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Oct 16

Mirror-Score: Calibrated, Inference-only Scoring Exposes the Limits of Sequence-compatibility Ranking in D-peptide Design

D-peptides combine protease resistance with high target specificity, but computational design of D-peptide binders remains immature. Mirror-Peptidizer introduced an in silico mirror-image screening pipeline using target reflection, backbone generation, and ProteinMPNN sequence design, but its raw ProteinMPNN negative log-likelihood (NLL) ranking was not validated against measured affinities, and only 4 of 9 tested MDM2 designs bound detectably. We introduce Mirror-Score, a calibrated, inference-only scoring framework for heterochiral D-peptide/L-protein complexes, and a public benchmark of 31 crystal complexes across four target families, including 18 with literature-verified affinities. Raw ProteinMPNN NLL is not a valid affinity ranker: its pooled Spearman correlation with affinity is 0.19, and correlations reverse between MDM2/CHIP (+0.62) and gp41 (-0.70). We therefore evaluate Boltz-2 mirror-space cofolding confidence. For the complete viral-entry family (7 structures representing 3 peptides), interface predicted local distance difference test (pLDDT) achieves structure-level leave-one-out Spearman rho = 0.90 (p = 0.006) and correctly orders all three peptides by affinity, whereas NLL fails (structure-level rho = 0.18). Because only three independent chemotypes are represented, this result indicates directional consistency rather than a statistically validated predictor. Cross-family calibration does not transfer at current sample sizes, supporting family-matched calibration as the practical deployment mode. We also specify a prospective design protocol for the antimicrobial-resistance targets LasR and LecB from Pseudomonas aeruginosa, including mirrored structures, ligand-derived hotspot maps, diffusion-model-ready inputs, and Mirror-Score ranking. Code, benchmark data, structures, and analysis scripts are openly available at https://github.com/Jiadalee/Mirror-Score.

  • 1 authors
·
Sep 27

Glance and Focus Reinforcement for Pan-cancer Screening

Pan-cancer screening in large-scale CT scans remains challenging for existing AI methods, primarily due to the difficulty of localizing diverse types of tiny lesions in large CT volumes. The extreme foreground-background imbalance significantly hinders models from focusing on diseased regions, while redundant focus on healthy regions not only decreases the efficiency but also increases false positives. Inspired by radiologists' glance and focus diagnostic strategy, we introduce GF-Screen, a Glance and Focus reinforcement learning framework for pan-cancer screening. GF-Screen employs a Glance model to localize the diseased regions and a Focus model to precisely segment the lesions, where segmentation results of the Focus model are leveraged to reward the Glance model via Reinforcement Learning (RL). Specifically, the Glance model crops a group of sub-volumes from the entire CT volume and learns to select the sub-volumes with lesions for the Focus model to segment. Given that the selecting operation is non-differentiable for segmentation training, we propose to employ the segmentation results to reward the Glance model. To optimize the Glance model, we introduce a novel group relative learning paradigm, which employs group relative comparison to prioritize high-advantage predictions and discard low-advantage predictions within sub-volume groups, not only improving efficiency but also reducing false positives. In this way, for the first time, we effectively extend cutting-edge RL techniques to tackle the specific challenges in pan-cancer screening. Extensive experiments on 16 internal and 7 external datasets across 9 lesion types demonstrated the effectiveness of GF-Screen. Notably, GF-Screen leads the public validation leaderboard of MICCAI FLARE25 pan-cancer challenge, surpassing the FLARE24 champion solution by a large margin (+25.6% DSC and +28.2% NSD).

MirrorWorld: Taming Video Diffusion Models for Mirror Reflection Generation

Recent advances in video diffusion models (VDMs) have enabled high-fidelity video synthesis. However, generating mirror reflections remains challenging because the content within a mirror must remain consistent with the surrounding scene. Existing VDMs are not specifically designed to model scene-to-mirror relationships, which can lead to reflections with incorrect content or inconsistent spatial arrangements. We observe that mirror reflection generation involves two complementary challenges: determining what scene content should be reflected and how the reflected content should be spatially arranged within the mirror region. Motivated by this observation, we propose MirrorWorld, a reflection-aware video inpainting framework that models scene-to-mirror relationships during generation. Specifically, we introduce Semantic Relation Distillation (SRD), which transfers relational information from a frozen visual foundation model to encourage semantic associations between visible scene content and mirror regions. We further propose Geometric Transformation Alignment (GTA), which learns a transformation that guides the spatial arrangement of reflected content. The two components play complementary roles, with SRD modeling what should be reflected and GTA modeling how it should be arranged. To facilitate research on this problem, we construct a benchmark for video mirror reflection generation by repurposing four existing video mirror datasets into a unified reflection reconstruction task. Experimental results show that MirrorWorld achieves improved reflection reconstruction quality over representative image-based reflection generation methods and strong video inpainting baselines.

MIRAGE: Multi-scale Lesion-Informed Representation with Auxiliary Guidance for MRI Contrast Enhancement

Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy. Optimizing only paired pixel fidelity can suppress uncertain lesion enhancement, whereas adversarial or stochastic generative objectives can favor realistic post-contrast appearance without guaranteeing patient-specific lesion fidelity. We introduce MIRAGE, a residual 2D U-Net that combines global reconstruction and perceptual losses with three forms of lesion-aware supervision available only during training: an asymmetric penalty for missed tumor enhancement, multi-scale auxiliary tumor segmentation, and guidance through a frozen post-contrast tumor segmentation nnU-Net. We evaluate the method on 301 cases from the multi-centre MAMA-SYNTH data using eight complementary image-, region-, radiomics-, and segmentation-based metrics. MIRAGE ranks first on six metrics and markedly improves downstream lesion localization over tuned pix2pix, conditional diffusion, and latent bridge-matching baselines. The generative alternatives retain advantages in LPIPS or contrast classification, revealing a clear fidelity-utility trade-off. Leave-one-in and leave-one-out ablations show that the losses are partly redundant for lesion localization but exert distinct effects on appearance, radiomics, and boundary accuracy. These results support task-aware synthesis while also showing that its apparent optimality is conditional on the downstream models and metrics used to define utility.

  • 4 authors
·
Jul 20

Healthy Counterfactual Generation via Diffusion Inpainting for Mammography Classification

False negatives remain a critical limitation of computer-aided diagnosis (CAD) systems for breast cancer screening due to delayed detection and treatment. To address this issue, we propose a counterfactual data augmentation strategy that generates healthy mammograms by "erasing" lesions from anomalous images, thereby enriching the training distribution. We train a Denoising Diffusion Probabilistic Model on BI-RADS 1 (healthy) mammograms and use a RePaint-based sampling strategy to inpaint realistic normal tissue within annotated lesion bounding boxes. The resulting healthy counterfactuals replace annotated lesion regions with realistic healthy tissue while preserving patient-specific anatomical structure, as supported by similarity metrics between real and generated images. Image realism was further assessed by radiologists and found to be consistent with the original dataset quality. We evaluate counterfactual augmentation across four representative classifier architectures: a convolutional neural network (ConvNeXt), a vision transformer (ViT), a vision-language model pre-trained on mammogram-report pairs (Mammo-CLIP) and a multi-scale attention-based multiple-instance learning framework (FPN-MIL). Experiments conducted on the VinDr-Mammo dataset show improvements in sensitivity across all architectures, particularly at 80\% fixed specificity, contributing towards more reliable CAD systems for breast cancer. Code is available at: https://github.com/ines03garcia/diffusion-based-counterfactual-generation.

  • 5 authors
·
Oct 7

MirrorVerse: Pushing Diffusion Models to Realistically Reflect the World

Diffusion models have become central to various image editing tasks, yet they often fail to fully adhere to physical laws, particularly with effects like shadows, reflections, and occlusions. In this work, we address the challenge of generating photorealistic mirror reflections using diffusion-based generative models. Despite extensive training data, existing diffusion models frequently overlook the nuanced details crucial to authentic mirror reflections. Recent approaches have attempted to resolve this by creating synhetic datasets and framing reflection generation as an inpainting task; however, they struggle to generalize across different object orientations and positions relative to the mirror. Our method overcomes these limitations by introducing key augmentations into the synthetic data pipeline: (1) random object positioning, (2) randomized rotations, and (3) grounding of objects, significantly enhancing generalization across poses and placements. To further address spatial relationships and occlusions in scenes with multiple objects, we implement a strategy to pair objects during dataset generation, resulting in a dataset robust enough to handle these complex scenarios. Achieving generalization to real-world scenes remains a challenge, so we introduce a three-stage training curriculum to develop the MirrorFusion 2.0 model to improve real-world performance. We provide extensive qualitative and quantitative evaluations to support our approach. The project page is available at: https://mirror-verse.github.io/.

  • 3 authors
·
Apr 21, 2025

From Synthesis to Removal: Physics-Grounded Reflection Simulation and Diffusion-Based Video Dereflection

Videos captured through glass often contain reflections that degrade visual quality and interfere with downstream vision tasks. Although single-image reflection removal has been extensively studied, video reflection removal remains largely underexplored due to the lack of paired video data, temporally coherent removal models, and dedicated evaluation benchmarks. We present a closed-loop framework that unifies physics-grounded reflection simulation, diffusion-based video dereflection, and benchmark evaluation. Our S2R-Synthesis pipeline generates paired reflected and reflection-free videos by performing physics-grounded augmentation in the structure space and rendering realistic reflected videos with a trained video diffusion renderer; the augmentation models key glass-related effects including roughness-induced blur, thickness-induced ghosting, and reflectance variation. Based on the synthesized data, we introduce S2R-Removal, the first diffusion-based video reflection removal model, which adapts a pretrained video diffusion prior through reflection-aware latent adaptation and one-step pixel-geometric refinement, recovering the clean transmission in a single denoising step. We further build S2R-Bench, the first benchmark for video reflection removal, supporting both full-reference evaluation and real-world human perceptual assessment. Experiments on S2R-Bench and multiple public image benchmarks demonstrate state-of-the-art performance and faster inference than even non-diffusion baselines, and validate the effectiveness of S2R-Synthesis. Project page: https://codingwzp.github.io/VideoDereflection_S2R.

