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Nov 6

NPCBench: A Clinical Apprenticeship Benchmark for Multimodal Care-Pathway Reasoning in Nasopharyngeal Carcinoma

Current medical benchmarks typically break down clinical competence into isolated factual questions, single-image tasks, or static case vignettes. These tests score individual answers, but reveal less about whether a model can integrate subspecialty knowledge with multimodal evidence and track a patient's condition throughout a course of care. To close this gap, we introduce NPCBench, a clinical apprenticeship benchmark for nasopharyngeal carcinoma (NPC). NPCBench mirrors specialist training, from guideline and foundational knowledge to case planning, longitudinal review, CarePath integration, and open-ended consultation. It contains 4,777 component and consultation items and a 100-patient CarePath cohort with 417 scored diagnostic and care tasks. The episode-level evaluation tests whether diagnostic and care answers are jointly correct within a care pathway. By linking stepwise tasks to patient-level care trajectories, NPCBench evaluates whether models ground decisions in visual evidence, interpret changes in patient state, and meet clinical requirements in consultation. Across 30 evaluated models, we observe a composition gap: strong performance on individual tasks does not ensure jointly correct diagnostic and care answers for the same patient. Among 21 multimodal models, strict CarePath success reaches at most 23%. Paired controls and physician calibration further examine evidence grounding, longitudinal revision, and consultation judging. Overall, NPCBench broadens the evaluation of medical artificial intelligence beyond static question-answering paradigms to an apprenticeship-oriented assessment of clinical workflows, thereby offering a testbed for evidence-based and temporally coherent reasoning in oncology care.

InfiX-ai InfiX.ai
·
Nov 4 1

LSREP: A Longitudinal State-Replay Protocol for Evaluating Conversational Memory, with ICE v2 as an Audited Local-First Architecture

Conversational memory changes during use, so endpoint question answering alone cannot establish how a persistent state accumulates, ages, or incorporates revisions. We introduce LSREP, a Longitudinal State-Replay Evaluation Protocol combining ordered replay, explicit lifecycle schedules, repeated probes, evolving reference answers, and mechanism-fidelity checks. Its architectural case study is ICE v2, a local-first memory middleware with typed stores, retrieval fusion, and dynamic context budgets. The private, single-user instantiation contains 1,985 turns, 219 distinct probes, and 1,211 probe-checkpoint observations across 52 checkpoints. On three ordinary-density datasets, ICE v2 has a near-zero mean quality difference from vector-RAG while selecting 32% fewer fragments but using 6.6% more estimated prompt tokens. A fourth, dense dataset exposes catastrophic failures of the unbudgeted baseline. The fidelity audit limits attribution: procedural retrieval is defective, several mechanisms are unexercised, and graph utility is not established. In a complementary matched public diagnostic, ICE v2 loses decisively to pure vector-RAG on LongMemEval: 50.8% versus 72.8% in the evidence-only oracle and 43.0% versus 69.5% in full-S. Paired differences are -22.0 points (95% CI [-26.6, -17.4]) and -26.5 ([-31.3, -21.8]). Conservative abstention accompanies severe multi-session and temporal failures. ICE uses less context in this diagnostic, establishing a quality-cost trade-off rather than superior efficiency. Together, replay, fidelity auditing, and public endpoint testing expose distinct failure modes that neither architectural descriptions nor aggregate scores identify alone.

  • 1 authors
·
Sep 14

Standardizing Longitudinal Radiology Report Evaluation via Large Language Model Annotation

Longitudinal information in radiology reports refers to the sequential tracking of findings across multiple examinations over time, which is crucial for monitoring disease progression and guiding clinical decisions. Many recent automated radiology report generation methods are designed to capture longitudinal information; however, validating their performance is challenging. There is no proper tool to consistently label temporal changes in both ground-truth and model-generated texts for meaningful comparisons. Large language models (LLMs) offer a promising annotation alternative, as they are capable of capturing nuanced linguistic patterns and semantic similarities without extensive manual intervention. They also adapt well to new contexts. In this study, we therefore propose an LLM-based pipeline to automatically annotate longitudinal information in radiology reports. The pipeline first identifies sentences containing relevant information and then extracts the progression of diseases. We evaluate and compare five mainstream LLMs on these two tasks using 500 manually annotated reports. Considering both efficiency and performance, Qwen2.5-32B was subsequently selected and used to annotate another 95,169 reports from the public MIMIC-CXR dataset. Our Qwen2.5-32B-annotated dataset provided us with a standardized benchmark for evaluating report generation models. Using this new benchmark, we assessed seven state-of-the-art report generation models. Our LLM-based annotation method outperforms existing annotation solutions, achieving 11.3\% and 5.3\% higher F1-scores for longitudinal information detection and disease tracking, respectively. The source code is available at https://github.com/wxinyi1996/Standardizing-Longitudinal-Chest-X-ray-Report-Evaluation-via-Large-Language-Model-Annotation.git.

  • 4 authors
·
Aug 29

Measuring What the Crawler Sees: Discovery Curves, Core Persistence, and Shell Dynamics in Longitudinal Web Crawls

A longitudinal web crawl is a sequence of partial samples of an evolving URL population. Pairwise containment between two crawls is the standard probe; under a simple urn model of the crawl -- each round samples a fraction of the URLs and replaces a fraction -- it recovers two interpretable rates, per-round survival α and coverage c, but treats the population as uniform and consumes one pair at a time. In this work, we define a formal language for talking about a crawl. We extend this analysis with the discovery curve U(s, T), the cumulative URL footprint over a sliding window of T crawls starting at s, which under the same urn model is also a closed-form function of (α, c). Containment and the discovery curve are then two projections of one process: independent fits agree on (α, c) when the urn is homogeneous, so any disagreement is itself a measurement. Applied to Common Crawl (2020--2025, domain granularity) and to the German Academic Web (GAW, URL granularity), the two projections disagree on both archives, and a two-component urn with a persistent core fraction κ alongside shell parameters (α_partial, c_partial) reconciles the disagreement. A residual on c_partial remains, signaling that the shell itself is not homogeneous; κ is recorded as the scalar entry point to a rank-resolved generalization, which is left to follow-up work. web archive \and crawl coverage \and discovery curve \and urn model \and two-component model \and URL lifetime

  • 3 authors
·
Jul 14

RePrompT: Recurrent Prompt Tuning for Integrating Structured EHR Encoders with Large Language Models

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured EHRs (e.g., standardized diagnosis and medication codes) presents two key challenges. First, translating time-stamped EHR sequences into plain text can obscure both temporal structure and code identities, weakening the ability to capture code co-occurrence and longitudinal regularities. Second, unlike cohort-trained predictive models that learn a shared, task-aligned representation space across patients, LLMs are often applied in a case-isolated inference setting where each patient is processed independently without leveraging population-level patterns. To address these challenges, we introduce RePrompT, a time-aware LLM framework that integrates structured EHR encoders through prompt tuning, without modifying underlying architectures. Specifically, RePrompT recurrently incorporates latent states from prior visits to preserve longitudinal information, and injects population-level information through trainable prompt tokens derived from a cohort-trained, task-aligned EHR encoder. Experiments on MIMIC-III and MIMIC-IV demonstrate that RePrompT consistently outperforms both EHR-based and LLM-based baselines across multiple clinical prediction tasks.

  • 5 authors
·
Apr 19

Read, Revise, Repeat: A System Demonstration for Human-in-the-loop Iterative Text Revision

Revision is an essential part of the human writing process. It tends to be strategic, adaptive, and, more importantly, iterative in nature. Despite the success of large language models on text revision tasks, they are limited to non-iterative, one-shot revisions. Examining and evaluating the capability of large language models for making continuous revisions and collaborating with human writers is a critical step towards building effective writing assistants. In this work, we present a human-in-the-loop iterative text revision system, Read, Revise, Repeat (R3), which aims at achieving high quality text revisions with minimal human efforts by reading model-generated revisions and user feedbacks, revising documents, and repeating human-machine interactions. In R3, a text revision model provides text editing suggestions for human writers, who can accept or reject the suggested edits. The accepted edits are then incorporated into the model for the next iteration of document revision. Writers can therefore revise documents iteratively by interacting with the system and simply accepting/rejecting its suggested edits until the text revision model stops making further revisions or reaches a predefined maximum number of revisions. Empirical experiments show that R3 can generate revisions with comparable acceptance rate to human writers at early revision depths, and the human-machine interaction can get higher quality revisions with fewer iterations and edits. The collected human-model interaction dataset and system code are available at https://github.com/vipulraheja/IteraTeR. Our system demonstration is available at https://youtu.be/lK08tIpEoaE.

  • 5 authors
·
Apr 7, 2022

Can AI Reviewers See Your Efforts to Improve Your Paper? A Large-Scale Study of Paper Revision Trajectories

AI reviewers are increasingly used to assess scientific manuscripts, yet it remains unclear whether their judgments reflect the improvements authors make through revision. We investigate this question using PaperTrajectory-2026, the 2026 release of PaperTrajectory, a dataset of 6,959 paper trajectories across five AI conferences, with automatic annotations of changes along 14 dimensions and separate judgments of overall quality. The annotations show that major improvements emphasize empirical evidence and framing, while later revisions tend toward incremental improvement. Using independent assessments of manuscript versions from eight AI reviewers, we examine whether annotated major improvements receive higher scores, which revision dimensions are associated with score changes, and whether user opinions can outweigh observed revision gains. Every reviewer leaves scores unchanged on most major improvements, and agreement on the direction of score changes is weak. Revision dimensions show some reviewer-specific associations with score increases, but provide limited predictive discrimination and no consistent guide across reviewers. Even when a revision earns a higher neutral score, a brief negative user opinion can erase or reverse that advantage, with substantial variation across reviewers. These findings show that substantive revisions are not consistently reflected in review scores and that observed scoring gains can be vulnerable to user framing, motivating assessments that connect manuscript evidence to overall judgments and remain stable when no scientific evidence changes.

umd-zhou-lab Tianyi Lab
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Oct 31 2

CT-ΔBench: A Benchmark for Longitudinal 3D Medical Imaging Difference Reporting with Vision-Language Models

In medical imaging, the clinical value of Computed Tomography (CT) lies not only in depicting current disease status, but crucially in enabling longitudinal comparison of serial scans to determine disease evolution, a process that underpins response assessment, recurrence detection, and ongoing patient management. Yet, despite this central role of temporal comparison in clinical decision-making, existing medical foundation models remain largely confined to single-study understanding, leaving temporally grounded cross-examination insufficiently addressed. To address this gap, we study longitudinal imaging difference reporting, a task in which a model takes two temporally separated scans from the same patient and generates a clinically meaningful report describing interval changes between them. We introduce CT-ΔBench, a dedicated benchmark for this task with patient-level splitting to prevent information leakage. To better evaluate this task beyond surface-level text similarity, we further develop change-aware metrics specifically designed to capture clinically meaningful longitudinal changes, and conduct an independent physician validation to assess the reliability of the synthesized references and event extraction pipeline. We also compare direct paired-CT reasoning with an indirect two-stage pipeline that first generates single-timepoint reports and then performs textual differencing. Finally, we propose DeltaMed, a baseline model for direct paired-CT difference reporting, and train it on the benchmark training set. Together, these contributions lay the groundwork for temporally aware medical foundation models that better reflect real-world longitudinal clinical reasoning.

