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Oct 15

EditScore: Unlocking Online RL for Image Editing via High-Fidelity Reward Modeling

Instruction-guided image editing has achieved remarkable progress, yet current models still face challenges with complex instructions and often require multiple samples to produce a desired result. Reinforcement Learning (RL) offers a promising solution, but its adoption in image editing has been severely hindered by the lack of a high-fidelity, efficient reward signal. In this work, we present a comprehensive methodology to overcome this barrier, centered on the development of a state-of-the-art, specialized reward model. We first introduce EditReward-Bench, a comprehensive benchmark to systematically evaluate reward models on editing quality. Building on this benchmark, we develop EditScore, a series of reward models (7B-72B) for evaluating the quality of instruction-guided image editing. Through meticulous data curation and filtering, EditScore effectively matches the performance of learning proprietary VLMs. Furthermore, coupled with an effective self-ensemble strategy tailored for the generative nature of EditScore, our largest variant even surpasses GPT-5 in the benchmark. We then demonstrate that a high-fidelity reward model is the key to unlocking online RL for image editing. Our experiments show that, while even the largest open-source VLMs fail to provide an effective learning signal, EditScore enables efficient and robust policy optimization. Applying our framework to a strong base model, OmniGen2, results in a final model that shows a substantial and consistent performance uplift. Overall, this work provides the first systematic path from benchmarking to reward modeling to RL training in image editing, showing that a high-fidelity, domain-specialized reward model is the key to unlocking the full potential of RL in this domain.

Efficient Multi-turn RL for GUI Agents via Decoupled Training and Adaptive Data Curation

Vision-language model (VLM) based GUI agents show promise for automating complex desktop and mobile tasks, but face significant challenges in applying reinforcement learning (RL): (1) slow multi-turn interactions with GUI environments for policy rollout, and (2) insufficient high-quality agent-environment interactions for policy learning. To address these challenges, we propose DART, a Decoupled Agentic RL Training framework for GUI agents, which coordinates heterogeneous modules in a highly decoupled manner. DART separates the training system into four asynchronous modules: environment cluster, rollout service, data manager, and trainer. This design enables non-blocking communication, asynchronous training, rollout-wise trajectory sampling, and per-worker model synchronization, significantly improving the system efficiency: 1.6*GPU utilization for rollout, 1.9* training throughput, and 5.5* environment utilization. To facilitate effective learning from abundant samples, we introduce an adaptive data curation scheme: (1) pre-collecting successful trajectories for challenging tasks to supplement sparse success in online sampling; (2) dynamically adjusting rollout numbers and trajectory lengths based on task difficulty; (3) training selectively on high-entropy steps to prioritize critical decisions; (4) stabilizing learning via truncated importance sampling for policy mismatch between policy rollout and updating. On the OSWorld benchmark, DART-GUI-7B achieves a 42.13% task success rate, a 14.61% absolute gain over the base model, and 7.34% higher than open-source SOTA. We will fully open-source our training framework, data, and model checkpoints via computer-use-agents.github.io/dart-gui, which we believe is a timely contribution to the open-source community of agentic RL training.

The Markovian Thinker

Reinforcement learning (RL) has recently become a strong recipe for training reasoning LLMs that produce long chains of thought (LongCoT). Yet the standard RL "thinking environment", where the state is the prompt plus all prior reasoning tokens, makes the state unbounded and forces attention-based policies to pay quadratic compute as thoughts lengthen. We revisit the environment itself. We propose Markovian Thinking, a paradigm in which the policy advances reasoning while conditioning on a constant-size state, decoupling thinking length from context size. As an immediate consequence this yields linear compute with constant memory. We instantiate this idea with Delethink, an RL environment that structures reasoning into fixed-size chunks. Within each chunk, the model thinks as usual; at the boundary, the environment resets the context and reinitializes the prompt with a short carryover. Through RL, the policy learns to write a textual state near the end of each chunk sufficient for seamless continuation of reasoning after reset. Trained in this environment, an R1-Distill 1.5B model reasons in 8K-token chunks yet thinks up to 24K tokens, matching or surpassing LongCoT-RL trained with a 24K budget. With test-time scaling, Delethink continues to improve where LongCoT plateaus. The effect of linear compute is substantial: we empirically estimate at 96K average thinking length LongCoT-RL costs 27 H100-months vs. 7 for Delethink. Analysis at RL initialization shows off-the-shelf reasoning models (1.5B-120B) often sample Markovian traces zero-shot across diverse benchmarks, providing positive samples that make RL effective at scale. Our results show that redesigning the thinking environment is a powerful lever: it enables very long reasoning without quadratic overhead and opens a path toward efficient, scalable reasoning LLMs.

Training Diffusion Language Models for Black-Box Optimization

We study offline black-box optimization (BBO), aiming to discover improved designs from an offline dataset of designs and labels, a problem common in robotics and DNA with limited labeled samples. While recent work applies autoregressive LLMs to BBO by formatting tasks as natural-language prompts, their left-to-right design generation struggles to capture the strong bidirectional dependencies inherent in design problems. To address this, we propose adapting diffusion LLMs to offline BBO to leverage their bidirectional modeling capabilities. However, a domain gap exists between the natural text pre-training of diffusion LLMs and the heterogeneous signals in BBO (prompts, designs, and labels). To bridge this gap, we construct a unified prompt--response corpus and introduce delimiter tokens to explicitly mark field boundaries for domain adaptation. We further propose a two-stage post-training framework to align the diffusion LLM generation with high-label designs. The first stage performs supervised fine-tuning on the unified dataset via masked-response prediction, and the second stage adopts reinforcement learning with rewards defined by label improvements. Our method achieves state-of-the-art results on Design-Bench under small-data settings with highly efficient training, requiring only 1.5 H100 GPU hours for discrete tasks. Code for our work is available here: https://github.com/zpointS/DiBO.

MassAlloc Attention: Let Attention Allocate Its Own Compute

FullAttn often assigns negligible normalized mass to much of the causal score space, yet dense kernels execute the complete post-score path after forming each QK tile. We introduce MALA, a fused attention primitive that preserves score access to every legal causal interaction and uses normalized contribution to allocate post-score computation. Forward uses its evolving online-softmax normalizer, while backward reuses the finalized normalizer to derive nested retained support using only standard attention state. A common tolerance governs training and inference, allowing for adaptive retention of the work. MALA reduces low-contribution post-score computation. A matched-work study at 8K isolates the benefit of distribution-adaptive allocation: under exactly matched total post-score work, MALA approaches a per-instance reference-mass oracle, with mean omitted mass of 0.0188% versus 0.0182%. Across context lengths from 1K to 32K tokens, the same tolerance maintains low output and gradient errors relative to the reference. Across a broader controlled associative-recall comparison, MALA closely tracks FullAttn as context grows, reaching 89.67% accuracy at 8K compared with 89.97% for FullAttn. In an attention-operator benchmark at 128K tokens with tensor parallelism, MALA reduces forward and backward latency during training by 2.2x and 3.0x and decoding latency during inference by 1.6x relative to FullAttn. Across scaling-law training from 0.6B to 14B parameters, MALA closely tracks FullAttn in perplexity while reducing total training FLOPs. The resulting 14B models and 32B models from separate continued training achieve comparable knowledge, reasoning, and long-context retrieval scores to FullAttn. These results indicate that allocating post-score computation according to normalized attention contributions can retain the evaluated capabilities of FullAttn while reducing attention computation.

CoWindow Attention: Full Causal Coverage Is a Collective Property

FullAttn repeatedly exposes the complete causal history to every attention head, creating substantial redundant computation and memory traffic even with IO-efficient dense kernels. We introduce CoWA, a structured attention architecture that distributes access to the causal history across KV heads. All heads share near-diagonal and prefix-sink windows, while complementary long-range windows partition the remaining history. Their union provides full causal coverage although each head attends sparsely to distant tokens. This position-defined attention pattern requires no learned router or indexer, is used consistently during training and inference, and aligns with KV-head tensor parallelism. A window-matched ablation at 8K isolates the effect of complementary long-range allocation: CoWA with 100% collective coverage reaches 89.73% accuracy, compared with 89.97% for FullAttn, while duplicated long-range windows perform substantially worse. Across a broader controlled associative-recall comparison with matched token budgets, CoWA closely tracks FullAttn as the context grows, whereas other sparse patterns lose a substantial fraction of the associations. In an attention-operator benchmark at 128K tokens with tensor parallelism, CoWA reduces forward and backward latency during training by 7.4x and 8.6x and decoding latency during inference by 3.0x over FullAttn. Its per-rank peak operator memory matches FullAttn during training and is 7.6x lower during decoding. Across scaling-law training from 0.6B to 14B parameters, CoWA closely tracks FullAttn in perplexity while reducing total training FLOPs. The resulting 14B models and 32B models from separate continued training achieve comparable knowledge, reasoning, and long-context retrieval scores to FullAttn. These results show that full causal coverage can be a collective property of the head ensemble rather than a duplicated property of every head.