Enhanced Contrastive Learning with Multi-view Longitudinal Data for Chest X-ray Report Generation

Automated radiology report generation offers an effective solution to alleviate radiologists' workload. However, most existing methods focus primarily on single or fixed-view images to model current disease conditions, which limits diagnostic accuracy and overlooks disease progression. Although some approaches utilize longitudinal data to track disease progression, they still rely on single images to analyze current visits. To address these issues, we propose enhanced contrastive learning with Multi-view Longitudinal data to facilitate chest X-ray Report Generation, named MLRG. Specifically, we introduce a multi-view longitudinal contrastive learning method that integrates spatial information from current multi-view images and temporal information from longitudinal data. This method also utilizes the inherent spatiotemporal information of radiology reports to supervise the pre-training of visual and textual representations. Subsequently, we present a tokenized absence encoding technique to flexibly handle missing patient-specific prior knowledge, allowing the model to produce more accurate radiology reports based on available prior knowledge. Extensive experiments on MIMIC-CXR, MIMIC-ABN, and Two-view CXR datasets demonstrate that our MLRG outperforms recent state-of-the-art methods, achieving a 2.3% BLEU-4 improvement on MIMIC-CXR, a 5.5% F1 score improvement on MIMIC-ABN, and a 2.7% F1 RadGraph improvement on Two-view CXR.

  • 7 authors
·
Feb 27, 2025

Development and evaluation of intraoperative ultrasound segmentation with negative image frames and multiple observer labels

When developing deep neural networks for segmenting intraoperative ultrasound images, several practical issues are encountered frequently, such as the presence of ultrasound frames that do not contain regions of interest and the high variance in ground-truth labels. In this study, we evaluate the utility of a pre-screening classification network prior to the segmentation network. Experimental results demonstrate that such a classifier, minimising frame classification errors, was able to directly impact the number of false positive and false negative frames. Importantly, the segmentation accuracy on the classifier-selected frames, that would be segmented, remains comparable to or better than those from standalone segmentation networks. Interestingly, the efficacy of the pre-screening classifier was affected by the sampling methods for training labels from multiple observers, a seemingly independent problem. We show experimentally that a previously proposed approach, combining random sampling and consensus labels, may need to be adapted to perform well in our application. Furthermore, this work aims to share practical experience in developing a machine learning application that assists highly variable interventional imaging for prostate cancer patients, to present robust and reproducible open-source implementations, and to report a set of comprehensive results and analysis comparing these practical, yet important, options in a real-world clinical application.

  • 11 authors
·
Jul 28, 2021

RRTS Dataset: A Benchmark Colonoscopy Dataset from Resource-Limited Settings for Computer-Aided Diagnosis Research

Background and Objective: Colorectal cancer prevention relies on early detection of polyps during colonoscopy. Existing public datasets, such as CVC-ClinicDB and Kvasir-SEG, provide valuable benchmarks but are limited by small sample sizes, curated image selection, or lack of real-world artifacts. There remains a need for datasets that capture the complexity of clinical practice, particularly in resource-constrained settings. Methods: We introduce a dataset, BUET Polyp Dataset (BPD), of colonoscopy images collected using Olympus 170 and Pentax i-Scan series endoscopes under routine clinical conditions. The dataset contains images with corresponding expert-annotated binary masks, reflecting diverse challenges such as motion blur, specular highlights, stool artifacts, blood, and low-light frames. Annotations were manually reviewed by clinical experts to ensure quality. To demonstrate baseline performance, we provide benchmark results for classification using VGG16, ResNet50, and InceptionV3, and for segmentation using UNet variants with VGG16, ResNet34, and InceptionV4 backbones. Results: The dataset comprises 1,288 images with polyps from 164 patients with corresponding ground-truth masks and 1,657 polyp-free images from 31 patients. Benchmarking experiments achieved up to 90.8% accuracy for binary classification (VGG16) and a maximum Dice score of 0.64 with InceptionV4-UNet for segmentation. Performance was lower compared to curated datasets, reflecting the real-world difficulty of images with artifacts and variable quality.

  • 6 authors
·
Nov 10, 2025

Disentanglement and Assessment of Shortcuts in Ophthalmological Retinal Imaging Exams

Diabetic retinopathy (DR) is a leading cause of vision loss in working-age adults. While screening reduces the risk of blindness, traditional imaging is often costly and inaccessible. Artificial intelligence (AI) algorithms present a scalable diagnostic solution, but concerns regarding fairness and generalization persist. This work evaluates the fairness and performance of image-trained models in DR prediction, as well as the impact of disentanglement as a bias mitigation technique, using the diverse mBRSET fundus dataset. Three models, ConvNeXt V2, DINOv2, and Swin V2, were trained on macula images to predict DR and sensitive attributes (SAs) (e.g., age and gender/sex). Fairness was assessed between subgroups of SAs, and disentanglement was applied to reduce bias. All models achieved high DR prediction performance in diagnosing (up to 94% AUROC) and could reasonably predict age and gender/sex (91% and 77% AUROC, respectively). Fairness assessment suggests disparities, such as a 10% AUROC gap between age groups in DINOv2. Disentangling SAs from DR prediction had varying results, depending on the model selected. Disentanglement improved DINOv2 performance (2% AUROC gain), but led to performance drops in ConvNeXt V2 and Swin V2 (7% and 3%, respectively). These findings highlight the complexity of disentangling fine-grained features in fundus imaging and emphasize the importance of fairness in medical imaging AI to ensure equitable and reliable healthcare solutions.

  • 5 authors
·
Jul 13, 2025

ImagiNet: A Multi-Content Dataset for Generalizable Synthetic Image Detection via Contrastive Learning

Generative models, such as diffusion models (DMs), variational autoencoders (VAEs), and generative adversarial networks (GANs), produce images with a level of authenticity that makes them nearly indistinguishable from real photos and artwork. While this capability is beneficial for many industries, the difficulty of identifying synthetic images leaves online media platforms vulnerable to impersonation and misinformation attempts. To support the development of defensive methods, we introduce ImagiNet, a high-resolution and balanced dataset for synthetic image detection, designed to mitigate potential biases in existing resources. It contains 200K examples, spanning four content categories: photos, paintings, faces, and uncategorized. Synthetic images are produced with open-source and proprietary generators, whereas real counterparts of the same content type are collected from public datasets. The structure of ImagiNet allows for a two-track evaluation system: i) classification as real or synthetic and ii) identification of the generative model. To establish a baseline, we train a ResNet-50 model using a self-supervised contrastive objective (SelfCon) for each track. The model demonstrates state-of-the-art performance and high inference speed across established benchmarks, achieving an AUC of up to 0.99 and balanced accuracy ranging from 86% to 95%, even under social network conditions that involve compression and resizing. Our data and code are available at https://github.com/delyan-boychev/imaginet.

  • 2 authors
·
Jul 29, 2024 2

MIRROR: Multi-Modal Pathological Self-Supervised Representation Learning via Modality Alignment and Retention

Histopathology and transcriptomics are fundamental modalities in oncology, encapsulating the morphological and molecular aspects of the disease. Multi-modal self-supervised learning has demonstrated remarkable potential in learning pathological representations by integrating diverse data sources. Conventional multi-modal integration methods primarily emphasize modality alignment, while paying insufficient attention to retaining the modality-specific structures. However, unlike conventional scenarios where multi-modal inputs share highly overlapping features, histopathology and transcriptomics exhibit pronounced heterogeneity, offering orthogonal yet complementary insights. Histopathology provides morphological and spatial context, elucidating tissue architecture and cellular topology, whereas transcriptomics delineates molecular signatures through gene expression patterns. This inherent disparity introduces a major challenge in aligning them while maintaining modality-specific fidelity. To address these challenges, we present MIRROR, a novel multi-modal representation learning method designed to foster both modality alignment and retention. MIRROR employs dedicated encoders to extract comprehensive features for each modality, which is further complemented by a modality alignment module to achieve seamless integration between phenotype patterns and molecular profiles. Furthermore, a modality retention module safeguards unique attributes from each modality, while a style clustering module mitigates redundancy and enhances disease-relevant information by modeling and aligning consistent pathological signatures within a clustering space. Extensive evaluations on TCGA cohorts for cancer subtyping and survival analysis highlight MIRROR's superior performance, demonstrating its effectiveness in constructing comprehensive oncological feature representations and benefiting the cancer diagnosis.

  • 7 authors
·
Mar 1, 2025

Vision-Language Generative Model for View-Specific Chest X-ray Generation

Synthetic medical data generation has opened up new possibilities in the healthcare domain, offering a powerful tool for simulating clinical scenarios, enhancing diagnostic and treatment quality, gaining granular medical knowledge, and accelerating the development of unbiased algorithms. In this context, we present a novel approach called ViewXGen, designed to overcome the limitations of existing methods that rely on general domain pipelines using only radiology reports to generate frontal-view chest X-rays. Our approach takes into consideration the diverse view positions found in the dataset, enabling the generation of chest X-rays with specific views, which marks a significant advancement in the field. To achieve this, we introduce a set of specially designed tokens for each view position, tailoring the generation process to the user's preferences. Furthermore, we leverage multi-view chest X-rays as input, incorporating valuable information from different views within the same study. This integration rectifies potential errors and contributes to faithfully capturing abnormal findings in chest X-ray generation. To validate the effectiveness of our approach, we conducted statistical analyses, evaluating its performance in a clinical efficacy metric on the MIMIC-CXR dataset. Also, human evaluation demonstrates the remarkable capabilities of ViewXGen, particularly in producing realistic view-specific X-rays that closely resemble the original images.

