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Aug 12

Distilling Photon-Counting CT into Routine Chest CT through Clinically Validated Degradation Modeling

Photon-counting CT (PCCT) provides superior image quality with higher spatial resolution and lower noise compared to conventional energy-integrating CT (EICT), but its limited clinical availability restricts large-scale research and clinical deployment. To bridge this gap, we propose SUMI, a simulated degradation-to-enhancement method that learns to reverse realistic acquisition artifacts in low-quality EICT by leveraging high-quality PCCT as reference. Our central insight is to explicitly model realistic acquisition degradations, transforming PCCT into clinically plausible lower-quality counterparts and learning to invert this process. The simulated degradations were validated for clinical realism by board-certified radiologists, enabling faithful supervision without requiring paired acquisitions at scale. As outcomes of this technical contribution, we: (1) train a latent diffusion model on 1,046 PCCTs, using an autoencoder first pre-trained on both these PCCTs and 405,379 EICTs from 145 hospitals to extract general CT latent features that we release for reuse in other generative medical imaging tasks; (2) construct a large-scale dataset of over 17,316 publicly available EICTs enhanced to PCCT-like quality, with radiologist-validated voxel-wise annotations of airway trees, arteries, veins, lungs, and lobes; and (3) demonstrate substantial improvements: across external data, SUMI outperforms state-of-the-art image translation methods by 15% in SSIM and 20% in PSNR, improves radiologist-rated clinical utility in reader studies, and enhances downstream top-ranking lesion detection performance, increasing sensitivity by up to 15% and F1 score by up to 10%. Our results suggest that emerging imaging advances can be systematically distilled into routine EICT using limited high-quality scans as reference.

  • 13 authors
·
Apr 7

Global Inverse Design Across Multiple Photonic Structure Classes Using Generative Deep Learning

Understanding how nano- or micro-scale structures and material properties can be optimally configured to attain specific functionalities remains a fundamental challenge. Photonic metasurfaces, for instance, can be spectrally tuned through material choice and structural geometry to achieve unique optical responses. However, existing numerical design methods require prior identification of specific material-structure combinations, or device classes, as the starting point for optimization. As such, a unified solution that simultaneously optimizes across materials and geometries has yet to be realized. To overcome these challenges, we present a global deep learning-based inverse design framework, where a conditional deep convolutional generative adversarial network is trained on colored images encoded with a range of material and structural parameters, including refractive index, plasma frequency, and geometric design. We demonstrate that, in response to target absorption spectra, the network can identify an effective metasurface in terms of its class, materials properties, and overall shape. Furthermore, the model can arrive at multiple design variants with distinct materials and structures that present nearly identical absorption spectra. Our proposed framework is thus an important step towards global photonics and materials design strategies that can identify combinations of device categories, material properties, and geometric parameters which algorithmically deliver a sought functionality.

  • 9 authors
·
Dec 31, 2020

SP-TransientBench: A Real-Captured Single Photon Perception Benchmark

Single-photon LiDAR (SPL) based on single-photon avalanche diode (SPAD) sensing enables time-resolved photon measurements with extreme sensitivity, offering unique potential for active 3D perception in photon-starved scenarios.However, real-world single photon perception remains fundamentally challenging due to unique measurement noise and complex multi-return transient phenomena, which jointly complicate geometric reconstruction and semantic scene understanding. Despite growing interest in SPAD-based sensing, existing studies are largely limited to simulated data or small-scale controlled captures. As a result, systematic evaluation of real-world single photon perception across depth estimation, multi-view reconstruction, and 3D semantic understanding remains underexplored. To bridge this gap, we introduce SP-TransientBench (STB), a real-captured multi-task benchmark for single photon perception. SP-TransientBenc comprises 10 diverse scenes and 10,297 views captured using a solid-state single-photon LiDAR at 256times192 resolution. Each view provides full time-of-flight histograms with multi-return behavior,standardized metadata, and calibrated camera poses for multi-view evaluation. We further provide 13-class 3D semantic annotations for selected scenes. By providing dedicated data splits and evaluation protocols for each task, STB enables consistent and reproducible benchmarking of real-world single photon perception across multiple 3D vision problems. The dataset and code will be released upon acceptance.

  • 15 authors
·
Jun 15

Label-efficient Single Photon Images Classification via Active Learning

Single-photon LiDAR achieves high-precision 3D imaging in extreme environments through quantum-level photon detection technology. Current research primarily focuses on reconstructing 3D scenes from sparse photon events, whereas the semantic interpretation of single-photon images remains underexplored, due to high annotation costs and inefficient labeling strategies. This paper presents the first active learning framework for single-photon image classification. The core contribution is an imaging condition-aware sampling strategy that integrates synthetic augmentation to model variability across imaging conditions. By identifying samples where the model is both uncertain and sensitive to these conditions, the proposed method selectively annotates only the most informative examples. Experiments on both synthetic and real-world datasets show that our approach outperforms all baselines and achieves high classification accuracy with significantly fewer labeled samples. Specifically, our approach achieves 97% accuracy on synthetic single-photon data using only 1.5% labeled samples. On real-world data, we maintain 90.63% accuracy with just 8% labeled samples, which is 4.51% higher than the best-performing baseline. This illustrates that active learning enables the same level of classification performance on single-photon images as on classical images, opening doors to large-scale integration of single-photon data in real-world applications.

