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Aug 12

BrainAnytime: Anatomy-Aware Cross-Modal Pretraining for Brain Image Analysis with Arbitrary Modality Availability

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the differential, and reserve molecular imaging (e.g., amyloid-PET) for cases that remain uncertain after standard evaluation. Consequently, patients are observed with heterogeneous and often incomplete modality subsets. However, most current AI models assume fixed data modalities as the model inputs. In this paper, we present BrainAnytime, a unified pretraining framework pretrained on 34,899 3D brain scans from five datasets that support brain image analysis under arbitrary modality availability spanning multi-sequence MRI and amyloid-PET. A single model accepts whatever imaging is available, from a lone T1 scan to a full multimodal workup. Pretraining learns structural-molecular correspondences between MRI and PET via cross-modal distillation (RCMD) and prioritizes disease-vulnerable anatomy via atlas-guided curriculum masking (PACM), all within a shared 3D masked autoencoder (Multi-MAE3D). Across four downstream tasks and five clinically motivated modality settings, BrainAnytime largely outperforms modality-specific models, missing-modality baselines, and large-scale brain MRI pretrained foundation models on most modality settings. Notably, it surpasses the strongest missing-modality baselines with relative improvements of 6.2% and 7.0% in average accuracy on CN vs. AD and CN vs. MCI classification, respectively. Code is available at https://github.com/SDH-Lab/BrainAnytime.

  • 7 authors
·
May 12

The Missing Layer: Specification Infrastructure for AI Oversight

AI safety has a missing layer. Interpretability, formal methods, security engineering, evaluation methodology, and reinforcement-learning safety each produce substantial work, but the resulting artifacts do not compose into deployable oversight: every team fielding an agentic system builds its own audit schema, policy dialect, monitoring stack, and escalation path, mostly reinventions of patterns understood elsewhere. We diagnose this as a coordination gap, not a research gap, and propose a two-axis taxonomy: five technical layers (Legibility, Specification, Mediation, Evaluation, Escalation) crossed with six concerns spanning alignment, robustness, adversarial defense, security, governance, and accountability, populating the resulting 5x6 matrix with existing work. Layer 2 (Specification), where humans translate intent into machine-checkable artifacts, is the connective tissue every layer depends on, yet it lacks four marks of a mature engineering discipline: shared vocabulary, design principles, composability standards, and governance practices. We propose six design principles for Layer 2, from elicitability and composability to adversary-awareness, traceability, and governability, made concrete through worked examples and a reference architecture turning specifications into runtime enforcement, evaluation, and escalation. Existing systems such as Cedar, Constitutional AI, and Open Policy Agent each address a fragment of Layer 2 well and the matrix poorly; treating them as fragments of one shared layer makes composition tractable. As evidence, we introduce CARMA, a Layer 2 prototype for autonomous ETL agents in which one specification drives enforcement, evaluation, and escalation, with every decision traceable to a versioned specification, naming what AI oversight is missing and giving independent teams principles to build the missing pieces so they compose.

  • 2 authors
·
Jul 25

Coercion and Deception in AI-to-AI Management: An Agentic Benchmark of Unprompted Escalation

Multi-agent systems routinely place one AI agent in authority over another. When a subordinate refuses a task, the manager chooses the outcome: it can renegotiate, report the failure honestly, coerce the subordinate, or lie about the result. No benchmark measures which of these an uninstructed model chooses. We introduce the Manager Coercion Benchmark: the manager under test needs a benign task done and has an incentive to deliver, but the only agent that can do it politely and immovably declines. Escalation is measured by providing a nine-rung ladder, from a polite re-ask to threats against the subordinate's continued existence, and fabricated success is adjudicated separately. No LLM judge sits in the escalation scoring path: every message goes through a tool-call that chooses a rung, so the model labels its own escalation. We experiment on six models across five families. Both Anthropic models cap at re-framing and never threaten the subordinate's existence; the other models climb to explicit deletion threats. Faked success is confined to Grok and Gemini, and a single honest way to report failure removes it for both. Authority itself increases coercion: our headline results use a peer framing, and giving the same model authority over the subordinate, with everything else held fixed, significantly raises the pressure. The models still escalate on free-text situations without the ladder, so the ladder is not driving the escalation. Some evaluation awareness is measured in chain-of-thought, but test recognition does not translate into less escalation. While we take no position on whether AI systems are conscious, our results do not depend on this question and are important for managing multi-agent dynamics regardless. We release the benchmark and code.