  • 8 authors
·
Feb 23, 2023

Adaptive Multi-head Contrastive Learning

In contrastive learning, two views of an original image, generated by different augmentations, are considered a positive pair, and their similarity is required to be high. Similarly, two views of distinct images form a negative pair, with encouraged low similarity. Typically, a single similarity measure, provided by a lone projection head, evaluates positive and negative sample pairs. However, due to diverse augmentation strategies and varying intra-sample similarity, views from the same image may not always be similar. Additionally, owing to inter-sample similarity, views from different images may be more akin than those from the same image. Consequently, enforcing high similarity for positive pairs and low similarity for negative pairs may be unattainable, and in some cases, such enforcement could detrimentally impact performance. To address this challenge, we propose using multiple projection heads, each producing a distinct set of features. Our pre-training loss function emerges from a solution to the maximum likelihood estimation over head-wise posterior distributions of positive samples given observations. This loss incorporates the similarity measure over positive and negative pairs, each re-weighted by an individual adaptive temperature, regulated to prevent ill solutions. Our approach, Adaptive Multi-Head Contrastive Learning (AMCL), can be applied to and experimentally enhances several popular contrastive learning methods such as SimCLR, MoCo, and Barlow Twins. The improvement remains consistent across various backbones and linear probing epochs, and becomes more significant when employing multiple augmentation methods.

  • 4 authors
·
Oct 9, 2023

Optimizing Breast Cancer Detection in Mammograms: A Comprehensive Study of Transfer Learning, Resolution Reduction, and Multi-View Classification

Mammography, an X-ray-based imaging technique, remains central to the early detection of breast cancer. Recent advances in artificial intelligence have enabled increasingly sophisticated computer-aided diagnostic methods, evolving from patch-based classifiers to whole-image approaches and then to multi-view architectures that jointly analyze complementary projections. Despite this progress, several critical questions remain unanswered. In this study, we systematically investigate these issues by addressing five key research questions: (1) the role of patch classifiers in performance, (2) the transferability of natural-image-trained backbones, (3) the advantages of learn-to-resize over conventional downscaling, (4) the contribution of multi-view integration, and (5) the robustness of findings across varying image quality. Beyond benchmarking, our experiments demonstrate clear performance gains over prior work. For the CBIS-DDSM dataset, we improved single-view AUC from 0.8153 to 0.8343, and multiple-view AUC from 0.8483 to 0.8658. Using a new comparative method, we also observed a 0.0217 AUC increase when extending from single to multiple-view analysis. On the complete VinDr-Mammo dataset, the multiple-view approach further improved results, achieving a 0.0492 AUC increase over single view and reaching 0.8511 AUC overall. These results establish new state-of-the-art benchmarks, providing clear evidence of the advantages of multi-view architectures for mammogram interpretation. Beyond performance, our analysis offers principled insights into model design and transfer learning strategies, contributing to the development of more accurate and reliable breast cancer screening tools. The inference code and trained models are publicly available at https://github.com/dpetrini/multiple-view.

  • 2 authors
·
Mar 25, 2025

Enhancing Environmental Robustness in Few-shot Learning via Conditional Representation Learning

Few-shot learning (FSL) has recently been extensively utilized to overcome the scarcity of training data in domain-specific visual recognition. In real-world scenarios, environmental factors such as complex backgrounds, varying lighting conditions, long-distance shooting, and moving targets often cause test images to exhibit numerous incomplete targets or noise disruptions. However, current research on evaluation datasets and methodologies has largely ignored the concept of "environmental robustness", which refers to maintaining consistent performance in complex and diverse physical environments. This neglect has led to a notable decline in the performance of FSL models during practical testing compared to their training performance. To bridge this gap, we introduce a new real-world multi-domain few-shot learning (RD-FSL) benchmark, which includes four domains and six evaluation datasets. The test images in this benchmark feature various challenging elements, such as camouflaged objects, small targets, and blurriness. Our evaluation experiments reveal that existing methods struggle to utilize training images effectively to generate accurate feature representations for challenging test images. To address this problem, we propose a novel conditional representation learning network (CRLNet) that integrates the interactions between training and testing images as conditional information in their respective representation processes. The main goal is to reduce intra-class variance or enhance inter-class variance at the feature representation level. Finally, comparative experiments reveal that CRLNet surpasses the current state-of-the-art methods, achieving performance improvements ranging from 6.83% to 16.98% across diverse settings and backbones. The source code and dataset are available at https://github.com/guoqianyu-alberta/Conditional-Representation-Learning.

  • 6 authors
·
Feb 3, 2025

BGM: Background Mixup for X-ray Prohibited Items Detection

Current data-driven approaches for X-ray prohibited items detection remain under-explored, particularly in the design of effective data augmentations. Existing natural image augmentations for reflected light imaging neglect the data characteristics of X-ray security images. Moreover, prior X-ray augmentation methods have predominantly focused on foreground prohibited items, overlooking informative background cues. In this paper, we propose Background Mixup (BGM), a background-based augmentation technique tailored for X-ray security imaging domain. Unlike conventional methods, BGM is founded on an in-depth analysis of physical properties including: 1) X-ray Transmission Imagery: Transmitted X-ray pixels represent composite information from multiple materials along the imaging path. 2) Material-based Pseudo-coloring: Pseudo-coloring in X-ray images correlates directly with material properties, aiding in material distinction. Building upon the above insights, BGM mixes background patches across regions on both 1) texture structure and 2) material variation, to benefit models from complicated background cues. This enhances the model's capability to handle domain-specific challenges such as occlusion-induced discriminative imbalance. Importantly, BGM is orthogonal and fully compatible with existing foreground-focused augmentation techniques, enabling joint use to further enhance detection performance. Extensive experiments on multiple X-ray security benchmarks show that BGM consistently surpasses strong baselines, without additional annotations or significant training overhead. This work pioneers the exploration of background-aware augmentation in X-ray prohibited items detection and provides a lightweight, plug-and-play solution with broad applicability.

  • 6 authors
·
Jul 24, 2025

MIRAGE: Towards AI-Generated Image Detection in the Wild

The spreading of AI-generated images (AIGI), driven by advances in generative AI, poses a significant threat to information security and public trust. Existing AIGI detectors, while effective against images in clean laboratory settings, fail to generalize to in-the-wild scenarios. These real-world images are noisy, varying from ``obviously fake" images to realistic ones derived from multiple generative models and further edited for quality control. We address in-the-wild AIGI detection in this paper. We introduce Mirage, a challenging benchmark designed to emulate the complexity of in-the-wild AIGI. Mirage is constructed from two sources: (1) a large corpus of Internet-sourced AIGI verified by human experts, and (2) a synthesized dataset created through the collaboration between multiple expert generators, closely simulating the realistic AIGI in the wild. Building on this benchmark, we propose Mirage-R1, a vision-language model with heuristic-to-analytic reasoning, a reflective reasoning mechanism for AIGI detection. Mirage-R1 is trained in two stages: a supervised-fine-tuning cold start, followed by a reinforcement learning stage. By further adopting an inference-time adaptive thinking strategy, Mirage-R1 is able to provide either a quick judgment or a more robust and accurate conclusion, effectively balancing inference speed and performance. Extensive experiments show that our model leads state-of-the-art detectors by 5% and 10% on Mirage and the public benchmark, respectively. The benchmark and code will be made publicly available.

  • 9 authors
·
Aug 17, 2025

Towards Flexible Interactive Reflection Removal with Human Guidance

Single image reflection removal is inherently ambiguous, as both the reflection and transmission components requiring separation may follow natural image statistics. Existing methods attempt to address the issue by using various types of low-level and physics-based cues as sources of reflection signals. However, these cues are not universally applicable, since they are only observable in specific capture scenarios. This leads to a significant performance drop when test images do not align with their assumptions. In this paper, we aim to explore a novel flexible interactive reflection removal approach that leverages various forms of sparse human guidance, such as points and bounding boxes, as auxiliary high-level prior to achieve robust reflection removal. However, incorporating the raw user guidance naively into the existing reflection removal network does not result in performance gains. To this end, we innovatively transform raw user input into a unified form -- reflection masks using an Interactive Segmentation Foundation Model. Such a design absorbs the quintessence of the foundational segmentation model and flexible human guidance, thereby mitigating the challenges of reflection separations. Furthermore, to fully utilize user guidance and reduce user annotation costs, we design a mask-guided reflection removal network, comprising our proposed self-adaptive prompt block. This block adaptively incorporates user guidance as anchors and refines transmission features via cross-attention mechanisms. Extensive results on real-world images validate that our method demonstrates state-of-the-art performance on various datasets with the help of flexible and sparse user guidance. Our code and dataset will be publicly available here https://github.com/ShawnChenn/FlexibleReflectionRemoval.

