Daily Papers

While text-to-3D generation has advanced rapidly, achieving high geometric fidelity at low inference cost remains challenging. Existing text-to-3D methods either decode discrete shape tokens autoregressively or iteratively refine global 3D representations with diffusion or flow models. However, autoregressive decoding is sequential and cannot revise errors, whereas diffusion and flow-matching models repeatedly process the full representation, making high-quality generation increasingly expensive. In this paper, we propose Block3D, a block-wise diffusion framework that partitions the discrete shape-token sequence into contiguous blocks, generates the blocks autoregressively, and jointly denoises all tokens within the current block. To alleviate error accumulation, we introduce confidence-guided intra-block correction, which revises low-confidence tokens before each block is finalized. On a held-out set from TRELLIS-500K, Block3D reduces mean end-to-end generation time from 25.71 seconds to 4.99 seconds, achieving a 5.15times speedup over the fine-tuned autoregressive baseline without sacrificing geometric fidelity.

Clinicians trace cephalometric radiographs following a structured anatomical workflow, yet no prior system encodes this into computation. We present a five-phase anatomy-guided pipeline producing confidence-weighted spatial priors that shape HRNet-W32 training, achieving 1.04 mm mean radial error on 25 landmarks across 1,502 radiographs from 7+ imaging devices. A training x inference prior matrix isolates the mechanism: anatomical priors maintain a 1% validation-to-test gap versus 88% without priors (1.94 mm), despite identical validation convergence. The matrix establishes that all trained models are inference-independent, the expanded architecture alone provides no benefit, random priors yield partial but unstable improvement (1.72 mm), and only image-specific anatomically correct priors produce the 1.04 mm result -- functioning as a training-time regularizer requiring no automated prior generation at deployment. Five-fold cross-validation (p=0.0015), patient-level permutation testing (p<0.0001, n=151), quantified Grad-CAM analysis (88% vs. 74% in-zone activation, p<0.001), and clinical measurement validation (skeletal classification kappa=0.79-0.84, zero Class II<->III reversals, ICC>0.95) provide converging evidence. Cross-domain experiments on echocardiography, cervical spine, and hand radiography support the hypothesis that prior effectiveness scales with the spatial entropy of the landmark distribution.

Delayed outcomes are ubiquitous in online experimentation: treatment can affect whether an outcome occurs, when it occurs, and its realized value. To accommodate staggered entry while remaining robust to environmental nonstationarity and unit-level heterogeneity, we adopt a design-based perspective and target the sample cumulative reward in each arm as a function of calendar time. Our confidence sequences allow practitioners to continuously monitor the counterfactual incremental reward, such as revenue, that would have been realized by calendar time t had all entered units been assigned to treatment rather than control. The main technical challenge is the choice of design-based filtration, complicated by the presence of asynchronous potential outcome times. We show that the IPW treatment-effect estimation error is not a martingale with respect to any filtration, while each arm-specific IPW estimation error is a martingale with respect to a carefully chosen arm-specific event-time filtration. We therefore construct a confidence sequence for the treatment effect by combining two arm-level confidence sequences with a union bound, and further demonstrate that this can outperform the traditional design-based variance upper bound. Finally, we characterize the class of augmentations for which the per-arm AIPW estimation error remains a martingale.

Test-Time Scaling (TTS) methods for enhancing Large Language Model (LLM) reasoning often incur substantial computational costs, primarily due to extensive reliance on external Process Reward Models (PRMs) or sampling methods like Best-of-N (BoN). This paper introduces Guided by Gut (GG), an efficient self-guided TTS framework that achieves PRM-level performance without costly external verifier models. Our method employs a lightweight tree search guided solely by intrinsic LLM signals, token-level confidence and step novelty. One critical innovation is improving the reliability of internal confidence estimates via a targeted reinforcement learning fine-tuning phase. Empirical evaluations on challenging mathematical reasoning benchmarks demonstrate that GG enables smaller models (e.g., 1.5B parameters) to achieve accuracy matching or surpassing significantly larger models (e.g., 32B-70B parameters), while reducing GPU memory usage by up to 10x. Compared to PRM-based methods, GG achieves comparable accuracy with 8x faster inference speeds and 4-5x lower memory usage. Additionally, GG reduces KV cache memory usage by approximately 50% compared to the BoN strategy, facilitating more efficient and practical deployment of TTS techniques.

Accurate and reliable C-arm positioning is essential for fluoroscopy-guided interventions. However, clinical workflows rely on manual alignment that increases radiation exposure and procedural delays. In this work, we present a pipeline that autonomously navigates the C-arm to predefined anatomical landmarks utilizing X-ray images. Given an input X-ray image from an arbitrary starting location on the operating table, the model predicts a 3D displacement vector toward each target landmark along the body. To ensure reliable deployment, we capture both aleatoric and epistemic uncertainties in the model's predictions and further calibrate them using conformal prediction. The derived prediction regions are interpreted as 3D confidence regions around the predicted landmark locations. The training framework combines a probabilistic loss with skeletal pose regularization to encourage anatomically plausible outputs. We validate our approach on a synthetic X-ray dataset generated from DeepDRR. Results show not only strong localization accuracy across multiple architectures but also well-calibrated prediction bounds. These findings highlight the pipeline's potential as a component in safe and reliable autonomous C-arm systems. Code is available at https://github.com/AhmadArrabi/C_arm_guidance_APAH

Large Reasoning Models (LRMs) perform strongly in complex reasoning tasks via Chain-of-Thought (CoT) prompting, but often suffer from verbose outputs caused by redundant content, increasing computational overhead, and degrading user experience. Existing compression methods either operate post-hoc pruning, risking disruption to reasoning coherence, or rely on sampling-based selection, which fails to intervene effectively during generation. In this work, we introduce a confidence-guided perspective to explain the emergence of redundant reflection in LRMs, identifying two key patterns: Confidence Deficit, where the model reconsiders correct steps due to low internal confidence, and Termination Delay, where reasoning continues even after reaching a confident answer. Based on this analysis, we propose ConCISE (Confidence-guided Compression In Step-by-step Efficient Reasoning), a framework that simplifies reasoning chains by reinforcing the model's confidence during inference, thus preventing the generation of redundant reflection steps. It integrates Confidence Injection to stabilize intermediate steps and Early Stopping to terminate reasoning when confidence is sufficient. Extensive experiments demonstrate that fine-tuning LRMs on ConCISE-generated data yields significantly shorter outputs, reducing length by up to approximately 50% under SimPO, while maintaining high task accuracy. ConCISE consistently outperforms existing baselines across multiple reasoning benchmarks.

In the realm of robot-assisted minimally invasive surgery, dynamic scene reconstruction can significantly enhance downstream tasks and improve surgical outcomes. Neural Radiance Fields (NeRF)-based methods have recently risen to prominence for their exceptional ability to reconstruct scenes but are hampered by slow inference speed, prolonged training, and inconsistent depth estimation. Some previous work utilizes ground truth depth for optimization but is hard to acquire in the surgical domain. To overcome these obstacles, we present Endo-4DGS, a real-time endoscopic dynamic reconstruction approach that utilizes 3D Gaussian Splatting (GS) for 3D representation. Specifically, we propose lightweight MLPs to capture temporal dynamics with Gaussian deformation fields. To obtain a satisfactory Gaussian Initialization, we exploit a powerful depth estimation foundation model, Depth-Anything, to generate pseudo-depth maps as a geometry prior. We additionally propose confidence-guided learning to tackle the ill-pose problems in monocular depth estimation and enhance the depth-guided reconstruction with surface normal constraints and depth regularization. Our approach has been validated on two surgical datasets, where it can effectively render in real-time, compute efficiently, and reconstruct with remarkable accuracy.

Semi-supervised learning has become a compelling approach for 3D tooth segmentation from CBCT scans, where labeled data is minimal. However, existing methods still face two persistent challenges: limited corrective supervision in structurally ambiguous or mislabeled regions during supervised training and performance degradation caused by unreliable pseudo-labels on unlabeled data. To address these problems, we propose Region-Aware Instructive Learning (RAIL), a dual-group dual-student, semi-supervised framework. Each group contains two student models guided by a shared teacher network. By alternating training between the two groups, RAIL promotes intergroup knowledge transfer and collaborative region-aware instruction while reducing overfitting to the characteristics of any single model. Specifically, RAIL introduces two instructive mechanisms. Disagreement-Focused Supervision (DFS) Controller improves supervised learning by instructing predictions only within areas where student outputs diverge from both ground truth and the best student, thereby concentrating supervision on structurally ambiguous or mislabeled areas. In the unsupervised phase, Confidence-Aware Learning (CAL) Modulator reinforces agreement in regions with high model certainty while reducing the effect of low-confidence predictions during training. This helps prevent our model from learning unstable patterns and improves the overall reliability of pseudo-labels. Extensive experiments on four CBCT tooth segmentation datasets show that RAIL surpasses state-of-the-art methods under limited annotation. Our code will be available at https://github.com/Tournesol-Saturday/RAIL.

Recent advances in block diffusion language models have demonstrated competitive performance and strong scalability on reasoning tasks. However, existing BDLMs have limited exploration under the test-time scaling setting and face more severe decoding challenges in long Chain-of-Thought reasoning, particularly in balancing the decoding speed and effectiveness. In this work, we propose a unified framework for test-time scaling in BDLMs that introduces adaptivity in both decoding and block-wise generation. At the decoding level, we propose Bounded Adaptive Confidence Decoding (BACD), a difficulty-aware sampling strategy that dynamically adjusts denoising based on model confidence, accelerating inference while controlling error accumulation. Beyond step-wise adaptivity, we introduce Think Coarse, Critic Fine (TCCF), a test-time scaling paradigm that allocates large block sizes to exploratory reasoning and smaller block sizes to refinement, achieving an effective efficiency-effectiveness balance. To enable efficient and effective decoding with a large block size, we adopt Progressive Block Size Extension, which mitigates performance degradation when scaling block sizes. Extensive experiments show that applying BACD and TCCF to TDAR-8B yields significant improvements over strong baselines such as TraDo-8B (2.26x speedup, +11.2 points on AIME24). These results mark an important step toward unlocking the potential of BDLMs for test-time scaling in complex reasoning tasks.

Reliable pelvic bone segmentation (PBS) from CT is essential for robot-assisted pelvic trauma surgery, yet deploying a source-trained model to a new hospital suffers from severe performance degradation due to cross-center domain shifts. While test-time adaptation (TTA) enables online model adaptation without accessing source data, existing methods show limited effectiveness for PBS, facing challenges including boundary degradation, anatomical inconsistency under domain shifts, and voxel-level class imbalance. To address these challenges, we propose a novel closed-loop dynamic Reliability-Guided TTA framework (ReGA) for PBS. Specifically, we introduce a pseudo-label reliability criterion termed Segmentation Inference Consistency Evaluation (SICE), which jointly measures region overlap and boundary deviation via dropout-based ensemble predictions. Based on SICE, a trust-weighted refinement module adaptively updates features to mitigate boundary errors in pseudo-labels. Furthermore, a confidence-weighted region-level contrastive learning strategy is proposed to enforce anatomical consistency. Finally, ReGA follows the teacher-student (TS) scheme to alleviate voxel-level class imbalance. Experiments on three heterogeneous 3D pelvic CT datasets demonstrate that ReGA consistently outperforms state-of-the-art TTA methods, enabling effective adaptation of the source-trained PBS model to unseen clinical domains. The code is available at https://github.com/Ren-ling/ReGA.

The recent success of Large Language Models (LLMs) has catalyzed an increasing interest in their self-correction capabilities. This paper presents a comprehensive investigation into the intrinsic self-correction of LLMs, attempting to address the ongoing debate about its feasibility. Our research has identified an important latent factor - the "confidence" of LLMs - during the self-correction process. Overlooking this factor may cause the models to over-criticize themselves, resulting in unreliable conclusions regarding the efficacy of self-correction. We have experimentally observed that LLMs possess the capability to understand the "confidence" in their own responses. It motivates us to develop an "If-or-Else" (IoE) prompting framework, designed to guide LLMs in assessing their own "confidence", facilitating intrinsic self-corrections. We conduct extensive experiments and demonstrate that our IoE-based Prompt can achieve a consistent improvement regarding the accuracy of self-corrected responses over the initial answers. Our study not only sheds light on the underlying factors affecting self-correction in LLMs, but also introduces a practical framework that utilizes the IoE prompting principle to efficiently improve self-correction capabilities with "confidence". The code is available at https://github.com/MBZUAI-CLeaR/IoE-Prompting.git.

Diffusion language models are structurally well-suited for iterative error correction, as their non-causal denoising dynamics allow arbitrary positions in a sequence to be revised. However, standard masked diffusion language model (MDLM) training fails to reliably induce this behavior, as models often cannot identify unreliable tokens in a complete input, rendering confidence-guided refinement ineffective. We study corrective behavior in diffusion language models, defined as the ability to assign lower confidence to incorrect tokens and iteratively refine them while preserving correct content. We show that this capability is not induced by conventional masked diffusion objectives and propose a correction-oriented post-training principle that explicitly supervises visible incorrect tokens, enabling error-aware confidence and targeted refinement. To evaluate corrective behavior, we introduce the Code Revision Benchmark (CRB), a controllable and executable benchmark for assessing error localization and in-place correction. Experiments on code revision tasks and controlled settings demonstrate that models trained with our approach substantially outperform standard MDLMs in correction scenarios, while also improving pure completion performance. Our code is publicly available at https://github.com/zhangshuibai/CDLM.

Diffusion-based large language models (dLLMs) are gaining attention for their inherent capacity for parallel decoding, offering a compelling alternative to autoregressive LLMs. Among various decoding strategies, blockwise semi-autoregressive (semi-AR) approaches are widely adopted due to their natural support for KV caching and their favorable accuracy-speed trade-off. However, this paper identifies two fundamental limitations in the conventional semi-AR decoding approach that applies a fixed block size: i) late decoding overhead, where the unmasking of high-confidence tokens outside the current block is unnecessarily delayed, and ii) premature decoding error, where low-confidence tokens inside the current block are committed too early, leading to incorrect tokens. This paper presents the first systematic investigation challenging the fixed block size assumption in semi-AR decoding. Through a statistical analysis of confidence dynamics during the denoising process, we identify a volatility band (VB) region during dLLM decoding, which encodes local semantic structure and can be used to guide adaptive block sizing. Leveraging these insights, we introduce AdaBlock-dLLM, a training-free, plug-and-play scheduler that adaptively aligns block boundaries with semantic steps by adjusting block size during runtime. Extensive experiments across diverse benchmarks show that AdaBlock-dLLM achieves up to 5.3% accuracy improvement under the same throughput budget. Beyond inference-time optimization, we hope our semantics-aware adaptive scheduling approach and confidence-based analysis will inspire future training strategies for dLLMs.

Diffusion language models decode text by iteratively denoising masked token sequences, making the choice of which positions to decode a central inference-time decision. Most training-free decoding strategies use model confidence for position selection, assuming that high-confidence positions are ready to be decoded. In this work, we revisit this assumption by studying when confidence misleads fully non-autoregressive (fully non-AR) decoding. EOT tokens can receive high confidence and cause incomplete generation; inserting a suffix anchor can mitigate this issue but introduces local overconfidence near the anchor, causing anchor-adjacent tokens to be decoded too early. To address these issues, we propose Suffix-Anchored Confidence Modulation, a simple training-free method that inserts a short suffix anchor to encourage response completion and modulates confidence near the anchor according to decoding progress. This preserves the response-completion benefit of suffix anchoring while reducing premature decoding of anchor-adjacent tokens. Across text-only reasoning, vision-language reasoning, and code-generation benchmarks, our method consistently improves confidence-based fully non-AR decoding, outperforms explicit EOT suppression, and preserves the parallel decoding advantage of fully non-AR generation.

Despite their vast capabilities, Large Language Models (LLMs) often struggle with generating reliable outputs, frequently producing high-confidence inaccuracies known as hallucinations. Addressing this challenge, our research introduces InternalInspector, a novel framework designed to enhance confidence estimation in LLMs by leveraging contrastive learning on internal states including attention states, feed-forward states, and activation states of all layers. Unlike existing methods that primarily focus on the final activation state, InternalInspector conducts a comprehensive analysis across all internal states of every layer to accurately identify both correct and incorrect prediction processes. By benchmarking InternalInspector against existing confidence estimation methods across various natural language understanding and generation tasks, including factual question answering, commonsense reasoning, and reading comprehension, InternalInspector achieves significantly higher accuracy in aligning the estimated confidence scores with the correctness of the LLM's predictions and lower calibration error. Furthermore, InternalInspector excels at HaluEval, a hallucination detection benchmark, outperforming other internal-based confidence estimation methods in this task.

