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Mar 17

Towards Explainable Anticancer Compound Sensitivity Prediction via Multimodal Attention-based Convolutional Encoders

In line with recent advances in neural drug design and sensitivity prediction, we propose a novel architecture for interpretable prediction of anticancer compound sensitivity using a multimodal attention-based convolutional encoder. Our model is based on the three key pillars of drug sensitivity: compounds' structure in the form of a SMILES sequence, gene expression profiles of tumors and prior knowledge on intracellular interactions from protein-protein interaction networks. We demonstrate that our multiscale convolutional attention-based (MCA) encoder significantly outperforms a baseline model trained on Morgan fingerprints, a selection of encoders based on SMILES as well as previously reported state of the art for multimodal drug sensitivity prediction (R2 = 0.86 and RMSE = 0.89). Moreover, the explainability of our approach is demonstrated by a thorough analysis of the attention weights. We show that the attended genes significantly enrich apoptotic processes and that the drug attention is strongly correlated with a standard chemical structure similarity index. Finally, we report a case study of two receptor tyrosine kinase (RTK) inhibitors acting on a leukemia cell line, showcasing the ability of the model to focus on informative genes and submolecular regions of the two compounds. The demonstrated generalizability and the interpretability of our model testify its potential for in-silico prediction of anticancer compound efficacy on unseen cancer cells, positioning it as a valid solution for the development of personalized therapies as well as for the evaluation of candidate compounds in de novo drug design.

  • 6 authors
·
Apr 25, 2019

GUI-AIMA: Aligning Intrinsic Multimodal Attention with a Context Anchor for GUI Grounding

Graphical user interface (GUI) grounding is a key function of computer-use agents, which maps natural-language instructions to actionable screen regions. Existing approaches based on Multimodal Large Language Models (MLLMs) typically formulate it as a text-based coordinate generation task, yet directly generating precise coordinates from visual inputs remains challenging and computationally intensive. An intuitive way to implement GUI grounding is to first select visual patches relevant to the instructions and then determine the precise click location within those patches. Based on the observations that general MLLMs have some native grounding capability, nested within their attentions, we propose GUI-AIMA, an attention-based and coordinate-free supervised fine-tuning framework for efficient GUI grounding. GUI-AIMA aligns the intrinsic multimodal attention of MLLMs with patch-wise grounding signals. These signals are calculated adaptively for diverse user instructions by multi-head aggregation on simplified query-visual attention matrices. Besides, its coordinate-free manner can easily integrate a plug-and-play zoom-in stage. GUI-AIMA-3B was trained with only 85k screenshots, demonstrating exceptional data efficiency and verifying that light training can trigger the native grounding capability of MLLMs. It achieves state-of-the-art performance among 3B models, attaining an average accuracy of 58.6% on ScreenSpot-Pro and 62.2% on OSWorld-G. Project page: https://github.com/sjz5202/GUI-AIMA

  • 7 authors
·
Nov 2, 2025 1

CreativeSynth: Creative Blending and Synthesis of Visual Arts based on Multimodal Diffusion

Large-scale text-to-image generative models have made impressive strides, showcasing their ability to synthesize a vast array of high-quality images. However, adapting these models for artistic image editing presents two significant challenges. Firstly, users struggle to craft textual prompts that meticulously detail visual elements of the input image. Secondly, prevalent models, when effecting modifications in specific zones, frequently disrupt the overall artistic style, complicating the attainment of cohesive and aesthetically unified artworks. To surmount these obstacles, we build the innovative unified framework CreativeSynth, which is based on a diffusion model with the ability to coordinate multimodal inputs and multitask in the field of artistic image generation. By integrating multimodal features with customized attention mechanisms, CreativeSynth facilitates the importation of real-world semantic content into the domain of art through inversion and real-time style transfer. This allows for the precise manipulation of image style and content while maintaining the integrity of the original model parameters. Rigorous qualitative and quantitative evaluations underscore that CreativeSynth excels in enhancing artistic images' fidelity and preserves their innate aesthetic essence. By bridging the gap between generative models and artistic finesse, CreativeSynth becomes a custom digital palette.

  • 8 authors
·
Jan 25, 2024 1

MoRE: Multi-Modal Contrastive Pre-training with Transformers on X-Rays, ECGs, and Diagnostic Report

In this paper, we introduce a novel Multi-Modal Contrastive Pre-training Framework that synergistically combines X-rays, electrocardiograms (ECGs), and radiology/cardiology reports. Our approach leverages transformers to encode these diverse modalities into a unified representation space, aiming to enhance diagnostic accuracy and facilitate comprehensive patient assessments. We utilize LoRA-Peft to significantly reduce trainable parameters in the LLM and incorporate recent linear attention dropping strategy in the Vision Transformer(ViT) for smoother attention. Furthermore, we provide novel multimodal attention explanations and retrieval for our model. To the best of our knowledge, we are the first to propose an integrated model that combines X-ray, ECG, and Radiology/Cardiology Report with this approach. By utilizing contrastive loss, MoRE effectively aligns modality-specific features into a coherent embedding, which supports various downstream tasks such as zero-shot classification and multimodal retrieval. Employing our proposed methodology, we achieve state-of-the-art (SOTA) on the Mimic-IV, CheXpert, Edema Severity, and PtbXl downstream datasets, surpassing existing multimodal approaches. Our proposed framework shows significant improvements in capturing intricate inter-modal relationships and its robustness in medical diagnosis that establishes a framework for future research in multimodal learning in the healthcare sector.

  • 4 authors
·
Oct 21, 2024

DeContext as Defense: Safe Image Editing in Diffusion Transformers

In-context diffusion models allow users to modify images with remarkable ease and realism. However, the same power raises serious privacy concerns: personal images can be easily manipulated for identity impersonation, misinformation, or other malicious uses, all without the owner's consent. While prior work has explored input perturbations to protect against misuse in personalized text-to-image generation, the robustness of modern, large-scale in-context DiT-based models remains largely unexamined. In this paper, we propose DeContext, a new method to safeguard input images from unauthorized in-context editing. Our key insight is that contextual information from the source image propagates to the output primarily through multimodal attention layers. By injecting small, targeted perturbations that weaken these cross-attention pathways, DeContext breaks this flow, effectively decouples the link between input and output. This simple defense is both efficient and robust. We further show that early denoising steps and specific transformer blocks dominate context propagation, which allows us to concentrate perturbations where they matter most. Experiments on Flux Kontext and Step1X-Edit show that DeContext consistently blocks unwanted image edits while preserving visual quality. These results highlight the effectiveness of attention-based perturbations as a powerful defense against image manipulation.

Trying Bilinear Pooling in Video-QA

Bilinear pooling (BLP) refers to a family of operations recently developed for fusing features from different modalities predominantly developed for VQA models. A bilinear (outer-product) expansion is thought to encourage models to learn interactions between two feature spaces and has experimentally outperformed `simpler' vector operations (concatenation and element-wise-addition/multiplication) on VQA benchmarks. Successive BLP techniques have yielded higher performance with lower computational expense and are often implemented alongside attention mechanisms. However, despite significant progress in VQA, BLP methods have not been widely applied to more recently explored video question answering (video-QA) tasks. In this paper, we begin to bridge this research gap by applying BLP techniques to various video-QA benchmarks, namely: TVQA, TGIF-QA, Ego-VQA and MSVD-QA. We share our results on the TVQA baseline model, and the recently proposed heterogeneous-memory-enchanced multimodal attention (HME) model. Our experiments include both simply replacing feature concatenation in the existing models with BLP, and a modified version of the TVQA baseline to accommodate BLP we name the `dual-stream' model. We find that our relatively simple integration of BLP does not increase, and mostly harms, performance on these video-QA benchmarks. Using recently proposed theoretical multimodal fusion taxonomies, we offer insight into why BLP-driven performance gain for video-QA benchmarks may be more difficult to achieve than in earlier VQA models. We suggest a few additional `best-practices' to consider when applying BLP to video-QA. We stress that video-QA models should carefully consider where the complex representational potential from BLP is actually needed to avoid computational expense on `redundant' fusion.