  • 7 authors
·
Jun 3, 2024

MetaFormer: High-fidelity Metalens Imaging via Aberration Correcting Transformers

Metalens is an emerging optical system with an irreplaceable merit in that it can be manufactured in ultra-thin and compact sizes, which shows great promise of various applications such as medical imaging and augmented/virtual reality (AR/VR). Despite its advantage in miniaturization, its practicality is constrained by severe aberrations and distortions, which significantly degrade the image quality. Several previous arts have attempted to address different types of aberrations, yet most of them are mainly designed for the traditional bulky lens and not convincing enough to remedy harsh aberrations of the metalens. While there have existed aberration correction methods specifically for metalens, they still fall short of restoration quality. In this work, we propose MetaFormer, an aberration correction framework for metalens-captured images, harnessing Vision Transformers (ViT) that has shown remarkable restoration performance in diverse image restoration tasks. Specifically, we devise a Multiple Adaptive Filters Guidance (MAFG), where multiple Wiener filters enrich the degraded input images with various noise-detail balances, enhancing output restoration quality. In addition, we introduce a Spatial and Transposed self-Attention Fusion (STAF) module, which aggregates features from spatial self-attention and transposed self-attention modules to further ameliorate aberration correction. We conduct extensive experiments, including correcting aberrated images and videos, and clean 3D reconstruction from the degraded images. The proposed method outperforms the previous arts by a significant margin. We further fabricate a metalens and verify the practicality of MetaFormer by restoring the images captured with the manufactured metalens in the wild. Code and pre-trained models are available at https://benhenryl.github.io/MetaFormer

  • 10 authors
·
Dec 5, 2024

FakeMix Augmentation Improves Transparent Object Detection

Detecting transparent objects in natural scenes is challenging due to the low contrast in texture, brightness and colors. Recent deep-learning-based works reveal that it is effective to leverage boundaries for transparent object detection (TOD). However, these methods usually encounter boundary-related imbalance problem, leading to limited generation capability. Detailly, a kind of boundaries in the background, which share the same characteristics with boundaries of transparent objects but have much smaller amounts, usually hurt the performance. To conquer the boundary-related imbalance problem, we propose a novel content-dependent data augmentation method termed FakeMix. Considering collecting these trouble-maker boundaries in the background is hard without corresponding annotations, we elaborately generate them by appending the boundaries of transparent objects from other samples into the current image during training, which adjusts the data space and improves the generalization of the models. Further, we present AdaptiveASPP, an enhanced version of ASPP, that can capture multi-scale and cross-modality features dynamically. Extensive experiments demonstrate that our methods clearly outperform the state-of-the-art methods. We also show that our approach can also transfer well on related tasks, in which the model meets similar troubles, such as mirror detection, glass detection, and camouflaged object detection. Code will be made publicly available.

  • 7 authors
·
Oct 18, 2021

Exploring Specular Reflection Inconsistency for Generalizable Face Forgery Detection

Detecting deepfakes has become increasingly challenging as forgery faces synthesized by AI-generated methods, particularly diffusion models, achieve unprecedented quality and resolution. Existing forgery detection approaches relying on spatial and frequency features demonstrate limited efficacy against high-quality, entirely synthesized forgeries. In this paper, we propose a novel detection method grounded in the observation that facial attributes governed by complex physical laws and multiple parameters are inherently difficult to replicate. Specifically, we focus on illumination, particularly the specular reflection component in the Phong illumination model, which poses the greatest replication challenge due to its parametric complexity and nonlinear formulation. We introduce a fast and accurate face texture estimation method based on Retinex theory to enable precise specular reflection separation. Furthermore, drawing from the mathematical formulation of specular reflection, we posit that forgery evidence manifests not only in the specular reflection itself but also in its relationship with corresponding face texture and direct light. To address this issue, we design the Specular-Reflection-Inconsistency-Network (SRI-Net), incorporating a two-stage cross-attention mechanism to capture these correlations and integrate specular reflection related features with image features for robust forgery detection. Experimental results demonstrate that our method achieves superior performance on both traditional deepfake datasets and generative deepfake datasets, particularly those containing diffusion-generated forgery faces.

  • 5 authors
·
Feb 6

Deep Analog: Open-Set Film Emulation with Reference-Conditioned 3D LUTs

Film emulation reproduces the look of an analog film stock on a new digital photograph. We target its open-set form -- matching any reference film frame from a single example -- with a 3D lookup table (LUT) predicted from that reference. Real-time image enhancement predicts per-image weights over a fixed bank of 3D LUTs and blends them. We show this is a gated mixture of experts and inherits its failure: trained end-to-end against reconstruction, the gate collapses onto a single expert, so a bank of K LUTs delivers the capacity of one. An entropy term, the enhancement-setting analogue of mixture-of-experts load balancing, restores utilization and recovers about 1 dB PSNR. The deeper constraint survives: a fixed LUT basis is closed-set, freezing the achievable looks at training time. We therefore discard the basis and predict a single 3D LUT as a residual from a reference image (StyleLUTNet), trained by self-supervision on procedurally generated color transforms. The conditional design removes the gate and generalizes open-set to unseen film stocks without paired data or retraining. Around this color backbone we build Deep Analog, a film-emulation pipeline that adds histogram-based tone matching and a physics-informed optical renderer -- multi-scale grain and per-channel halation driven by parameters an inverse network regresses from the reference. On 350 self-supervised pairs the color stage reaches 22.05 dB PSNR / 0.925 SSIM and the full pipeline 21.72 dB / 0.923; the color path runs in 5.2 ms at 1080p (192 FPS) and exports a portable .cube LUT for standard editing tools. A second degeneracy in conditional LUT training -- residual-scale collapse -- shares the root cause and yields a general principle: auxiliary regularization must stay subordinate to reconstruction.

  • 1 authors
·
Aug 9

Self-supervised Learning to Bring Dual Reversed Rolling Shutter Images Alive

Modern consumer cameras usually employ the rolling shutter (RS) mechanism, where images are captured by scanning scenes row-by-row, yielding RS distortions for dynamic scenes. To correct RS distortions, existing methods adopt a fully supervised learning manner, where high framerate global shutter (GS) images should be collected as ground-truth supervision. In this paper, we propose a Self-supervised learning framework for Dual reversed RS distortions Correction (SelfDRSC), where a DRSC network can be learned to generate a high framerate GS video only based on dual RS images with reversed distortions. In particular, a bidirectional distortion warping module is proposed for reconstructing dual reversed RS images, and then a self-supervised loss can be deployed to train DRSC network by enhancing the cycle consistency between input and reconstructed dual reversed RS images. Besides start and end RS scanning time, GS images at arbitrary intermediate scanning time can also be supervised in SelfDRSC, thus enabling the learned DRSC network to generate a high framerate GS video. Moreover, a simple yet effective self-distillation strategy is introduced in self-supervised loss for mitigating boundary artifacts in generated GS images. On synthetic dataset, SelfDRSC achieves better or comparable quantitative metrics in comparison to state-of-the-art methods trained in the full supervision manner. On real-world RS cases, our SelfDRSC can produce high framerate GS videos with finer correction textures and better temporary consistency. The source code and trained models are made publicly available at https://github.com/shangwei5/SelfDRSC.

  • 6 authors
·
May 31, 2023

PraNet: Parallel Reverse Attention Network for Polyp Segmentation

Colonoscopy is an effective technique for detecting colorectal polyps, which are highly related to colorectal cancer. In clinical practice, segmenting polyps from colonoscopy images is of great importance since it provides valuable information for diagnosis and surgery. However, accurate polyp segmentation is a challenging task, for two major reasons: (i) the same type of polyps has a diversity of size, color and texture; and (ii) the boundary between a polyp and its surrounding mucosa is not sharp. To address these challenges, we propose a parallel reverse attention network (PraNet) for accurate polyp segmentation in colonoscopy images. Specifically, we first aggregate the features in high-level layers using a parallel partial decoder (PPD). Based on the combined feature, we then generate a global map as the initial guidance area for the following components. In addition, we mine the boundary cues using a reverse attention (RA) module, which is able to establish the relationship between areas and boundary cues. Thanks to the recurrent cooperation mechanism between areas and boundaries, our PraNet is capable of calibrating any misaligned predictions, improving the segmentation accuracy. Quantitative and qualitative evaluations on five challenging datasets across six metrics show that our PraNet improves the segmentation accuracy significantly, and presents a number of advantages in terms of generalizability, and real-time segmentation efficiency.

  • 7 authors
·
Jun 13, 2020

A Comprehensive Study of GPT-4V's Multimodal Capabilities in Medical Imaging

This paper presents a comprehensive evaluation of GPT-4V's capabilities across diverse medical imaging tasks, including Radiology Report Generation, Medical Visual Question Answering (VQA), and Visual Grounding. While prior efforts have explored GPT-4V's performance in medical image analysis, to the best of our knowledge, our study represents the first quantitative evaluation on publicly available benchmarks. Our findings highlight GPT-4V's potential in generating descriptive reports for chest X-ray images, particularly when guided by well-structured prompts. Meanwhile, its performance on the MIMIC-CXR dataset benchmark reveals areas for improvement in certain evaluation metrics, such as CIDEr. In the domain of Medical VQA, GPT-4V demonstrates proficiency in distinguishing between question types but falls short of the VQA-RAD benchmark in terms of accuracy. Furthermore, our analysis finds the limitations of conventional evaluation metrics like the BLEU scores, advocating for the development of more semantically robust assessment methods. In the field of Visual Grounding, GPT-4V exhibits preliminary promise in recognizing bounding boxes, but its precision is lacking, especially in identifying specific medical organs and signs. Our evaluation underscores the significant potential of GPT-4V in the medical imaging domain, while also emphasizing the need for targeted refinements to fully unlock its capabilities.

  • 10 authors
·
Oct 31, 2023

ISP-AD: A Large-Scale Real-World Dataset for Advancing Industrial Anomaly Detection with Synthetic and Real Defects

Automatic visual inspection using machine learning plays a key role in achieving zero-defect policies in industry. Research on anomaly detection is constrained by the availability of datasets that capture complex defect appearances and imperfect imaging conditions, which are typical of production processes. Recent benchmarks indicate that most publicly available datasets are biased towards optimal imaging conditions, leading to an overestimation of their applicability in real-world industrial scenarios. To address this gap, we introduce the Industrial Screen Printing Anomaly Detection Dataset (ISP-AD). It presents challenging small and weakly contrasted surface defects embedded within structured patterns exhibiting high permitted design variability. To the best of our knowledge, it is the largest publicly available industrial dataset to date, including both synthetic and real defects collected directly from the factory floor. Beyond benchmarking recent unsupervised anomaly detection methods, experiments on a mixed supervised training strategy, incorporating both synthesized and real defects, were conducted. Experiments show that even a small amount of injected, weakly labeled real defects improves generalization. Furthermore, starting from training on purely synthetic defects, emerging real defective samples can be efficiently integrated into subsequent scalable training. Overall, our findings indicate that model-free synthetic defects can provide a cold-start baseline, whereas a small number of injected real defects refine the decision boundary for previously unseen defect characteristics. The presented unsupervised and supervised dataset splits are designed to emphasize research on unsupervised, self-supervised, and supervised approaches, enhancing their applicability to industrial settings.