Visual Prompt Tuning (VPT) is an effective tuning method for adapting pretrained Vision Transformers (ViTs) to downstream tasks. It leverages extra learnable tokens, known as prompts, which steer the frozen pretrained ViTs. Although VPT has demonstrated its applicability with supervised vision transformers, it often underperforms with self-supervised ones. Through empirical observations, we deduce that the effectiveness of VPT hinges largely on the ViT blocks with which the prompt tokens interact. Specifically, VPT shows improved performance on image classification tasks for MAE and MoCo v3 when the prompt tokens are inserted into later blocks rather than the first block. These observations suggest that there exists an optimal location of blocks for the insertion of prompt tokens. Unfortunately, identifying the optimal blocks for prompts within each self-supervised ViT for diverse future scenarios is a costly process. To mitigate this problem, we propose a simple yet effective method that learns a gate for each ViT block to adjust its intervention into the prompt tokens. With our method, prompt tokens are selectively influenced by blocks that require steering for task adaptation. Our method outperforms VPT variants in FGVC and VTAB image classification and ADE20K semantic segmentation. The code is available at https://github.com/ryongithub/GatedPromptTuning.

Diffusion models have opened the path to a wide range of text-based image editing frameworks. However, these typically build on the multi-step nature of the diffusion backwards process, and adapting them to distilled, fast-sampling methods has proven surprisingly challenging. Here, we focus on a popular line of text-based editing frameworks - the ``edit-friendly'' DDPM-noise inversion approach. We analyze its application to fast sampling methods and categorize its failures into two classes: the appearance of visual artifacts, and insufficient editing strength. We trace the artifacts to mismatched noise statistics between inverted noises and the expected noise schedule, and suggest a shifted noise schedule which corrects for this offset. To increase editing strength, we propose a pseudo-guidance approach that efficiently increases the magnitude of edits without introducing new artifacts. All in all, our method enables text-based image editing with as few as three diffusion steps, while providing novel insights into the mechanisms behind popular text-based editing approaches.

Converting free-text cardiac magnetic resonance (CMR) reports into auditable structured data remains a bottleneck for cohort assembly, longitudinal curation, and clinical decision support. We present CMR-EXTR, a lightweight framework that converts free-text CMR reports into structured data and assigns per-field confidence for quality control. A teacher-student distillation pipeline enables fully offline inference while limiting manual annotation. Uncertainty integrates three complementary principles -- distribution plausibility, sampling stability, and cross-field consistency -- to triage human review. Experiments show that CMR-EXTR achieves 99.65% variable-level accuracy, demonstrating both reliable extraction and informative confidence scores. To our knowledge, this is the first CMR-specific extraction system with integrated confidence estimation. The code is available at https://github.com/yuyi1005/CMR-EXTR.

Despite the significant progress in diffusion prior-based image restoration, most existing methods apply uniform processing to the entire image, lacking the capability to perform region-customized image restoration according to user instructions. In this work, we propose a new framework, namely InstructRestore, to perform region-adjustable image restoration following human instructions. To achieve this, we first develop a data generation engine to produce training triplets, each consisting of a high-quality image, the target region description, and the corresponding region mask. With this engine and careful data screening, we construct a comprehensive dataset comprising 536,945 triplets to support the training and evaluation of this task. We then examine how to integrate the low-quality image features under the ControlNet architecture to adjust the degree of image details enhancement. Consequently, we develop a ControlNet-like model to identify the target region and allocate different integration scales to the target and surrounding regions, enabling region-customized image restoration that aligns with user instructions. Experimental results demonstrate that our proposed InstructRestore approach enables effective human-instructed image restoration, such as images with bokeh effects and user-instructed local enhancement. Our work advances the investigation of interactive image restoration and enhancement techniques. Data, code, and models will be found at https://github.com/shuaizhengliu/InstructRestore.git.

Large language models can detect their own errors and sometimes correct them without external feedback, but the underlying mechanisms remain unknown. We investigate this through the lens of second-order models of confidence from decision neuroscience. In a first-order system, confidence derives from the generation signal itself and is therefore maximal for the chosen response, precluding error detection. Second-order models posit a partially independent evaluative signal that can disagree with the committed response, providing the basis for error detection. Kumaran et al. (2026) showed that LLMs cache a confidence representation at a token immediately following the answer (i.e. post-answer newline: PANL) -- that causally drives verbal confidence and dissociates from log-probabilities. Here we test whether this PANL signal extends beyond confidence to support error detection and self-correction. Here we test whether this signal supports error detection and self-correction, deriving predictions from the second-order framework. Using a verify-then-correct paradigm, we show that: (i) verbal confidence predicts error detection far beyond token log-probabilities, ruling out a first-order account; (ii) PANL activations predict error detection beyond verbal confidence itself; and (iii) PANL predicts which errors the model can correct -- where all behavioural signals fail. Causal interventions confirm that PANL signals rescue error detection behavior when answer information is corrupted. All findings replicate across models (Gemma 3 27B and Qwen 2.5 7B) and tasks (TriviaQA and MNLI). These results reveal that LLMs naturally implement a second-order confidence architecture whose internal evaluative signal encodes not only whether an answer is likely wrong but whether the model has the knowledge to fix it.

In this paper, we present PRISM, a Promptable and Robust Interactive Segmentation Model, aiming for precise segmentation of 3D medical images. PRISM accepts various visual inputs, including points, boxes, and scribbles as sparse prompts, as well as masks as dense prompts. Specifically, PRISM is designed with four principles to achieve robustness: (1) Iterative learning. The model produces segmentations by using visual prompts from previous iterations to achieve progressive improvement. (2) Confidence learning. PRISM employs multiple segmentation heads per input image, each generating a continuous map and a confidence score to optimize predictions. (3) Corrective learning. Following each segmentation iteration, PRISM employs a shallow corrective refinement network to reassign mislabeled voxels. (4) Hybrid design. PRISM integrates hybrid encoders to better capture both the local and global information. Comprehensive validation of PRISM is conducted using four public datasets for tumor segmentation in the colon, pancreas, liver, and kidney, highlighting challenges caused by anatomical variations and ambiguous boundaries in accurate tumor identification. Compared to state-of-the-art methods, both with and without prompt engineering, PRISM significantly improves performance, achieving results that are close to human levels. The code is publicly available at https://github.com/MedICL-VU/PRISM.

High-resolution image editing is increasingly demanded in professional workflows, yet existing diffusion-based models remain constrained to resolutions below 1K due to quadratic attention complexity and prohibitive memory requirements. A prevalent workaround employs a two-stage pipeline: editing at low resolution followed by independent super-resolution. However, this approach suffers from two critical issues: information divergence, where hallucinated details contradict the original high-resolution (HR) source, and texture degradation, manifesting as over-smoothed or over-sharpened artifacts. We propose EditBridge, a diffusion bridge framework for efficient ultra high-resolution editing. Unlike conventional diffusion that regenerates from noise, we formulate refinement as structured data-to-data translation from the low-resolution (LR) edited result to its HR counterpart, explicitly conditioned on the original HR source to preserve authentic details. To efficiently incorporate HR source guidance, we introduce a prior-guided block-wise sparse attention mechanism that exploits semantic correspondence from first-stage editing to constrain cross-image interactions to spatially aligned regions, significantly reducing computational overhead. Extensive experiments demonstrate that EditBridge achieves high-fidelity editing with superior perceptual quality at resolutions up to 4K, delivering 3.6--8.4times speedup at 2K and enabling practical 4K editing in 61 seconds.

Multimodal large language models (MLLMs) hold considerable promise for applications in healthcare. However, their deployment in safety-critical settings is hindered by two key limitations: (i) sensitivity to prompt design, and (ii) a tendency to generate incorrect responses with high confidence. As clinicians may rely on a model's stated confidence to gauge the reliability of its predictions, it is especially important that when a model expresses high confidence, it is also highly accurate. We introduce Prompt4Trust, the first reinforcement learning (RL) framework for prompt augmentation targeting confidence calibration in MLLMs. A lightweight LLM is trained to produce context-aware auxiliary prompts that guide a downstream task MLLM to generate responses in which the expressed confidence more accurately reflects predictive accuracy. Unlike conventional calibration techniques, Prompt4Trust specifically prioritizes aspects of calibration most critical for safe and trustworthy clinical decision-making. Beyond improvements driven by this clinically motivated calibration objective, our proposed method also improves task accuracy, achieving state-of-the-art medical visual question answering (VQA) performance on the PMC-VQA benchmark, which is composed of multiple-choice questions spanning diverse medical imaging modalities. Moreover, our framework trained with a small downstream task MLLM showed promising zero-shot generalization to larger MLLMs in our experiments, suggesting the potential for scalable calibration without the associated computational costs. This work demonstrates the potential of automated yet human-aligned prompt engineering for improving the the trustworthiness of MLLMs in safety critical settings. Our codebase can be found at https://github.com/xingbpshen/prompt4trust.

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on internal knowledge during reasoning, leading to hallucinated reasoning and factual inaccuracies when encountering cases beyond their training scope. Although recent Agentic Retrieval-Augmented Generation (RAG) methods elicit the medical model's proactive retrieval ability during reasoning, they are confined to unimodal LLMs, neglecting the crucial visual information during reasoning and retrieval. Consequently, we propose the first Multimodal Medical Reasoning-with-Retrieval framework, Med-RwR, which actively retrieves external knowledge by querying observed symptoms or domain-specific medical concepts during reasoning. Specifically, we design a two-stage reinforcement learning strategy with tailored rewards that stimulate the model to leverage both visual diagnostic findings and textual clinical information for effective retrieval. Building on this foundation, we further propose a Confidence-Driven Image Re-retrieval (CDIR) method for test-time scaling when low prediction confidence is detected. Evaluation on various public medical benchmarks demonstrates Med-RwR's significant improvements over baseline models, proving the effectiveness of enhancing reasoning capabilities with external knowledge integration. Furthermore, Med-RwR demonstrates remarkable generalizability to unfamiliar domains, evidenced by 8.8% performance gain on our proposed EchoCardiography Benchmark (ECBench), despite the scarcity of echocardiography data in the training corpus. Our data, model, and codes will be made publicly available at https://github.com/xmed-lab/Med-RwR.

Gastrointestinal malignancies constitute a leading cause of cancer-related mortality worldwide, with advanced-stage prognosis remaining particularly dismal. Originating as a groundbreaking technique for early gastric cancer treatment, Endoscopic Submucosal Dissection has evolved into a versatile intervention for diverse gastrointestinal lesions. While computer-assisted systems significantly enhance procedural precision and safety in ESD, their clinical adoption faces a critical bottleneck: reliable surgical phase recognition within complex endoscopic workflows. Current state-of-the-art approaches predominantly rely on multi-stage refinement architectures that iteratively optimize temporal predictions. In this paper, we present Clinical Prior Knowledge-Constrained Diffusion (CPKD), a novel generative framework that reimagines phase recognition through denoising diffusion principles while preserving the core iterative refinement philosophy. This architecture progressively reconstructs phase sequences starting from random noise and conditioned on visual-temporal features. To better capture three domain-specific characteristics, including positional priors, boundary ambiguity, and relation dependency, we design a conditional masking strategy. Furthermore, we incorporate clinical prior knowledge into the model training to improve its ability to correct phase logical errors. Comprehensive evaluations on ESD820, Cholec80, and external multi-center demonstrate that our proposed CPKD achieves superior or comparable performance to state-of-the-art approaches, validating the effectiveness of diffusion-based generative paradigms for surgical phase recognition.

Rib fractures are common and time-consuming to localize on computed tomography (CT). We ask whether fractures detected independently in two orthogonal CT-derived projections (anteroposterior and lateral) can be paired across views and triangulated into reliable 3D points at a controlled rate of false outputs, and we answer it with a staged diagnostic study. The projection geometry is exact, and given correct correspondence, localization is accurate (median 4.0 mm, 88% within 10 mm, 93.6% rib-exact). On a sealed 55-case cohort, a large share of fractures is in principle recoverable (61.1% dual-view availability, and a correct pair present in the candidate graph for 58.4% of fractures), yet the binding limitation is neither geometry nor localization but confidence-limited cross-view correspondence. A controlled detector-by-correspondence factorial attributes the operational gain to lateral-detector quality rather than the tested matching methods; retraining the lateral detector produces the first nonzero controlled-budget reconstructions. Under a deliberately conservative commitment policy, a pre-specified sealed pass promotes 15 of 601 fractures to correct 3D localizations at 0.436 false points per case (2.50% end-to-end commitment yield), and committed points are accurate (median 1.49 mm, 93% rib-exact). The low yield is a consequence of confidence-gated abstention, not of geometry or detection: the study establishes a reproducible framework for selective 3D localization and identifies cross-view correspondence as the dominant operational bottleneck.

Recently, diffusion-based methods, like InstructPix2Pix (IP2P), have achieved effective instruction-based image editing, requiring only natural language instructions from the user. However, these methods often inadvertently alter unintended areas and struggle with multi-instruction editing, resulting in compromised outcomes. To address these issues, we introduce the Focus on Your Instruction (FoI), a method designed to ensure precise and harmonious editing across multiple instructions without extra training or test-time optimization. In the FoI, we primarily emphasize two aspects: (1) precisely extracting regions of interest for each instruction and (2) guiding the denoising process to concentrate within these regions of interest. For the first objective, we identify the implicit grounding capability of IP2P from the cross-attention between instruction and image, then develop an effective mask extraction method. For the second objective, we introduce a cross attention modulation module for rough isolation of target editing regions and unrelated regions. Additionally, we introduce a mask-guided disentangle sampling strategy to further ensure clear region isolation. Experimental results demonstrate that FoI surpasses existing methods in both quantitative and qualitative evaluations, especially excelling in multi-instruction editing task.

Diffusion-based editing has rapidly evolved from curated inpainting tools into general-purpose editors spanning text-guided instruction following, mask-localized edits, drag-based geometric manipulation, exemplar transfer, and training-free composition systems. Despite strong empirical progress, the field lacks a unified treatment of core desiderata that govern practical usability: controllability (how precisely and continuously the user can specify an edit), faithfulness to user intent (semantic alignment to instructions), semantic consistency (preservation of identity and non-target content), locality (containment of changes), and perceptual quality (artifact suppression and detail retention). This paper provides a theoretical and empirical analysis of general diffusion-based image editing, connecting diverse paradigms through a common view of editing as guided transport on a learned image manifold. We first formalize editing as an operator induced by a conditional reverse-time generative process and define task-agnostic metrics capturing instruction adherence, region preservation, semantic consistency, and stability under repeated edits. We then develop theory describing edit dynamics under (i) noise-injection and denoising transport, (ii) inversion-and-edit pipelines and the propagation of inversion errors, and (iii) locality constraints implemented via masked guidance or hard constraints. Under mild Lipschitz assumptions on the learned score or flow field, we derive bounds connecting guidance strength and inversion error to measurable deviations in non-target regions, and we characterize accumulation effects under iterative multi-turn editing. Empirically, we benchmark representative paradigms.

Safety-aligned language models systematically refuse harmful requests. While activation steering can modulate refusal, ablating the raw "refusal vector" calculated from contrastive harmful and harmless prompts often causes collateral damage and distribution drift. We argue this degradation occurs because the raw vector is polysemantic, entangling the refusal signal with core capability circuits and linguistic style. We introduce Surgical Refusal Ablation (SRA) to distill these steering directions. SRA constructs a registry of independent Concept Atoms representing protected capabilities and stylistic confounds, then uses ridge-regularized spectral residualization to orthogonalize the refusal vector against these directions. This yields a clean refusal direction that targets refusal-relevant structure while minimizing disruption to the model's semantic geometry. Across five models (Qwen3-VL and Ministral series), SRA achieves deep refusal reduction (0-2%) with negligible perplexity impact on Wikitext-2 (mean delta PPL approx. 0.02) and minimal distribution drift. Notably, standard ablation on Qwen3-VL-4B induces severe drift (first-token KL = 2.088), whereas SRA maintains the original distribution (KL = 0.044) while achieving the same 0% refusal rate. Using teacher-forced perplexity on GSM8K and MBPP as a high-resolution capability proxy, we show SRA preserves math and code distributions. These results suggest that common "model damage" is often "Ghost Noise," defined as the spectral bleeding of the dirty refusal direction into capability subspaces.

