Daily Papers

Instruction-based general video editing seeks to unify diverse editing operations within a single, intuitive interface. Existing approaches often rely on resource-intensive conditioning, using either heavyweight branches or costly source concatenation. Is there any efficient way to model editing intent? Thus, we introduce GRNEdit, a lightweight two-stage framework. GRN inspires our approach by encoding visual semantics through combinations of bits. Through task-specific fine-tuning, we take this representation further and recast editing semantics as local retain-or-flip decisions over individual bits. Source information is consequently modeled as coordinate-wise evidence supporting the observed binary states, while the GRN backbone remains responsible for resolving their global composition into coherent generative semantics. In Stage I, a compact encoder translates discrete source codes into continuous evidence signals, which GRN assimilates throughout binary refinement. Inspired by null-prompt training for classifier-free guidance, we further assign the null condition an editing-specific meaning: an empty instruction denotes no edit and is supervised through source reconstruction. This identity pathway not only implicitly strengthens evidence utilization and content preservation in Stage I, but also produces a source-preserving state in the same representation space as the edited state. Stage II can therefore directly compare each edited state with its source-preserving counterpart and use their discrepancy to revise unresolved target-bit decisions. Trained on only 0.6M pairs with less than 3\% conditioning parameters, GRNEdit-2B and GRNEdit-8B achieve scores of 4.03 and 4.18 on OpenVE-Bench. The 2B model outperforms multiple 14B open-source editors, while the 8B model performs on par with leading open-source editors.

With the growing popularity of personalized human content creation and sharing, there is a rising demand for advanced techniques in customized human image generation. However, current methods struggle to simultaneously maintain the fidelity of human identity and ensure the consistency of textual prompts, often resulting in suboptimal outcomes. This shortcoming is primarily due to the lack of effective constraints during the simultaneous integration of visual and textual prompts, leading to unhealthy mutual interference that compromises the full expression of both types of input. Building on prior research that suggests visual and textual conditions influence different regions of an image in distinct ways, we introduce a novel Dual-Pathway Adapter (DP-Adapter) to enhance both high-fidelity identity preservation and textual consistency in personalized human image generation. Our approach begins by decoupling the target human image into visually sensitive and text-sensitive regions. For visually sensitive regions, DP-Adapter employs an Identity-Enhancing Adapter (IEA) to preserve detailed identity features. For text-sensitive regions, we introduce a Textual-Consistency Adapter (TCA) to minimize visual interference and ensure the consistency of textual semantics. To seamlessly integrate these pathways, we develop a Fine-Grained Feature-Level Blending (FFB) module that efficiently combines hierarchical semantic features from both pathways, resulting in more natural and coherent synthesis outcomes. Additionally, DP-Adapter supports various innovative applications, including controllable headshot-to-full-body portrait generation, age editing, old-photo to reality, and expression editing.

We introduce ProtoPathway, an interpretable-by-design multimodal framework for cancer survival prediction that unifies whole slide imaging and transcriptomics through encoders producing biologically grounded representations on both sides of the fusion. On the histopathology side, K learnable morphological prototypes, trained end-to-end with the survival objective, serve as the slide representation itself: patches flow into prototype tokens via soft assignment, compressing variable-length patch sets into fixed task-adaptive tokens. On the genomic side, a bipartite graph neural network encodes gene expression within the Reactome pathway hierarchy, producing pathway embeddings that reflect both constituent genes and their broader biological context through bidirectional message passing over a shared gene--pathway graph. Cross-modal attention then operates over a compact prototype times pathway matrix in which prototypes query pathways, modeling the biological direction in which molecular programs give rise to tissue morphology. Because both axes carry stable task-learned identity, the attention matrix is itself an interpretability output, yielding native inference-time attribution across the full biological hierarchy, from genes through pathways and prototypes to spatial tissue maps. We evaluate on five TCGA cancer cohorts, demonstrating competitive or superior survival prediction with substantially improved biological interpretability and reduced computational cost, with interpretability claims validated through fold-stratified rank-based population-level analysis. Our source code, model weights, and Reactome pathways, together with a unified codebase reimplementing all multimodal survival baselines under identical preprocessing and evaluation, are available at: https://github.com/AmayaGS/ProtoPathway.

Photorealistic frontal view synthesis from a single face image has a wide range of applications in the field of face recognition. Although data-driven deep learning methods have been proposed to address this problem by seeking solutions from ample face data, this problem is still challenging because it is intrinsically ill-posed. This paper proposes a Two-Pathway Generative Adversarial Network (TP-GAN) for photorealistic frontal view synthesis by simultaneously perceiving global structures and local details. Four landmark located patch networks are proposed to attend to local textures in addition to the commonly used global encoder-decoder network. Except for the novel architecture, we make this ill-posed problem well constrained by introducing a combination of adversarial loss, symmetry loss and identity preserving loss. The combined loss function leverages both frontal face distribution and pre-trained discriminative deep face models to guide an identity preserving inference of frontal views from profiles. Different from previous deep learning methods that mainly rely on intermediate features for recognition, our method directly leverages the synthesized identity preserving image for downstream tasks like face recognition and attribution estimation. Experimental results demonstrate that our method not only presents compelling perceptual results but also outperforms state-of-the-art results on large pose face recognition.

