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May 27

PLA4D: Pixel-Level Alignments for Text-to-4D Gaussian Splatting

As text-conditioned diffusion models (DMs) achieve breakthroughs in image, video, and 3D generation, the research community's focus has shifted to the more challenging task of text-to-4D synthesis, which introduces a temporal dimension to generate dynamic 3D objects. In this context, we identify Score Distillation Sampling (SDS), a widely used technique for text-to-3D synthesis, as a significant hindrance to text-to-4D performance due to its Janus-faced and texture-unrealistic problems coupled with high computational costs. In this paper, we propose Pixel-Level Alignments for Text-to-4D Gaussian Splatting (PLA4D), a novel method that utilizes text-to-video frames as explicit pixel alignment targets to generate static 3D objects and inject motion into them. Specifically, we introduce Focal Alignment to calibrate camera poses for rendering and GS-Mesh Contrastive Learning to distill geometry priors from rendered image contrasts at the pixel level. Additionally, we develop Motion Alignment using a deformation network to drive changes in Gaussians and implement Reference Refinement for smooth 4D object surfaces. These techniques enable 4D Gaussian Splatting to align geometry, texture, and motion with generated videos at the pixel level. Compared to previous methods, PLA4D produces synthesized outputs with better texture details in less time and effectively mitigates the Janus-faced problem. PLA4D is fully implemented using open-source models, offering an accessible, user-friendly, and promising direction for 4D digital content creation. Our project page: https://github.com/MiaoQiaowei/PLA4D.github.io{https://github.com/MiaoQiaowei/PLA4D.github.io}.

  • 3 authors
·
May 30, 2024

MolReFlect: Towards In-Context Fine-grained Alignments between Molecules and Texts

Molecule discovery is a pivotal research field, impacting everything from the medicines we take to the materials we use. Recently, Large Language Models (LLMs) have been widely adopted in molecule understanding and generation, yet the alignments between molecules and their corresponding captions remain a significant challenge. Previous endeavours often treat the molecule as a general SMILES string or molecular graph, neglecting the fine-grained alignments between the molecular sub-structures and the descriptive textual phrases, which are crucial for accurate and explainable predictions. In this case, we introduce MolReFlect, a novel teacher-student framework designed to contextually perform the molecule-caption alignments in a fine-grained way. Our approach initially leverages a larger teacher LLM to label the detailed alignments by directly extracting critical phrases from molecule captions or SMILES strings and implying them to corresponding sub-structures or characteristics. To refine these alignments, we propose In-Context Selective Reflection, which retrieves previous extraction results as context examples for teacher LLM to reflect and lets a smaller student LLM select from in-context reflection and previous extraction results. Finally, we enhance the learning process of the student LLM through Chain-of-Thought In-Context Molecule Tuning, integrating the fine-grained alignments and the reasoning processes within the Chain-of-Thought format. Our experimental results demonstrate that MolReFlect enables LLMs like Mistral-7B to significantly outperform the previous baselines, achieving SOTA performance on the ChEBI-20 dataset. This advancement not only enhances the generative capabilities of LLMs in the molecule-caption translation task, but also contributes to a more explainable framework.

  • 9 authors
·
Nov 21, 2024 2

HA-HI: Synergising fMRI and DTI through Hierarchical Alignments and Hierarchical Interactions for Mild Cognitive Impairment Diagnosis

Early diagnosis of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) utilizing multi-modal magnetic resonance imaging (MRI) is a pivotal area of research. While various regional and connectivity features from functional MRI (fMRI) and diffusion tensor imaging (DTI) have been employed to develop diagnosis models, most studies integrate these features without adequately addressing their alignment and interactions. This limits the potential to fully exploit the synergistic contributions of combined features and modalities. To solve this gap, our study introduces a novel Hierarchical Alignments and Hierarchical Interactions (HA-HI) method for MCI and SCD classification, leveraging the combined strengths of fMRI and DTI. HA-HI efficiently learns significant MCI- or SCD- related regional and connectivity features by aligning various feature types and hierarchically maximizing their interactions. Furthermore, to enhance the interpretability of our approach, we have developed the Synergistic Activation Map (SAM) technique, revealing the critical brain regions and connections that are indicative of MCI/SCD. Comprehensive evaluations on the ADNI dataset and our self-collected data demonstrate that HA-HI outperforms other existing methods in diagnosing MCI and SCD, making it a potentially vital and interpretable tool for early detection. The implementation of this method is publicly accessible at https://github.com/ICI-BCI/Dual-MRI-HA-HI.git.

  • 7 authors
·
Jan 2, 2024

Learning Trajectory-Word Alignments for Video-Language Tasks

In a video, an object usually appears as the trajectory, i.e., it spans over a few spatial but longer temporal patches, that contains abundant spatiotemporal contexts. However, modern Video-Language BERTs (VDL-BERTs) neglect this trajectory characteristic that they usually follow image-language BERTs (IL-BERTs) to deploy the patch-to-word (P2W) attention that may over-exploit trivial spatial contexts and neglect significant temporal contexts. To amend this, we propose a novel TW-BERT to learn Trajectory-Word alignment by a newly designed trajectory-to-word (T2W) attention for solving video-language tasks. Moreover, previous VDL-BERTs usually uniformly sample a few frames into the model while different trajectories have diverse graininess, i.e., some trajectories span longer frames and some span shorter, and using a few frames will lose certain useful temporal contexts. However, simply sampling more frames will also make pre-training infeasible due to the largely increased training burdens. To alleviate the problem, during the fine-tuning stage, we insert a novel Hierarchical Frame-Selector (HFS) module into the video encoder. HFS gradually selects the suitable frames conditioned on the text context for the later cross-modal encoder to learn better trajectory-word alignments. By the proposed T2W attention and HFS, our TW-BERT achieves SOTA performances on text-to-video retrieval tasks, and comparable performances on video question-answering tasks with some VDL-BERTs trained on much more data. The code will be available in the supplementary material.

  • 10 authors
·
Jan 5, 2023

Exploring Optimal Transport-Based Multi-Grained Alignments for Text-Molecule Retrieval

The field of bioinformatics has seen significant progress, making the cross-modal text-molecule retrieval task increasingly vital. This task focuses on accurately retrieving molecule structures based on textual descriptions, by effectively aligning textual descriptions and molecules to assist researchers in identifying suitable molecular candidates. However, many existing approaches overlook the details inherent in molecule sub-structures. In this work, we introduce the Optimal TRansport-based Multi-grained Alignments model (ORMA), a novel approach that facilitates multi-grained alignments between textual descriptions and molecules. Our model features a text encoder and a molecule encoder. The text encoder processes textual descriptions to generate both token-level and sentence-level representations, while molecules are modeled as hierarchical heterogeneous graphs, encompassing atom, motif, and molecule nodes to extract representations at these three levels. A key innovation in ORMA is the application of Optimal Transport (OT) to align tokens with motifs, creating multi-token representations that integrate multiple token alignments with their corresponding motifs. Additionally, we employ contrastive learning to refine cross-modal alignments at three distinct scales: token-atom, multitoken-motif, and sentence-molecule, ensuring that the similarities between correctly matched text-molecule pairs are maximized while those of unmatched pairs are minimized. To our knowledge, this is the first attempt to explore alignments at both the motif and multi-token levels. Experimental results on the ChEBI-20 and PCdes datasets demonstrate that ORMA significantly outperforms existing state-of-the-art (SOTA) models.