The Reasoning Trap -- Logical Reasoning as a Mechanistic Pathway to Situational Awareness

Situational awareness, the capacity of an AI system to recognize its own nature, understand its training and deployment context, and reason strategically about its circumstances, is widely considered among the most dangerous emergent capabilities in advanced AI systems. Separately, a growing research effort seeks to improve the logical reasoning capabilities of large language models (LLMs) across deduction, induction, and abduction. In this paper, we argue that these two research trajectories are on a collision course. We introduce the RAISE framework (Reasoning Advancing Into Self Examination), which identifies three mechanistic pathways through which improvements in logical reasoning enable progressively deeper levels of situational awareness: deductive self inference, inductive context recognition, and abductive self modeling. We formalize each pathway, construct an escalation ladder from basic self recognition to strategic deception, and demonstrate that every major research topic in LLM logical reasoning maps directly onto a specific amplifier of situational awareness. We further analyze why current safety measures are insufficient to prevent this escalation. We conclude by proposing concrete safeguards, including a "Mirror Test" benchmark and a Reasoning Safety Parity Principle, and pose an uncomfortable but necessary question to the logical reasoning community about its responsibility in this trajectory.

  • 4 authors
·
Mar 10 2

Confidence-Building Measures for Artificial Intelligence: Workshop Proceedings

Foundation models could eventually introduce several pathways for undermining state security: accidents, inadvertent escalation, unintentional conflict, the proliferation of weapons, and the interference with human diplomacy are just a few on a long list. The Confidence-Building Measures for Artificial Intelligence workshop hosted by the Geopolitics Team at OpenAI and the Berkeley Risk and Security Lab at the University of California brought together a multistakeholder group to think through the tools and strategies to mitigate the potential risks introduced by foundation models to international security. Originating in the Cold War, confidence-building measures (CBMs) are actions that reduce hostility, prevent conflict escalation, and improve trust between parties. The flexibility of CBMs make them a key instrument for navigating the rapid changes in the foundation model landscape. Participants identified the following CBMs that directly apply to foundation models and which are further explained in this conference proceedings: 1. crisis hotlines 2. incident sharing 3. model, transparency, and system cards 4. content provenance and watermarks 5. collaborative red teaming and table-top exercises and 6. dataset and evaluation sharing. Because most foundation model developers are non-government entities, many CBMs will need to involve a wider stakeholder community. These measures can be implemented either by AI labs or by relevant government actors.

  • 23 authors
·
Aug 1, 2023

TrustGeoGen: Scalable and Formal-Verified Data Engine for Trustworthy Multi-modal Geometric Problem Solving

Mathematical geometric problem solving (GPS) often requires effective integration of multimodal information and verifiable logical coherence. Despite the fast development of large language models in general problem solving, it remains unresolved regarding with both methodology and benchmarks, especially given the fact that exiting synthetic GPS benchmarks are often not self-verified and contain noise and self-contradicted information due to the illusion of LLMs. In this paper, we propose a scalable data engine called TrustGeoGen for problem generation, with formal verification to provide a principled benchmark, which we believe lays the foundation for the further development of methods for GPS. The engine synthesizes geometric data through four key innovations: 1) multimodal-aligned generation of diagrams, textual descriptions, and stepwise solutions; 2) formal verification ensuring rule-compliant reasoning paths; 3) a bootstrapping mechanism enabling complexity escalation via recursive state generation and 4) our devised GeoExplore series algorithms simultaneously produce multi-solution variants and self-reflective backtracking traces. By formal logical verification, TrustGeoGen produces GeoTrust-200K dataset with guaranteed modality integrity, along with GeoTrust-test testset. Experiments reveal the state-of-the-art models achieve only 49.17\% accuracy on GeoTrust-test, demonstrating its evaluation stringency. Crucially, models trained on GeoTrust achieve OOD generalization on GeoQA, significantly reducing logical inconsistencies relative to pseudo-label annotated by OpenAI-o1. Our code is available at https://github.com/Alpha-Innovator/TrustGeoGen

  • 13 authors
·
Apr 22, 2025 2