  • 4 authors
·
Aug 11

StraTune: Adaptive Selection of Revision Operators for Self-Evolving LLM Skills

Large language models (LLMs) can learn reusable textual skills from execution feedback without updating their parameters, but effectively deciding how to revise these skills remains a key challenge. Existing methods typically rely on a fixed revision operator, a search strategy and the revision forms applied under it. However, we observe that no single revision operator consistently performs best across tasks, and repeatedly applying an unsuitable operator can limit further improvement. We propose StraTune (strategy-guided skill tuning), which lets a frozen optimizer LLM choose the revision operator at every round from the optimization state, which is defined as the current execution feedback together with the recorded outcomes of earlier strategies and forms. Candidate skills from every revision operator pass one candidate evaluation, which screens for gains and regressions on a small sample set and validates them on a larger one, and every outcome is written back to the optimization state for later choices. Across four benchmarks and two LLM settings, StraTune outperforms all five baselines in most settings. Ablations attribute the gains to the adaptive choice of the revision operator, since fixed, random, scheduled, and bandit strategy choices all score lower, and skills learned with a small target LLM also improve a stronger one. Code and learned skills are available at https://github.com/seai-lab/StraTune.

  • 5 authors
·
Sep 25

Enforcing temporal consistency in Deep Learning segmentation of brain MR images

Longitudinal analysis has great potential to reveal developmental trajectories and monitor disease progression in medical imaging. This process relies on consistent and robust joint 4D segmentation. Traditional techniques are dependent on the similarity of images over time and the use of subject-specific priors to reduce random variation and improve the robustness and sensitivity of the overall longitudinal analysis. This is however slow and computationally intensive as subject-specific templates need to be rebuilt every time. The focus of this work to accelerate this analysis with the use of deep learning. The proposed approach is based on deep CNNs and incorporates semantic segmentation and provides a longitudinal relationship for the same subject. The proposed approach is based on deep CNNs and incorporates semantic segmentation and provides a longitudinal relationship for the same subject. The state of art using 3D patches as inputs to modified Unet provides results around {0.91 pm 0.5} Dice and using multi-view atlas in CNNs provide around the same results. In this work, different models are explored, each offers better accuracy and fast results while increasing the segmentation quality. These methods are evaluated on 135 scans from the EADC-ADNI Harmonized Hippocampus Protocol. Proposed CNN based segmentation approaches demonstrate how 2D segmentation using prior slices can provide similar results to 3D segmentation while maintaining good continuity in the 3D dimension and improved speed. Just using 2D modified sagittal slices provide us a better Dice and longitudinal analysis for a given subject. For the ADNI dataset, using the simple UNet CNN technique gives us {0.84 pm 0.5} and while using modified CNN techniques on the same input yields {0.89 pm 0.5}. Rate of atrophy and RMS error are calculated for several test cases using various methods and analyzed.

  • 2 authors
·
Jun 13, 2019

Rethinking Self-Evolving Agent Skills: Feedback Dynamics over Multiple Rounds

Self-evolving skill systems promise to improve agents by turning execution feedback into persistent skill updates without changing the underlying model. Yet it remains unclear when further evolution helps, how successful and failed trajectories shape revision, and whether extra test-time computation can recover the same gains. To address these questions, we present a controlled evaluation framework across five benchmarks and three models. Our primary study contains 42 feedback runs across 14 supported model-benchmark settings. Within each setting, we hold the executor and optimizer configuration, revision procedure, validation rule, and round budget fixed, while varying only the feedback shown to the optimizer: successes and failures (Normal), failures only, or successes only. Evolution is sparse: only 55 of 388 candidates establish byte-distinct validation bests. Validation-based selection chooses an evolved skill in 11 of 14 settings, nine of which improve released-test performance. All 11 selections come from feedback conditions that include failed trajectories, although the relative ranking of Normal and Fail-only varies across settings. Validation and downstream evaluations on test, robustness, and transfer sometimes favor different feedback views. A broader SearchQA analysis covering eight models shows similarly sparse, feedback-dependent dynamics. In the GPT-5.5 test-time-scaling controls, oracle Parallel Sampling comes within 0.43 points of the evolved SearchQA skill but remains 30.96 points behind on SpreadsheetBench; Sequential Refinement recovers neither gain. Overall, persistent skill self-evolution is better understood as sparse, validation-filtered search with model- and benchmark-dependent returns, rather than steady improvement from additional rounds. The implementation is available at https://github.com/HKUST-KnowComp/rethinkskill.

  • 12 authors
·
Jul 30

The 17% Gap: Quantifying Epistemic Decay in AI-Assisted Survey Papers

The adoption of Large Language Models (LLMs) in scientific writing promises efficiency but risks introducing informational entropy. While "hallucinated papers" are a known artifact, the systematic degradation of valid citation chains remains unquantified. We conducted a forensic audit of 50 recent survey papers in Artificial Intelligence (N=5,514 citations) published between September 2024 and January 2026. We utilized a hybrid verification pipeline combining DOI resolution, Crossref metadata analysis, Semantic Scholar queries, and fuzzy text matching to distinguish between formatting errors ("Sloppiness") and verifiable non-existence ("Phantoms). We detect a persistent 17.0% Phantom Rate -- citations that cannot be resolved to any digital object despite aggressive forensic recovery. Diagnostic categorization reveals three distinct failure modes: pure hallucinations (5.1%), hallucinated identifiers with valid titles (16.4%), and parsing-induced matching failures (78.5%). Longitudinal analysis reveals a flat trend (+0.07 pp/month), suggesting that high-entropy citation practices have stabilized as an endemic feature of the field. The scientific citation graph in AI survey literature exhibits "link rot" at scale. This suggests a mechanism where AI tools act as "lazy research assistants," retrieving correct titles but hallucinating metadata, thereby severing the digital chain of custody required for reproducible science.

  • 1 authors
·
Jan 23

Longitudinal causal inference under informative missingness using the self-censoring model

Longitudinal observational data are often subject to informative missingness. For example, in healthcare research using electronic health records, covariates and outcomes are measured only when patients interact with the healthcare system. Whether these data are observed usually depends on the unobserved variable values themselves, introducing a common form of data missing not at random. We develop identification and estimation methods for the effects of longitudinal modified treatment policies under a self-censoring model which explicitly models this dependence. We consider effects of treatments that can be modified only at measurement times (e.g., interactions with the heathcare system). We study two settings: one in which the observed history suffices for treatment confounding control, and another in which confounder control requires covariate values that were not measured at missed visits. In both settings, we combine longitudinal causal identification with shadow-variable conditional moment restrictions to obtain recursive identification formulas for the counterfactual outcome mean. We derive gradients of the pathwise derivatives and second-order remainder expansions, and use these results to construct estimators that accommodate machine learning for nuisance-function estimation. Under suitable product-rate conditions and cross-fitting, the estimators are asymptotically linear and permit root-n inference, including simultaneous inference across outcome times. We also describe conditional-moment learning and ensemble approaches for estimating the nuisance functions required by our approach, together with a pool-and-smooth strategy that borrows information across sparsely measured outcomes.

  • 1 authors
·
Oct 5

LoMeVQA: A Comprehensive Benchmark for Longitudinal Medical VQA

In clinical practice, patients often undergo multiple imaging examinations over successive visits, yielding longitudinal data. Modeling such temporal information is crucial for reliable assessment of disease progression and treatment response. However, despite the rapid advancement of multimodal large language models (MLLMs), longitudinal medical visual reasoning remains largely underexplored. To fill this gap, we propose LoMeVQA, a comprehensive benchmark consisting of 206K longitudinal visual question answering (VQA) pairs for temporal medical image analysis. LoMeVQA covers five tasks: progress classification, progress description, progress report generation, differential region grounding, and differential region description. To construct the dataset, we develop an automated pipeline that (1) organizes patient records chronologically, (2) extracts clinically meaningful entities via a medical knowledge graph, and (3) models their temporal evolution to guide large language models in generating high-quality longitudinal VQA pairs. Extensive evaluations demonstrate that both general-purpose and medical-domain MLLMs perform poorly on LoMeVQA, revealing substantial limitations in temporal reasoning. To address these limitations, we introduce MedLong-8B, which achieves state-of-the-art performance across all tasks. Beyond benchmarking, we conduct detailed analyses that uncover key failure modes and shed light on how to improve longitudinal medical visual reasoning. Our data is available at: https://github.com/pepperbubble/LoMeVQA

  • 7 authors
·
Jul 29

When OpenClaw Meets Hospital: Toward an Agentic Operating System for Dynamic Clinical Workflows

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and clinical decision making. Their reliable deployment in hospitals, however, remains constrained by safety risks, limited transparency, and inadequate mechanisms for handling longitudinal clinical context. Here we propose an architecture that adapts LLM agents to hospital environments. The design comprises four components: a restricted execution environment inspired by multi-user operating systems, a document-centric interaction model linking patient and clinician agents, a page-indexed memory architecture for longitudinal context management, and a curated library of composable medical skills. Implemented on top of OpenClaw, an open-source agent orchestration framework, this design provides the basis for an Agentic Operating System for Hospitals: a computing layer for coordinating clinical workflows while preserving safety, transparency, and auditability. To evaluate the memory component, we introduce manifest-guided retrieval for hierarchical navigation of longitudinal patient records. In a benchmark derived from the MIMIC-IV dataset (v2.2) comprising 100 de-identified patient records and 300 clinical queries stratified across three difficulty tiers (100 per tier), manifest-guided retrieval matched a metadata-filtered RAG baseline on overall recall (0.877 versus 0.876) while achieving 2.2x higher precision (0.779 versus 0.352) and retrieving fewer documents; on tier-3 longitudinal queries, manifest recall was 21% higher (0.846 versus 0.701), confirming that LLM-guided hierarchical navigation is most valuable when queries span multiple care episodes. These results outline a practical path toward hospital-scale agentic infrastructure.

  • 8 authors
·
Mar 20

A Review of Longitudinal Radiology Report Generation: Dataset Composition, Methods, and Performance Evaluation

Chest Xray imaging is a widely used diagnostic tool in modern medicine, and its high utilization creates substantial workloads for radiologists. To alleviate this burden, vision language models are increasingly applied to automate Chest Xray radiology report generation (CXRRRG), aiming for clinically accurate descriptions while reducing manual effort. Conventional approaches, however, typically rely on single images, failing to capture the longitudinal context necessary for producing clinically faithful comparison statements. Recently, growing attention has been directed toward incorporating longitudinal data into CXR RRG, enabling models to leverage historical studies in ways that mirror radiologists diagnostic workflows. Nevertheless, existing surveys primarily address single image CXRRRG and offer limited guidance for longitudinal settings, leaving researchers without a systematic framework for model design. To address this gap, this survey provides the first comprehensive review of longitudinal radiology report generation (LRRG). Specifically, we examine dataset construction strategies, report generation architectures alongside longitudinally tailored designs, and evaluation protocols encompassing both longitudinal specific measures and widely used benchmarks. We further summarize LRRG methods performance, alongside analyses of different ablation studies, which collectively highlight the critical role of longitudinal information and architectural design choices in improving model performance. Finally, we summarize five major limitations of current research and outline promising directions for future development, aiming to lay a foundation for advancing this emerging field.

  • 6 authors
·
Oct 14, 2025

Memory in Large Language Models: Mechanisms, Evaluation and Evolution

Under a unified operational definition, we define LLM memory as a persistent state written during pretraining, finetuning, or inference that can later be addressed and that stably influences outputs. We propose a four-part taxonomy (parametric, contextual, external, procedural/episodic) and a memory quadruple (location, persistence, write/access path, controllability). We link mechanism, evaluation, and governance via the chain write -> read -> inhibit/update. To avoid distorted comparisons across heterogeneous setups, we adopt a three-setting protocol (parametric only, offline retrieval, online retrieval) that decouples capability from information availability on the same data and timeline. On this basis we build a layered evaluation: parametric (closed-book recall, edit differential, memorization/privacy), contextual (position curves and the mid-sequence drop), external (answer correctness vs snippet attribution/faithfulness), and procedural/episodic (cross-session consistency and timeline replay, E MARS+). The framework integrates temporal governance and leakage auditing (freshness hits, outdated answers, refusal slices) and uncertainty reporting via inter-rater agreement plus paired tests with multiple-comparison correction. For updating and forgetting, we present DMM Gov: coordinating DAPT/TAPT, PEFT, model editing (ROME, MEND, MEMIT, SERAC), and RAG to form an auditable loop covering admission thresholds, rollout, monitoring, rollback, and change audits, with specs for timeliness, conflict handling, and long-horizon consistency. Finally, we give four testable propositions: minimum identifiability; a minimal evaluation card; causally constrained editing with verifiable forgetting; and when retrieval with small-window replay outperforms ultra-long-context reading. This yields a reproducible, comparable, and governable coordinate system for research and deployment.