  • 4 authors
·
Dec 18, 2020

Inverse Virtual Try-On: Generating Multi-Category Product-Style Images from Clothed Individuals

While virtual try-on (VTON) systems aim to render a garment onto a target person image, this paper tackles the novel task of virtual try-off (VTOFF), which addresses the inverse problem: generating standardized product images of garments from real-world photos of clothed individuals. Unlike VTON, which must resolve diverse pose and style variations, VTOFF benefits from a consistent and well-defined output format -- typically a flat, lay-down-style representation of the garment -- making it a promising tool for data generation and dataset enhancement. However, existing VTOFF approaches face two major limitations: (i) difficulty in disentangling garment features from occlusions and complex poses, often leading to visual artifacts, and (ii) restricted applicability to single-category garments (e.g., upper-body clothes only), limiting generalization. To address these challenges, we present Text-Enhanced MUlti-category Virtual Try-Off (TEMU-VTOFF), a novel architecture featuring a dual DiT-based backbone with a modified multimodal attention mechanism for robust garment feature extraction. Our architecture is designed to receive garment information from multiple modalities like images, text, and masks to work in a multi-category setting. Finally, we propose an additional alignment module to further refine the generated visual details. Experiments on VITON-HD and Dress Code datasets show that TEMU-VTOFF sets a new state-of-the-art on the VTOFF task, significantly improving both visual quality and fidelity to the target garments.

  • 6 authors
·
May 27, 2025 1

CreatiDesign: A Unified Multi-Conditional Diffusion Transformer for Creative Graphic Design

Graphic design plays a vital role in visual communication across advertising, marketing, and multimedia entertainment. Prior work has explored automated graphic design generation using diffusion models, aiming to streamline creative workflows and democratize design capabilities. However, complex graphic design scenarios require accurately adhering to design intent specified by multiple heterogeneous user-provided elements (\eg images, layouts, and texts), which pose multi-condition control challenges for existing methods. Specifically, previous single-condition control models demonstrate effectiveness only within their specialized domains but fail to generalize to other conditions, while existing multi-condition methods often lack fine-grained control over each sub-condition and compromise overall compositional harmony. To address these limitations, we introduce CreatiDesign, a systematic solution for automated graphic design covering both model architecture and dataset construction. First, we design a unified multi-condition driven architecture that enables flexible and precise integration of heterogeneous design elements with minimal architectural modifications to the base diffusion model. Furthermore, to ensure that each condition precisely controls its designated image region and to avoid interference between conditions, we propose a multimodal attention mask mechanism. Additionally, we develop a fully automated pipeline for constructing graphic design datasets, and introduce a new dataset with 400K samples featuring multi-condition annotations, along with a comprehensive benchmark. Experimental results show that CreatiDesign outperforms existing models by a clear margin in faithfully adhering to user intent.

  • 9 authors
·
May 25, 2025

OmniDPO: A Preference Optimization Framework to Address Omni-Modal Hallucination

Recently, Omni-modal large language models (OLLMs) have sparked a new wave of research, achieving impressive results in tasks such as audio-video understanding and real-time environment perception. However, hallucination issues still persist. Similar to the bimodal setting, the priors from the text modality tend to dominate, leading OLLMs to rely more heavily on textual cues while neglecting visual and audio information. In addition, fully multimodal scenarios introduce new challenges. Most existing models align visual or auditory modalities with text independently during training, while ignoring the intrinsic correlations between video and its corresponding audio. This oversight results in hallucinations when reasoning requires interpreting hidden audio cues embedded in video content. To address these challenges, we propose OmniDPO, a preference-alignment framework designed to mitigate hallucinations in OLLMs. Specifically, OmniDPO incorporates two strategies: (1) constructing text-preference sample pairs to enhance the model's understanding of audio-video interactions; and (2) constructing multimodal-preference sample pairs to strengthen the model's attention to visual and auditory information. By tackling both challenges, OmniDPO effectively improves multimodal grounding and reduces hallucination. Experiments conducted on two OLLMs demonstrate that OmniDPO not only effectively mitigates multimodal hallucinations but also significantly enhances the models' reasoning capabilities across modalities. All code and datasets will be released upon paper acceptance.

  • 9 authors
·
Aug 31, 2025

PF-LHM: 3D Animatable Avatar Reconstruction from Pose-free Articulated Human Images

Reconstructing an animatable 3D human from casually captured images of an articulated subject without camera or human pose information is a practical yet challenging task due to view misalignment, occlusions, and the absence of structural priors. While optimization-based methods can produce high-fidelity results from monocular or multi-view videos, they require accurate pose estimation and slow iterative optimization, limiting scalability in unconstrained scenarios. Recent feed-forward approaches enable efficient single-image reconstruction but struggle to effectively leverage multiple input images to reduce ambiguity and improve reconstruction accuracy. To address these challenges, we propose PF-LHM, a large human reconstruction model that generates high-quality 3D avatars in seconds from one or multiple casually captured pose-free images. Our approach introduces an efficient Encoder-Decoder Point-Image Transformer architecture, which fuses hierarchical geometric point features and multi-view image features through multimodal attention. The fused features are decoded to recover detailed geometry and appearance, represented using 3D Gaussian splats. Extensive experiments on both real and synthetic datasets demonstrate that our method unifies single- and multi-image 3D human reconstruction, achieving high-fidelity and animatable 3D human avatars without requiring camera and human pose annotations. Code and models will be released to the public.

  • 10 authors
·
Jun 16, 2025

MASR: Self-Reflective Reasoning through Multimodal Hierarchical Attention Focusing for Agent-based Video Understanding

Even in the era of rapid advances in large models, video understanding remains a highly challenging task. Compared to texts or images, videos commonly contain more information with redundancy, requiring large models to properly allocate attention at a global level for comprehensive and accurate understanding. To address this, we propose a Multimodal hierarchical Attention focusing Self-reflective Reasoning (MASR) framework for agent-based video understanding. The key innovation lies in its ability to detect and prioritize segments of videos that are highly relevant to the query. Firstly, MASR realizes Multimodal Coarse-to-fine Relevance Sensing (MCRS) which enhances the correlation between the acquired contextual information and the query. Secondly, MASR employs Dilated Temporal Expansion (DTE) to mitigate the risk of missing crucial details when extracting semantic information from the focused frames selected through MCRS. By iteratively applying MCRS and DTE in the self-reflective reasoning process, MASR is able to adaptively adjust the attention to extract highly query-relevant context and therefore improve the response accuracy. In the EgoSchema dataset, MASR achieves a remarkable 5% performance gain over previous leading approaches. In the Next-QA and IntentQA datasets, it outperforms the state-of-the-art standards by 0.2% and 0.3% respectively. In the Video-MME dataset that contains long-term videos, MASR also performs better than other agent-based methods.

  • 7 authors
·
Apr 23, 2025

Looking Beyond Text: Reducing Language bias in Large Vision-Language Models via Multimodal Dual-Attention and Soft-Image Guidance

Large vision-language models (LVLMs) have achieved impressive results in various vision-language tasks. However, despite showing promising performance, LVLMs suffer from hallucinations caused by language bias, leading to diminished focus on images and ineffective visual comprehension. We identify two primary reasons for this bias: 1. Different scales of training data between the pretraining stage of LLM and multimodal alignment stage. 2. The learned inference bias due to short-term dependency of text data. Therefore, we propose LACING, a systemic framework designed to address the language bias of LVLMs with muLtimodal duAl-attention meChanIsm (MDA) aNd soft-image Guidance (IFG). Specifically, MDA introduces a parallel dual-attention mechanism that enhances the integration of visual inputs across the model. IFG introduces a learnable soft visual prompt during training and inference to replace visual inputs, designed to compel LVLMs to prioritize text inputs. Then, IFG further proposes a novel decoding strategy using the soft visual prompt to mitigate the model's over-reliance on adjacent text inputs. Comprehensive experiments demonstrate that our method effectively debiases LVLMs from their language bias, enhancing visual comprehension and reducing hallucinations without requiring additional training resources or data. The code and model are available at [lacing-lvlm.github.io](https://lacing-lvlm.github.io).