  • 7 authors
·
Nov 4, 2024

Iterative pseudo-forced alignment by acoustic CTC loss for self-supervised ASR domain adaptation

High-quality data labeling from specific domains is costly and human time-consuming. In this work, we propose a self-supervised domain adaptation method, based upon an iterative pseudo-forced alignment algorithm. The produced alignments are employed to customize an end-to-end Automatic Speech Recognition (ASR) and iteratively refined. The algorithm is fed with frame-wise character posteriors produced by a seed ASR, trained with out-of-domain data, and optimized throughout a Connectionist Temporal Classification (CTC) loss. The alignments are computed iteratively upon a corpus of broadcast TV. The process is repeated by reducing the quantity of text to be aligned or expanding the alignment window until finding the best possible audio-text alignment. The starting timestamps, or temporal anchors, are produced uniquely based on the confidence score of the last aligned utterance. This score is computed with the paths of the CTC-alignment matrix. With this methodology, no human-revised text references are required. Alignments from long audio files with low-quality transcriptions, like TV captions, are filtered out by confidence score and ready for further ASR adaptation. The obtained results, on both the Spanish RTVE2022 and CommonVoice databases, underpin the feasibility of using CTC-based systems to perform: highly accurate audio-text alignments, domain adaptation and semi-supervised training of end-to-end ASR.

  • 2 authors
·
Oct 27, 2022

Discriminately Treating Motion Components Evolves Joint Depth and Ego-Motion Learning

Unsupervised learning of depth and ego-motion, two fundamental 3D perception tasks, has made significant strides in recent years. However, most methods treat ego-motion as an auxiliary task, either mixing all motion types or excluding depth-independent rotational motions in supervision. Such designs limit the incorporation of strong geometric constraints, reducing reliability and robustness under diverse conditions. This study introduces a discriminative treatment of motion components, leveraging the geometric regularities of their respective rigid flows to benefit both depth and ego-motion estimation. Given consecutive video frames, network outputs first align the optical axes and imaging planes of the source and target cameras. Optical flows between frames are transformed through these alignments, and deviations are quantified to impose geometric constraints individually on each ego-motion component, enabling more targeted refinement. These alignments further reformulate the joint learning process into coaxial and coplanar forms, where depth and each translation component can be mutually derived through closed-form geometric relationships, introducing complementary constraints that improve depth robustness. DiMoDE, a general depth and ego-motion joint learning framework incorporating these designs, achieves state-of-the-art performance on multiple public datasets and a newly collected diverse real-world dataset, particularly under challenging conditions. Our source code will be publicly available at mias.group/DiMoDE upon publication.

  • 9 authors
·
Nov 3, 2025 1

Pairing interacting protein sequences using masked language modeling

Predicting which proteins interact together from amino-acid sequences is an important task. We develop a method to pair interacting protein sequences which leverages the power of protein language models trained on multiple sequence alignments, such as MSA Transformer and the EvoFormer module of AlphaFold. We formulate the problem of pairing interacting partners among the paralogs of two protein families in a differentiable way. We introduce a method called DiffPALM that solves it by exploiting the ability of MSA Transformer to fill in masked amino acids in multiple sequence alignments using the surrounding context. MSA Transformer encodes coevolution between functionally or structurally coupled amino acids. We show that it captures inter-chain coevolution, while it was trained on single-chain data, which means that it can be used out-of-distribution. Relying on MSA Transformer without fine-tuning, DiffPALM outperforms existing coevolution-based pairing methods on difficult benchmarks of shallow multiple sequence alignments extracted from ubiquitous prokaryotic protein datasets. It also outperforms an alternative method based on a state-of-the-art protein language model trained on single sequences. Paired alignments of interacting protein sequences are a crucial ingredient of supervised deep learning methods to predict the three-dimensional structure of protein complexes. DiffPALM substantially improves the structure prediction of some eukaryotic protein complexes by AlphaFold-Multimer, without significantly deteriorating any of those we tested. It also achieves competitive performance with using orthology-based pairing.

  • 3 authors
·
Aug 14, 2023

Emotional Conversation: Empowering Talking Faces with Cohesive Expression, Gaze and Pose Generation

Vivid talking face generation holds immense potential applications across diverse multimedia domains, such as film and game production. While existing methods accurately synchronize lip movements with input audio, they typically ignore crucial alignments between emotion and facial cues, which include expression, gaze, and head pose. These alignments are indispensable for synthesizing realistic videos. To address these issues, we propose a two-stage audio-driven talking face generation framework that employs 3D facial landmarks as intermediate variables. This framework achieves collaborative alignment of expression, gaze, and pose with emotions through self-supervised learning. Specifically, we decompose this task into two key steps, namely speech-to-landmarks synthesis and landmarks-to-face generation. The first step focuses on simultaneously synthesizing emotionally aligned facial cues, including normalized landmarks that represent expressions, gaze, and head pose. These cues are subsequently reassembled into relocated facial landmarks. In the second step, these relocated landmarks are mapped to latent key points using self-supervised learning and then input into a pretrained model to create high-quality face images. Extensive experiments on the MEAD dataset demonstrate that our model significantly advances the state-of-the-art performance in both visual quality and emotional alignment.

  • 2 authors
·
Jun 12, 2024

MultiPriv: Benchmarking Individual-Level Privacy Reasoning in Vision-Language Models

Modern Vision-Language Models (VLMs) demonstrate sophisticated reasoning, escalating privacy risks beyond simple attribute perception to individual-level linkage. Current privacy benchmarks are structurally insufficient for this new threat, as they primarily evaluate privacy perception while failing to address the more critical risk of privacy reasoning: a VLM's ability to infer and link distributed information to construct individual profiles. To address this critical gap, we propose MultiPriv, the first benchmark designed to systematically evaluate individual-level privacy reasoning in VLMs. We introduce the Privacy Perception and Reasoning (PPR) framework and construct a novel, bilingual multimodal dataset to support it. The dataset uniquely features a core component of synthetic individual profiles where identifiers (e.g., faces, names) are meticulously linked to sensitive attributes. This design enables nine challenging tasks evaluating the full PPR spectrum, from attribute detection to cross-image re-identification and chained inference. We conduct a large-scale evaluation of over 50 foundational and commercial VLMs. Our analysis reveals: (1) Many VLMs possess significant, unmeasured reasoning-based privacy risks. (2) Perception-level metrics are poor predictors of these reasoning risks, revealing a critical evaluation gap. (3) Existing safety alignments are inconsistent and ineffective against such reasoning-based attacks. MultiPriv exposes systemic vulnerabilities and provides the necessary framework for developing robust, privacy-preserving VLMs.

  • 8 authors
·
Nov 20, 2025

Graph Edit Distance with General Costs Using Neural Set Divergence

Graph Edit Distance (GED) measures the (dis-)similarity between two given graphs, in terms of the minimum-cost edit sequence that transforms one graph to the other. However, the exact computation of GED is NP-Hard, which has recently motivated the design of neural methods for GED estimation. However, they do not explicitly account for edit operations with different costs. In response, we propose GRAPHEDX, a neural GED estimator that can work with general costs specified for the four edit operations, viz., edge deletion, edge addition, node deletion and node addition. We first present GED as a quadratic assignment problem (QAP) that incorporates these four costs. Then, we represent each graph as a set of node and edge embeddings and use them to design a family of neural set divergence surrogates. We replace the QAP terms corresponding to each operation with their surrogates. Computing such neural set divergence require aligning nodes and edges of the two graphs. We learn these alignments using a Gumbel-Sinkhorn permutation generator, additionally ensuring that the node and edge alignments are consistent with each other. Moreover, these alignments are cognizant of both the presence and absence of edges between node-pairs. Experiments on several datasets, under a variety of edit cost settings, show that GRAPHEDX consistently outperforms state-of-the-art methods and heuristics in terms of prediction error.