  • 8 authors
·
May 7, 2025

SPICE-HL3: Single-Photon, Inertial, and Stereo Camera dataset for Exploration of High-Latitude Lunar Landscapes

Exploring high-latitude lunar regions presents an extremely challenging visual environment for robots. The low sunlight elevation angle and minimal light scattering result in a visual field dominated by a high dynamic range featuring long, dynamic shadows. Reproducing these conditions on Earth requires sophisticated simulators and specialized facilities. We introduce a unique dataset recorded at the LunaLab from the SnT - University of Luxembourg, an indoor test facility designed to replicate the optical characteristics of multiple lunar latitudes. Our dataset includes images, inertial measurements, and wheel odometry data from robots navigating seven distinct trajectories under multiple illumination scenarios, simulating high-latitude lunar conditions from dawn to nighttime with and without the aid of headlights, resulting in 88 distinct sequences containing a total of 1.3M images. Data was captured using a stereo RGB-inertial sensor, a monocular monochrome camera, and for the first time, a novel single-photon avalanche diode (SPAD) camera. We recorded both static and dynamic image sequences, with robots navigating at slow (5 cm/s) and fast (50 cm/s) speeds. All data is calibrated, synchronized, and timestamped, providing a valuable resource for validating perception tasks from vision-based autonomous navigation to scientific imaging for future lunar missions targeting high-latitude regions or those intended for robots operating across perceptually degraded environments. The dataset and all supplementary material can be accessed from and found at https://github.com/spaceuma/spice-hl3.

UMASpaceRobotics UMA Space Robotics Lab
·
Jun 28, 2025

Establishing Baselines for Photonic Quantum Machine Learning: Insights from an Open, Collaborative Initiative

The Perceval Challenge is an open, reproducible benchmark designed to assess the potential of photonic quantum computing for machine learning. Focusing on a reduced and hardware-feasible version of the MNIST digit classification task or near-term photonic processors, it offers a concrete framework to evaluate how photonic quantum circuits learn and generalize from limited data. Conducted over more than three months, the challenge attracted 64 teams worldwide in its first phase. After an initial selection, 11 finalist teams were granted access to GPU resources for large-scale simulation and photonic hardware execution through cloud service. The results establish the first unified baseline of photonic machine-learning performance, revealing complementary strengths between variational, hardware-native, and hybrid approaches. This challenge also underscores the importance of open, reproducible experimentation and interdisciplinary collaboration, highlighting how shared benchmarks can accelerate progress in quantum-enhanced learning. All implementations are publicly available in a single shared repository (https://github.com/Quandela/HybridAIQuantum-Challenge), supporting transparent benchmarking and cumulative research. Beyond this specific task, the Perceval Challenge illustrates how systematic, collaborative experimentation can map the current landscape of photonic quantum machine learning and pave the way toward hybrid, quantum-augmented AI workflows.

  • 31 authors
·
Oct 29, 2025

From Pixels to PCells: A Neurosymbolic Approach to Photonic Component Creation

We present PixCell, a neurosymbolic system in which multimodal agents convert a visually presented photonic component into a parametric program over a small domain-specific language (DSL) of geometric primitives. A system enabling deterministic visual verification renders evaluation asymmetrically cheaper than the generation attempt. While models using multi-seed sampling and iterative revision reach a mean best-turn IoU of only 0.416, multimodal agents through PixCell's interface and verifier consistently exceed 0.9 mean IoU, with scores reaching 0.974 and 0.955 across eight component targets while also satisfying source contracts. These results demonstrate that frontier multimodal agents can reliably understand and render executable parametric representations from visual targets. Using these live parameters, cross-stack studies on an interferometer reconstruct primitive programs that satisfy an 8.0 nm free spectral range target and the original footprint constraint on modeled 220-nm SOI, 400-nm SiN, and 400-nm TFLN stacks. PixCell further carries a paper-derived splitter from visual reconstruction through SOI full-wave simulation, producing symmetric propagation and balanced outputs. Finally, the same executable verifier supplies a training reward and dataset used to train a Qwen3.6-35B-A3B model with LoRA and GRPO without supervised demonstrations. On eight training-excluded paper figures, its mean champion IoU rises from 0.422 after eight initial attempts to 0.491 after three verifier-guided revision rounds. These results therefore establish a controlled framework for measuring, retargeting, and improving visual-to-parametric photonic component design.

  • 3 authors
·
Jul 28

The Radio--X-ray Correlation of High-Redshift AGN: A Numerical Study of Inverse-Compton Scattering of the CMB Photons in Relativistic Jets

Relativistic jets from active galactic nuclei are expected to exhibit strong redshift evolution in their radiative output due to the increasing energy density of the cosmic microwave background (CMB). We investigate the role of inverse Compton (IC) scattering of CMB photons in regulating the radio and X-ray emission from large-scale jets using three-dimensional relativistic magnetohydrodynamic simulations coupled with a hybrid Eulerian-Lagrangian particle framework. By keeping the jet dynamics and ambient medium properties fixed across redshifts, we are able to isolate the impact of the cosmological evolution of the CMB on the jet radiation. From our simulations, we construct synthetic spectral energy distributions and intensity maps considering synchrotron and IC/CMB losses along with particle acceleration from shocks. We are able to reproduce the weak redshift dependence of radio luminosity and the strong enhancement of X-ray emission toward high redshift that is observed in radio-loud quasars. At high redshift, the X-ray luminosity follows the expected (1+z)^4 scaling, confirming IC/CMB as the dominant mechanism driving the X-ray enhancement. The resulting X-ray-to-radio flux ratio increases systematically with redshift and is consistent with observational constraints. Finally, we show that slower jets exhibit a stronger redshift evolution of the X-ray enhancement than faster jets, highlighting the critical role of jet propagation length scales and particle energy evolution. The simulations also naturally reproduce the steepening of the radio spectral index with redshift - the α-z relation - thus providing a unified framework that allows to interpret the multiwavelength properties of high-redshift radio sources.

  • 8 authors
·
May 29