Daily Papers

Sound sources localization using multichannel signal processing has been a subject of active research for decades. In recent years, the use of deep learning in audio signal processing has allowed to drastically improve performances for machine hearing. This has motivated the scientific community to also develop machine learning strategies for source localization applications. In this paper, we present BeamLearning, a multi-resolution deep learning approach that allows to encode relevant information contained in unprocessed time domain acoustic signals captured by microphone arrays. The use of raw data aims at avoiding simplifying hypothesis that most traditional model-based localization methods rely on. Benefits of its use are shown for realtime sound source 2D-localization tasks in reverberating and noisy environments. Since supervised machine learning approaches require large-sized, physically realistic, precisely labelled datasets, we also developed a fast GPU-based computation of room impulse responses using fractional delays for image source models. A thorough analysis of the network representation and extensive performance tests are carried out using the BeamLearning network with synthetic and experimental datasets. Obtained results demonstrate that the BeamLearning approach significantly outperforms the wideband MUSIC and SRP-PHAT methods in terms of localization accuracy and computational efficiency in presence of heavy measurement noise and reverberation.

This paper presents a novel end-to-end deep learning framework for real-time inertial attitude estimation using 6DoF IMU measurements. Inertial Measurement Units are widely used in various applications, including engineering and medical sciences. However, traditional filters used for attitude estimation suffer from poor generalization over different motion patterns and environmental disturbances. To address this problem, we propose two deep learning models that incorporate accelerometer and gyroscope readings as inputs. These models are designed to be generalized to different motion patterns, sampling rates, and environmental disturbances. Our models consist of convolutional neural network layers combined with Bi-Directional Long-Short Term Memory followed by a Fully Forward Neural Network to estimate the quaternion. We evaluate the proposed method on seven publicly available datasets, totaling more than 120 hours and 200 kilometers of IMU measurements. Our results show that the proposed method outperforms state-of-the-art methods in terms of accuracy and robustness. Additionally, our framework demonstrates superior generalization over various motion characteristics and sensor sampling rates. Overall, this paper provides a comprehensive and reliable solution for real-time inertial attitude estimation using 6DoF IMUs, which has significant implications for a wide range of applications.

3D models are widely used in various industries, and mesh data has become an indispensable part of 3D modeling because of its unique advantages. Mesh data can provide an intuitive and practical expression of rich 3D information. However, its disordered, irregular data structure and complex surface information make it challenging to apply with deep learning models directly. Traditional mesh data processing methods often rely on mesh models with many limitations, such as manifold, which restrict their application scopes in reality and do not fully utilize the advantages of mesh models. This paper proposes a novel end-to-end framework for addressing the challenges associated with deep learning in mesh models centered around graph neural networks (GNN) and is titled InfoGNN. InfoGNN treats the mesh model as a graph, which enables it to handle irregular mesh data efficiently. Moreover, we propose InfoConv and InfoMP modules, which utilize the position information of the points and fully use the static information such as face normals, dihedral angles, and dynamic global feature information to fully use all kinds of data. In addition, InfoGNN is an end-to-end framework, and we simplify the network design to make it more efficient, paving the way for efficient deep learning of complex 3D models. We conducted experiments on several publicly available datasets, and the results show that InfoGNN achieves excellent performance in mesh classification and segmentation tasks.

The Quran is the holy scripture of Islam, and its recitation is an important aspect of the religion. Recognizing the recitation of the Holy Quran automatically is a challenging task due to its unique rules that are not applied in normal speaking speeches. A lot of research has been done in this domain, but previous works have detected recitation errors as a classification task or used traditional automatic speech recognition (ASR). In this paper, we proposed a novel end-to-end deep learning model for recognizing the recitation of the Holy Quran. The proposed model is a CNN-Bidirectional GRU encoder that uses CTC as an objective function, and a character-based decoder which is a beam search decoder. Moreover, all previous works were done on small private datasets consisting of short verses and a few chapters of the Holy Quran. As a result of using private datasets, no comparisons were done. To overcome this issue, we used a public dataset that has recently been published (Ar-DAD) and contains about 37 chapters that were recited by 30 reciters, with different recitation speeds and different types of pronunciation rules. The proposed model performance was evaluated using the most common evaluation metrics in speech recognition, word error rate (WER), and character error rate (CER). The results were 8.34% WER and 2.42% CER. We hope this research will be a baseline for comparisons with future research on this public new dataset (Ar-DAD).

Objective: Heart murmurs are abnormal sounds caused by turbulent blood flow within the heart. Several diagnostic methods are available to detect heart murmurs and their severity, such as cardiac auscultation, echocardiography, phonocardiogram (PCG), etc. However, these methods have limitations, including extensive training and experience among healthcare providers, cost and accessibility of echocardiography, as well as noise interference and PCG data processing. This study aims to develop a novel end-to-end real-time heart murmur detection approach using traditional and depthwise separable convolutional networks. Methods: Continuous wavelet transform (CWT) was applied to extract meaningful features from the PCG data. The proposed network has three parts: the Squeeze net, the Bottleneck, and the Expansion net. The Squeeze net generates a compressed data representation, whereas the Bottleneck layer reduces computational complexity using a depthwise-separable convolutional network. The Expansion net is responsible for up-sampling the compressed data to a higher dimension, capturing tiny details of the representative data. Results: For evaluation, we used four publicly available datasets and achieved state-of-the-art performance in all datasets. Furthermore, we tested our proposed network on two resource-constrained devices: a Raspberry PI and an Android device, stripping it down into a tiny machine learning model (TinyML), achieving a maximum of 99.70%. Conclusion: The proposed model offers a deep learning framework for real-time accurate heart murmur detection within limited resources. Significance: It will significantly result in more accessible and practical medical services and reduced diagnosis time to assist medical professionals. The code is publicly available at TBA.

With the widespread use of mobile phones and scanners to photograph and upload documents, the need for extracting the information trapped in unstructured document images such as retail receipts, insurance claim forms and financial invoices is becoming more acute. A major hurdle to this objective is that these images often contain information in the form of tables and extracting data from tabular sub-images presents a unique set of challenges. This includes accurate detection of the tabular region within an image, and subsequently detecting and extracting information from the rows and columns of the detected table. While some progress has been made in table detection, extracting the table contents is still a challenge since this involves more fine grained table structure(rows & columns) recognition. Prior approaches have attempted to solve the table detection and structure recognition problems independently using two separate models. In this paper, we propose TableNet: a novel end-to-end deep learning model for both table detection and structure recognition. The model exploits the interdependence between the twin tasks of table detection and table structure recognition to segment out the table and column regions. This is followed by semantic rule-based row extraction from the identified tabular sub-regions. The proposed model and extraction approach was evaluated on the publicly available ICDAR 2013 and Marmot Table datasets obtaining state of the art results. Additionally, we demonstrate that feeding additional semantic features further improves model performance and that the model exhibits transfer learning across datasets. Another contribution of this paper is to provide additional table structure annotations for the Marmot data, which currently only has annotations for table detection.

Current approaches to chemical map generation from hyperspectral images are based on models such as partial least squares (PLS) regression, generating pixel-wise predictions that do not consider spatial context and suffer from a high degree of noise. This study proposes an end-to-end deep learning approach using a modified version of U-Net and a custom loss function to directly obtain chemical maps from hyperspectral images, skipping all intermediate steps required for traditional pixel-wise analysis. We compare the U-Net with the traditional PLS regression on a real dataset of pork belly samples with associated mean fat reference values. The U-Net obtains a test set root mean squared error of between 9% and 13% lower than that of PLS regression on the task of mean fat prediction. At the same time, U-Net generates fine detail chemical maps where 99.91% of the variance is spatially correlated. Conversely, only 2.53% of the variance in the PLS-generated chemical maps is spatially correlated, indicating that each pixel-wise prediction is largely independent of neighboring pixels. Additionally, while the PLS-generated chemical maps contain predictions far beyond the physically possible range of 0-100%, U-Net learns to stay inside this range. Thus, the findings of this study indicate that U-Net is superior to PLS for chemical map generation.

We show that an end-to-end deep learning approach can be used to recognize either English or Mandarin Chinese speech--two vastly different languages. Because it replaces entire pipelines of hand-engineered components with neural networks, end-to-end learning allows us to handle a diverse variety of speech including noisy environments, accents and different languages. Key to our approach is our application of HPC techniques, resulting in a 7x speedup over our previous system. Because of this efficiency, experiments that previously took weeks now run in days. This enables us to iterate more quickly to identify superior architectures and algorithms. As a result, in several cases, our system is competitive with the transcription of human workers when benchmarked on standard datasets. Finally, using a technique called Batch Dispatch with GPUs in the data center, we show that our system can be inexpensively deployed in an online setting, delivering low latency when serving users at scale.

Diagnosis and risk stratification of cancer and many other diseases require the detection of genomic breakpoints as a prerequisite of calling copy number alterations (CNA). This, however, is still challenging and requires time-consuming manual curation. As deep-learning methods outperformed classical state-of-the-art algorithms in various domains and have also been successfully applied to life science problems including medicine and biology, we here propose Deep SNP, a novel Deep Neural Network to learn from genomic data. Specifically, we used a manually curated dataset from 12 genomic single nucleotide polymorphism array (SNPa) profiles as truth-set and aimed at predicting the presence or absence of genomic breakpoints, an indicator of structural chromosomal variations, in windows of 40,000 probes. We compare our results with well-known neural network models as well as Rawcopy though this tool is designed to predict breakpoints and in addition genomic segments with high sensitivity. We show, that Deep SNP is capable of successfully predicting the presence or absence of a breakpoint in large genomic windows and outperforms state-of-the-art neural network models. Qualitative examples suggest that integration of a localization unit may enable breakpoint detection and prediction of genomic segments, even if the breakpoint coordinates were not provided for network training. These results warrant further evaluation of DeepSNP for breakpoint localization and subsequent calling of genomic segments.

Dynamic MRI enables a range of clinical applications, including cardiac function assessment, organ motion tracking, and radiotherapy guidance. However, fully sampling the dynamic k-space data is often infeasible due to time constraints and physiological motion such as respiratory and cardiac motion. This necessitates undersampling, which degrades the quality of reconstructed images. Poor image quality not only hinders visualization but also impairs the estimation of deformation fields, crucial for registering dynamic (moving) images to a static reference image. This registration enables tasks such as motion correction, treatment planning, and quantitative analysis in applications like cardiac imaging and MR-guided radiotherapy. To overcome the challenges posed by undersampling and motion, we introduce an end-to-end deep learning (DL) framework that integrates adaptive dynamic k-space sampling, reconstruction, and registration. Our approach begins with a DL-based adaptive sampling strategy, optimizing dynamic k-space acquisition to capture the most relevant data for each specific case. This is followed by a DL-based reconstruction module that produces images optimized for accurate deformation field estimation from the undersampled moving data. Finally, a registration module estimates the deformation fields aligning the reconstructed dynamic images with a static reference. The proposed framework is independent of specific reconstruction and registration modules allowing for plug-and-play integration of these components. The entire framework is jointly trained using a combination of supervised and unsupervised loss functions, enabling end-to-end optimization for improved performance across all components. Through controlled experiments and ablation studies, we validate each component, demonstrating that each choice contributes to robust motion estimation from undersampled dynamic data.

Lensless imaging stands out as a promising alternative to conventional lens-based systems, particularly in scenarios demanding ultracompact form factors and cost-effective architectures. However, such systems are fundamentally governed by the Point Spread Function (PSF), which dictates how a point source contributes to the final captured signal. Traditional lensless techniques often require explicit calibrations and extensive pre-processing, relying on static or approximate PSF models. These rigid strategies can result in limited adaptability to real-world challenges, including noise, system imperfections, and dynamic scene variations, thus impeding high-fidelity reconstruction. In this paper, we propose LensNet, an end-to-end deep learning framework that integrates spatial-domain and frequency-domain representations in a unified pipeline. Central to our approach is a learnable Coded Mask Simulator (CMS) that enables dynamic, data-driven estimation of the PSF during training, effectively mitigating the shortcomings of fixed or sparsely calibrated kernels. By embedding a Wiener filtering component, LensNet refines global structure and restores fine-scale details, thus alleviating the dependency on multiple handcrafted pre-processing steps. Extensive experiments demonstrate LensNet's robust performance and superior reconstruction quality compared to state-of-the-art methods, particularly in preserving high-frequency details and attenuating noise. The proposed framework establishes a novel convergence between physics-based modeling and data-driven learning, paving the way for more accurate, flexible, and practical lensless imaging solutions for applications ranging from miniature sensors to medical diagnostics. The link of code is https://github.com/baijiesong/Lensnet.

Handwriting-based gender classification is a well-researched problem that has been approached mainly by traditional machine learning techniques. In this paper, we propose a novel deep learning-based approach for this task. Specifically, we present a convolutional neural network (CNN), which performs automatic feature extraction from a given handwritten image, followed by classification of the writer's gender. Also, we introduce a new dataset of labeled handwritten samples, in Hebrew and English, of 405 participants. Comparing the gender classification accuracy on this dataset against human examiners, our results show that the proposed deep learning-based approach is substantially more accurate than that of humans.

We present a state-of-the-art speech recognition system developed using end-to-end deep learning. Our architecture is significantly simpler than traditional speech systems, which rely on laboriously engineered processing pipelines; these traditional systems also tend to perform poorly when used in noisy environments. In contrast, our system does not need hand-designed components to model background noise, reverberation, or speaker variation, but instead directly learns a function that is robust to such effects. We do not need a phoneme dictionary, nor even the concept of a "phoneme." Key to our approach is a well-optimized RNN training system that uses multiple GPUs, as well as a set of novel data synthesis techniques that allow us to efficiently obtain a large amount of varied data for training. Our system, called Deep Speech, outperforms previously published results on the widely studied Switchboard Hub5'00, achieving 16.0% error on the full test set. Deep Speech also handles challenging noisy environments better than widely used, state-of-the-art commercial speech systems.

Chess recognition is the task of extracting the chess piece configuration from a chessboard image. Current approaches use a pipeline of separate, independent, modules such as chessboard detection, square localization, and piece classification. Instead, we follow the deep learning philosophy and explore an end-to-end approach to directly predict the configuration from the image, thus avoiding the error accumulation of the sequential approaches and eliminating the need for intermediate annotations. Furthermore, we introduce a new dataset, Chess Recognition Dataset (ChessReD), that consists of 10,800 real photographs and their corresponding annotations. In contrast to existing datasets that are synthetically rendered and have only limited angles, ChessReD has photographs captured from various angles using smartphone cameras; a sensor choice made to ensure real-world applicability. Our approach in chess recognition on the introduced challenging benchmark dataset outperforms related approaches, successfully recognizing the chess pieces' configuration in 15.26% of ChessReD's test images. This accuracy may seem low, but it is ~7x better than the current state-of-the-art and reflects the difficulty of the problem. The code and data are available through: https://github.com/ThanosM97/end-to-end-chess-recognition.