  • 7 authors
·
Nov 21, 2024

Multimodal Chain of Continuous Thought for Latent-Space Reasoning in Vision-Language Models

Many reasoning techniques for large multimodal models adapt language model approaches, such as Chain-of-Thought (CoT) prompting, which express reasoning as word sequences. While effective for text, these methods are suboptimal for multimodal contexts, struggling to align audio, visual, and textual information dynamically. To explore an alternative paradigm, we propose the Multimodal Chain of Continuous Thought (MCOUT), which enables reasoning directly in a joint latent space rather than in natural language. In MCOUT, the reasoning state is represented as a continuous hidden vector, iteratively refined and aligned with visual and textual embeddings, inspired by human reflective cognition. We develop two variants: MCOUT-Base, which reuses the language model`s last hidden state as the continuous thought for iterative reasoning, and MCOUT-Multi, which integrates multimodal latent attention to strengthen cross-modal alignment between visual and textual features. Experiments on benchmarks including MMMU, ScienceQA, and MMStar show that MCOUT consistently improves multimodal reasoning, yielding up to 8.23% accuracy gains over strong baselines and improving BLEU scores up to 8.27% across multiple-choice and open-ended tasks. These findings highlight latent continuous reasoning as a promising direction for advancing LMMs beyond language-bound CoT, offering a scalable framework for human-like reflective multimodal inference. Code is available at https://github.com/Hanhpt23/OmniMod.

  • 2 authors
·
Aug 17, 2025

Investigating Acoustic-Textual Emotional Inconsistency Information for Automatic Depression Detection

Previous studies have demonstrated that emotional features from a single acoustic sentiment label can enhance depression diagnosis accuracy. Additionally, according to the Emotion Context-Insensitivity theory and our pilot study, individuals with depression might convey negative emotional content in an unexpectedly calm manner, showing a high degree of inconsistency in emotional expressions during natural conversations. So far, few studies have recognized and leveraged the emotional expression inconsistency for depression detection. In this paper, a multimodal cross-attention method is presented to capture the Acoustic-Textual Emotional Inconsistency (ATEI) information. This is achieved by analyzing the intricate local and long-term dependencies of emotional expressions across acoustic and textual domains, as well as the mismatch between the emotional content within both domains. A Transformer-based model is then proposed to integrate this ATEI information with various fusion strategies for detecting depression. Furthermore, a scaling technique is employed to adjust the ATEI feature degree during the fusion process, thereby enhancing the model's ability to discern patients with depression across varying levels of severity. To best of our knowledge, this work is the first to incorporate emotional expression inconsistency information into depression detection. Experimental results on a counseling conversational dataset illustrate the effectiveness of our method.

  • 7 authors
·
Dec 8, 2024

Layer-wise Instance Binding for Regional and Occlusion Control in Text-to-Image Diffusion Transformers

Region-instructed layout control in text-to-image generation is highly practical, yet existing methods suffer from limitations: (i) training-based approaches inherit data bias and often degrade image quality, and (ii) current techniques struggle with occlusion order, limiting real-world usability. To address these issues, we propose LayerBind. By modeling regional generation as distinct layers and binding them during the generation, our method enables precise regional and occlusion controllability. Our motivation stems from the observation that spatial layout and occlusion are established at a very early denoising stage, suggesting that rearranging the early latent structure is sufficient to modify the final output. Building on this, we structure the scheme into two phases: instance initialization and subsequent semantic nursing. (1) First, leveraging the contextual sharing mechanism in multimodal joint attention, Layer-wise Instance Initialization creates per-instance branches that attend to their own regions while anchoring to the shared background. At a designated early step, these branches are fused according to the layer order to form a unified latent with a pre-established layout. (2) Then, Layer-wise Semantic Nursing reinforces regional details and maintains the occlusion order via a layer-wise attention enhancement. Specifically, a sequential layered attention path operates alongside the standard global path, with updates composited under a layer-transparency scheduler. LayerBind is training-free and plug-and-play, serving as a regional and occlusion controller across Diffusion Transformers. Beyond generation, it natively supports editable workflows, allowing for flexible modifications like changing instances or rearranging visible orders. Both qualitative and quantitative results demonstrate LayerBind's effectiveness, highlighting its strong potential for creative applications.

  • 9 authors
·
Mar 5

MODA: MOdular Duplex Attention for Multimodal Perception, Cognition, and Emotion Understanding

Multimodal large language models (MLLMs) recently showed strong capacity in integrating data among multiple modalities, empowered by a generalizable attention architecture. Advanced methods predominantly focus on language-centric tuning while less exploring multimodal tokens mixed through attention, posing challenges in high-level tasks that require fine-grained cognition and emotion understanding. In this work, we identify the attention deficit disorder problem in multimodal learning, caused by inconsistent cross-modal attention and layer-by-layer decayed attention activation. To address this, we propose a novel attention mechanism, termed MOdular Duplex Attention (MODA), simultaneously conducting the inner-modal refinement and inter-modal interaction. MODA employs a correct-after-align strategy to effectively decouple modality alignment from cross-layer token mixing. In the alignment phase, tokens are mapped to duplex modality spaces based on the basis vectors, enabling the interaction between visual and language modality. Further, the correctness of attention scores is ensured through adaptive masked attention, which enhances the model's flexibility by allowing customizable masking patterns for different modalities. Extensive experiments on 21 benchmark datasets verify the effectiveness of MODA in perception, cognition, and emotion tasks. Source code and demo are available in https://zzcheng.top/MODA.

  • 10 authors
·
Jul 6, 2025

OmniScene: Attention-Augmented Multimodal 4D Scene Understanding for Autonomous Driving

Human vision is capable of transforming two-dimensional observations into an egocentric three-dimensional scene understanding, which underpins the ability to translate complex scenes and exhibit adaptive behaviors. This capability, however, remains lacking in current autonomous driving systems, where mainstream approaches primarily rely on depth-based 3D reconstruction rather than true scene understanding. To address this limitation, we propose a novel human-like framework called OmniScene. First, we introduce the OmniScene Vision-Language Model (OmniVLM), a vision-language framework that integrates multi-view and temporal perception for holistic 4D scene understanding. Then, harnessing a teacher-student OmniVLM architecture and knowledge distillation, we embed textual representations into 3D instance features for semantic supervision, enriching feature learning, and explicitly capturing human-like attentional semantics. These feature representations are further aligned with human driving behaviors, forming a more human-like perception-understanding-action architecture. In addition, we propose a Hierarchical Fusion Strategy (HFS) to address imbalances in modality contributions during multimodal integration. Our approach adaptively calibrates the relative significance of geometric and semantic features at multiple abstraction levels, enabling the synergistic use of complementary cues from visual and textual modalities. This learnable dynamic fusion enables a more nuanced and effective exploitation of heterogeneous information. We evaluate OmniScene comprehensively on the nuScenes dataset, benchmarking it against over ten state-of-the-art models across various tasks. Our approach consistently achieves superior results, establishing new benchmarks in perception, prediction, planning, and visual question answering.

  • 8 authors
·
Sep 24, 2025

Modality Alignment with Multi-scale Bilateral Attention for Multimodal Recommendation

Multimodal recommendation systems are increasingly becoming foundational technologies for e-commerce and content platforms, enabling personalized services by jointly modeling users' historical behaviors and the multimodal features of items (e.g., visual and textual). However, most existing methods rely on either static fusion strategies or graph-based local interaction modeling, facing two critical limitations: (1) insufficient ability to model fine-grained cross-modal associations, leading to suboptimal fusion quality; and (2) a lack of global distribution-level consistency, causing representational bias. To address these, we propose MambaRec, a novel framework that integrates local feature alignment and global distribution regularization via attention-guided learning. At its core, we introduce the Dilated Refinement Attention Module (DREAM), which uses multi-scale dilated convolutions with channel-wise and spatial attention to align fine-grained semantic patterns between visual and textual modalities. This module captures hierarchical relationships and context-aware associations, improving cross-modal semantic modeling. Additionally, we apply Maximum Mean Discrepancy (MMD) and contrastive loss functions to constrain global modality alignment, enhancing semantic consistency. This dual regularization reduces mode-specific deviations and boosts robustness. To improve scalability, MambaRec employs a dimensionality reduction strategy to lower the computational cost of high-dimensional multimodal features. Extensive experiments on real-world e-commerce datasets show that MambaRec outperforms existing methods in fusion quality, generalization, and efficiency. Our code has been made publicly available at https://github.com/rkl71/MambaRec.