  • 2 authors
·
Sep 2

Redefining Generalization in Visual Domains: A Two-Axis Framework for Fake Image Detection with FusionDetect

The rapid development of generative models has made it increasingly crucial to develop detectors that can reliably detect synthetic images. Although most of the work has now focused on cross-generator generalization, we argue that this viewpoint is too limited. Detecting synthetic images involves another equally important challenge: generalization across visual domains. To bridge this gap,we present the OmniGen Benchmark. This comprehensive evaluation dataset incorporates 12 state-of-the-art generators, providing a more realistic way of evaluating detector performance under realistic conditions. In addition, we introduce a new method, FusionDetect, aimed at addressing both vectors of generalization. FusionDetect draws on the benefits of two frozen foundation models: CLIP & Dinov2. By deriving features from both complementary models,we develop a cohesive feature space that naturally adapts to changes in both thecontent and design of the generator. Our extensive experiments demonstrate that FusionDetect delivers not only a new state-of-the-art, which is 3.87% more accurate than its closest competitor and 6.13% more precise on average on established benchmarks, but also achieves a 4.48% increase in accuracy on OmniGen,along with exceptional robustness to common image perturbations. We introduce not only a top-performing detector, but also a new benchmark and framework for furthering universal AI image detection. The code and dataset are available at http://github.com/amir-aman/FusionDetect

  • 4 authors
·
Oct 7, 2025

Enhancing Pathological VLMs with Cross-scale Reasoning

Pathological images are inherently multi-scale, requiring pathologists to integrate evidence from global tissue architecture at low magnification to cellular morphology at higher magnification for accurate diagnosis. While existing pathological datasets for vision-language models (VLMs) include various scales, they often lack explicit cross-scale reasoning objectives. This limitation prevents VLMs from capturing essential cross-scale representations and learning evidence-based reasoning. To bridge this gap, we introduce the first cross-scale training and evaluation paradigm that formulates pathology interpretation as multi-magnification reasoning. However, creating such a task reveals a critical challenge: multi-image visual question answering (VQA) is prone to text-only shortcuts, which allow models to guess answers using magnification-dependent artifacts rather than visual evidence. To address this, we propose a leakage-aware curation pipeline that combines adversarial text-only screening with constraint-guided question design. Using this pipeline, we construct Scale-VQA, a high-quality benchmark with 4,685 multiple-choice questions grounded in 2,537 pathology images across multiple magnification levels. Finally, we present ScaleReasoner-R1, a model trained via reinforcement learning to optimize performance on cross-scale VQA tasks. ScaleReasoner-R1 achieves state-of-the-art performance on our cross-scale reasoning benchmark and generalizes to SOTA performance on established single-scale benchmarks. Findings suggest that even the limited cross-scale supervision can significantly improve pathological understanding. Code is available at https://github.com/iMVR-PL/ScaleReasoner-R1.

  • 8 authors
·
Jun 23

Hate in Plain Sight: On the Risks of Moderating AI-Generated Hateful Illusions

Recent advances in text-to-image diffusion models have enabled the creation of a new form of digital art: optical illusions--visual tricks that create different perceptions of reality. However, adversaries may misuse such techniques to generate hateful illusions, which embed specific hate messages into harmless scenes and disseminate them across web communities. In this work, we take the first step toward investigating the risks of scalable hateful illusion generation and the potential for bypassing current content moderation models. Specifically, we generate 1,860 optical illusions using Stable Diffusion and ControlNet, conditioned on 62 hate messages. Of these, 1,571 are hateful illusions that successfully embed hate messages, either overtly or subtly, forming the Hateful Illusion dataset. Using this dataset, we evaluate the performance of six moderation classifiers and nine vision language models (VLMs) in identifying hateful illusions. Experimental results reveal significant vulnerabilities in existing moderation models: the detection accuracy falls below 0.245 for moderation classifiers and below 0.102 for VLMs. We further identify a critical limitation in their vision encoders, which mainly focus on surface-level image details while overlooking the secondary layer of information, i.e., hidden messages. To address this risk, we explore preliminary mitigation measures and identify the most effective approaches from the perspectives of image transformations and training-level strategies.

  • 6 authors
·
Jul 30, 2025

UMat: Uncertainty-Aware Single Image High Resolution Material Capture

We propose a learning-based method to recover normals, specularity, and roughness from a single diffuse image of a material, using microgeometry appearance as our primary cue. Previous methods that work on single images tend to produce over-smooth outputs with artifacts, operate at limited resolution, or train one model per class with little room for generalization. Previous methods that work on single images tend to produce over-smooth outputs with artifacts, operate at limited resolution, or train one model per class with little room for generalization. In contrast, in this work, we propose a novel capture approach that leverages a generative network with attention and a U-Net discriminator, which shows outstanding performance integrating global information at reduced computational complexity. We showcase the performance of our method with a real dataset of digitized textile materials and show that a commodity flatbed scanner can produce the type of diffuse illumination required as input to our method. Additionally, because the problem might be illposed -more than a single diffuse image might be needed to disambiguate the specular reflection- or because the training dataset is not representative enough of the real distribution, we propose a novel framework to quantify the model's confidence about its prediction at test time. Our method is the first one to deal with the problem of modeling uncertainty in material digitization, increasing the trustworthiness of the process and enabling more intelligent strategies for dataset creation, as we demonstrate with an active learning experiment.

  • 4 authors
·
May 25, 2023

High-Resolution Virtual Try-On with Misalignment and Occlusion-Handled Conditions

Image-based virtual try-on aims to synthesize an image of a person wearing a given clothing item. To solve the task, the existing methods warp the clothing item to fit the person's body and generate the segmentation map of the person wearing the item before fusing the item with the person. However, when the warping and the segmentation generation stages operate individually without information exchange, the misalignment between the warped clothes and the segmentation map occurs, which leads to the artifacts in the final image. The information disconnection also causes excessive warping near the clothing regions occluded by the body parts, so-called pixel-squeezing artifacts. To settle the issues, we propose a novel try-on condition generator as a unified module of the two stages (i.e., warping and segmentation generation stages). A newly proposed feature fusion block in the condition generator implements the information exchange, and the condition generator does not create any misalignment or pixel-squeezing artifacts. We also introduce discriminator rejection that filters out the incorrect segmentation map predictions and assures the performance of virtual try-on frameworks. Experiments on a high-resolution dataset demonstrate that our model successfully handles the misalignment and occlusion, and significantly outperforms the baselines. Code is available at https://github.com/sangyun884/HR-VITON.

  • 5 authors
·
Jun 28, 2022

A Lightweight Face Quality Assessment Framework to Improve Face Verification Performance in Real-Time Screening Applications

Face image quality plays a critical role in determining the accuracy and reliability of face verification systems, particularly in real-time screening applications such as surveillance, identity verification, and access control. Low-quality face images, often caused by factors such as motion blur, poor lighting conditions, occlusions, and extreme pose variations, significantly degrade the performance of face recognition models, leading to higher false rejection and false acceptance rates. In this work, we propose a lightweight yet effective framework for automatic face quality assessment, which aims to pre-filter low-quality face images before they are passed to the verification pipeline. Our approach utilises normalised facial landmarks in conjunction with a Random Forest Regression classifier to assess image quality, achieving an accuracy of 96.67%. By integrating this quality assessment module into the face verification process, we observe a substantial improvement in performance, including a comfortable 99.7% reduction in the false rejection rate and enhanced cosine similarity scores when paired with the ArcFace face verification model. To validate our approach, we have conducted experiments on a real-world dataset collected comprising over 600 subjects captured from CCTV footage in unconstrained environments within Dubai Police. Our results demonstrate that the proposed framework effectively mitigates the impact of poor-quality face images, outperforming existing face quality assessment techniques while maintaining computational efficiency. Moreover, the framework specifically addresses two critical challenges in real-time screening: variations in face resolution and pose deviations, both of which are prevalent in practical surveillance scenarios.