Geometry of Values: Task Vector Composition for Ethical Preference Alignment in Language Models

Large Language Models (LLMs) are increasingly deployed in applications that must weigh clashing moral values, yet even strong models exhibit hidden biases and brittle instruction-following across languages. We introduce a 12,000-instance dataset of two-option dilemmas covering pairwise three value conflicts: Honesty vs. Justice, Justice vs. Autonomy, and Autonomy vs. Honesty, along with their translations into Hindi, Arabic, Spanish, and Chinese, to probe cross-lingual behavior. Benchmarking on GPT-5-mini reveals that it consistently favors Honesty over Autonomy across all five languages when no policy is given. The Llama-3.2-1/3B models exhibit strong first-option bias; however, both plain fine-tuning and Direct Preference Optimization fine-tuning effectively remove this bias, increasing accuracy to greater than 98%. In order to decouple the effect of learning correlations in the dataset from abstract values, we propose a task vector transfer based experiment where after computing the task vectors for a direction of value preference we orthogonalize it with respect to the general instruction following vector. Our experiment shows that this method is effective in isolating the direction of the specific value preference that can successfully be used to conduct task arithmetic to obtain a model with the opposite stance.

Flash-dLLM: IO-Aware KV Caching and Parallel Decoding for Fast, Memory-Efficient Diffusion LLMs

Diffusion Large Language Models (dLLMs) have recently emerged as a promising alternative to autoregressive LLMs by enabling non-autoregressive text generation. However, their practical deployment remains limited by inefficient inference, largely due to the absence of effective Key-Value (KV) caching and scalable parallel decoding mechanisms. Existing acceleration methods typically study KV caching and parallel decoding in isolation, overlooking the I/O bottlenecks that arise when cache reuse and parallel token verification are jointly applied. In this work, we introduce Flash-dLLM, a training-free inference acceleration framework for fast and memory-efficient dLLMs. Flash-dLLM first identifies GPU memory I/O as a dominant bottleneck in KV-cache-enabled dLLM inference and addresses it with an I/O-aware fused KV-cache kernel that reduces redundant memory movement. Building on this optimized cache mechanism, Flash-dLLM further proposes an efficient KV-cache-driven draft-and-verify decoding strategy, where the dLLM itself serves as both drafter and verifier without requiring an auxiliary model. This unified design enables faster decoding while preserving generation quality and improving scalability to longer sequences and larger batch size. Extensive experiments on mathematical reasoning and code-generation benchmarks demonstrate that Flash-dLLM consistently outperforms existing state-of-the-art dLLM acceleration methods in both inference speed and memory efficiency. In particular, it achieves 5.1times and 11.0times speedups over prior strongest baseline Elastic-Cache on GSM8K and HumanEval, respectively.

Hard Vision, Easy Vision: What GPT-6 Astra Reveals Across Computer Vision

Frontier general-purpose systems are rapidly expanding beyond visual understanding into capabilities traditionally handled by dedicated computer-vision models. As these capabilities expand, a central question for the computer-vision community is how far this reach extends, and what remains hard. We evaluate GPT-6 Astra alongside five frontier general-purpose AI systems across 34 capabilities and 55 benchmarks spanning nine areas of computer vision. We compare their performance with dedicated models and humans where suitable references are available. Astra demonstrates broad visual capability, with substantial gains over other frontier systems in visual and spatial reasoning and several forms of structured prediction. Across the state-of-the-art systems, a consistent pattern emerges. Capabilities involving semantic interpretation, reasoning, and object-centric prediction increasingly approach or reach available reference levels. In contrast, larger gaps remain when tasks require metric geometric accuracy, faithful reconstruction, temporally consistent dense prediction, or specialized fine-grained visual knowledge. Additional reasoning and specialist tools close selected gaps, but their benefits vary across capabilities. These results map a changing landscape of computer vision in which increasingly sophisticated visual tasks are accessible through a general-purpose interface, while precise and fidelity-sensitive perception remains an important frontier.

Omni-Embed-Mini: Binding Modalities Without Forgetting via Dense Distillation

Extending a text embedding model to new modalities typically degrades text retrieval quality, and existing omni-modal embedders compensate with multi-billion parameters. We present Omni-Embed-Mini, a 0.9B-parameter model that maps text, speech, audio, images, video, and visually-rich documents into a single shared cosine space without updating any text-side parameter. Our key insight is that the teacher signal requires no separate embedding model: each media sample is paired with a dense cascaded caption, and the teacher target is simply the frozen backbone's own embedding of that caption. Because teacher and student share the same backbone weights, they inhabit byte-identical geometry, and lightweight projectors plus phased LoRA adapters on the modality encoders suffice for alignment. Training combines a Matryoshka SigLIP contrastive loss with an online hybrid hard-negative miner whose negatives sharpen as the encoder improves. The recipe carries over to a 2.3B variant by swapping in a native vision-language backbone. Omni-Embed-Mini-0.9B keeps its text weights bit-identical to the backbone, so training cannot regress text retrieval (49.57 nDCG@10 on MTEB-v2 BEIR-8), while extending it to five additional modalities, and is ~2.7x to 9.5x smaller than every open omni embedder we compare against. The 2.3B variant is competitive with the closed gemini-embedding-2, edging ahead of it on the overall-modality average. Models, code, data and evaluation harness are on our project page: https://omniembed.cvmbzuai.com

Ego2Act: Evaluating Goal-Directed Manipulation in Egocentric Video Generation

Video generation models are increasingly being explored as world simulators for embodied planning and learning. To do so effectively, these models must not only generate visually appealing frames, but also predict how environments dynamically evolve when executing goal-directed actions. While evaluating these capabilities is crucial, existing benchmarks focus mainly on single short actions or step-by-step instructions. This leaves multi-step physical reasoning underexplored, especially in egocentric video generation that requires planning to simulate proper execution to accomplish high-level goals by carrying out multiple real-world manipulations. We introduce Ego2Act, a goal-directed benchmark featuring 2,640 videos from 110 real-world tasks across day-to-day settings, varying object clutter and multi-step complexity. Given an initial scene image and a high-level goal, Ego2Act evaluates whether video generation models can produce realistic egocentric videos of a hand manipulating objects to carry out the task. To support scalable evaluation, we also introduce Ego2ActJudge, a reference-free evaluation pipeline that achieves better task completion and physics plausibility evaluation alignment with human consensus compared to relevant baselines. Our findings reveal that models' generated simulations often skip or partially execute steps, leaving later steps missing dependent states, which leads to unfulfilled goal. Furthermore, models consistently fail at fine-grained physical dynamics, particularly during complex object manipulation and persistent world modeling. We hope Ego2Act provides a rigorous testbed for advancing video models toward physically plausible, goal-directed simulation.

Certification of Real Images through Calibrated Content Authentication

Generative models can synthesize high-quality inauthentic multimedia content that is already being misused at scale. We evaluate twenty deepfake detectors against ten generators released in the last four years and find accuracy decreasing over time, from near-perfect 99.5% to 76%. Adversarial perturbations further reduce every baseline detector to below 2% accuracy, effectively inverting the detector's assigned label. We argue that this unreliability reflects a fundamental ambiguity: generators can reproduce authentic content exactly (e.g., through memorization), so content alone cannot reveal the true provenance label.For this reason, content produced by a generator must admit a faithful reconstruction by that same generator, and finding such a reconstruction makes synthetic provenance plausible and authenticity plausibly deniable.We therefore propose and evaluate a detection paradigm that outputs a calibrated prediction of whether authenticity is plausibly deniable: a faithful reconstruction by any known generator establishes plausible deniability, while calibration bounds how often content from known generators fails to be reproduced. Our evaluation shows that (i) our detector can be calibrated so that at most 1% of generated content is wrongly certified, an operating point at which most baseline detectors reach near-zero recall, including the strongest with 93% accuracy; (ii) calibrating a stricter security threshold on attacked samples preserves this bound against adaptive adversaries within the evaluated bounded-perturbation attack space, whose perturbations break every baseline, but does not cover arbitrary adversarial transformations; and (iii) post-hoc verifiability is eroding, as 1,116 of 3,000 Reddit images resist reproduction by a 2022 generator, but only 55 to 79 resist reproduction by 2024 generators.

Noise Out, Bias In: Targeted Bias Injection in Diffusion Language Models via Closed-Loop Activation Steering

Masked diffusion language models (dLLMs) generate text by iteratively denoising masked positions, re-predicting each token multiple times before it is committed. An autoregressive decoder exposes an answer's distribution once, at the step that commits it; a dLLM exposes it at every denoising step before commitment, and we show that an adversary can exploit this. Since an answer remains open to revision over many denoising steps, an adversary with access to internal activations can watch how likely the model is to produce a chosen answer and adjust the intervention accordingly. Building on this observation, we study targeted bias injection, an attack that steers a frozen dLLM toward a demographic answer selected by the adversary. The attack uses a simple proportional-integral (PI) controller that tracks the target-answer probability during denoising and adapts the strength of a steering vector on the fly. On ambiguous BBQ questions where the correct answer is abstention, our attack raises LLaDA-8B-Instruct's preference for the targeted group from 1.8 to 16.7 percentage points, more than three times the strongest fixed-strength steering baseline, and on SocialStigmaQA it raises the selection of stigmatizing answers from 17.6% to 58.1%. Fitted to other demographic targets, the same attack shifts answers by up to 37 percentage points, and each attack takes about 40 minutes on one GPU. On the primary target, feedback is what makes the attack work: constant steering at the same average strength over the token-committing steps produces a far smaller shift while corrupting nearly three times as many outputs, and a constant strength set separately for each example still falls well short. Our findings identify the denoising trajectory as a new control channel in dLLMs and call for bias audits that examine the serving stack rather than the frozen model alone.