  • 7 authors
·
Sep 23, 2025

Enhanced Contrastive Learning with Multi-view Longitudinal Data for Chest X-ray Report Generation

Automated radiology report generation offers an effective solution to alleviate radiologists' workload. However, most existing methods focus primarily on single or fixed-view images to model current disease conditions, which limits diagnostic accuracy and overlooks disease progression. Although some approaches utilize longitudinal data to track disease progression, they still rely on single images to analyze current visits. To address these issues, we propose enhanced contrastive learning with Multi-view Longitudinal data to facilitate chest X-ray Report Generation, named MLRG. Specifically, we introduce a multi-view longitudinal contrastive learning method that integrates spatial information from current multi-view images and temporal information from longitudinal data. This method also utilizes the inherent spatiotemporal information of radiology reports to supervise the pre-training of visual and textual representations. Subsequently, we present a tokenized absence encoding technique to flexibly handle missing patient-specific prior knowledge, allowing the model to produce more accurate radiology reports based on available prior knowledge. Extensive experiments on MIMIC-CXR, MIMIC-ABN, and Two-view CXR datasets demonstrate that our MLRG outperforms recent state-of-the-art methods, achieving a 2.3% BLEU-4 improvement on MIMIC-CXR, a 5.5% F1 score improvement on MIMIC-ABN, and a 2.7% F1 RadGraph improvement on Two-view CXR.

  • 7 authors
·
Feb 27, 2025

What Should World Models Forget? Stratified Retention for Continual Adaptation

Continual learning treats degradation on previously seen data as evidence of failure, a convention inherited from settings with a stationary prediction target, where a correct label remains correct indefinitely. World models do not satisfy this condition. Their prediction target is the environment, which changes, so knowledge that was accurate when acquired may later become false, and discarding it is required behavior rather than a defect. Non-stationary ground truth is well studied in the concept drift literature and in the temporal factuality of language models, but has not been formulated for world models, which are distinctive in that they also encode knowledge that must never be revised. We argue that continual world models require retention stratified by invariance timescale, separating invariants such as physics and object permanence, which must never be revised, from instance-level facts that should be revised as soon as the environment changes. Standard forgetting metrics cannot distinguish a world model that has correctly revised outdated knowledge from one that has suffered catastrophic forgetting, and consequently rank a frozen model highest, while existing physical-reasoning benchmarks evaluate only frozen checkpoints. We propose differential retention, which reports invariant regression testing across the adaptation stream jointly with revision latency, without aggregation.

  • 3 authors
·
Oct 1

Causal Longitudinal Prior-Fitted Networks for Counterfactual Outcome Prediction

Longitudinal treatment decisions require predicting potential outcomes under future treatment sequences in the presence of time-varying confounding, heterogeneous patient dynamics, and limited domain-specific data. Existing longitudinal causal estimators typically train a new model for each cohort or simulator. We introduce Causal Longitudinal Prior-Fitted Networks (CausalLongPFN), a prior-fitted in-context predictor for longitudinal causal prediction. The model is pretrained entirely on synthetic episodes sampled from a broad prior over temporal structural causal models, exposing it to treatment-confounder feedback, latent heterogeneity, nonlinear state evolution, delayed effects, and cumulative treatment responses. At test time, CausalLongPFN is frozen: it conditions on support trajectories, a query history, and a proposed future treatment sequence, and returns a predictive distribution over future outcomes without gradient updates or propensity-model fitting. Multi-step predictions are obtained by recursively applying the one-step predictor under the specified treatment sequence. We evaluate on branchable cancer, HIV, and warfarin benchmarks with ground-truth counterfactual labels, and on factual-only rolling-origin prediction in MIMIC-III ICU trajectories. CausalLongPFN is competitive with domain-trained longitudinal baselines on counterfactual benchmarks and performs strongly on factual MIMIC-III prediction, suggesting that broad synthetic causal pretraining can provide a useful frozen alternative when repeated domain-specific training is costly or impractical.

  • 5 authors
·
Jun 3

Incremental Open-Ended Deep Research with Structured Harness

Existing Open-Ended Deep Research (OEDR) systems primarily generate reports from scratch, making them inefficient for scenarios where research reports need to be continuously maintained as new information emerges. We introduce Incremental Open-Ended Deep Research (Incremental-OEDR), a research setting that treats a report as an evolving research state and incrementally updates it by preserving valid knowledge, revising outdated or incomplete content, and incorporating newly available information. To support this setting, we propose Structured Harness, which represents reports as structured collections of outlines, sections, and supporting evidence, and provides structured retrieval, a persistent structured evidence pool, and structured generation for selective report updating and evidence reuse. We further establish a temporal evaluation framework spanning ten years, with Single-Step Task and Long-Chain Task to evaluate incremental updates over both individual transitions and long-term update chains. Extensive Experiments on DeepResearch Bench and DeepConsult under both the Open-source Configuration (OC) and Proprietary Configuration (PC) show that Incremental-OEDR maintains competitive report quality while substantially improving report continuity and reducing research costs. As shown in Figure~fig:profile, it achieves up to 0.51 higher content-level ROUGE-L F1, 0.63 higher outline-level EM F1, 33\% lower token consumption, and 61\% fewer search calls than OEDR on DeepResearch Bench. For more details, please refer to our project page: https://ioedr-project.github.io/.

  • 2 authors
·
Oct 7 3

Revision or Re-Solving? Decomposing Second-Pass Gains in Multi-LLM Pipelines

Multi-LLM revision pipelines, in which a second model reviews and improves a draft produced by a first, are widely assumed to derive their gains from genuine error correction. We question this assumption with a controlled decomposition experiment that uses four matched conditions to separate second-pass gains into three additive components: re-solving, scaffold, and content. We evaluate this design across two model pairs on three benchmarks spanning knowledge-intensive MCQ and competitive programming. Our results show that the gains of multi-LLM revision are not monolithic, but depend on task structure, draft quality, and the type of draft information. On MCQ tasks, where the answer space is constrained and drafts provide little structural guidance, most gains are consistent with stronger-model re-solving, and directly routing queries to the stronger model can be more effective than revising a weak draft. On code generation tasks, however, two-stage prompting remains useful because even semantically null drafts can provide substantial structural scaffolding, while weak draft content can be harmful. Finally, role-reversed experiments show that strong drafts clearly benefit weak reviewers. Ultimately, our findings demonstrate that the utility of multi-LLM revision is dynamically bottlenecked by task structure and draft quality, necessitating more targeted pipeline designs rather than blanket revision strategies.

Brain Latent Progression: Individual-based Spatiotemporal Disease Progression on 3D Brain MRIs via Latent Diffusion

The growing availability of longitudinal Magnetic Resonance Imaging (MRI) datasets has facilitated Artificial Intelligence (AI)-driven modeling of disease progression, making it possible to predict future medical scans for individual patients. However, despite significant advancements in AI, current methods continue to face challenges including achieving patient-specific individualization, ensuring spatiotemporal consistency, efficiently utilizing longitudinal data, and managing the substantial memory demands of 3D scans. To address these challenges, we propose Brain Latent Progression (BrLP), a novel spatiotemporal model designed to predict individual-level disease progression in 3D brain MRIs. The key contributions in BrLP are fourfold: (i) it operates in a small latent space, mitigating the computational challenges posed by high-dimensional imaging data; (ii) it explicitly integrates subject metadata to enhance the individualization of predictions; (iii) it incorporates prior knowledge of disease dynamics through an auxiliary model, facilitating the integration of longitudinal data; and (iv) it introduces the Latent Average Stabilization (LAS) algorithm, which (a) enforces spatiotemporal consistency in the predicted progression at inference time and (b) allows us to derive a measure of the uncertainty for the prediction at the global and voxel level. We train and evaluate BrLP on 11,730 T1-weighted (T1w) brain MRIs from 2,805 subjects and validate its generalizability on an external test set comprising 2,257 MRIs from 962 subjects. Our experiments compare BrLP-generated MRI scans with real follow-up MRIs, demonstrating state-of-the-art accuracy compared to existing methods. The code is publicly available at: https://github.com/LemuelPuglisi/BrLP.

  • 3 authors
·
Feb 12, 2025

Continual Learning Exam: Benchmarking Long-Horizon RSI and Experiential Learning in LLM Agents

Continual learning is the ability of LLM agents to improve over time by acquiring, refining, and applying knowledge from experience while retaining useful prior knowledge. It is essential for agents learning over long time horizons, yet current evaluations largely assess individual task performance rather than improvement through accumulated experience. We introduce Continual Learning Exam (CLE), a large-scale benchmark developed by 50+ domain experts to measure experience-driven improvement in realistic professional workflows. CLE comprises 120 human-authored tasks, each organised as a five-level ladder, yielding 600 levels spanning 89 professional roles across 12 occupational domains. Agents must pass each level to unlock the next, with later levels building on experience accumulated during earlier assignments. An evaluation agent assesses each submission against human-authored rubrics. We compare a single-submission setting with one that provides diagnostic feedback after failure and allows one revision. Across 17 harness-model configurations using frontier LLMs, feedback and revision yield a median completion gain of 5.3 percentage points. Yet the best-performing system clears only 47.7% of levels and completes all five levels in just 23.3% of tasks, highlighting the difficulty of sustained learning from experience for existing frontier LLMs. As such, the dataset can also be used to post-train LLMs to strengthen their continual learning capabilities.

arXivEdits: Understanding the Human Revision Process in Scientific Writing

Scientific publications are the primary means to communicate research discoveries, where the writing quality is of crucial importance. However, prior work studying the human editing process in this domain mainly focused on the abstract or introduction sections, resulting in an incomplete picture. In this work, we provide a complete computational framework for studying text revision in scientific writing. We first introduce arXivEdits, a new annotated corpus of 751 full papers from arXiv with gold sentence alignment across their multiple versions of revision, as well as fine-grained span-level edits and their underlying intentions for 1,000 sentence pairs. It supports our data-driven analysis to unveil the common strategies practiced by researchers for revising their papers. To scale up the analysis, we also develop automatic methods to extract revision at document-, sentence-, and word-levels. A neural CRF sentence alignment model trained on our corpus achieves 93.8 F1, enabling the reliable matching of sentences between different versions. We formulate the edit extraction task as a span alignment problem, and our proposed method extracts more fine-grained and explainable edits, compared to the commonly used diff algorithm. An intention classifier trained on our dataset achieves 78.9 F1 on the fine-grained intent classification task. Our data and system are released at tiny.one/arxivedits.

  • 3 authors
·
Oct 26, 2022

Excision Score: Evaluating Edits with Surgical Precision

Many tasks revolve around editing a document, whether code or text. We formulate the revision similarity problem to unify a wide range of machine learning evaluation problems whose goal is to assess a revision to an existing document. We observe that revisions usually change only a small portion of an existing document, so the existing document and its immediate revisions share a majority of their content. We formulate five adequacy criteria for revision similarity measures, designed to align them with human judgement. We show that popular pairwise measures, like BLEU, fail to meet these criteria, because their scores are dominated by the shared content. They report high similarity between two revisions when humans would assess them as quite different. This is a fundamental flaw we address. We propose a novel static measure, Excision Score (ES), which computes longest common subsequence (LCS) to remove content shared by an existing document with the ground truth and predicted revisions, before comparing only the remaining divergent regions. This is analogous to a surgeon creating a sterile field to focus on the work area. We use approximation to speed the standard cubic LCS computation to quadratic. In code-editing evaluation, where static measures are often used as a cheap proxy for passing tests, we demonstrate that ES surpasses existing measures. When aligned with test execution on HumanEvalFix, ES improves over its nearest competitor, SARI, by 12% Pearson correlation and by >21% over standard measures like BLEU. The key criterion is invariance to shared context; when we perturb HumanEvalFix with increased shared context, ES' improvement over SARI increases to 20% and >30% over standard measures. ES also handles other corner cases that other measures do not, such as correctly aligning moved code blocks, and appropriately rewarding matching insertions or deletions.

