available at: https://physionet.org/content/chexmask-cxr-segmentation-data/.

Writing tests is a time-consuming yet essential task during software development. We propose to leverage recent advances in deep learning for text and code generation to assist developers in writing tests. We formalize the novel task of test completion to automatically complete the next statement in a test method based on the context of prior statements and the code under test. We develop TeCo -- a deep learning model using code semantics for test completion. The key insight underlying TeCo is that predicting the next statement in a test method requires reasoning about code execution, which is hard to do with only syntax-level data that existing code completion models use. TeCo extracts and uses six kinds of code semantics data, including the execution result of prior statements and the execution context of the test method. To provide a testbed for this new task, as well as to evaluate TeCo, we collect a corpus of 130,934 test methods from 1,270 open-source Java projects. Our results show that TeCo achieves an exact-match accuracy of 18, which is 29% higher than the best baseline using syntax-level data only. When measuring functional correctness of generated next statement, TeCo can generate runnable code in 29% of the cases compared to 18% obtained by the best baseline. Moreover, TeCo is significantly better than prior work on test oracle generation.

Learning anatomical segmentation from heterogeneous labels in multi-center datasets is a common situation encountered in clinical scenarios, where certain anatomical structures are only annotated in images coming from particular medical centers, but not in the full database. Here we first show how state-of-the-art pixel-level segmentation models fail in naively learning this task due to domain memorization issues and conflicting labels. We then propose to adopt HybridGNet, a landmark-based segmentation model which learns the available anatomical structures using graph-based representations. By analyzing the latent space learned by both models, we show that HybridGNet naturally learns more domain-invariant feature representations, and provide empirical evidence in the context of chest X-ray multiclass segmentation. We hope these insights will shed light on the training of deep learning models with heterogeneous labels from public and multi-center datasets.

Natural language processing (NLP) is an area of artificial intelligence that applies information technologies to process the human language, understand it to a certain degree, and use it in various applications. This area has rapidly developed in the last few years and now employs modern variants of deep neural networks to extract relevant patterns from large text corpora. The main objective of this work is to survey the recent use of NLP in the field of pharmacology. As our work shows, NLP is a highly relevant information extraction and processing approach for pharmacology. It has been used extensively, from intelligent searches through thousands of medical documents to finding traces of adversarial drug interactions in social media. We split our coverage into five categories to survey modern NLP methodology, commonly addressed tasks, relevant textual data, knowledge bases, and useful programming libraries. We split each of the five categories into appropriate subcategories, describe their main properties and ideas, and summarize them in a tabular form. The resulting survey presents a comprehensive overview of the area, useful to practitioners and interested observers.

Previous studies have shown that automated text-mining tools are becoming increasingly important for successfully unlocking variant information in scientific literature at large scale. Despite multiple attempts in the past, existing tools are still of limited recognition scope and precision. We propose tmVar 3.0: an improved variant recognition and normalization tool. Compared to its predecessors, tmVar 3.0 is able to recognize a wide spectrum of variant related entities (e.g., allele and copy number variants), and to group different variant mentions belonging to the same concept in an article for improved accuracy. Moreover, tmVar3 provides additional variant normalization options such as allele-specific identifiers from the ClinGen Allele Registry. tmVar3 exhibits a state-of-the-art performance with over 90% accuracy in F-measure in variant recognition and normalization, when evaluated on three independent benchmarking datasets. tmVar3 is freely available for download. We have also processed the entire PubMed and PMC with tmVar3 and released its annotations on our FTP. Availability: ftp://ftp.ncbi.nlm.nih.gov/pub/lu/tmVar3

Anatomical segmentation is a fundamental task in medical image computing, generally tackled with fully convolutional neural networks which produce dense segmentation masks. These models are often trained with loss functions such as cross-entropy or Dice, which assume pixels to be independent of each other, thus ignoring topological errors and anatomical inconsistencies. We address this limitation by moving from pixel-level to graph representations, which allow to naturally incorporate anatomical constraints by construction. To this end, we introduce HybridGNet, an encoder-decoder neural architecture that leverages standard convolutions for image feature encoding and graph convolutional neural networks (GCNNs) to decode plausible representations of anatomical structures. We also propose a novel image-to-graph skip connection layer which allows localized features to flow from standard convolutional blocks to GCNN blocks, and show that it improves segmentation accuracy. The proposed architecture is extensively evaluated in a variety of domain shift and image occlusion scenarios, and audited considering different types of demographic domain shift. Our comprehensive experimental setup compares HybridGNet with other landmark and pixel-based models for anatomical segmentation in chest x-ray images, and shows that it produces anatomically plausible results in challenging scenarios where other models tend to fail.