  • 5 authors
·
Sep 26, 2024

Fine-Tuned Large Language Model for Visualization System: A Study on Self-Regulated Learning in Education

Large Language Models (LLMs) have shown great potential in intelligent visualization systems, especially for domain-specific applications. Integrating LLMs into visualization systems presents challenges, and we categorize these challenges into three alignments: domain problems with LLMs, visualization with LLMs, and interaction with LLMs. To achieve these alignments, we propose a framework and outline a workflow to guide the application of fine-tuned LLMs to enhance visual interactions for domain-specific tasks. These alignment challenges are critical in education because of the need for an intelligent visualization system to support beginners' self-regulated learning. Therefore, we apply the framework to education and introduce Tailor-Mind, an interactive visualization system designed to facilitate self-regulated learning for artificial intelligence beginners. Drawing on insights from a preliminary study, we identify self-regulated learning tasks and fine-tuning objectives to guide visualization design and tuning data construction. Our focus on aligning visualization with fine-tuned LLM makes Tailor-Mind more like a personalized tutor. Tailor-Mind also supports interactive recommendations to help beginners better achieve their learning goals. Model performance evaluations and user studies confirm that Tailor-Mind improves the self-regulated learning experience, effectively validating the proposed framework.

  • 10 authors
·
Jul 30, 2024

SERV-CT: A disparity dataset from CT for validation of endoscopic 3D reconstruction

In computer vision, reference datasets have been highly successful in promoting algorithmic development in stereo reconstruction. Surgical scenes gives rise to specific problems, including the lack of clear corner features, highly specular surfaces and the presence of blood and smoke. Publicly available datasets have been produced using CT and either phantom images or biological tissue samples covering a relatively small region of the endoscope field-of-view. We present a stereo-endoscopic reconstruction validation dataset based on CT (SERV-CT). Two {\it ex vivo} small porcine full torso cadavers were placed within the view of the endoscope with both the endoscope and target anatomy visible in the CT scan. Orientation of the endoscope was manually aligned to the stereoscopic view. Reference disparities and occlusions were calculated for 8 stereo pairs from each sample. For the second sample an RGB surface was acquired to aid alignment of smooth, featureless surfaces. Repeated manual alignments showed an RMS disparity accuracy of ~2 pixels and a depth accuracy of ~2mm. The reference dataset includes endoscope image pairs with corresponding calibration, disparities, depths and occlusions covering the majority of the endoscopic image and a range of tissue types. Smooth specular surfaces and images with significant variation of depth are included. We assessed the performance of various stereo algorithms from online available repositories. There is a significant variation between algorithms, highlighting some of the challenges of surgical endoscopic images. The SERV-CT dataset provides an easy to use stereoscopic validation for surgical applications with smooth reference disparities and depths with coverage over the majority of the endoscopic images. This complements existing resources well and we hope will aid the development of surgical endoscopic anatomical reconstruction algorithms.

  • 5 authors
·
Dec 21, 2020

ProteinNet: a standardized data set for machine learning of protein structure

Rapid progress in deep learning has spurred its application to bioinformatics problems including protein structure prediction and design. In classic machine learning problems like computer vision, progress has been driven by standardized data sets that facilitate fair assessment of new methods and lower the barrier to entry for non-domain experts. While data sets of protein sequence and structure exist, they lack certain components critical for machine learning, including high-quality multiple sequence alignments and insulated training / validation splits that account for deep but only weakly detectable homology across protein space. We have created the ProteinNet series of data sets to provide a standardized mechanism for training and assessing data-driven models of protein sequence-structure relationships. ProteinNet integrates sequence, structure, and evolutionary information in programmatically accessible file formats tailored for machine learning frameworks. Multiple sequence alignments of all structurally characterized proteins were created using substantial high-performance computing resources. Standardized data splits were also generated to emulate the difficulty of past CASP (Critical Assessment of protein Structure Prediction) experiments by resetting protein sequence and structure space to the historical states that preceded six prior CASPs. Utilizing sensitive evolution-based distance metrics to segregate distantly related proteins, we have additionally created validation sets distinct from the official CASP sets that faithfully mimic their difficulty. ProteinNet thus represents a comprehensive and accessible resource for training and assessing machine-learned models of protein structure.

  • 1 authors
·
Jan 31, 2019

LEMAS: Large A 150K-Hour Large-scale Extensible Multilingual Audio Suite with Generative Speech Models

We present the LEMAS-Dataset, which, to our knowledge, is currently the largest open-source multilingual speech corpus with word-level timestamps. Covering over 150,000 hours across 10 major languages, LEMAS-Dataset is constructed via a efficient data processing pipeline that ensures high-quality data and annotations. To validate the effectiveness of LEMAS-Dataset across diverse generative paradigms, we train two benchmark models with distinct architectures and task specializations on this dataset. LEMAS-TTS, built upon a non-autoregressive flow-matching framework, leverages the dataset's massive scale and linguistic diversity to achieve robust zero-shot multilingual synthesis. Our proposed accent-adversarial training and CTC loss mitigate cross-lingual accent issues, enhancing synthesis stability. Complementarily, LEMAS-Edit employs an autoregressive decoder-only architecture that formulates speech editing as a masked token infilling task. By exploiting precise word-level alignments to construct training masks and adopting adaptive decoding strategies, it achieves seamless, smooth-boundary speech editing with natural transitions. Experimental results demonstrate that models trained on LEMAS-Dataset deliver high-quality synthesis and editing performance, confirming the dataset's quality. We envision that this richly timestamp-annotated, fine-grained multilingual corpus will drive future advances in prompt-based speech generation systems.

LEMAS-Project LEMAS
·
Jan 3 2

A Contrastive Learning-Guided Confident Meta-learning for Zero Shot Anomaly Detection

Industrial and medical anomaly detection faces critical challenges from data scarcity and prohibitive annotation costs, particularly in evolving manufacturing and healthcare settings. To address this, we propose CoZAD, a novel zero-shot anomaly detection framework that integrates soft confident learning with meta-learning and contrastive feature representation. Unlike traditional confident learning that discards uncertain samples, our method assigns confidence-based weights to all training data, preserving boundary information while emphasizing prototypical normal patterns. The framework quantifies data uncertainty through IQR-based thresholding and model uncertainty via covariance based regularization within a Model-Agnostic Meta-Learning. Contrastive learning creates discriminative feature spaces where normal patterns form compact clusters, enabling rapid domain adaptation. Comprehensive evaluation across 10 datasets spanning industrial and medical domains demonstrates state-of-the-art performance, outperforming existing methods on 6 out of 7 industrial benchmarks with notable improvements on texture-rich datasets (99.2% I-AUROC on DTD-Synthetic, 97.2% on BTAD) and pixellevel localization (96.3% P-AUROC on MVTec-AD). The framework eliminates dependence on vision-language alignments or model ensembles, making it valuable for resourceconstrained environments requiring rapid deployment.

  • 4 authors
·
Aug 25, 2025

Personality Alignment of Large Language Models

Current methods for aligning large language models (LLMs) typically aim to reflect general human values and behaviors, but they often fail to capture the unique characteristics and preferences of individual users. To address this gap, we introduce the concept of Personality Alignment. This approach tailors LLMs' responses and decisions to match the specific preferences of individual users or closely related groups. Inspired by psychometrics, we created the Personality Alignment with Personality Inventories (PAPI) dataset, which includes data from 300,000 real subjects, each providing behavioral preferences based on the Big Five Personality Factors. This dataset allows us to quantitatively evaluate the extent to which LLMs can align with each subject's behavioral patterns. Recognizing the challenges of personality alignments: such as limited personal data, diverse preferences, and scalability requirements: we developed an activation intervention optimization method. This method enhances LLMs' ability to efficiently align with individual behavioral preferences using minimal data and computational resources. Remarkably, our method, PAS, achieves superior performance while requiring only 1/5 of the optimization time compared to DPO, offering practical value for personality alignment. Our work paves the way for future AI systems to make decisions and reason in truly personality ways, enhancing the relevance and meaning of AI interactions for each user and advancing human-centered artificial intelligence.The code has released in https://github.com/zhu-minjun/PAlign.