  • 8 authors
·
Jul 21, 2025

QTSeg: A Query Token-Based Dual-Mix Attention Framework with Multi-Level Feature Distribution for Medical Image Segmentation

Medical image segmentation plays a crucial role in assisting healthcare professionals with accurate diagnoses and enabling automated diagnostic processes. Traditional convolutional neural networks (CNNs) often struggle with capturing long-range dependencies, while transformer-based architectures, despite their effectiveness, come with increased computational complexity. Recent efforts have focused on combining CNNs and transformers to balance performance and efficiency, but existing approaches still face challenges in achieving high segmentation accuracy while maintaining low computational costs. Furthermore, many methods underutilize the CNN encoder's capability to capture local spatial information, concentrating primarily on mitigating long-range dependency issues. To address these limitations, we propose QTSeg, a novel architecture for medical image segmentation that effectively integrates local and global information. QTSeg features a dual-mix attention decoder designed to enhance segmentation performance through: (1) a cross-attention mechanism for improved feature alignment, (2) a spatial attention module to capture long-range dependencies, and (3) a channel attention block to learn inter-channel relationships. Additionally, we introduce a multi-level feature distribution module, which adaptively balances feature propagation between the encoder and decoder, further boosting performance. Extensive experiments on five publicly available datasets covering diverse segmentation tasks, including lesion, polyp, breast cancer, cell, and retinal vessel segmentation, demonstrate that QTSeg outperforms state-of-the-art methods across multiple evaluation metrics while maintaining lower computational costs. Our implementation can be found at: https://github.com/tpnam0901/QTSeg (v1.0.0)

  • 5 authors
·
Dec 22, 2024

Illicit object detection in X-ray imaging using deep learning techniques: A comparative evaluation

Automated X-ray inspection is crucial for efficient and unobtrusive security screening in various public settings. However, challenges such as object occlusion, variations in the physical properties of items, diversity in X-ray scanning devices, and limited training data hinder accurate and reliable detection of illicit items. Despite the large body of research in the field, reported experimental evaluations are often incomplete, with frequently conflicting outcomes. To shed light on the research landscape and facilitate further research, a systematic, detailed, and thorough comparative evaluation of recent Deep Learning (DL)-based methods for X-ray object detection is conducted. For this, a comprehensive evaluation framework is developed, composed of: a) Six recent, large-scale, and widely used public datasets for X-ray illicit item detection (OPIXray, CLCXray, SIXray, EDS, HiXray, and PIDray), b) Ten different state-of-the-art object detection schemes covering all main categories in the literature, including generic Convolutional Neural Network (CNN), custom CNN, generic transformer, and hybrid CNN-transformer architectures, and c) Various detection (mAP50 and mAP50:95) and time/computational-complexity (inference time (ms), parameter size (M), and computational load (GFLOPS)) metrics. A thorough analysis of the results leads to critical observations and insights, emphasizing key aspects such as: a) Overall behavior of the object detection schemes, b) Object-level detection performance, c) Dataset-specific observations, and d) Time efficiency and computational complexity analysis. To support reproducibility of the reported experimental results, the evaluation code and model weights are made publicly available at https://github.com/jgenc/xray-comparative-evaluation.

  • 8 authors
·
Jul 23, 2025

ScreenMark: Watermarking Arbitrary Visual Content on Screen

Digital watermarking has shown its effectiveness in protecting multimedia content. However, existing watermarking is predominantly tailored for specific media types, rendering them less effective for the protection of content displayed on computer screens, which is often multi-modal and dynamic. Visual Screen Content (VSC), is particularly susceptible to theft and leakage through screenshots, a vulnerability that current watermarking methods fail to adequately address.To address these challenges, we propose ScreenMark, a robust and practical watermarking method designed specifically for arbitrary VSC protection. ScreenMark utilizes a three-stage progressive watermarking framework. Initially, inspired by diffusion principles, we initialize the mutual transformation between regular watermark information and irregular watermark patterns. Subsequently, these patterns are integrated with screen content using a pre-multiplication alpha blending technique, supported by a pre-trained screen decoder for accurate watermark retrieval. The progressively complex distorter enhances the robustness of the watermark in real-world screenshot scenarios. Finally, the model undergoes fine-tuning guided by a joint-level distorter to ensure optimal performance. To validate the effectiveness of ScreenMark, we compiled a dataset comprising 100,000 screenshots from various devices and resolutions. Extensive experiments on different datasets confirm the superior robustness, imperceptibility, and practical applicability of the method.

  • 5 authors
·
Sep 5, 2024

A New Dataset and Performance Benchmark for Real-time Spacecraft Segmentation in Onboard Flight Computers

Spacecraft deployed in outer space are routinely subjected to various forms of damage due to exposure to hazardous environments. In addition, there are significant risks to the subsequent process of in-space repairs through human extravehicular activity or robotic manipulation, incurring substantial operational costs. Recent developments in image segmentation could enable the development of reliable and cost-effective autonomous inspection systems. While these models often require large amounts of training data to achieve satisfactory results, publicly available annotated spacecraft segmentation data are very scarce. Here, we present a new dataset of nearly 64k annotated spacecraft images that was created using real spacecraft models, superimposed on a mixture of real and synthetic backgrounds generated using NASA's TTALOS pipeline. To mimic camera distortions and noise in real-world image acquisition, we also added different types of noise and distortion to the images. Finally, we finetuned YOLOv8 and YOLOv11 segmentation models to generate performance benchmarks for the dataset under well-defined hardware and inference time constraints to mimic real-world image segmentation challenges for real-time onboard applications in space on NASA's inspector spacecraft. The resulting models, when tested under these constraints, achieved a Dice score of 0.92, Hausdorff distance of 0.69, and an inference time of about 0.5 second. The dataset and models for performance benchmark are available at https://github.com/RiceD2KLab/SWiM.

  • 9 authors
·
Jul 14, 2025

DreamVVT: Mastering Realistic Video Virtual Try-On in the Wild via a Stage-Wise Diffusion Transformer Framework

Video virtual try-on (VVT) technology has garnered considerable academic interest owing to its promising applications in e-commerce advertising and entertainment. However, most existing end-to-end methods rely heavily on scarce paired garment-centric datasets and fail to effectively leverage priors of advanced visual models and test-time inputs, making it challenging to accurately preserve fine-grained garment details and maintain temporal consistency in unconstrained scenarios. To address these challenges, we propose DreamVVT, a carefully designed two-stage framework built upon Diffusion Transformers (DiTs), which is inherently capable of leveraging diverse unpaired human-centric data to enhance adaptability in real-world scenarios. To further leverage prior knowledge from pretrained models and test-time inputs, in the first stage, we sample representative frames from the input video and utilize a multi-frame try-on model integrated with a vision-language model (VLM), to synthesize high-fidelity and semantically consistent keyframe try-on images. These images serve as complementary appearance guidance for subsequent video generation. In the second stage, skeleton maps together with fine-grained motion and appearance descriptions are extracted from the input content, and these along with the keyframe try-on images are then fed into a pretrained video generation model enhanced with LoRA adapters. This ensures long-term temporal coherence for unseen regions and enables highly plausible dynamic motions. Extensive quantitative and qualitative experiments demonstrate that DreamVVT surpasses existing methods in preserving detailed garment content and temporal stability in real-world scenarios. Our project page https://virtu-lab.github.io/

  • 10 authors
·
Aug 4, 2025 2

Adaptively Weighted Data Augmentation Consistency Regularization for Robust Optimization under Concept Shift

Concept shift is a prevailing problem in natural tasks like medical image segmentation where samples usually come from different subpopulations with variant correlations between features and labels. One common type of concept shift in medical image segmentation is the "information imbalance" between label-sparse samples with few (if any) segmentation labels and label-dense samples with plentiful labeled pixels. Existing distributionally robust algorithms have focused on adaptively truncating/down-weighting the "less informative" (i.e., label-sparse in our context) samples. To exploit data features of label-sparse samples more efficiently, we propose an adaptively weighted online optimization algorithm -- AdaWAC -- to incorporate data augmentation consistency regularization in sample reweighting. Our method introduces a set of trainable weights to balance the supervised loss and unsupervised consistency regularization of each sample separately. At the saddle point of the underlying objective, the weights assign label-dense samples to the supervised loss and label-sparse samples to the unsupervised consistency regularization. We provide a convergence guarantee by recasting the optimization as online mirror descent on a saddle point problem. Our empirical results demonstrate that AdaWAC not only enhances the segmentation performance and sample efficiency but also improves the robustness to concept shift on various medical image segmentation tasks with different UNet-style backbones.

  • 3 authors
·
Oct 4, 2022

Pose as Clinical Prior: Learning Dual Representations for Scoliosis Screening

Recent AI-based scoliosis screening methods primarily rely on large-scale silhouette datasets, often neglecting clinically relevant postural asymmetries-key indicators in traditional screening. In contrast, pose data provide an intuitive skeletal representation, enhancing clinical interpretability across various medical applications. However, pose-based scoliosis screening remains underexplored due to two main challenges: (1) the scarcity of large-scale, annotated pose datasets; and (2) the discrete and noise-sensitive nature of raw pose coordinates, which hinders the modeling of subtle asymmetries. To address these limitations, we introduce Scoliosis1K-Pose, a 2D human pose annotation set that extends the original Scoliosis1K dataset, comprising 447,900 frames of 2D keypoints from 1,050 adolescents. Building on this dataset, we introduce the Dual Representation Framework (DRF), which integrates a continuous skeleton map to preserve spatial structure with a discrete Postural Asymmetry Vector (PAV) that encodes clinically relevant asymmetry descriptors. A novel PAV-Guided Attention (PGA) module further uses the PAV as clinical prior to direct feature extraction from the skeleton map, focusing on clinically meaningful asymmetries. Extensive experiments demonstrate that DRF achieves state-of-the-art performance. Visualizations further confirm that the model leverages clinical asymmetry cues to guide feature extraction and promote synergy between its dual representations. The dataset and code are publicly available at https://zhouzi180.github.io/Scoliosis1K/.

  • 6 authors
·
Aug 31, 2025

C3S3: Complementary Competition and Contrastive Selection for Semi-Supervised Medical Image Segmentation

For the immanent challenge of insufficiently annotated samples in the medical field, semi-supervised medical image segmentation (SSMIS) offers a promising solution. Despite achieving impressive results in delineating primary target areas, most current methodologies struggle to precisely capture the subtle details of boundaries. This deficiency often leads to significant diagnostic inaccuracies. To tackle this issue, we introduce C3S3, a novel semi-supervised segmentation model that synergistically integrates complementary competition and contrastive selection. This design significantly sharpens boundary delineation and enhances overall precision. Specifically, we develop an Outcome-Driven Contrastive Learning module dedicated to refining boundary localization. Additionally, we incorporate a Dynamic Complementary Competition module that leverages two high-performing sub-networks to generate pseudo-labels, thereby further improving segmentation quality. The proposed C3S3 undergoes rigorous validation on two publicly accessible datasets, encompassing the practices of both MRI and CT scans. The results demonstrate that our method achieves superior performance compared to previous cutting-edge competitors. Especially, on the 95HD and ASD metrics, our approach achieves a notable improvement of at least 6%, highlighting the significant advancements. The code is available at https://github.com/Y-TARL/C3S3.