Lipreading is the task of decoding text from the movement of a speaker's mouth. Traditional approaches separated the problem into two stages: designing or learning visual features, and prediction. More recent deep lipreading approaches are end-to-end trainable (Wand et al., 2016; Chung & Zisserman, 2016a). However, existing work on models trained end-to-end perform only word classification, rather than sentence-level sequence prediction. Studies have shown that human lipreading performance increases for longer words (Easton & Basala, 1982), indicating the importance of features capturing temporal context in an ambiguous communication channel. Motivated by this observation, we present LipNet, a model that maps a variable-length sequence of video frames to text, making use of spatiotemporal convolutions, a recurrent network, and the connectionist temporal classification loss, trained entirely end-to-end. To the best of our knowledge, LipNet is the first end-to-end sentence-level lipreading model that simultaneously learns spatiotemporal visual features and a sequence model. On the GRID corpus, LipNet achieves 95.2% accuracy in sentence-level, overlapped speaker split task, outperforming experienced human lipreaders and the previous 86.4% word-level state-of-the-art accuracy (Gergen et al., 2016).

In this paper, we present our contribution to ABAW facial expression challenge. We report the proposed system and the official challenge results adhering to the challenge protocol. Using end-to-end deep learning and benefiting from transfer learning approaches, we reached a test set challenge performance measure of 42.10%.

This review article is an attempt to survey all recent AI based techniques used to deal with major functions in This review paper presents a comprehensive overview of end-to-end deep learning frameworks used in the context of autonomous navigation, including obstacle detection, scene perception, path planning, and control. The paper aims to bridge the gap between autonomous navigation and deep learning by analyzing recent research studies and evaluating the implementation and testing of deep learning methods. It emphasizes the importance of navigation for mobile robots, autonomous vehicles, and unmanned aerial vehicles, while also acknowledging the challenges due to environmental complexity, uncertainty, obstacles, dynamic environments, and the need to plan paths for multiple agents. The review highlights the rapid growth of deep learning in engineering data science and its development of innovative navigation methods. It discusses recent interdisciplinary work related to this field and provides a brief perspective on the limitations, challenges, and potential areas of growth for deep learning methods in autonomous navigation. Finally, the paper summarizes the findings and practices at different stages, correlating existing and future methods, their applicability, scalability, and limitations. The review provides a valuable resource for researchers and practitioners working in the field of autonomous navigation and deep learning.

Iris recognition has been an active research area during last few decades, because of its wide applications in security, from airports to homeland security border control. Different features and algorithms have been proposed for iris recognition in the past. In this paper, we propose an end-to-end deep learning framework for iris recognition based on residual convolutional neural network (CNN), which can jointly learn the feature representation and perform recognition. We train our model on a well-known iris recognition dataset using only a few training images from each class, and show promising results and improvements over previous approaches. We also present a visualization technique which is able to detect the important areas in iris images which can mostly impact the recognition results. We believe this framework can be widely used for other biometrics recognition tasks, helping to have a more scalable and accurate systems.

Much of the world's most valued data is stored in relational databases and data warehouses, where the data is organized into many tables connected by primary-foreign key relations. However, building machine learning models using this data is both challenging and time consuming. The core problem is that no machine learning method is capable of learning on multiple tables interconnected by primary-foreign key relations. Current methods can only learn from a single table, so the data must first be manually joined and aggregated into a single training table, the process known as feature engineering. Feature engineering is slow, error prone and leads to suboptimal models. Here we introduce an end-to-end deep representation learning approach to directly learn on data laid out across multiple tables. We name our approach Relational Deep Learning (RDL). The core idea is to view relational databases as a temporal, heterogeneous graph, with a node for each row in each table, and edges specified by primary-foreign key links. Message Passing Graph Neural Networks can then automatically learn across the graph to extract representations that leverage all input data, without any manual feature engineering. Relational Deep Learning leads to more accurate models that can be built much faster. To facilitate research in this area, we develop RelBench, a set of benchmark datasets and an implementation of Relational Deep Learning. The data covers a wide spectrum, from discussions on Stack Exchange to book reviews on the Amazon Product Catalog. Overall, we define a new research area that generalizes graph machine learning and broadens its applicability to a wide set of AI use cases.

Deep Neural Networks (DNNs) are generated by sequentially performing linear and non-linear processes. Using a combination of linear and non-linear procedures is critical for generating a sufficiently deep feature space. The majority of non-linear operators are derivations of activation functions or pooling functions. Mathematical morphology is a branch of mathematics that provides non-linear operators for a variety of image processing problems. We investigate the utility of integrating these operations in an end-to-end deep learning framework in this paper. DNNs are designed to acquire a realistic representation for a particular job. Morphological operators give topological descriptors that convey salient information about the shapes of objects depicted in images. We propose a method based on meta-learning to incorporate morphological operators into DNNs. The learned architecture demonstrates how our novel morphological operations significantly increase DNN performance on various tasks, including picture classification and edge detection.

In-line with the success of deep learning on traditional recognition problem, several end-to-end deep models for zero-shot recognition have been proposed in the literature. These models are successful to predict a single unseen label given an input image, but does not scale to cases where multiple unseen objects are present. In this paper, we model this problem within the framework of Multiple Instance Learning (MIL). To the best of our knowledge, we propose the first end-to-end trainable deep MIL framework for the multi-label zero-shot tagging problem. Due to its novel design, the proposed framework has several interesting features: (1) Unlike previous deep MIL models, it does not use any off-line procedure (e.g., Selective Search or EdgeBoxes) for bag generation. (2) During test time, it can process any number of unseen labels given their semantic embedding vectors. (3) Using only seen labels per image as weak annotation, it can produce a bounding box for each predicted labels. We experiment with the NUS-WIDE dataset and achieve superior performance across conventional, zero-shot and generalized zero-shot tagging tasks.

Accurate anatomical labeling and analysis of the pulmonary structure and its surrounding anatomy from thoracic CT is getting increasingly important for understanding the etilogy of abnormalities or supporting targetted therapy and early interventions. Whilst lung and airway cell atlases have been attempted, there is a lack of fine-grained morphological atlases that are clinically deployable. In this work, we introduce AirMorph, a robust, end-to-end deep learning pipeline enabling fully automatic and comprehensive airway anatomical labeling at lobar, segmental, and subsegmental resolutions that can be used to create digital atlases of the lung. Evaluated across large-scale multi-center datasets comprising diverse pulmonary conditions, the AirMorph consistently outperformed existing segmentation and labeling methods in terms of accuracy, topological consistency, and completeness. To simplify clinical interpretation, we further introduce a compact anatomical signature quantifying critical morphological airway features, including stenosis, ectasia, tortuosity, divergence, length, and complexity. When applied to various pulmonary diseases such as pulmonary fibrosis, emphysema, atelectasis, consolidation, and reticular opacities, it demonstrates strong discriminative power, revealing disease-specific morphological patterns with high interpretability and explainability. Additionally, AirMorph supports efficient automated branching pattern analysis, potentially enhancing bronchoscopic navigation planning and procedural safety, offering a valuable clinical tool for improved diagnosis, targeted treatment, and personalized patient care.

In this work we design an end-to-end deep learning architecture for predicting, on Chest X-rays images (CXR), a multi-regional score conveying the degree of lung compromise in COVID-19 patients. Such semi-quantitative scoring system, namely Brixia~score, is applied in serial monitoring of such patients, showing significant prognostic value, in one of the hospitals that experienced one of the highest pandemic peaks in Italy. To solve such a challenging visual task, we adopt a weakly supervised learning strategy structured to handle different tasks (segmentation, spatial alignment, and score estimation) trained with a "from-the-part-to-the-whole" procedure involving different datasets. In particular, we exploit a clinical dataset of almost 5,000 CXR annotated images collected in the same hospital. Our BS-Net demonstrates self-attentive behavior and a high degree of accuracy in all processing stages. Through inter-rater agreement tests and a gold standard comparison, we show that our solution outperforms single human annotators in rating accuracy and consistency, thus supporting the possibility of using this tool in contexts of computer-assisted monitoring. Highly resolved (super-pixel level) explainability maps are also generated, with an original technique, to visually help the understanding of the network activity on the lung areas. We also consider other scores proposed in literature and provide a comparison with a recently proposed non-specific approach. We eventually test the performance robustness of our model on an assorted public COVID-19 dataset, for which we also provide Brixia~score annotations, observing good direct generalization and fine-tuning capabilities that highlight the portability of BS-Net in other clinical settings. The CXR dataset along with the source code and the trained model are publicly released for research purposes.

In this paper, we propose an end-to-end deep learning model, called E2Efold, for RNA secondary structure prediction which can effectively take into account the inherent constraints in the problem. The key idea of E2Efold is to directly predict the RNA base-pairing matrix, and use an unrolled algorithm for constrained programming as the template for deep architectures to enforce constraints. With comprehensive experiments on benchmark datasets, we demonstrate the superior performance of E2Efold: it predicts significantly better structures compared to previous SOTA (especially for pseudoknotted structures), while being as efficient as the fastest algorithms in terms of inference time.

Automated detection and segmentation of surgical devices, such as catheters or wires, in X-ray fluoroscopic images have the potential to enhance image guidance in minimally invasive heart surgeries. In this paper, we present a convolutional neural network model that integrates a resnet architecture with multiple prediction heads to achieve real-time, accurate localization of electrodes on catheters and catheter segmentation in an end-to-end deep learning framework. We also propose a multi-task learning strategy in which our model is trained to perform both accurate electrode detection and catheter segmentation simultaneously. A key challenge with this approach is achieving optimal performance for both tasks. To address this, we introduce a novel multi-level dynamic resource prioritization method. This method dynamically adjusts sample and task weights during training to effectively prioritize more challenging tasks, where task difficulty is inversely proportional to performance and evolves throughout the training process. Experiments on both public and private datasets have demonstrated that the accuracy of our method surpasses the existing state-of-the-art methods in both single segmentation task and in the detection and segmentation multi-task. Our approach achieves a good trade-off between accuracy and efficiency, making it well-suited for real-time surgical guidance applications.

Weed control is a critical challenge in modern agriculture, as weeds compete with crops for essential nutrient resources, significantly reducing crop yield and quality. Traditional weed control methods, including chemical and mechanical approaches, have real-life limitations such as associated environmental impact and efficiency. An emerging yet effective approach is laser weeding, which uses a laser beam as the stem cutter. Although there have been studies that use deep learning in weed recognition, its application in intelligent laser weeding still requires a comprehensive understanding. Thus, this study represents the first empirical investigation of weed recognition for laser weeding. To increase the efficiency of laser beam cut and avoid damaging the crops of interest, the laser beam shall be directly aimed at the weed root. Yet, weed stem detection remains an under-explored problem. We integrate the detection of crop and weed with the localization of weed stem into one end-to-end system. To train and validate the proposed system in a real-life scenario, we curate and construct a high-quality weed stem detection dataset with human annotations. The dataset consists of 7,161 high-resolution pictures collected in the field with annotations of 11,151 instances of weed. Experimental results show that the proposed system improves weeding accuracy by 6.7% and reduces energy cost by 32.3% compared to existing weed recognition systems.

In financial trading, return prediction is one of the foundation for a successful trading system. By the fast development of the deep learning in various areas such as graphical processing, natural language, it has also demonstrate significant edge in handling with financial data. While the success of the deep learning relies on huge amount of labeled sample, labeling each time/event as profitable or unprofitable, under the transaction cost, especially in the high-frequency trading world, suffers from serious label imbalance issue.In this paper, we adopts rigurious end-to-end deep learning framework with comprehensive label imbalance adjustment methods and succeed in predicting in high-frequency return in the Chinese future market. The code for our method is publicly available at https://github.com/RS2002/Label-Unbalance-in-High-Frequency-Trading .

While recent research has progressively overcome the low-resolution constraint of one-shot face video re-enactment with the help of StyleGAN's high-fidelity portrait generation, these approaches rely on at least one of the following: explicit 2D/3D priors, optical flow based warping as motion descriptors, off-the-shelf encoders, etc., which constrain their performance (e.g., inconsistent predictions, inability to capture fine facial details and accessories, poor generalization, artifacts). We propose an end-to-end framework for simultaneously supporting face attribute edits, facial motions and deformations, and facial identity control for video generation. It employs a hybrid latent-space that encodes a given frame into a pair of latents: Identity latent, W_{ID}, and Facial deformation latent, S_F, that respectively reside in the W+ and SS spaces of StyleGAN2. Thereby, incorporating the impressive editability-distortion trade-off of W+ and the high disentanglement properties of SS. These hybrid latents employ the StyleGAN2 generator to achieve high-fidelity face video re-enactment at 1024^2. Furthermore, the model supports the generation of realistic re-enactment videos with other latent-based semantic edits (e.g., beard, age, make-up, etc.). Qualitative and quantitative analyses performed against state-of-the-art methods demonstrate the superiority of the proposed approach.

Magnetization transfer contrast magnetic resonance fingerprinting (MTC-MRF) is a novel quantitative imaging technique that simultaneously measures several tissue parameters of semisolid macromolecule and free bulk water. In this study, we propose an Only-Train-Once MR fingerprinting (OTOM) framework that estimates the free bulk water and MTC tissue parameters from MR fingerprints regardless of MRF schedule, thereby avoiding time-consuming process such as generation of training dataset and network training according to each MRF schedule. A recurrent neural network is designed to cope with two types of variants of MRF schedules: 1) various lengths and 2) various patterns. Experiments on digital phantoms and in vivo data demonstrate that our approach can achieve accurate quantification for the water and MTC parameters with multiple MRF schedules. Moreover, the proposed method is in excellent agreement with the conventional deep learning and fitting methods. The flexible OTOM framework could be an efficient tissue quantification tool for various MRF protocols.

Grouping and recognition are important components of visual scene understanding, e.g., for object detection and semantic segmentation. With end-to-end deep learning systems, grouping of image regions usually happens implicitly via top-down supervision from pixel-level recognition labels. Instead, in this paper, we propose to bring back the grouping mechanism into deep networks, which allows semantic segments to emerge automatically with only text supervision. We propose a hierarchical Grouping Vision Transformer (GroupViT), which goes beyond the regular grid structure representation and learns to group image regions into progressively larger arbitrary-shaped segments. We train GroupViT jointly with a text encoder on a large-scale image-text dataset via contrastive losses. With only text supervision and without any pixel-level annotations, GroupViT learns to group together semantic regions and successfully transfers to the task of semantic segmentation in a zero-shot manner, i.e., without any further fine-tuning. It achieves a zero-shot accuracy of 52.3% mIoU on the PASCAL VOC 2012 and 22.4% mIoU on PASCAL Context datasets, and performs competitively to state-of-the-art transfer-learning methods requiring greater levels of supervision. We open-source our code at https://github.com/NVlabs/GroupViT .