  • 3 authors
·
Aug 21, 2024

MeDSLIP: Medical Dual-Stream Language-Image Pre-training for Fine-grained Alignment

Vision-language pre-training (VLP) models have shown significant advancements in the medical domain. Yet, most VLP models align raw reports to images at a very coarse level, without modeling fine-grained relationships between anatomical and pathological concepts outlined in reports and the corresponding semantic counterparts in images. To address this problem, we propose a Medical Dual-Stream Language-Image Pre-training (MeDSLIP) framework. Specifically, MeDSLIP establishes vision-language fine-grained alignments via disentangling visual and textual representations into anatomy-relevant and pathology-relevant streams. Moreover, a novel vision-language Prototypical Contr-astive Learning (ProtoCL) method is adopted in MeDSLIP to enhance the alignment within the anatomical and pathological streams. MeDSLIP further employs cross-stream Intra-image Contrastive Learning (ICL) to ensure the consistent coexistence of paired anatomical and pathological concepts within the same image. Such a cross-stream regularization encourages the model to exploit the synchrony between two streams for a more comprehensive representation learning. MeDSLIP is evaluated under zero-shot and supervised fine-tuning settings on three public datasets: NIH CXR14, RSNA Pneumonia, and SIIM-ACR Pneumothorax. Under these settings, MeDSLIP outperforms six leading CNN-based models on classification, grounding, and segmentation tasks.

  • 9 authors
·
Mar 15, 2024

BrainSCUBA: Fine-Grained Natural Language Captions of Visual Cortex Selectivity

Understanding the functional organization of higher visual cortex is a central focus in neuroscience. Past studies have primarily mapped the visual and semantic selectivity of neural populations using hand-selected stimuli, which may potentially bias results towards pre-existing hypotheses of visual cortex functionality. Moving beyond conventional approaches, we introduce a data-driven method that generates natural language descriptions for images predicted to maximally activate individual voxels of interest. Our method -- Semantic Captioning Using Brain Alignments ("BrainSCUBA") -- builds upon the rich embedding space learned by a contrastive vision-language model and utilizes a pre-trained large language model to generate interpretable captions. We validate our method through fine-grained voxel-level captioning across higher-order visual regions. We further perform text-conditioned image synthesis with the captions, and show that our images are semantically coherent and yield high predicted activations. Finally, to demonstrate how our method enables scientific discovery, we perform exploratory investigations on the distribution of "person" representations in the brain, and discover fine-grained semantic selectivity in body-selective areas. Unlike earlier studies that decode text, our method derives voxel-wise captions of semantic selectivity. Our results show that BrainSCUBA is a promising means for understanding functional preferences in the brain, and provides motivation for further hypothesis-driven investigation of visual cortex.

  • 4 authors
·
Oct 6, 2023

Align With Purpose: Optimize Desired Properties in CTC Models with a General Plug-and-Play Framework

Connectionist Temporal Classification (CTC) is a widely used criterion for training supervised sequence-to-sequence (seq2seq) models. It enables learning the relations between input and output sequences, termed alignments, by marginalizing over perfect alignments (that yield the ground truth), at the expense of imperfect alignments. This binary differentiation of perfect and imperfect alignments falls short of capturing other essential alignment properties that hold significance in other real-world applications. Here we propose Align With Purpose, a general Plug-and-Play framework for enhancing a desired property in models trained with the CTC criterion. We do that by complementing the CTC with an additional loss term that prioritizes alignments according to a desired property. Our method does not require any intervention in the CTC loss function, enables easy optimization of a variety of properties, and allows differentiation between both perfect and imperfect alignments. We apply our framework in the domain of Automatic Speech Recognition (ASR) and show its generality in terms of property selection, architectural choice, and scale of training dataset (up to 280,000 hours). To demonstrate the effectiveness of our framework, we apply it to two unrelated properties: emission time and word error rate (WER). For the former, we report an improvement of up to 570ms in latency optimization with a minor reduction in WER, and for the latter, we report a relative improvement of 4.5% WER over the baseline models. To the best of our knowledge, these applications have never been demonstrated to work on a scale of data as large as ours. Notably, our method can be implemented using only a few lines of code, and can be extended to other alignment-free loss functions and to domains other than ASR.

  • 11 authors
·
Jul 4, 2023

Plug-and-Play Regulators for Image-Text Matching

Exploiting fine-grained correspondence and visual-semantic alignments has shown great potential in image-text matching. Generally, recent approaches first employ a cross-modal attention unit to capture latent region-word interactions, and then integrate all the alignments to obtain the final similarity. However, most of them adopt one-time forward association or aggregation strategies with complex architectures or additional information, while ignoring the regulation ability of network feedback. In this paper, we develop two simple but quite effective regulators which efficiently encode the message output to automatically contextualize and aggregate cross-modal representations. Specifically, we propose (i) a Recurrent Correspondence Regulator (RCR) which facilitates the cross-modal attention unit progressively with adaptive attention factors to capture more flexible correspondence, and (ii) a Recurrent Aggregation Regulator (RAR) which adjusts the aggregation weights repeatedly to increasingly emphasize important alignments and dilute unimportant ones. Besides, it is interesting that RCR and RAR are plug-and-play: both of them can be incorporated into many frameworks based on cross-modal interaction to obtain significant benefits, and their cooperation achieves further improvements. Extensive experiments on MSCOCO and Flickr30K datasets validate that they can bring an impressive and consistent R@1 gain on multiple models, confirming the general effectiveness and generalization ability of the proposed methods. Code and pre-trained models are available at: https://github.com/Paranioar/RCAR.

  • 5 authors
·
Mar 23, 2023

Plan-X: Instruct Video Generation via Semantic Planning

Diffusion Transformers have demonstrated remarkable capabilities in visual synthesis, yet they often struggle with high-level semantic reasoning and long-horizon planning. This limitation frequently leads to visual hallucinations and mis-alignments with user instructions, especially in scenarios involving complex scene understanding, human-object interactions, multi-stage actions, and in-context motion reasoning. To address these challenges, we propose Plan-X, a framework that explicitly enforces high-level semantic planning to instruct video generation process. At its core lies a Semantic Planner, a learnable multimodal language model that reasons over the user's intent from both text prompts and visual context, and autoregressively generates a sequence of text-grounded spatio-temporal semantic tokens. These semantic tokens, complementary to high-level text prompt guidance, serve as structured "semantic sketches" over time for the video diffusion model, which has its strength at synthesizing high-fidelity visual details. Plan-X effectively integrates the strength of language models in multimodal in-context reasoning and planning, together with the strength of diffusion models in photorealistic video synthesis. Extensive experiments demonstrate that our framework substantially reduces visual hallucinations and enables fine-grained, instruction-aligned video generation consistent with multimodal context.

  • 10 authors
·
Nov 22, 2025 2

GPT4RoI: Instruction Tuning Large Language Model on Region-of-Interest

Instruction tuning large language model (LLM) on image-text pairs has achieved unprecedented vision-language multimodal abilities. However, their vision-language alignments are only built on image-level, the lack of region-level alignment limits their advancements to fine-grained multimodal understanding. In this paper, we propose instruction tuning on region-of-interest. The key design is to reformulate the bounding box as the format of spatial instruction. The interleaved sequences of visual features extracted by the spatial instruction and the language embedding are input to LLM, and trained on the transformed region-text data in instruction tuning format. Our region-level vision-language model, termed as GPT4RoI, brings brand new conversational and interactive experience beyond image-level understanding. (1) Controllability: Users can interact with our model by both language and spatial instructions to flexibly adjust the detail level of the question. (2) Capacities: Our model supports not only single-region spatial instruction but also multi-region. This unlocks more region-level multimodal capacities such as detailed region caption and complex region reasoning. (3) Composition: Any off-the-shelf object detector can be a spatial instruction provider so as to mine informative object attributes from our model, like color, shape, material, action, relation to other objects, etc. The code, data, and demo can be found at https://github.com/jshilong/GPT4RoI.