  • 3 authors
·
Sep 10, 2025 2

Seeing is Understanding: Unlocking Causal Attention into Modality-Mutual Attention for Multimodal LLMs

Recent Multimodal Large Language Models (MLLMs) have demonstrated significant progress in perceiving and reasoning over multimodal inquiries, ushering in a new research era for foundation models. However, vision-language misalignment in MLLMs has emerged as a critical challenge, where the textual responses generated by these models are not factually aligned with the given text-image inputs. Existing efforts to address vision-language misalignment have focused on developing specialized vision-language connectors or leveraging visual instruction tuning from diverse domains. In this paper, we tackle this issue from a fundamental yet unexplored perspective by revisiting the core architecture of MLLMs. Most MLLMs are typically built on decoder-only LLMs consisting of a causal attention mechanism, which limits the ability of earlier modalities (e.g., images) to incorporate information from later modalities (e.g., text). To address this problem, we propose AKI, a novel MLLM that unlocks causal attention into modality-mutual attention (MMA) to enable image tokens to attend to text tokens. This simple yet effective design allows AKI to achieve superior performance in 12 multimodal understanding benchmarks (+7.2% on average) without introducing additional parameters and increasing training time. Our MMA design is intended to be generic, allowing for application across various modalities, and scalable to accommodate diverse multimodal scenarios. The code is publicly available at https://github.com/sony/aki, and we will release our AKI-4B model to encourage further advancements in MLLMs across various directions.

  • 4 authors
·
Mar 4, 2025

EPAM-Net: An Efficient Pose-driven Attention-guided Multimodal Network for Video Action Recognition

Existing multimodal-based human action recognition approaches are computationally intensive, limiting their deployment in real-time applications. In this work, we present a novel and efficient pose-driven attention-guided multimodal network (EPAM-Net) for action recognition in videos. Specifically, we propose eXpand temporal Shift (X-ShiftNet) convolutional architectures for RGB and pose streams to capture spatio-temporal features from RGB videos and their skeleton sequences. The X-ShiftNet tackles the high computational cost of the 3D CNNs by integrating the Temporal Shift Module (TSM) into an efficient 2D CNN, enabling efficient spatiotemporal learning. Then skeleton features are utilized to guide the visual network stream, focusing on keyframes and their salient spatial regions using the proposed spatial-temporal attention block. Finally, the predictions of the two streams are fused for final classification. The experimental results show that our method, with a significant reduction in floating-point operations (FLOPs), outperforms and competes with the state-of-the-art methods on NTU RGB-D 60, NTU RGB-D 120, PKU-MMD, and Toyota SmartHome datasets. The proposed EPAM-Net provides up to a 72.8x reduction in FLOPs and up to a 48.6x reduction in the number of network parameters. The code will be available at https://github.com/ahmed-nady/Multimodal-Action-Recognition.

  • 3 authors
·
Aug 9, 2024

Routing with Self-Attention for Multimodal Capsule Networks

The task of multimodal learning has seen a growing interest recently as it allows for training neural architectures based on different modalities such as vision, text, and audio. One challenge in training such models is that they need to jointly learn semantic concepts and their relationships across different input representations. Capsule networks have been shown to perform well in context of capturing the relation between low-level input features and higher-level concepts. However, capsules have so far mainly been used only in small-scale fully supervised settings due to the resource demand of conventional routing algorithms. We present a new multimodal capsule network that allows us to leverage the strength of capsules in the context of a multimodal learning framework on large amounts of video data. To adapt the capsules to large-scale input data, we propose a novel routing by self-attention mechanism that selects relevant capsules which are then used to generate a final joint multimodal feature representation. This allows not only for robust training with noisy video data, but also to scale up the size of the capsule network compared to traditional routing methods while still being computationally efficient. We evaluate the proposed architecture by pretraining it on a large-scale multimodal video dataset and applying it on four datasets in two challenging downstream tasks. Results show that the proposed multimodal capsule network is not only able to improve results compared to other routing techniques, but also achieves competitive performance on the task of multimodal learning.

  • 10 authors
·
Dec 1, 2021

Wings: Learning Multimodal LLMs without Text-only Forgetting

Multimodal large language models (MLLMs), initiated with a trained LLM, first align images with text and then fine-tune on multimodal mixed inputs. However, the MLLM catastrophically forgets the text-only instructions, which do not include images and can be addressed within the initial LLM. In this paper, we present Wings, a novel MLLM that excels in both text-only dialogues and multimodal comprehension. Analyzing MLLM attention in multimodal instructions reveals that text-only forgetting is related to the attention shifts from pre-image to post-image text. From that, we construct extra modules that act as the boosted learner to compensate for the attention shift. The complementary visual and textual learners, like "wings" on either side, are connected in parallel within each layer's attention block. Initially, image and text inputs are aligned with visual learners operating alongside the main attention, balancing focus on visual elements. Textual learners are later collaboratively integrated with attention-based routing to blend the outputs of the visual and textual learners. We design the Low-Rank Residual Attention (LoRRA) to guarantee high efficiency for learners. Our experimental results demonstrate that Wings outperforms equally-scaled MLLMs in both text-only and visual question-answering tasks. On a newly constructed Interleaved Image-Text (IIT) benchmark, Wings exhibits superior performance from text-only-rich to multimodal-rich question-answering tasks.

  • 10 authors
·
Jun 5, 2024

Improving Medical Predictions by Irregular Multimodal Electronic Health Records Modeling

Health conditions among patients in intensive care units (ICUs) are monitored via electronic health records (EHRs), composed of numerical time series and lengthy clinical note sequences, both taken at irregular time intervals. Dealing with such irregularity in every modality, and integrating irregularity into multimodal representations to improve medical predictions, is a challenging problem. Our method first addresses irregularity in each single modality by (1) modeling irregular time series by dynamically incorporating hand-crafted imputation embeddings into learned interpolation embeddings via a gating mechanism, and (2) casting a series of clinical note representations as multivariate irregular time series and tackling irregularity via a time attention mechanism. We further integrate irregularity in multimodal fusion with an interleaved attention mechanism across temporal steps. To the best of our knowledge, this is the first work to thoroughly model irregularity in multimodalities for improving medical predictions. Our proposed methods for two medical prediction tasks consistently outperforms state-of-the-art (SOTA) baselines in each single modality and multimodal fusion scenarios. Specifically, we observe relative improvements of 6.5\%, 3.6\%, and 4.3\% in F1 for time series, clinical notes, and multimodal fusion, respectively. These results demonstrate the effectiveness of our methods and the importance of considering irregularity in multimodal EHRs.

  • 5 authors
·
Oct 18, 2022

Accountable Textual-Visual Chat Learns to Reject Human Instructions in Image Re-creation

The recent success of ChatGPT and GPT-4 has drawn widespread attention to multimodal dialogue systems. However, the academia community lacks a dataset that can validate the multimodal generation capabilities of Visual Language Models (VLMs) in textual-visual chat tasks. In this paper, we construct two new multimodal datasets: the synthetic CLEVR-ATVC dataset (620K) and the manually pictured Fruit-ATVC dataset (50K), both featuring visual and text-based inputs and outputs. Additionally, to enable the multimodal system to reject human requests (i.e., demonstrate accountability), as in language-based ChatGPT conversations, we develop and incorporate specific rules into the datasets as supervisory signals. This allows the trained VLM to provide a yes or no answer after visual and textual reasoning, accompanied by a language explanation as to why the human instruction cannot be excuted. In our method, we propose a two-state training procedure to train the image auto-encoder and auto-regressive transformer from scratch. The first state involves a discrete variational autoencoder (dVAE) to compress each image into short tokens, which are then concatenated with text tokens as a single data stream to be fed into the decoder-based transformer for generating visual re-creation and textual feedback in the second state. We provide comprehensive analyses of experimental results in terms of re-created image quality, answer accuracy, and the model behavior when faced with uncertainty and imperfect user queries. We hope our explorations and findings contribute valuable insights regarding the accountability of textual-visual generative models.