Ancillaries have become a major source of revenue and profitability in the travel industry. Yet, conventional pricing strategies are based on business rules that are poorly optimized and do not respond to changing market conditions. This paper describes the dynamic pricing model developed by Deepair solutions, an AI technology provider for travel suppliers. We present a pricing model that provides dynamic pricing recommendations specific to each customer interaction and optimizes expected revenue per customer. The unique nature of personalized pricing provides the opportunity to search over the market space to find the optimal price-point of each ancillary for each customer, without violating customer privacy. In this paper, we present and compare three approaches for dynamic pricing of ancillaries, with increasing levels of sophistication: (1) a two-stage forecasting and optimization model using a logistic mapping function; (2) a two-stage model that uses a deep neural network for forecasting, coupled with a revenue maximization technique using discrete exhaustive search; (3) a single-stage end-to-end deep neural network that recommends the optimal price. We describe the performance of these models based on both offline and online evaluations. We also measure the real-world business impact of these approaches by deploying them in an A/B test on an airline's internet booking website. We show that traditional machine learning techniques outperform human rule-based approaches in an online setting by improving conversion by 36% and revenue per offer by 10%. We also provide results for our offline experiments which show that deep learning algorithms outperform traditional machine learning techniques for this problem. Our end-to-end deep learning model is currently being deployed by the airline in their booking system.

Deep learning (DL) based semantic communication methods have been explored for the efficient transmission of images, text, and speech in recent years. In contrast to traditional wireless communication methods that focus on the transmission of abstract symbols, semantic communication approaches attempt to achieve better transmission efficiency by only sending the semantic-related information of the source data. In this paper, we consider semantic-oriented speech transmission which transmits only the semantic-relevant information over the channel for the speech recognition task, and a compact additional set of semantic-irrelevant information for the speech reconstruction task. We propose a novel end-to-end DL-based transceiver which extracts and encodes the semantic information from the input speech spectrums at the transmitter and outputs the corresponding transcriptions from the decoded semantic information at the receiver. For the speech to speech transmission, we further include a CTC alignment module that extracts a small number of additional semantic-irrelevant but speech-related information for the better reconstruction of the original speech signals at the receiver. The simulation results confirm that our proposed method outperforms current methods in terms of the accuracy of the predicted text for the speech to text transmission and the quality of the recovered speech signals for the speech to speech transmission, and significantly improves transmission efficiency. More specifically, the proposed method only sends 16% of the amount of the transmitted symbols required by the existing methods while achieving about 10% reduction in WER for the speech to text transmission. For the speech to speech transmission, it results in an even more remarkable improvement in terms of transmission efficiency with only 0.2% of the amount of the transmitted symbols required by the existing method.

In this paper, we propose a dual-stage architecture for bandwidth extension (BWE) increasing the effective sampling rate of speech signals from 8 kHz to 48 kHz. Unlike existing end-to-end deep learning models, our proposed method explicitly models BWE using excitation and linear time-varying (LTV) filter stages. The excitation stage broadens the spectrum of the input, while the filtering stage properly shapes it based on outputs from an acoustic feature predictor. To this end, an acoustic feature loss term can implicitly promote the excitation subnetwork to produce white spectra in the upper frequency band to be synthesized. Experimental results demonstrate that the added inductive bias provided by our approach can improve upon BWE results using the generators from both SEANet or HiFi-GAN as exciters, and that our means of adapting processing with acoustic feature predictions is more effective than that used in HiFi-GAN-2. Secondary contributions include extensions of the SEANet model to accommodate local conditioning information, as well as the application of HiFi-GAN-2 for the BWE problem.

We present an end-to-end deep learning segmentation method by combining a 3D UNet architecture with a graph neural network (GNN) model. In this approach, the convolutional layers at the deepest level of the UNet are replaced by a GNN-based module with a series of graph convolutions. The dense feature maps at this level are transformed into a graph input to the GNN module. The incorporation of graph convolutions in the UNet provides nodes in the graph with information that is based on node connectivity, in addition to the local features learnt through the downsampled paths. This information can help improve segmentation decisions. By stacking several graph convolution layers, the nodes can access higher order neighbourhood information without substantial increase in computational expense. We propose two types of node connectivity in the graph adjacency: i) one predefined and based on a regular node neighbourhood, and ii) one dynamically computed during training and using the nearest neighbour nodes in the feature space. We have applied this method to the task of segmenting the airway tree from chest CT scans. Experiments have been performed on 32 CTs from the Danish Lung Cancer Screening Trial dataset. We evaluate the performance of the UNet-GNN models with two types of graph adjacency and compare it with the baseline UNet.

We present RigNet, an end-to-end automated method for producing animation rigs from input character models. Given an input 3D model representing an articulated character, RigNet predicts a skeleton that matches the animator expectations in joint placement and topology. It also estimates surface skin weights based on the predicted skeleton. Our method is based on a deep architecture that directly operates on the mesh representation without making assumptions on shape class and structure. The architecture is trained on a large and diverse collection of rigged models, including their mesh, skeletons and corresponding skin weights. Our evaluation is three-fold: we show better results than prior art when quantitatively compared to animator rigs; qualitatively we show that our rigs can be expressively posed and animated at multiple levels of detail; and finally, we evaluate the impact of various algorithm choices on our output rigs.

Urbanization, climate change, and agricultural stress are increasing the demand for precise and timely environmental monitoring. Land Surface Temperature (LST) is a key variable in this context and is retrieved from remote sensing satellites. However, these systems face a trade-off between spatial and temporal resolution. While spatio-temporal fusion methods offer promising solutions, few have addressed the estimation of daily LST at 10 m resolution. In this study, we present WGAST, a Weakly-Supervised Generative Network for Daily 10 m LST Estimation via Spatio-Temporal Fusion of Terra MODIS, Landsat 8, and Sentinel-2. WGAST is the first end-to-end deep learning framework designed for this task. It adopts a conditional generative adversarial architecture, with a generator composed of four stages: feature extraction, fusion, LST reconstruction, and noise suppression. The first stage employs a set of encoders to extract multi-level latent representations from the inputs, which are then fused in the second stage using cosine similarity, normalization, and temporal attention mechanisms. The third stage decodes the fused features into high-resolution LST, followed by a Gaussian filter to suppress high-frequency noise. Training follows a weakly supervised strategy based on physical averaging principles and reinforced by a PatchGAN discriminator. Experiments demonstrate that WGAST outperforms existing methods in both quantitative and qualitative evaluations. Compared to the best-performing baseline, on average, WGAST reduces RMSE by 17.18% and improves SSIM by 11.00%. Furthermore, WGAST is robust to cloud-induced LST and effectively captures fine-scale thermal patterns, as validated against 33 ground-based sensors. The code is available at https://github.com/Sofianebouaziz1/WGAST.git.

The conversion from 2D X-ray to 3D shape holds significant potential for improving diagnostic efficiency and safety. However, existing reconstruction methods often rely on hand-crafted features, manual intervention, and prior knowledge, resulting in unstable shape errors and additional processing costs. In this paper, we introduce Swin-X2S, an end-to-end deep learning method for directly reconstructing 3D segmentation and labeling from 2D biplanar orthogonal X-ray images. Swin-X2S employs an encoder-decoder architecture: the encoder leverages 2D Swin Transformer for X-ray information extraction, while the decoder employs 3D convolution with cross-attention to integrate structural features from orthogonal views. A dimension-expanding module is introduced to bridge the encoder and decoder, ensuring a smooth conversion from 2D pixels to 3D voxels. We evaluate proposed method through extensive qualitative and quantitative experiments across nine publicly available datasets covering four anatomies (femur, hip, spine, and rib), with a total of 54 categories. Significant improvements over previous methods have been observed not only in the segmentation and labeling metrics but also in the clinically relevant parameters that are of primary concern in practical applications, which demonstrates the promise of Swin-X2S to provide an effective option for anatomical shape reconstruction in clinical scenarios. Code implementation is available at: https://github.com/liukuan5625/Swin-X2S.

Tables organize valuable content in a concise and compact representation. This content is extremely valuable for systems such as search engines, Knowledge Graph's, etc, since they enhance their predictive capabilities. Unfortunately, tables come in a large variety of shapes and sizes. Furthermore, they can have complex column/row-header configurations, multiline rows, different variety of separation lines, missing entries, etc. As such, the correct identification of the table-structure from an image is a non-trivial task. In this paper, we present a new table-structure identification model. The latter improves the latest end-to-end deep learning model (i.e. encoder-dual-decoder from PubTabNet) in two significant ways. First, we introduce a new object detection decoder for table-cells. In this way, we can obtain the content of the table-cells from programmatic PDF's directly from the PDF source and avoid the training of the custom OCR decoders. This architectural change leads to more accurate table-content extraction and allows us to tackle non-english tables. Second, we replace the LSTM decoders with transformer based decoders. This upgrade improves significantly the previous state-of-the-art tree-editing-distance-score (TEDS) from 91% to 98.5% on simple tables and from 88.7% to 95% on complex tables.

Book image rectification presents unique challenges in document image processing due to complex geometric distortions from binding constraints, where left and right pages exhibit distinctly asymmetric curvature patterns. However, existing single-page document image rectification methods fail to capture the coupled geometric relationships between adjacent pages in books. In this work, we introduce BookNet, the first end-to-end deep learning framework specifically designed for dual-page book image rectification. BookNet adopts a dual-branch architecture with cross-page attention mechanisms, enabling it to estimate warping flows for both individual pages and the complete book spread, explicitly modeling how left and right pages influence each other. Moreover, to address the absence of specialized datasets, we present Book3D, a large-scale synthetic dataset for training, and Book100, a comprehensive real-world benchmark for evaluation. Extensive experiments demonstrate that BookNet outperforms existing state-of-the-art methods on book image rectification. Code and dataset will be made publicly available.

Law enforcement and city safety are significantly impacted by detecting violent incidents in surveillance systems. Although modern (smart) cameras are widely available and affordable, such technological solutions are impotent in most instances. Furthermore, personnel monitoring CCTV recordings frequently show a belated reaction, resulting in the potential cause of catastrophe to people and property. Thus automated detection of violence for swift actions is very crucial. The proposed solution uses a novel end-to-end deep learning-based video vision transformer (ViViT) that can proficiently discern fights, hostile movements, and violent events in video sequences. The study presents utilizing a data augmentation strategy to overcome the downside of weaker inductive biasness while training vision transformers on a smaller training datasets. The evaluated results can be subsequently sent to local concerned authority, and the captured video can be analyzed. In comparison to state-of-theart (SOTA) approaches the proposed method achieved auspicious performance on some of the challenging benchmark datasets.

Understanding non-human primate behavior is crucial for improving animal welfare, modeling social behavior, and gaining insights into both distinctly human and shared behaviors. Despite recent advances in computer vision, automated analysis of primate behavior remains challenging due to the complexity of their social interactions and the lack of specialized algorithms. Existing methods often struggle with the nuanced behaviors and frequent occlusions characteristic of primate social dynamics. This study aims to develop an effective method for automated detection, tracking, and recognition of chimpanzee behaviors in video footage. Here we show that our proposed method, AlphaChimp, an end-to-end approach that simultaneously detects chimpanzee positions and estimates behavior categories from videos, significantly outperforms existing methods in behavior recognition. AlphaChimp achieves approximately 10% higher tracking accuracy and a 20% improvement in behavior recognition compared to state-of-the-art methods, particularly excelling in the recognition of social behaviors. This superior performance stems from AlphaChimp's innovative architecture, which integrates temporal feature fusion with a Transformer-based self-attention mechanism, enabling more effective capture and interpretation of complex social interactions among chimpanzees. Our approach bridges the gap between computer vision and primatology, enhancing technical capabilities and deepening our understanding of primate communication and sociality. We release our code and models and hope this will facilitate future research in animal social dynamics. This work contributes to ethology, cognitive science, and artificial intelligence, offering new perspectives on social intelligence.

We introduce Pixel-aligned Implicit Function (PIFu), a highly effective implicit representation that locally aligns pixels of 2D images with the global context of their corresponding 3D object. Using PIFu, we propose an end-to-end deep learning method for digitizing highly detailed clothed humans that can infer both 3D surface and texture from a single image, and optionally, multiple input images. Highly intricate shapes, such as hairstyles, clothing, as well as their variations and deformations can be digitized in a unified way. Compared to existing representations used for 3D deep learning, PIFu can produce high-resolution surfaces including largely unseen regions such as the back of a person. In particular, it is memory efficient unlike the voxel representation, can handle arbitrary topology, and the resulting surface is spatially aligned with the input image. Furthermore, while previous techniques are designed to process either a single image or multiple views, PIFu extends naturally to arbitrary number of views. We demonstrate high-resolution and robust reconstructions on real world images from the DeepFashion dataset, which contains a variety of challenging clothing types. Our method achieves state-of-the-art performance on a public benchmark and outperforms the prior work for clothed human digitization from a single image.

Hyperspectral image (HSI) classification is widely used for the analysis of remotely sensed images. Hyperspectral imagery includes varying bands of images. Convolutional Neural Network (CNN) is one of the most frequently used deep learning based methods for visual data processing. The use of CNN for HSI classification is also visible in recent works. These approaches are mostly based on 2D CNN. Whereas, the HSI classification performance is highly dependent on both spatial and spectral information. Very few methods have utilized the 3D CNN because of increased computational complexity. This letter proposes a Hybrid Spectral Convolutional Neural Network (HybridSN) for HSI classification. Basically, the HybridSN is a spectral-spatial 3D-CNN followed by spatial 2D-CNN. The 3D-CNN facilitates the joint spatial-spectral feature representation from a stack of spectral bands. The 2D-CNN on top of the 3D-CNN further learns more abstract level spatial representation. Moreover, the use of hybrid CNNs reduces the complexity of the model compared to 3D-CNN alone. To test the performance of this hybrid approach, very rigorous HSI classification experiments are performed over Indian Pines, Pavia University and Salinas Scene remote sensing datasets. The results are compared with the state-of-the-art hand-crafted as well as end-to-end deep learning based methods. A very satisfactory performance is obtained using the proposed HybridSN for HSI classification. The source code can be found at https://github.com/gokriznastic/HybridSN.

Image super-resolution is one of the most popular computer vision problems with many important applications to mobile devices. While many solutions have been proposed for this task, they are usually not optimized even for common smartphone AI hardware, not to mention more constrained smart TV platforms that are often supporting INT8 inference only. To address this problem, we introduce the first Mobile AI challenge, where the target is to develop an end-to-end deep learning-based image super-resolution solutions that can demonstrate a real-time performance on mobile or edge NPUs. For this, the participants were provided with the DIV2K dataset and trained quantized models to do an efficient 3X image upscaling. The runtime of all models was evaluated on the Synaptics VS680 Smart Home board with a dedicated NPU capable of accelerating quantized neural networks. The proposed solutions are fully compatible with all major mobile AI accelerators and are capable of reconstructing Full HD images under 40-60 ms while achieving high fidelity results. A detailed description of all models developed in the challenge is provided in this paper.

Building a conversational embodied agent to execute real-life tasks has been a long-standing yet quite challenging research goal, as it requires effective human-agent communication, multi-modal understanding, long-range sequential decision making, etc. Traditional symbolic methods have scaling and generalization issues, while end-to-end deep learning models suffer from data scarcity and high task complexity, and are often hard to explain. To benefit from both worlds, we propose JARVIS, a neuro-symbolic commonsense reasoning framework for modular, generalizable, and interpretable conversational embodied agents. First, it acquires symbolic representations by prompting large language models (LLMs) for language understanding and sub-goal planning, and by constructing semantic maps from visual observations. Then the symbolic module reasons for sub-goal planning and action generation based on task- and action-level common sense. Extensive experiments on the TEACh dataset validate the efficacy and efficiency of our JARVIS framework, which achieves state-of-the-art (SOTA) results on all three dialog-based embodied tasks, including Execution from Dialog History (EDH), Trajectory from Dialog (TfD), and Two-Agent Task Completion (TATC) (e.g., our method boosts the unseen Success Rate on EDH from 6.1\% to 15.8\%). Moreover, we systematically analyze the essential factors that affect the task performance and also demonstrate the superiority of our method in few-shot settings. Our JARVIS model ranks first in the Alexa Prize SimBot Public Benchmark Challenge.