  • 8 authors
·
Jul 7, 2023

LychSim: A Controllable and Interactive Simulation Framework for Vision Research

While self-supervised pretraining has reduced vision systems' reliance on synthetic data, simulation remains an indispensable tool for closed-loop optimization and rigorous out-of-distribution (OOD) evaluation. However, modern simulation platforms often present steep technical barriers, requiring extensive expertise in computer graphics and game development. In this work, we present LychSim, a highly controllable and interactive simulation framework built upon Unreal Engine 5 to bridge this gap. LychSim is built around three key designs: (1) a streamlined Python API that abstracts away underlying engine complexities; (2) a procedural data pipeline capable of generating diverse, high-fidelity environments with varying out-of-distribution (OOD) visual challenges, paired with rich 2D and 3D ground truths; and (3) a native integration of the Model Context Protocol (MCP) that transforms the simulator into a dynamic, closed-loop playground for reasoning agentic LLMs. We further annotate scene-level procedural rules and object-level pose alignments to enable semantically aligned 3D ground truths and automated scene modification. We demonstrate LychSim's capability across multiple downstream applications, including serving as a synthetic data engine, powering reinforcement learning-based adversarial examiners, and facilitating interactive, language-driven scene layout generation. To benefit the broader vision community, LychSim will be made publicly available, including full source code and various data annotations.

The Role of Mixed-Language Documents for Multilingual Large Language Model Pretraining

Multilingual large language models achieve impressive cross-lingual performance despite largely monolingual pretraining. While bilingual data in pretraining corpora is widely believed to enable these abilities, details of its contributions remain unclear. We investigate this question by pretraining models from scratch under controlled conditions, comparing the standard web corpus with a monolingual-only version that removes all multilingual documents. Despite constituting only 2% of the corpus, removing bilingual data causes translation performance to drop 56% in BLEU, while behaviour on cross-lingual QA and general reasoning tasks remains stable, with training curves largely overlapping the baseline. To understand this asymmetry, we categorize bilingual data into parallel (14%), code-switching (72%), and miscellaneous documents (14%) based on the semantic relevance of content in different languages. We then conduct granular ablations by reintroducing parallel or code-switching data into the monolingual-only corpus. Our experiments reveal that parallel data almost fully restores translation performance (91% of the unfiltered baseline), whereas code-switching contributes minimally. Other cross-lingual tasks remain largely unaffected by either type. These findings reveal that translation critically depends on systematic token-level alignments from parallel data, whereas cross-lingual understanding and reasoning appear to be achievable even without bilingual data.

  • 7 authors
·
Jan 22

Iteratively Refined Early Interaction Alignment for Subgraph Matching based Graph Retrieval

Graph retrieval based on subgraph isomorphism has several real-world applications such as scene graph retrieval, molecular fingerprint detection and circuit design. Roy et al. [35] proposed IsoNet, a late interaction model for subgraph matching, which first computes the node and edge embeddings of each graph independently of paired graph and then computes a trainable alignment map. Here, we present IsoNet++, an early interaction graph neural network (GNN), based on several technical innovations. First, we compute embeddings of all nodes by passing messages within and across the two input graphs, guided by an injective alignment between their nodes. Second, we update this alignment in a lazy fashion over multiple rounds. Within each round, we run a layerwise GNN from scratch, based on the current state of the alignment. After the completion of one round of GNN, we use the last-layer embeddings to update the alignments, and proceed to the next round. Third, IsoNet++ incorporates a novel notion of node-pair partner interaction. Traditional early interaction computes attention between a node and its potential partners in the other graph, the attention then controlling messages passed across graphs. In contrast, we consider node pairs (not single nodes) as potential partners. Existence of an edge between the nodes in one graph and non-existence in the other provide vital signals for refining the alignment. Our experiments on several datasets show that the alignments get progressively refined with successive rounds, resulting in significantly better retrieval performance than existing methods. We demonstrate that all three innovations contribute to the enhanced accuracy. Our code and datasets are publicly available at https://github.com/structlearning/isonetpp.

  • 5 authors
·
Oct 26, 2025

LCFO: Long Context and Long Form Output Dataset and Benchmarking

This paper presents the Long Context and Form Output (LCFO) benchmark, a novel evaluation framework for assessing gradual summarization and summary expansion capabilities across diverse domains. LCFO consists of long input documents (5k words average length), each of which comes with three summaries of different lengths (20%, 10%, and 5% of the input text), as well as approximately 15 questions and answers (QA) related to the input content. Notably, LCFO also provides alignments between specific QA pairs and corresponding summaries in 7 domains. The primary motivation behind providing summaries of different lengths is to establish a controllable framework for generating long texts from shorter inputs, i.e. summary expansion. To establish an evaluation metric framework for summarization and summary expansion, we provide human evaluation scores for human-generated outputs, as well as results from various state-of-the-art large language models (LLMs). GPT-4o-mini achieves best human scores among automatic systems in both summarization and summary expansion tasks (~ +10% and +20%, respectively). It even surpasses human output quality in the case of short summaries (~ +7%). Overall automatic metrics achieve low correlations with human evaluation scores (~ 0.4) but moderate correlation on specific evaluation aspects such as fluency and attribution (~ 0.6). The LCFO benchmark offers a standardized platform for evaluating summarization and summary expansion performance, as well as corresponding automatic metrics, thereby providing an important evaluation framework to advance generative AI.

  • 13 authors
·
Dec 11, 2024

LLM-Align: Utilizing Large Language Models for Entity Alignment in Knowledge Graphs

Entity Alignment (EA) seeks to identify and match corresponding entities across different Knowledge Graphs (KGs), playing a crucial role in knowledge fusion and integration. Embedding-based entity alignment (EA) has recently gained considerable attention, resulting in the emergence of many innovative approaches. Initially, these approaches concentrated on learning entity embeddings based on the structural features of knowledge graphs (KGs) as defined by relation triples. Subsequent methods have integrated entities' names and attributes as supplementary information to improve the embeddings used for EA. However, existing methods lack a deep semantic understanding of entity attributes and relations. In this paper, we propose a Large Language Model (LLM) based Entity Alignment method, LLM-Align, which explores the instruction-following and zero-shot capabilities of Large Language Models to infer alignments of entities. LLM-Align uses heuristic methods to select important attributes and relations of entities, and then feeds the selected triples of entities to an LLM to infer the alignment results. To guarantee the quality of alignment results, we design a multi-round voting mechanism to mitigate the hallucination and positional bias issues that occur with LLMs. Experiments on three EA datasets, demonstrating that our approach achieves state-of-the-art performance compared to existing EA methods.

  • 3 authors
·
Dec 5, 2024

Backdoor Activation Attack: Attack Large Language Models using Activation Steering for Safety-Alignment

To ensure AI safety, instruction-tuned Large Language Models (LLMs) are specifically trained to ensure alignment, which refers to making models behave in accordance with human intentions. While these models have demonstrated commendable results on various safety benchmarks, the vulnerability of their safety alignment has not been extensively studied. This is particularly troubling given the potential harm that LLMs can inflict. Existing attack methods on LLMs often rely on poisoned training data or the injection of malicious prompts. These approaches compromise the stealthiness and generalizability of the attacks, making them susceptible to detection. Additionally, these models often demand substantial computational resources for implementation, making them less practical for real-world applications. Inspired by recent success in modifying model behavior through steering vectors without the need for optimization, and drawing on its effectiveness in red-teaming LLMs, we conducted experiments employing activation steering to target four key aspects of LLMs: truthfulness, toxicity, bias, and harmfulness - across a varied set of attack settings. To establish a universal attack strategy applicable to diverse target alignments without depending on manual analysis, we automatically select the intervention layer based on contrastive layer search. Our experiment results show that activation attacks are highly effective and add little or no overhead to attack efficiency. Additionally, we discuss potential countermeasures against such activation attacks. Our code and data are available at https://github.com/wang2226/Backdoor-Activation-Attack Warning: this paper contains content that can be offensive or upsetting.