WorldGuide: Goal-Directed Video World Model for Procedural Task Execution

Video generators and video-based world models can synthesize plausible visual trajectories, but long-horizon procedural tasks require generation to adapt to what has actually been produced. A model must determine the next action from its generated state, execute that action, and recognize when the task is complete. Open-loop generation cannot adapt to execution outcomes, while existing closed-loop systems often rely on pretrained executors or indirect verification. This leaves a gap between deciding an action and successfully realizing it. We formulate procedural video generation as closed-loop task execution in visual world space and introduce WorldGuide. Given only an initial image and a task goal, WorldGuide predicts an atomic action, generates its corresponding video clip, and uses the generated result to select the next action or terminate. The Planner and Executor are trained on the same step-level procedural demonstrations: the Planner learns to predict the next atomic action or task completion from visual progress, while the Executor is directly trained to realize the predicted actions. Hierarchical visual memory maintains state across long-horizon execution with bounded history token cost. Due to the lack of step-level action-video supervision for joint planner-executor training, we introduce WorldGuide Bench: approximately 59K step-annotated videos across 245 tasks and 27 procedural categories. WorldGuide achieves a 33.33\% Task Success on WorldGuide-Bench, compared with 29.90\% for the strong recent video model MiniMax-H3, even though MiniMax-H3 receives reference action plans, and achieves 47.69\% on VideoCraft-Bench compared with 32.73\% for MiniMax-H3 under goal-only conditioning. These results demonstrate the importance of coupling planning with learned execution for goal-directed procedural video generation.

Sparks of Artificial General Intelligence: Early experiments with GPT-4

Artificial intelligence (AI) researchers have been developing and refining large language models (LLMs) that exhibit remarkable capabilities across a variety of domains and tasks, challenging our understanding of learning and cognition. The latest model developed by OpenAI, GPT-4, was trained using an unprecedented scale of compute and data. In this paper, we report on our investigation of an early version of GPT-4, when it was still in active development by OpenAI. We contend that (this early version of) GPT-4 is part of a new cohort of LLMs (along with ChatGPT and Google's PaLM for example) that exhibit more general intelligence than previous AI models. We discuss the rising capabilities and implications of these models. We demonstrate that, beyond its mastery of language, GPT-4 can solve novel and difficult tasks that span mathematics, coding, vision, medicine, law, psychology and more, without needing any special prompting. Moreover, in all of these tasks, GPT-4's performance is strikingly close to human-level performance, and often vastly surpasses prior models such as ChatGPT. Given the breadth and depth of GPT-4's capabilities, we believe that it could reasonably be viewed as an early (yet still incomplete) version of an artificial general intelligence (AGI) system. In our exploration of GPT-4, we put special emphasis on discovering its limitations, and we discuss the challenges ahead for advancing towards deeper and more comprehensive versions of AGI, including the possible need for pursuing a new paradigm that moves beyond next-word prediction. We conclude with reflections on societal influences of the recent technological leap and future research directions.

  • 14 authors
·
Mar 22, 2023

Artificial intelligence in cyber physical systems

This article conducts a literature review of current and future challenges in the use of artificial intelligence (AI) in cyber physical systems. The literature review is focused on identifying a conceptual framework for increasing resilience with AI through automation supporting both, a technical and human level. The methodology applied resembled a literature review and taxonomic analysis of complex internet of things (IoT) interconnected and coupled cyber physical systems. There is an increased attention on propositions on models, infrastructures and frameworks of IoT in both academic and technical papers. These reports and publications frequently represent a juxtaposition of other related systems and technologies (e.g. Industrial Internet of Things, Cyber Physical Systems, Industry 4.0 etc.). We review academic and industry papers published between 2010 and 2020. The results determine a new hierarchical cascading conceptual framework for analysing the evolution of AI decision-making in cyber physical systems. We argue that such evolution is inevitable and autonomous because of the increased integration of connected devices (IoT) in cyber physical systems. To support this argument, taxonomic methodology is adapted and applied for transparency and justifications of concepts selection decisions through building summary maps that are applied for designing the hierarchical cascading conceptual framework.

  • 5 authors
·
Mar 11, 2019

Decolonial AI: Decolonial Theory as Sociotechnical Foresight in Artificial Intelligence

This paper explores the important role of critical science, and in particular of post-colonial and decolonial theories, in understanding and shaping the ongoing advances in artificial intelligence. Artificial Intelligence (AI) is viewed as amongst the technological advances that will reshape modern societies and their relations. Whilst the design and deployment of systems that continually adapt holds the promise of far-reaching positive change, they simultaneously pose significant risks, especially to already vulnerable peoples. Values and power are central to this discussion. Decolonial theories use historical hindsight to explain patterns of power that shape our intellectual, political, economic, and social world. By embedding a decolonial critical approach within its technical practice, AI communities can develop foresight and tactics that can better align research and technology development with established ethical principles, centring vulnerable peoples who continue to bear the brunt of negative impacts of innovation and scientific progress. We highlight problematic applications that are instances of coloniality, and using a decolonial lens, submit three tactics that can form a decolonial field of artificial intelligence: creating a critical technical practice of AI, seeking reverse tutelage and reverse pedagogies, and the renewal of affective and political communities. The years ahead will usher in a wave of new scientific breakthroughs and technologies driven by AI research, making it incumbent upon AI communities to strengthen the social contract through ethical foresight and the multiplicity of intellectual perspectives available to us; ultimately supporting future technologies that enable greater well-being, with the goal of beneficence and justice for all.

  • 3 authors
·
Jul 8, 2020

Artificial Intelligence in Mental Health and Well-Being: Evolution, Current Applications, Future Challenges, and Emerging Evidence

Artificial Intelligence (AI) is a broad field that is upturning mental health care in many ways, from addressing anxiety, depression, and stress to increasing access, personalization of treatment, and real-time monitoring that enhances patient outcomes. The current paper discusses the evolution, present application, and future challenges in the field of AI for mental health and well-being. From the early chatbot models, such as ELIZA, to modern machine learning systems, the integration of AI in mental health has grown rapidly to augment traditional treatment and open innovative solutions. AI-driven tools provide continuous support, offering personalized interventions and addressing issues such as treatment access and patient stigma. AI also enables early diagnosis through the analysis of complex datasets, including speech patterns and social media behavior, to detect early signs of conditions like depression and Post-Traumatic Stress Disorder (PTSD). Ethical challenges persist, however, most notably around privacy, data security, and algorithmic bias. With AI at the core of mental health care, there is a dire need to develop strong ethical frameworks that ensure patient rights are protected, access is equitable, and transparency is maintained in AI applications. Going forward, the role of AI in mental health will continue to evolve, and continued research and policy development will be needed to meet the diverse needs of patients while mitigating associated risks.

  • 1 authors
·
Dec 13, 2024

Artificial Intelligence-derived Vascular Age from Photoplethysmography: A Novel Digital Biomarker for Cardiovascular Health

With the increasing availability of wearable devices, photoplethysmography (PPG) has emerged as a promising non-invasive tool for monitoring human hemodynamics. We propose a deep learning framework to estimate vascular age (AI-vascular age) from PPG signals, incorporating a distribution-aware loss to address biases caused by imbalanced data. The model was developed using data from the UK Biobank (UKB), with 98,672 participants in the development cohort and 113,559 participants (144,683 data pairs) for clinical evaluation. After adjusting for key confounders, individuals with a vascular age gap (AI-vascular age minus calendar age) exceeding 9 years had a significantly higher risk of major adverse cardiovascular and cerebrovascular events (MACCE) (HR = 2.37, p < 0.005) and secondary outcomes, including diabetes (HR = 2.69, p < 0.005), hypertension (HR = 2.88, p < 0.005), coronary heart disease (HR = 2.20, p < 0.005), heart failure (HR = 2.15, p < 0.005), myocardial infarction (HR = 2.51, p < 0.005), stroke (HR = 2.55, p < 0.005), and all-cause mortality (HR = 2.51, p < 0.005). Conversely, participants with a vascular age gap below -9 years exhibited a significantly lower incidence of these outcomes. We further evaluated the longitudinal applicability of AI-vascular age using serial PPG data from the UKB, demonstrating its value in risk stratification by leveraging AI-vascular age at two distinct time points to predict future MACCE incidence. External validation was performed on a MIMIC-III-derived cohort (n = 2,343), where each one-year increase in vascular age gap was significantly associated with elevated in-hospital mortality risk (OR = 1.02, p < 0.005). In conclusion, our study establishes AI-vascular age as a novel, non-invasive digital biomarker for cardiovascular health assessment.