The caliber and configuration of retinal blood vessels serve as important biomarkers for various diseases and medical conditions. A thorough analysis of the retinal vasculature requires the segmentation of the blood vessels and their classification into arteries and veins, typically performed on color fundus images obtained by retinography. However, manually performing these tasks is labor-intensive and prone to human error. While several automated methods have been proposed to address this task, the current state of art faces challenges due to manifest classification errors affecting the topological consistency of segmentation maps. In this work, we introduce RRWNet, a novel end-to-end deep learning framework that addresses this limitation. The framework consists of a fully convolutional neural network that recursively refines semantic segmentation maps, correcting manifest classification errors and thus improving topological consistency. In particular, RRWNet is composed of two specialized subnetworks: a Base subnetwork that generates base segmentation maps from the input images, and a Recursive Refinement subnetwork that iteratively and recursively improves these maps. Evaluation on three different public datasets demonstrates the state-of-the-art performance of the proposed method, yielding more topologically consistent segmentation maps with fewer manifest classification errors than existing approaches. In addition, the Recursive Refinement module within RRWNet proves effective in post-processing segmentation maps from other methods, further demonstrating its potential. The model code, weights, and predictions will be publicly available at https://github.com/j-morano/rrwnet.

End-to-end deep reinforcement learning (DRL) for quadrotor control promises many benefits -- easy deployment, task generalization and real-time execution capability. Prior end-to-end DRL-based methods have showcased the ability to deploy learned controllers onto single quadrotors or quadrotor teams maneuvering in simple, obstacle-free environments. However, the addition of obstacles increases the number of possible interactions exponentially, thereby increasing the difficulty of training RL policies. In this work, we propose an end-to-end DRL approach to control quadrotor swarms in environments with obstacles. We provide our agents a curriculum and a replay buffer of the clipped collision episodes to improve performance in obstacle-rich environments. We implement an attention mechanism to attend to the neighbor robots and obstacle interactions - the first successful demonstration of this mechanism on policies for swarm behavior deployed on severely compute-constrained hardware. Our work is the first work that demonstrates the possibility of learning neighbor-avoiding and obstacle-avoiding control policies trained with end-to-end DRL that transfers zero-shot to real quadrotors. Our approach scales to 32 robots with 80% obstacle density in simulation and 8 robots with 20% obstacle density in physical deployment. Video demonstrations are available on the project website at: https://sites.google.com/view/obst-avoid-swarm-rl.

We demonstrate the possibility of learning drone swarm controllers that are zero-shot transferable to real quadrotors via large-scale multi-agent end-to-end reinforcement learning. We train policies parameterized by neural networks that are capable of controlling individual drones in a swarm in a fully decentralized manner. Our policies, trained in simulated environments with realistic quadrotor physics, demonstrate advanced flocking behaviors, perform aggressive maneuvers in tight formations while avoiding collisions with each other, break and re-establish formations to avoid collisions with moving obstacles, and efficiently coordinate in pursuit-evasion tasks. We analyze, in simulation, how different model architectures and parameters of the training regime influence the final performance of neural swarms. We demonstrate the successful deployment of the model learned in simulation to highly resource-constrained physical quadrotors performing station keeping and goal swapping behaviors. Code and video demonstrations are available on the project website at https://sites.google.com/view/swarm-rl.

Accurate prediction of knee osteoarthritis (KOA) progression from structural MRI has a potential to enhance disease understanding and support clinical trials. Prior art focused on manually designed imaging biomarkers, which may not fully exploit all disease-related information present in MRI scan. In contrast, our method learns relevant representations from raw data end-to-end using Deep Learning, and uses them for progression prediction. The method employs a 2D CNN to process the data slice-wise and aggregate the extracted features using a Transformer. Evaluated on a large cohort (n=4,866), the proposed method outperforms conventional 2D and 3D CNN-based models and achieves average precision of 0.58pm0.03 and ROC AUC of 0.78pm0.01. This paper sets a baseline on end-to-end KOA progression prediction from structural MRI. Our code is publicly available at https://github.com/MIPT-Oulu/OAProgressionMR.

Early cavemen relied on gestures, vocalizations, and simple signals to coordinate, plan, avoid predators, and share resources. Today, humans collaborate using complex languages to achieve remarkable results. What drives this evolution in communication? How does language emerge, adapt, and become vital for teamwork? Understanding the origins of language remains a challenge. A leading hypothesis in linguistics and anthropology posits that language evolved to meet the ecological and social demands of early human cooperation. Language did not arise in isolation, but through shared survival goals. Inspired by this view, we investigate the emergence of language in multi-agent Foraging Games. These environments are designed to reflect the cognitive and ecological constraints believed to have influenced the evolution of communication. Agents operate in a shared grid world with only partial knowledge about other agents and the environment, and must coordinate to complete games like picking up high-value targets or executing temporally ordered actions. Using end-to-end deep reinforcement learning, agents learn both actions and communication strategies from scratch. We find that agents develop communication protocols with hallmark features of natural language: arbitrariness, interchangeability, displacement, cultural transmission, and compositionality. We quantify each property and analyze how different factors, such as population size and temporal dependencies, shape specific aspects of the emergent language. Our framework serves as a platform for studying how language can evolve from partial observability, temporal reasoning, and cooperative goals in embodied multi-agent settings. We will release all data, code, and models publicly.

This paper describes EMBER: a labeled benchmark dataset for training machine learning models to statically detect malicious Windows portable executable files. The dataset includes features extracted from 1.1M binary files: 900K training samples (300K malicious, 300K benign, 300K unlabeled) and 200K test samples (100K malicious, 100K benign). To accompany the dataset, we also release open source code for extracting features from additional binaries so that additional sample features can be appended to the dataset. This dataset fills a void in the information security machine learning community: a benign/malicious dataset that is large, open and general enough to cover several interesting use cases. We enumerate several use cases that we considered when structuring the dataset. Additionally, we demonstrate one use case wherein we compare a baseline gradient boosted decision tree model trained using LightGBM with default settings to MalConv, a recently published end-to-end (featureless) deep learning model for malware detection. Results show that even without hyper-parameter optimization, the baseline EMBER model outperforms MalConv. The authors hope that the dataset, code and baseline model provided by EMBER will help invigorate machine learning research for malware detection, in much the same way that benchmark datasets have advanced computer vision research.

In the past few years, the field of computer vision has gone through a revolution fueled mainly by the advent of large datasets and the adoption of deep convolutional neural networks for end-to-end learning. The person re-identification subfield is no exception to this. Unfortunately, a prevailing belief in the community seems to be that the triplet loss is inferior to using surrogate losses (classification, verification) followed by a separate metric learning step. We show that, for models trained from scratch as well as pretrained ones, using a variant of the triplet loss to perform end-to-end deep metric learning outperforms most other published methods by a large margin.

Visual tracking is intrinsically a temporal problem. Discriminative Correlation Filters (DCF) have demonstrated excellent performance for high-speed generic visual object tracking. Built upon their seminal work, there has been a plethora of recent improvements relying on convolutional neural network (CNN) pretrained on ImageNet as a feature extractor for visual tracking. However, most of their works relying on ad hoc analysis to design the weights for different layers either using boosting or hedging techniques as an ensemble tracker. In this paper, we go beyond the conventional DCF framework and propose a Kernalised Multi-resolution Convnet (KMC) formulation that utilises hierarchical response maps to directly output the target movement. When directly deployed the learnt network to predict the unseen challenging UAV tracking dataset without any weight adjustment, the proposed model consistently achieves excellent tracking performance. Moreover, the transfered multi-reslution CNN renders it possible to be integrated into the RNN temporal learning framework, therefore opening the door on the end-to-end temporal deep learning (TDL) for visual tracking.

We present SURE-Score: an approach for learning score-based generative models using training samples corrupted by additive Gaussian noise. When a large training set of clean samples is available, solving inverse problems via score-based (diffusion) generative models trained on the underlying fully-sampled data distribution has recently been shown to outperform end-to-end supervised deep learning. In practice, such a large collection of training data may be prohibitively expensive to acquire in the first place. In this work, we present an approach for approximately learning a score-based generative model of the clean distribution, from noisy training data. We formulate and justify a novel loss function that leverages Stein's unbiased risk estimate to jointly denoise the data and learn the score function via denoising score matching, while using only the noisy samples. We demonstrate the generality of SURE-Score by learning priors and applying posterior sampling to ill-posed inverse problems in two practical applications from different domains: compressive wireless multiple-input multiple-output channel estimation and accelerated 2D multi-coil magnetic resonance imaging reconstruction, where we demonstrate competitive reconstruction performance when learning at signal-to-noise ratio values of 0 and 10 dB, respectively.

The performance of deep network learning strongly depends on the choice of the non-linear activation function associated with each neuron. However, deciding on the best activation is non-trivial, and the choice depends on the architecture, hyper-parameters, and even on the dataset. Typically these activations are fixed by hand before training. Here, we demonstrate how to eliminate the reliance on first picking fixed activation functions by using flexible parametric rational functions instead. The resulting Pad\'e Activation Units (PAUs) can both approximate common activation functions and also learn new ones while providing compact representations. Our empirical evidence shows that end-to-end learning deep networks with PAUs can increase the predictive performance. Moreover, PAUs pave the way to approximations with provable robustness. https://github.com/ml-research/pau

Medical research generates a large number of publications with the PubMed database already containing >35 million research articles. Integration of the knowledge scattered across this large body of literature could provide key insights into physiological mechanisms and disease processes leading to novel medical interventions. However, it is a great challenge for researchers to utilize this information in full since the scale and complexity of the data greatly surpasses human processing abilities. This becomes especially problematic in cases of extreme urgency like the COVID-19 pandemic. Automated text mining can help extract and connect information from the large body of medical research articles. The first step in text mining is typically the identification of specific classes of keywords (e.g., all protein or disease names), so called Named Entity Recognition (NER). Here we present an end-to-end pipeline for NER of typical entities found in medical research articles, including diseases, cells, chemicals, genes/proteins, and species. The pipeline can access and process large medical research article collections (PubMed, CORD-19) or raw text and incorporates a series of deep learning models fine-tuned on the HUNER corpora collection. In addition, the pipeline can perform dictionary-based NER related to COVID-19 and other medical topics. Users can also load their own NER models and dictionaries to include additional entities. The output consists of publication-ready ranked lists and graphs of detected entities and files containing the annotated texts. An associated script allows rapid inspection of the results for specific entities of interest. As model use cases, the pipeline was deployed on two collections of autophagy-related abstracts from PubMed and on the CORD19 dataset, a collection of 764 398 research article abstracts related to COVID-19.

The performance of advanced materials for extreme environments is underpinned by their microstructure, including the size and distribution of reinforcing phases. Chromium-based superalloys are a recently proposed alternative to conventional face-centred-cubic superalloys for high-temperature applications, such as Concentrated Solar Power, and their development requires efficient measurement of precipitate volume fraction and size distribution from electron microscopy images. Traditional fixed-threshold image processing is sensitive to background noise, generalises poorly across materials, and requires substantial manual measurement effort. To address these bottlenecks, this study proposes DT-SegNet, an end-to-end two-stage deep learning scheme based on YOLOv5 and SegFormer for object detection and segmentation in electron microscopy images. The approach combines the training efficiency of convolutional neural networks at the detection stage with the segmentation accuracy of a Vision Transformer. Numerical experiments show that DT-SegNet substantially outperforms state-of-the-art segmentation tools offered by Weka and ilastik across metrics including accuracy, precision, recall, and F1-score. The model provides a useful tool for alloy-development microstructure examinations and helps address the large datasets associated with high-throughput alloy development.

With the increasing legalization of medical and recreational use of cannabis, more research is needed to understand the association between depression and consumer behavior related to cannabis consumption. Big social media data has potential to provide deeper insights about these associations to public health analysts. In this interdisciplinary study, we demonstrate the value of incorporating domain-specific knowledge in the learning process to identify the relationships between cannabis use and depression. We develop an end-to-end knowledge infused deep learning framework (Gated-K-BERT) that leverages the pre-trained BERT language representation model and domain-specific declarative knowledge source (Drug Abuse Ontology (DAO)) to jointly extract entities and their relationship using gated fusion sharing mechanism. Our model is further tailored to provide more focus to the entities mention in the sentence through entity-position aware attention layer, where ontology is used to locate the target entities position. Experimental results show that inclusion of the knowledge-aware attentive representation in association with BERT can extract the cannabis-depression relationship with better coverage in comparison to the state-of-the-art relation extractor.

Nowadays, time series forecasting is predominantly approached through the end-to-end training of deep learning architectures using error-based objectives. While this is effective at minimizing average loss, it encourages the encoder to discard informative yet extreme patterns. This results in smooth predictions and temporal representations that poorly capture salient dynamics. To address this issue, we propose ReGuider, a plug-in method that can be seamlessly integrated into any forecasting architecture. ReGuider leverages pretrained time series foundation models as semantic teachers. During training, the input sequence is processed together by the target forecasting model and the pretrained model. Rather than using the pretrained model's outputs directly, we extract its intermediate embeddings, which are rich in temporal and semantic information, and align them with the target model's encoder embeddings through representation-level supervision. This alignment process enables the encoder to learn more expressive temporal representations, thereby improving the accuracy of downstream forecasting. Extensive experimentation across diverse datasets and architectures demonstrates that our ReGuider consistently improves forecasting performance, confirming its effectiveness and versatility.

There has been much interest in deploying deep learning algorithms on low-powered devices, including smartphones, drones, and medical sensors. However, full-scale deep neural networks are often too resource-intensive in terms of energy and storage. As a result, the bulk part of the machine learning operation is therefore often carried out on an edge server, where the data is compressed and transmitted. However, compressing data (such as images) leads to transmitting information irrelevant to the supervised task. Another popular approach is to split the deep network between the device and the server while compressing intermediate features. To date, however, such split computing strategies have barely outperformed the aforementioned naive data compression baselines due to their inefficient approaches to feature compression. This paper adopts ideas from knowledge distillation and neural image compression to compress intermediate feature representations more efficiently. Our supervised compression approach uses a teacher model and a student model with a stochastic bottleneck and learnable prior for entropy coding (Entropic Student). We compare our approach to various neural image and feature compression baselines in three vision tasks and found that it achieves better supervised rate-distortion performance while maintaining smaller end-to-end latency. We furthermore show that the learned feature representations can be tuned to serve multiple downstream tasks.

