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Oct 16

Pose as Clinical Prior: Learning Dual Representations for Scoliosis Screening

Recent AI-based scoliosis screening methods primarily rely on large-scale silhouette datasets, often neglecting clinically relevant postural asymmetries-key indicators in traditional screening. In contrast, pose data provide an intuitive skeletal representation, enhancing clinical interpretability across various medical applications. However, pose-based scoliosis screening remains underexplored due to two main challenges: (1) the scarcity of large-scale, annotated pose datasets; and (2) the discrete and noise-sensitive nature of raw pose coordinates, which hinders the modeling of subtle asymmetries. To address these limitations, we introduce Scoliosis1K-Pose, a 2D human pose annotation set that extends the original Scoliosis1K dataset, comprising 447,900 frames of 2D keypoints from 1,050 adolescents. Building on this dataset, we introduce the Dual Representation Framework (DRF), which integrates a continuous skeleton map to preserve spatial structure with a discrete Postural Asymmetry Vector (PAV) that encodes clinically relevant asymmetry descriptors. A novel PAV-Guided Attention (PGA) module further uses the PAV as clinical prior to direct feature extraction from the skeleton map, focusing on clinically meaningful asymmetries. Extensive experiments demonstrate that DRF achieves state-of-the-art performance. Visualizations further confirm that the model leverages clinical asymmetry cues to guide feature extraction and promote synergy between its dual representations. The dataset and code are publicly available at https://zhouzi180.github.io/Scoliosis1K/.

  • 6 authors
·
Aug 31, 2025

Improving equilibrium propagation without weight symmetry through Jacobian homeostasis

Equilibrium propagation (EP) is a compelling alternative to the backpropagation of error algorithm (BP) for computing gradients of neural networks on biological or analog neuromorphic substrates. Still, the algorithm requires weight symmetry and infinitesimal equilibrium perturbations, i.e., nudges, to estimate unbiased gradients efficiently. Both requirements are challenging to implement in physical systems. Yet, whether and how weight asymmetry affects its applicability is unknown because, in practice, it may be masked by biases introduced through the finite nudge. To address this question, we study generalized EP, which can be formulated without weight symmetry, and analytically isolate the two sources of bias. For complex-differentiable non-symmetric networks, we show that the finite nudge does not pose a problem, as exact derivatives can still be estimated via a Cauchy integral. In contrast, weight asymmetry introduces bias resulting in low task performance due to poor alignment of EP's neuronal error vectors compared to BP. To mitigate this issue, we present a new homeostatic objective that directly penalizes functional asymmetries of the Jacobian at the network's fixed point. This homeostatic objective dramatically improves the network's ability to solve complex tasks such as ImageNet 32x32. Our results lay the theoretical groundwork for studying and mitigating the adverse effects of imperfections of physical networks on learning algorithms that rely on the substrate's relaxation dynamics.

  • 2 authors
·
Sep 5, 2023

VisionHOPE: Visual Backbones as Self-Modifying Learning Systems

Visual backbones have evolved from Convolutional Neural Networks (CNNs) with local aggregation to Vision Transformers (ViTs) with global interactions, State-Space Models (SSMs) with input-dependent state transitions, and Test-Time Training (TTT) layers that adapt an inner learner while processing an image. Across this progression, visual computation has become increasingly adaptive to each input, yet the rules governing that adaptation remain largely prescribed by the trained backbone. We introduce VisionHOPE, the first generic visual backbone formulated as a self-modifying learning system, in which what the model remembers and how it learns co-evolve within an image. Building on the self-referential construction of Nested Learning (NL), VisionHOPE realizes this co-evolution through five coupled memories that store content, generate key and value representations, and govern learning rate and retention. These memories evolve jointly as visual context accumulates along each scan. However, directly applying the unconstrained self-referential update to a visual backbone leads to instability. We therefore derive a stability-matched step-size control scheme that combines a soft cap on self-referential injection with a spectral clamp on the retained memory transition, and prove that the resulting memory dynamics are non-expansive along each scan. For two-dimensional feature maps, we adapt NL's chunk formulation by aligning chunks with image rows and columns across four directional scans. The proposed VisionHOPE achieves competitive results on ImageNet-1K, COCO, and ADE20K, establishing self-modifying learning systems as a practical foundation for general-purpose visual backbones. The code is available at https://github.com/PSRben/VisionHOPE.

Efficient and Effective Adaptation of Multimodal Foundation Models in Sequential Recommendation

Multimodal foundation models (MFMs) have revolutionized sequential recommender systems through advanced representation learning. While Parameter-efficient Fine-tuning (PEFT) is commonly used to adapt these models, studies often prioritize parameter efficiency, neglecting GPU memory and training speed. To address this, we introduced the IISAN framework, significantly enhancing efficiency. However, IISAN was limited to symmetrical MFMs and identical text and image encoders, preventing the use of state-of-the-art Large Language Models. To overcome this, we developed IISAN-Versa, a versatile plug-and-play architecture compatible with both symmetrical and asymmetrical MFMs. IISAN-Versa employs a Decoupled PEFT structure and utilizes both intra- and inter-modal adaptation. It effectively handles asymmetry through a simple yet effective combination of group layer-dropping and dimension transformation alignment. Our research demonstrates that IISAN-Versa effectively adapts large text encoders, and we further identify a scaling effect where larger encoders generally perform better. IISAN-Versa also demonstrates strong versatility in our defined multimodal scenarios, which include raw titles and captions generated from images and videos. Additionally, IISAN-Versa achieved state-of-the-art performance on the Microlens public benchmark. We release our code at https://github.com/GAIR-Lab/IISAN.