Despite recent advances in inversion-based editing, text-guided image manipulation remains challenging for diffusion models. The primary bottlenecks include 1) the time-consuming nature of the inversion process; 2) the struggle to balance consistency with accuracy; 3) the lack of compatibility with efficient consistency sampling methods used in consistency models. To address the above issues, we start by asking ourselves if the inversion process can be eliminated for editing. We show that when the initial sample is known, a special variance schedule reduces the denoising step to the same form as the multi-step consistency sampling. We name this Denoising Diffusion Consistent Model (DDCM), and note that it implies a virtual inversion strategy without explicit inversion in sampling. We further unify the attention control mechanisms in a tuning-free framework for text-guided editing. Combining them, we present inversion-free editing (InfEdit), which allows for consistent and faithful editing for both rigid and non-rigid semantic changes, catering to intricate modifications without compromising on the image's integrity and explicit inversion. Through extensive experiments, InfEdit shows strong performance in various editing tasks and also maintains a seamless workflow (less than 3 seconds on one single A40), demonstrating the potential for real-time applications. Project Page: https://sled-group.github.io/InfEdit/

Conditioning image generation facilitates seamless editing and the creation of photorealistic images. However, conditioning on noisy or Out-of-Distribution (OoD) images poses significant challenges, particularly in balancing fidelity to the input and realism of the output. We introduce Confident Ordinary Differential Editing (CODE), a novel approach for image synthesis that effectively handles OoD guidance images. Utilizing a diffusion model as a generative prior, CODE enhances images through score-based updates along the probability-flow Ordinary Differential Equation (ODE) trajectory. This method requires no task-specific training, no handcrafted modules, and no assumptions regarding the corruptions affecting the conditioning image. Our method is compatible with any diffusion model. Positioned at the intersection of conditional image generation and blind image restoration, CODE operates in a fully blind manner, relying solely on a pre-trained generative model. Our method introduces an alternative approach to blind restoration: instead of targeting a specific ground truth image based on assumptions about the underlying corruption, CODE aims to increase the likelihood of the input image while maintaining fidelity. This results in the most probable in-distribution image around the input. Our contributions are twofold. First, CODE introduces a novel editing method based on ODE, providing enhanced control, realism, and fidelity compared to its SDE-based counterpart. Second, we introduce a confidence interval-based clipping method, which improves CODE's effectiveness by allowing it to disregard certain pixels or information, thus enhancing the restoration process in a blind manner. Experimental results demonstrate CODE's effectiveness over existing methods, particularly in scenarios involving severe degradation or OoD inputs.

We present CadLLM, a training-free method to accelerate the inference throughput of diffusion-based LLMs (dLLMs). We first investigate the dynamic nature of token unmasking confidence across blocks and steps. Based on this observation, we present a lightweight adaptive approach that controls the generation block size, step size, and threshold based on the average confidence of unmasked tokens. We further reduce softmax overhead by dynamically leveraging a subset of the vocabulary to regulate sampling breadth. CadLLM is a plug-and-play, model-agnostic method compatible with KV-cache-based dLLMs. Extensive experiments on four popular tasks demonstrate that CadLLM yields up to 2.28x throughput improvement over the state-of-the-art baseline with competitive accuracy.

Small instruct-tuned LLMs produce degenerate verbal confidence under minimal elicitation: ceiling rates above 95%, near-chance Type-2 AUROC, and Invalid validity profiles. We test whether confidence-conditioned supervised fine-tuning (CSFT) with self-consistency-derived targets can close the gap between internal information and verbal readout. A pre-registered Phase 0 protocol on Gemma 3 4B-it with a modal filter restricting training to items with correct modal answers produced a negative result: AUROC2 dropped from 0.554 to 0.509 due to label-entropy collapse in the training targets. An exploratory rescue removed the filter, training on all 2,000 calibration items. This produced a binary verbal correctness discriminator with AUROC2 = 0.774 on held-out TriviaQA, compressing a 10-sample self-consistency signal (AUROC2 = 0.999) into a single-pass readout exceeding logit entropy (0.701). The shuffled-target control showed no improvement (0.501). On MMLU, accuracy improved from 54.2% to 77.4% with the shuffled model at baseline (56.1%), supporting a target-dependent interpretation. The result is exploratory, binary rather than continuously calibrated, and observed at a single scale. It identifies two design lessons: confidence training requires label entropy, and correct targets regularise output format.

This is the technique report for the winning solution of the CVPR2024 GenAI Media Generation Challenge Workshop's Instruction-guided Image Editing track. Instruction-guided image editing has been largely studied in recent years. The most advanced methods, such as SmartEdit and MGIE, usually combine large language models with diffusion models through joint training, where the former provides text understanding ability, and the latter provides image generation ability. However, in our experiments, we find that simply connecting large language models and image generation models through intermediary guidance such as masks instead of joint fine-tuning leads to a better editing performance and success rate. We use a 4-step process IIIE (Inpainting-based Instruction-guided Image Editing): editing category classification, main editing object identification, editing mask acquisition, and image inpainting. Results show that through proper combinations of language models and image inpainting models, our pipeline can reach a high success rate with satisfying visual quality.

Reliable procedural monitoring in video requires exposure to naturally occurring human errors and the recoveries that follow. In egocentric recordings, mistakes are often partially occluded by hands and revealed through subtle object state changes, while existing procedural datasets provide limited and inconsistent mistake and correction traces. We present PIE-V (Psychologically Inspired Error injection for Videos), a framework for constructing and benchmarking mistake-aware egocentric procedural videos by augmenting clean keystep procedures with controlled, human-plausible deviations. PIE-V combines a psychology-informed error planner conditioned on procedure phase and semantic step load, a correction planner that models recovery behavior, an LLM writer that performs cascade-consistent rewrites, and an LLM judge that validates procedural coherence and repairs failures. For video segment edits, PIE-V synthesizes replacement clips with text-guided video generation and stitches them into the episode to preserve visual plausibility. Applied to 17 tasks and 50 Ego-Exo4D scenarios, PIE-V injects 102 mistakes and generates 27 recovery corrections. For benchmarking, we introduce a unified taxonomy and a human rubric with nine metrics that cover step-level and procedure-level quality, including plausibility, procedure logic with annotator confidence, state change coherence, and grounding between text and video. Using this protocol, we audit several existing resources and compare PIE-V against a freeform LLM generation baseline under the same criteria. Together, the framework and rubric support post-completion verification for egocentric procedural mistake detection and correction.

Deep models for retinal optical coherence tomography (OCT) classification report high accuracy but rarely report whether their confidence can be trusted -- a gap that matters when a wrong-but-confident reading delays sight-saving treatment. We pair a hybrid convolutional-Transformer encoder with a gradient-boosting (XGBoost) classification head and a three-part clinical safety layer: confidence calibration, out-of-distribution (OOD) rejection, and per-prediction uncertainty flagging. On four-class OCT (84,495 scans) the model reaches 95.4% accuracy while cutting calibration error twelve-fold (expected calibration error, ECE = 0.0024), so the confidence it reports tracks its true accuracy. To our knowledge this is the first OCT classifier to validate all three safety mechanisms jointly, with public weights and reproducible multi-seed evaluation.

Segmentation of the main coronary artery from X-ray coronary angiography (XCA) sequences is crucial for the diagnosis of coronary artery diseases. However, this task is challenging due to issues such as blurred boundaries, inconsistent radiation contrast, complex motion patterns, and a lack of annotated images for training. Although Semi-Supervised Learning (SSL) can alleviate the annotation burden, conventional methods struggle with complicated temporal dynamics and unreliable uncertainty quantification. To address these challenges, we propose SAM3-based Teacher-student framework with Motion-Aware consistency and Progressive Confidence Regularization (SMART), a semi-supervised vessel segmentation approach for X-ray angiography videos. First, our method utilizes SAM3's unique promptable concept segmentation design and innovates a SAM3-based teacher-student framework to maximize the performance potential of both the teacher and the student. Second, we enhance segmentation by integrating the vessel mask warping technique and motion consistency loss to model complex vessel dynamics. To address the issue of unreliable teacher predictions caused by blurred boundaries and minimal contrast, we further propose a progressive confidence-aware consistency regularization to mitigate the risk of unreliable outputs. Extensive experiments on three datasets of XCA sequences from different institutions demonstrate that SMART achieves state-of-the-art performance while requiring significantly fewer annotations, making it particularly valuable for real-world clinical applications where labeled data is scarce. Our code is available at: https://github.com/qimingfan10/SMART.

We report that model quantisation restructures domain-level metacognitive efficiency in LLMs rather than degrading it uniformly. Evaluating Llama-3-8B-Instruct on the same 3,000 questions at Q5_K_M and f16 precision, we find that M-ratio profiles across four knowledge domains are uncorrelated between formats (Spearman rho = 0.00). Arts & Literature moves from worst-monitored (M-ratio = 0.606 at Q5_K_M) to best-monitored (1.542 at f16). Geography moves from well-monitored (1.210) to under-monitored (0.798). However, Type-2 AUROC profiles are perfectly stable across formats (rho = 1.00), localising the restructuring to the M-ratio normalisation rather than the underlying discrimination signal. This finding emerged from a pre-registered attempt to improve metacognition through domain-conditional training. We prescribed confidence-amplification SFT for the diagnosed weak domain, with matched-budget agnostic and wrong-prescription controls. All four confirmatory hypotheses were null (10,000 bootstrap resamples, seed = 42). The training successfully reshaped confidence distributions, doubling the NLP gap in Science from 0.076 to 0.152, but did not improve meta-d' because the diagnostic profile did not transfer across formats. Any system relying on domain-level M-ratio profiles has an unexamined dependency on inference format. Systems using AUROC_2 are safer. We release all code, pre-registrations, and trial-level data.

Existing image inpainting methods often produce artifacts when dealing with large holes in real applications. To address this challenge, we propose an iterative inpainting method with a feedback mechanism. Specifically, we introduce a deep generative model which not only outputs an inpainting result but also a corresponding confidence map. Using this map as feedback, it progressively fills the hole by trusting only high-confidence pixels inside the hole at each iteration and focuses on the remaining pixels in the next iteration. As it reuses partial predictions from the previous iterations as known pixels, this process gradually improves the result. In addition, we propose a guided upsampling network to enable generation of high-resolution inpainting results. We achieve this by extending the Contextual Attention module to borrow high-resolution feature patches in the input image. Furthermore, to mimic real object removal scenarios, we collect a large object mask dataset and synthesize more realistic training data that better simulates user inputs. Experiments show that our method significantly outperforms existing methods in both quantitative and qualitative evaluations. More results and Web APP are available at https://zengxianyu.github.io/iic.

As LLMs generate increasingly long outputs, effective uncertainty estimation must identify errors at fine-grained levels rather than discard entire responses. While such methods exist, evaluating uncertainty at any resolution (token to an entire generation) is challenging and highly sensitive to label imperfections, making zero-noise benchmarks essential; yet, long-form generation benchmarks tend to rely on fallible labels rather than deterministic ground truth. We introduce Single-answer Atomic Long-form Target (SALT), a benchmark of six procedurally generated tasks with single deterministic long textual ground truths, enabling unit-level evaluation of correctness, calibration, and ranking without external judges. Equipped with SALT, our analysis of 50+ LLMs reveals key insights: We identify which confidence functions dominate each uncertainty aspect and show that confidence ranking largely breaks at atomic resolution, even when clearer separability emerges at coarser line-level units. SALT further enables controlled atom-level interventions throughout generation, revealing two separable drivers of future errors: propagation from corrupted prefixes, dominated by global context correctness, and bounded degradation from increasing answer-context length. Finally, we demonstrate that reasoning, via Chain-of-Thought prompting or internalized through training, introduces a trade-off, improving accuracy while degrading confidence ranking. These findings directly impact risk-critical applications requiring reliable error identification and mitigation.

Online surgical phase recognition (SPR) underpins context-aware operating-room systems and requires committing to a prediction at every frame from past context alone. Surgical video poses three demands that natural-video recognizers do not jointly address: procedures span tens of thousands of frames, time flows non-uniformly as long routine stretches are punctuated by brief phase-defining transitions, and the visual domain is narrow so backbone features are strongly correlated across channels. Existing recognizers either let per-frame cost grow with elapsed length, or hold cost bounded but advance state at a uniform rate with channel-independent dynamics, leaving the latter two demands unaddressed. We present SurgicalMamba, a causal SPR model built on Mamba2's structured state-space duality (SSD) that holds per-frame cost at O(d). It introduces three SSD-compatible components, each targeting one demand: a dual-path SSD block that separates long- and short-term regimes at the level of recurrent state; intensity-modulated stepping, a continuous-time time-warp that adapts the slow path's effective rate to phase-relevant information; and state regramming, a per-chunk Cayley rotation that opens cross-channel mixing in the otherwise axis-aligned SSM recurrence. The learned rotation planes inherit a phase-aligned structure without any direct supervision, offering an interpretable internal signature of surgical workflow. Across seven public SPR benchmarks, SurgicalMamba reaches state-of-the-art accuracy and phase-level Jaccard under strict online evaluation: 94.6%/82.7% on Cholec80 (+0.7 pp/+2.2 pp over the strongest prior) and 89.5%/68.9% on AutoLaparo (+1.7 pp/+2.0 pp), at 119 fps on a single GPU. Ablations isolate the contribution of each component. The code is publicly available at https://github.com/sukjuoh/Surgical-Mamba.

We present Interactive Neural Video Editing (INVE), a real-time video editing solution, which can assist the video editing process by consistently propagating sparse frame edits to the entire video clip. Our method is inspired by the recent work on Layered Neural Atlas (LNA). LNA, however, suffers from two major drawbacks: (1) the method is too slow for interactive editing, and (2) it offers insufficient support for some editing use cases, including direct frame editing and rigid texture tracking. To address these challenges we leverage and adopt highly efficient network architectures, powered by hash-grids encoding, to substantially improve processing speed. In addition, we learn bi-directional functions between image-atlas and introduce vectorized editing, which collectively enables a much greater variety of edits in both the atlas and the frames directly. Compared to LNA, our INVE reduces the learning and inference time by a factor of 5, and supports various video editing operations that LNA cannot. We showcase the superiority of INVE over LNA in interactive video editing through a comprehensive quantitative and qualitative analysis, highlighting its numerous advantages and improved performance. For video results, please see https://gabriel-huang.github.io/inve/

Large language models (LLMs) are increasingly applied to structured clinical data, yet whether they can recognize the limits of their own knowledge on such tasks remains unexplored. We study this question through the lens of cross-model attribution divergence with the goal of reducing epistemic uncertainty for structured tasks, comparing Qwen 2.5 7B and XGBoost on a prediction task via attribution divergence analysis. We report four findings. First, LLM verbalized confidence is epistemically vacuous, it outputs a near-constant (0.856-0.937) regardless of whether accuracy is 49% or 75.3%, tracking prompt format rather than prediction quality. Second, the LLM exhibits an inverse difficulty effect: accuracy drops to 64.8% when XGBoost is 99% correct, but matches XGBoost (73.8% vs. 73.1%) when it is moderately uncertain. Third, few-shot examples and SHAP-derived feature evidence are orthogonal, super-additive interventions: they reduce the Attribution Disagreement Score (ADS) from 1.54 to 0.38 and improve accuracy from 49% to 75.3% without training. Fourth, a cross-model calibrator that determined LLM reliability using attribution divergence signals reduces expected calibration error from 0.254 to 0.080, replacing uninformative verbalized confidence with patient-specific reliability estimates, without accessing model internals or requiring repeated inference. We frame these findings as a cold start problem for LLMs on structured data and outline a path toward genuine epistemic self-awareness.

Yes. Can it cure doom loops? Probably not. The Gemma 4 instruction-tuned models share a reproducible failure: on long factual enumeration prompts, such as listing every episode of a TV series, the 88 IAU constellations, or the 151 original Pokemon, they collapse into repetition, either a tight verbatim loop or a list whose entries decay onto a single answer. These loops occur at rates as high as 95% and survive prompt rewording, inference-engine changes, and most sampling adjustments. In this paper we explore whether this behavior is localized enough to remove by weight edits. To localize the cause, we use per-layer ablation and per-neuron attribution, then confirm the strongest candidates with full-generation sweeps. The loops trace to a small set of MLP neurons (or, in the 26B-A4B Mixture-of-Experts model, a few routed experts) which we suppress with static weight edits. These "surgeries" can be as small as a single sign-inverted neuron (in the E2B model). The size of the effective edits grows with model scale, but in all cases, the loop patterns can be addressed at normal generation budgets while preserving general-purpose benchmark scores. However, the edits do not solve everything: we also study longer thinking budgets, where the two larger models most visibly enter doom looping, i.e. a non-convergent regime in which the model self-corrects in circles over a fact it cannot recall, exhausting the budget without committing to a final answer. We show this residual failure is reduced but not eliminated by the same edits, and argue it is fundamentally a knowledge-precision problem rather than a removable circuit; weight surgery can delete a loop, but it cannot supply a missing fact. Our results are both a feasibility demonstration, that is, evidence that a concrete generation pathology can be localized to a few parameters and edited out, and a delineation of where that approach stops.