We present an end-to-end learning method for chess, relying on deep neural networks. Without any a priori knowledge, in particular without any knowledge regarding the rules of chess, a deep neural network is trained using a combination of unsupervised pretraining and supervised training. The unsupervised training extracts high level features from a given position, and the supervised training learns to compare two chess positions and select the more favorable one. The training relies entirely on datasets of several million chess games, and no further domain specific knowledge is incorporated. The experiments show that the resulting neural network (referred to as DeepChess) is on a par with state-of-the-art chess playing programs, which have been developed through many years of manual feature selection and tuning. DeepChess is the first end-to-end machine learning-based method that results in a grandmaster-level chess playing performance.

Deep Learning (DL) has the potential to optimize machine learning in both the scientific and clinical communities. However, greater expertise is required to develop DL algorithms, and the variability of implementations hinders their reproducibility, translation, and deployment. Here we present the community-driven Generally Nuanced Deep Learning Framework (GaNDLF), with the goal of lowering these barriers. GaNDLF makes the mechanism of DL development, training, and inference more stable, reproducible, interpretable, and scalable, without requiring an extensive technical background. GaNDLF aims to provide an end-to-end solution for all DL-related tasks in computational precision medicine. We demonstrate the ability of GaNDLF to analyze both radiology and histology images, with built-in support for k-fold cross-validation, data augmentation, multiple modalities and output classes. Our quantitative performance evaluation on numerous use cases, anatomies, and computational tasks supports GaNDLF as a robust application framework for deployment in clinical workflows.

There is an increasing need to bring machine learning to a wide diversity of hardware devices. Current frameworks rely on vendor-specific operator libraries and optimize for a narrow range of server-class GPUs. Deploying workloads to new platforms -- such as mobile phones, embedded devices, and accelerators (e.g., FPGAs, ASICs) -- requires significant manual effort. We propose TVM, a compiler that exposes graph-level and operator-level optimizations to provide performance portability to deep learning workloads across diverse hardware back-ends. TVM solves optimization challenges specific to deep learning, such as high-level operator fusion, mapping to arbitrary hardware primitives, and memory latency hiding. It also automates optimization of low-level programs to hardware characteristics by employing a novel, learning-based cost modeling method for rapid exploration of code optimizations. Experimental results show that TVM delivers performance across hardware back-ends that are competitive with state-of-the-art, hand-tuned libraries for low-power CPU, mobile GPU, and server-class GPUs. We also demonstrate TVM's ability to target new accelerator back-ends, such as the FPGA-based generic deep learning accelerator. The system is open sourced and in production use inside several major companies.

This paper attempts to analyze the effectiveness of deep learning for tabular data processing. It is believed that decision trees and their ensembles is the leading method in this domain, and deep neural networks must be content with computer vision and so on. But the deep neural network is a framework for building gradient-based hierarchical representations, and this key feature should be able to provide the best processing of generic structured (tabular) data, not just image matrices and audio spectrograms. This problem is considered through the prism of the Weather Prediction track in the Yandex Shifts challenge (in other words, the Yandex Shifts Weather task). This task is a variant of the classical tabular data regression problem. It is also connected with another important problem: generalization and uncertainty in machine learning. This paper proposes an end-to-end algorithm for solving the problem of regression with uncertainty on tabular data, which is based on the combination of four ideas: 1) deep ensemble of self-normalizing neural networks, 2) regression as parameter estimation of the Gaussian target error distribution, 3) hierarchical multitask learning, and 4) simple data preprocessing. Three modifications of the proposed algorithm form the top-3 leaderboard of the Yandex Shifts Weather challenge respectively. This paper considers that this success has occurred due to the fundamental properties of the deep learning algorithm, and tries to prove this.

Agentic systems built on large language models (LLMs) offer promising capabilities for automating complex workflows in healthcare AI. We introduce mAIstro, an open-source, autonomous multi-agentic framework for end-to-end development and deployment of medical AI models. The system orchestrates exploratory data analysis, radiomic feature extraction, image segmentation, classification, and regression through a natural language interface, requiring no coding from the user. Built on a modular architecture, mAIstro supports both open- and closed-source LLMs, and was evaluated using a large and diverse set of prompts across 16 open-source datasets, covering a wide range of imaging modalities, anatomical regions, and data types. The agents successfully executed all tasks, producing interpretable outputs and validated models. This work presents the first agentic framework capable of unifying data analysis, AI model development, and inference across varied healthcare applications, offering a reproducible and extensible foundation for clinical and research AI integration. The code is available at: https://github.com/eltzanis/mAIstro

Although deep learning approaches have stood out in recent years due to their state-of-the-art results, they continue to suffer from catastrophic forgetting, a dramatic decrease in overall performance when training with new classes added incrementally. This is due to current neural network architectures requiring the entire dataset, consisting of all the samples from the old as well as the new classes, to update the model -a requirement that becomes easily unsustainable as the number of classes grows. We address this issue with our approach to learn deep neural networks incrementally, using new data and only a small exemplar set corresponding to samples from the old classes. This is based on a loss composed of a distillation measure to retain the knowledge acquired from the old classes, and a cross-entropy loss to learn the new classes. Our incremental training is achieved while keeping the entire framework end-to-end, i.e., learning the data representation and the classifier jointly, unlike recent methods with no such guarantees. We evaluate our method extensively on the CIFAR-100 and ImageNet (ILSVRC 2012) image classification datasets, and show state-of-the-art performance.

Attempts to render deep learning models interpretable, data-efficient, and robust have seen some success through hybridisation with rule-based systems, for example, in Neural Theorem Provers (NTPs). These neuro-symbolic models can induce interpretable rules and learn representations from data via back-propagation, while providing logical explanations for their predictions. However, they are restricted by their computational complexity, as they need to consider all possible proof paths for explaining a goal, thus rendering them unfit for large-scale applications. We present Conditional Theorem Provers (CTPs), an extension to NTPs that learns an optimal rule selection strategy via gradient-based optimisation. We show that CTPs are scalable and yield state-of-the-art results on the CLUTRR dataset, which tests systematic generalisation of neural models by learning to reason over smaller graphs and evaluating on larger ones. Finally, CTPs show better link prediction results on standard benchmarks in comparison with other neural-symbolic models, while being explainable. All source code and datasets are available online, at https://github.com/uclnlp/ctp.

The lack of data tends to limit the outcomes of deep learning research, particularly when dealing with end-to-end learning stacks processing raw data such as waveforms. In this study, 1.2M tracks annotated with musical labels are available to train our end-to-end models. This large amount of data allows us to unrestrictedly explore two different design paradigms for music auto-tagging: assumption-free models - using waveforms as input with very small convolutional filters; and models that rely on domain knowledge - log-mel spectrograms with a convolutional neural network designed to learn timbral and temporal features. Our work focuses on studying how these two types of deep architectures perform when datasets of variable size are available for training: the MagnaTagATune (25k songs), the Million Song Dataset (240k songs), and a private dataset of 1.2M songs. Our experiments suggest that music domain assumptions are relevant when not enough training data are available, thus showing how waveform-based models outperform spectrogram-based ones in large-scale data scenarios.

The success of deep learning is frequently described as the ability to train all parameters of a network on a specific application in an end-to-end fashion. Yet, several design choices on the camera level, including the pixel layout of the sensor, are considered as pre-defined and fixed, and high resolution, regular pixel layouts are considered to be the most generic ones in computer vision and graphics, treating all regions of an image as equally important. While several works have considered non-uniform, \eg, hexagonal or foveated, pixel layouts in hardware and image processing, the layout has not been integrated into the end-to-end learning paradigm so far. In this work, we present the first truly end-to-end trained imaging pipeline that optimizes the size and distribution of pixels on the imaging sensor jointly with the parameters of a given neural network on a specific task. We derive an analytic, differentiable approach for the sensor layout parameterization that allows for task-specific, local varying pixel resolutions. We present two pixel layout parameterization functions: rectangular and curvilinear grid shapes that retain a regular topology. We provide a drop-in module that approximates sensor simulation given existing high-resolution images to directly connect our method with existing deep learning models. We show that network predictions benefit from learnable pixel layouts for two different downstream tasks, classification and semantic segmentation.

Recently slot filling has witnessed great development thanks to deep learning and the availability of large-scale annotated data. However, it poses a critical challenge to handle a novel domain whose samples are never seen during training. The recognition performance might be greatly degraded due to severe domain shifts. Most prior works deal with this problem in a two-pass pipeline manner based on metric learning. In practice, these dominant pipeline models may be limited in computational efficiency and generalization capacity because of non-parallel inference and context-free discrete label embeddings. To this end, we re-examine the typical metric-based methods, and propose a new adaptive end-to-end metric learning scheme for the challenging zero-shot slot filling. Considering simplicity, efficiency and generalizability, we present a cascade-style joint learning framework coupled with context-aware soft label representations and slot-level contrastive representation learning to mitigate the data and label shift problems effectively. Extensive experiments on public benchmarks demonstrate the superiority of the proposed approach over a series of competitive baselines.

Time series classification (TSC) is dominated by a two-stage paradigm: train a feature encoder -- either from scratch on the target dataset or via pretraining on large corpora -- and then fit a task-specific classifier on top. While effective, this decoupling optimizes representation learning independently of the classification objective, requires per-dataset training, and prevents the model from exploiting label information during inference. We introduce TimEE, a 4.5M-parameter foundation model for end-to-end TSC via in-context learning. Given a labeled support set and a query time series, TimEE directly outputs a predicted class distribution in a single forward pass with no per-dataset training required. Following the prior-data fitted network (PFN) framework, TimEE is meta-trained exclusively on synthetic TSC tasks, where each task contains time series with distinct class identities arising from structured distributional shifts in the generative process. Despite seeing no real time series during pre-training, TimEE ranks first in ROC AUC (and third on accuracy) on the UCR benchmark among all compared methods, which include both foundation models and supervised deep learning baselines. To our knowledge, TimEE is the first purely synthetic-pretrained model to reach state-of-the-art performance on the UCR benchmark. These results establish end-to-end ICL with synthetic priors as a compelling, largely unexplored direction for TSC, with scaling, prior design, and richer generation mechanisms as natural avenues for improvement. Code is publicly available at http://github.com/automl/timee.

Learning continually from non-stationary data streams is a long-standing goal and a challenging problem in machine learning. Recently, we have witnessed a renewed and fast-growing interest in continual learning, especially within the deep learning community. However, algorithmic solutions are often difficult to re-implement, evaluate and port across different settings, where even results on standard benchmarks are hard to reproduce. In this work, we propose Avalanche, an open-source end-to-end library for continual learning research based on PyTorch. Avalanche is designed to provide a shared and collaborative codebase for fast prototyping, training, and reproducible evaluation of continual learning algorithms.

Deep learning techniques have provided significant improvements in hyperspectral image (HSI) classification. The current deep learning based HSI classifiers follow a patch-based learning framework by dividing the image into overlapping patches. As such, these methods are local learning methods, which have a high computational cost. In this paper, a fast patch-free global learning (FPGA) framework is proposed for HSI classification. In FPGA, an encoder-decoder based FCN is utilized to consider the global spatial information by processing the whole image, which results in fast inference. However, it is difficult to directly utilize the encoder-decoder based FCN for HSI classification as it always fails to converge due to the insufficiently diverse gradients caused by the limited training samples. To solve the divergence problem and maintain the abilities of FCN of fast inference and global spatial information mining, a global stochastic stratified sampling strategy is first proposed by transforming all the training samples into a stochastic sequence of stratified samples. This strategy can obtain diverse gradients to guarantee the convergence of the FCN in the FPGA framework. For a better design of FCN architecture, FreeNet, which is a fully end-to-end network for HSI classification, is proposed to maximize the exploitation of the global spatial information and boost the performance via a spectral attention based encoder and a lightweight decoder. A lateral connection module is also designed to connect the encoder and decoder, fusing the spatial details in the encoder and the semantic features in the decoder. The experimental results obtained using three public benchmark datasets suggest that the FPGA framework is superior to the patch-based framework in both speed and accuracy for HSI classification. Code has been made available at: https://github.com/Z-Zheng/FreeNet.

Deep learning (DL) has proven to be a highly effective approach for developing models in diverse contexts, including visual perception, speech recognition, and machine translation. However, the end-to-end process for applying DL is not trivial. It requires grappling with problem formulation and context understanding, data engineering, model development, deployment, continuous monitoring and maintenance, and so on. Moreover, each of these steps typically relies heavily on humans, in terms of both knowledge and interactions, which impedes the further advancement and democratization of DL. Consequently, in response to these issues, a new field has emerged over the last few years: automated deep learning (AutoDL). This endeavor seeks to minimize the need for human involvement and is best known for its achievements in neural architecture search (NAS), a topic that has been the focus of several surveys. That stated, NAS is not the be-all and end-all of AutoDL. Accordingly, this review adopts an overarching perspective, examining research efforts into automation across the entirety of an archetypal DL workflow. In so doing, this work also proposes a comprehensive set of ten criteria by which to assess existing work in both individual publications and broader research areas. These criteria are: novelty, solution quality, efficiency, stability, interpretability, reproducibility, engineering quality, scalability, generalizability, and eco-friendliness. Thus, ultimately, this review provides an evaluative overview of AutoDL in the early 2020s, identifying where future opportunities for progress may exist.

The current dominant paradigm in sensorimotor control, whether imitation or reinforcement learning, is to train policies directly in raw action spaces such as torque, joint angle, or end-effector position. This forces the agent to make decisions individually at each timestep in training, and hence, limits the scalability to continuous, high-dimensional, and long-horizon tasks. In contrast, research in classical robotics has, for a long time, exploited dynamical systems as a policy representation to learn robot behaviors via demonstrations. These techniques, however, lack the flexibility and generalizability provided by deep learning or reinforcement learning and have remained under-explored in such settings. In this work, we begin to close this gap and embed the structure of a dynamical system into deep neural network-based policies by reparameterizing action spaces via second-order differential equations. We propose Neural Dynamic Policies (NDPs) that make predictions in trajectory distribution space as opposed to prior policy learning methods where actions represent the raw control space. The embedded structure allows end-to-end policy learning for both reinforcement and imitation learning setups. We show that NDPs outperform the prior state-of-the-art in terms of either efficiency or performance across several robotic control tasks for both imitation and reinforcement learning setups. Project video and code are available at https://shikharbahl.github.io/neural-dynamic-policies/

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests that the use of multi-modal data and advanced modeling methods, such as the ones based on Deep Learning, has promise in tackling this challenge. To date, however, the evidence on the efficacy of this approach is limited. In this study, we leveraged recent advances in Deep Learning and, using a Transformer approach, developed a unified framework for the multi-modal fusion of knee imaging data. Subsequently, we analyzed its performance across a range of scenarios by investigating multiple progression horizons -- from short-term to long-term. We report our findings using a large cohort (n=2421-3967) derived from the Osteoarthritis Initiative dataset. We show that structural knee MRI allows identifying radiographic KOA progressors on par with multi-modal fusion approaches, achieving an area under the ROC curve (ROC AUC) of 0.70-0.76 and Average Precision (AP) of 0.15-0.54 in 2-8 year horizons. Progression within 1 year was better predicted with a multi-modal method using X-ray, structural, and compositional MR images -- ROC AUC of 0.76(0.04), AP of 0.13(0.04) -- or via clinical data. Our follow-up analysis generally shows that prediction from the imaging data is more accurate for post-traumatic subjects, and we further investigate which subject subgroups may benefit the most. The present study provides novel insights into multi-modal imaging of KOA and brings a unified data-driven framework for studying its progression in an end-to-end manner, providing new tools for the design of more efficient clinical trials. The source code of our framework and the pre-trained models are made publicly available.