  • 8 authors
·
Nov 5, 2024

Homogenization framework for rigid and non-rigid foldable origami metamaterials

Origami metamaterials typically consist of folded sheets with periodic patterns, conferring them with remarkable mechanical properties. In the context of Continuum Mechanics, the majority of existing predictive methods are mechanism analogs which favor rigid folding and panel bending. While effective in predicting primary deformation modes, existing methods fall short in capturing the full spectrum of deformation of non-rigid foldable origami, such as the emergence of curvature along straight creases, local strain at vertices and warpage in panels. To fully capture the entire deformation spectrum and enhance the accuracy of existing methods, this paper introduces a homogenization framework for origami metamaterials where the faces are modeled as plate elements. Both asymptotic and energy-based homogenization methods are formulated and implemented. As a representative crease pattern, we examine the Miura origami sheet homogenized as an equivalent Kirchhoff-Love plate. The results reveal that certain effective elastic properties are nonlinearly related to both the initial fold angle and the crease stiffness. When benchmarked with results from fully resolved simulations, our framework yields errors up to 12.9\%, while existing models, including the bar-and-hinge model and the rigid-panel model, show up to 161\% error. The differences in errors are associated with the complex modes of crease and panel deformation in non-rigid origami, unexplored by the existing models. This work demonstrates a precise and efficient continuum framework for origami metamaterials as an effective strategy for predicting their elastic properties, understanding their mechanics, and designing their functionalities.

  • 4 authors
·
Aug 22, 2025

Fusion Complexity Inversion: Why Simpler Cross View Modules Outperform SSMs and Cross View Attention Transformers for Pasture Biomass Regression

Accurate estimation of pasture biomass from agricultural imagery is critical for sustainable livestock management, yet existing methods are limited by the small, imbalanced, and sparsely annotated datasets typical of real world monitoring. In this study, adaptation of vision foundation models to agricultural regression is systematically evaluated on the CSIRO Pasture Biomass benchmark, a 357 image dual view dataset with laboratory validated, component wise ground truth for five biomass targets, through 17 configurations spanning four backbones (EfficientNet-B3 to DINOv3-ViT-L), five cross view fusion mechanisms, and a 4x2 metadata factorial. A counterintuitive principle, termed "fusion complexity inversion", is uncovered: on scarce agricultural data, a two layer gated depthwise convolution (R^2 = 0.903) outperforms cross view attention transformers (0.833), bidirectional SSMs (0.819), and full Mamba (0.793, below the no fusion baseline). Backbone pretraining scale is found to monotonically dominate all architectural choices, with the DINOv2 -> DINOv3 upgrade alone yielding +5.0 R^2 points. Training only metadata (species, state, and NDVI) is shown to create a universal ceiling at R^2 ~ 0.829, collapsing an 8.4 point fusion spread to 0.1 points. Actionable guidelines for sparse agricultural benchmarks are established: backbone quality should be prioritized over fusion complexity, local modules preferred over global alternatives, and features unavailable at inference excluded.

  • 1 authors
·
Apr 22

With Great Backbones Comes Great Adversarial Transferability

Advances in self-supervised learning (SSL) for machine vision have improved representation robustness and model performance, giving rise to pre-trained backbones like ResNet and ViT models tuned with SSL methods such as SimCLR. Due to the computational and data demands of pre-training, the utilization of such backbones becomes a strenuous necessity. However, employing these backbones may inherit vulnerabilities to adversarial attacks. While adversarial robustness has been studied under white-box and black-box settings, the robustness of models tuned on pre-trained backbones remains largely unexplored. Additionally, the role of tuning meta-information in mitigating exploitation risks is unclear. This work systematically evaluates the adversarial robustness of such models across 20,000 combinations of tuning meta-information, including fine-tuning techniques, backbone families, datasets, and attack types. We propose using proxy models to transfer attacks, simulating varying levels of target knowledge by fine-tuning these proxies with diverse configurations. Our findings reveal that proxy-based attacks approach the effectiveness of white-box methods, even with minimal tuning knowledge. We also introduce a naive "backbone attack," leveraging only the backbone to generate adversarial samples, which outperforms black-box attacks and rivals white-box methods, highlighting critical risks in model-sharing practices. Finally, our ablations reveal how increasing tuning meta-information impacts attack transferability, measuring each meta-information combination.