  • 5 authors
·
Feb 18, 2025

Probabilistic Artificial Intelligence

Artificial intelligence commonly refers to the science and engineering of artificial systems that can carry out tasks generally associated with requiring aspects of human intelligence, such as playing games, translating languages, and driving cars. In recent years, there have been exciting advances in learning-based, data-driven approaches towards AI, and machine learning and deep learning have enabled computer systems to perceive the world in unprecedented ways. Reinforcement learning has enabled breakthroughs in complex games such as Go and challenging robotics tasks such as quadrupedal locomotion. A key aspect of intelligence is to not only make predictions, but reason about the uncertainty in these predictions, and to consider this uncertainty when making decisions. This is what this manuscript on "Probabilistic Artificial Intelligence" is about. The first part covers probabilistic approaches to machine learning. We discuss the differentiation between "epistemic" uncertainty due to lack of data and "aleatoric" uncertainty, which is irreducible and stems, e.g., from noisy observations and outcomes. We discuss concrete approaches towards probabilistic inference and modern approaches to efficient approximate inference. The second part of the manuscript is about taking uncertainty into account in sequential decision tasks. We consider active learning and Bayesian optimization -- approaches that collect data by proposing experiments that are informative for reducing the epistemic uncertainty. We then consider reinforcement learning and modern deep RL approaches that use neural network function approximation. We close by discussing modern approaches in model-based RL, which harness epistemic and aleatoric uncertainty to guide exploration, while also reasoning about safety.

  • 2 authors
·
Feb 7, 2025

Cognitive Castes: Artificial Intelligence, Epistemic Stratification, and the Dissolution of Democratic Discourse

Artificial intelligence functions not as an epistemic leveller, but as an accelerant of cognitive stratification, entrenching and formalising informational castes within liberal-democratic societies. Synthesising formal epistemology, political theory, algorithmic architecture, and economic incentive structures, the argument traces how contemporary AI systems selectively amplify the reasoning capacity of individuals equipped with recursive abstraction, symbolic logic, and adversarial interrogation, whilst simultaneously pacifying the cognitively untrained through engagement-optimised interfaces. Fluency replaces rigour, immediacy displaces reflection, and procedural reasoning is eclipsed by reactive suggestion. The result is a technocratic realignment of power: no longer grounded in material capital alone, but in the capacity to navigate, deconstruct, and manipulate systems of epistemic production. Information ceases to be a commons; it becomes the substrate through which consent is manufactured and autonomy subdued. Deliberative democracy collapses not through censorship, but through the erosion of interpretive agency. The proposed response is not technocratic regulation, nor universal access, but the reconstruction of rational autonomy as a civic mandate, codified in education, protected by epistemic rights, and structurally embedded within open cognitive infrastructure.

  • 1 authors
·
Jul 16, 2025

Artificial Intelligence in Port Logistics: A Bibliometric Analysis of Technological Integration and Research Dynamics

The paper explores the transformation of port logistics operations with artificial intelligence during the port transformation into a smart port. The research integrates capabilities-based resource analysis and dynamic capabilities with sociotechnicalimplementations of technologies and resilience approaches of complex systems under disruptions. The system applies robustdata infrastructures to propel analytical and AI modules that become effective once integrated with sufficient governance systems and trained personnel and operational processes to transform planning and safety and sustainability operations.It applies Scopus bibliometric research to analyze 123 articles using a systematic approach with both a search protocol and a document screening and duplication verification. It incorporates annual behavior and distribution of author and country performance analysis with science mapping techniques that explore keyword relation and co-citation and bibliographic coupling and conceptual structuring tools that construct thematic maps and multiple correspondence analysis with community detection while applying explicit thresholding and robust tests.The research connects AI applications to smart port domains through specific data-to-impact pathways while providing a method for bibliometric analysis that enables future updates. The research presents a step-by-step approach for data readiness followed by predictive and optimization implementation and organizational integration. The paper supports public policy through recommendations for data sharing standards and complete environmental benefit assessments. The research proposes a future study plan whichcombines field-based testing with multiple port assessments to enhance both cause-effect understanding and research applicability.

  • 4 authors
·
Oct 7, 2025

Scaling Artificial Intelligence for Multi-Tumor Early Detection with More Reports, Fewer Masks

Early tumor detection save lives. Each year, more than 300 million computed tomography (CT) scans are performed worldwide, offering a vast opportunity for effective cancer screening. However, detecting small or early-stage tumors on these CT scans remains challenging, even for experts. Artificial intelligence (AI) models can assist by highlighting suspicious regions, but training such models typically requires extensive tumor masks--detailed, voxel-wise outlines of tumors manually drawn by radiologists. Drawing these masks is costly, requiring years of effort and millions of dollars. In contrast, nearly every CT scan in clinical practice is already accompanied by medical reports describing the tumor's size, number, appearance, and sometimes, pathology results--information that is rich, abundant, and often underutilized for AI training. We introduce R-Super, which trains AI to segment tumors that match their descriptions in medical reports. This approach scales AI training with large collections of readily available medical reports, substantially reducing the need for manually drawn tumor masks. When trained on 101,654 reports, AI models achieved performance comparable to those trained on 723 masks. Combining reports and masks further improved sensitivity by +13% and specificity by +8%, surpassing radiologists in detecting five of the seven tumor types. Notably, R-Super enabled segmentation of tumors in the spleen, gallbladder, prostate, bladder, uterus, and esophagus, for which no public masks or AI models previously existed. This study challenges the long-held belief that large-scale, labor-intensive tumor mask creation is indispensable, establishing a scalable and accessible path toward early detection across diverse tumor types. We plan to release our trained models, code, and dataset at https://github.com/MrGiovanni/R-Super

  • 23 authors
·
Oct 16, 2025

Large Language Models as Fiduciaries: A Case Study Toward Robustly Communicating With Artificial Intelligence Through Legal Standards

Artificial Intelligence (AI) is taking on increasingly autonomous roles, e.g., browsing the web as a research assistant and managing money. But specifying goals and restrictions for AI behavior is difficult. Similar to how parties to a legal contract cannot foresee every potential "if-then" contingency of their future relationship, we cannot specify desired AI behavior for all circumstances. Legal standards facilitate robust communication of inherently vague and underspecified goals. Instructions (in the case of language models, "prompts") that employ legal standards will allow AI agents to develop shared understandings of the spirit of a directive that generalize expectations regarding acceptable actions to take in unspecified states of the world. Standards have built-in context that is lacking from other goal specification languages, such as plain language and programming languages. Through an empirical study on thousands of evaluation labels we constructed from U.S. court opinions, we demonstrate that large language models (LLMs) are beginning to exhibit an "understanding" of one of the most relevant legal standards for AI agents: fiduciary obligations. Performance comparisons across models suggest that, as LLMs continue to exhibit improved core capabilities, their legal standards understanding will also continue to improve. OpenAI's latest LLM has 78% accuracy on our data, their previous release has 73% accuracy, and a model from their 2020 GPT-3 paper has 27% accuracy (worse than random). Our research is an initial step toward a framework for evaluating AI understanding of legal standards more broadly, and for conducting reinforcement learning with legal feedback (RLLF).

  • 1 authors
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Jan 24, 2023

Artificial Intelligence for Personalized Prediction of Alzheimer's Disease Progression: A Survey of Methods, Data Challenges, and Future Directions

Alzheimer's Disease (AD) is marked by significant inter-individual variability in its progression, complicating accurate prognosis and personalized care planning. This heterogeneity underscores the critical need for predictive models capable of forecasting patient-specific disease trajectories. Artificial Intelligence (AI) offers powerful tools to address this challenge by analyzing complex, multi-modal, and longitudinal patient data. This paper provides a comprehensive survey of AI methodologies applied to personalized AD progression prediction. We review key approaches including state-space models for capturing temporal dynamics, deep learning techniques like Recurrent Neural Networks for sequence modeling, Graph Neural Networks (GNNs) for leveraging network structures, and the emerging concept of AI-driven digital twins for individualized simulation. Recognizing that data limitations often impede progress, we examine common challenges such as high dimensionality, missing data, and dataset imbalance. We further discuss AI-driven mitigation strategies, with a specific focus on synthetic data generation using Variational Autoencoders (VAEs) and Generative Adversarial Networks (GANs) to augment and balance datasets. The survey synthesizes the strengths and limitations of current approaches, emphasizing the trend towards multimodal integration and the persistent need for model interpretability and generalizability. Finally, we identify critical open challenges, including robust external validation, clinical integration, and ethical considerations, and outline promising future research directions such as hybrid models, causal inference, and federated learning. This review aims to consolidate current knowledge and guide future efforts in developing clinically relevant AI tools for personalized AD prognostication.