Focusing on the task of point-to-point navigation for an autonomous driving vehicle, we propose a novel deep learning model trained with end-to-end and multi-task learning manners to perform both perception and control tasks simultaneously. The model is used to drive the ego vehicle safely by following a sequence of routes defined by the global planner. The perception part of the model is used to encode high-dimensional observation data provided by an RGBD camera while performing semantic segmentation, semantic depth cloud (SDC) mapping, and traffic light state and stop sign prediction. Then, the control part decodes the encoded features along with additional information provided by GPS and speedometer to predict waypoints that come with a latent feature space. Furthermore, two agents are employed to process these outputs and make a control policy that determines the level of steering, throttle, and brake as the final action. The model is evaluated on CARLA simulator with various scenarios made of normal-adversarial situations and different weathers to mimic real-world conditions. In addition, we do a comparative study with some recent models to justify the performance in multiple aspects of driving. Moreover, we also conduct an ablation study on SDC mapping and multi-agent to understand their roles and behavior. As a result, our model achieves the highest driving score even with fewer parameters and computation load. To support future studies, we share our codes at https://github.com/oskarnatan/end-to-end-driving.

Through evolution, nature has presented a set of remarkable protein materials, including elastins, silks, keratins and collagens with superior mechanical performances that play crucial roles in mechanobiology. However, going beyond natural designs to discover proteins that meet specified mechanical properties remains challenging. Here we report a generative model that predicts protein designs to meet complex nonlinear mechanical property-design objectives. Our model leverages deep knowledge on protein sequences from a pre-trained protein language model and maps mechanical unfolding responses to create novel proteins. Via full-atom molecular simulations for direct validation, we demonstrate that the designed proteins are novel, and fulfill the targeted mechanical properties, including unfolding energy and mechanical strength, as well as the detailed unfolding force-separation curves. Our model offers rapid pathways to explore the enormous mechanobiological protein sequence space unconstrained by biological synthesis, using mechanical features as target to enable the discovery of protein materials with superior mechanical properties.

Modern cars are incorporating an increasing number of driver assist features, among which automatic lane keeping. The latter allows the car to properly position itself within the road lanes, which is also crucial for any subsequent lane departure or trajectory planning decision in fully autonomous cars. Traditional lane detection methods rely on a combination of highly-specialized, hand-crafted features and heuristics, usually followed by post-processing techniques, that are computationally expensive and prone to scalability due to road scene variations. More recent approaches leverage deep learning models, trained for pixel-wise lane segmentation, even when no markings are present in the image due to their big receptive field. Despite their advantages, these methods are limited to detecting a pre-defined, fixed number of lanes, e.g. ego-lanes, and can not cope with lane changes. In this paper, we go beyond the aforementioned limitations and propose to cast the lane detection problem as an instance segmentation problem - in which each lane forms its own instance - that can be trained end-to-end. To parametrize the segmented lane instances before fitting the lane, we further propose to apply a learned perspective transformation, conditioned on the image, in contrast to a fixed "bird's-eye view" transformation. By doing so, we ensure a lane fitting which is robust against road plane changes, unlike existing approaches that rely on a fixed, pre-defined transformation. In summary, we propose a fast lane detection algorithm, running at 50 fps, which can handle a variable number of lanes and cope with lane changes. We verify our method on the tuSimple dataset and achieve competitive results.

Background: Accelerating dynamic MRI is vital for advancing clinical applications and improving patient comfort. Commonly, deep learning (DL) methods for accelerated dynamic MRI reconstruction typically rely on uniformly applying non-adaptive predetermined or random subsampling patterns across all temporal frames of the dynamic acquisition. This approach fails to exploit temporal correlations or optimize subsampling on a case-by-case basis. Purpose: To develop an end-to-end approach for adaptive dynamic MRI subsampling and reconstruction, capable of generating customized sampling patterns maximizing at the same time reconstruction quality. Methods: We introduce the End-to-end Adaptive Dynamic Sampling and Reconstruction (E2E-ADS-Recon) for MRI framework, which integrates an adaptive dynamic sampler (ADS) that adapts the acquisition trajectory to each case for a given acceleration factor with a state-of-the-art dynamic reconstruction network, vSHARP, for reconstructing the adaptively sampled data into a dynamic image. The ADS can produce either frame-specific patterns or unified patterns applied to all temporal frames. E2E-ADS-Recon is evaluated under both frame-specific and unified 1D or 2D sampling settings, using dynamic cine cardiac MRI data and compared with vSHARP models employing standard subsampling trajectories, as well as pipelines where ADS was replaced by parameterized samplers optimized for dataset-specific schemes. Results: E2E-ADS-Recon exhibited superior reconstruction quality, especially at high accelerations, in terms of standard quantitative metrics (SSIM, pSNR, NMSE). Conclusion: The proposed framework improves reconstruction quality, highlighting the importance of case-specific subsampling optimization in dynamic MRI applications.

Semantic segmentation and change detection are two fundamental challenges in remote sensing, requiring models to capture either spatial semantics or temporal differences from satellite imagery. Existing deep learning models often struggle with temporal inconsistencies or in capturing fine-grained spatial structures, require extensive pretraining, and offer limited interpretability - especially in real-world remote sensing scenarios. Recent advances in diffusion models show that Gaussian noise can be systematically leveraged to learn expressive data representations through denoising. Motivated by this, we investigate whether the noise process in diffusion models can be effectively utilized for discriminative tasks. We propose Noise2Map, a unified diffusion-based framework that repurposes the denoising process for fast, end-to-end discriminative learning. Unlike prior work that uses diffusion only for generation or feature extraction, Noise2Map directly predicts semantic or change maps using task-specific noise schedules and timestep conditioning, avoiding the costly sampling procedures of traditional diffusion models. The model is pretrained via self-supervised denoising and fine-tuned with supervision, enabling both interpretability and robustness. Our architecture supports both tasks (SS and CD) through a shared backbone and task-specific noise schedulers. Extensive evaluations on the SpaceNet7, WHU, and xView2 buildings damaged by wildfires datasets demonstrate that Noise2Map ranks on average 1st among seven models on semantic segmentation and 1st on change detection by a cross-dataset rank metric (average F1 primary, IoU tie-break). Ablation studies highlight the robustness of our model against different training noise schedulers and timestep control in the diffusion process, as well as the ability of the model to perform multi-task learning.

Speech-to-text (S2T) summarization is a time-saving technique for filtering and keeping up with the broadcast news uploaded online on a daily basis. The rise of large language models from deep learning with impressive text generation capabilities has placed the research focus on summarization systems that produce paraphrased compact versions of the document content, also known as abstractive summaries. End-to-end (E2E) modelling of S2T abstractive summarization is a promising approach that offers the possibility of generating rich latent representations that leverage non-verbal and acoustic information, as opposed to the use of only linguistic information from automatically generated transcripts in cascade systems. However, the few literature on E2E modelling of this task fails on exploring different domains, namely broadcast news, which is challenging domain where large and diversified volumes of data are presented to the user every day. We model S2T summarization both with a cascade and an E2E system for a corpus of broadcast news in French. Our novel E2E model leverages external data by resorting to transfer learning from a pre-trained T2T summarizer. Experiments show that both our cascade and E2E abstractive summarizers are stronger than an extractive baseline. However, the performance of the E2E model still lies behind the cascade one, which is object of an extensive analysis that includes future directions to close that gap.

An automatic table recognition method for interpretation of tabular data in document images majorly involves solving two problems of table detection and table structure recognition. The prior work involved solving both problems independently using two separate approaches. More recent works signify the use of deep learning-based solutions while also attempting to design an end to end solution. In this paper, we present an improved deep learning-based end to end approach for solving both problems of table detection and structure recognition using a single Convolution Neural Network (CNN) model. We propose CascadeTabNet: a Cascade mask Region-based CNN High-Resolution Network (Cascade mask R-CNN HRNet) based model that detects the regions of tables and recognizes the structural body cells from the detected tables at the same time. We evaluate our results on ICDAR 2013, ICDAR 2019 and TableBank public datasets. We achieved 3rd rank in ICDAR 2019 post-competition results for table detection while attaining the best accuracy results for the ICDAR 2013 and TableBank dataset. We also attain the highest accuracy results on the ICDAR 2019 table structure recognition dataset. Additionally, we demonstrate effective transfer learning and image augmentation techniques that enable CNNs to achieve very accurate table detection results. Code and dataset has been made available at: https://github.com/DevashishPrasad/CascadeTabNet

Although deep learning and end-to-end models have been widely used and shown superiority in automatic speech recognition (ASR) and text-to-speech (TTS) synthesis, state-of-the-art forced alignment (FA) models are still based on hidden Markov model (HMM). HMM has limited view of contextual information and is developed with long pipelines, leading to error accumulation and unsatisfactory performance. Inspired by the capability of attention mechanism in capturing long term contextual information and learning alignments in ASR and TTS, we propose a neural network based end-to-end forced aligner called NeuFA, in which a novel bidirectional attention mechanism plays an essential role. NeuFA integrates the alignment learning of both ASR and TTS tasks in a unified framework by learning bidirectional alignment information from a shared attention matrix in the proposed bidirectional attention mechanism. Alignments are extracted from the learnt attention weights and optimized by the ASR, TTS and FA tasks in a multi-task learning manner. Experimental results demonstrate the effectiveness of our proposed model, with mean absolute error on test set drops from 25.8 ms to 23.7 ms at word level, and from 17.0 ms to 15.7 ms at phoneme level compared with state-of-the-art HMM based model.

The majority of recent progress in Optical Music Recognition (OMR) has been achieved with Deep Learning methods, especially models following the end-to-end paradigm, reading input images and producing a linear sequence of tokens. Unfortunately, many music scores, especially piano music, cannot be easily converted to a linear sequence. This has led OMR researchers to use custom linearized encodings, instead of broadly accepted structured formats for music notation. Their diversity makes it difficult to compare the performance of OMR systems directly. To bring recent OMR model progress closer to useful results: (a) We define a sequential format called Linearized MusicXML, allowing to train an end-to-end model directly and maintaining close cohesion and compatibility with the industry-standard MusicXML format. (b) We create a dev and test set for benchmarking typeset OMR with MusicXML ground truth based on the OpenScore Lieder corpus. They contain 1,438 and 1,493 pianoform systems, each with an image from IMSLP. (c) We train and fine-tune an end-to-end model to serve as a baseline on the dataset and employ the TEDn metric to evaluate the model. We also test our model against the recently published synthetic pianoform dataset GrandStaff and surpass the state-of-the-art results.

For analysing and/or understanding languages having no word boundaries based on morphological analysis such as Japanese, Chinese, and Thai, it is desirable to perform appropriate word segmentation before word embeddings. But it is inherently difficult in these languages. In recent years, various language models based on deep learning have made remarkable progress, and some of these methodologies utilizing character-level features have successfully avoided such a difficult problem. However, when a model is fed character-level features of the above languages, it often causes overfitting due to a large number of character types. In this paper, we propose a CE-CLCNN, character-level convolutional neural networks using a character encoder to tackle these problems. The proposed CE-CLCNN is an end-to-end learning model and has an image-based character encoder, i.e. the CE-CLCNN handles each character in the target document as an image. Through various experiments, we found and confirmed that our CE-CLCNN captured closely embedded features for visually and semantically similar characters and achieves state-of-the-art results on several open document classification tasks. In this paper we report the performance of our CE-CLCNN with the Wikipedia title estimation task and analyse the internal behaviour.

Thanks to improvements in machine learning techniques including deep learning, a free large-scale speech corpus that can be shared between academic institutions and commercial companies has an important role. However, such a corpus for Japanese speech synthesis does not exist. In this paper, we designed a novel Japanese speech corpus, named the "JSUT corpus," that is aimed at achieving end-to-end speech synthesis. The corpus consists of 10 hours of reading-style speech data and its transcription and covers all of the main pronunciations of daily-use Japanese characters. In this paper, we describe how we designed and analyzed the corpus. The corpus is freely available online.

Innovation in the physical layer of communication systems has traditionally been achieved by breaking down the transceivers into sets of processing blocks, each optimized independently based on mathematical models. Conversely, deep learning (DL)-based systems are able to handle increasingly complex tasks for which no tractable models are available. This thesis aims at comparing different approaches to unlock the full potential of DL in the physical layer. First, we describe a neural network (NN)-based block strategy, where an NN is optimized to replace a block in a communication system. We apply this strategy to introduce a multi-user multiple-input multiple-output (MU-MIMO) detector that builds on top of an existing DL-based architecture. Second, we detail an end-to-end strategy, in which the transmitter and receiver are modeled as an autoencoder. This approach is illustrated with the design of waveforms that achieve high throughputs while satisfying peak-to-average power ratio (PAPR) and adjacent channel leakage ratio (ACLR) constraints. Lastly, we propose a hybrid strategy, where multiple DL components are inserted into a traditional architecture but are trained to optimize the end-to-end performance. To demonstrate its benefits, we propose a DL-enhanced MU-MIMO receiver that both enable lower bit error rates (BERs) compared to a conventional receiver and remains scalable to any number of users. Each approach has its own strengths and shortcomings. While the first one is the easiest to implement, its individual block optimization does not ensure the overall system optimality. On the other hand, systems designed with the second approach are computationally complex but allow for new opportunities such as pilotless transmissions. Finally, the combined flexibility and end-to-end performance gains of the third approach motivate its use for short-term practical implementations.

The privacy concerns of providing deep learning inference as a service have underscored the need for private inference (PI) protocols that protect users' data and the service provider's model using cryptographic methods. Recently proposed PI protocols have achieved significant reductions in PI latency by moving the computationally heavy homomorphic encryption (HE) parts to an offline/pre-compute phase. Paired with recent optimizations that tailor networks for PI, these protocols have achieved performance levels that are tantalizingly close to being practical. In this paper, we conduct a rigorous end-to-end characterization of PI protocols and optimization techniques and find that the current understanding of PI performance is overly optimistic. Specifically, we find that offline storage costs of garbled circuits (GC), a key cryptographic protocol used in PI, on user/client devices are prohibitively high and force much of the expensive offline HE computation to the online phase, resulting in a 10-1000times increase to PI latency. We propose a modified PI protocol that significantly reduces client-side storage costs for a small increase in online latency. Evaluated end-to-end, the modified protocol outperforms current protocols by reducing the mean PI latency by 4times for ResNet18 on TinyImageNet. We conclude with a discussion of several recently proposed PI optimizations in light of the findings and note many actually increase PI latency when evaluated from an end-to-end perspective.