Guidance is a crucial technique for extracting the best performance out of image-generating diffusion models. Traditionally, a constant guidance weight has been applied throughout the sampling chain of an image. We show that guidance is clearly harmful toward the beginning of the chain (high noise levels), largely unnecessary toward the end (low noise levels), and only beneficial in the middle. We thus restrict it to a specific range of noise levels, improving both the inference speed and result quality. This limited guidance interval improves the record FID in ImageNet-512 significantly, from 1.81 to 1.40. We show that it is quantitatively and qualitatively beneficial across different sampler parameters, network architectures, and datasets, including the large-scale setting of Stable Diffusion XL. We thus suggest exposing the guidance interval as a hyperparameter in all diffusion models that use guidance.

We revisit the problem of large-scale bundle adjustment and propose a technique called Multidirectional Conjugate Gradients that accelerates the solution of the normal equation by up to 61%. The key idea is that we enlarge the search space of classical preconditioned conjugate gradients to include multiple search directions. As a consequence, the resulting algorithm requires fewer iterations, leading to a significant speedup of large-scale reconstruction, in particular for denser problems where traditional approaches notoriously struggle. We provide a number of experimental ablation studies revealing the robustness to variations in the hyper-parameters and the speedup as a function of problem density.

In recent years, instruction-based image editing methods have garnered significant attention in image editing. However, despite encompassing a wide range of editing priors, these methods are helpless when handling editing tasks that are challenging to accurately describe through language. We propose InstructBrush, an inversion method for instruction-based image editing methods to bridge this gap. It extracts editing effects from exemplar image pairs as editing instructions, which are further applied for image editing. Two key techniques are introduced into InstructBrush, Attention-based Instruction Optimization and Transformation-oriented Instruction Initialization, to address the limitations of the previous method in terms of inversion effects and instruction generalization. To explore the ability of instruction inversion methods to guide image editing in open scenarios, we establish a TransformationOriented Paired Benchmark (TOP-Bench), which contains a rich set of scenes and editing types. The creation of this benchmark paves the way for further exploration of instruction inversion. Quantitatively and qualitatively, our approach achieves superior performance in editing and is more semantically consistent with the target editing effects.

When developing deep neural networks for segmenting intraoperative ultrasound images, several practical issues are encountered frequently, such as the presence of ultrasound frames that do not contain regions of interest and the high variance in ground-truth labels. In this study, we evaluate the utility of a pre-screening classification network prior to the segmentation network. Experimental results demonstrate that such a classifier, minimising frame classification errors, was able to directly impact the number of false positive and false negative frames. Importantly, the segmentation accuracy on the classifier-selected frames, that would be segmented, remains comparable to or better than those from standalone segmentation networks. Interestingly, the efficacy of the pre-screening classifier was affected by the sampling methods for training labels from multiple observers, a seemingly independent problem. We show experimentally that a previously proposed approach, combining random sampling and consensus labels, may need to be adapted to perform well in our application. Furthermore, this work aims to share practical experience in developing a machine learning application that assists highly variable interventional imaging for prostate cancer patients, to present robust and reproducible open-source implementations, and to report a set of comprehensive results and analysis comparing these practical, yet important, options in a real-world clinical application.

Text-guided image editing has seen rapid progress in natural image domains, but its adaptation to medical imaging remains limited and lacks standardized evaluation. Clinically, such editing holds promise for simulating surgical outcomes, creating personalized teaching materials, and enhancing patient communication. To bridge this gap, we introduce MedEBench, a comprehensive benchmark for evaluating text-guided medical image editing. It consists of 1,182 clinically sourced image-prompt triplets spanning 70 tasks across 13 anatomical regions. MedEBench offers three key contributions: (1) a clinically relevant evaluation framework covering Editing Accuracy, Contextual Preservation, and Visual Quality, supported by detailed descriptions of expected change and ROI (Region of Interest) masks; (2) a systematic comparison of seven state-of-the-art models, revealing common failure patterns; and (3) a failure analysis protocol based on attention grounding, using IoU between attention maps and ROIs to identify mislocalization. MedEBench provides a solid foundation for developing and evaluating reliable, clinically meaningful medical image editing systems.

The U-Net architecture and its variants have remained state-of-the-art (SOTA) for retinal vessel segmentation over the past decade. In this study, we introduce a Full-Scale Guided Network (FSG-Net), where a novel feature representation module using modernized convolution blocks effectively captures full-scale structural information, while a guided convolution block subsequently refines this information. Specifically, we introduce an attention-guided filter within the guided convolution block, leveraging its similarity to unsharp masking to enhance fine vascular structures. Passing full-scale information to the attention block facilitates the generation of more contextually relevant attention maps, which are then passed to the attention-guided filter, providing further refinement to the segmentation performance. The structure preceding the guided convolution block can be replaced by any U-Net variant, ensuring flexibility and scalability across various segmentation tasks. For a fair comparison, we re-implemented recent studies available in public repositories to evaluate their scalability and reproducibility. Our experiments demonstrate that, despite its compact architecture, FSG-Net delivers performance competitive with SOTA methods across multiple public datasets. Ablation studies further demonstrate that each proposed component meaningfully contributes to this competitive performance. Our code is available on https://github.com/ZombaSY/FSG-Net-pytorch.

Vision-language models, such as contrastive language-image pre-training (CLIP)-based approaches, have reached state-of-the-art (SOTA) results in medical artificial intelligence. However, recent work reveals that CLIP-based models remain vulnerable to shortcuts. We investigate how real-world shortcuts manifest across different layers of the medical CLIP-based model, MedCLIP, and its vision encoder, a frozen ResNet-50. We attach 17 linear classification probes to the intermediate layers of the ResNet-50 and train them on three different dataset configurations and targets: NIH-CXR14 (pneumothorax) and PadChest (cardiomegaly and pneumothorax). This setup allows us to observe model behaviour during evaluation using subgroup-based calibration and layer-wise confidence curves. We find that the final linear probes achieve a high AUROC but poor calibration in the models. The layer-wise confidence analyses suggest that shortcuts emerge at different depths. Patterns consistent with localised shortcuts, such as drains, appear at later layers, while patterns consistent with diffuse shortcuts, such as scanner-specific noise patterns, emerge earlier, aligning with previous work. Finally, we conduct a manual analysis of the images, which reveals data quality issues in both NIH-CXR14 and PadChest. Our findings underscore that even SOTA models remain vulnerable to shortcuts, and the need for high-quality and well-annotated datasets to draw solid conclusions. Code can be found on our GitHub: https://github.com/nikodice4/MedCLIP_shortcuts.

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its advantage of injecting the most up-to-date information, and researchers are focusing on understanding and improving this aspect to unlock the full potential of RAG in such high-stakes applications. However, despite the potential of RAG to address these needs, the mechanisms behind the confidence levels of its outputs remain underexplored, although the confidence of information is very critical in some domains, such as finance, healthcare, and medicine. Our study focuses the impact of RAG on confidence within the medical domain under various configurations and models. We evaluate confidence by treating the model's predicted probability as its output and calculating Expected Calibration Error (ECE) and Adaptive Calibration Error (ACE) scores based on the probabilities and accuracy. In addition, we analyze whether the order of retrieved documents within prompts calibrates the confidence. Our findings reveal large variation in confidence and accuracy depending on the model, settings, and the format of input prompts. These results underscore the necessity of optimizing configurations based on the specific model and conditions.

Specialist epilepsy expertise is scarce in resource-constrained settings, making LLM-based decision support attractive for frontline clinicians managing longitudinal treatment. Such systems must adapt to local prescribing practice and know when to defer. We study this problem in Ugandan pediatric epilepsy care, predicting anti-seizure medication regimens from longitudinal unstructured clinic notes. Standard prompting achieves non-trivial agreement with physician prescriptions, but neurologist review shows that many errors reflect distribution-miscalibrated prescribing defaults rather than failures to parse the local record. We introduce MANANA, a non-parametric prompt-learning framework that learns local prescribing guidance from a small patient-level training set. MANANA converts observed prescription errors into auditable prompt memories, instantiated in single-agent and multi-agent variants, and improves over classical ML models, direct LLM prompting, and prompt-optimization baselines across two independently collected Ugandan cohorts. We further propose Bayesian prompt averaging, which converts the learned prompt trajectory into prescription likelihoods and an uncertainty-based deferral signal. On the independently collected held-out cohort, this improves visit-level top-3 prescription accuracy by 4-8 percentage points over prompt-optimization baselines and enables selective prediction: the system can auto-handle the most confident half of cases at 95% precision, or the most confident quarter at 99% precision, while deferring lower-confidence cases for specialist review.

Text-guided diffusion models have significantly advanced image editing, enabling high-quality and diverse modifications driven by text prompts. However, effective editing requires inverting the source image into a latent space, a process often hindered by prediction errors inherent in DDIM inversion. These errors accumulate during the diffusion process, resulting in inferior content preservation and edit fidelity, especially with conditional inputs. We address these challenges by investigating the primary contributors to error accumulation in DDIM inversion and identify the singularity problem in traditional noise schedules as a key issue. To resolve this, we introduce the Logistic Schedule, a novel noise schedule designed to eliminate singularities, improve inversion stability, and provide a better noise space for image editing. This schedule reduces noise prediction errors, enabling more faithful editing that preserves the original content of the source image. Our approach requires no additional retraining and is compatible with various existing editing methods. Experiments across eight editing tasks demonstrate the Logistic Schedule's superior performance in content preservation and edit fidelity compared to traditional noise schedules, highlighting its adaptability and effectiveness.

Intraoperative pathology is pivotal to precision surgery, yet its clinical impact is constrained by diagnostic complexity and the limited availability of high-quality frozen-section data. While computational pathology has made significant strides, the lack of large-scale, prospective validation has impeded its routine adoption in surgical workflows. Here, we introduce CRISP, a clinical-grade foundation model developed on over 100,000 frozen sections from eight medical centers, specifically designed to provide Clinical-grade Robust Intraoperative Support for Pathology (CRISP). CRISP was comprehensively evaluated on more than 15,000 intraoperative slides across nearly 100 retrospective diagnostic tasks, including benign-malignant discrimination, key intraoperative decision-making, and pan-cancer detection, etc. The model demonstrated robust generalization across diverse institutions, tumor types, and anatomical sites-including previously unseen sites and rare cancers. In a prospective cohort of over 2,000 patients, CRISP sustained high diagnostic accuracy under real-world conditions, directly informing surgical decisions in 92.6% of cases. Human-AI collaboration further reduced diagnostic workload by 35%, avoided 105 ancillary tests and enhanced detection of micrometastases with 87.5% accuracy. Together, these findings position CRISP as a clinical-grade paradigm for AI-driven intraoperative pathology, bridging computational advances with surgical precision and accelerating the translation of artificial intelligence into routine clinical practice.

Mechanism-targeted synthetic data is increasingly proposed as a way to steer pretraining toward desirable capabilities, but it remains unclear how such interventions should be evaluated. We study this question for in-context learning (ICL) under matched compute (iso-FLOPs) using Bi-Induct, a lightweight data rewrite that interleaves short directional copy snippets into a natural pretraining stream: forward-copy (induction), backward-copy (anti-induction, as a directional control), or a balanced mix. Across 0.13B-1B decoder-only models, we evaluate (i) few-shot performance on standard LM benchmarks and function-style ICL probes, (ii) head-level copy telemetry, and (iii) held-out perplexity as a guardrail. Bi-Induct reliably increases induction-head activity, but this does not translate into consistent improvements in few-shot generalization: on standard LM benchmarks, Bi-Induct is largely performance-neutral relative to natural-only training, while on function-style probes the 1B natural-only model performs best. Despite explicit backward-copy cues, anti-induction scores remain near zero across scales, revealing a strong forward/backward asymmetry. Targeted ablations show a sharper distinction: removing the top 2% induction heads per layer harms ICL more than matched random ablations, with the largest relative drop occurring in the natural-only models. This indicates that natural-only training produces more centralized, load-bearing induction circuitry, whereas Bi-Induct tends to create more distributed and redundant induction activity. Our main conclusion is that eliciting a mechanism is not the same as making it load-bearing. For data-centric foundation model design, this suggests that synthetic data interventions should be evaluated not only by signature amplification, but by whether they create causally necessary computation while preserving natural-data modeling quality.

In-context learning (ICL) allows LLMs to learn from examples without changing their weights, which is a particularly promising capability for long-context LLMs that can potentially learn from many examples. Recently, Lin et al. (2024) proposed URIAL, a method using only three in-context examples to align base LLMs, achieving non-trivial instruction following performance. In this work, we show that, while effective, ICL alignment with URIAL still underperforms compared to instruction fine-tuning on established benchmarks such as MT-Bench and AlpacaEval 2.0 (LC), especially with more capable base LMs. Unlike for tasks such as classification, translation, or summarization, adding more ICL demonstrations for long-context LLMs does not systematically improve instruction following performance. To address this limitation, we derive a greedy selection approach for ICL examples that noticeably improves performance, yet without bridging the gap to instruction fine-tuning. Finally, we provide a series of ablation studies to better understand the reasons behind the remaining gap, and we show how some aspects of ICL depart from the existing knowledge and are specific to the instruction tuning setting. Overall, our work advances the understanding of ICL as an alignment technique. We provide our code at https://github.com/tml-epfl/icl-alignment.

This paper investigates using knowledge editing techniques to detoxify Large Language Models (LLMs). We construct a benchmark, SafeEdit, which covers nine unsafe categories with various powerful attack prompts and equips comprehensive metrics for systematic evaluation. We conduct experiments to compare knowledge editing approaches with previous baselines, indicating that knowledge editing has the potential to efficiently detoxify LLMs with limited impact on general performance. Then, we propose a simple yet effective baseline, dubbed Detoxifying with Intraoperative Neural Monitoring (DINM), to diminish the toxicity of LLMs within a few tuning steps via only one instance. We further provide an in-depth analysis of the internal mechanism for various detoxify approaches, demonstrating that previous methods like SFT and DPO may merely suppress the activations of toxic parameters, while DINM mitigates the toxicity of the toxic parameters to a certain extent, making permanent adjustments. We hope that these insights could shed light on future work of developing detoxifying approaches and the underlying knowledge mechanisms of LLMs. Code and benchmark are available at https://github.com/zjunlp/EasyEdit.

Electroencephalography (EEG) is a cornerstone of brain-computer interfaces and clinical neuroscience, yet deep learning models are typically trained and evaluated under a single, unreported preprocessing pipeline. We formalize preprocessing choices as a counterfactual intervention space and show that EEG predictions are surprisingly unstable under this space: across six datasets spanning four paradigms, up to 42% of trial-level predictions flip when only the preprocessing changes, a variability that standard uncertainty methods do not explicitly quantify because they condition on a fixed preprocessing pipeline. We provide three tools to make this instability measurable, decomposable, and reducible. First, a Walsh-Hadamard decomposition of the 2^7 pipeline space reveals that sensitivity is near-additive in practice under the binary intervention design, enabling efficient step-by-step optimization. Second, we introduce Preprocessing Uncertainty (PU), a per-trial diagnostic that captures a dimension of instability complementary to model-based confidence. Third, we study Normalized Adaptive PGI (NA-PGI), a graph-structured regularizer that exploits the compositional structure of preprocessing interventions as one mitigation strategy with clear scope conditions.

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen target domains. Recently, the segment anything model (SAM) has demonstrated strong generalization capabilities due to its prompt-based design, and has gained significant attention in image segmentation tasks. Existing SAM-based approaches attempt to address the need for manual prompts by introducing prompt generators that automatically generate these prompts. However, we argue that auto-generated prompts may not be sufficiently accurate under distribution shifts, potentially leading to incorrect predictions that still require manual verification and correction by clinicians. To address this challenge, we propose a method for 2D medical image segmentation called Self-Correcting SAM (CoSAM). Our approach begins by generating coarse masks using SAM in a prompt-free manner, providing prior prompts for the subsequent stages, and eliminating the need for prompt generators. To automatically refine these coarse masks, we introduce a generalized error decoder that simulates the correction process typically performed by clinicians. Furthermore, we generate diverse prompts as feedback based on the corrected masks, which are used to iteratively refine the predictions within a self-correcting loop, enhancing the generalization performance of our model. Extensive experiments on two medical image segmentation benchmarks across multiple scenarios demonstrate the superiority of CoSAM over state-of-the-art SAM-based methods.