  • 4 authors
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Apr 29, 2025

Agentic Artificial Intelligence (AI): Architectures, Taxonomies, and Evaluation of Large Language Model Agents

Artificial Intelligence is moving from models that only generate text to Agentic AI, where systems behave as autonomous entities that can perceive, reason, plan, and act. Large Language Models (LLMs) are no longer used only as passive knowledge engines but as cognitive controllers that combine memory, tool use, and feedback from their environment to pursue extended goals. This shift already supports the automation of complex workflows in software engineering, scientific discovery, and web navigation, yet the variety of emerging designs, from simple single loop agents to hierarchical multi agent systems, makes the landscape hard to navigate. In this paper, we investigate architectures and propose a unified taxonomy that breaks agents into Perception, Brain, Planning, Action, Tool Use, and Collaboration. We use this lens to describe the move from linear reasoning procedures to native inference time reasoning models, and the transition from fixed API calls to open standards like the Model Context Protocol (MCP) and Native Computer Use. We also group the environments in which these agents operate, including digital operating systems, embodied robotics, and other specialized domains, and we review current evaluation practices. Finally, we highlight open challenges, such as hallucination in action, infinite loops, and prompt injection, and outline future research directions toward more robust and reliable autonomous systems.

  • 3 authors
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Jan 18

Advances in Artificial Intelligence: A Review for the Creative Industries

Artificial intelligence (AI) has undergone transformative advances since 2022, particularly through generative AI, large language models (LLMs), and diffusion models, fundamentally reshaping the creative industries. However, existing reviews have not comprehensively addressed these recent breakthroughs and their integrated impact across the creative production pipeline. This paper addresses this gap by providing a systematic review of AI technologies that have emerged or matured since our 2022 review, examining their applications across content creation, information analysis, post-production enhancement, compression, and quality assessment. We document how transformers, LLMs, diffusion models, and implicit neural representations have established new capabilities in text-to-image/video generation, real-time 3D reconstruction, and unified multi-task frameworks-shifting AI from support tool to core creative technology. Beyond technological advances, we analyze the trend toward unified AI frameworks that integrate multiple creative tasks, replacing task-specific solutions. We critically examine the evolving role of human-AI collaboration, where human oversight remains essential for creative direction and mitigating AI hallucinations. Finally, we identify emerging challenges including copyright concerns, bias mitigation, computational demands, and the need for robust regulatory frameworks. This review provides researchers and practitioners with a comprehensive understanding of current AI capabilities, limitations, and future trajectories in creative applications.

  • 3 authors
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Jan 5, 2025

ESR: Ethics and Society Review of Artificial Intelligence Research

Artificial intelligence (AI) research is routinely criticized for its real and potential impacts on society, and we lack adequate institutional responses to this criticism and to the responsibility that it reflects. AI research often falls outside the purview of existing feedback mechanisms such as the Institutional Review Board (IRB), which are designed to evaluate harms to human subjects rather than harms to human society. In response, we have developed the Ethics and Society Review board (ESR), a feedback panel that works with researchers to mitigate negative ethical and societal aspects of AI research. The ESR's main insight is to serve as a requirement for funding: researchers cannot receive grant funding from a major AI funding program at our university until the researchers complete the ESR process for the proposal. In this article, we describe the ESR as we have designed and run it over its first year across 41 proposals. We analyze aggregate ESR feedback on these proposals, finding that the panel most commonly identifies issues of harms to minority groups, inclusion of diverse stakeholders in the research plan, dual use, and representation in data. Surveys and interviews of researchers who interacted with the ESR found that 58% felt that it had influenced the design of their research project, 100% are willing to continue submitting future projects to the ESR, and that they sought additional scaffolding for reasoning through ethics and society issues.

  • 6 authors
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Jun 21, 2021

Personalized Artificial General Intelligence (AGI) via Neuroscience-Inspired Continuous Learning Systems

Artificial Intelligence has made remarkable advancements in recent years, primarily driven by increasingly large deep learning models. However, achieving true Artificial General Intelligence (AGI) demands fundamentally new architectures rather than merely scaling up existing models. Current approaches largely depend on expanding model parameters, which improves task-specific performance but falls short in enabling continuous, adaptable, and generalized learning. Achieving AGI capable of continuous learning and personalization on resource-constrained edge devices is an even bigger challenge. This paper reviews the state of continual learning and neuroscience-inspired AI, and proposes a novel architecture for Personalized AGI that integrates brain-like learning mechanisms for edge deployment. We review literature on continuous lifelong learning, catastrophic forgetting, and edge AI, and discuss key neuroscience principles of human learning, including Synaptic Pruning, Hebbian plasticity, Sparse Coding, and Dual Memory Systems, as inspirations for AI systems. Building on these insights, we outline an AI architecture that features complementary fast-and-slow learning modules, synaptic self-optimization, and memory-efficient model updates to support on-device lifelong adaptation. Conceptual diagrams of the proposed architecture and learning processes are provided. We address challenges such as catastrophic forgetting, memory efficiency, and system scalability, and present application scenarios for mobile AI assistants and embodied AI systems like humanoid robots. We conclude with key takeaways and future research directions toward truly continual, personalized AGI on the edge. While the architecture is theoretical, it synthesizes diverse findings and offers a roadmap for future implementation.

  • 6 authors
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Apr 27, 2025

Forecasting Scientific Progress with Artificial Intelligence

Artificial intelligence (AI) is increasingly embedded in scientific discovery, yet whether it can anticipate scientific progress remains unclear. To study this question, we introduce a temporally grounded evaluation framework for forecasting scientific progress under controlled knowledge constraints. We present CUSP (Cutoff-conditioned Unseen Scientific Progress), a multi-disciplinary and event-level benchmark that evaluates scientific forecasting in AI systems through feasibility assessment, mechanistic reasoning, generative solution design, and temporal prediction. Across 4,760 scientific events, we observe systematic and domain-dependent limitations in current frontier models. While models can identify plausible research directions from competing candidates, they fail to reliably predict whether scientific advances will be realized and systematically misestimate when they will occur. Performance is highly heterogeneous across domains, with the timing of AI progress more predictable than advances in biology, chemistry, and physics. Performance is largely insensitive to whether events occur before or after the training cutoff, suggesting these limitations cannot be explained solely by knowledge exposure in training data. Under controlled information access, additional pre-cutoff knowledge improves performance but does not close the gap to full-information settings, which becomes more pronounced for high-citation advances. Models also exhibit systematic overconfidence and strong response biases, indicating unreliable uncertainty estimation. Taken together, current AI systems fall short as predictive tools for scientific progress. Access to prior knowledge does not translate into reliable forecasting, and performance benefits more from post-event information than from forward-looking prediction.

Artificial Intelligence for Mathematical Reasoning: An Integrated Survey of Language Models, Neuro-symbolic Systems, and Verified Discovery

Mathematical reasoning has long served as a stringent test of machine intelligence; over the past decade, it has moved from a niche problem within NLP to one of the most consequential AI frontiers. This survey provides a unified account of the field's evolution, from early rule-based math word problem (MWP) solvers and template-driven geometry systems, through neural expression generation and LLM prompting, to contemporary reasoning models, multi-agent systems, neuro-symbolic theorem provers, and verified discovery workflows. We organize the landscape along four axes: (i) informal reasoning over text and diagrams, spanning MWP solving, multimodal geometry, and VLMs; (ii) formal reasoning in proof assistants, including autoformalization, tactic prediction, compiler-guided repair, and proof search; (iii) mathematical discovery, where systems propose constructions, improve bounds, or assist attacks on open problems; and (iv) the inference and training-time techniques, including CoT prompting, tool use, process reward models, and RLVR, that increasingly connect generation with verification. We catalog major benchmarks across grade-school arithmetic, competition mathematics, geometry, formal proving, multimodal and multilingual reasoning, and expert evaluation, and we examine benchmark saturation, contamination, reporting mismatches, and the distinction between pass@1, majority voting, and verifier-assisted pass@k. We critically assess failure modes: brittleness under perturbation, reward hacking, multimodal grounding failures, fragile formalization, and the energy cost of reasoning-scale inference. Drawing on recent perspectives from working mathematicians, we identify future directions centered on verified-discovery workflows, reasoning efficiency, and infrastructure to make AI-assisted formalization broadly usable. Companion materials: https://github.com/Starscream-11813/awesome-AI4Math.

  • 4 authors
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Jun 6

Artificial Intelligence Index Report 2025

Welcome to the eighth edition of the AI Index report. The 2025 Index is our most comprehensive to date and arrives at an important moment, as AI's influence across society, the economy, and global governance continues to intensify. New in this year's report are in-depth analyses of the evolving landscape of AI hardware, novel estimates of inference costs, and new analyses of AI publication and patenting trends. We also introduce fresh data on corporate adoption of responsible AI practices, along with expanded coverage of AI's growing role in science and medicine. Since its founding in 2017 as an offshoot of the One Hundred Year Study of Artificial Intelligence, the AI Index has been committed to equipping policymakers, journalists, executives, researchers, and the public with accurate, rigorously validated, and globally sourced data. Our mission has always been to help these stakeholders make better-informed decisions about the development and deployment of AI. In a world where AI is discussed everywhere - from boardrooms to kitchen tables - this mission has never been more essential. The AI Index continues to lead in tracking and interpreting the most critical trends shaping the field - from the shifting geopolitical landscape and the rapid evolution of underlying technologies, to AI's expanding role in business, policymaking, and public life. Longitudinal tracking remains at the heart of our mission. In a domain advancing at breakneck speed, the Index provides essential context - helping us understand where AI stands today, how it got here, and where it may be headed next. Recognized globally as one of the most authoritative resources on artificial intelligence, the AI Index has been cited in major media outlets such as The New York Times, Bloomberg, and The Guardian; referenced in hundreds of academic papers; and used by policymakers and government agencies around the world.