  • 2 authors
·
Mar 10, 2023

TC-LLaVA: Rethinking the Transfer from Image to Video Understanding with Temporal Considerations

Multimodal Large Language Models (MLLMs) have significantly improved performance across various image-language applications. Recently, there has been a growing interest in adapting image pre-trained MLLMs for video-related tasks. However, most efforts concentrate on enhancing the vision encoder and projector components, while the core part, Large Language Models (LLMs), remains comparatively under-explored. In this paper, we propose two strategies to enhance the model's capability in video understanding tasks by improving inter-layer attention computation in LLMs. Specifically, the first approach focuses on the enhancement of Rotary Position Embedding (RoPE) with Temporal-Aware Dual RoPE, which introduces temporal position information to strengthen the MLLM's temporal modeling capabilities while preserving the relative position relationships of both visual and text tokens. The second approach involves enhancing the Attention Mask with the Frame-wise Block Causal Attention Mask, a simple yet effective method that broadens visual token interactions within and across video frames while maintaining the causal inference mechanism. Based on these proposed methods, we adapt LLaVA for video understanding tasks, naming it Temporal-Considered LLaVA (TC-LLaVA). Our TC-LLaVA achieves new state-of-the-art performance across various video understanding benchmarks with only supervised fine-tuning (SFT) on video-related datasets.

  • 8 authors
·
Sep 4, 2024

Robust Change Captioning in Remote Sensing: SECOND-CC Dataset and MModalCC Framework

Remote sensing change captioning (RSICC) aims to describe changes between bitemporal images in natural language. Existing methods often fail under challenges like illumination differences, viewpoint changes, blur effects, leading to inaccuracies, especially in no-change regions. Moreover, the images acquired at different spatial resolutions and have registration errors tend to affect the captions. To address these issues, we introduce SECOND-CC, a novel RSICC dataset featuring high-resolution RGB image pairs, semantic segmentation maps, and diverse real-world scenarios. SECOND-CC which contains 6,041 pairs of bitemporal RS images and 30,205 sentences describing the differences between images. Additionally, we propose MModalCC, a multimodal framework that integrates semantic and visual data using advanced attention mechanisms, including Cross-Modal Cross Attention (CMCA) and Multimodal Gated Cross Attention (MGCA). Detailed ablation studies and attention visualizations further demonstrate its effectiveness and ability to address RSICC challenges. Comprehensive experiments show that MModalCC outperforms state-of-the-art RSICC methods, including RSICCformer, Chg2Cap, and PSNet with +4.6% improvement on BLEU4 score and +9.6% improvement on CIDEr score. We will make our dataset and codebase publicly available to facilitate future research at https://github.com/ChangeCapsInRS/SecondCC

  • 6 authors
·
Jan 17, 2025

True Multimodal In-Context Learning Needs Attention to the Visual Context

Multimodal Large Language Models (MLLMs), built on powerful language backbones, have enabled Multimodal In-Context Learning (MICL)-adapting to new tasks from a few multimodal demonstrations consisting of images, questions, and answers. Despite showing noticeable improvement on standard vision-language datasets, current MLLMs struggle to leverage visual information in the demonstrations. Specifically, they tend to neglect visual cues and over-rely on textual patterns, leading to mere text imitation rather than genuine multimodal adaptation. This behavior makes MICL still unimodal and largely restricts its practical utility. More importantly, this limitation is often concealed by the improved performance on tasks that do not require understanding the visual context. As a result, how to effectively enhance MICL ability and reliably evaluate the MICL performance remains underexplored. To address these issues, we first introduce Dynamic Attention Reallocation (DARA), an efficient fine-tuning strategy that encourages models to attend to the visual context by rebalancing attention across visual and textual tokens. In addition, we present TrueMICL, an MICL-dedicated dataset with both support and test sets that explicitly requires the integration of multimodal information-particularly visual content-for correct task completion. Extensive experiments demonstrate the effectiveness of our holistic solution, showcasing substantial improvements in the true multimodal in-context learning capabilities. Code and datasets are available at https://chenxshuo.github.io/true-micl-colm .

  • 8 authors
·
Jul 21, 2025 2

See What You Are Told: Visual Attention Sink in Large Multimodal Models

Large multimodal models (LMMs) "see" images by leveraging the attention mechanism between text and visual tokens in the transformer decoder. Ideally, these models should focus on key visual information relevant to the text token. However, recent findings indicate that LMMs have an extraordinary tendency to consistently allocate high attention weights to specific visual tokens, even when these tokens are irrelevant to the corresponding text. In this study, we investigate the property behind the appearance of these irrelevant visual tokens and examine their characteristics. Our findings show that this behavior arises due to the massive activation of certain hidden state dimensions, which resembles the attention sink found in language models. Hence, we refer to this phenomenon as the visual attention sink. In particular, our analysis reveals that removing the irrelevant visual sink tokens does not impact model performance, despite receiving high attention weights. Consequently, we recycle the attention to these tokens as surplus resources, redistributing the attention budget to enhance focus on the image. To achieve this, we introduce Visual Attention Redistribution (VAR), a method that redistributes attention in image-centric heads, which we identify as innately focusing on visual information. VAR can be seamlessly applied across different LMMs to improve performance on a wide range of tasks, including general vision-language tasks, visual hallucination tasks, and vision-centric tasks, all without the need for additional training, models, or inference steps. Experimental results demonstrate that VAR enables LMMs to process visual information more effectively by adjusting their internal attention mechanisms, offering a new direction to enhancing the multimodal capabilities of LMMs.

  • 4 authors
·
Mar 5, 2025

Vision Token Reduction via Attention-Driven Self-Compression for Efficient Multimodal Large Language Models

Multimodal Large Language Models (MLLMs) incur significant computational cost from processing numerous vision tokens through all LLM layers. Prior pruning methods operate either before the LLM, limiting generality due to diverse encoder-projector designs or within the LLM using heuristics that are incompatible with FlashAttention. We take a different approach: rather than identifying unimportant tokens, we treat the LLM itself as the optimal guide for compression. Observing that deeper layers naturally transmit vision-to-text information, we introduce Attention-Driven Self-Compression (ADSC), a simple, broadly applicable method that progressively reduces vision tokens using only the LLM's attention mechanism. Our method applies uniform token downsampling at selected layers, forming bottlenecks that encourage the model to reorganize and compress information into the remaining tokens. It requires no score computation, auxiliary modules, or attention modification, and remains fully compatible with FlashAttention. Applied to LLaVA-1.5, ADSC reduces FLOPs by 53.7% and peak KV-cache memory by 56.7%, while preserving 98.2% of the original model performance. Across multiple benchmarks, it outperforms prior pruning approaches in both efficiency and accuracy. Crucially, under high compression ratios, our method remains robust while heuristic-based techniques degrade sharply.

  • 5 authors
·
Feb 12

Multimodal Optimal Transport-based Co-Attention Transformer with Global Structure Consistency for Survival Prediction

Survival prediction is a complicated ordinal regression task that aims to predict the ranking risk of death, which generally benefits from the integration of histology and genomic data. Despite the progress in joint learning from pathology and genomics, existing methods still suffer from challenging issues: 1) Due to the large size of pathological images, it is difficult to effectively represent the gigapixel whole slide images (WSIs). 2) Interactions within tumor microenvironment (TME) in histology are essential for survival analysis. Although current approaches attempt to model these interactions via co-attention between histology and genomic data, they focus on only dense local similarity across modalities, which fails to capture global consistency between potential structures, i.e. TME-related interactions of histology and co-expression of genomic data. To address these challenges, we propose a Multimodal Optimal Transport-based Co-Attention Transformer framework with global structure consistency, in which optimal transport (OT) is applied to match patches of a WSI and genes embeddings for selecting informative patches to represent the gigapixel WSI. More importantly, OT-based co-attention provides a global awareness to effectively capture structural interactions within TME for survival prediction. To overcome high computational complexity of OT, we propose a robust and efficient implementation over micro-batch of WSI patches by approximating the original OT with unbalanced mini-batch OT. Extensive experiments show the superiority of our method on five benchmark datasets compared to the state-of-the-art methods. The code is released.