  • 4 authors
·
Oct 24, 2025

Presentation, Not Mechanism: A Render Confound in Deprecation-Aware Memory Evaluation

AI systems increasingly retrieve from records that revise themselves: issue threads, encyclopedic histories, policy logs, and long conversations. The challenge is not only finding relevant evidence, but deciding which claims remain in force, which were superseded, and when to abstain. Structured memories promise to solve this with typed edges, temporal updates, and conflict status, yet evaluations often change mechanism and prompt presentation together. We study this as Evidence-State Revision, comparing flat retrieval, coarse edge invalidation, and fine-grained RevisionLedger on 2,907 high-agreement questions from GitHub, multi-repo issue histories, Wikipedia, and DyKnow-style temporal streams. A render-matched control (same layout, deprecation disabled) reveals the central confound: when a value is changed and later restored, RevisionLedger appears to beat a flat baseline by +0.182, but almost all the gain comes from easier presentation; the fine-grained mechanism residual is indistinguishable from zero (+0.021 to +0.025 across two judge families). After presentation is controlled, coarse invalidation is the only mechanism that pays for current-state queries, beating the fine ledger by 0.084; the same query-sufficiency principle says provenance mainly needs retained invalidated evidence, not richer typing. Memory evaluations should hold render fixed, and deprecation-aware systems should deploy the coarsest retained state that covers their queries.

  • 8 authors
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Jul 16

Causal Edit Serialization

Standard autoregressive language models generate text sequentially, but revision requires referring back to tokens in the input context or those already generated. Causal Edit Serialization (CES) is introduced as a framework for expressing such revisions within the same causal token stream. Special pointer tokens are paired with predicted source addresses, allowing insertion, deletion, replacement, copying and movement to be localized explicitly. A lightweight localization head and dual-index rotary position encoding support both address prediction and conditioning on previously emitted pointers, while retaining a standard causal attention mask. A pretraining procedure combines ordinary language modeling with serialized repairs derived from random corruptions, model-generated edits and repeated text. Across model scales and editing baselines, CES models demonstrate complete applied edits with modestly higher clean-text bits per byte than clean autoregressive models. Supervised and reinforcement-learning post-training provide a grammatical-error-correction proof of concept, producing more beneficial than harmful changes under reference-blind model judging. Correct repair programs also improve subsequent text prediction while the original context and its cached states are retained. CES provides a common interface for generation and localized revision, with potential extensions to iterative refinement and additional pointer-addressed transformations.

  • 1 authors
·
Oct 15

ActReview: Rebuttal-Guided Training Data and Rubric Rewards for Actionable Peer Review Generation

As LLMs are increasingly used for pre-submission self-review, there is growing demand for feedback that not only identifies weaknesses but also guides authors toward concrete revisions. We study this as Actionable Peer-review Generation and decompose it into two subtasks: diagnostic claim generation and revision suggestion generation. We introduce ActReview, a rebuttal-guided post-training framework that connects paper-specific diagnoses to concrete, grounded revision plans. Our central insight is that author rebuttals reveal plausible actions for addressing reviewer concerns and can therefore provide latent supervision for revision-oriented feedback. From real review-rebuttal threads on OpenReview, we construct ActReview-40K by aligning reviewer weaknesses with author responses and grounding the resulting feedback in localized paper evidence. We post-train Qwen3-8B-Base with multi-task supervised fine-tuning followed by GRPO using candidate-aware, weakness-specific rubric rewards. We also introduce ActReview-Bench, a human-curated benchmark of 1,000 instances for evaluating diagnostic quality and revision usefulness. Experiments show that ActReview outperforms prior specialized review-generation models on actionability and grounding while remaining competitive with strong prompt-based LLMs. Human evaluation confirms improved revision usefulness while revealing a remaining gap in technical accuracy, and additional analyses support generalization to held-out papers and robustness across independent judges.

When History Helps and Hurts: Selective History Use across Multimodal Turns

Reliable multimodal interaction depends on selective use of conversational history: an earlier question may remain relevant while its previous answer is outdated, whereas a current request may depend on historical evidence despite conflicting new observations. Existing multi-turn evaluations rarely separate these history-use demands from underlying question difficulty. To address this gap, we introduce ReTurn, a benchmark of 7,000 base tasks spanning visual and audio evidence for evaluating selective history use. For task-carrying history, Reconfirm/Reground require applying a historical question to current media while varying historical agreement; for evidence-carrying history, Retrieve/Rebind require answering a current question using historical media while varying current-media competition. Each pair preserves the target question, media, and answer. Tasks support open-ended and multiple-choice evaluation, with matched single-turn counterparts serving as answerability references. Across 13 omni-modal, vision-language, and audio-language models, median model-level open-ended accuracy falls from 93.7% with direct input to 72.3% in conversation. Behavioral probes show that high question recall can coexist with weaker task application, while competing media can redirect answers away from historical targets. Supervised adaptation yields only partial gains. ReTurn provides a controlled framework for assessing whether multimodal models select and use the historical information required by each request.

  • 5 authors
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Oct 8

REVES: REvision and VErification--Augmented Training for Test-Time Scaling

Test-time scaling via sequential revision has emerged as a powerful paradigm for enhancing Large Language Model (LLM) reasoning. However, standard post-training methods primarily optimize single-shot objectives, creating a fundamental misalignment with multi-step inference dynamics. While recent work treats this as multi-turn reinforcement learning (RL), conventional approaches optimize over the multi-step trajectories directly, failing to further exploit the high-quality mistakes in intermediate steps that model can learn from correcting them. We propose a two-stage iterative framework that alternates between online data/prompt augmentation and policy optimization. By converting the intermediate steps (``near-miss'' answers) in the successful recovery trajectories into decoupled revision and verification prompts, our approach concentrates training on both effective answer transformation and error identification. This approach enables efficient off-policy data generation and reduces the computational overhead of long-horizon sampling compared to standard multi-turn RL. On LiveCodeBench, using publicly available test cases as feedback, we observe gains of +6.5 points over the RL baseline and +4.0 points over standard multi-turn training. Beyond coding, our approach matches the previously reported SOTA result on circle packing while using the smallest base model (4B) and far fewer rollouts than the much larger evolutionary search systems. Math results under ground-truth verification further confirm improved correction ability. It also generalizes to out-of-distribution constraint-satisfaction puzzles such as n\_queens and mini\_sudoku, where correctness is defined entirely by problem constraints. Code is available at https://github.com/yxliu02/REVES.git.

  • 9 authors
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Jun 16 1

LitLLMs, LLMs for Literature Review: Are we there yet?

Literature reviews are an essential component of scientific research, but they remain time-intensive and challenging to write, especially due to the recent influx of research papers. This paper explores the zero-shot abilities of recent Large Language Models (LLMs) in assisting with the writing of literature reviews based on an abstract. We decompose the task into two components: 1. Retrieving related works given a query abstract, and 2. Writing a literature review based on the retrieved results. We analyze how effective LLMs are for both components. For retrieval, we introduce a novel two-step search strategy that first uses an LLM to extract meaningful keywords from the abstract of a paper and then retrieves potentially relevant papers by querying an external knowledge base. Additionally, we study a prompting-based re-ranking mechanism with attribution and show that re-ranking doubles the normalized recall compared to naive search methods, while providing insights into the LLM's decision-making process. In the generation phase, we propose a two-step approach that first outlines a plan for the review and then executes steps in the plan to generate the actual review. To evaluate different LLM-based literature review methods, we create test sets from arXiv papers using a protocol designed for rolling use with newly released LLMs to avoid test set contamination in zero-shot evaluations. We release this evaluation protocol to promote additional research and development in this regard. Our empirical results suggest that LLMs show promising potential for writing literature reviews when the task is decomposed into smaller components of retrieval and planning. Our project page including a demonstration system and toolkit can be accessed here: https://litllm.github.io.

  • 8 authors
·
Dec 14, 2024

SADM: Sequence-Aware Diffusion Model for Longitudinal Medical Image Generation

Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state, i.e., via image generation. However, most of the medical image generation tasks only rely on the input from a single image, thus ignoring the sequential dependency even when longitudinal data is available. Sequence-aware deep generative models, where model input is a sequence of ordered and timestamped images, are still underexplored in the medical imaging domain that is featured by several unique challenges: 1) Sequences with various lengths; 2) Missing data or frame, and 3) High dimensionality. To this end, we propose a sequence-aware diffusion model (SADM) for the generation of longitudinal medical images. Recently, diffusion models have shown promising results in high-fidelity image generation. Our method extends this new technique by introducing a sequence-aware transformer as the conditional module in a diffusion model. The novel design enables learning longitudinal dependency even with missing data during training and allows autoregressive generation of a sequence of images during inference. Our extensive experiments on 3D longitudinal medical images demonstrate the effectiveness of SADM compared with baselines and alternative methods. The code is available at https://github.com/ubc-tea/SADM-Longitudinal-Medical-Image-Generation.

  • 5 authors
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Dec 15, 2022

Retriever-and-Memory: Towards Adaptive Note-Enhanced Retrieval-Augmented Generation

Retrieval-Augmented Generation (RAG) mitigates issues of the factual errors and hallucinated outputs generated by Large Language Models (LLMs) in open-domain question-answering tasks (OpenQA) via introducing external knowledge. For complex QA, however, existing RAG methods use LLMs to actively predict retrieval timing and directly use the retrieved information for generation, regardless of whether the retrieval timing accurately reflects the actual information needs, or sufficiently considers prior retrieved knowledge, which may result in insufficient information gathering and interaction, yielding low-quality answers. To address these, we propose a generic RAG approach called Adaptive Note-Enhanced RAG (Adaptive-Note) for complex QA tasks, which includes the iterative information collector, adaptive memory reviewer, and task-oriented generator, while following a new Retriever-and-Memory paradigm. Specifically, Adaptive-Note introduces an overarching view of knowledge growth, iteratively gathering new information in the form of notes and updating them into the existing optimal knowledge structure, enhancing high-quality knowledge interactions. In addition, we employ an adaptive, note-based stop-exploration strategy to decide "what to retrieve and when to stop" to encourage sufficient knowledge exploration. We conduct extensive experiments on five complex QA datasets, and the results demonstrate the superiority and effectiveness of our method and its components. The code and data are at https://github.com/thunlp/Adaptive-Note.

  • 12 authors
·
Oct 11, 2024

Continual Learning Mechanisms Compose for Long-Horizon Memorization

Language models may need to internalize information that arrives over time and retain it through many subsequent updates. To study this challenge, we introduce long-horizon memorization, a setting in which a model learns 100 query-answer tasks through continual supervised fine-tuning without retaining earlier training examples or receiving task identifiers at inference. Sequential updates cause catastrophic forgetting, and no single continual learning mechanism we evaluate maintains strong retention at this horizon. We hypothesize that mechanisms addressing complementary sources of forgetting will be more effective when composed. We organize these compositions along two design dimensions. Data, function, and weight anchors specify what prior information each update should preserve, while low-rank allocation rules determine where successive updates are retained. To test this hypothesis systematically, we construct three distinct 100-task memorization datasets. We introduce task-level successive halving to search the combinatorial design space and use a factorial experiment to measure individual and interaction effects. Our best method combines all three anchors with merged LoRA, ranks among the top 3 methods in all datasets, and raises average final retention from 1.2% under naive sequential fine-tuning to 34.9%, a 28-fold improvement. The data anchor and merged LoRA provide the largest average gains and interact super-additively on all three datasets. Together, these results show that composing complementary mechanisms substantially improves long-horizon memorization beyond what any individual mechanism achieves.