This paper describes the training process of the first Czech monolingual language representation models based on BERT and ALBERT architectures. We pre-train our models on more than 340K of sentences, which is 50 times more than multilingual models that include Czech data. We outperform the multilingual models on 9 out of 11 datasets. In addition, we establish the new state-of-the-art results on nine datasets. At the end, we discuss properties of monolingual and multilingual models based upon our results. We publish all the pre-trained and fine-tuned models freely for the research community.

We investigate the foreground interstellar medium along the line of sight and intracluster medium of omega Centauri (omega Cen) by measuring the equivalent width of Na I D absorptions from MUSE observations. The large line-of-sight velocity difference between omega Cen and the foreground enables us to separate Na I D absorption contributed from atomic gas in the interstellar and intracluster medium. We find that small-scale substructures in the foreground Na I D distribution correlate with differential reddening derived from photometric methods. Using an empirical Na I D equivalent width-reddening relation, we determine an average reddening of E(B-V)=0.153pm0.003 mag within the half-light radius of omega Cen. However, the Na I D-inferred differential reddening is significantly larger than photometric estimates. This is likely due to scatter in the Na I D-reddening relation. We find no evidence for intracluster atomic gas from spectra of horizontal branch stars, as there is no significant Na I D absorption at omega Cen's systemic velocity. Given this non-detection, we place the strongest upper limit to date on the intracluster atomic gas column density in omega Cen of lesssim2.17 times 10^{18}~cm^{-2}. We also estimate the ionized gas density from pulsar dispersion measure variations, which exceed the atomic gas limit by sim50 times. Nevertheless, the strong correlation between dispersion measure and foreground Na I D suggests that much or all of this ionized gas resides in the foreground. Given ongoing mass loss from bright giant stars, our findings imply that the intracluster gas accumulation timescale is short, and gas removal in the cluster is likely not tied to stripping as omega Cen passes through the Galactic disk.

In recent years, the application of machine learning to minimally invasive surgery (MIS) has attracted considerable interest. Datasets are critical to the use of such techniques. This paper presents a unique dataset recorded during ex vivo pseudo-cholecystectomy procedures on pig livers using the da Vinci Research Kit (dVRK). Unlike existing datasets, it addresses a critical gap by providing comprehensive kinematic data, recordings of all pedal inputs, and offers a time-stamped record of the endoscope's movements. This expanded version also includes segmentation and keypoint annotations of images, enhancing its utility for computer vision applications. Contributed by seven surgeons with varied backgrounds and experience levels that are provided as a part of this expanded version, the dataset is an important new resource for surgical robotics research. It enables the development of advanced methods for evaluating surgeon skills, tools for providing better context awareness, and automation of surgical tasks. Our work overcomes the limitations of incomplete recordings and imprecise kinematic data found in other datasets. To demonstrate the potential of the dataset for advancing automation in surgical robotics, we introduce two models that predict clutch usage and camera activation, a 3D scene reconstruction example, and the results from our keypoint and segmentation models.

We propose RelitLRM, a Large Reconstruction Model (LRM) for generating high-quality Gaussian splatting representations of 3D objects under novel illuminations from sparse (4-8) posed images captured under unknown static lighting. Unlike prior inverse rendering methods requiring dense captures and slow optimization, often causing artifacts like incorrect highlights or shadow baking, RelitLRM adopts a feed-forward transformer-based model with a novel combination of a geometry reconstructor and a relightable appearance generator based on diffusion. The model is trained end-to-end on synthetic multi-view renderings of objects under varying known illuminations. This architecture design enables to effectively decompose geometry and appearance, resolve the ambiguity between material and lighting, and capture the multi-modal distribution of shadows and specularity in the relit appearance. We show our sparse-view feed-forward RelitLRM offers competitive relighting results to state-of-the-art dense-view optimization-based baselines while being significantly faster. Our project page is available at: https://relit-lrm.github.io/.