Cell identity encompasses various semantic aspects of a cell, including cell type, pathway information, disease information, and more, which are essential for biologists to gain insights into its biological characteristics. Understanding cell identity from the transcriptomic data, such as annotating cell types, has become an important task in bioinformatics. As these semantic aspects are determined by human experts, it is impossible for AI models to effectively carry out cell identity understanding tasks without the supervision signals provided by single-cell and label pairs. The single-cell pre-trained language models (PLMs) currently used for this task are trained only on a single modality, transcriptomics data, lack an understanding of cell identity knowledge. As a result, they have to be fine-tuned for downstream tasks and struggle when lacking labeled data with the desired semantic labels. To address this issue, we propose an innovative solution by constructing a unified representation of single-cell data and natural language during the pre-training phase, allowing the model to directly incorporate insights related to cell identity. More specifically, we introduce LangCell, the first Language-Cell pre-training framework. LangCell utilizes texts enriched with cell identity information to gain a profound comprehension of cross-modal knowledge. Results from experiments conducted on different benchmarks show that LangCell is the only single-cell PLM that can work effectively in zero-shot cell identity understanding scenarios, and also significantly outperforms existing models in few-shot and fine-tuning cell identity understanding scenarios.

Makeup transfer aims to apply the makeup style from a reference face to a target face and has been increasingly adopted in practical applications. Existing GAN-based approaches typically rely on carefully designed loss functions to balance transfer quality and facial identity consistency, while diffusion-based methods often depend on additional face-control modules or algorithms to preserve identity. However, these auxiliary components tend to introduce extra errors, leading to suboptimal transfer results. To overcome these limitations, we propose FLUX-Makeup, a high-fidelity, identity-consistent, and robust makeup transfer framework that eliminates the need for any auxiliary face-control components. Instead, our method directly leverages source-reference image pairs to achieve superior transfer performance. Specifically, we build our framework upon FLUX-Kontext, using the source image as its native conditional input. Furthermore, we introduce RefLoRAInjector, a lightweight makeup feature injector that decouples the reference pathway from the backbone, enabling efficient and comprehensive extraction of makeup-related information. In parallel, we design a robust and scalable data generation pipeline to provide more accurate supervision during training. The paired makeup datasets produced by this pipeline significantly surpass the quality of all existing datasets. Extensive experiments demonstrate that FLUX-Makeup achieves state-of-the-art performance, exhibiting strong robustness across diverse scenarios.

Current learning-based subject customization approaches, predominantly relying on U-Net architectures, suffer from limited generalization ability and compromised image quality. Meanwhile, optimization-based methods require subject-specific fine-tuning, which inevitably degrades textual controllability. To address these challenges, we propose InstantCharacter, a scalable framework for character customization built upon a foundation diffusion transformer. InstantCharacter demonstrates three fundamental advantages: first, it achieves open-domain personalization across diverse character appearances, poses, and styles while maintaining high-fidelity results. Second, the framework introduces a scalable adapter with stacked transformer encoders, which effectively processes open-domain character features and seamlessly interacts with the latent space of modern diffusion transformers. Third, to effectively train the framework, we construct a large-scale character dataset containing 10-million-level samples. The dataset is systematically organized into paired (multi-view character) and unpaired (text-image combinations) subsets. This dual-data structure enables simultaneous optimization of identity consistency and textual editability through distinct learning pathways. Qualitative experiments demonstrate the advanced capabilities of InstantCharacter in generating high-fidelity, text-controllable, and character-consistent images, setting a new benchmark for character-driven image generation. Our source code is available at https://github.com/Tencent/InstantCharacter.

We present Lynx, a high-fidelity model for personalized video synthesis from a single input image. Built on an open-source Diffusion Transformer (DiT) foundation model, Lynx introduces two lightweight adapters to ensure identity fidelity. The ID-adapter employs a Perceiver Resampler to convert ArcFace-derived facial embeddings into compact identity tokens for conditioning, while the Ref-adapter integrates dense VAE features from a frozen reference pathway, injecting fine-grained details across all transformer layers through cross-attention. These modules collectively enable robust identity preservation while maintaining temporal coherence and visual realism. Through evaluation on a curated benchmark of 40 subjects and 20 unbiased prompts, which yielded 800 test cases, Lynx has demonstrated superior face resemblance, competitive prompt following, and strong video quality, thereby advancing the state of personalized video generation.