  • 7 authors
·
Jan 20, 2025

FPicker: Topology-Guided Evolution for Filament Tracing in Low-SNR Microscopy

Automating filament tracing in Cryo-Electron Microscopy (Cryo-EM) is essential for 3D helical reconstruction but challenged by intersecting topologies and extremely low Signal-to-Noise Ratios (SNR = σ_s^2/σ_n^2 < 0.1 or -10 dB). Existing paradigms fail: pixel-wise segmenters suffer from severe topological fracturing, box-based detectors face ghost center drift, sequential trackers derail due to error accumulation, and traditional active contours collapse under artificial closed-curve constraints. To resolve these bottlenecks, we present FPicker, the first topology-guided framework reconciling these incompatibilities. It unifies perception via a center-endpoint representation and an open-curve evolution module to explicitly model non-cyclic connectivity. On simulated benchmarks, FPicker outperforms top baselines by over 40% relative gain in mean spatio-angular precision (mSAP) and reduces topological gap rates by over 60% under extreme noise (-20 dB). By learning intrinsic physical geometry rather than local texture, FPicker demonstrates strong potential as a resilient geometric backbone. Its zero-shot performance on the real-world EMPIAR dataset exhibits robust topological resistance, achieving a state-of-the-art 82.9\% mSAP upon fine-tuning. Our results also suggest modeling physical priors is a highly robust path toward bridging the sim-to-real gap in signal-starved scientific imaging. The code is publicly available at: https://github.com/tomzhaosky/FPicker.

  • 3 authors
·
Sep 7

Magic sizes enable minimal-complexity, high-fidelity assembly of programmable shells

Recent advances in synthetic methods enable designing subunits that self-assemble into structures with well-defined sizes and architectures, but yields are frequently suppressed by the formation of off-target metastable structures. Increasing the complexity (number of distinct inter-subunit interaction types) can inhibit off-target structures, but leads to slower kinetics and higher synthesis costs. Here, we use icosahedral shells formed of programmable triangular subunits as a model system, and identify design principles that produce the highest target yield at the lowest complexity. We use a symmetry-based construction to create a range of design complexities, starting from the maximal symmetry Caspar-Klug assembly up to the fully addressable, zero-symmetry assembly. Kinetic Monte Carlo simulations reveal that the most prominent defects leading to off-target assemblies are a class of disclinations. We derive symmetry-based rules for identifying the optimal (lowest-complexity, highest-symmetry) design that inhibits these disclinations, leading to robust, high-fidelity assembly of targets with arbitrarily large sizes. Optimal complexity varies non-monotonically with target size, with `magic' sizes appearing for high-symmetry designs in which symmetry axes do not intersect vertices of the triangular net. The optimal designs at magic sizes require 12 times fewer inequivalent interaction-types than the (minimal symmetry) fully addressable construction.

  • 6 authors
·
Nov 6, 2024

SymTRELLIS: Symmetry-Enforced Voxel Latents for 3D Generation

Single-view 3D generative models have achieved impressive visual quality, yet they are not designed to satisfy structural or functional requirements, and in practice, often fall short. Symmetry is one such requirement: violations, even subtle ones, on symmetry can render a model physically unusable. We present SymTRELLIS, a method that enforces arbitrary finite point group symmetries (rotational, reflectional, and polyhedral) during the flow-based 3D generation of TRELLIS.2, without retraining the underlying VAE or flow model. Our key idea is to approximate the latent-space action of spatial transformations as a learned linear operator on voxel latents, implemented as a lightweight spatial-transform latent mapper trained on generic, non-symmetric 3D data. At generation time, we enforce symmetry by averaging predicted flow velocities across all symmetry-equivalent transformations at each ODE step, a process we call velocity symmetrization. The symmetry specification can be estimated automatically from an initial TRELLIS.2 generation or supplied by the user, enabling deliberate fold manipulation beyond what the input image suggests. On a curated benchmark of 266 strictly symmetric objects spanning 2- to 20-fold rotations and polyhedral symmetry groups, SymTRELLIS substantially reduces all symmetry error metrics compared to TRELLIS.2, Hunyuan3D-2.1, and TripoSG, while maintaining reconstruction accuracy comparable to the base model.

symtrellis SymTRELLIS
·
Jun 1

Φeat: Physically-Grounded Feature Representation

Foundation models have emerged as effective backbones for many vision tasks. However, current self-supervised features entangle high-level semantics with low-level physical factors, such as geometry and illumination, hindering their use in tasks requiring explicit physical reasoning. In this paper, we introduce Φeat, a novel physically-grounded visual backbone that encourages a representation sensitive to material identity, including reflectance cues and geometric mesostructure. Our key idea is to employ a pretraining strategy that contrasts spatial crops and physical augmentations of the same material under varying shapes and lighting conditions. While similar data have been used in high-end supervised tasks such as intrinsic decomposition or material estimation, we demonstrate that a pure self-supervised training strategy, without explicit labels, already provides a strong prior for tasks requiring robust features invariant to external physical factors. We evaluate the learned representations through feature similarity analysis and material selection, showing that Φeat captures physically-grounded structure beyond semantic grouping. These findings highlight the promise of unsupervised physical feature learning as a foundation for physics-aware perception in vision and graphics. These findings highlight the promise of unsupervised physical feature learning as a foundation for physics-aware perception in vision and graphics.

adobe Adobe
·
Nov 14, 2025 2