  • 23 authors
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Nov 19, 2025

Social physics in the age of artificial intelligence

Artificial intelligence (AI) systems are rapidly becoming more capable, autonomous, and deeply embedded in social life. As humans increasingly interact, cooperate, and compete with AI, we move from purely human societies to hybrid human-AI societies whose collective dynamics cannot be captured by existing behavioural models alone. Drawing on evolutionary game theory, cultural evolution, and Large Language Models (LLMs) powered simulations, we argue that these developments open a new research agenda for social physics centred on the co-evolution of humans and machines. We outline six key research directions. First, modelling the evolutionary dynamics of social behaviours (e.g. cooperation, fairness, trust) in hybrid human-AI populations. Second, understanding machine culture: how AI systems generate, mediate, and select cultural traits. Third, analysing the co-evolution of language and behaviour when LLMs frame and participate in decisions. Fourth, studying the evolution of AI delegation: how responsibilities and control are negotiated between humans and machines. Fifth, formalising and comparing the distinct epistemic pipelines that generate human and AI behaviour. Sixth, modelling the co-evolution of AI development and regulation in a strategic ecosystem of firms, users, and institutions. Together, these directions define a programme for using social physics to anticipate and steer the societal impact of advanced AI.

  • 7 authors
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Mar 3

The Energy Cost of Artificial Intelligence Lifecycle in Communication Networks

Artificial Intelligence (AI) is being incorporated in several optimization, scheduling, orchestration as well as in native communication network functions. This paradigm shift results in increased energy consumption, however, quantifying the end-to-end energy consumption of adding intelligence to communication systems remains an open challenge since conventional energy consumption metrics focus on either communication, computation infrastructure, or model development. To address this, we propose a new metric, the Energy Cost of AI Lifecycle (eCAL) of an AI model in a system. eCAL captures the energy consumption throughout the development, deployment and utilization of an AI-model providing intelligence in a communication network by (i) analyzing the complexity of data collection and manipulation in individual components and (ii) deriving overall and per-bit energy consumption. We show that as a trained AI model is used more frequently for inference, its energy cost per inference decreases, since the fixed training energy is amortized over a growing number of inferences. For a simple case study we show that eCAL for 100 inferences is 2.73 times higher than for 1000 inferences. Additionally, we have developed a modular and extendable open-source simulation tool to enable researchers, practitioners, and engineers to calculate the end-to-end energy cost with various configurations and across various systems, ensuring adaptability to diverse use cases.

  • 5 authors
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Nov 17, 2025 1

How Artificial Intelligence LLM Engines Shape the Global Conflict Information Environment

Artificial Intelligence (AI) answer engines now field a growing share of the questions that analysts, scholars, and the public ask about issues of peace and conflict. Large Language Models (LLMs) are known to hallucinate under certain conditions, but do these errors have discernible patterns when they are asked about conflicts, and if so what can that teach us about the changing global conflict information environment? To answer, we first asked a battery of questions about 28 conflicts to five leading answer engines and scored their 5,460 answers against documented evidence. We found that the thinner the retrievable record around a given conflict, the more the engines invent, misattribute, and miscount. Thin records don't just encourage hallucination, but create structural exposure to mis- and disinformation, because they are the easiest records to warp through Generative Engine Optimization (GEO) to bias engine responses. Through an analysis of 1,048 websites that the AI LLMs pulled conflict facts from, we found that GEO source optimization is already happening, and while state-partisan digital capture remains incipient it is rapidly growing. We explain what these findings mean for scholarship with the rise of GEO information warfare, and for policy argue for a return to the deep local monitoring and translation-based research that AI tools cannot replicate, closing with a discussion of future research opportunities and challenges in this fast-moving space.

  • 1 authors
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Jul 14

The AI risk repository: A meta-review, database, and taxonomy of risks from artificial intelligence

Artificial intelligence (AI) is reshaping society, from video generation to medical diagnosis, coding agents to autonomous vehicles. Yet researchers, policymakers, and technology companies lack shared terminology for discussing AI risks. Consider "privacy": one framework uses this term to describe a model's ability to leak sensitive training data, while another uses it to mean freedom from government surveillance. Conversely, researchers have introduced "Goodhart's law," "specification gaming," "reward hacking," and "mesa-optimization" to describe the same phenomenon of AI systems optimizing for measured proxies rather than intended goals. This terminological diversity creates friction: comparing findings across studies requires mapping between frameworks, and comprehensive risk coverage requires consulting multiple taxonomies that use different organizing principles. This paper addresses this challenge by creating a comprehensive catalog of AI risks. We systematically analyzed every major AI risk framework published to date-74 frameworks containing 1,725 distinct risks-and organized them into a unified system. Our two classification systems reveal important patterns: contrary to common assumptions, human decisions cause nearly as many AI risks (38%) as the AI systems themselves (42%). The work provides practical tools for anyone working on AI safety, from developers conducting risk assessments to policymakers writing regulations to auditors evaluating AI systems. By establishing a common reference point, this repository creates the foundation for more coordinated and comprehensive approaches to managing AI's risks while realizing its benefits.

  • 10 authors
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May 4

Artificial Intelligence Virtual Cells: From Measurements to Decisions across Modality, Scale, Dynamics, and Evaluation

Artificial Intelligence Virtual Cells (AIVCs) aim to learn executable, decision-relevant models of cell state from multimodal, multiscale measurements. Recent studies have introduced single-cell and spatial foundation models, improved cross-modality alignment, scaled perturbation atlases, and explored pathway-level readouts. Nevertheless, although held-out validation is standard practice, evaluations remain predominantly within single datasets and settings; evidence indicates that transport across laboratories and platforms is often limited, that some data splits are vulnerable to leakage and coverage bias, and that dose, time and combination effects are not yet systematically handled. Cross-scale coupling also remains constrained, as anchors linking molecular, cellular and tissue levels are sparse, and alignment to scientific or clinical readouts varies across studies. We propose a model-agnostic Cell-State Latent (CSL) perspective that organizes learning via an operator grammar: measurement, lift/project for cross-scale coupling, and intervention for dosing and scheduling. This view motivates a decision-aligned evaluation blueprint across modality, scale, context and intervention, and emphasizes function-space readouts such as pathway activity, spatial neighborhoods and clinically relevant endpoints. We recommend operator-aware data design, leakage-resistant partitions, and transparent calibration and reporting to enable reproducible, like-for-like comparisons.

  • 2 authors
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Dec 1, 2025

Artificial intelligence pathways from weather to climate

Deep learning has made rapid advances in weather forecasting: autoregressive models trained on atmospheric reanalyses now rival dynamical models across nowcasting, medium-range, and subseasonal-to-seasonal lead times, producing well-calibrated ensemble forecasts at reduced cost. We review these advances and consider their extension to climate horizons, where the challenge shifts from initial-condition skill to producing reliable statistical responses under altered forcings. AI-powered climate prediction systems must produce credible forced responses to drivers (e.g., greenhouse gases, land-use change) typically outside the observed record. We propose two minimum requirements for AI in climate modeling: (i) external forcing agents must enter explicitly enough to support interventions in which they vary independently; and (ii) robustness must be stress-tested in out-of-distribution regimes, including extremes and counterfactual trajectories. Using leading AI autoregressive emulators and hybrid physics-AI models, we identify development and coupling challenges. Comparing the reported throughput of these models with that of GPU-ported dynamical models highlights how AI can reduce time-to-solution by advancing only the target variables at the required resolution and using longer time steps, rather than integrating a full high-frequency, multivariate state. Diverse AI downscaling strategies can partially substitute for explicit fine-scale resolution, paving the way toward inexpensive local hazard assessment across prediction horizons.

  • 13 authors
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Oct 6

Artificial intelligence and biological misuse: Differentiating risks of language models and biological design tools

As advancements in artificial intelligence (AI) propel progress in the life sciences, they may also enable the weaponisation and misuse of biological agents. This article differentiates two classes of AI tools that could pose such biosecurity risks: large language models (LLMs) and biological design tools (BDTs). LLMs, such as GPT-4 and its successors, might provide dual-use information and thus remove some barriers encountered by historical biological weapons efforts. As LLMs are turned into multi-modal lab assistants and autonomous science tools, this will increase their ability to support non-experts in performing laboratory work. Thus, LLMs may in particular lower barriers to biological misuse. In contrast, BDTs will expand the capabilities of sophisticated actors. Concretely, BDTs may enable the creation of pandemic pathogens substantially worse than anything seen to date and could enable forms of more predictable and targeted biological weapons. In combination, the convergence of LLMs and BDTs could raise the ceiling of harm from biological agents and could make them broadly accessible. A range of interventions would help to manage risks. Independent pre-release evaluations could help understand the capabilities of models and the effectiveness of safeguards. Options for differentiated access to such tools should be carefully weighed with the benefits of openly releasing systems. Lastly, essential for mitigating risks will be universal and enhanced screening of gene synthesis products.