  • 2 authors
·
Jun 14, 2023

Mitigating Modality Prior-Induced Hallucinations in Multimodal Large Language Models via Deciphering Attention Causality

Multimodal Large Language Models (MLLMs) have emerged as a central focus in both industry and academia, but often suffer from biases introduced by visual and language priors, which can lead to multimodal hallucination. These biases arise from the visual encoder and the Large Language Model (LLM) backbone, affecting the attention mechanism responsible for aligning multimodal inputs. Existing decoding-based mitigation methods focus on statistical correlations and overlook the causal relationships between attention mechanisms and model output, limiting their effectiveness in addressing these biases. To tackle this issue, we propose a causal inference framework termed CausalMM that applies structural causal modeling to MLLMs, treating modality priors as a confounder between attention mechanisms and output. Specifically, by employing backdoor adjustment and counterfactual reasoning at both the visual and language attention levels, our method mitigates the negative effects of modality priors and enhances the alignment of MLLM's inputs and outputs, with a maximum score improvement of 65.3% on 6 VLind-Bench indicators and 164 points on MME Benchmark compared to conventional methods. Extensive experiments validate the effectiveness of our approach while being a plug-and-play solution. Our code is available at: https://github.com/The-Martyr/CausalMM

  • 6 authors
·
Oct 7, 2024

Label Dependent Attention Model for Disease Risk Prediction Using Multimodal Electronic Health Records

Disease risk prediction has attracted increasing attention in the field of modern healthcare, especially with the latest advances in artificial intelligence (AI). Electronic health records (EHRs), which contain heterogeneous patient information, are widely used in disease risk prediction tasks. One challenge of applying AI models for risk prediction lies in generating interpretable evidence to support the prediction results while retaining the prediction ability. In order to address this problem, we propose the method of jointly embedding words and labels whereby attention modules learn the weights of words from medical notes according to their relevance to the names of risk prediction labels. This approach boosts interpretability by employing an attention mechanism and including the names of prediction tasks in the model. However, its application is only limited to the handling of textual inputs such as medical notes. In this paper, we propose a label dependent attention model LDAM to 1) improve the interpretability by exploiting Clinical-BERT (a biomedical language model pre-trained on a large clinical corpus) to encode biomedically meaningful features and labels jointly; 2) extend the idea of joint embedding to the processing of time-series data, and develop a multi-modal learning framework for integrating heterogeneous information from medical notes and time-series health status indicators. To demonstrate our method, we apply LDAM to the MIMIC-III dataset to predict different disease risks. We evaluate our method both quantitatively and qualitatively. Specifically, the predictive power of LDAM will be shown, and case studies will be carried out to illustrate its interpretability.

  • 5 authors
·
Jan 18, 2022

From Narrow to Panoramic Vision: Attention-Guided Cold-Start Reshapes Multimodal Reasoning

The cold-start initialization stage plays a pivotal role in training Multimodal Large Reasoning Models (MLRMs), yet its mechanisms remain insufficiently understood. To analyze this stage, we introduce the Visual Attention Score (VAS), an attention-based metric that quantifies how much a model attends to visual tokens. We find that reasoning performance is strongly correlated with VAS (r=0.9616): models with higher VAS achieve substantially stronger multimodal reasoning. Surprisingly, multimodal cold-start fails to elevate VAS, resulting in attention distributions close to the base model, whereas text-only cold-start leads to a clear increase. We term this counter-intuitive phenomenon Lazy Attention Localization. To validate its causal role, we design training-free interventions that directly modulate attention allocation during inference, performance gains of 1-2% without any retraining. Building on these insights, we further propose Attention-Guided Visual Anchoring and Reflection (AVAR), a comprehensive cold-start framework that integrates visual-anchored data synthesis, attention-guided objectives, and visual-anchored reward shaping. Applied to Qwen2.5-VL-7B, AVAR achieves an average gain of 7.0% across 7 multimodal reasoning benchmarks. Ablation studies further confirm that each component of AVAR contributes step-wise to the overall gains. The code, data, and models are available at https://github.com/lrlbbzl/Qwen-AVAR.

Qwen Qwen
·
Mar 4 2

X2I: Seamless Integration of Multimodal Understanding into Diffusion Transformer via Attention Distillation

Text-to-image (T2I) models are well known for their ability to produce highly realistic images, while multimodal large language models (MLLMs) are renowned for their proficiency in understanding and integrating multiple modalities. However, currently there is no straightforward and efficient framework to transfer the multimodal comprehension abilities of MLLMs to T2I models to enable them to understand multimodal inputs. In this paper, we propose the X2I framework, which endows Diffusion Transformer (DiT) models with the capability to comprehend various modalities, including multilingual text, screenshot documents, images, videos, and audio. X2I is trained using merely 100K English corpus with 160 GPU hours. Building on the DiT teacher model, we adopt an innovative distillation method to extract the inference capabilities of the teacher model and design a lightweight AlignNet structure to serve as an intermediate bridge. Compared to the teacher model, X2I shows a decrease in performance degradation of less than 1\% while gaining various multimodal understanding abilities, including multilingual to image, image to image, image-text to image, video to image, audio to image, and utilizing creative fusion to enhance imagery. Furthermore, it is applicable for LoRA training in the context of image-text to image generation, filling a void in the industry in this area. We further design a simple LightControl to enhance the fidelity of instructional image editing. Finally, extensive experiments demonstrate the effectiveness, efficiency, multifunctionality, and transferability of our X2I. The open-source code and checkpoints for X2I can be found at the following link: https://github.com/OPPO-Mente-Lab/X2I.

  • 6 authors
·
Mar 8, 2025

GPT-4 Enhanced Multimodal Grounding for Autonomous Driving: Leveraging Cross-Modal Attention with Large Language Models

In the field of autonomous vehicles (AVs), accurately discerning commander intent and executing linguistic commands within a visual context presents a significant challenge. This paper introduces a sophisticated encoder-decoder framework, developed to address visual grounding in AVs.Our Context-Aware Visual Grounding (CAVG) model is an advanced system that integrates five core encoders-Text, Image, Context, and Cross-Modal-with a Multimodal decoder. This integration enables the CAVG model to adeptly capture contextual semantics and to learn human emotional features, augmented by state-of-the-art Large Language Models (LLMs) including GPT-4. The architecture of CAVG is reinforced by the implementation of multi-head cross-modal attention mechanisms and a Region-Specific Dynamic (RSD) layer for attention modulation. This architectural design enables the model to efficiently process and interpret a range of cross-modal inputs, yielding a comprehensive understanding of the correlation between verbal commands and corresponding visual scenes. Empirical evaluations on the Talk2Car dataset, a real-world benchmark, demonstrate that CAVG establishes new standards in prediction accuracy and operational efficiency. Notably, the model exhibits exceptional performance even with limited training data, ranging from 50% to 75% of the full dataset. This feature highlights its effectiveness and potential for deployment in practical AV applications. Moreover, CAVG has shown remarkable robustness and adaptability in challenging scenarios, including long-text command interpretation, low-light conditions, ambiguous command contexts, inclement weather conditions, and densely populated urban environments. The code for the proposed model is available at our Github.

  • 7 authors
·
Dec 6, 2023

An Efficient Multimodal Learning Framework to Comprehend Consumer Preferences Using BERT and Cross-Attention

Today, the acquisition of various behavioral log data has enabled deeper understanding of customer preferences and future behaviors in the marketing field. In particular, multimodal deep learning has achieved highly accurate predictions by combining multiple types of data. Many of these studies utilize with feature fusion to construct multimodal models, which combines extracted representations from each modality. However, since feature fusion treats information from each modality equally, it is difficult to perform flexible analysis such as the attention mechanism that has been used extensively in recent years. Therefore, this study proposes a context-aware multimodal deep learning model that combines Bidirectional Encoder Representations from Transformers (BERT) and cross-attention Transformer, which dynamically changes the attention of deep-contextualized word representations based on background information such as consumer demographic and lifestyle variables. We conduct a comprehensive analysis and demonstrate the effectiveness of our model by comparing it with six reference models in three categories using behavioral logs stored on an online platform. In addition, we present an efficient multimodal learning method by comparing the learning efficiency depending on the optimizers and the prediction accuracy depending on the number of tokens in the text data.