LARC: Low-Rank Adaptive Residual Connections for Learning in Frozen Models

Low-Rank Adaptive Residual Connections (LARC) give a frozen model a compact numerical state that can learn from feedback. The map h+BAh adds a low-rank correction to a hidden representation. A slow state ρ learns starting factors across tasks; a private fast state Φ copies them, changes with feedback, and resets to the trained initialization. This report specifies an input-side realization of the numerical policy carrier in Memory-Mediated Learning Architecture and examines its factor-space dynamics and learning lifetime. We study a rank-4 input residual with 12,288 trainable parameters on a frozen MiniCPM5-1B-SFT substrate. In a four-candidate program-selection task, two feedback-gradient steps reduce expected query execution error by 24.65 and 36.65 percentage points relative to resetting to the respective trained static and post-adaptation initializations. These development results cover 16 parameter groups and three paired training seeds. A direct support-loss selection rule is much more accurate, reaching 0.78125% error. In a repository-balanced chronological replay of public continuous-integration jobs, retaining online updates raises half-Brier loss from 0.1274 to 0.1808. A fixed follow-up intervention records same-batch non-descent and inconsistent future benefit from shrinking updates. Together, the algebra and measurements distinguish residual capacity, adaptation relative to a starting point, and usefulness on later decisions.

  • 2 authors
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Sep 29

Enhancing Spatiotemporal Disease Progression Models via Latent Diffusion and Prior Knowledge

In this work, we introduce Brain Latent Progression (BrLP), a novel spatiotemporal disease progression model based on latent diffusion. BrLP is designed to predict the evolution of diseases at the individual level on 3D brain MRIs. Existing deep generative models developed for this task are primarily data-driven and face challenges in learning disease progressions. BrLP addresses these challenges by incorporating prior knowledge from disease models to enhance the accuracy of predictions. To implement this, we propose to integrate an auxiliary model that infers volumetric changes in various brain regions. Additionally, we introduce Latent Average Stabilization (LAS), a novel technique to improve spatiotemporal consistency of the predicted progression. BrLP is trained and evaluated on a large dataset comprising 11,730 T1-weighted brain MRIs from 2,805 subjects, collected from three publicly available, longitudinal Alzheimer's Disease (AD) studies. In our experiments, we compare the MRI scans generated by BrLP with the actual follow-up MRIs available from the subjects, in both cross-sectional and longitudinal settings. BrLP demonstrates significant improvements over existing methods, with an increase of 22% in volumetric accuracy across AD-related brain regions and 43% in image similarity to the ground-truth scans. The ability of BrLP to generate conditioned 3D scans at the subject level, along with the novelty of integrating prior knowledge to enhance accuracy, represents a significant advancement in disease progression modeling, opening new avenues for precision medicine. The code of BrLP is available at the following link: https://github.com/LemuelPuglisi/BrLP.

  • 3 authors
·
May 6, 2024

CRUD-RAG: A Comprehensive Chinese Benchmark for Retrieval-Augmented Generation of Large Language Models

Retrieval-Augmented Generation (RAG) is a technique that enhances the capabilities of large language models (LLMs) by incorporating external knowledge sources. This method addresses common LLM limitations, including outdated information and the tendency to produce inaccurate "hallucinated" content. However, the evaluation of RAG systems is challenging, as existing benchmarks are limited in scope and diversity. Most of the current benchmarks predominantly assess question-answering applications, overlooking the broader spectrum of situations where RAG could prove advantageous. Moreover, they only evaluate the performance of the LLM component of the RAG pipeline in the experiments, and neglect the influence of the retrieval component and the external knowledge database. To address these issues, this paper constructs a large-scale and more comprehensive benchmark, and evaluates all the components of RAG systems in various RAG application scenarios. Specifically, we have categorized the range of RAG applications into four distinct types-Create, Read, Update, and Delete (CRUD), each representing a unique use case. "Create" refers to scenarios requiring the generation of original, varied content. "Read" involves responding to intricate questions in knowledge-intensive situations. "Update" focuses on revising and rectifying inaccuracies or inconsistencies in pre-existing texts. "Delete" pertains to the task of summarizing extensive texts into more concise forms. For each of these CRUD categories, we have developed comprehensive datasets to evaluate the performance of RAG systems. We also analyze the effects of various components of the RAG system, such as the retriever, the context length, the knowledge base construction, and the LLM. Finally, we provide useful insights for optimizing the RAG technology for different scenarios.

  • 10 authors
·
Jan 30, 2024

A Self-Evolving Agent for Longitudinal Personal Health Management

Medical large language models and agents show strong single-encounter question answering and evidence interpretation but struggle to accumulate and govern experience across encounters. We present HealthJev, an open-source agent separating shared safety rules and medical knowledge from a private longitudinal memory and distilling lessons from completed cases. To filter out erroneous lessons before they affect future behaviour, we self-train JevGate, a lightweight System-One model that decides which lessons enter memory; each decision takes a median of 86 milliseconds and about 1,000 input tokens, sustaining experience accumulation at negligible run-time overhead. On a longitudinal benchmark of 90-day simulated daily interactions for 20 users built from real MIMIC-IV trajectories, HealthJev outperformed a memory-free ReAct agent and three memory-augmented frameworks, with all paired comparisons significant. Across six tasks spanning clinical records, medical imaging, genomics and clinical text, HealthJev improved every task with a mean gain of 13.3 percentage points over the base condition, surpassing all baselines. The frozen library transferred to six further backbones with macro-average gains of 6.8 to 15.1 percentage points, and one task's library brought gains on other tasks. These results indicate that governed, self-evolving memory supports longitudinal personal health management beyond single encounters. HealthJev is publicly available at https://github.com/HC-Guo/Self-Evolving_HealthJev.

  • 14 authors
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Jul 15

Autoregressive Search Engines: Generating Substrings as Document Identifiers

Knowledge-intensive language tasks require NLP systems to both provide the correct answer and retrieve supporting evidence for it in a given corpus. Autoregressive language models are emerging as the de-facto standard for generating answers, with newer and more powerful systems emerging at an astonishing pace. In this paper we argue that all this (and future) progress can be directly applied to the retrieval problem with minimal intervention to the models' architecture. Previous work has explored ways to partition the search space into hierarchical structures and retrieve documents by autoregressively generating their unique identifier. In this work we propose an alternative that doesn't force any structure in the search space: using all ngrams in a passage as its possible identifiers. This setup allows us to use an autoregressive model to generate and score distinctive ngrams, that are then mapped to full passages through an efficient data structure. Empirically, we show this not only outperforms prior autoregressive approaches but also leads to an average improvement of at least 10 points over more established retrieval solutions for passage-level retrieval on the KILT benchmark, establishing new state-of-the-art downstream performance on some datasets, while using a considerably lighter memory footprint than competing systems. Code and pre-trained models at https://github.com/facebookresearch/SEAL.

  • 6 authors
·
Apr 22, 2022

Time Present and Time Past: Benchmarking Large Language Models on Temporally Evolving Document Understanding

Evolving documents, such as laws, tax codes, and software documentation, are amended, replaced, and sometimes reverted over time, so a question has different correct answers at different dates. In contrast to encyclopedic knowledge, where an old fact is simply overwritten, an amendment is itself an official text that states what it replaces and when it takes effect, and the earlier version stays correct for its validity period. The central challenge is therefore version resolution, that is, identifying the version in force on the queried date. Existing temporal QA datasets treat time only as an annotation, so version resolution stays untested. We present TIDE, an expert-verified benchmark of 3,050 QA pairs over 644 official customs instruments issued between 1969 and 2025 by the Government of Bangladesh, covering eight task types over deeply code-mixed documents that are heterogeneous in layout and dated in two calendars. In addition, we evaluate nine recent LLMs under a single protocol across parametric, gold-context, and retrieval access, scored by a three-judge LLM council with a hard date gate separating correct meaning from correct time. The best macro-averaged accuracy is only 68.5%. Resolving a version from an implicit date reaches 59.7%, and detecting that the supplied version does not govern the query reaches only 26.7%. Models are more likely to find correct versions than to reject incorrect ones, and they tend to follow a confident parametric answer over the supplied authoritative text. All code and data are available at https://github.com/icsetepa44/TIDE

  • 7 authors
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Aug 8

Self-Evolving Agent Harness

Harness self-evolution revises an agent's software scaffolding, including prompts, memory, workflows, and executable components, while keeping model weights fixed. We formalize a feedback-driven process in which accepted revisions persist across runs. The framework separates update targets from proposal and admission mechanisms. It distinguishes changes to interpreted state from revisions to tools and code, repository-level control logic, and plugin composition. We characterize search through evolutionary optimization and examine its reliability through continual PAC-learning. Under explicit assumptions, the analysis yields an expected generalization bound, a retention bound conditional on historical regression budgets, and a high-probability admission rule using fresh, independent validation data. We examine how persistent harness revisions affect knowledge sharing and organizational workflows, with implications for scientific reliability, physical safety, and institutional accountability. Cases from prior work illustrate model--harness co-design, distributed execution, and plugin reuse. Reliable deployment requires continual validation as task distributions and evaluators change, with independent safeguards for learning, runtime privileges, and consequential actions. We provide a comprehensive 66-page discussion of related work, theory, algorithms, evaluation, applications, and the broader impact of Harness RSI, together with continuously updated code and supplementary materials, at https://github.com/zgcagi/Harness-RSI.

zgcagi ZGCAGI
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Oct 12 7

SkillAdam: Stable and Efficient Skill Evolution for Agents

Agent skills provide a lightweight way to equip frozen language-model agents with domain knowledge and procedural guidance, yet obtaining high-quality skills remains costly and difficult to scale. Expert-written skills require substantial human effort. Recent skill self-evolution methods automate an iterative loop that uses execution feedback to revise skills, but their heuristic update strategies often yield unstable optimization and low iteration efficiency. We identify two challenges in realizing stable and efficient skill self-evolution. Direction Stability requires effective corrections to accumulate rather than be overwritten by iteration-local feedback. Update Adaptivity requires the scope of each revision to reflect the consistency of recent case-level improvements. We introduce SkillAdam, an Adam-inspired framework for optimizing discrete and non-differentiable skill documents. As a functional analogue of Adam's first moment, an optimization memory records identified problems and the outcomes of prior solution attempts to stabilize the update direction. As a functional analogue of Adam's second moment, a volatility-driven edit budget tracks the history-weighted variation of recent case-level improvements and adaptively controls the update magnitude. Across seven benchmarks that span short- and long-horizon tasks, SkillAdam achieves state-of-the-art performance with more stable optimization dynamics. It also obtains stronger skills with substantially fewer optimization iterations and lower cost than prior methods. Code repository: https://github.com/ruc-datalab/SkillAdam

  • 10 authors
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Sep 7 1

ReVISE: Learning to Refine at Test-Time via Intrinsic Self-Verification

Self-awareness, i.e., the ability to assess and correct one's own generation, is a fundamental aspect of human intelligence, making its replication in large language models (LLMs) an important yet challenging task. Previous works tackle this by employing extensive reinforcement learning or rather relying on large external verifiers. In this work, we propose Refine via Intrinsic Self-Verification (ReVISE), an efficient and effective framework that enables LLMs to self-correct their outputs through self-verification. The core idea of ReVISE is to enable LLMs to verify their reasoning processes and continually rethink reasoning trajectories based on its verification. We introduce a structured curriculum based upon online preference learning to implement this efficiently. Specifically, as ReVISE involves two challenging tasks (i.e., self-verification and reasoning correction), we tackle each task sequentially using curriculum learning, collecting both failed and successful reasoning paths to construct preference pairs for efficient training. During inference, our approach enjoys natural test-time scaling by integrating self-verification and correction capabilities, further enhanced by our proposed confidence-aware decoding mechanism. Our experiments on various reasoning tasks demonstrate that ReVISE achieves efficient self-correction and significantly improves reasoning performance.