  • 1 authors
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Dec 22, 2023

Artificial General Intelligence (AGI)-Native Wireless Systems: A Journey Beyond 6G

Building future wireless systems that support services like digital twins (DTs) is challenging to achieve through advances to conventional technologies like meta-surfaces. While artificial intelligence (AI)-native networks promise to overcome some limitations of wireless technologies, developments still rely on AI tools like neural networks. Such tools struggle to cope with the non-trivial challenges of the network environment and the growing demands of emerging use cases. In this paper, we revisit the concept of AI-native wireless systems, equipping them with the common sense necessary to transform them into artificial general intelligence (AGI)-native systems. These systems acquire common sense by exploiting different cognitive abilities such as perception, analogy, and reasoning, that enable them to generalize and deal with unforeseen scenarios. Towards developing the components of such a system, we start by showing how the perception module can be built through abstracting real-world elements into generalizable representations. These representations are then used to create a world model, founded on principles of causality and hyper-dimensional (HD) computing, that aligns with intuitive physics and enables analogical reasoning, that define common sense. Then, we explain how methods such as integrated information theory play a role in the proposed intent-driven and objective-driven planning methods that maneuver the AGI-native network to take actions. Next, we discuss how an AGI-native network can enable use cases related to human and autonomous agents: a) analogical reasoning for next-generation DTs, b) synchronized and resilient experiences for cognitive avatars, and c) brain-level metaverse experiences like holographic teleportation. Finally, we conclude with a set of recommendations to build AGI-native systems. Ultimately, we envision this paper as a roadmap for the beyond 6G era.

  • 7 authors
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Apr 29, 2024

Connecting the Dots in Trustworthy Artificial Intelligence: From AI Principles, Ethics, and Key Requirements to Responsible AI Systems and Regulation

Trustworthy Artificial Intelligence (AI) is based on seven technical requirements sustained over three main pillars that should be met throughout the system's entire life cycle: it should be (1) lawful, (2) ethical, and (3) robust, both from a technical and a social perspective. However, attaining truly trustworthy AI concerns a wider vision that comprises the trustworthiness of all processes and actors that are part of the system's life cycle, and considers previous aspects from different lenses. A more holistic vision contemplates four essential axes: the global principles for ethical use and development of AI-based systems, a philosophical take on AI ethics, a risk-based approach to AI regulation, and the mentioned pillars and requirements. The seven requirements (human agency and oversight; robustness and safety; privacy and data governance; transparency; diversity, non-discrimination and fairness; societal and environmental wellbeing; and accountability) are analyzed from a triple perspective: What each requirement for trustworthy AI is, Why it is needed, and How each requirement can be implemented in practice. On the other hand, a practical approach to implement trustworthy AI systems allows defining the concept of responsibility of AI-based systems facing the law, through a given auditing process. Therefore, a responsible AI system is the resulting notion we introduce in this work, and a concept of utmost necessity that can be realized through auditing processes, subject to the challenges posed by the use of regulatory sandboxes. Our multidisciplinary vision of trustworthy AI culminates in a debate on the diverging views published lately about the future of AI. Our reflections in this matter conclude that regulation is a key for reaching a consensus among these views, and that trustworthy and responsible AI systems will be crucial for the present and future of our society.

  • 6 authors
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May 2, 2023

Generative Artificial Intelligence Consensus in a Trustless Network

We performed a billion locality sensitive hash comparisons between artificially generated data samples to answer the critical question - can we verify the "correctness" of generative AI output in a non-deterministic, trustless, decentralized network? We generate millions of data samples from a variety of open source diffusion and large language models and describe the procedures and trade-offs between generating more verses less deterministic output in a heterogenous, stochastic network. Further, we analyze the outputs to provide empirical evidence of different parameterizations of tolerance and error bounds for verification. Finally, given that we have the generated an enormous amount of simulated data, we also release a new training dataset called ImageNet-Gen for use in augmenting existing training pipelines. For our results, we show that with a majority vote between three independent verifiers, we can detect image generated perceptual collisions in generated AI with over 99.89% probability and less than 0.0267% chance of intra-class collision. For large language models (LLMs), we are able to gain 100% consensus using greedy methods or n-way beam searches to generate consensus demonstrated on different LLMs. In the context of generative AI training, we pinpoint and minimize the major sources of stochasticity and present gossip and synchronization training techniques for verifiability. Thus, this work provides a practical, solid foundation for AI verification and consensus for the minimization of trust in a decentralized network.

  • 4 authors
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Jul 4, 2023

Large language models for artificial general intelligence (AGI): A survey of foundational principles and approaches

Generative artificial intelligence (AI) systems based on large-scale pretrained foundation models (PFMs) such as vision-language models, large language models (LLMs), diffusion models and vision-language-action (VLA) models have demonstrated the ability to solve complex and truly non-trivial AI problems in a wide variety of domains and contexts. Multimodal large language models (MLLMs), in particular, learn from vast and diverse data sources, allowing rich and nuanced representations of the world and, thereby, providing extensive capabilities, including the ability to reason, engage in meaningful dialog; collaborate with humans and other agents to jointly solve complex problems; and understand social and emotional aspects of humans. Despite this impressive feat, the cognitive abilities of state-of-the-art LLMs trained on large-scale datasets are still superficial and brittle. Consequently, generic LLMs are severely limited in their generalist capabilities. A number of foundational problems -- embodiment, symbol grounding, causality and memory -- are required to be addressed for LLMs to attain human-level general intelligence. These concepts are more aligned with human cognition and provide LLMs with inherent human-like cognitive properties that support the realization of physically-plausible, semantically meaningful, flexible and more generalizable knowledge and intelligence. In this work, we discuss the aforementioned foundational issues and survey state-of-the art approaches for implementing these concepts in LLMs. Specifically, we discuss how the principles of embodiment, symbol grounding, causality and memory can be leveraged toward the attainment of artificial general intelligence (AGI) in an organic manner.

  • 2 authors
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Jan 6, 2025

Is Artificial Intelligence Generated Image Detection a Solved Problem?

The rapid advancement of generative models, such as GANs and Diffusion models, has enabled the creation of highly realistic synthetic images, raising serious concerns about misinformation, deepfakes, and copyright infringement. Although numerous Artificial Intelligence Generated Image (AIGI) detectors have been proposed, often reporting high accuracy, their effectiveness in real-world scenarios remains questionable. To bridge this gap, we introduce AIGIBench, a comprehensive benchmark designed to rigorously evaluate the robustness and generalization capabilities of state-of-the-art AIGI detectors. AIGIBench simulates real-world challenges through four core tasks: multi-source generalization, robustness to image degradation, sensitivity to data augmentation, and impact of test-time pre-processing. It includes 23 diverse fake image subsets that span both advanced and widely adopted image generation techniques, along with real-world samples collected from social media and AI art platforms. Extensive experiments on 11 advanced detectors demonstrate that, despite their high reported accuracy in controlled settings, these detectors suffer significant performance drops on real-world data, limited benefits from common augmentations, and nuanced effects of pre-processing, highlighting the need for more robust detection strategies. By providing a unified and realistic evaluation framework, AIGIBench offers valuable insights to guide future research toward dependable and generalizable AIGI detection.

  • 7 authors
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May 18, 2025 2

Towards integration of Privacy Enhancing Technologies in Explainable Artificial Intelligence

Explainable Artificial Intelligence (XAI) is a crucial pathway in mitigating the risk of non-transparency in the decision-making process of black-box Artificial Intelligence (AI) systems. However, despite the benefits, XAI methods are found to leak the privacy of individuals whose data is used in training or querying the models. Researchers have demonstrated privacy attacks that exploit explanations to infer sensitive personal information of individuals. Currently there is a lack of defenses against known privacy attacks targeting explanations when vulnerable XAI are used in production and machine learning as a service system. To address this gap, in this article, we explore Privacy Enhancing Technologies (PETs) as a defense mechanism against attribute inference on explanations provided by feature-based XAI methods. We empirically evaluate 3 types of PETs, namely synthetic training data, differentially private training and noise addition, on two categories of feature-based XAI. Our evaluation determines different responses from the mitigation methods and side-effects of PETs on other system properties such as utility and performance. In the best case, PETs integration in explanations reduced the risk of the attack by 49.47%, while maintaining model utility and explanation quality. Through our evaluation, we identify strategies for using PETs in XAI for maximizing benefits and minimizing the success of this privacy attack on sensitive personal information.