Large language models (LLMs) and small language models (SLMs) are being adopted at remarkable speed, although their safety still remains a serious concern. With the advent of multilingual S/LLMs, the question now becomes a matter of scale: can we expand multilingual safety evaluations of these models with the same velocity at which they are deployed? To this end we introduce RTP-LX, a human-transcreated and human-annotated corpus of toxic prompts and outputs in 28 languages. RTP-LX follows participatory design practices, and a portion of the corpus is especially designed to detect culturally-specific toxic language. We evaluate seven S/LLMs on their ability to detect toxic content in a culturally-sensitive, multilingual scenario. We find that, although they typically score acceptably in terms of accuracy, they have low agreement with human judges when judging holistically the toxicity of a prompt, and have difficulty discerning harm in context-dependent scenarios, particularly with subtle-yet-harmful content (e.g. microagressions, bias). We release of this dataset to contribute to further reduce harmful uses of these models and improve their safe deployment.

The third ML4H symposium was held in person on December 10, 2023, in New Orleans, Louisiana, USA. The symposium included research roundtable sessions to foster discussions between participants and senior researchers on timely and relevant topics for the ML4H community. Encouraged by the successful virtual roundtables in the previous year, we organized eleven in-person roundtables and four virtual roundtables at ML4H 2022. The organization of the research roundtables at the conference involved 17 Senior Chairs and 19 Junior Chairs across 11 tables. Each roundtable session included invited senior chairs (with substantial experience in the field), junior chairs (responsible for facilitating the discussion), and attendees from diverse backgrounds with interest in the session's topic. Herein we detail the organization process and compile takeaways from these roundtable discussions, including recent advances, applications, and open challenges for each topic. We conclude with a summary and lessons learned across all roundtables. This document serves as a comprehensive review paper, summarizing the recent advancements in machine learning for healthcare as contributed by foremost researchers in the field.

In recent years, the potential applications of machine learning to Minimally Invasive Surgery (MIS) have spurred interest in data sets that can be used to develop data-driven tools. This paper introduces a novel dataset recorded during ex vivo pseudo-cholecystectomy procedures on pig livers, utilizing the da Vinci Research Kit (dVRK). Unlike current datasets, ours bridges a critical gap by offering not only full kinematic data but also capturing all pedal inputs used during the procedure and providing a time-stamped record of the endoscope's movements. Contributed by seven surgeons, this data set introduces a new dimension to surgical robotics research, allowing the creation of advanced models for automating console functionalities. Our work addresses the existing limitation of incomplete recordings and imprecise kinematic data, common in other datasets. By introducing two models, dedicated to predicting clutch usage and camera activation, we highlight the dataset's potential for advancing automation in surgical robotics. The comparison of methodologies and time windows provides insights into the models' boundaries and limitations.

This report introduces a new family of multimodal models, Gemini, that exhibit remarkable capabilities across image, audio, video, and text understanding. The Gemini family consists of Ultra, Pro, and Nano sizes, suitable for applications ranging from complex reasoning tasks to on-device memory-constrained use-cases. Evaluation on a broad range of benchmarks shows that our most-capable Gemini Ultra model advances the state of the art in 30 of 32 of these benchmarks - notably being the first model to achieve human-expert performance on the well-studied exam benchmark MMLU, and improving the state of the art in every one of the 20 multimodal benchmarks we examined. We believe that the new capabilities of Gemini models in cross-modal reasoning and language understanding will enable a wide variety of use cases and we discuss our approach toward deploying them responsibly to users.

We present Amazon Nova, a new generation of state-of-the-art foundation models that deliver frontier intelligence and industry-leading price performance. Amazon Nova Pro is a highly-capable multimodal model with the best combination of accuracy, speed, and cost for a wide range of tasks. Amazon Nova Lite is a low-cost multimodal model that is lightning fast for processing images, video, documents and text. Amazon Nova Micro is a text-only model that delivers our lowest-latency responses at very low cost. Amazon Nova Canvas is an image generation model that creates professional grade images with rich customization controls. Amazon Nova Reel is a video generation model offering high-quality outputs, customization, and motion control. Our models were built responsibly and with a commitment to customer trust, security, and reliability. We report benchmarking results for core capabilities, agentic performance, long context, functional adaptation, runtime performance, and human evaluation.