The diffusion model presents a powerful ability to capture the entire (conditional) data distribution. However, due to the lack of sufficient training and data to learn to cover low-probability areas, the model will be penalized for failing to generate high-quality images corresponding to these areas. To achieve better generation quality, guidance strategies such as classifier free guidance (CFG) can guide the samples to the high-probability areas during the sampling stage. However, the standard CFG often leads to over-simplified or distorted samples. On the other hand, the alternative line of guiding diffusion model with its bad version is limited by carefully designed degradation strategies, extra training and additional sampling steps. In this paper, we proposed a simple yet effective strategy Internal Guidance (IG), which introduces an auxiliary supervision on the intermediate layer during training process and extrapolates the intermediate and deep layer's outputs to obtain generative results during sampling process. This simple strategy yields significant improvements in both training efficiency and generation quality on various baselines. On ImageNet 256x256, SiT-XL/2+IG achieves FID=5.31 and FID=1.75 at 80 and 800 epochs. More impressively, LightningDiT-XL/1+IG achieves FID=1.34 which achieves a large margin between all of these methods. Combined with CFG, LightningDiT-XL/1+IG achieves the current state-of-the-art FID of 1.19.

Reliable rubric grading requires more than accurate score prediction. Each judgement must be grounded in the mark scheme and evidence from the student answer. Existing credit-assignment and intervention methods, primarily designed for self-contained reasoning tasks such as mathematics reasoning, struggle in this setting because they do not identify where grading reasoning goes wrong or how the model's belief about the final mark changes during reasoning. We propose Evidence-Diagnosed Intervention Training (EDIT), a two-phase framework for training more rubric-faithful LLM graders. First, EDIT-SFT locates problematic reasoning steps using internal model signals: posterior belief over the final mark and input-grounding scores. It then revises only these local steps with help from a rubric checklist. Second, EDIT-RL calibrates the grader with belief-guided reward shaping, penalising large harmful belief drifts while still allowing helpful exploration. Experiments on two real-world, multi-subject grading benchmarks demonstrate that EDIT consistently outperforms strong supervised fine-tuning and reinforcement learning baselines on both in-domain and out-of-domain splits, with ablation studies confirming that internal-state diagnostics drive these gains.

Surgical scene segmentation is critical in computer-assisted surgery and is vital for enhancing surgical quality and patient outcomes. Recently, referring surgical segmentation is emerging, given its advantage of providing surgeons with an interactive experience to segment the target object. However, existing methods are limited by low efficiency and short-term tracking, hindering their applicability in complex real-world surgical scenarios. In this paper, we introduce ReSurgSAM2, a two-stage surgical referring segmentation framework that leverages Segment Anything Model 2 to perform text-referred target detection, followed by tracking with reliable initial frame identification and diversity-driven long-term memory. For the detection stage, we propose a cross-modal spatial-temporal Mamba to generate precise detection and segmentation results. Based on these results, our credible initial frame selection strategy identifies the reliable frame for the subsequent tracking. Upon selecting the initial frame, our method transitions to the tracking stage, where it incorporates a diversity-driven memory mechanism that maintains a credible and diverse memory bank, ensuring consistent long-term tracking. Extensive experiments demonstrate that ReSurgSAM2 achieves substantial improvements in accuracy and efficiency compared to existing methods, operating in real-time at 61.2 FPS. Our code and datasets will be available at https://github.com/jinlab-imvr/ReSurgSAM2.

Text-guided image editors can now manipulate authentic medical scans with high fidelity, enabling lesion implantation/removal that threatens clinical trust and safety. Existing defenses are inadequate for healthcare. Medical detectors are largely black-box, while MLLM-based explainers are typically post-hoc, lack medical expertise, and may hallucinate evidence on ambiguous cases. We present MedForge, a data-and-method solution for pre-hoc, evidence-grounded medical forgery detection. We introduce MedForge-90K, a large-scale benchmark of realistic lesion edits across 19 pathologies with expert-guided reasoning supervision via doctor inspection guidelines and gold edit locations. Building on it, MedForge-Reasoner performs localize-then-analyze reasoning, predicting suspicious regions before producing a verdict, and is further aligned with Forgery-aware GSPO to strengthen grounding and reduce hallucinations. Experiments demonstrate state-of-the-art detection accuracy and trustworthy, expert-aligned explanations.

Conditional diffusion and flow models routinely fail to satisfy the very constraints that define their task. For instance, a depth-conditioned model often produces images whose re-extracted depth disagrees with the input, even though the forward operator--the depth predictor defining the constraint--is available during both training and inference. Existing approaches generally fall into two categories: supervised models that treat the conditioning signal as a static cue and ignore alignment information at inference, and guidance-based methods that consult it through hand-tuned linear updates, typically trading fidelity to the condition against the plausibility of the generated sample. We argue that the fundamental gap in both paradigms is that the model is never trained to utilize its own alignment error. We introduce FlowBender, a closed-loop framework that treats this error as a first-class input, training the network to learn a correction policy conditioned on inference-time feedback. At each step, an unguided look-ahead pass estimates the clean signal, a task-specific deviation is computed via the forward operator, and a refinement pass consumes this signal to produce a corrected velocity. We propose several variants of FlowBender, including a gradient-based formulation for differentiable operators and a zero-order variant for non-differentiable settings such as JPEG compression. For efficient sampling, we introduce a prior-step shortcut that enables closed-loop correction at a minimal additional computational cost. Across image-to-image translation, restoration, and 3D mesh texturing, FlowBender consistently outperforms standard supervised baselines, alignment-loss-augmented training, and state-of-the-art inference-time guidance, improving fidelity and plausibility simultaneously rather than trading them against each other. Project page: https://flow-bender.github.io/

Coronary microvascular dysfunction (CMD), characterized by impaired regulation of blood flow in the coronary microcirculation, plays a key role in the pathogenesis of ischemic heart disease and is increasingly recognized as a contributor to adverse cardiovascular outcomes. Despite its clinical importance, CMD remains underdiagnosed due to the reliance on invasive procedures such as pressure wire-based measurements of the index of microcirculatory resistance (IMR) and coronary flow reserve (CFR), which are costly, time-consuming, and carry procedural risks. To date, no study has sought to quantify CMD indices using data-driven approaches while leveraging the rich information contained in coronary angiograms. To address these limitations, this study proposes a novel data-driven framework for inference of CMD indices based on coronary angiography. A physiologically validated multi-physics model was used to generate synthetic datasets for data-driven model training, consisting of CMD indices and computational angiograms with corresponding contrast intensity profiles (CIPs). Two neural network architectures were developed: a single-input-channel encoder-MLP model for IMR prediction and a dual-input-channel encoder-MLP model for CFR prediction, both incorporating epistemic uncertainty estimation to quantify prediction confidence. Results demonstrate that the data-driven models achieve high predictive accuracy when evaluated against physics-based synthetic datasets, and that the uncertainty estimates are positively correlated with prediction errors. Furthermore, the utility of CIPs as informative surrogates for coronary physiology is demonstrated, underscoring the potential of the proposed framework to enable accurate, real-time, image-based CMD assessment using routine angiography without the need for more invasive approaches.

Many-shot in-context learning has recently shown promise as an alternative to finetuning, with the major advantage that the same model can be served for multiple tasks. However, this shifts the computational burden from training-time to inference-time, making deployment of many-shot ICL challenging to justify in-practice. This cost is further increased if a custom demonstration set is retrieved for each inference example. We present Dynamic Block-Sparse Attention, a training-free framework for retrieval-based many-shot in-context learning. By combining carefully designed block-sparse attention and retrieval of cached groups of demonstrations, we achieve comparable per-example latency to finetuning while maintaining on average >95% of the best method's accuracy across strong ICL and finetuning baselines. We hope that this will further enable the deployment of many-shot ICL at scale.

While large language models (LLMs) have demonstrated remarkable performance across diverse tasks, they fundamentally lack self-awareness and frequently exhibit overconfidence, assigning high confidence scores to incorrect predictions. Accurate confidence estimation is therefore critical for enhancing the trustworthiness and reliability of LLM-generated outputs. However, existing approaches suffer from coarse-grained scoring mechanisms that fail to provide fine-grained, continuous confidence estimates throughout the generation process. To address these limitations, we introduce FineCE, a novel confidence estimation method that delivers accurate, fine-grained confidence scores during text generation. Specifically, we first develop a comprehensive pipeline for constructing training data that effectively captures the underlying probabilistic distribution of LLM responses, and then train a model to predict confidence scores for arbitrary text sequences in a supervised manner. Furthermore, we propose a Backward Confidence Integration (BCI) strategy that leverages information from the subsequent text to enhance confidence estimation for the current sequence during inference. We also introduce three strategies for identifying optimal positions to perform confidence estimation within the generation process. Extensive experiments on multiple benchmark datasets demonstrate that FineCE consistently outperforms existing classical confidence estimation methods. Our code and all baselines used in the paper are available on GitHub.

ASR Error Detection (AED) models aim to post-process the output of Automatic Speech Recognition (ASR) systems, in order to detect transcription errors. Modern approaches usually use text-based input, comprised solely of the ASR transcription hypothesis, disregarding additional signals from the ASR model. Instead, we propose to utilize the ASR system's word-level confidence scores for improving AED performance. Specifically, we add an ASR Confidence Embedding (ACE) layer to the AED model's encoder, allowing us to jointly encode the confidence scores and the transcribed text into a contextualized representation. Our experiments show the benefits of ASR confidence scores for AED, their complementary effect over the textual signal, as well as the effectiveness and robustness of ACE for combining these signals. To foster further research, we publish a novel AED dataset consisting of ASR outputs on the LibriSpeech corpus with annotated transcription errors.

Vision-language models (VLMs) are increasingly augmented with continuous or latent non-textual tokens intended to support "visual thinking." Despite improved task accuracy, this alone does not show that models actually use these tokens for reasoning -- gains may arise from confounds such as added context length, special-token anchoring, or training-time regularization. We formalize a diagnostic principle, Ablate-to-Validate, for testing whether latent-token content is genuinely utilized, and instantiate it as the Token Replacement Test (TRT), a standardized suite of content-replacement ablations. TRT holds the prompt, image, token budget, and decoding fixed while replacing intermediate tokens with zero, random, first-repeat, or oracle alternatives, isolating whether performance depends on token content or merely on token presence. As a controlled testbed, we study relative depth reasoning with LLaVA-13B and Qwen2.5-VL-3B, training models to predict and consume continuous or discrete depth spans across multiple frozen encoders (SigLIP2, CLIP, DINOv2) and token budgets. We additionally apply TRT to three off-the-shelf visual-thinking systems (Mirage, Mull-Tokens, CoVT) on BLINK, VSP, and CV-Bench. Across all settings, accuracy gains are a misleading proxy for latent-token reasoning: VLMs retain most improvement even when token content is corrupted or replaced, revealing a persistent gap between having a latent channel and using it as an information bottleneck. We recommend TRT as a standard diagnostic alongside accuracy for any method introducing continuous thought tokens.

Block Diffusion Models (BDMs) support parallel generation, flexible-length output, and KV caching, making them promising for efficient document parsing. However, existing BDMs bind denoising and cache commitment to fixed block boundaries: parallelism shrinks during intra-block denoising, while generated tokens cannot be cached until the whole block is completed. Moreover, intra-block bidirectional denoising conflicts with inter-block autoregression, creating inconsistent information flow that can challenge structure-sensitive recognition. We propose the Prefix-Adaptive Block Diffusion Model (PA-BDM), which replaces intra-block bidirectional denoising with causal denoising from prefix to suffix and treats the block size as a maximum candidate range rather than a fixed commitment unit. PA-BDM uses Confidence-gated Structural Loss (CSL) to build low-entropy prefixes before extending training to longer continuations. During inference, Progressive Prefix Commitment (PPC) then dynamically commits the longest reliable prefix into the KV cache and resets the next candidate range from the updated prefix, restoring a large parallel decoding space at each step. Experiments show that the 3B PA-BDM achieves higher recognition scores on several benchmarks and improves inference throughput by 71.6\% over the 2.5B MinerU-Diffusion.

Large language models (LLMs) are increasingly used in applications requiring factual accuracy, yet their outputs often contain hallucinated responses. While fact-checking can mitigate these errors, existing methods typically retrieve external evidence indiscriminately, overlooking the model's internal knowledge and potentially introducing irrelevant noise. Moreover, current systems lack targeted mechanisms to resolve specific uncertainties in the model's reasoning. Inspired by how humans fact-check, we argue that LLMs should adaptively decide whether to rely on internal knowledge or initiate retrieval based on their confidence in a given claim. We introduce Probabilistic Certainty and Consistency (PCC), a framework that estimates factual confidence by jointly modeling an LLM's probabilistic certainty and reasoning consistency. These confidence signals enable an adaptive verification strategy: the model answers directly when confident, triggers targeted retrieval when uncertain or inconsistent, and escalates to deep search when ambiguity is high. Our confidence-guided routing mechanism ensures that retrieval is invoked only when necessary, improving both efficiency and reliability. Extensive experiments across three challenging benchmarks show that PCC achieves better uncertainty quantification than verbalized confidence and consistently outperforms strong LLM-based fact-checking baselines. Furthermore, we demonstrate that PCC generalizes well across various LLMs.

Diffusion models have demonstrated superior performance across various generative tasks including images, videos, and audio. However, they encounter difficulties in directly generating high-resolution samples. Previously proposed solutions to this issue involve modifying the architecture, further training, or partitioning the sampling process into multiple stages. These methods have the limitation of not being able to directly utilize pre-trained models as-is, requiring additional work. In this paper, we introduce upsample guidance, a technique that adapts pretrained diffusion model (e.g., 512^2) to generate higher-resolution images (e.g., 1536^2) by adding only a single term in the sampling process. Remarkably, this technique does not necessitate any additional training or relying on external models. We demonstrate that upsample guidance can be applied to various models, such as pixel-space, latent space, and video diffusion models. We also observed that the proper selection of guidance scale can improve image quality, fidelity, and prompt alignment.

Reliable uncertainty estimation is critical for medical image segmentation, where automated contours feed downstream quantification and clinical decision support. Many strong uncertainty methods require repeated inference, while efficient single-forward-pass alternatives often provide weaker failure ranking or rely on restrictive feature-space assumptions. We present SegWithU, a post-hoc framework that augments a frozen pretrained segmentation backbone with a lightweight uncertainty head. SegWithU taps intermediate backbone features and models uncertainty as perturbation energy in a compact probe space using rank-1 posterior probes. It produces two voxel-wise uncertainty maps: a calibration-oriented map for probability tempering and a ranking-oriented map for error detection and selective prediction. Across ACDC, BraTS2024, and LiTS, SegWithU is the strongest and most consistent single-forward-pass baseline, achieving AUROC/AURC of 0.9838/2.4885, 0.9946/0.2660, and 0.9925/0.8193, respectively, while preserving segmentation quality. These results suggest that perturbation-based uncertainty modeling is an effective and practical route to reliability-aware medical segmentation. Source code is available at https://github.com/ProjectNeura/SegWithU.

Semi-supervised semantic segmentation has long turned on one question, which pseudo-labels to trust, and a generation of selection rules, dynamic thresholds, per-class curricula, soft confidence weights, answered it for the noisy, under-confident ResNet teachers of their day. Self-supervised foundation encoders change the regime: with a DINOv2 teacher, confidence saturates, so the filtering that helped a weak teacher can hurt a strong one. We propose CW-BASS v2, a saturation-aware pseudo-label selection method that reads the teacher's confidence regime rather than committing to one rule. It pairs held-out calibration, an unbiased per-class noise estimate, with a self-adaptive confidence floor that provably bounds retention away from 1, and combines them in a one-pass gate: measure the reliability of the teacher's confident set, pi_kept = Pr[correct | c >= tau], on a held-out slice, and filter strictly when it meets the confidence demanded (pi_kept >= tau), falling back to the adaptive floor otherwise. The boundary is the pre-existing operating threshold, not a value tuned to mIoU, and across six DINOv2 teachers it makes the correct strict-vs-floor call blind. CW-BASS v2 thus recovers the UniMatch V2 operating point on the saturated benchmarks by selecting strict (Pascal VOC 1/8 87.4 against its reported 87.9; Cityscapes within 0.5), and improves on it where the confident set is unreliable (pi_kept ~ 89%, ADE20K), where the floor edges ahead (+1.5 mIoU, single seed). The gate is principled because the failure it avoids is measured, not assumed: on a reliable, saturated teacher the confidence distribution's dynamic range collapses (98% of Pascal pixels >= 0.95), so an adaptive cutoff floods the retention mask and self-training decays into confirmation bias.