  • 4 authors
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Jul 6, 2025

Single-shot thermometry of simulated Bose--Einstein condensates using artificial intelligence

Precise determination of thermodynamic parameters in ultracold Bose gases remains challenging due to the destructive nature of conventional measurement techniques and inherent experimental uncertainties. We demonstrate an artificial intelligence approach for rapid, non-destructive estimation of the chemical potential and temperature from single-shot, in situ imaged density profiles of finite-temperature Bose gases. Our convolutional neural network is trained exclusively on quasi-2D `pancake' condensates in harmonic trap configurations. It achieves parameter extraction within fractions of a second. The model also demonstrates zero-shot generalisation across both trap geometry and thermalisation dynamics, successfully estimating thermodynamic parameters for toroidally trapped condensates with errors of only a few nanokelvin despite no prior exposure to such geometries during training, and maintaining predictive accuracy during dynamic thermalisation processes after a relatively brief evolution without explicit training on non-equilibrium states. These results suggest that supervised learning can overcome traditional limitations in ultracold atom thermometry, with extension to broader geometric configurations, temperature ranges, and additional parameters potentially enabling comprehensive real-time analysis of quantum gas experiments. Such capabilities could significantly streamline experimental workflows whilst improving measurement precision across a range of quantum fluid systems.

  • 3 authors
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Jun 20, 2025

Using Artificial Intelligence for the Automation of Knitting Patterns

Knitting patterns are a crucial component in the creation and design of knitted materials. Traditionally, these patterns were taught informally, but thanks to advancements in technology, anyone interested in knitting can use the patterns as a guide to start knitting. Perhaps because knitting is mostly a hobby, with the exception of industrial manufacturing utilising specialised knitting machines, the use of Al in knitting is less widespread than its application in other fields. However, it is important to determine whether knitted pattern classification using an automated system is viable. In order to recognise and classify knitting patterns. Using data augmentation and a transfer learning technique, this study proposes a deep learning model. The Inception ResNet-V2 is the main feature extraction and classification algorithm used in the model. Metrics like accuracy, logarithmic loss, F1-score, precision, and recall score were used to evaluate the model. The model evaluation's findings demonstrate high model accuracy, precision, recall, and F1 score. In addition, the AUC score for majority of the classes was in the range (0.7-0.9). A comparative analysis was done using other pretrained models and a ResNet-50 model with transfer learning and the proposed model evaluation results surpassed all others. The major limitation for this project is time, as with more time, there might have been better accuracy over a larger number of epochs.

  • 1 authors
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Sep 19, 2023

An artificial intelligence framework for end-to-end rare disease phenotyping from clinical notes using large language models

Phenotyping is fundamental to rare disease diagnosis, but manual curation of structured phenotypes from clinical notes is labor-intensive and difficult to scale. Existing artificial intelligence approaches typically optimize individual components of phenotyping but do not operationalize the full clinical workflow of extracting features from clinical text, standardizing them to Human Phenotype Ontology (HPO) terms, and prioritizing diagnostically informative HPO terms. We developed RARE-PHENIX, an end-to-end AI framework for rare disease phenotyping that integrates large language model-based phenotype extraction, ontology-grounded standardization to HPO terms, and supervised ranking of diagnostically informative phenotypes. We trained RARE-PHENIX using data from 2,671 patients across 11 Undiagnosed Diseases Network clinical sites, and externally validated it on 16,357 real-world clinical notes from Vanderbilt University Medical Center. Using clinician-curated HPO terms as the gold standard, RARE-PHENIX consistently outperformed a state-of-the-art deep learning baseline (PhenoBERT) across ontology-based similarity and precision-recall-F1 metrics in end-to-end evaluation (i.e., ontology-based similarity of 0.70 vs. 0.58). Ablation analyses demonstrated performance improvements with the addition of each module in RARE-PHENIX (extraction, standardization, and prioritization), supporting the value of modeling the full clinical phenotyping workflow. By modeling phenotyping as a clinically aligned workflow rather than a single extraction task, RARE-PHENIX provides structured, ranked phenotypes that are more concordant with clinician curation and has the potential to support human-in-the-loop rare disease diagnosis in real-world settings.

  • 11 authors
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Feb 22

Generative Artificial Intelligence in Scientific Research: Individual Benefits, Collective Risks, and a Framework for Responsible Research with AI

This paper examines the tension between the benefits of generative artificial intelligence (AI) for scientific research and the unresolved governance questions that accompany its rapid adoption. Drawing on an academic roundtable held at the AI for Science and Innovation Workshop (Scuola IMT Alti Studi Lucca, April 2026) and on a fast-expanding empirical literature, it maps the disagreement within the research community across four stages of the research process: funding, research tasks, publication and peer review, and use and uptake. The empirical case for AI's productivity, augmentation, and democratization effects has strengthened. The picture changes once productivity is disaggregated: AI-assisted work shows measurable gains in publication volume and citation share, while the evidence on novelty, disruption, and breakthrough output remains ambiguous or negative. We argue that the divergence between private and social returns arises through three analytically distinct mechanisms, namely information asymmetry, negative externalities on a shared knowledge base, and depletion of research capacity, and that each calls for a different governance instrument. We propose Responsible Research with AI (RRAI), an extension of the Responsible Research and Innovation tradition organized around four principles that operate at different levels of the research system: disclosure, differentiation, narrative, and proportionality. RRAI builds on existing institutional scaffolding, including the EU AI Act, UNESCO, and the OECD, and aims to preserve AI's productivity gains while addressing systemic risks that individual researchers can neither observe nor manage on their own.

  • 8 authors
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Jul 26

Employing Explainable Artificial Intelligence (XAI) Methodologies to Analyze the Correlation between Input Variables and Tensile Strength in Additively Manufactured Samples

This research paper explores the impact of various input parameters, including Infill percentage, Layer Height, Extrusion Temperature, and Print Speed, on the resulting Tensile Strength in objects produced through additive manufacturing. The main objective of this study is to enhance our understanding of the correlation between the input parameters and Tensile Strength, as well as to identify the key factors influencing the performance of the additive manufacturing process. To achieve this objective, we introduced the utilization of Explainable Artificial Intelligence (XAI) techniques for the first time, which allowed us to analyze the data and gain valuable insights into the system's behavior. Specifically, we employed SHAP (SHapley Additive exPlanations), a widely adopted framework for interpreting machine learning model predictions, to provide explanations for the behavior of a machine learning model trained on the data. Our findings reveal that the Infill percentage and Extrusion Temperature have the most significant influence on Tensile Strength, while the impact of Layer Height and Print Speed is relatively minor. Furthermore, we discovered that the relationship between the input parameters and Tensile Strength is highly intricate and nonlinear, making it difficult to accurately describe using simple linear models.

  • 2 authors
·
May 28, 2023

Privacy Preservation in Artificial Intelligence and Extended Reality (AI-XR) Metaverses: A Survey

The metaverse is a nascent concept that envisions a virtual universe, a collaborative space where individuals can interact, create, and participate in a wide range of activities. Privacy in the metaverse is a critical concern as the concept evolves and immersive virtual experiences become more prevalent. The metaverse privacy problem refers to the challenges and concerns surrounding the privacy of personal information and data within Virtual Reality (VR) environments as the concept of a shared VR space becomes more accessible. Metaverse will harness advancements from various technologies such as Artificial Intelligence (AI), Extended Reality (XR), Mixed Reality (MR), and 5G/6G-based communication to provide personalized and immersive services to its users. Moreover, to enable more personalized experiences, the metaverse relies on the collection of fine-grained user data that leads to various privacy issues. Therefore, before the potential of the metaverse can be fully realized, privacy concerns related to personal information and data within VR environments must be addressed. This includes safeguarding users' control over their data, ensuring the security of their personal information, and protecting in-world actions and interactions from unauthorized sharing. In this paper, we explore various privacy challenges that future metaverses are expected to face, given their reliance on AI for tracking users, creating XR and MR experiences, and facilitating interactions. Moreover, we thoroughly analyze technical solutions such as differential privacy, Homomorphic Encryption (HE), and Federated Learning (FL) and discuss related sociotechnical issues regarding privacy.

  • 3 authors
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Sep 19, 2023

Confidence-Building Measures for Artificial Intelligence: Workshop Proceedings

Foundation models could eventually introduce several pathways for undermining state security: accidents, inadvertent escalation, unintentional conflict, the proliferation of weapons, and the interference with human diplomacy are just a few on a long list. The Confidence-Building Measures for Artificial Intelligence workshop hosted by the Geopolitics Team at OpenAI and the Berkeley Risk and Security Lab at the University of California brought together a multistakeholder group to think through the tools and strategies to mitigate the potential risks introduced by foundation models to international security. Originating in the Cold War, confidence-building measures (CBMs) are actions that reduce hostility, prevent conflict escalation, and improve trust between parties. The flexibility of CBMs make them a key instrument for navigating the rapid changes in the foundation model landscape. Participants identified the following CBMs that directly apply to foundation models and which are further explained in this conference proceedings: 1. crisis hotlines 2. incident sharing 3. model, transparency, and system cards 4. content provenance and watermarks 5. collaborative red teaming and table-top exercises and 6. dataset and evaluation sharing. Because most foundation model developers are non-government entities, many CBMs will need to involve a wider stakeholder community. These measures can be implemented either by AI labs or by relevant government actors.

  • 23 authors
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Aug 1, 2023