An important problem in ad-hoc microphone speech separation is how to guarantee the robustness of a system with respect to the locations and numbers of microphones. The former requires the system to be invariant to different indexing of the microphones with the same locations, while the latter requires the system to be able to process inputs with varying dimensions. Conventional optimization-based beamforming techniques satisfy these requirements by definition, while for deep learning-based end-to-end systems those constraints are not fully addressed. In this paper, we propose transform-average-concatenate (TAC), a simple design paradigm for channel permutation and number invariant multi-channel speech separation. Based on the filter-and-sum network (FaSNet), a recently proposed end-to-end time-domain beamforming system, we show how TAC significantly improves the separation performance across various numbers of microphones in noisy reverberant separation tasks with ad-hoc arrays. Moreover, we show that TAC also significantly improves the separation performance with fixed geometry array configuration, further proving the effectiveness of the proposed paradigm in the general problem of multi-microphone speech separation.

Financial AI holds great promise for transforming modern finance, with the potential to support a wide range of tasks such as market forecasting, portfolio management, quantitative trading, and automated analysis. However, existing platforms remain limited in task coverage, lack robust multimodal data integration, and offer insufficient support for the training and deployment of large language models (LLMs). In response to these limitations, we present FinWorld, an all-in-one open-source platform that provides end-to-end support for the entire financial AI workflow, from data acquisition to experimentation and deployment. FinWorld distinguishes itself through native integration of heterogeneous financial data, unified support for diverse AI paradigms, and advanced agent automation, enabling seamless development and deployment. Leveraging data from 2 representative markets, 4 stock pools, and over 800 million financial data points, we conduct comprehensive experiments on 4 key financial AI tasks. These experiments systematically evaluate deep learning and reinforcement learning algorithms, with particular emphasis on RL-based finetuning for LLMs and LLM Agents. The empirical results demonstrate that FinWorld significantly enhances reproducibility, supports transparent benchmarking, and streamlines deployment, thereby providing a strong foundation for future research and real-world applications. Code is available at Github~https://github.com/DVampire/FinWorld.

Clustering is a widely used unsupervised learning technique involving an intensive discrete optimization problem. Associative Memory models or AMs are differentiable neural networks defining a recursive dynamical system, which have been integrated with various deep learning architectures. We uncover a novel connection between the AM dynamics and the inherent discrete assignment necessary in clustering to propose a novel unconstrained continuous relaxation of the discrete clustering problem, enabling end-to-end differentiable clustering with AM, dubbed ClAM. Leveraging the pattern completion ability of AMs, we further develop a novel self-supervised clustering loss. Our evaluations on varied datasets demonstrate that ClAM benefits from the self-supervision, and significantly improves upon both the traditional Lloyd's k-means algorithm, and more recent continuous clustering relaxations (by upto 60% in terms of the Silhouette Coefficient).

The deep learning revolution, kicked off by AlexNet, taught us that end-to-end training beats decomposing a problem into hand-designed stages. Generative modeling, however, has remained the exception-despite generative models being remarkably capable, they are still not trained end-to-end. This is because, at its core, generative modeling is about handling distributions with many modes, and existing scalable approaches handle this the same way, by factoring the generation procedure, which prevents end-to-end generation. In this work, we introduce Explorative Modeling, a new paradigm that instead factors the training loop, exploring K candidate matches between model generations and data, and training on the best, so predictions commit to modes rather than blurring them. We find Explorative Models (XMs) useful in two settings. First, increasing exploration adds a third pretraining axis beyond parameters and data for existing generative models-where scaling exploration monotonically improves performance across both continuous and discrete domains (images, video, and language). Notably, gains from exploration increase with scale, climbing from 7% to 36% as data scales and from 13% to 23% as models grow, with efficiency gains more than doubling at 3x the compute. Concretely, exploration improves FLOP efficiency by 4.1x, sample efficiency by 6.2x, parameter efficiency by 47%, lifts the strongest of image-generation recipes to a near-state-of-the-art 1.43 FID on ImageNet without guidance, enables scaling how end-to-end existing models are, and unlocks scaling generalization. Second, XMs enable end-to-end reconstructive generative modeling, matching diffusion on control tasks with 16-256x fewer inference steps. Together, these results establish XMs as both a new pretraining axis for existing generative models and a standalone end-to-end generative modeling paradigm.

We show that both an LSTM and a unitary-evolution recurrent neural network (URN) can achieve encouraging accuracy on two types of syntactic patterns: context-free long distance agreement, and mildly context-sensitive cross serial dependencies. This work extends recent experiments on deeply nested context-free long distance dependencies, with similar results. URNs differ from LSTMs in that they avoid non-linear activation functions, and they apply matrix multiplication to word embeddings encoded as unitary matrices. This permits them to retain all information in the processing of an input string over arbitrary distances. It also causes them to satisfy strict compositionality. URNs constitute a significant advance in the search for explainable models in deep learning applied to NLP.

Traditionally, most data-to-text applications have been designed using a modular pipeline architecture, in which non-linguistic input data is converted into natural language through several intermediate transformations. In contrast, recent neural models for data-to-text generation have been proposed as end-to-end approaches, where the non-linguistic input is rendered in natural language with much less explicit intermediate representations in-between. This study introduces a systematic comparison between neural pipeline and end-to-end data-to-text approaches for the generation of text from RDF triples. Both architectures were implemented making use of state-of-the art deep learning methods as the encoder-decoder Gated-Recurrent Units (GRU) and Transformer. Automatic and human evaluations together with a qualitative analysis suggest that having explicit intermediate steps in the generation process results in better texts than the ones generated by end-to-end approaches. Moreover, the pipeline models generalize better to unseen inputs. Data and code are publicly available.

This paper introduces a new open source platform for end-to-end speech processing named ESPnet. ESPnet mainly focuses on end-to-end automatic speech recognition (ASR), and adopts widely-used dynamic neural network toolkits, Chainer and PyTorch, as a main deep learning engine. ESPnet also follows the Kaldi ASR toolkit style for data processing, feature extraction/format, and recipes to provide a complete setup for speech recognition and other speech processing experiments. This paper explains a major architecture of this software platform, several important functionalities, which differentiate ESPnet from other open source ASR toolkits, and experimental results with major ASR benchmarks.

Missions to small celestial bodies rely heavily on optical feature tracking for characterization of and relative navigation around the target body. While deep learning has led to great advancements in feature detection and description, training and validating data-driven models for space applications is challenging due to the limited availability of large-scale, annotated datasets. This paper introduces AstroVision, a large-scale dataset comprised of 115,970 densely annotated, real images of 16 different small bodies captured during past and ongoing missions. We leverage AstroVision to develop a set of standardized benchmarks and conduct an exhaustive evaluation of both handcrafted and data-driven feature detection and description methods. Next, we employ AstroVision for end-to-end training of a state-of-the-art, deep feature detection and description network and demonstrate improved performance on multiple benchmarks. The full benchmarking pipeline and the dataset will be made publicly available to facilitate the advancement of computer vision algorithms for space applications.

Modern AI technologies for drug discovery are distributed across heterogeneous platforms-including web applications, desktop environments, and code libraries-leading to fragmented workflows, inconsistent interfaces, and high integration overhead. We present an agentic end-to-end drug design framework that leverages a Large Language Model (LLM) in conjunction with the Model Context Protocol (MCP) to dynamically coordinate access to biochemical databases, modular toolchains, and task-specific AI models. The system integrates four state-of-the-art components: MaSIF (MaSIF-site and MaSIF-seed-search) for geometric deep learning-based identification of protein-protein interaction (PPI) sites, Rosetta for grafting protein fragments onto protein backbones to form mini proteins, ProteinMPNN for amino acid sequences redesign, and AlphaFold3 for near-experimental accuracy in complex structure prediction. Starting from a target structure, the framework supports de novo binder generation via surface analysis, scaffold grafting and pose construction, sequence optimization, and structure prediction. Additionally, by replacing rigid, script-based workflows with a protocol-driven, LLM-coordinated architecture, the framework improves reproducibility, reduces manual overhead, and ensures extensibility, portability, and auditability across the entire drug design process.

In this paper we tackle a fundamental question: "Can we train latent diffusion models together with the variational auto-encoder (VAE) tokenizer in an end-to-end manner?" Traditional deep-learning wisdom dictates that end-to-end training is often preferable when possible. However, for latent diffusion transformers, it is observed that end-to-end training both VAE and diffusion-model using standard diffusion-loss is ineffective, even causing a degradation in final performance. We show that while diffusion loss is ineffective, end-to-end training can be unlocked through the representation-alignment (REPA) loss -- allowing both VAE and diffusion model to be jointly tuned during the training process. Despite its simplicity, the proposed training recipe (REPA-E) shows remarkable performance; speeding up diffusion model training by over 17x and 45x over REPA and vanilla training recipes, respectively. Interestingly, we observe that end-to-end tuning with REPA-E also improves the VAE itself; leading to improved latent space structure and downstream generation performance. In terms of final performance, our approach sets a new state-of-the-art; achieving FID of 1.26 and 1.83 with and without classifier-free guidance on ImageNet 256 x 256. Code is available at https://end2end-diffusion.github.io.

Phenotyping is fundamental to rare disease diagnosis, but manual curation of structured phenotypes from clinical notes is labor-intensive and difficult to scale. Existing artificial intelligence approaches typically optimize individual components of phenotyping but do not operationalize the full clinical workflow of extracting features from clinical text, standardizing them to Human Phenotype Ontology (HPO) terms, and prioritizing diagnostically informative HPO terms. We developed RARE-PHENIX, an end-to-end AI framework for rare disease phenotyping that integrates large language model-based phenotype extraction, ontology-grounded standardization to HPO terms, and supervised ranking of diagnostically informative phenotypes. We trained RARE-PHENIX using data from 2,671 patients across 11 Undiagnosed Diseases Network clinical sites, and externally validated it on 16,357 real-world clinical notes from Vanderbilt University Medical Center. Using clinician-curated HPO terms as the gold standard, RARE-PHENIX consistently outperformed a state-of-the-art deep learning baseline (PhenoBERT) across ontology-based similarity and precision-recall-F1 metrics in end-to-end evaluation (i.e., ontology-based similarity of 0.70 vs. 0.58). Ablation analyses demonstrated performance improvements with the addition of each module in RARE-PHENIX (extraction, standardization, and prioritization), supporting the value of modeling the full clinical phenotyping workflow. By modeling phenotyping as a clinically aligned workflow rather than a single extraction task, RARE-PHENIX provides structured, ranked phenotypes that are more concordant with clinician curation and has the potential to support human-in-the-loop rare disease diagnosis in real-world settings.

Beat tracking in musical performance MIDI is a challenging and important task for notation-level music transcription and rhythmical analysis, yet existing methods primarily focus on audio-based approaches. This paper proposes an end-to-end transformer-based model for beat and downbeat tracking in performance MIDI, leveraging an encoder-decoder architecture for sequence-to-sequence translation of MIDI input to beat annotations. Our approach introduces novel data preprocessing techniques, including dynamic augmentation and optimized tokenization strategies, to improve accuracy and generalizability across different datasets. We conduct extensive experiments using the A-MAPS, ASAP, GuitarSet, and Leduc datasets, comparing our model against state-of-the-art hidden Markov models (HMMs) and deep learning-based beat tracking methods. The results demonstrate that our model outperforms existing symbolic music beat tracking approaches, achieving competitive F1-scores across various musical styles and instruments. Our findings highlight the potential of transformer architectures for symbolic beat tracking and suggest future integration with automatic music transcription systems for enhanced music analysis and score generation.

We present RelBench, a public benchmark for solving predictive tasks over relational databases with graph neural networks. RelBench provides databases and tasks spanning diverse domains and scales, and is intended to be a foundational infrastructure for future research. We use RelBench to conduct the first comprehensive study of Relational Deep Learning (RDL) (Fey et al., 2024), which combines graph neural network predictive models with (deep) tabular models that extract initial entity-level representations from raw tables. End-to-end learned RDL models fully exploit the predictive signal encoded in primary-foreign key links, marking a significant shift away from the dominant paradigm of manual feature engineering combined with tabular models. To thoroughly evaluate RDL against this prior gold-standard, we conduct an in-depth user study where an experienced data scientist manually engineers features for each task. In this study, RDL learns better models whilst reducing human work needed by more than an order of magnitude. This demonstrates the power of deep learning for solving predictive tasks over relational databases, opening up many new research opportunities enabled by RelBench.

Data-based and learning-based sound source localization (SSL) has shown promising results in challenging conditions, and is commonly set as a classification or a regression problem. Regression-based approaches have certain advantages over classification-based, such as continuous direction-of-arrival estimation of static and moving sources. However, multi-source scenarios require multiple regressors without a clear training strategy up-to-date, that does not rely on auxiliary information such as simultaneous sound classification. We investigate end-to-end training of such methods with a technique recently proposed for video object detectors, adapted to the SSL setting. A differentiable network is constructed that can be plugged to the output of the localizer to solve the optimal assignment between predictions and references, optimizing directly the popular CLEAR-MOT tracking metrics. Results indicate large improvements over directly optimizing mean squared errors, in terms of localization error, detection metrics, and tracking capabilities.

Automatic estimation of cardiac ultrasound image quality can be beneficial for guiding operators and ensuring the accuracy of clinical measurements. Previous work often fails to distinguish the view correctness of the echocardiogram from the image quality. Additionally, previous studies only provide a global image quality value, which limits their practical utility. In this work, we developed and compared three methods to estimate image quality: 1) classic pixel-based metrics like the generalized contrast-to-noise ratio (gCNR) on myocardial segments as region of interest and left ventricle lumen as background, obtained using a U-Net segmentation 2) local image coherence derived from a U-Net model that predicts coherence from B-Mode images 3) a deep convolutional network that predicts the quality of each region directly in an end-to-end fashion. We evaluate each method against manual regional image quality annotations by three experienced cardiologists. The results indicate poor performance of the gCNR metric, with Spearman correlation to the annotations of rho = 0.24. The end-to-end learning model obtains the best result, rho = 0.69, comparable to the inter-observer correlation, rho = 0.63. Finally, the coherence-based method, with rho = 0.58, outperformed the classical metrics and is more generic than the end-to-end approach.

Introduction: Sleep staging is an essential component in the diagnosis of sleep disorders and management of sleep health. It is traditionally measured in a clinical setting and requires a labor-intensive labeling process. We hypothesize that it is possible to perform robust 4-class sleep staging using the raw photoplethysmography (PPG) time series and modern advances in deep learning (DL). Methods: We used two publicly available sleep databases that included raw PPG recordings, totalling 2,374 patients and 23,055 hours. We developed SleepPPG-Net, a DL model for 4-class sleep staging from the raw PPG time series. SleepPPG-Net was trained end-to-end and consists of a residual convolutional network for automatic feature extraction and a temporal convolutional network to capture long-range contextual information. We benchmarked the performance of SleepPPG-Net against models based on the best-reported state-of-the-art (SOTA) algorithms. Results: When benchmarked on a held-out test set, SleepPPG-Net obtained a median Cohen's Kappa (κ) score of 0.75 against 0.69 for the best SOTA approach. SleepPPG-Net showed good generalization performance to an external database, obtaining a κ score of 0.74 after transfer learning. Perspective: Overall, SleepPPG-Net provides new SOTA performance. In addition, performance is high enough to open the path to the development of wearables that meet the requirements for usage in clinical applications such as the diagnosis and monitoring of obstructive sleep apnea.