Instruction-based image editing enables robust image modification via natural language prompts, yet current methods face a precision-efficiency tradeoff. Fine-tuning methods demand significant computational resources and large datasets, while training-free techniques struggle with instruction comprehension and edit quality. We resolve this dilemma by leveraging large-scale Diffusion Transformer (DiT)' enhanced generation capacity and native contextual awareness. Our solution introduces three contributions: (1) an in-context editing framework for zero-shot instruction compliance using in-context prompting, avoiding structural changes; (2) a LoRA-MoE hybrid tuning strategy that enhances flexibility with efficient adaptation and dynamic expert routing, without extensive retraining; and (3) an early filter inference-time scaling method using vision-language models (VLMs) to select better initial noise early, improving edit quality. Extensive evaluations demonstrate our method's superiority: it outperforms state-of-the-art approaches while requiring only 0.5% training data and 1% trainable parameters compared to conventional baselines. This work establishes a new paradigm that enables high-precision yet efficient instruction-guided editing. Codes and demos can be found in https://river-zhang.github.io/ICEdit-gh-pages/.

Block-diffusion language models offer a promising path toward faster-than-autoregressive generation by combining block-wise autoregressive decoding with within-block parallel denoising. However, in the few-step regime needed for practical acceleration, standard confidence-thresholded decoding is often brittle: aggressive thresholds hurt quality, while conservative thresholds require unnecessary denoising steps. Existing approaches that address this issue either require additional training or incur extra test-time compute. We present S2D2, a training-free self-speculative decoding framework for block-diffusion language models. Our key observation is that a block-diffusion model becomes autoregressive when the block size is reduced to one, allowing the same pretrained model to act as both drafter and verifier. S2D2 inserts a speculative verification step into standard block-diffusion decoding and uses lightweight routing policies to decide when verification is worth its cost. This yields a hybrid decoding trajectory in which diffusion proposes tokens in parallel, while the autoregressive mode acts as a local sequence-level critic. Across three mainstream block-diffusion families, S2D2 consistently improves the accuracy-speed tradeoff over strong confidence-thresholding baselines. On SDAR, we observe up to 4.7times speedup over autoregressive decoding, and up to 1.57times over a tuned dynamic decoding baseline while improving accuracy by up to 4.5 points. On LLaDA2.1-Mini, S2D2 remains complementary to built-in self-correction, including a conservative setting where it is 4.4times faster than the static baseline with slightly higher accuracy.

Despite recent advances in diffusion models, achieving reliable image generation and editing remains challenging due to the inherent diversity induced by stochastic noise in the sampling process. Instruction-guided image editing with diffusion models offers user-friendly capabilities, yet editing failures, such as background distortion, frequently occur. Users often resort to trial and error, adjusting seeds or prompts to achieve satisfactory results, which is inefficient. While seed selection methods exist for Text-to-Image (T2I) generation, they depend on external verifiers, limiting applicability, and evaluating multiple seeds increases computational complexity. To address this, we first establish a multiple-seed-based image editing baseline using background consistency scores, achieving Best-of-N performance without supervision. Building on this, we introduce ELECT (Early-timestep Latent Evaluation for Candidate Selection), a zero-shot framework that selects reliable seeds by estimating background mismatches at early diffusion timesteps, identifying the seed that retains the background while modifying only the foreground. ELECT ranks seed candidates by a background inconsistency score, filtering unsuitable samples early based on background consistency while preserving editability. Beyond standalone seed selection, ELECT integrates into instruction-guided editing pipelines and extends to Multimodal Large-Language Models (MLLMs) for joint seed and prompt selection, further improving results when seed selection alone is insufficient. Experiments show that ELECT reduces computational costs (by 41 percent on average and up to 61 percent) while improving background consistency and instruction adherence, achieving around 40 percent success rates in previously failed cases - without any external supervision or training.

Current motion-controlled image-to-video generation models rigidly follow user-provided trajectories that are often sparse, imprecise, and causally incomplete. Such reliance often yields unnatural or implausible outcomes, especially by missing secondary causal consequences. To address this, we introduce MotiMotion, a novel framework that reformulates motion control as a reasoning-then-generation problem. To encourage causally grounded and commonsense-consistent interactions, we leverage a training-free vision-language reasoner to refine image-space coordinates of primary trajectories and to hallucinate plausible secondary motions. To further improve motion naturalness, we propose a confidence-aware control scheme that modulates guidance strength, enabling the model to closely follow high-confidence plans while correcting artifacts under low-confidence inputs with its internal generative priors. To support systematic evaluation, we curate a new image-to-video benchmark, MotiBench, consisting of interaction-centric scenes where new events are triggered by motion. Both VLM-based evaluation and a human study on MotiBench demonstrate that MotiMotion produces videos with more plausible object behaviors and interaction, and is preferred over existing approaches.

We introduce CADE 2.5 (Comfy Adaptive Detail Enhancer), a sampler-level guidance stack for SD/SDXL latent diffusion models. The central module, ZeResFDG, unifies (i) frequency-decoupled guidance that reweights low- and high-frequency components of the guidance signal, (ii) energy rescaling that matches the per-sample magnitude of the guided prediction to the positive branch, and (iii) zero-projection that removes the component parallel to the unconditional direction. A lightweight spectral EMA with hysteresis switches between a conservative and a detail-seeking mode as structure crystallizes during sampling. Across SD/SDXL samplers, ZeResFDG improves sharpness, prompt adherence, and artifact control at moderate guidance scales without any retraining. In addition, we employ a training-free inference-time stabilizer, QSilk Micrograin Stabilizer (quantile clamp + depth/edge-gated micro-detail injection), which improves robustness and yields natural high-frequency micro-texture at high resolutions with negligible overhead. For completeness we note that the same rule is compatible with alternative parameterizations (e.g., velocity), which we briefly discuss in the Appendix; however, this paper focuses on SD/SDXL latent diffusion models.

Medical visual question answering (Med-VQA) aims to answer clinically relevant questions grounded in medical images. However, existing multimodal large language models (MLLMs) often exhibit shortcut answering, producing plausible responses by exploiting language priors or dataset biases while insufficiently attending to visual evidence. This behavior undermines clinical reliability, especially when subtle imaging findings are decisive. We propose a lightweight plug-in framework, termed Intent-aware Visual Cues (InViC), to explicitly enhance image-based answer generation in medical VQA. InViC introduces a Cue Tokens Extraction (CTE) module that distills dense visual tokens into a compact set of K question-conditioned cue tokens, which serve as structured visual intermediaries injected into the LLM decoder to promote intent-aligned visual evidence. To discourage bypassing of visual information, we further design a two-stage fine-tuning strategy with a cue-bottleneck attention mask. In Stage I, we employ an attention mask to block the LLM's direct view of raw visual features, thereby funneling all visual evidence through the cue pathway. In Stage II, standard causal attention is restored to train the LLM to jointly exploit the visual and cue tokens. We evaluate InViC on three public Med-VQA benchmarks (VQA-RAD, SLAKE, and ImageCLEF VQA-Med 2019) across multiple representative MLLMs. InViC consistently improves over zero-shot inference and standard LoRA fine-tuning, demonstrating that intent-aware visual cues with bottlenecked training is a practical and effective strategy for improving trustworthy Med-VQA.

When using a diffusion model for image editing, there are times when the modified image can differ greatly from the source. To address this, we apply a dual-guidance approach to maintain high fidelity to the original in areas that are not altered. First, we employ text-guided optimization, using text embeddings to direct latent space and classifier-free guidance. Second, we use perceptual similarity guidance, optimizing latent vectors with posterior sampling via Tweedie formula during the reverse process. This method ensures the realistic rendering of both the edited elements and the preservation of the unedited parts of the original image.

Biomedical imaging datasets are often small and biased, meaning that real-world performance of predictive models can be substantially lower than expected from internal testing. This work proposes using generative image editing to simulate dataset shifts and diagnose failure modes of biomedical vision models; this can be used in advance of deployment to assess readiness, potentially reducing cost and patient harm. Existing editing methods can produce undesirable changes, with spurious correlations learned due to the co-occurrence of disease and treatment interventions, limiting practical applicability. To address this, we train a text-to-image diffusion model on multiple chest X-ray datasets and introduce a new editing method RadEdit that uses multiple masks, if present, to constrain changes and ensure consistency in the edited images. We consider three types of dataset shifts: acquisition shift, manifestation shift, and population shift, and demonstrate that our approach can diagnose failures and quantify model robustness without additional data collection, complementing more qualitative tools for explainable AI.

Intraoperative registration of real-time ultrasound (iUS) to preoperative Magnetic Resonance Imaging (MRI) remains an unsolved problem due to severe modality-specific differences in appearance, resolution, and field-of-view. To address this, we propose a novel 3D cross-modal keypoint descriptor for MRI-iUS matching and registration. Our approach employs a patient-specific matching-by-synthesis approach, generating synthetic iUS volumes from preoperative MRI. This enables supervised contrastive training to learn a shared descriptor space. A probabilistic keypoint detection strategy is then employed to identify anatomically salient and modality-consistent locations. During training, a curriculum-based triplet loss with dynamic hard negative mining is used to learn descriptors that are i) robust to iUS artifacts such as speckle noise and limited coverage, and ii) rotation-invariant. At inference, the method detects keypoints in MR and real iUS images and identifies sparse matches, which are then used to perform rigid registration. Our approach is evaluated using 3D MRI-iUS pairs from the ReMIND dataset. Experiments show that our approach outperforms state-of-the-art keypoint matching methods across 11 patients, with an average precision of 69.8%. For image registration, our method achieves a competitive mean Target Registration Error of 2.39 mm on the ReMIND2Reg benchmark. Compared to existing iUS-MR registration approaches, our framework is interpretable, requires no manual initialization, and shows robustness to iUS field-of-view variation. Code, data and model weights are available at https://github.com/morozovdd/CrossKEY.

Existing optical flow methods broadly follow two paradigms: iterative optimization and diffusion-based estimation. Iterative methods, exemplified by RAFT, achieve high accuracy through recurrent refinement, but remain challenged by large displacements and complex motion. Diffusion-based methods introduce generative modeling and show promise in such ambiguous regions. However, existing diffusion models usually denoise the entire dense flow field from Gaussian noise, including simple regions where reliable motion can already be estimated by a lightweight network. This increases the denoising burden and may cause slow convergence and unstable training. To address this issue, we introduce FlowPainter, a diffusion-based optical flow framework that reformulates dense-flow generation as confidence-guided soft inpainting. FlowPainter employs a lightweight confidence-aware network to predict a rough flow and a pixel-wise confidence mask, distinguishing reliable simple regions from uncertain hard regions. The resulting simple-flow prior is used for confidence-based initialization and further injected into iterative denoising through confidence-gated residual guidance. With dynamically decaying guidance strength, FlowPainter stabilizes early denoising while preserving the flexibility of the diffusion model for late-stage detail refinement. Extensive experiments on public benchmarks, including Sintel, KITTI, and Spring, show that FlowPainter achieves strong accuracy under comparable training settings and converges more efficiently than existing diffusion-based optical flow methods, with notable gains on challenging benchmark splits. Our approach offers a practical way to integrate reliable discriminative priors with diffusion-based refinement for optical flow estimation. Our code is publicly available at https://github.com/mya012/FlowPainter.

Coarse-guided visual generation, which synthesizes fine visual samples from degraded or low-fidelity coarse references, is essential for various real-world applications. While training-based approaches are effective, they are inherently limited by high training costs and restricted generalization due to paired data collection. Accordingly, recent training-free works propose to leverage pretrained diffusion models and incorporate guidance during the sampling process. However, these training-free methods either require knowing the forward (fine-to-coarse) transformation operator, e.g., bicubic downsampling, or are difficult to balance between guidance and synthetic quality. To address these challenges, we propose a novel guided method by using the h-transform, a tool that can constrain stochastic processes (e.g., sampling process) under desired conditions. Specifically, we modify the transition probability at each sampling timestep by adding to the original differential equation with a drift function, which approximately steers the generation toward the ideal fine sample. To address unavoidable approximation errors, we introduce a noise-level-aware schedule that gradually de-weights the term as the error increases, ensuring both guidance adherence and high-quality synthesis. Extensive experiments across diverse image and video generation tasks demonstrate the effectiveness and generalization of our method.

Interactive egocentric medical image segmentation (IEMIS) plays an important role in smart-glasses-assisted medical image review, segmenting the medical targets a clinician refers to from their egocentric view. Once it succeeds, the object-level visual evidence it provides strengthens the review and underpins fine-grained analysis and clinical decision-making. However, the instruction and the video both come from the user's egocentric perspective, which poses two challenges. (1) Semantic ambiguity leaves the model unable to confirm the user-intended target. (2) Visual variability makes the segmentation jump from frame to frame. In this paper, we propose EgoMed-Agent, a multi-agent system that understands the target from the human perspective through two workflows. (1) The Target Confirmation Workflow grounds the instruction against candidate targets with a reliability score, confirming the target when the grounding is reliable and asking the user to clarify when it is not, thereby confirming the segmentation target. (2) The Localization-Guided Propagation Workflow couples mask propagation with per-frame target localization, using the localized target to correct the propagated mask whenever the two diverge, so the segmentation stays on the target across the egocentric video. Extensive experiments show that EgoMed-Agent reaches 71.34\% average Dice, far above the best text-prompted baseline (11.70\%). Our code is available at https://github.com/wdyyyyyy/EgoMed-Agent{our project page}.

Diffusion large language models promise parallel token generation, yet inference remains bottlenecked by deciding which masked tokens can be safely committed together. Fast-dLLM addressed this with KV caching and confidence-guided parallel decoding, but its decoding theory uses a homogeneous high-confidence assumption that effectively reduces each candidate set to its weakest selected token. We argue that this leaves speed on the table because real decoding steps exhibit heterogeneous confidence profiles. We propose Fast-dLLM++, a training-free extension that introduces Fréchet profile decoding: selecting parallel commit sets from the full sorted confidence profile rather than a single worst-case confidence. The resulting rule is a heterogeneous-confidence generalization of Fast-dLLM's factor selector and it recovers the previous rule exactly in the equal-confidence case and adds a provable heterogeneity bonus when the selected tokens have uneven confidences. Fast-dLLM++ leaves the model, diffusion process, and cache implementation entirely unchanged, making it a drop-in replacement for existing Fast-dLLM decoding. Experiments on GSM8K, MATH, HumanEval, and MBPP with the LLaDA-8B model show that the theoretical improvement translates directly into empirical gains: profile-aware selection improves the accuracy--throughput frontier by exploiting safe parallelism that weakest-token rules miss, achieving up to 37\% higher throughput at comparable accuracy. Our code release is at https://github.com/Ringo-Star/FastdLLM_plusplus.

We introduce InVi, an approach for inserting or replacing objects within videos (referred to as inpainting) using off-the-shelf, text-to-image latent diffusion models. InVi targets controlled manipulation of objects and blending them seamlessly into a background video unlike existing video editing methods that focus on comprehensive re-styling or entire scene alterations. To achieve this goal, we tackle two key challenges. Firstly, for high quality control and blending, we employ a two-step process involving inpainting and matching. This process begins with inserting the object into a single frame using a ControlNet-based inpainting diffusion model, and then generating subsequent frames conditioned on features from an inpainted frame as an anchor to minimize the domain gap between the background and the object. Secondly, to ensure temporal coherence, we replace the diffusion model's self-attention layers with extended-attention layers. The anchor frame features serve as the keys and values for these layers, enhancing consistency across frames. Our approach removes the need for video-specific fine-tuning, presenting an efficient and adaptable solution. Experimental results demonstrate that InVi achieves realistic object insertion with consistent blending and coherence across frames, outperforming existing methods.