Recent advances have demonstrated compelling capabilities in synthesizing real individuals into generated videos, reflecting the growing demand for identity-aware content creation. Nevertheless, an openly accessible framework enabling fine-grained control over facial appearance and voice timbre across multiple identities remains unavailable. In this work, we present a unified and scalable framework for identity-aware joint audio-video generation, enabling high-fidelity and consistent personalization. Specifically, we introduce a data curation pipeline that automatically extracts identity-bearing information with paired annotations across audio and visual modalities, covering diverse scenarios from single-subject to multi-subject interactions. We further propose a flexible and scalable identity injection mechanism for single- and multi-subject scenarios, in which both facial appearance and vocal timbre act as identity-bearing control signals. Moreover, in light of modality disparity, we design a multi-stage training strategy to accelerate convergence and enforce cross-modal coherence. Experiments demonstrate the superiority of the proposed framework. For more details and qualitative results, please refer to our webpage: https://chen-yingjie.github.io/projects/Identity-as-Presence{Identity-as-Presence}.

Recent advances in generative modeling have enabled the generation of high-quality synthetic data that is applicable in a variety of domains, including face recognition. Here, state-of-the-art generative models typically rely on conditioning and fine-tuning of powerful pretrained diffusion models to facilitate the synthesis of realistic images of a desired identity. Yet, these models often do not consider the identity of subjects during training, leading to poor consistency between generated and intended identities. In contrast, methods that employ identity-based training objectives tend to overfit on various aspects of the identity, and in turn, lower the diversity of images that can be generated. To address these issues, we present in this paper a novel generative diffusion-based framework, called ID-Booth. ID-Booth consists of a denoising network responsible for data generation, a variational auto-encoder for mapping images to and from a lower-dimensional latent space and a text encoder that allows for prompt-based control over the generation procedure. The framework utilizes a novel triplet identity training objective and enables identity-consistent image generation while retaining the synthesis capabilities of pretrained diffusion models. Experiments with a state-of-the-art latent diffusion model and diverse prompts reveal that our method facilitates better intra-identity consistency and inter-identity separability than competing methods, while achieving higher image diversity. In turn, the produced data allows for effective augmentation of small-scale datasets and training of better-performing recognition models in a privacy-preserving manner. The source code for the ID-Booth framework is publicly available at https://github.com/dariant/ID-Booth.

Gene set analysis (GSA) is a foundational approach for interpreting genomic data of diseases by linking genes to biological processes. However, conventional GSA methods overlook clinical context of the analyses, often generating long lists of enriched pathways with redundant, nonspecific, or irrelevant results. Interpreting these requires extensive, ad-hoc manual effort, reducing both reliability and reproducibility. To address this limitation, we introduce cGSA, a novel AI-driven framework that enhances GSA by incorporating context-aware pathway prioritization. cGSA integrates gene cluster detection, enrichment analysis, and large language models to identify pathways that are not only statistically significant but also biologically meaningful. Benchmarking on 102 manually curated gene sets across 19 diseases and ten disease-related biological mechanisms shows that cGSA outperforms baseline methods by over 30%, with expert validation confirming its increased precision and interpretability. Two independent case studies in melanoma and breast cancer further demonstrate its potential to uncover context-specific insights and support targeted hypothesis generation.

We propose to improve transformers of a specific modality with irrelevant data from other modalities, e.g., improve an ImageNet model with audio or point cloud datasets. We would like to highlight that the data samples of the target modality are irrelevant to the other modalities, which distinguishes our method from other works utilizing paired (e.g., CLIP) or interleaved data of different modalities. We propose a methodology named Multimodal Pathway - given a target modality and a transformer designed for it, we use an auxiliary transformer trained with data of another modality and construct pathways to connect components of the two models so that data of the target modality can be processed by both models. In this way, we utilize the universal sequence-to-sequence modeling abilities of transformers obtained from two modalities. As a concrete implementation, we use a modality-specific tokenizer and task-specific head as usual but utilize the transformer blocks of the auxiliary model via a proposed method named Cross-Modal Re-parameterization, which exploits the auxiliary weights without any inference costs. On the image, point cloud, video, and audio recognition tasks, we observe significant and consistent performance improvements with irrelevant data from other modalities. The code and models are available at https://github.com/AILab-CVC/M2PT.

Existing methods for simulating individual identities often oversimplify human complexity, which may lead to incomplete or flattened representations. To address this, we introduce SPeCtrum, a grounded framework for constructing authentic LLM agent personas by incorporating an individual's multidimensional self-concept. SPeCtrum integrates three core components: Social Identity (S), Personal Identity (P), and Personal Life Context (C), each contributing distinct yet interconnected aspects of identity. To evaluate SPeCtrum's effectiveness in identity representation, we conducted automated and human evaluations. Automated evaluations using popular drama characters showed that Personal Life Context (C)-derived from short essays on preferences and daily routines-modeled characters' identities more effectively than Social Identity (S) and Personal Identity (P) alone and performed comparably to the full SPC combination. In contrast, human evaluations involving real-world individuals found that the full SPC combination provided a more comprehensive self-concept representation than C alone. Our findings suggest that while C alone may suffice for basic identity simulation, integrating S, P, and C enhances the authenticity and accuracy of real-world identity representation. Overall, SPeCtrum offers a structured approach for simulating individuals in LLM agents, enabling more personalized human-AI interactions and improving the realism of simulation-based behavioral studies.