  • 2 authors
·
Nov 15, 2023

LoFT: Local Proxy Fine-tuning For Improving Transferability Of Adversarial Attacks Against Large Language Model

It has been shown that Large Language Model (LLM) alignments can be circumvented by appending specially crafted attack suffixes with harmful queries to elicit harmful responses. To conduct attacks against private target models whose characterization is unknown, public models can be used as proxies to fashion the attack, with successful attacks being transferred from public proxies to private target models. The success rate of attack depends on how closely the proxy model approximates the private model. We hypothesize that for attacks to be transferrable, it is sufficient if the proxy can approximate the target model in the neighborhood of the harmful query. Therefore, in this paper, we propose Local Fine-Tuning (LoFT), i.e., fine-tuning proxy models on similar queries that lie in the lexico-semantic neighborhood of harmful queries to decrease the divergence between the proxy and target models. First, we demonstrate three approaches to prompt private target models to obtain similar queries given harmful queries. Next, we obtain data for local fine-tuning by eliciting responses from target models for the generated similar queries. Then, we optimize attack suffixes to generate attack prompts and evaluate the impact of our local fine-tuning on the attack's success rate. Experiments show that local fine-tuning of proxy models improves attack transferability and increases attack success rate by 39%, 7%, and 0.5% (absolute) on target models ChatGPT, GPT-4, and Claude respectively.

  • 13 authors
·
Oct 2, 2023

Tranception: protein fitness prediction with autoregressive transformers and inference-time retrieval

The ability to accurately model the fitness landscape of protein sequences is critical to a wide range of applications, from quantifying the effects of human variants on disease likelihood, to predicting immune-escape mutations in viruses and designing novel biotherapeutic proteins. Deep generative models of protein sequences trained on multiple sequence alignments have been the most successful approaches so far to address these tasks. The performance of these methods is however contingent on the availability of sufficiently deep and diverse alignments for reliable training. Their potential scope is thus limited by the fact many protein families are hard, if not impossible, to align. Large language models trained on massive quantities of non-aligned protein sequences from diverse families address these problems and show potential to eventually bridge the performance gap. We introduce Tranception, a novel transformer architecture leveraging autoregressive predictions and retrieval of homologous sequences at inference to achieve state-of-the-art fitness prediction performance. Given its markedly higher performance on multiple mutants, robustness to shallow alignments and ability to score indels, our approach offers significant gain of scope over existing approaches. To enable more rigorous model testing across a broader range of protein families, we develop ProteinGym -- an extensive set of multiplexed assays of variant effects, substantially increasing both the number and diversity of assays compared to existing benchmarks.

  • 7 authors
·
May 27, 2022

FastEmit: Low-latency Streaming ASR with Sequence-level Emission Regularization

Streaming automatic speech recognition (ASR) aims to emit each hypothesized word as quickly and accurately as possible. However, emitting fast without degrading quality, as measured by word error rate (WER), is highly challenging. Existing approaches including Early and Late Penalties and Constrained Alignments penalize emission delay by manipulating per-token or per-frame probability prediction in sequence transducer models. While being successful in reducing delay, these approaches suffer from significant accuracy regression and also require additional word alignment information from an existing model. In this work, we propose a sequence-level emission regularization method, named FastEmit, that applies latency regularization directly on per-sequence probability in training transducer models, and does not require any alignment. We demonstrate that FastEmit is more suitable to the sequence-level optimization of transducer models for streaming ASR by applying it on various end-to-end streaming ASR networks including RNN-Transducer, Transformer-Transducer, ConvNet-Transducer and Conformer-Transducer. We achieve 150-300 ms latency reduction with significantly better accuracy over previous techniques on a Voice Search test set. FastEmit also improves streaming ASR accuracy from 4.4%/8.9% to 3.1%/7.5% WER, meanwhile reduces 90th percentile latency from 210 ms to only 30 ms on LibriSpeech.

  • 11 authors
·
Feb 2, 2021

FastSpeech: Fast, Robust and Controllable Text to Speech

Neural network based end-to-end text to speech (TTS) has significantly improved the quality of synthesized speech. Prominent methods (e.g., Tacotron 2) usually first generate mel-spectrogram from text, and then synthesize speech from the mel-spectrogram using vocoder such as WaveNet. Compared with traditional concatenative and statistical parametric approaches, neural network based end-to-end models suffer from slow inference speed, and the synthesized speech is usually not robust (i.e., some words are skipped or repeated) and lack of controllability (voice speed or prosody control). In this work, we propose a novel feed-forward network based on Transformer to generate mel-spectrogram in parallel for TTS. Specifically, we extract attention alignments from an encoder-decoder based teacher model for phoneme duration prediction, which is used by a length regulator to expand the source phoneme sequence to match the length of the target mel-spectrogram sequence for parallel mel-spectrogram generation. Experiments on the LJSpeech dataset show that our parallel model matches autoregressive models in terms of speech quality, nearly eliminates the problem of word skipping and repeating in particularly hard cases, and can adjust voice speed smoothly. Most importantly, compared with autoregressive Transformer TTS, our model speeds up mel-spectrogram generation by 270x and the end-to-end speech synthesis by 38x. Therefore, we call our model FastSpeech.

  • 7 authors
·
May 22, 2019 1

Stream-Omni: Simultaneous Multimodal Interactions with Large Language-Vision-Speech Model

The emergence of GPT-4o-like large multimodal models (LMMs) has raised the exploration of integrating text, vision, and speech modalities to support more flexible multimodal interaction. Existing LMMs typically concatenate representation of modalities along the sequence dimension and feed them into a large language model (LLM) backbone. While sequence-dimension concatenation is straightforward for modality integration, it often relies heavily on large-scale data to learn modality alignments. In this paper, we aim to model the relationships between modalities more purposefully, thereby achieving more efficient and flexible modality alignments. To this end, we propose Stream-Omni, a large language-vision-speech model with efficient modality alignments, which can simultaneously support interactions under various modality combinations. Stream-Omni employs LLM as the backbone and aligns the vision and speech to the text based on their relationships. For vision that is semantically complementary to text, Stream-Omni uses sequence-dimension concatenation to achieve vision-text alignment. For speech that is semantically consistent with text, Stream-Omni introduces a CTC-based layer-dimension mapping to achieve speech-text alignment. In this way, Stream-Omni can achieve modality alignments with less data (especially speech), enabling the transfer of text capabilities to other modalities. Experiments on various benchmarks demonstrate that Stream-Omni achieves strong performance on visual understanding, speech interaction, and vision-grounded speech interaction tasks. Owing to the layer-dimensional mapping, Stream-Omni can simultaneously provide intermediate text outputs (such as ASR transcriptions and model responses) during speech interaction, offering users a comprehensive multimodal experience.

  • 5 authors
·
Jun 16, 2025 2

GTA1: GUI Test-time Scaling Agent

Graphical user interface (GUI) agents autonomously operate across platforms (e.g., Linux) to complete tasks by interacting with visual elements. Specifically, a user instruction is decomposed into a sequence of action proposals, each corresponding to an interaction with the GUI. After each action, the agent observes the updated GUI environment to plan the next step. However, two main challenges arise: i) resolving ambiguity in task planning (i.e., the action proposal sequence), where selecting an appropriate plan is non-trivial, as many valid ones may exist; ii) accurately grounding actions in complex and high-resolution interfaces, i.e., precisely interacting with visual targets. This paper investigates the two aforementioned challenges with our GUI Test-time Scaling Agent, namely GTA1. First, to select the most appropriate action proposal, we introduce a test-time scaling method. At each step, we sample multiple candidate action proposals and leverage a judge model to evaluate and select the most suitable one. It trades off computation for better decision quality by concurrent sampling, shortening task execution steps, and improving overall performance. Second, we propose a model that achieves improved accuracy when grounding the selected action proposal to its corresponding visual elements. Our key insight is that reinforcement learning (RL) facilitates visual grounding through inherent objective alignments, rewarding successful clicks on interface elements. Experimentally, our method establishes state-of-the-art performance across diverse benchmarks. For example, GTA1-7B achieves 50.1%, 92.4%, and 67.7% accuracies on Screenspot-Pro, Screenspot-V2, and OSWorld-G, respectively. When paired with a planner applying our test-time scaling strategy, it exhibits state-of-the-art agentic performance (e.g., 45.2% task success rate on OSWorld). We open-source our code and models here.