  • 1 authors
·
May 12, 2024

Multimodal Fake News Detection via CLIP-Guided Learning

Multimodal fake news detection has attracted many research interests in social forensics. Many existing approaches introduce tailored attention mechanisms to guide the fusion of unimodal features. However, how the similarity of these features is calculated and how it will affect the decision-making process in FND are still open questions. Besides, the potential of pretrained multi-modal feature learning models in fake news detection has not been well exploited. This paper proposes a FND-CLIP framework, i.e., a multimodal Fake News Detection network based on Contrastive Language-Image Pretraining (CLIP). Given a targeted multimodal news, we extract the deep representations from the image and text using a ResNet-based encoder, a BERT-based encoder and two pair-wise CLIP encoders. The multimodal feature is a concatenation of the CLIP-generated features weighted by the standardized cross-modal similarity of the two modalities. The extracted features are further processed for redundancy reduction before feeding them into the final classifier. We introduce a modality-wise attention module to adaptively reweight and aggregate the features. We have conducted extensive experiments on typical fake news datasets. The results indicate that the proposed framework has a better capability in mining crucial features for fake news detection. The proposed FND-CLIP can achieve better performances than previous works, i.e., 0.7\%, 6.8\% and 1.3\% improvements in overall accuracy on Weibo, Politifact and Gossipcop, respectively. Besides, we justify that CLIP-based learning can allow better flexibility on multimodal feature selection.

  • 5 authors
·
May 27, 2022

mmE5: Improving Multimodal Multilingual Embeddings via High-quality Synthetic Data

Multimodal embedding models have gained significant attention for their ability to map data from different modalities, such as text and images, into a unified representation space. However, the limited labeled multimodal data often hinders embedding performance. Recent approaches have leveraged data synthesis to address this problem, yet the quality of synthetic data remains a critical bottleneck. In this work, we identify three criteria for high-quality synthetic multimodal data. First, broad scope ensures that the generated data covers diverse tasks and modalities, making it applicable to various downstream scenarios. Second, robust cross-modal alignment makes different modalities semantically consistent. Third, high fidelity ensures that the synthetic data maintains realistic details to enhance its reliability. Guided by these principles, we synthesize datasets that: (1) cover a wide range of tasks, modality combinations, and languages, (2) are generated via a deep thinking process within a single pass of a multimodal large language model, and (3) incorporate real-world images with accurate and relevant texts, ensuring fidelity through self-evaluation and refinement. Leveraging these high-quality synthetic and labeled datasets, we train a multimodal multilingual E5 model mmE5. Extensive experiments demonstrate that mmE5 achieves state-of-the-art performance on the MMEB Benchmark and superior multilingual performance on the XTD benchmark. Our codes, datasets and models are released in https://github.com/haon-chen/mmE5.

  • 7 authors
·
Feb 12, 2025 2

Mitigating Attention Sinks and Massive Activations in Audio-Visual Speech Recognition with LLMS

Large language models (LLMs) have recently advanced auditory speech recognition (ASR), visual speech recognition (VSR), and audio-visual speech recognition (AVSR). However, understanding of their internal dynamics under fine-tuning remains limited. In natural language processing, recent work has revealed attention sinks, tokens that attract disproportionately high attention, and associated massive activations in which some features of sink tokens exhibit huge activation in LLMs. In this work, we are the first to study these phenomena in multimodal speech recognition. Through a detailed analysis of audio-visual LLMs, we identify attention sinks and massive activations not only at the BOS token but also at intermediate low-semantic tokens across ASR, VSR, and AVSR. We show that massive activations originate in the MLP layers and correspond to fixed feature indices across all sink tokens. We further show that intermediate sink tokens exhibit high cosine similarity to the BOS token, thereby amplifying attention and activation. Building on these insights, we introduce a simple decorrelation loss that reduces cosine similarity between BOS and other tokens, effectively mitigating intermediate sinks and massive activations. Furthermore, our method improves word error rate (WER) under high audio-visual feature downsampling while remaining stable at lower downsampling rates.

LinMU: Multimodal Understanding Made Linear

Modern Vision-Language Models (VLMs) achieve impressive performance but are limited by the quadratic complexity of self-attention, which prevents their deployment on edge devices and makes their understanding of high-resolution images and long-context videos prohibitively expensive. To address this challenge, we introduce LinMU (Linear-complexity Multimodal Understanding), a VLM design that achieves linear complexity without using any quadratic-complexity modules while maintaining the performance of global-attention-based VLMs. LinMU replaces every self-attention layer in the VLM with the M-MATE block: a dual-branch module that combines a bidirectional state-space model for global context (Flex-MA branch) with localized Swin-style window attention (Local-Swin branch) for adjacent correlations. To transform a pre-trained VLM into the LinMU architecture, we propose a three-stage distillation framework that (i) initializes both branches with self-attention weights and trains the Flex-MA branch alone, (ii) unfreezes the Local-Swin branch and fine-tunes it jointly with the Flex-MA branch, and (iii) unfreezes the remaining blocks and fine-tunes them using LoRA adapters, while regressing on hidden states and token-level logits of the frozen VLM teacher. On MMMU, TextVQA, LongVideoBench, Video-MME, and other benchmarks, LinMU matches the performance of teacher models, yet reduces Time-To-First-Token (TTFT) by up to 2.7times and improves token throughput by up to 9.0times on minute-length videos. Ablations confirm the importance of each distillation stage and the necessity of the two branches of the M-MATE block. The proposed framework demonstrates that state-of-the-art multimodal reasoning can be achieved without quadratic attention, thus opening up avenues for long-context VLMs that can deal with high-resolution images and long videos.

  • 2 authors
·
Jan 3

Semantic Item Graph Enhancement for Multimodal Recommendation

Multimodal recommendation systems have attracted increasing attention for their improved performance by leveraging items' multimodal information. Prior methods often build modality-specific item-item semantic graphs from raw modality features and use them as supplementary structures alongside the user-item interaction graph to enhance user preference learning. However, these semantic graphs suffer from semantic deficiencies, including (1) insufficient modeling of collaborative signals among items and (2) structural distortions introduced by noise in raw modality features, ultimately compromising performance. To address these issues, we first extract collaborative signals from the interaction graph and infuse them into each modality-specific item semantic graph to enhance semantic modeling. Then, we design a modulus-based personalized embedding perturbation mechanism that injects perturbations with modulus-guided personalized intensity into embeddings to generate contrastive views. This enables the model to learn noise-robust representations through contrastive learning, thereby reducing the effect of structural noise in semantic graphs. Besides, we propose a dual representation alignment mechanism that first aligns multiple semantic representations via a designed Anchor-based InfoNCE loss using behavior representations as anchors, and then aligns behavior representations with the fused semantics by standard InfoNCE, to ensure representation consistency. Extensive experiments on four benchmark datasets validate the effectiveness of our framework.

  • 5 authors
·
Aug 8, 2025

AlignDiT: Multimodal Aligned Diffusion Transformer for Synchronized Speech Generation

In this paper, we address the task of multimodal-to-speech generation, which aims to synthesize high-quality speech from multiple input modalities: text, video, and reference audio. This task has gained increasing attention due to its wide range of applications, such as film production, dubbing, and virtual avatars. Despite recent progress, existing methods still suffer from limitations in speech intelligibility, audio-video synchronization, speech naturalness, and voice similarity to the reference speaker. To address these challenges, we propose AlignDiT, a multimodal Aligned Diffusion Transformer that generates accurate, synchronized, and natural-sounding speech from aligned multimodal inputs. Built upon the in-context learning capability of the DiT architecture, AlignDiT explores three effective strategies to align multimodal representations. Furthermore, we introduce a novel multimodal classifier-free guidance mechanism that allows the model to adaptively balance information from each modality during speech synthesis. Extensive experiments demonstrate that AlignDiT significantly outperforms existing methods across multiple benchmarks in terms of quality, synchronization, and speaker similarity. Moreover, AlignDiT exhibits strong generalization capability across various multimodal tasks, such as video-to-speech synthesis and visual forced alignment, consistently achieving state-of-the-art performance. The demo page is available at https://mm.kaist.ac.kr/projects/AlignDiT.