Instruction-based image editing enables natural-language control over visual modifications, yet existing models falter under Instruction-Visual Complexity (IV-Complexity), where intricate instructions meet cluttered or ambiguous scenes. We introduce RePlan (Region-aligned Planning), a plan-then-execute framework that couples a vision-language planner with a diffusion editor. The planner decomposes instructions via step-by-step reasoning and explicitly grounds them to target regions; the editor then applies changes using a training-free attention-region injection mechanism, enabling precise, parallel multi-region edits without iterative inpainting. To strengthen planning, we apply GRPO-based reinforcement learning using 1K instruction-only examples, yielding substantial gains in reasoning fidelity and format reliability. We further present IV-Edit, a benchmark focused on fine-grained grounding and knowledge-intensive edits. Across IV-Complex settings, RePlan consistently outperforms strong baselines trained on far larger datasets, improving regional precision and overall fidelity. Our project page: https://replan-iv-edit.github.io

Large Language Models (LLMs) are increasingly used for zero-shot annotation and LLM-as-a-judge tasks, yet their reliability hinges on how model-internalized priors interact with user-provided instructions. We investigate three dimensions of this interaction: (1) how an LLM's familiarity with data and task definitions affects performance, (2) the extent to which additional information in prompts can correct zero-shot errors ("decision stickiness"), and (3) model susceptibility to misaligned task definitions. Through experiments on toxicity detection across diverse datasets (spanning social media, gaming, news, and forums) using both dense and mixture-of-experts models, we find that nearly two-thirds of zero-shot errors are resistant to correction, with an overall rescue rate (fraction of initial errors corrected by prompting) of only 34.8%. High-confidence errors prove especially resistant to correction. When given misaligned definitions, LLMs follow them while maintaining confidence levels unchanged from the aligned condition. Crucially, we introduce Definition-Specific Familiarity (DSF), which measures alignment between a model's internal concept and the task definition. After controlling for dataset-level confounds, DSF shows a positive association with model performance (partial r = +0.41), while three distinct memorization metrics (ROUGE-L, BERTScore, and embedding cosine similarity) all fail to show a positive association. These findings show the limitations of prompt-based correction in annotation tasks, highlighting the importance of definition alignment over text-level memorization.

Text-guided image-to-video (TI2V) generation has recently achieved remarkable progress, particularly in maintaining subject consistency and temporal coherence. However, existing methods still struggle to adhere to fine-grained prompt semantics, especially when prompts entail substantial transformations of the input image (e.g., object addition, deletion, or modification), a shortcoming we term semantic negligence. In a pilot study, we find that applying a Gaussian blur to the input image improves semantic adherence. Analyzing attention maps, we observe clearer foreground-background separation. From an energy perspective, this corresponds to a lower-entropy cross-attention distribution. Motivated by this, we introduce AlignVid, a training-free framework with two components: (i) Attention Scaling Modulation (ASM), which directly reweights attention via lightweight Q or K scaling, and (ii) Guidance Scheduling (GS), which applies ASM selectively across transformer blocks and denoising steps to reduce visual quality degradation. This minimal intervention improves prompt adherence while limiting aesthetic degradation. In addition, we introduce OmitI2V to evaluate semantic negligence in TI2V generation, comprising 367 human-annotated samples that span addition, deletion, and modification scenarios. Extensive experiments demonstrate that AlignVid can enhance semantic fidelity.

This paper introduces a novel one-stage end-to-end detector specifically designed to detect small lesions in medical images. Precise localization of small lesions presents challenges due to their appearance and the diverse contextual backgrounds in which they are found. To address this, our approach introduces a new type of pixel-based anchor that dynamically moves towards the targeted lesion for detection. We refer to this new architecture as GravityNet, and the novel anchors as gravity points since they appear to be "attracted" by the lesions. We conducted experiments on two well-established medical problems involving small lesions to evaluate the performance of the proposed approach: microcalcifications detection in digital mammograms and microaneurysms detection in digital fundus images. Our method demonstrates promising results in effectively detecting small lesions in these medical imaging tasks.

The regression of 3D Human Pose and Shape (HPS) from an image is becoming increasingly accurate. This makes the results useful for downstream tasks like human action recognition or 3D graphics. Yet, no regressor is perfect, and accuracy can be affected by ambiguous image evidence or by poses and appearance that are unseen during training. Most current HPS regressors, however, do not report the confidence of their outputs, meaning that downstream tasks cannot differentiate accurate estimates from inaccurate ones. To address this, we develop POCO, a novel framework for training HPS regressors to estimate not only a 3D human body, but also their confidence, in a single feed-forward pass. Specifically, POCO estimates both the 3D body pose and a per-sample variance. The key idea is to introduce a Dual Conditioning Strategy (DCS) for regressing uncertainty that is highly correlated to pose reconstruction quality. The POCO framework can be applied to any HPS regressor and here we evaluate it by modifying HMR, PARE, and CLIFF. In all cases, training the network to reason about uncertainty helps it learn to more accurately estimate 3D pose. While this was not our goal, the improvement is modest but consistent. Our main motivation is to provide uncertainty estimates for downstream tasks; we demonstrate this in two ways: (1) We use the confidence estimates to bootstrap HPS training. Given unlabelled image data, we take the confident estimates of a POCO-trained regressor as pseudo ground truth. Retraining with this automatically-curated data improves accuracy. (2) We exploit uncertainty in video pose estimation by automatically identifying uncertain frames (e.g. due to occlusion) and inpainting these from confident frames. Code and models will be available for research at https://poco.is.tue.mpg.de.

Intra-fraction motion in radiotherapy is commonly modeled using deformable image registration (DIR). However, existing methods often struggle to balance speed and accuracy, limiting their applicability in clinical scenarios. This study introduces a novel approach that harnesses Neural Graphics Primitives (NGP) to optimize the displacement vector field (DVF). Our method leverages learned primitives, processed as splats, and interpolates within space using a shallow neural network. Uniquely, it enables self-supervised optimization at an ultra-fast speed, negating the need for pre-training on extensive datasets and allowing seamless adaptation to new cases. We validated this approach on the 4D-CT lung dataset DIR-lab, achieving a target registration error (TRE) of 1.15\pm1.15 mm within a remarkable time of 1.77 seconds. Notably, our method also addresses the sliding boundary problem, a common challenge in conventional DIR methods.

Intraoperative bleeding during Endoscopic Submucosal Dissection (ESD) poses significant risks, demanding precise, real-time localization and continuous monitoring of the bleeding source for effective hemostatic intervention. In particular, endoscopists have to repeatedly flush to clear blood, allowing only milliseconds to identify bleeding sources, an inefficient process that prolongs operations and elevates patient risks. However, current Artificial Intelligence (AI) methods primarily focus on bleeding region segmentation, overlooking the critical need for accurate bleeding source detection and temporal tracking in the challenging ESD environment, which is marked by frequent visual obstructions and dynamic scene changes. This gap is widened by the lack of specialized datasets, hindering the development of robust AI-assisted guidance systems. To address these challenges, we introduce BleedOrigin-Bench, the first comprehensive ESD bleeding source dataset, featuring 1,771 expert-annotated bleeding sources across 106,222 frames from 44 procedures, supplemented with 39,755 pseudo-labeled frames. This benchmark covers 8 anatomical sites and 6 challenging clinical scenarios. We also present BleedOrigin-Net, a novel dual-stage detection-tracking framework for the bleeding source localization in ESD procedures, addressing the complete workflow from bleeding onset detection to continuous spatial tracking. We compare with widely-used object detection models (YOLOv11/v12), multimodal large language models, and point tracking methods. Extensive evaluation demonstrates state-of-the-art performance, achieving 96.85% frame-level accuracy (pmleq8 frames) for bleeding onset detection, 70.24% pixel-level accuracy (leq100 px) for initial source detection, and 96.11% pixel-level accuracy (leq100 px) for point tracking.

Parameter-efficient adaptation of vision-language foundation models is crucial for precise multimodal understanding of biomedical images, yet existing methods remain deterministic and often struggle under domain shift or ambiguous image-text alignment. This limitation is particularly critical in the clinic, where models should remain robust in low-data regimes and domain shifts. We present Evi-Steer, an evidential cross-modal low-dimensional steering framework for BiomedCLIP that enables uncertainty-aware parameter-efficient fine-tuning while updating only 0.11% of total model parameters. Our approach performs lightweight low-dimensional token updates in both vision and text encoders while simultaneously estimating epistemic uncertainty. These uncertainty estimates update gate residuals, allowing the model to adapt conservatively when evidence is weak. Furthermore, we introduce cross-modal confidence fusion based on Dempster-Shafer theory, enabling visual adaptation to be conditioned on textual confidence and suppressing conflicting or uncertain cross-modal updates. We conduct a comprehensive evaluation on 15 biomedical imaging datasets spanning 8 organs and 8 imaging modalities under few-shot learning and domain generalization settings. Evi-Steer consistently outperforms state-of-the-art methods under few-shot learning and domain shift settings, demonstrating a practical and robust pathway for deploying vision-language models in real-world clinical settings. Code is available at https://github.com/HealthX-Lab/Evi-Steer.

During the radiotherapy treatment of patients with lung cancer, the radiation delivered to healthy tissue around the tumor needs to be minimized, which is difficult because of respiratory motion and the latency of linear accelerator systems. In the proposed study, we first use the Lucas-Kanade pyramidal optical flow algorithm to perform deformable image registration of chest computed tomography scan images of four patients with lung cancer. We then track three internal points close to the lung tumor based on the previously computed deformation field and predict their position with a recurrent neural network (RNN) trained using real-time recurrent learning (RTRL) and gradient clipping. The breathing data is quite regular, sampled at approximately 2.5Hz, and includes artificial drift in the spine direction. The amplitude of the motion of the tracked points ranged from 12.0mm to 22.7mm. Finally, we propose a simple method for recovering and predicting 3D tumor images from the tracked points and the initial tumor image based on a linear correspondence model and Nadaraya-Watson non-linear regression. The root-mean-square error, maximum error, and jitter corresponding to the RNN prediction on the test set were smaller than the same performance measures obtained with linear prediction and least mean squares (LMS). In particular, the maximum prediction error associated with the RNN, equal to 1.51mm, is respectively 16.1% and 5.0% lower than the maximum error associated with linear prediction and LMS. The average prediction time per time step with RTRL is equal to 119ms, which is less than the 400ms marker position sampling time. The tumor position in the predicted images appears visually correct, which is confirmed by the high mean cross-correlation between the original and predicted images, equal to 0.955.

Selecting the best response from multiple small-model samples using a stronger scorer is a simple inference-time strategy, but fails when the small model has already committed to incorrect reasoning paths. PRM guided search avoids this by scoring candidate continuations during generation, but requires a reward model trained with step-level labels. We propose Chunk-Level Guided Generation, a training-free alternative that uses an off-the-shelf large language model as a process scorer. At each step, a small model samples k fixed-length candidate chunks, while the larger model scores the candidates using likelihoods without generating any text. The selected chunk is committed before the next step, steering generation before errors can propagate. We instantiate this framework with two selection rules: Likelihood-Guided Selection (LGS), which selects the chunk with the highest length-normalized large-model log-probability, and Contrastive-Guided Selection (CGS), which subtracts the small model's log-probability to favor chunks where the large model's preference diverges from the small model's. We show that scoring variable-length reasoning steps with large-model likelihoods is unreliable due to a systematic length bias that persists even after length normalization, and that fixed-length chunks avoid this confound. On GSM8K, MATH, Minerva Math, AMC23, and AIME24 with Qwen2.5-1.5B guided by Qwen2.5-32B and Llama-3.2-1B guided by Llama-3.1-70B, CGS outperforms majority voting by up to 28 pp and, under matched guidance budgets, matches or outperforms Qwen2.5-Math-PRM-72B guided search on most benchmarks without reward-model training. With Qwen2.5-7B guided by Qwen2.5-72B, CGS reaches 81.8% on MATH and 63.6% on Minerva Math at k=16, surpassing majority voting by 4--6 pp. Finally, Chunk-Level Guided Generation produces substantially shorter reasoning traces than PRM guided search.

Automatic diabetic retinopathy (DR) lesions segmentation makes great sense of assisting ophthalmologists in diagnosis. Although many researches have been conducted on this task, most prior works paid too much attention to the designs of networks instead of considering the pathological association for lesions. Through investigating the pathogenic causes of DR lesions in advance, we found that certain lesions are closed to specific vessels and present relative patterns to each other. Motivated by the observation, we propose a relation transformer block (RTB) to incorporate attention mechanisms at two main levels: a self-attention transformer exploits global dependencies among lesion features, while a cross-attention transformer allows interactions between lesion and vessel features by integrating valuable vascular information to alleviate ambiguity in lesion detection caused by complex fundus structures. In addition, to capture the small lesion patterns first, we propose a global transformer block (GTB) which preserves detailed information in deep network. By integrating the above blocks of dual-branches, our network segments the four kinds of lesions simultaneously. Comprehensive experiments on IDRiD and DDR datasets well demonstrate the superiority of our approach, which achieves competitive performance compared to state-of-the-arts.

Self-consistency decoding enhances LLMs' performance on reasoning tasks by sampling diverse reasoning paths and selecting the most frequent answer. However, it is computationally expensive, as sampling many of these (lengthy) paths is required to increase the chances that the correct answer emerges as the most frequent one. To address this, we introduce Confidence-Informed Self-Consistency (CISC). CISC performs a weighted majority vote based on confidence scores obtained directly from the model. By prioritizing high-confidence paths, it can identify the correct answer with a significantly smaller sample size. When tested on nine models and four datasets, CISC outperforms self-consistency in nearly all configurations, reducing the required number of reasoning paths by over 40% on average. In addition, we introduce the notion of within-question confidence evaluation, after showing that standard evaluation methods are poor predictors of success in distinguishing correct and incorrect answers to the same question. In fact, the most calibrated confidence method proved to be the least effective for CISC. Lastly, beyond these practical implications, our results and analyses show that LLMs can effectively judge the correctness of their own outputs, contributing to the ongoing debate on this topic.

Large language models (LLMs) tend to verbalize confidence scores that are largely detached from their actual accuracy, yet the geometric relationship governing this behavior remain poorly understood. In this work, we present a mechanistic interpretability analysis of verbalized confidence, using linear probes and contrastive activation addition (CAA) steering to show that calibration and verbalized confidence signals are encoded linearly but are orthogonal to one another -- a finding consistent across three open-weight models and four datasets. Interestingly, when models are prompted to simultaneously reason through a problem and verbalize a confidence score, the reasoning process disrupts the verbalized confidence direction, exacerbating miscalibration. We term this the "Reasoning Contamination Effect." Leveraging this insight, we introduce a two-stage adaptive steering pipeline that reads the model's internal accuracy estimate and steers verbalized output to match it, substantially improving calibration alignment across all evaluated models.

Recent machine learning papers often report 1-2 percentage point improvements from a single run on a benchmark. These gains are highly sensitive to random seeds, data ordering, and implementation details, yet are rarely accompanied by uncertainty estimates or significance tests. It is therefore unclear when a reported +1-2% reflects a real algorithmic advance versus noise. We revisit this problem under realistic compute budgets, where only a few runs are affordable. We propose a simple, PC-friendly evaluation protocol based on paired multi-seed runs, bias-corrected and accelerated (BCa) bootstrap confidence intervals, and a sign-flip permutation test on per-seed deltas. The protocol is intentionally conservative and is meant as a guardrail against over-claiming. We instantiate it on CIFAR-10, CIFAR-10N, and AG News using synthetic no-improvement, small-gain, and medium-gain scenarios. Single runs and unpaired t-tests often suggest significant gains for 0.6-2.0 point improvements, especially on text. With only three seeds, our paired protocol never declares significance in these settings. We argue that such conservative evaluation is a safer default for small gains under tight budgets.

Diffusion models have shown remarkable performance in image generation in recent years. However, due to a quadratic increase in memory during generating ultra-high-resolution images (e.g. 4096*4096), the resolution of generated images is often limited to 1024*1024. In this work. we propose a unidirectional block attention mechanism that can adaptively adjust the memory overhead during the inference process and handle global dependencies. Building on this module, we adopt the DiT structure for upsampling and develop an infinite super-resolution model capable of upsampling images of various shapes and resolutions. Comprehensive experiments show that our model achieves SOTA performance in generating ultra-high-resolution images in both machine and human evaluation. Compared to commonly used UNet structures, our model can save more than 5x memory when generating 4096*4096 images. The project URL is https://github.com/THUDM/Inf-DiT.