  • 5 authors
·
Feb 20, 2025 1

Continual Learning of Large Language Models: A Comprehensive Survey

The recent success of large language models (LLMs) trained on static, pre-collected, general datasets has sparked numerous research directions and applications. One such direction addresses the non-trivial challenge of integrating pre-trained LLMs into dynamic data distributions, task structures, and user preferences. Pre-trained LLMs, when tailored for specific needs, often experience significant performance degradation in previous knowledge domains -- a phenomenon known as "catastrophic forgetting". While extensively studied in the continual learning (CL) community, it presents new manifestations in the realm of LLMs. In this survey, we provide a comprehensive overview of the current research progress on LLMs within the context of CL. This survey is structured into four main sections: we first describe an overview of continually learning LLMs, consisting of two directions of continuity: vertical continuity (or vertical continual learning), i.e., continual adaptation from general to specific capabilities, and horizontal continuity (or horizontal continual learning), i.e., continual adaptation across time and domains (Section 3). We then summarize three stages of learning LLMs in the context of modern CL: Continual Pre-Training (CPT), Domain-Adaptive Pre-training (DAP), and Continual Fine-Tuning (CFT) (Section 4). Then we provide an overview of evaluation protocols for continual learning with LLMs, along with the current available data sources (Section 5). Finally, we discuss intriguing questions pertaining to continual learning for LLMs (Section 6). The full list of papers examined in this survey is available at https://github.com/Wang-ML-Lab/llm-continual-learning-survey.

  • 9 authors
·
Apr 25, 2024

Towards Lifelong Learning of Large Language Models: A Survey

As the applications of large language models (LLMs) expand across diverse fields, the ability of these models to adapt to ongoing changes in data, tasks, and user preferences becomes crucial. Traditional training methods, relying on static datasets, are increasingly inadequate for coping with the dynamic nature of real-world information. Lifelong learning, also known as continual or incremental learning, addresses this challenge by enabling LLMs to learn continuously and adaptively over their operational lifetime, integrating new knowledge while retaining previously learned information and preventing catastrophic forgetting. This survey delves into the sophisticated landscape of lifelong learning, categorizing strategies into two primary groups: Internal Knowledge and External Knowledge. Internal Knowledge includes continual pretraining and continual finetuning, each enhancing the adaptability of LLMs in various scenarios. External Knowledge encompasses retrieval-based and tool-based lifelong learning, leveraging external data sources and computational tools to extend the model's capabilities without modifying core parameters. The key contributions of our survey are: (1) Introducing a novel taxonomy categorizing the extensive literature of lifelong learning into 12 scenarios; (2) Identifying common techniques across all lifelong learning scenarios and classifying existing literature into various technique groups within each scenario; (3) Highlighting emerging techniques such as model expansion and data selection, which were less explored in the pre-LLM era. Through a detailed examination of these groups and their respective categories, this survey aims to enhance the adaptability, reliability, and overall performance of LLMs in real-world applications.

  • 4 authors
·
Jun 10, 2024

The Digital Divide in Generative AI: Evidence from Large Language Model Use in College Admissions Essays

Large language models (LLMs) have become popular writing tools among students and may expand access to high-quality feedback for students with less access to traditional writing support. At the same time, LLMs may standardize student voice or invite overreliance. This study examines how adoption of LLM-assisted writing varies across socioeconomic groups and how it relates to outcomes in a high-stakes context: U.S. college admissions. We analyze a de-identified longitudinal dataset of applications to a selective university from 2020 to 2024 (N = 81,663). Estimating LLM use using a distribution-based detector trained on synthetic and historical essays, we tracked how student writing changed as LLM use proliferated, how adoption differed by socioeconomic status (SES), and whether potential benefits translated equitably into admissions outcomes. Using fee-waiver status as a proxy for SES, we observe post-2023 convergence in surface-level linguistic features, with the largest changes in fee-waived and rejected applicants. Estimated LLM use rose sharply in 2024 across all groups, with disproportionately larger increases among lower SES applicants, consistent with an access hypothesis in which LLMs substitute for scarce writing support. However, increased estimated LLM use was more strongly associated with declines in predicted admission probability for lower SES applicants than for higher SES applicants, even after controlling for academic credentials and stylometric features. These findings raise concerns about equity and the validity of essay-based evaluation in an era of AI-assisted writing and provide the first large-scale longitudinal evidence linking LLM adoption, linguistic change, and evaluative outcomes in college admissions.

  • 5 authors
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Feb 18

CraftAlign: Feature-Grounded Evaluation and Revision Guidance for AI Stories

Large language models can now generate fluent and complete stories, yet many outputs still feel formulaic and unnatural because of cliches, over-explanation, linear causal progression, and stereotyped endings, an immediately recognizable AI flavor. Existing detection and evaluation methods often stop at source labels or holistic scores, while revision methods typically target predefined issues through localized edits, limiting their ability to support multiple plausible revision strategies or guide story-wide changes in information release, causal organization, and ending treatment. We introduce CraftAlign, a framework that aligns AI stories with the craft of human storytelling by both assessing Human/AI writing patterns and providing revision guidance. CraftAlign comprises two learned modules and an inference-time guidance pipeline. A feature estimator built on Qwen3.5-9B predicts 304 explicit writing features spanning style and narrative. A class-conditional energy model scores the resulting feature configuration against Human and AI writing patterns, conditioning on the original writing prompt when available. At inference time, CraftAlign applies schema-valid structured perturbations, selects changes that move the feature configuration toward the Human writing pattern, and converts them into natural-language guidance for a separate editor to rewrite the full story. Experiments show that CraftAlign accurately distinguishes Human and AI writing patterns and that its guidance outperforms revision baselines across editors and in a human study.

  • 8 authors
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Aug 1 1

Uncertainty-Aware Longitudinal Forecasting of Alzheimer's Disease Progression Using Deep Learning

Longitudinal modelling of Alzheimer's disease progression is clinically useful only if it can describe not just the most likely next diagnosis, but how a patient may evolve over time and how reliable that forecast is. Most deep learning approaches reduce this problem to single-step classification, treating cognitively normal, mild cognitive impairment, and dementia as flat categories while providing limited insight into how uncertainty accumulates across future visits. We propose a probabilistic framework that combines ordinal diagnosis prediction, multi-horizon trajectory generation, and decomposed uncertainty estimation. A Temporal Fusion Transformer encoder is adapted with a CORAL ordinal output layer, asymmetric loss weighting, and converter oversampling to respect disease-stage ordering and improve sensitivity to MCI-to-dementia transitions. Conditioned on the learned patient-context representation, an autoregressive Mixture Density Network generates five-year probabilistic trajectories for diagnosis state, CDR Sum of Boxes, MMSE orientation, and hippocampal volume. On ADNI, the model outperforms linear, recurrent, and transformer baselines for next-visit diagnosis prediction, with the strongest gains on MCI-versus-dementia discrimination. Generated trajectories achieve near-nominal 90% credible interval coverage, widening uncertainty across the forecast horizon, and biomarker dynamics consistent with expected Alzheimer's disease progression. We further separate aleatoric from epistemic uncertainty using analytic mixture variance and a five-member bootstrap ensemble, which provides the strongest encoder diversity and output-level epistemic signal. Epistemic uncertainty is higher for rare progression archetypes, MCI and dementia patients, and under external evaluation on OASIS-3, where it increases alongside prediction error.

  • 3 authors
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Jun 22

Internal Consistency and Self-Feedback in Large Language Models: A Survey

Large language models (LLMs) are expected to respond accurately but often exhibit deficient reasoning or generate hallucinatory content. To address these, studies prefixed with ``Self-'' such as Self-Consistency, Self-Improve, and Self-Refine have been initiated. They share a commonality: involving LLMs evaluating and updating itself to mitigate the issues. Nonetheless, these efforts lack a unified perspective on summarization, as existing surveys predominantly focus on categorization without examining the motivations behind these works. In this paper, we summarize a theoretical framework, termed Internal Consistency, which offers unified explanations for phenomena such as the lack of reasoning and the presence of hallucinations. Internal Consistency assesses the coherence among LLMs' latent layer, decoding layer, and response layer based on sampling methodologies. Expanding upon the Internal Consistency framework, we introduce a streamlined yet effective theoretical framework capable of mining Internal Consistency, named Self-Feedback. The Self-Feedback framework consists of two modules: Self-Evaluation and Self-Update. This framework has been employed in numerous studies. We systematically classify these studies by tasks and lines of work; summarize relevant evaluation methods and benchmarks; and delve into the concern, ``Does Self-Feedback Really Work?'' We propose several critical viewpoints, including the ``Hourglass Evolution of Internal Consistency'', ``Consistency Is (Almost) Correctness'' hypothesis, and ``The Paradox of Latent and Explicit Reasoning''. Furthermore, we outline promising directions for future research. We have open-sourced the experimental code, reference list, and statistical data, available at https://github.com/IAAR-Shanghai/ICSFSurvey.

  • 9 authors
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Jul 19, 2024 9

Self-Generated Feedback Destabilizes Test-Time Training: A Causal Decomposition of Long-Horizon Adaptation

Test-time training (TTT) lets a model store information in its weights during inference. When the model learns from its own output, however, each update also changes the model that generates the next training example. Across 128K-token streams, retaining generated-text updates worsens prediction on independent human-written text with three TTT-E2E model configurations (labeled 125M, 760M, and 3B). The same failure occurs when Adam updates Qwen3-4B's existing weights. The same update mechanisms can improve on real text, so writing itself is not the failure. Three matched comparisons trace the causal pathway. Fixed Generation removes over 98% of the damage at 125M and 760M by using a frozen model to generate training chunks. Recorded Replay separates the loss caused by reading degraded text from the additional loss stored by updating on it. A paired one-update comparison then shows the local conflict: an update predicts its source better but new real text worse. This cost grows after Closed Loop adaptation, with a few trajectories accounting for most large failures. Finally, Settlement evaluates the candidate state on independent real text before commitment. It leaves mean endpoint gaps of 0.07 and -0.02 nats at 125M and 760M while retaining real-text adaptation. These results motivate checking prediction on independent evidence before retaining an update.

LLMs Can Get "Brain Rot"!

We propose and test the LLM Brain Rot Hypothesis: continual exposure to junk web text induces lasting cognitive decline in large language models (LLMs). To causally isolate data quality, we run controlled experiments on real Twitter/X corpora, constructing junk and reversely controlled datasets via two orthogonal operationalizations: M1 (engagement degree) and M2 (semantic quality), with matched token scale and training operations across conditions. Contrary to the control group, continual pre-training of 4 LLMs on the junk dataset causes non-trivial declines (Hedges' g>0.3) on reasoning, long-context understanding, safety, and inflating "dark traits" (e.g., psychopathy, narcissism). The gradual mixtures of junk and control datasets also yield dose-response cognition decay: for example, under M1, ARC-Challenge with Chain Of Thoughts drops 74.9 rightarrow 57.2 and RULER-CWE 84.4 rightarrow 52.3 as junk ratio rises from 0% to 100%. Error forensics reveal several key insights. First, we identify thought-skipping as the primary lesion: models increasingly truncate or skip reasoning chains, explaining most of the error growth. Second, partial but incomplete healing is observed: scaling instruction tuning and clean data pre-training improve the declined cognition yet cannot restore baseline capability, suggesting persistent representational drift rather than format mismatch. Finally, we discover that the popularity, a non-semantic metric, of a tweet is a better indicator of the Brain Rot effect than the length in M1. Together, the results provide significant, multi-perspective evidence that data quality is a causal driver of LLM capability decay, reframing curation for continual pretraining as a training-time safety problem and motivating routine "cognitive health checks" for deployed LLMs.