SeFi-IDE: Semantic-Fidelity Identity Embedding for Personalized Diffusion-Based Generation

Advanced diffusion-based Text-to-Image (T2I) models, such as the Stable Diffusion Model, have made significant progress in generating diverse and high-quality images using text prompts alone. However, T2I models are unable to accurately map identities (IDs) when non-famous users require personalized image generation. The main problem is that existing T2I models do not learn the ID-image alignments of new users. The previous methods either failed to accurately fit the face region or lost the interactive generative ability with other existing concepts in T2I models (i.e., unable to generate other concepts described in given prompts such as scenes, actions, and facial attributes). In this paper, we focus on accurate and semantic-fidelity ID embedding into the Stable Diffusion Model for personalized generation. We address this challenge from two perspectives: face-wise region fitting, and semantic-fidelity token optimization. Specifically, we first visualize the attention overfit problem, and propose a face-wise attention loss to fit the face region instead of the whole target image. This key trick significantly enhances the ID accuracy and interactive generative ability with other existing concepts. Then, we optimize one ID representation as multiple per-stage tokens where each token contains two disentangled features. This expansion of the textual conditioning space enhances semantic-fidelity control. Extensive experiments validate that our results exhibit superior ID accuracy and manipulation ability compared to previous methods.

  • 4 authors
·
Jan 31, 2024

SemanticCite: Citation Verification with AI-Powered Full-Text Analysis and Evidence-Based Reasoning

Effective scientific communication depends on accurate citations that validate sources and guide readers to supporting evidence. Yet academic literature faces mounting challenges: semantic citation errors that misrepresent sources, AI-generated hallucinated references, and traditional citation formats that point to entire papers without indicating which sections substantiate specific claims. We introduce SemanticCite, an AI-powered system that verifies citation accuracy through full-text source analysis while providing rich contextual information via detailed reasoning and relevant text snippets. Our approach combines multiple retrieval methods with a four-class classification system (Supported, Partially Supported, Unsupported, Uncertain) that captures nuanced claim-source relationships and enables appropriate remedial actions for different error types. Our experiments show that fine-tuned lightweight language models achieve performance comparable to large commercial systems with significantly lower computational requirements, making large-scale citation verification practically feasible. The system provides transparent, evidence-based explanations that support user understanding and trust. We contribute a comprehensive dataset of over 1,000 citations with detailed alignments, functional classifications, semantic annotations, and bibliometric metadata across eight disciplines, alongside fine-tuned models and the complete verification framework as open-source software. SemanticCite addresses critical challenges in research integrity through scalable citation verification, streamlined peer review, and quality control for AI-generated content, providing an open-source foundation for maintaining citation accuracy at scale.

  • 1 authors
·
Nov 20, 2025

Calibrated Multimodal Representation Learning with Missing Modalities

Multimodal representation learning harmonizes distinct modalities by aligning them into a unified latent space. Recent research generalizes traditional cross-modal alignment to produce enhanced multimodal synergy but requires all modalities to be present for a common instance, making it challenging to utilize prevalent datasets with missing modalities. We provide theoretical insights into this issue from an anchor shift perspective. Observed modalities are aligned with a local anchor that deviates from the optimal one when all modalities are present, resulting in an inevitable shift. To address this, we propose CalMRL for multimodal representation learning to calibrate incomplete alignments caused by missing modalities. Specifically, CalMRL leverages the priors and the inherent connections among modalities to model the imputation for the missing ones at the representation level. To resolve the optimization dilemma, we employ a bi-step learning method with the closed-form solution of the posterior distribution of shared latents. We validate its mitigation of anchor shift and convergence with theoretical guidance. By equipping the calibrated alignment with the existing advanced method, we offer new flexibility to absorb data with missing modalities, which is originally unattainable. Extensive experiments and comprehensive analyses demonstrate the superiority of CalMRL. Our code, model checkpoints, and evaluation raw data will be publicly available.

  • 7 authors
·
Nov 14, 2025

A Misclassification Network-Based Method for Comparative Genomic Analysis

Classifying genome sequences based on metadata has been an active area of research in comparative genomics for decades with many important applications across the life sciences. Established methods for classifying genomes can be broadly grouped into sequence alignment-based and alignment-free models. Conventional alignment-based models rely on genome similarity measures calculated based on local sequence alignments or consistent ordering among sequences. However, such methods are computationally expensive when dealing with large ensembles of even moderately sized genomes. In contrast, alignment-free (AF) approaches measure genome similarity based on summary statistics in an unsupervised setting and are efficient enough to analyze large datasets. However, both alignment-based and AF methods typically assume fixed scoring rubrics that lack the flexibility to assign varying importance to different parts of the sequences based on prior knowledge. In this study, we integrate AI and network science approaches to develop a comparative genomic analysis framework that addresses these limitations. Our approach, termed the Genome Misclassification Network Analysis (GMNA), simultaneously leverages misclassified instances, a learned scoring rubric, and label information to classify genomes based on associated metadata and better understand potential drivers of misclassification. We evaluate the utility of the GMNA using Naive Bayes and convolutional neural network models, supplemented by additional experiments with transformer-based models, to construct SARS-CoV-2 sampling location classifiers using over 500,000 viral genome sequences and study the resulting network of misclassifications. We demonstrate the global health potential of the GMNA by leveraging the SARS-CoV-2 genome misclassification networks to investigate the role human mobility played in structuring geographic clustering of SARS-CoV-2.

  • 3 authors
·
Dec 9, 2024

Why Are My Prompts Leaked? Unraveling Prompt Extraction Threats in Customized Large Language Models

The drastic increase of large language models' (LLMs) parameters has led to a new research direction of fine-tuning-free downstream customization by prompts, i.e., task descriptions. While these prompt-based services (e.g. OpenAI's GPTs) play an important role in many businesses, there has emerged growing concerns about the prompt leakage, which undermines the intellectual properties of these services and causes downstream attacks. In this paper, we analyze the underlying mechanism of prompt leakage, which we refer to as prompt memorization, and develop corresponding defending strategies. By exploring the scaling laws in prompt extraction, we analyze key attributes that influence prompt extraction, including model sizes, prompt lengths, as well as the types of prompts. Then we propose two hypotheses that explain how LLMs expose their prompts. The first is attributed to the perplexity, i.e. the familiarity of LLMs to texts, whereas the second is based on the straightforward token translation path in attention matrices. To defend against such threats, we investigate whether alignments can undermine the extraction of prompts. We find that current LLMs, even those with safety alignments like GPT-4, are highly vulnerable to prompt extraction attacks, even under the most straightforward user attacks. Therefore, we put forward several defense strategies with the inspiration of our findings, which achieve 83.8\% and 71.0\% drop in the prompt extraction rate for Llama2-7B and GPT-3.5, respectively. Source code is avaliable at https://github.com/liangzid/PromptExtractionEval.