Flow-based generative models have achieved remarkable progress, with classifier-free guidance (CFG) becoming the standard for high-fidelity generation. However, the conventional practice of applying a strong, fixed guidance scale throughout inference is poorly suited for the rapid, few-step sampling required by modern applications. In this work, we uncover the root cause of this conflict: a fundamental sampling instability where the earliest steps are acutely sensitive to guidance. We trace this to a significant spike in the ratio of conditional to unconditional predictions--a spike that we prove to be an inherent property of the training data distribution itself, making it a almost inevitable challenge. Applying a high, static guidance value during this volatile initial phase leads to an exponential amplification of error, degrading image quality. To resolve this, we propose a simple, theoretically grounded, adaptive guidance schedule that automatically dampens the guidance scale at early steps based on the evolving ratio. Our method is lightweight, incurs no inference overhead, and is compatible with standard frameworks. Experiments across state-of-the-art image (SD3.5, Qwen-Image) and video (WAN2.1) models show our approach enables up to 3x faster sampling while maintaining or improving quality, robustness, and semantic alignment. Our findings highlight that adapting guidance to the sampling process, rather than fixing it, is critical for unlocking the full potential of fast, flow-based models.

The scarcity of high-quality data remains a primary bottleneck in adapting multimodal generative models for medical image editing. Existing medical image editing datasets often suffer from limited diversity, neglect of medical image understanding and inability to balance quality with scalability. To address these gaps, we propose MieDB-100k, a large-scale, high-quality and diverse dataset for text-guided medical image editing. It categorizes editing tasks into perspectives of Perception, Modification and Transformation, considering both understanding and generation abilities. We construct MieDB-100k via a data curation pipeline leveraging both modality-specific expert models and rule-based data synthetic methods, followed by rigorous manual inspection to ensure clinical fidelity. Extensive experiments demonstrate that model trained with MieDB-100k consistently outperform both open-source and proprietary models while exhibiting strong generalization ability. We anticipate that this dataset will serve as a cornerstone for future advancements in specialized medical image editing.

Diffusion models are widely used for generative tasks across domains. Given a pre-trained diffusion model, it is often desirable to fine-tune it further either to correct for errors in learning or to align with downstream applications. Towards this, we examine the effect of shaping the distribution at intermediate noise levels induced by diffusion models. First, we show that existing variants of Rejection sAmpling based Fine-Tuning (RAFT), which we unify as GRAFT, can implicitly perform KL regularized reward maximization with reshaped rewards. Motivated by this observation, we introduce P-GRAFT to shape distributions at intermediate noise levels and demonstrate empirically that this can lead to more effective fine-tuning. We mathematically explain this via a bias-variance tradeoff. Next, we look at correcting learning errors in pre-trained flow models based on the developed mathematical framework. In particular, we propose inverse noise correction, a novel algorithm to improve the quality of pre-trained flow models without explicit rewards. We empirically evaluate our methods on text-to-image(T2I) generation, layout generation, molecule generation and unconditional image generation. Notably, our framework, applied to Stable Diffusion v2, improves over policy gradient methods on popular T2I benchmarks in terms of VQAScore and shows an 8.81% relative improvement over the base model. For unconditional image generation, inverse noise correction improves FID of generated images at lower FLOPs/image.

Activation steering has emerged as a cost-effective paradigm for modifying large language model (LLM) behaviors. Existing methods typically intervene at the block level, steering the bundled activations of selected attention heads, feedforward networks, or residual streams. However, we reveal that block-level activations are inherently heterogeneous, entangling beneficial, irrelevant, and harmful features, thereby rendering block-level steering coarse, inefficient, and intrusive. To investigate the root cause, we decompose block activations into fine-grained atomic unit (AU)-level activations, where each AU-level activation corresponds to a single dimension of the block activation, and each AU denotes a slice of the block weight matrix. Steering an AU-level activation is thus equivalent to steering its associated AU. Our theoretical and empirical analysis show that heterogeneity arises because different AUs or dimensions control distinct token distributions in LLM outputs. Hence, block-level steering inevitably moves helpful and harmful token directions together, which reduces efficiency. Restricting intervention to beneficial AUs yields more precise and effective steering. Building on this insight, we propose AUSteer, a simple and efficient method that operates at a finer granularity of the AU level. AUSteer first identifies discriminative AUs globally by computing activation momenta on contrastive samples. It then assigns adaptive steering strengths tailored to diverse inputs and selected AU activations. Comprehensive experiments on multiple LLMs and tasks show that AUSteer consistently surpasses advanced baselines while steering considerably fewer activations, demonstrating that steering less achieves more.

Instruction-based video editing allows effective and interactive editing of videos using only instructions without extra inputs such as masks or attributes. However, collecting high-quality training triplets (source video, edited video, instruction) is a challenging task. Existing datasets mostly consist of low-resolution, short duration, and limited amount of source videos with unsatisfactory editing quality, limiting the performance of trained editing models. In this work, we present a high-quality Instruction-based Video Editing dataset with 1M triplets, namely InsViE-1M. We first curate high-resolution and high-quality source videos and images, then design an effective editing-filtering pipeline to construct high-quality editing triplets for model training. For a source video, we generate multiple edited samples of its first frame with different intensities of classifier-free guidance, which are automatically filtered by GPT-4o with carefully crafted guidelines. The edited first frame is propagated to subsequent frames to produce the edited video, followed by another round of filtering for frame quality and motion evaluation. We also generate and filter a variety of video editing triplets from high-quality images. With the InsViE-1M dataset, we propose a multi-stage learning strategy to train our InsViE model, progressively enhancing its instruction following and editing ability. Extensive experiments demonstrate the advantages of our InsViE-1M dataset and the trained model over state-of-the-art works. Codes are available at InsViE.

Instruction-based image editing through natural language has emerged as a powerful paradigm for intuitive visual manipulation. While recent models achieve impressive results on single edits, they suffer from severe quality degradation under multi-turn editing. Through systematic analysis, we identify progressive loss of high-frequency information as the primary cause of this quality degradation. We present FreqEdit, a training-free framework that enables stable editing across 10+ consecutive iterations. Our approach comprises three synergistic components: (1) high-frequency feature injection from reference velocity fields to preserve fine-grained details, (2) an adaptive injection strategy that spatially modulates injection strength for precise region-specific control, and (3) a path compensation mechanism that periodically recalibrates the editing trajectory to prevent over-constraint. Extensive experiments demonstrate that FreqEdit achieves superior performance in both identity preservation and instruction following compared to seven state-of-the-art baselines.

Frozen encoders are chosen by how well a lightweight head reads a finding from their features, not whether the geometry separates it. Nearest-neighbor discordance does, but with unequal banks the opposite-label neighbor wins on density, not geometry, so prevalence alone makes an uninformed encoder look blind. We introduce CANDOR, a discordance measure whose equal-size banks are symmetric under a label swap, fixing its chance level at exactly one half. Across 22 encoders, 20 datasets from 7 domains, and 605,443 images, this correction reverses the conclusion. Collapse falls below chance almost everywhere, so no encoder is blind, yet all are weak: the best chest model reads pneumothorax at 84.5 AUROC and still places 18.4% of those positives nearer an opposite-label film than its own kind in the same hospital. The same encoder that resolves bird species at 4.5 leaves chest findings at 42.8 and glaucoma at 49.8, at chance and worse than random weights. Such a case caps the normalized margin of any Lipschitz head, yet some head among eleven is correct on all but 2.8% of cases where one head misses 35.9%: the deficit is selection, not information. Erasure retention is associated with collapse; we detect no association with the objective, scale, recency, or size of the finding. Because the chance level is fixed, CANDOR can be read before any head is trained, flagging which findings a frozen encoder supports poorly.

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports anatomically-controllable medical image generation, by following a multi-class anatomical segmentation mask at each sampling step. We additionally introduce a random mask ablation training algorithm to enable conditioning on a selected combination of anatomical constraints while allowing flexibility in other anatomical areas. We compare our method ("SegGuidedDiff") to existing methods on breast MRI and abdominal/neck-to-pelvis CT datasets with a wide range of anatomical objects. Results show that our method reaches a new state-of-the-art in the faithfulness of generated images to input anatomical masks on both datasets, and is on par for general anatomical realism. Finally, our model also enjoys the extra benefit of being able to adjust the anatomical similarity of generated images to real images of choice through interpolation in its latent space. SegGuidedDiff has many applications, including cross-modality translation, and the generation of paired or counterfactual data. Our code is available at https://github.com/mazurowski-lab/segmentation-guided-diffusion.

Recent advances in image editing have been driven by the development of denoising diffusion models, marking a significant leap forward in this field. Despite these advances, the generalization capabilities of recent image editing approaches remain constrained. In response to this challenge, our study introduces a novel image editing framework with enhanced generalization robustness by boosting in-context learning capability and unifying language instruction. This framework incorporates a module specifically optimized for image editing tasks, leveraging the VMamba Block and an editing-shift matching strategy to augment in-context learning. Furthermore, we unveil a selective area-matching technique specifically engineered to address and rectify corrupted details in generated images, such as human facial features, to further improve the quality. Another key innovation of our approach is the integration of a language unification technique, which aligns language embeddings with editing semantics to elevate the quality of image editing. Moreover, we compile the first dataset for image editing with visual prompts and editing instructions that could be used to enhance in-context capability. Trained on this dataset, our methodology not only achieves superior synthesis quality for trained tasks, but also demonstrates robust generalization capability across unseen vision tasks through tailored prompts.

Neural Radiance Fields (NeRF) exhibit remarkable performance for Novel View Synthesis (NVS) given a set of 2D images. However, NeRF training requires accurate camera pose for each input view, typically obtained by Structure-from-Motion (SfM) pipelines. Recent works have attempted to relax this constraint, but they still often rely on decent initial poses which they can refine. Here we aim at removing the requirement for pose initialization. We present Incremental CONfidence (ICON), an optimization procedure for training NeRFs from 2D video frames. ICON only assumes smooth camera motion to estimate initial guess for poses. Further, ICON introduces ``confidence": an adaptive measure of model quality used to dynamically reweight gradients. ICON relies on high-confidence poses to learn NeRF, and high-confidence 3D structure (as encoded by NeRF) to learn poses. We show that ICON, without prior pose initialization, achieves superior performance in both CO3D and HO3D versus methods which use SfM pose.

Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of the results, but is tedious, time consuming and prone to operator bias. Fully automated methods require no human effort, but often deliver sub-optimal results without providing users with the means to make corrections. Semi-automated approaches keep users in control of the results by providing means for interaction, but the main challenge is to offer a good trade-off between precision and required interaction. In this paper we present a deep learning (DL) based semi-automated segmentation approach that aims to be a "smart" interactive tool for region of interest delineation in medical images. We demonstrate its use for segmenting multiple organs on computed tomography (CT) of the abdomen. Our approach solves some of the most pressing clinical challenges: (i) it requires only one to a few user clicks to deliver excellent 2D segmentations in a fast and reliable fashion; (ii) it can generalize to previously unseen structures and "corner cases"; (iii) it delivers results that can be corrected quickly in a smart and intuitive way up to an arbitrary degree of precision chosen by the user and (iv) ensures high accuracy. We present our approach and compare it to other techniques and previous work to show the advantages brought by our method.

One of the most compelling features of global discrete diffusion language models is their global bidirectional contextual capability. However, existing block-based diffusion studies tend to introduce autoregressive priors, which, while offering benefits, can cause models to lose this global coherence at the macro level. To regain global contextual understanding while preserving the advantages of the semi-autoregressive paradigm, we propose Diffusion in Diffusion, a 'draft-then-refine' framework designed to overcome the irreversibility and myopia problems inherent in block diffusion models. Our approach first employs block diffusion to generate rapid drafts using small blocks, then refines these drafts through global bidirectional diffusion with a larger bidirectional receptive field. We utilize snapshot confidence remasking to identify the most critical tokens that require modification, and apply mix-scale training to expand the block diffusion model's global capabilities. Empirical results demonstrate that our approach sets a new benchmark for discrete diffusion models on the OpenWebText dataset. Using only 26% of the fine-tuning budget of baseline models, we reduce generative perplexity from 25.7 to 21.9, significantly narrowing the performance gap with autoregressive models.

Recent advances in training-free attention control methods have enabled flexible and efficient text-guided editing capabilities for existing generation models. However, current approaches struggle to simultaneously deliver strong editing strength while preserving consistency with the source. This limitation becomes particularly critical in multi-round and video editing, where visual errors can accumulate over time. Moreover, most existing methods enforce global consistency, which limits their ability to modify individual attributes such as texture while preserving others, thereby hindering fine-grained editing. Recently, the architectural shift from U-Net to MM-DiT has brought significant improvements in generative performance and introduced a novel mechanism for integrating text and vision modalities. These advancements pave the way for overcoming challenges that previous methods failed to resolve. Through an in-depth analysis of MM-DiT, we identify three key insights into its attention mechanisms. Building on these, we propose ConsistEdit, a novel attention control method specifically tailored for MM-DiT. ConsistEdit incorporates vision-only attention control, mask-guided pre-attention fusion, and differentiated manipulation of the query, key, and value tokens to produce consistent, prompt-aligned edits. Extensive experiments demonstrate that ConsistEdit achieves state-of-the-art performance across a wide range of image and video editing tasks, including both structure-consistent and structure-inconsistent scenarios. Unlike prior methods, it is the first approach to perform editing across all inference steps and attention layers without handcraft, significantly enhancing reliability and consistency, which enables robust multi-round and multi-region editing. Furthermore, it supports progressive adjustment of structural consistency, enabling finer control.

Long chains of thought (CoT) from current language models frequently contain logical gaps and unjustified leaps, limiting the gains from additional test-time compute. Improving reasoning quality directly would require process reward models, but the step-level annotations needed to train them are expensive and scarce. We find such a signal in how the model's confidence evolves during reasoning: premature confidence, the tendency to commit to an answer early and use the remaining tokens to rationalize it, strongly predicts flawed reasoning across tasks and model scales. We exploit this in progressive confidence shaping, a reinforcement learning objective that trains models to update their confidence as they reason rather than commit early -- rewarding gradual confidence growth and penalizing early commitment, with no external labels or reward models. The method improves accuracy and reasoning quality from 1.5B to 8B parameters across arithmetic (Countdown), math (DAPO, AIME), and science (ScienceQA): on Countdown, accuracy improves 3.2x (+42.0pp) and flawed reasoning drops 48pp; on AIME, Pass@64 improves 6.6pp. Consistent with this mechanism, the method also improves faithfulness: on a safety benchmark, our models more transparently surface misleading content in their reasoning traces rather than concealing it. Controlled experiments reveal that the problem and its remedy scale together: premature confidence grows with model size and task difficulty, and so do the gains from addressing it.

Text-guided image and 3D editing have advanced with diffusion-based models, yet methods like Delta Denoising Score often struggle with stability, spatial control, and editing strength. These limitations stem from reliance on complex auxiliary structures, which introduce conflicting optimization signals and restrict precise, localized edits. We introduce Stable Score Distillation (SSD), a streamlined framework that enhances stability and alignment in the editing process by anchoring a single classifier to the source prompt. Specifically, SSD utilizes Classifier-Free Guidance (CFG) equation to achieves cross-prompt alignment, and introduces a constant term null-text branch to stabilize the optimization process. This approach preserves the original content's structure and ensures that editing trajectories are closely aligned with the source prompt, enabling smooth, prompt-specific modifications while maintaining coherence in surrounding regions. Additionally, SSD incorporates a prompt enhancement branch to boost editing strength, particularly for style transformations. Our method achieves state-of-the-art results in 2D and 3D editing tasks, including NeRF and text-driven style edits, with faster convergence and reduced complexity, providing a robust and efficient solution for text-guided editing.

Is the uniform-state diffusion framework a more powerful paradigm for discrete diffusion? Recent studies indicate that this may be the case. In combination with predictor-corrector samplers, uniform-state diffusion models (USDMs) produce samples of higher-quality than masked diffusion models (MDMs), and USDMs equal or outperform MDMs in downstream tasks, even though they exhibit greater perplexity. Two issues remain unresolved. First, existing work compares uniform and masked diffusion with un-informed correctors that re-inject noise at random positions, rather than targeting tokens most likely to be wrong. Second, prior work compares full-sequence diffusion models, so we do not know whether the same conclusion holds when tokens are generated block by block. To address these issues, we introduce BlockGen, a blockwise sequence model that we instantiate with both masked and uniform diffusion. BlockGen trains on a mixture of block sizes and its likelihood interpolates between AR and pure diffusion more finely than models with a fixed block size. BlockGen enables AR-informed predictor-corrector sampling (ARPC), which combines AR and diffusion predictions to re-generate unlikely tokens without an auxiliary verifier. Under ancestral sampling, uniform outperforms masked in the block-by-block setting, especially in the few-step regime. Under ARPC, the gap closes and reverses at high NFE. With block size 16 on GSM8K, MDMs reach slightly higher accuracy than USDMs, and we observe a similar trend in Generative Perplexity on OpenWebText. Find our code at https://github.com/jdeschena/blockgen.