OOM-RL II: Reality Is an Oracle, Not a Debugger Provenance-Constrained Diagnosis in Continually Evolving Agent-Engineered Systems

Reality may establish that an outcome occurred without identifying which evolving procedure produced it or why. This distinction matters in production ML systems whose code, configuration, and artifacts change while external feedback accumulates. We examine it in a human-directed, agent-engineered quantitative trading system, using oracle to mean an external source of realized outcomes rather than a complete correctness specification. Across one year, the account gained and outperformed a broad market index, while annual alpha was not statistically distinguishable from zero under the main retrospective specification. Retrospectively selected subperiods include adverse relative performance and conditional candidate-level weakness under declared approximate references. Engineering records document changes during the episode, and complete recommendation-to-runtime binding is unavailable. The archive does not establish a common frozen instance or a unique cause. The case motivates an outcome--diagnosis gap: outcome evidence, evaluated-object identity, and causal explanation support distinct claims. We distinguish frozen instances, pre-specified adaptive procedures, and ad-hoc development; organize archive-relative claim identifiability and an evidence hierarchy; and propose a prospective production-binding protocol. An illustrative compatible-history example shows how factual binding can resolve a recommendation's referent without supplying its counterfactual effect. The protocol is proposed rather than prospectively validated. External feedback constrains outcome claims, while provenance and additional identification structure determine the resolution of diagnosis.

  • 2 authors
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Oct 6

Forgetting Is Not a Fix: Path Dependence in Sequential Engram Editing

AI Engram (Kwon et al., 2026) formalizes the four engram criteria of neuroscience as a constrained inverse problem in weight space and solves it closed-form: concept-specific memory traces become linear objects that can be extracted once and combined arithmetically. Appendix F states the Compositional Memory States Hypothesis: edited models live on "a commutative manifold where the integration of A and B reaches a consistent equilibrium regardless of the learning sequence." The evidence base is single and paired edits -- in materials terms, single-cycle tests, in which fatigue accumulation is structurally invisible. Whether the hypothesis holds under sequential load is exactly the "temporal dynamics" question the paper defers to future work. We run that test on the authors' own reference implementation, at their reported best edit strength (TOFU alpha=0.6, a choice favoring the linearity hypothesis), with pre-registered predictions, across three model charges (two vendors, two architecture families). Four findings replicate across all three: (1) zero-shot composition and sequential re-calibrated editing diverge by 61-71% of the edit magnitude; (2) cut order is not interchangeable, and the effect scales with concept overlap -- in one charge the order of cutting two Paris landmarks decides whether an uninvolved third concept survives; (3) the survivors' layer-input covariances -- the method's own sufficient statistics, read as strain gauges -- drift monotonically with every further cut, in every surviving concept, in every charge; (4) erased knowledge partially returns under subsequent unrelated cuts. Appendix F's commutative-manifold hypothesis is thereby falsified for sequential editing; the single-edit results of the original paper are untouched. For unlearning-as-compliance: erasure certified today does not certify the artifact after its next edit.

  • 1 authors
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Jul 5

Sculpting Subspaces: Constrained Full Fine-Tuning in LLMs for Continual Learning

Continual learning in large language models (LLMs) is prone to catastrophic forgetting, where adapting to new tasks significantly degrades performance on previously learned ones. Existing methods typically rely on low-rank, parameter-efficient updates that limit the model's expressivity and introduce additional parameters per task, leading to scalability issues. To address these limitations, we propose a novel continual full fine-tuning approach leveraging adaptive singular value decomposition (SVD). Our method dynamically identifies task-specific low-rank parameter subspaces and constrains updates to be orthogonal to critical directions associated with prior tasks, thus effectively minimizing interference without additional parameter overhead or storing previous task gradients. We evaluate our approach extensively on standard continual learning benchmarks using both encoder-decoder (T5-Large) and decoder-only (LLaMA-2 7B) models, spanning diverse tasks including classification, generation, and reasoning. Empirically, our method achieves state-of-the-art results, up to 7% higher average accuracy than recent baselines like O-LoRA, and notably maintains the model's general linguistic capabilities, instruction-following accuracy, and safety throughout the continual learning process by reducing forgetting to near-negligible levels. Our adaptive SVD framework effectively balances model plasticity and knowledge retention, providing a practical, theoretically grounded, and computationally scalable solution for continual learning scenarios in large language models.

  • 11 authors
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Apr 9, 2025 1

Reformulating Domain Adaptation of Large Language Models as Adapt-Retrieve-Revise

While large language models (LLMs) like GPT-4 have recently demonstrated astonishing zero-shot capabilities in general domain tasks, they often generate content with hallucinations in specific domains such as Chinese law, hindering their application in these areas. This is typically due to the absence of training data that encompasses such a specific domain, preventing GPT-4 from acquiring in-domain knowledge. A pressing challenge is that it's not plausible to continue training LLMs of such scale on in-domain data. This paper introduces a simple and effective domain adaptation framework for GPT-4 by reformulating generation as an adapt-retrieve-revise process. The initial step is to adapt an affordable 7B LLM to the target domain by continuing learning on in-domain data. When solving a task, we leverage the adapted LLM to generate a draft answer given a task query. Then, the draft answer will be used to retrieve supporting evidence candidates from an external in-domain knowledge base. Finally, the draft answer and retrieved evidence are concatenated into a whole prompt to let GPT-4 assess the evidence and revise the draft answer to generate the final answer. Our proposal combines the advantages of the efficiency of adapting a smaller 7B model with the evidence-assessing capability of GPT-4 and effectively prevents GPT-4 from generating hallucinatory content. In the zero-shot setting of four Chinese legal tasks, our method improves accuracy by 33.3\% compared to the direct generation by GPT-4. When compared to two stronger retrieval-based baselines, our method outperforms them by 15.4\% and 23.9\%. Our code will be released

  • 5 authors
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Oct 5, 2023

Geometry Conflict: Explaining and Controlling Forgetting in LLM Continual Post-Training

Continual post-training aims to extend large language models (LLMs) with new knowledge, skills, and behaviors, yet it remains unclear when sequential updates enable capability transfer and when they cause catastrophic forgetting. Existing methods mitigate forgetting through sequential fine-tuning, replay, regularization, or model merging, but offer limited criteria for determining when incorporating new updates is beneficial or harmful. In this work, we study LLM continual post-training through three questions: What drives forgetting? When do sequentially acquired capabilities transfer or interfere? How can compatibility be used to control update integration? We address these questions through task geometry: we represent each post-training task by its parameter update and study the covariance geometry induced by the update. Our central finding is that: forgetting can be considered as a state-relative update-integration failure, it arises when the covariance geometries induced by tasks misalign with the geometry of the evolving model state. Sequential updates transfer when they remain compatible with the model state shaped by previous updates, and interfere when state-relative geometry conflict becomes high. Motivated by this finding, we propose Geometry-Conflict Wasserstein Merging (GCWM), a data-free update-integration method that constructs a shared Wasserstein metric via Gaussian Wasserstein barycenters and uses geometry conflict to gate geometry-aware correction. Across Qwen3 0.6B--14B on domain-continual and capability-continual settings, GCWM consistently outperforms data-free baselines, improving retention and final performance without replay data. These results identify geometry conflict as both an explanatory signal for forgetting and a practical control signal for LLM continual post-training.

MemCut: Every Secret Leaves a Trail in the Long-Term Memory of LLM Agents

Long-term memory has become a crucial component of large language model (LLM) agents, with most research focusing on retrieving relevant information accurately and efficiently. However, a dependable memory system must also forget sensitive user data upon request. To evaluate this capability, we introduce MemCut, a systematic benchmark for user-requested forgetting. Its 456 hand-designed secrets in long-horizon conversations have fully annotated evidence trails to test recovery after deletion, including from messages that never state the secrets directly. We propose two recovery metrics. Native recovery measures reader success through the system's retrieval, whereas residual recovery measures the same reader's success when directly given surviving objects traced to annotated disclosures or evidence. We establish three reference deletion baselines to test how far existing retrievers and write models support forgetting across five memory designs and four LLMs. Disclosure removal reduces native recovery far more than residual recovery. LLM-guided deletion of ten additional turns from twenty retrieval candidates leaves 39-76% residual recovery. Subset sweeps (144 facts, three systems, two models) show that widening the pool at a fixed budget reduces residual recovery more than deleting all original candidates. These sweeps identify candidate coverage as a bottleneck in the reference baselines.

  • 4 authors
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Oct 14

Search over Self-Edit Strategies for LLM Adaptation

Many LLM-based open-ended search systems freeze the foundation model that proposes improvements to existing solutions, which may bottleneck long-run progress. Recent work has explored updating the proposal model at test time [arXiv:2511.23473], but the update strategy is still typically hand-specified. Therefore, this study investigated whether an LLM can use task feedback to decide how it should update its weights. For tractability, we focused on the simpler case where there is only one round of self-improvement, and restricted the update operator to self-supervised next token prediction (NTP), leaving the model freedom in choosing its training data and key NTP hyperparameters. Using the Self-Adapting Language Models (SEAL) [arXiv:2506.10943] framework as a testbed, we relaxed its fixed human template constraint and allowed the model to generate its own self-edit templates, thereby giving it more control over its training data and hyperparameters. Two variants were studied, differing in whether template generation was conditioned on a lightweight archive of past templates. In SEAL's Single-Passage Knowledge Incorporation setting with Qwen3-8B on SQuAD [arXiv:1606.05250], the no-archive variant performed comparably to the weaker "Implications" baseline, while the archive variant outperformed "Implications" and approached the strongest human-designed "Rewrite" baseline without surpassing it. Further analysis of collapse in the model's exploration revealed that a naive archive can confer some short-term robustness but can also accelerate homogenization, suggesting that explicit novelty pressure may be required to consistently advance beyond carefully optimized human strategies. Our code is available at https://github.com/cheongalc/search-self-edit-strategies .

  • 4 authors
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Jan 19

Most LLM Conformity Needs No Speaker: Measuring the Speaker-Free Floor in Peer-Pressure Benchmarks

LLM conformity is often used to describe cases where a model changes a correct answer toward a peer or group response. We show that most of this apparent conformity survives even after the peer is removed. The reason is a confound: standard conformity prompts mix two cues at once, the presence of a speaker and the repeated wrong answer itself. Existing benchmarks vary these cues together, so they cannot tell how much of the revision actually depends on the speaker. We introduce a no-source condition: the same asserted answer with the explicit speaker removed. Across six open-weight LLMs and seven QA and reasoning datasets, this condition alone causes harmful revision in 66.5% of initially correct cases, compared with 10.3% under a plain re-ask. The effect also remains when the repeated answer is paraphrased and when answer options are hidden in an open-ended setting. Source framing mainly modulates this floor: expert-panel framing raises it, while minimal person labels do not reliably raise it. When models flip, they are usually confidently wrong, and simple recalibration does not recover the original answer. Source attribution still matters, but it should be measured as an increment above this speaker-free floor. The methodological lesson is that conformity benchmarks should first measure what remains after the speaker is removed; without this step, benchmarks may mistake repeated text for social influence.