Accurate prediction of biochemical recurrence (BCR) after radical prostatectomy is critical for guiding adjuvant treatment and surveillance decisions in prostate cancer. However, existing clinicopathological risk models reduce complex morphology to relatively coarse descriptors, leaving substantial prognostic information embedded in routine histopathology underexplored. We present a deep learning-based biomarker that predicts continuous, patient-specific risk of BCR directly from H&E-stained whole-slide prostatectomy specimens. Trained end-to-end on time-to-event outcomes and evaluated across four independent international cohorts, our model demonstrates robust generalization across institutions and patient populations. When integrated with the CAPRA-S clinical risk score, the deep learning risk score consistently improved discrimination for BCR, increasing concordance indices from 0.725-0.772 to 0.749-0.788 across cohorts. To support clinical interpretability, outcome-grounded analyses revealed subtle histomorphological patterns associated with recurrence risk that are not captured by conventional clinicopathological risk scores. This multicohort study demonstrates that deep learning applied to routine prostate histopathology can deliver reproducible and clinically generalizable biomarkers that augment postoperative risk stratification, with potential to support personalized management of prostate cancer in real-world clinical settings.

VIBETENSOR is an open-source research system software stack for deep learning, generated by LLM-powered coding agents under high-level human guidance. In this paper, "fully generated" refers to code provenance: implementation changes were produced and applied as agent-proposed diffs; validation relied on agent-run builds, tests, and differential checks, without per-change manual diff review. It implements a PyTorch-style eager tensor library with a C++20 core (CPU+CUDA), a torch-like Python overlay via nanobind, and an experimental Node.js/TypeScript interface. Unlike thin bindings, VIBETENSOR includes its own tensor/storage system, schema-lite dispatcher, reverse-mode autograd, CUDA runtime (streams/events/graphs), a stream-ordered caching allocator with diagnostics, and a stable C ABI for dynamically loaded operator plugins. We view this release as a milestone for AI-assisted software engineering: it shows coding agents can generate a coherent deep learning runtime spanning language bindings down to CUDA memory management, validated primarily by builds and tests. We describe the architecture, summarize the workflow used to produce and validate the system, and evaluate the artifact. We report repository scale and test-suite composition, and summarize reproducible microbenchmarks from an accompanying AI-generated kernel suite, including fused attention versus PyTorch SDPA/FlashAttention. We also report end-to-end training sanity checks on 3 small workloads (sequence reversal, ViT, miniGPT) on NVIDIA H100 (Hopper, SM90) and Blackwell-class GPUs; multi-GPU results are Blackwell-only and use an optional CUTLASS-based ring-allreduce plugin gated on CUDA 13+ and sm103a toolchain support. Finally, we discuss failure modes in generated system software, including a "Frankenstein" composition effect where locally correct subsystems interact to yield globally suboptimal performance.

Non-contact remote photoplethysmography (rPPG) technology enables heart rate measurement from facial videos. However, existing network models still face challenges in accu racy, robustness, and generalization capability under complex scenarios. This paper proposes an end-to-end rPPG extraction network that employs 3D convolutional neural networks to reconstruct accurate rPPG signals from raw facial videos. We introduce a differential frame fusion module that integrates differential frames with original frames, enabling frame-level representations to capture blood volume pulse (BVP) variations. Additionally, we incorporate Temporal Shift Module (TSM) with self-attention mechanisms, which effectively enhance rPPG features with minimal computational overhead. Furthermore, we propose a novel dynamic hybrid loss function that provides stronger supervision for the network, effectively mitigating over fitting. Comprehensive experiments were conducted on not only the PURE and UBFC-rPPG datasets but also the challenging MMPD dataset under complex scenarios, involving both intra dataset and cross-dataset evaluations, which demonstrate the superior robustness and generalization capability of our network. Specifically, after training on PURE, our model achieved a mean absolute error (MAE) of 7.58 on the MMPD test set, outperforming the state-of-the-art models.

Deep learning (DL) has recently emerged as a pivotal technology for enhancing magnetic resonance imaging (MRI), a critical tool in diagnostic radiology. This review paper provides a comprehensive overview of recent advances in DL for MRI reconstruction. It focuses on DL approaches and architectures designed to improve image quality, accelerate scans, and address data-related challenges. These include end-to-end neural networks, pre-trained networks, generative models, and self-supervised methods. The paper also discusses the role of DL in optimizing acquisition protocols, enhancing robustness against distribution shifts, and tackling subtle bias. Drawing on the extensive literature and practical insights, it outlines current successes, limitations, and future directions for leveraging DL in MRI reconstruction, while emphasizing the potential of DL to significantly impact clinical imaging practices.

In this paper, we present a new objective prediction model for synthetic speech naturalness. It can be used to evaluate Text-To-Speech or Voice Conversion systems and works language independently. The model is trained end-to-end and based on a CNN-LSTM network that previously showed to give good results for speech quality estimation. We trained and tested the model on 16 different datasets, such as from the Blizzard Challenge and the Voice Conversion Challenge. Further, we show that the reliability of deep learning-based naturalness prediction can be improved by transfer learning from speech quality prediction models that are trained on objective POLQA scores. The proposed model is made publicly available and can, for example, be used to evaluate different TTS system configurations.

Deep networks have recently enjoyed enormous success when applied to recognition and classification problems in computer vision, but their use in graphics problems has been limited. In this work, we present a novel deep architecture that performs new view synthesis directly from pixels, trained from a large number of posed image sets. In contrast to traditional approaches which consist of multiple complex stages of processing, each of which require careful tuning and can fail in unexpected ways, our system is trained end-to-end. The pixels from neighboring views of a scene are presented to the network which then directly produces the pixels of the unseen view. The benefits of our approach include generality (we only require posed image sets and can easily apply our method to different domains), and high quality results on traditionally difficult scenes. We believe this is due to the end-to-end nature of our system which is able to plausibly generate pixels according to color, depth, and texture priors learnt automatically from the training data. To verify our method we show that it can convincingly reproduce known test views from nearby imagery. Additionally we show images rendered from novel viewpoints. To our knowledge, our work is the first to apply deep learning to the problem of new view synthesis from sets of real-world, natural imagery.

Lower extremity computed tomography (CT) contains clinically relevant information for body composition analysis, sarcopenia assessment, and musculoskeletal disease monitoring, but extracting these measurements at scale requires accurate tissue segmentation and an automated quantification workflow. Existing public segmentation tools are not designed for comprehensive lower extremity CT analysis, particularly for clinically important inter/intramuscular adipose tissue, and most public methods only provide mask prediction rather than an end-to-end quantification system. To address this problem, we present LegSegNet, a deep learning system for lower extremity CT tissue segmentation and body composition quantification. Given an input CT scan, LegSegNet segments bone, skeletal muscle, subcutaneous adipose tissue, and inter/intramuscular adipose tissue. It then computes quantitative tissue measurements for downstream analysis. We developed the segmentation model using 1,302 manually annotated CT slices and evaluated it on 900 held-out test slices, with all annotations reviewed by radiologists. We benchmark LegSegNet against a broad set of 2D segmentation methods, including CNN-based models, transformer-based models, and finetuned foundation models, and further evaluate its generalization on an external public CT dataset. LegSegNet achieves the best overall segmentation performance, with an average Dice score of 89.31 on the held-out test set. To our knowledge, LegSegNet is the first publicly available end-to-end system for lower extremity CT tissue segmentation and quantification, providing a practical evaluation tool for future computer vision research in medical image analysis. The code and model weights are available at: https://github.com/mazurowski-lab/LegSegNet

Despite their widespread success, the application of deep neural networks to functional data remains scarce today. The infinite dimensionality of functional data means standard learning algorithms can be applied only after appropriate dimension reduction, typically achieved via basis expansions. Currently, these bases are chosen a priori without the information for the task at hand and thus may not be effective for the designated task. We instead propose to adaptively learn these bases in an end-to-end fashion. We introduce neural networks that employ a new Basis Layer whose hidden units are each basis functions themselves implemented as a micro neural network. Our architecture learns to apply parsimonious dimension reduction to functional inputs that focuses only on information relevant to the target rather than irrelevant variation in the input function. Across numerous classification/regression tasks with functional data, our method empirically outperforms other types of neural networks, and we prove that our approach is statistically consistent with low generalization error. Code is available at: https://github.com/jwyyy/AdaFNN.

Chain-of-thought reasoning has driven striking advances in language model capability, yet every reasoning step grows the KV cache, creating a bottleneck to scaling this paradigm further. Current approaches manage these constraints on the model's behalf using hand-designed criteria. A more scalable approach would let end-to-end learning subsume this design choice entirely, following a broader pattern in deep learning. After all, if a model can learn to reason, why can't it learn to forget? We introduce Neural Garbage Collection (NGC), in which a language model learns to forget while learning to reason, trained end-to-end from outcome-based task reward alone. As the model reasons, it periodically pauses, decides which KV cache entries to evict, and continues to reason conditioned on the remaining cache. By treating tokens in a chain-of-thought and cache-eviction decisions as discrete actions sampled from the language model, we can use reinforcement learning to jointly optimize how the model reasons and how it manages its own memory: what the model evicts shapes what it remembers, what it remembers shapes its reasoning, and the correctness of that reasoning determines its reward. Crucially, the model learns this behavior entirely from a single learning signal - the outcome-based task reward - without supervised fine-tuning or proxy objectives. On Countdown, AMC, and AIME tasks, NGC maintains strong accuracy relative to the full-cache upper bound at 2-3x peak KV cache size compression and substantially outperforms eviction baselines. Our results are a first step towards a broader vision where end-to-end optimization drives both capability and efficiency in language models.

Solving complex classification tasks using deep neural networks typically requires large amounts of annotated data. However, corresponding class labels are noisy when provided by error-prone annotators, e.g., crowd workers. Training standard deep neural networks leads to subpar performances in such multi-annotator supervised learning settings. We address this issue by presenting a probabilistic training framework named multi-annotator deep learning (MaDL). A ground truth and an annotator performance model are jointly trained in an end-to-end learning approach. The ground truth model learns to predict instances' true class labels, while the annotator performance model infers probabilistic estimates of annotators' performances. A modular network architecture enables us to make varying assumptions regarding annotators' performances, e.g., an optional class or instance dependency. Further, we learn annotator embeddings to estimate annotators' densities within a latent space as proxies of their potentially correlated annotations. Together with a weighted loss function, we improve the learning from correlated annotation patterns. In a comprehensive evaluation, we examine three research questions about multi-annotator supervised learning. Our findings indicate MaDL's state-of-the-art performance and robustness against many correlated, spamming annotators.

Accurate air quality forecasts are vital for public health alerts, exposure assessment, and emissions control. In practice, observational data are often missing in varying proportions and patterns due to collection and transmission issues. These incomplete spatiotemporal records impede reliable inference and risk assessment and can lead to overconfident extrapolation. To address these challenges, we propose an end to end framework, the channel gated learning unit based spatiotemporal bayesian neural field (CGLUBNF). It uses Fourier features with a graph attention encoder to capture multiscale spatial dependencies and seasonal temporal dynamics. A channel gated learning unit, equipped with learnable activations and gated residual connections, adaptively filters and amplifies informative features. Bayesian inference jointly optimizes predictive distributions and parameter uncertainty, producing point estimates and calibrated prediction intervals. We conduct a systematic evaluation on two real world datasets, covering four typical missing data patterns and comparing against five state of the art baselines. CGLUBNF achieves superior prediction accuracy and sharper confidence intervals. In addition, we further validate robustness across multiple prediction horizons and analysis the contribution of extraneous variables. This research lays a foundation for reliable deep learning based spatio-temporal forecasting with incomplete observations in emerging sensing paradigms, such as real world vehicle borne mobile monitoring.

Relational Deep Learning (RDL) models multi-tabular databases as temporal heterogeneous graphs for end-to-end representation learning. While RDL is evolving rapidly, existing approaches face significant generalization obstacles. They are either schema-specific, requiring training from scratch for every new database, or they rely on monolithic architectures that entangle feature encoding with graph message-passing. Analyzing these limitations, we establish four core pillars for building foundational relational models: semantic granularity, structural topology, temporal causality, and unified optimization. Addressing these pillars, we propose a modular approach that decouples row encoding from graph message-passing. We introduce the Universal Row Encoder, a transformer-based module that integrates raw cell data with schema metadata-including column semantics, table names, and global distribution statistics-to produce table-width invariant row embeddings. By explicitly feeding global statistics to an intra-row self-attention mechanism, the encoder natively contextualizes unseen features and handles sparse data. Serving as a flexible "backend" for any downstream graph architecture, our pretrained encoder enhances cross-database knowledge transfer on the established RelBench benchmarks while improving learning convergence and memory footprint.

We propose Falcon, an end-to-end 3-party protocol for efficient private training and inference of large machine learning models. Falcon presents four main advantages - (i) It is highly expressive with support for high capacity networks such as VGG16 (ii) it supports batch normalization which is important for training complex networks such as AlexNet (iii) Falcon guarantees security with abort against malicious adversaries, assuming an honest majority (iv) Lastly, Falcon presents new theoretical insights for protocol design that make it highly efficient and allow it to outperform existing secure deep learning solutions. Compared to prior art for private inference, we are about 8x faster than SecureNN (PETS'19) on average and comparable to ABY3 (CCS'18). We are about 16-200x more communication efficient than either of these. For private training, we are about 6x faster than SecureNN, 4.4x faster than ABY3 and about 2-60x more communication efficient. Our experiments in the WAN setting show that over large networks and datasets, compute operations dominate the overall latency of MPC, as opposed to the communication.

Recent advances in singing voice synthesis (SVS) have attracted substantial attention from both academia and industry. With the advent of large language models and novel generative paradigms, producing controllable, high-fidelity singing voices has become an attainable goal. Yet the field still lacks a comprehensive survey that systematically analyzes deep-learning-based singing voice synthesis systems and their enabling technologies. To address the aforementioned issue, this survey first categorizes existing systems by task type and then organizes current architectures into two major paradigms: cascaded and end-to-end approaches. Moreover, we provide an in-depth analysis of core technologies, covering singing modeling and control techniques. Finally, we review relevant datasets, annotation tools, and evaluation benchmarks that support training and assessment. In appendix, we introduce training strategies and further discussion of SVS. This survey provides an up-to-date review of the literature on SVS models, which would be a useful reference for both researchers and engineers. Related materials are available at https://github.com/David-Pigeon/SyntheticSingers.

We propose a new class of deep reinforcement learning (RL) algorithms that model latent representations in hyperbolic space. Sequential decision-making requires reasoning about the possible future consequences of current behavior. Consequently, capturing the relationship between key evolving features for a given task is conducive to recovering effective policies. To this end, hyperbolic geometry provides deep RL models with a natural basis to precisely encode this inherently hierarchical information. However, applying existing methodologies from the hyperbolic deep learning literature leads to fatal optimization instabilities due to the non-stationarity and variance characterizing RL gradient estimators. Hence, we design a new general method that counteracts such optimization challenges and enables stable end-to-end learning with deep hyperbolic representations. We empirically validate our framework by applying it to popular on-policy and off-policy RL algorithms on the Procgen and Atari 100K benchmarks, attaining near universal performance and generalization benefits. Given its natural fit, we hope future RL research will consider hyperbolic representations as a standard tool.