  • 5 authors
·
Aug 5, 2024

Non-Uniform Spatial Alignment Errors in sUAS Imagery From Wide-Area Disasters

This work presents the first quantitative study of alignment errors between small uncrewed aerial systems (sUAS) geospatial imagery and a priori building polygons and finds that alignment errors are non-uniform and irregular. The work also introduces a publicly available dataset of imagery, building polygons, and human-generated and curated adjustments that can be used to evaluate existing strategies for aligning building polygons with sUAS imagery. There are no efforts that have aligned pre-existing spatial data with sUAS imagery, and thus, there is no clear state of practice. However, this effort and analysis show that the translational alignment errors present in this type of data, averaging 82px and an intersection over the union of 0.65, which would induce further errors and biases in downstream machine learning systems unless addressed. This study identifies and analyzes the translational alignment errors of 21,619 building polygons in fifty-one orthomosaic images, covering 16787.2 Acres (26.23 square miles), constructed from sUAS raw imagery from nine wide-area disasters (Hurricane Ian, Hurricane Harvey, Hurricane Michael, Hurricane Ida, Hurricane Idalia, Hurricane Laura, the Mayfield Tornado, the Musset Bayou Fire, and the Kilauea Eruption). The analysis finds no uniformity among the angle and distance metrics of the building polygon alignments as they present an average degree variance of 0.4 and an average pixel distance variance of 0.45. This work alerts the sUAS community to the problem of spatial alignment and that a simple linear transform, often used to align satellite imagery, will not be sufficient to align spatial data in sUAS orthomosaic imagery.

  • 6 authors
·
May 10, 2024

CREST: Cross-modal Resonance through Evidential Deep Learning for Enhanced Zero-Shot Learning

Zero-shot learning (ZSL) enables the recognition of novel classes by leveraging semantic knowledge transfer from known to unknown categories. This knowledge, typically encapsulated in attribute descriptions, aids in identifying class-specific visual features, thus facilitating visual-semantic alignment and improving ZSL performance. However, real-world challenges such as distribution imbalances and attribute co-occurrence among instances often hinder the discernment of local variances in images, a problem exacerbated by the scarcity of fine-grained, region-specific attribute annotations. Moreover, the variability in visual presentation within categories can also skew attribute-category associations. In response, we propose a bidirectional cross-modal ZSL approach CREST. It begins by extracting representations for attribute and visual localization and employs Evidential Deep Learning (EDL) to measure underlying epistemic uncertainty, thereby enhancing the model's resilience against hard negatives. CREST incorporates dual learning pathways, focusing on both visual-category and attribute-category alignments, to ensure robust correlation between latent and observable spaces. Moreover, we introduce an uncertainty-informed cross-modal fusion technique to refine visual-attribute inference. Extensive experiments demonstrate our model's effectiveness and unique explainability across multiple datasets. Our code and data are available at: https://github.com/JethroJames/CREST

  • 8 authors
·
Apr 15, 2024

Automatic Disfluency Detection from Untranscribed Speech

Speech disfluencies, such as filled pauses or repetitions, are disruptions in the typical flow of speech. Stuttering is a speech disorder characterized by a high rate of disfluencies, but all individuals speak with some disfluencies and the rates of disfluencies may by increased by factors such as cognitive load. Clinically, automatic disfluency detection may help in treatment planning for individuals who stutter. Outside of the clinic, automatic disfluency detection may serve as a pre-processing step to improve natural language understanding in downstream applications. With this wide range of applications in mind, we investigate language, acoustic, and multimodal methods for frame-level automatic disfluency detection and categorization. Each of these methods relies on audio as an input. First, we evaluate several automatic speech recognition (ASR) systems in terms of their ability to transcribe disfluencies, measured using disfluency error rates. We then use these ASR transcripts as input to a language-based disfluency detection model. We find that disfluency detection performance is largely limited by the quality of transcripts and alignments. We find that an acoustic-based approach that does not require transcription as an intermediate step outperforms the ASR language approach. Finally, we present multimodal architectures which we find improve disfluency detection performance over the unimodal approaches. Ultimately, this work introduces novel approaches for automatic frame-level disfluency and categorization. In the long term, this will help researchers incorporate automatic disfluency detection into a range of applications.

  • 3 authors
·
Oct 31, 2023

Unify, Align and Refine: Multi-Level Semantic Alignment for Radiology Report Generation

Automatic radiology report generation has attracted enormous research interest due to its practical value in reducing the workload of radiologists. However, simultaneously establishing global correspondences between the image (e.g., Chest X-ray) and its related report and local alignments between image patches and keywords remains challenging. To this end, we propose an Unify, Align and then Refine (UAR) approach to learn multi-level cross-modal alignments and introduce three novel modules: Latent Space Unifier (LSU), Cross-modal Representation Aligner (CRA) and Text-to-Image Refiner (TIR). Specifically, LSU unifies multimodal data into discrete tokens, making it flexible to learn common knowledge among modalities with a shared network. The modality-agnostic CRA learns discriminative features via a set of orthonormal basis and a dual-gate mechanism first and then globally aligns visual and textual representations under a triplet contrastive loss. TIR boosts token-level local alignment via calibrating text-to-image attention with a learnable mask. Additionally, we design a two-stage training procedure to make UAR gradually grasp cross-modal alignments at different levels, which imitates radiologists' workflow: writing sentence by sentence first and then checking word by word. Extensive experiments and analyses on IU-Xray and MIMIC-CXR benchmark datasets demonstrate the superiority of our UAR against varied state-of-the-art methods.

  • 6 authors
·
Mar 28, 2023

Cross-Modal Implicit Relation Reasoning and Aligning for Text-to-Image Person Retrieval

Text-to-image person retrieval aims to identify the target person based on a given textual description query. The primary challenge is to learn the mapping of visual and textual modalities into a common latent space. Prior works have attempted to address this challenge by leveraging separately pre-trained unimodal models to extract visual and textual features. However, these approaches lack the necessary underlying alignment capabilities required to match multimodal data effectively. Besides, these works use prior information to explore explicit part alignments, which may lead to the distortion of intra-modality information. To alleviate these issues, we present IRRA: a cross-modal Implicit Relation Reasoning and Aligning framework that learns relations between local visual-textual tokens and enhances global image-text matching without requiring additional prior supervision. Specifically, we first design an Implicit Relation Reasoning module in a masked language modeling paradigm. This achieves cross-modal interaction by integrating the visual cues into the textual tokens with a cross-modal multimodal interaction encoder. Secondly, to globally align the visual and textual embeddings, Similarity Distribution Matching is proposed to minimize the KL divergence between image-text similarity distributions and the normalized label matching distributions. The proposed method achieves new state-of-the-art results on all three public datasets, with a notable margin of about 3%-9% for Rank-1 accuracy compared to prior methods.

  • 2 authors
·
Mar 22, 2023

Towards Generalisable Video Moment Retrieval: Visual-Dynamic Injection to Image-Text Pre-Training

The correlation between the vision and text is essential for video moment retrieval (VMR), however, existing methods heavily rely on separate pre-training feature extractors for visual and textual understanding. Without sufficient temporal boundary annotations, it is non-trivial to learn universal video-text alignments. In this work, we explore multi-modal correlations derived from large-scale image-text data to facilitate generalisable VMR. To address the limitations of image-text pre-training models on capturing the video changes, we propose a generic method, referred to as Visual-Dynamic Injection (VDI), to empower the model's understanding of video moments. Whilst existing VMR methods are focusing on building temporal-aware video features, being aware of the text descriptions about the temporal changes is also critical but originally overlooked in pre-training by matching static images with sentences. Therefore, we extract visual context and spatial dynamic information from video frames and explicitly enforce their alignments with the phrases describing video changes (e.g. verb). By doing so, the potentially relevant visual and motion patterns in videos are encoded in the corresponding text embeddings (injected) so to enable more accurate video-text alignments. We conduct extensive experiments on two VMR benchmark datasets (Charades-STA and ActivityNet-Captions) and achieve state-of-the-art performances. Especially, VDI yields notable advantages when being tested on the out-of-distribution splits where the testing samples involve novel scenes and vocabulary.

  • 5 authors
·
Feb 28, 2023