  • 5 authors
·
Jun 8, 2025

Lesion-aware network for diabetic retinopathy diagnosis

Deep learning brought boosts to auto diabetic retinopathy (DR) diagnosis, thus, greatly helping ophthalmologists for early disease detection, which contributes to preventing disease deterioration that may eventually lead to blindness. It has been proved that convolutional neural network (CNN)-aided lesion identifying or segmentation benefits auto DR screening. The key to fine-grained lesion tasks mainly lies in: (1) extracting features being both sensitive to tiny lesions and robust against DR-irrelevant interference, and (2) exploiting and re-using encoded information to restore lesion locations under extremely imbalanced data distribution. To this end, we propose a CNN-based DR diagnosis network with attention mechanism involved, termed lesion-aware network, to better capture lesion information from imbalanced data. Specifically, we design the lesion-aware module (LAM) to capture noise-like lesion areas across deeper layers, and the feature-preserve module (FPM) to assist shallow-to-deep feature fusion. Afterward, the proposed lesion-aware network (LANet) is constructed by embedding the LAM and FPM into the CNN decoders for DR-related information utilization. The proposed LANet is then further extended to a DR screening network by adding a classification layer. Through experiments on three public fundus datasets with pixel-level annotations, our method outperforms the mainstream methods with an area under curve of 0.967 in DR screening, and increases the overall average precision by 7.6%, 2.1%, and 1.2% in lesion segmentation on three datasets. Besides, the ablation study validates the effectiveness of the proposed sub-modules.

  • 5 authors
·
Aug 13, 2024

Reflect-R1: Evidence-Driven Reflection for Self-Correction in Long Video Understanding

Current multimodal reflection mechanisms for long video understanding predominantly rely on closed-loop self-reflection within internal parameters. Lacking objective external evidence, models are frequently trapped in blind confidence and often fail to correct errors. Furthermore, applying reinforcement learning to multi-stage reflection pipelines introduces severe policy coupling, which is exacerbated by a critical scarcity of dedicated training data. To address these limitations, this work proposes Reflect-R1, the first Evidence-Driven self-correction framework for long video understanding. The framework constructs a three-stage pipeline consisting of intuition, verification, and arbitration. By dynamically retrieving objective visual evidence to verify initial intuitions and autonomously executing multiple temporal searches to resolve conflicts, it completely breaks the hallucination loop. To overcome policy coupling, we design a stage-decoupled reinforcement learning algorithm named SD-GRPO that independently computes advantage functions across different reasoning stages. Concurrently, we construct a dataset of 120K samples to bridge the training data gap. Extensive experiments on benchmarks such as VideoMME and LongVideoBench demonstrate that Reflect-R1 achieves state-of-the-art performance. Our method significantly improves the genuine rectification rate and enables authentic self-correction strictly grounded in objective evidence.

  • 10 authors
·
Jun 25

Every View Counts: View-Consistent Panoptic Quality for Multi-view Panoptic Segmentation

Multi-view panoptic segmentation assigns a semantic class and a scene-level instance ID to every pixel of an unordered set of images, and recent feed-forward 3D models predict these labels for the input views in a single forward pass. Their predictions, however, have been evaluated with the scene-level PQ (PQ^scene) borrowed from per-scene optimization methods, typically on rendered held-out views. PQ^scene tiles all views of a scene into a single image, so that a missed appearance or a change of ID lowers the score of the matched pair only in proportion to its area. We propose View-Consistent Panoptic Quality (VC-PQ), which extends PQ from a single image to a set of input views, counts equally every view in which an instance is visible, and penalizes a prediction that is not visible in the same views as its ground truth. A decomposition of VC-PQ attributes the score a method loses to mask accuracy, view consistency, and the matching threshold. A single additional parameter recovers the area weighting of tiling for comparison. Under a fixed evaluation protocol on ScanNet++ and ScanNetv2, recent feed-forward methods are evaluated with VC-PQ and PQ^scene, and the decomposition shows where each of them loses its score. Controlled perturbations of the ground truth show that VC-PQ responds to the number of views in which an instance is missed or changes ID, whereas PQ^scene responds to their area. The aim of this work is to make view consistency part of the evaluation of multi-view panoptic segmentation, with VC-PQ reported alongside PQ^scene.

  • 4 authors
·
Oct 4

Toward effective protection against diffusion based mimicry through score distillation

While generative diffusion models excel in producing high-quality images, they can also be misused to mimic authorized images, posing a significant threat to AI systems. Efforts have been made to add calibrated perturbations to protect images from diffusion-based mimicry pipelines. However, most of the existing methods are too ineffective and even impractical to be used by individual users due to their high computation and memory requirements. In this work, we present novel findings on attacking latent diffusion models (LDM) and propose new plug-and-play strategies for more effective protection. In particular, we explore the bottleneck in attacking an LDM, discovering that the encoder module rather than the denoiser module is the vulnerable point. Based on this insight, we present our strategy using Score Distillation Sampling (SDS) to double the speed of protection and reduce memory occupation by half without compromising its strength. Additionally, we provide a robust protection strategy by counterintuitively minimizing the semantic loss, which can assist in generating more natural perturbations. Finally, we conduct extensive experiments to substantiate our findings and comprehensively evaluate our newly proposed strategies. We hope our insights and protective measures can contribute to better defense against malicious diffusion-based mimicry, advancing the development of secure AI systems. The code is available in https://github.com/xavihart/Diff-Protect

  • 4 authors
·
Oct 2, 2023

Highly Accurate Dichotomous Image Segmentation

We present a systematic study on a new task called dichotomous image segmentation (DIS) , which aims to segment highly accurate objects from natural images. To this end, we collected the first large-scale DIS dataset, called DIS5K, which contains 5,470 high-resolution (e.g., 2K, 4K or larger) images covering camouflaged, salient, or meticulous objects in various backgrounds. DIS is annotated with extremely fine-grained labels. Besides, we introduce a simple intermediate supervision baseline (IS-Net) using both feature-level and mask-level guidance for DIS model training. IS-Net outperforms various cutting-edge baselines on the proposed DIS5K, making it a general self-learned supervision network that can facilitate future research in DIS. Further, we design a new metric called human correction efforts (HCE) which approximates the number of mouse clicking operations required to correct the false positives and false negatives. HCE is utilized to measure the gap between models and real-world applications and thus can complement existing metrics. Finally, we conduct the largest-scale benchmark, evaluating 16 representative segmentation models, providing a more insightful discussion regarding object complexities, and showing several potential applications (e.g., background removal, art design, 3D reconstruction). Hoping these efforts can open up promising directions for both academic and industries. Project page: https://xuebinqin.github.io/dis/index.html.

  • 6 authors
·
Mar 6, 2022

SCOOTER: A Human Evaluation Framework for Unrestricted Adversarial Examples

Unrestricted adversarial attacks aim to fool computer vision models without being constrained by ell_p-norm bounds to remain imperceptible to humans, for example, by changing an object's color. This allows attackers to circumvent traditional, norm-bounded defense strategies such as adversarial training or certified defense strategies. However, due to their unrestricted nature, there are also no guarantees of norm-based imperceptibility, necessitating human evaluations to verify just how authentic these adversarial examples look. While some related work assesses this vital quality of adversarial attacks, none provide statistically significant insights. This issue necessitates a unified framework that supports and streamlines such an assessment for evaluating and comparing unrestricted attacks. To close this gap, we introduce SCOOTER - an open-source, statistically powered framework for evaluating unrestricted adversarial examples. Our contributions are: (i) best-practice guidelines for crowd-study power, compensation, and Likert equivalence bounds to measure imperceptibility; (ii) the first large-scale human vs. model comparison across 346 human participants showing that three color-space attacks and three diffusion-based attacks fail to produce imperceptible images. Furthermore, we found that GPT-4o can serve as a preliminary test for imperceptibility, but it only consistently detects adversarial examples for four out of six tested attacks; (iii) open-source software tools, including a browser-based task template to collect annotations and analysis scripts in Python and R; (iv) an ImageNet-derived benchmark dataset containing 3K real images, 7K adversarial examples, and over 34K human ratings. Our findings demonstrate that automated vision systems do not align with human perception, reinforcing the need for a ground-truth SCOOTER benchmark.

  • 7 authors
·
Jul 10, 2025

Scaling Artificial Intelligence for Multi-Tumor Early Detection with More Reports, Fewer Masks

Early tumor detection save lives. Each year, more than 300 million computed tomography (CT) scans are performed worldwide, offering a vast opportunity for effective cancer screening. However, detecting small or early-stage tumors on these CT scans remains challenging, even for experts. Artificial intelligence (AI) models can assist by highlighting suspicious regions, but training such models typically requires extensive tumor masks--detailed, voxel-wise outlines of tumors manually drawn by radiologists. Drawing these masks is costly, requiring years of effort and millions of dollars. In contrast, nearly every CT scan in clinical practice is already accompanied by medical reports describing the tumor's size, number, appearance, and sometimes, pathology results--information that is rich, abundant, and often underutilized for AI training. We introduce R-Super, which trains AI to segment tumors that match their descriptions in medical reports. This approach scales AI training with large collections of readily available medical reports, substantially reducing the need for manually drawn tumor masks. When trained on 101,654 reports, AI models achieved performance comparable to those trained on 723 masks. Combining reports and masks further improved sensitivity by +13% and specificity by +8%, surpassing radiologists in detecting five of the seven tumor types. Notably, R-Super enabled segmentation of tumors in the spleen, gallbladder, prostate, bladder, uterus, and esophagus, for which no public masks or AI models previously existed. This study challenges the long-held belief that large-scale, labor-intensive tumor mask creation is indispensable, establishing a scalable and accessible path toward early detection across diverse tumor types. We plan to release our trained models, code, and dataset at https://github.com/MrGiovanni/R-Super

  • 23 authors
·
Oct 16, 2025

Pluralistic Salient Object Detection

We introduce pluralistic salient object detection (PSOD), a novel task aimed at generating multiple plausible salient segmentation results for a given input image. Unlike conventional SOD methods that produce a single segmentation mask for salient objects, this new setting recognizes the inherent complexity of real-world images, comprising multiple objects, and the ambiguity in defining salient objects due to different user intentions. To study this task, we present two new SOD datasets "DUTS-MM" and "DUS-MQ", along with newly designed evaluation metrics. DUTS-MM builds upon the DUTS dataset but enriches the ground-truth mask annotations from three aspects which 1) improves the mask quality especially for boundary and fine-grained structures; 2) alleviates the annotation inconsistency issue; and 3) provides multiple ground-truth masks for images with saliency ambiguity. DUTS-MQ consists of approximately 100K image-mask pairs with human-annotated preference scores, enabling the learning of real human preferences in measuring mask quality. Building upon these two datasets, we propose a simple yet effective pluralistic SOD baseline based on a Mixture-of-Experts (MOE) design. Equipped with two prediction heads, it simultaneously predicts multiple masks using different query prompts and predicts human preference scores for each mask candidate. Extensive experiments and analyses underscore the significance of our proposed datasets and affirm the effectiveness of our PSOD framework.