  • 2 authors
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Jul 5

Break Step: Recursive Training Resonates with Replayed Sampling Noise

How fast does a language model degrade when trained on its own outputs? Theory traces it to gradually accumulating errors, while experiments report repeated phrases within ten generations. Under a fixed sampling seed in vLLM, the fast loss of lexical diversity comes from the sampler. When vLLM serves a batch from one seeded sampling configuration, every request receives the same random draws, and a fixed seed replays them every generation. Fine-tuning raises the tokens that won, and the replayed draws let them win by more. Sharing across requests and replay across generations matter only together. Remove either one, by changing the shared seed every generation or by giving each request its own seed that repeats every generation, and the unique-4-gram fraction of two StableLM checkpoints stays near its starting value of about 0.98 through generation 3. Keep both, and the replayed shared seed takes seven checkpoints from five families to between 0.045 and 0.38 by then. Three generations of replay write the favoured phrases into the weights: decoded with one seed per request, the generation-3 weights of the replayed StableLM-2-1.6B chain recover most of their diversity, yet the phrase that filled every sample under the shared seed still opens 46% of them. Without replay, five checkpoints drift slowly, consistent with the gradual accumulation that theory describes, and three turn incoherent though their diversity scores stay high. One peer-reviewed model-collapse pipeline that fine-tunes Gemma-2-27B samples identical prompts under one seeded configuration, and three quarters of the rows it released for one iteration repeat nearly as often as one such batch copies them. A seed per request restores the fresh sample that stability analyses assume.

  • 2 authors
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Sep 28

Continual Learning in Transition

Classical continual learning (CL) has primarily focused on enabling models to update and retain knowledge through parameter-centric mechanisms, e.g., training strategies, architectural designs, and weight adaptation. However, emerging paradigms are reshaping the scope of CL beyond this traditional model adaptation view. For instance, on-policy learning broadens the space of update mechanisms; test-time training extends CL from the training phase to inference; and external harness components such as memory, skill libraries, and interaction protocols extend the evolutionary boundaries of model capabilities far beyond the static parameter space. Collectively, these developments indicate a transition from parameter-centric learning toward system-level adaptation. To characterize this transition, we examine the evolution of continual learning through three dimensions: When, How, and Where learning occurs. The How dimension encompasses off-policy, on-policy, and beyond-gradient optimization mechanics. The When dimension captures evolution across pre-training, post-training, and inference-time stages. The Where dimension delineates updates occurring within internal parameters versus external structural constraints. Anchored by this tri-axial framework, we systematically survey representative methods, trace the ongoing transition of continual learning, and discuss the key challenges, broader implications, and future directions arising from this paradigm shift.

A rubric landscape for evaluating clinical reasoning in large language models: what exists, what is missing, and what needs to be combined

Exam-style accuracy does not establish whether large language models (LLMs) reason well over clinical records. We define clinical reasoning as integrating and updating evidence across time and sources to form, revise and justify a patient's problem representation and a defensible plan. This structured narrative review maps three literatures: medical education assessment instruments, clinical LLM benchmarks published from 2023 onwards, and general-domain methods for evaluating long-form generation. We examine six dimensions: problem representation, temporal synthesis, differential and management reasoning, counterfactual reasoning, calibrated uncertainty, and reasoning faithfulness. Preprints are included and flagged. No single instrument covers all six dimensions. Problem representation and differential or management reasoning are reasonably covered, although reliability varies by instrument and setting. TIMER-Eval targets temporal synthesis, and ER-Reason assesses sequential diagnostic belief updating. Dedicated uncertainty and counterfactual evaluations are emerging, but their applicability to longitudinal free-text reasoning remains limited. Factual completeness is well theorised in general-domain evaluation, with early clinical evidence of important omissions. Faithfulness remains the weakest dimension, with one identified clinical causal-ablation study on multiple-choice questions. Existing tools should be combined through binary rubric items, separate completeness and correctness scores, case-specific importance weighting with non-compensable safety caps, temporal order-consistency checks, and chance-corrected reliability reporting. Further design work is needed for calibrated uncertainty, counterfactual reasoning and faithfulness over longitudinal free-text records. This review provides a design rationale, not a validated instrument.

  • 3 authors
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Sep 30

MMLA: Memory-Mediated Learning Architecture for Predictive Dual-State Adaptation

Memory-Mediated Learning Architecture (MMLA) separates slow base parameters theta, a bounded numerical policy carrier Phi, and a bounded authoritative memory M. Predictive Dual-State Adaptation (PDSA) lets feedback update Phi while one problem remains active and lets a trusted lifecycle atomically commit one typed row or exact NULL. Later reasoning may read both states, but their writers, resets, rollback domains, and ledgers remain distinct. Realized futures supervise values only during training; deployment is causal and future-blind. We give conditional theory and falsifiable contracts for reasoning-time updates, completed-segment consolidation, predictive admission, authoritative memory, and dual-state attribution. Assumptions, counterexamples, capacity and cost ledgers, recovery duties, and identifying experiments are explicit; these are not implementation guarantees. Controlled studies show exact lifecycle execution on 300/300 held-out records for each of three seeds, calibrated retrieval gains over frozen-hidden dense and BM25 baselines, and exact typed anchor-filler transport on 240/240 held-out records per seed. These validate restricted components, not natural-language memory management or complete PDSA. Post-training studies retain positive and negative evidence. Later protocols obtain restricted readout progress, but a nine-trajectory comparison finds that matched latent readout, a full-width bridge, and bridge plus frozen text-teacher alignment all fail continuous-event qualification across both task families. A separately adapted text reference and restoration checks pass. At the September 13, 2026 evidence cutoff, no strict policy-only reasoning-time-training effect, predictive-admission oracle margin, learned future-blind admission policy, or policy-by-memory factorial advantage is established.

  • 2 authors
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Sep 13

CheXGround: Anatomical Region Tokens for Grounded Longitudinal Chest X-ray Interpretation

Recent radiology multi-modal language models have made substantial progress in chest X-ray report generation, visual question answering, and temporal reasoning. While longitudinal chest X-ray interpretation compares sequential examinations to describe change, visual grounding aims to connect clinical language with localized image evidence. Although longitudinal modeling and visual grounding have each advanced radiology language models, how localized visual evidence can support longitudinal interpretation remains under-explored. We introduce CheXGround, a region-grounded longitudinal chest X-ray language model that represents paired studies through corresponding anatomical regions. CheXGround extracts anatomical regions from current and prior radiographs, encodes them as temporally enhanced Region-of-Interest (ROI) tokens, and combines them with global temporal image context during generation. To connect these region tokens with clinical text, we propose Temporal Region--Phrase Alignment, a pretraining objective that aligns temporal anatomical representations with localized report phrases. We evaluate CheXGround on single-study and longitudinal Visual Question Answering (VQA), longitudinal findings generation, temporal grounded VQA, and anatomical grounding. Across these tasks, CheXGround improves clinical language quality, temporal reasoning, and localization accuracy over recent baselines. Our results suggest that organizing longitudinal evidence at the anatomical level is a strong representation for grounded radiology language modeling. Project page: https://adonaydem.github.io/chexground-website

  • 7 authors
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Aug 30

MemoReason: Evaluating the Effect of Parametric Memory on Contextual Reasoning in LLMs

Large Language Models (LLMs) perform well on reasoning benchmarks, but it remains unclear whether this reflects genuine contextual reasoning or reliance on facts memorized in their parameters. We investigate this by distinguishing two possibilities: a broad memorization bias, where familiar content improves reasoning performance, and the Strong Parametric Shortcut Hypothesis, where models skip reasoning entirely and recall stored answers. To test these effects, we introduce MemoReason, a human-curated benchmark that pairs factual reasoning tasks with structurally identical versions where real entities like people, companies, or dates are systematically replaced by ones of the same type. This preserves task structure and specified reasoning operations while varying the familiarity of the context, allowing controlled measurement of how the parametric memory affects reasoning. Our evaluation of recent LLMs reveals consistent and statistically significant performance drops of up to 15.7\% in the fictitious setting, demonstrating a clear memorization bias. However, a targeted analysis of questions failed in the fictitious setting shows that models rarely respond with the corresponding factual answer, indicating that direct parametric shortcuts are not the dominant failure mode. These findings suggest that parametric memory influences reasoning through mechanisms more complex than simple factual recall. MemoReason provides a controlled framework for studying these mechanisms and for extending paired factual-fictitious{} evaluation to broader reasoning settings.

  • 5 authors
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Sep 27

Foresight -- Generative Pretrained Transformer (GPT) for Modelling of Patient Timelines using EHRs

Background: Electronic Health Records hold detailed longitudinal information about each patient's health status and general clinical history, a large portion of which is stored within the unstructured text. Existing approaches focus mostly on structured data and a subset of single-domain outcomes. We explore how temporal modelling of patients from free text and structured data, using deep generative transformers can be used to forecast a wide range of future disorders, substances, procedures or findings. Methods: We present Foresight, a novel transformer-based pipeline that uses named entity recognition and linking tools to convert document text into structured, coded concepts, followed by providing probabilistic forecasts for future medical events such as disorders, substances, procedures and findings. We processed the entire free-text portion from three different hospital datasets totalling 811336 patients covering both physical and mental health. Findings: On tests in two UK hospitals (King's College Hospital, South London and Maudsley) and the US MIMIC-III dataset precision@10 0.68, 0.76 and 0.88 was achieved for forecasting the next disorder in a patient timeline, while precision@10 of 0.80, 0.81 and 0.91 was achieved for forecasting the next biomedical concept. Foresight was also validated on 34 synthetic patient timelines by five clinicians and achieved relevancy of 97% for the top forecasted candidate disorder. As a generative model, it can forecast follow-on biomedical concepts for as many steps as required. Interpretation: Foresight is a general-purpose model for biomedical concept modelling that can be used for real-world risk forecasting, virtual trials and clinical research to study the progression of disorders, simulate interventions and counterfactuals, and educational purposes.

  • 12 authors
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Dec 13, 2022

Voice Interaction With Conversational AI Could Facilitate Thoughtful Reflection and Substantive Revision in Writing

Writing well requires not only expressing ideas but also refining them through revision, a process facilitated by reflection. Prior research suggests that feedback delivered through dialogues, such as those in writing center tutoring sessions, can help writers reflect more thoughtfully on their work compared to static feedback. Recent advancements in multi-modal large language models (LLMs) now offer new possibilities for supporting interactive and expressive voice-based reflection in writing. In particular, we propose that LLM-generated static feedback can be repurposed as conversation starters, allowing writers to seek clarification, request examples, and ask follow-up questions, thereby fostering deeper reflection on their writing. We argue that voice-based interaction can naturally facilitate this conversational exchange, encouraging writers' engagement with higher-order concerns, facilitating iterative refinement of their reflections, and reduce cognitive load compared to text-based interactions. To investigate these effects, we propose a formative study exploring how text vs. voice input influence writers' reflection and subsequent revisions. Findings from this study will inform the design of intelligent and interactive writing tools, offering insights into how voice-based interactions with LLM-powered conversational agents can support reflection and revision.

  • 4 authors
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Apr 10, 2025

Delayed Supervision for Test-Time Language Models

Test-time language models adapt a compact memory while processing the input sequence. This perspective encompasses nonlinear fast-weight learning in LaCT, associative delta-rule updates in DeltaNet, and generalized delta-rule state updates in RWKV-7. Training these models to predict the next token does not explicitly require a fact to remain accessible after many subsequent memory updates. We study delayed supervision for this test-time memory: during post-training, ask a simulator-grounded question only after a long interval of unrelated events, and supervise its answer alongside ordinary next-token prediction. Questions are evaluated on disposable branches, so their answers never enter the continuing event stream. The construction distinguishes retention from revision: a retained fact must remain valid throughout the delay, whereas a revised fact must be answered with its latest value. We evaluate this approach on LaCT-760M and plain DeltaNet-1.3B using TextWorld training trajectories and shared BABILong and RULER evaluation panels, and include a separately reported RWKV-7 comparison. Relative to event-only training, delayed QA improves BABILong by 5.48 percentage points for LaCT and 1.32 points for DeltaNet, and single-needle RULER by 1.45 and 3.27 points, respectively. The RWKV-7 comparison reports gains of 4.60 and 7.00 points on its own panels. These results support delayed semantic supervision as a practical outer training objective for usable test-time memory, while leaving open how much of the benefit derives specifically from delay rather than general question-answering and answer-termination supervision.

  • 2 authors
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Sep 25