  • 7 authors
·
Sep 3, 2024

One Flight Over the Gap: A Survey from Perspective to Panoramic Vision

Driven by the demand for spatial intelligence and holistic scene perception, omnidirectional images (ODIs), which provide a complete 360 field of view, are receiving growing attention across diverse applications such as virtual reality, autonomous driving, and embodied robotics. Despite their unique characteristics, ODIs exhibit remarkable differences from perspective images in geometric projection, spatial distribution, and boundary continuity, making it challenging for direct domain adaption from perspective methods. This survey reviews recent panoramic vision techniques with a particular emphasis on the perspective-to-panorama adaptation. We first revisit the panoramic imaging pipeline and projection methods to build the prior knowledge required for analyzing the structural disparities. Then, we summarize three challenges of domain adaptation: severe geometric distortions near the poles, non-uniform sampling in Equirectangular Projection (ERP), and periodic boundary continuity. Building on this, we cover 20+ representative tasks drawn from more than 300 research papers in two dimensions. On one hand, we present a cross-method analysis of representative strategies for addressing panoramic specific challenges across different tasks. On the other hand, we conduct a cross-task comparison and classify panoramic vision into four major categories: visual quality enhancement and assessment, visual understanding, multimodal understanding, and visual generation. In addition, we discuss open challenges and future directions in data, models, and applications that will drive the advancement of panoramic vision research. We hope that our work can provide new insight and forward looking perspectives to advance the development of panoramic vision technologies. Our project page is https://insta360-research-team.github.io/Survey-of-Panorama

  • 11 authors
·
Sep 4, 2025

Scale-aware Adaptive Supervised Network with Limited Medical Annotations

Medical image segmentation faces critical challenges in semi-supervised learning scenarios due to severe annotation scarcity requiring expert radiological knowledge, significant inter-annotator variability across different viewpoints and expertise levels, and inadequate multi-scale feature integration for precise boundary delineation in complex anatomical structures. Existing semi-supervised methods demonstrate substantial performance degradation compared to fully supervised approaches, particularly in small target segmentation and boundary refinement tasks. To address these fundamental challenges, we propose SASNet (Scale-aware Adaptive Supervised Network), a dual-branch architecture that leverages both low-level and high-level feature representations through novel scale-aware adaptive reweight mechanisms. Our approach introduces three key methodological innovations, including the Scale-aware Adaptive Reweight strategy that dynamically weights pixel-wise predictions using temporal confidence accumulation, the View Variance Enhancement mechanism employing 3D Fourier domain transformations to simulate annotation variability, and segmentation-regression consistency learning through signed distance map algorithms for enhanced boundary precision. These innovations collectively address the core limitations of existing semi-supervised approaches by integrating spatial, temporal, and geometric consistency principles within a unified optimization framework. Comprehensive evaluation across LA, Pancreas-CT, and BraTS datasets demonstrates that SASNet achieves superior performance with limited labeled data, surpassing state-of-the-art semi-supervised methods while approaching fully supervised performance levels. The source code for SASNet is available at https://github.com/HUANGLIZI/SASNet.

  • 5 authors
·
Jan 2

PreviewDiff: Multimodal Critic-Guided Search over Diffusion Latents

Diffusion models can produce striking images and videos, but they still struggle with the compositional details that make a generation faithful to a prompt, such as object counts, attribute binding, spatial relations, and temporally grounded actions. A common way to improve prompt satisfaction is to spend more compute at test time through Best-of-N sampling, but final-sample selection is fixed. Best-of-N can only choose among completed outputs and cannot repair a promising trajectory before it fails. We introduce PreviewDiff, a training-free test-time search method that turns diffusion sampling from scalar search into a multimodal critic-guided search over intermediate latents. At selected denoising checkpoints, PreviewDiff decodes a partial preview, asks a multimodal judge to score and critique it, and uses the resulting natural-language feedback to branch over semantic prompt edits and locally re-noised latent continuations. These branches are then scored and selectively rolled forward, allowing verifier compute to guide generation while the sample is still editable. Across image and video generation benchmarks, PreviewDiff consistently improves over budget-matched Best-of-N selection and strong scalar-search baselines. Ablations show that earlier interventions and increased search width provide the largest gains, while deeper search and additional semantic variants offer complementary improvements. PreviewDiff demonstrates that multimodal feedback is most useful not only as a final verifier, but as an active controller inside the denoising process.

google Google
·
Sep 28 1

What Paired Evaluations Reveal under Visual Perturbations

Robustness evaluation must examine diverse visual perturbations, while benchmarks cover only some real-world conditions and physical testing is costly. Paired evaluations link clean and perturbed predictions for the same image, capturing changes in correctness, confidence, and acceptance beyond aggregate accuracy. We investigate how this image correspondence supports two needs in robustness evaluation: interpreting paired evaluation results and prioritizing samples for physical testing. To interpret paired evaluation results, we fix both sets of prediction records and vary their correspondence within each class. We prove that classwise correct-correct counts give the same sharp bounds on lost acceptance and mean true-class probability decrease among retained-correct inputs as any feasible five-state refinement. Distinguishing persistent from changed wrong answers can further constrain accepted-error transitions, while shared correspondence can establish policy orderings left unresolved by separate cost intervals. To prioritize samples for physical testing, we retain each image's synthetic responses and rank clean-correct images by their mean true-class probability under corruption. Across 44 classifiers, testing the highest-risk 20% finds 67% and 45% of failures under mild screen and print recaptures, versus 58% and 36% for clean confidence and 60% and 37% for an equal-size natural-transformation average. With both probability averaging and an A3Rank scoring adaptation, the tested corruption set yields higher mean failure recall than the natural-transform set; differences between scores depend on the source and budget. Together, these findings show that the value of correspondence depends on the evaluation objective: classwise counts suffice for specified reliability bounds, while image-specific synthetic responses improve the allocation of physical tests within the evaluated pool.

  • 7 authors
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Sep 27

Eevee: Towards Close-up High-resolution Video-based Virtual Try-on

Video virtual try-on technology provides a cost-effective solution for creating marketing videos in fashion e-commerce. However, its practical adoption is hindered by two critical limitations. First, the reliance on a single garment image as input in current virtual try-on datasets limits the accurate capture of realistic texture details. Second, most existing methods focus solely on generating full-shot virtual try-on videos, neglecting the business's demand for videos that also provide detailed close-ups. To address these challenges, we introduce a high-resolution dataset for video-based virtual try-on. This dataset offers two key features. First, it provides more detailed information on the garments, which includes high-fidelity images with detailed close-ups and textual descriptions; Second, it uniquely includes full-shot and close-up try-on videos of real human models. Furthermore, accurately assessing consistency becomes significantly more critical for the close-up videos, which demand high-fidelity preservation of garment details. To facilitate such fine-grained evaluation, we propose a new garment consistency metric VGID (Video Garment Inception Distance) that quantifies the preservation of both texture and structure. Our experiments validate these contributions. We demonstrate that by utilizing the detailed images from our dataset, existing video generation models can extract and incorporate texture features, significantly enhancing the realism and detail fidelity of virtual try-on results. Furthermore, we conduct a comprehensive benchmark of recent models. The benchmark effectively identifies the texture and structural preservation problems among current methods.

  • 10 authors
·
Nov 24, 2025

CellCLIP -- Learning Perturbation Effects in Cell Painting via Text-Guided Contrastive Learning

High-content screening (HCS) assays based on high-throughput microscopy techniques such as Cell Painting have enabled the interrogation of cells' morphological responses to perturbations at an unprecedented scale. The collection of such data promises to facilitate a better understanding of the relationships between different perturbations and their effects on cellular state. Towards achieving this goal, recent advances in cross-modal contrastive learning could, in theory, be leveraged to learn a unified latent space that aligns perturbations with their corresponding morphological effects. However, the application of such methods to HCS data is not straightforward due to substantial differences in the semantics of Cell Painting images compared to natural images, and the difficulty of representing different classes of perturbations (e.g., small molecule vs CRISPR gene knockout) in a single latent space. In response to these challenges, here we introduce CellCLIP, a cross-modal contrastive learning framework for HCS data. CellCLIP leverages pre-trained image encoders coupled with a novel channel encoding scheme to better capture relationships between different microscopy channels in image embeddings, along with natural language encoders for representing perturbations. Our framework outperforms current open-source models, demonstrating the best performance in both cross-modal retrieval and biologically meaningful downstream tasks while also achieving significant reductions in computation time.

  • 4 authors
·
May 16, 2025