  • 5 authors
·
Apr 29, 2025

ITCFN: Incomplete Triple-Modal Co-Attention Fusion Network for Mild Cognitive Impairment Conversion Prediction

Alzheimer's disease (AD) is a common neurodegenerative disease among the elderly. Early prediction and timely intervention of its prodromal stage, mild cognitive impairment (MCI), can decrease the risk of advancing to AD. Combining information from various modalities can significantly improve predictive accuracy. However, challenges such as missing data and heterogeneity across modalities complicate multimodal learning methods as adding more modalities can worsen these issues. Current multimodal fusion techniques often fail to adapt to the complexity of medical data, hindering the ability to identify relationships between modalities. To address these challenges, we propose an innovative multimodal approach for predicting MCI conversion, focusing specifically on the issues of missing positron emission tomography (PET) data and integrating diverse medical information. The proposed incomplete triple-modal MCI conversion prediction network is tailored for this purpose. Through the missing modal generation module, we synthesize the missing PET data from the magnetic resonance imaging and extract features using specifically designed encoders. We also develop a channel aggregation module and a triple-modal co-attention fusion module to reduce feature redundancy and achieve effective multimodal data fusion. Furthermore, we design a loss function to handle missing modality issues and align cross-modal features. These components collectively harness multimodal data to boost network performance. Experimental results on the ADNI1 and ADNI2 datasets show that our method significantly surpasses existing unimodal and other multimodal models. Our code is available at https://github.com/justinhxy/ITFC.

  • 11 authors
·
Jan 20, 2025

MLLM-as-a-Judge: Assessing Multimodal LLM-as-a-Judge with Vision-Language Benchmark

Multimodal Large Language Models (MLLMs) have gained significant attention recently, showing remarkable potential in artificial general intelligence. However, assessing the utility of MLLMs presents considerable challenges, primarily due to the absence of multimodal benchmarks that align with human preferences. Drawing inspiration from the concept of LLM-as-a-Judge within LLMs, this paper introduces a novel benchmark, termed MLLM-as-a-Judge, to assess the ability of MLLMs in assisting judges across diverse modalities, encompassing three distinct tasks: Scoring Evaluation, Pair Comparison, and Batch Ranking. Our study reveals that, while MLLMs demonstrate remarkable human-like discernment in Pair Comparison, there is a significant divergence from human preferences in Scoring Evaluation and Batch Ranking. Furthermore, a closer examination reveals persistent challenges in the judgment capacities of LLMs, including diverse biases, hallucinatory responses, and inconsistencies in judgment, even in advanced models such as GPT-4V. These findings emphasize the pressing need for enhancements and further research efforts to be undertaken before regarding MLLMs as fully reliable evaluators. In light of this, we advocate for additional efforts dedicated to supporting the continuous development within the domain of MLLM functioning as judges. The code and dataset are publicly available at our project homepage: https://mllm-judge.github.io/.

  • 10 authors
·
Feb 7, 2024

Sentiment Word Aware Multimodal Refinement for Multimodal Sentiment Analysis with ASR Errors

Multimodal sentiment analysis has attracted increasing attention and lots of models have been proposed. However, the performance of the state-of-the-art models decreases sharply when they are deployed in the real world. We find that the main reason is that real-world applications can only access the text outputs by the automatic speech recognition (ASR) models, which may be with errors because of the limitation of model capacity. Through further analysis of the ASR outputs, we find that in some cases the sentiment words, the key sentiment elements in the textual modality, are recognized as other words, which makes the sentiment of the text change and hurts the performance of multimodal sentiment models directly. To address this problem, we propose the sentiment word aware multimodal refinement model (SWRM), which can dynamically refine the erroneous sentiment words by leveraging multimodal sentiment clues. Specifically, we first use the sentiment word position detection module to obtain the most possible position of the sentiment word in the text and then utilize the multimodal sentiment word refinement module to dynamically refine the sentiment word embeddings. The refined embeddings are taken as the textual inputs of the multimodal feature fusion module to predict the sentiment labels. We conduct extensive experiments on the real-world datasets including MOSI-Speechbrain, MOSI-IBM, and MOSI-iFlytek and the results demonstrate the effectiveness of our model, which surpasses the current state-of-the-art models on three datasets. Furthermore, our approach can be adapted for other multimodal feature fusion models easily. Data and code are available at https://github.com/albertwy/SWRM.

  • 7 authors
·
Mar 1, 2022

HiRED: Attention-Guided Token Dropping for Efficient Inference of High-Resolution Vision-Language Models in Resource-Constrained Environments

High-resolution Vision-Language Models (VLMs) have been widely used in multimodal tasks to enhance accuracy by preserving detailed image information. However, these models often generate excessive visual tokens due to encoding multiple partitions of the input image. Processing these excessive visual tokens is computationally challenging, especially in resource-constrained environments with commodity GPUs. To support high-resolution images while meeting resource constraints, we propose High-Resolution Early Dropping (HiRED), a token-dropping scheme that operates within a fixed token budget before the Large Language Model (LLM) stage. HiRED can be integrated with existing high-resolution VLMs in a plug-and-play manner, as it requires no additional training while still maintaining superior accuracy. We strategically use the vision encoder's attention in the initial layers to assess the visual content of each image partition and allocate the token budget accordingly. Then, using the attention in the final layer, we select the most important visual tokens from each partition within the allocated budget, dropping the rest. Empirically, when applied to LLaVA-Next-7B on NVIDIA TESLA P40 GPU, HiRED with a 20% token budget increases token generation throughput by 4.7, reduces first-token generation latency by 15 seconds, and saves 2.3 GB of GPU memory for a single inference.

  • 6 authors
·
Aug 20, 2024 2

SATORI-R1: Incentivizing Multimodal Reasoning with Spatial Grounding and Verifiable Rewards

DeepSeek-R1 has demonstrated powerful reasoning capabilities in the text domain through stable reinforcement learning (RL). Recently, in the multimodal domain, works have begun to directly apply RL to generate R1-like free-form reasoning for Visual Question Answering (VQA) tasks. However, multimodal tasks share an intrinsically different nature from textual tasks, which heavily rely on the understanding of the input image to solve the problem. Therefore, such free-form reasoning faces two critical limitations in the VQA task: (1) Extended reasoning chains diffuse visual focus away from task-critical regions, degrading answer accuracy. (2) Unverifiable intermediate steps amplify policy-gradient variance and computational costs overhead. To address these issues, in this paper, we introduce SATORI (Spatially Anchored Task Optimization with ReInforcement Learning), which decomposes VQA into three verifiable stages, including global image captioning, region localization, and answer prediction, each supplying explicit reward signals. Furthermore, we also introduce VQA-Verify, a 12k dataset annotated with answer-aligned captions and bounding-boxes to facilitate training. Experiments demonstrate consistent performance improvements across seven VQA benchmarks, achieving up to 15.7% improvement in accuracy in accuracy compared to the R1-like baseline. Our analysis of the attention map confirms enhanced focus on critical regions, which brings improvements in accuracy. Our code is available at https://github.com/justairr/SATORI-R1.

  • 4 authors
·
May 25, 2025 2

Multimodal Sleep Stage and Sleep Apnea Classification Using Vision Transformer: A Multitask Explainable Learning Approach

Sleep is an essential component of human physiology, contributing significantly to overall health and quality of life. Accurate sleep staging and disorder detection are crucial for assessing sleep quality. Studies in the literature have proposed PSG-based approaches and machine-learning methods utilizing single-modality signals. However, existing methods often lack multimodal, multilabel frameworks and address sleep stages and disorders classification separately. In this paper, we propose a 1D-Vision Transformer for simultaneous classification of sleep stages and sleep disorders. Our method exploits the sleep disorders' correlation with specific sleep stage patterns and performs a simultaneous identification of a sleep stage and sleep disorder. The model is trained and tested using multimodal-multilabel sensory data (including photoplethysmogram, respiratory flow, and respiratory effort signals). The proposed method shows an overall accuracy (cohen's Kappa) of 78% (0.66) for five-stage sleep classification and 74% (0.58) for sleep apnea classification. Moreover, we analyzed the encoder attention weights to clarify our models' predictions and investigate the influence different features have on the models' outputs. The result shows that identified patterns, such as respiratory troughs and peaks, make a higher contribution to the final classification process.

  • 6 authors
·
Feb 18, 2025

SAISA: Towards Multimodal Large Language Models with Both Training and Inference Efficiency

Multimodal Large Language Models (MLLMs) mainly fall into two architectures, each involving a trade-off between training and inference efficiency: embedding space alignment (e.g., LLaVA-1.5) is inefficient during inference, while cross-attention space alignment (e.g., Flamingo) is inefficient in training. In this paper, we compare these two architectures and identify the key factors for building efficient MLLMs. A primary difference between them lies in how attention is applied to visual tokens, particularly in their interactions with each other. To investigate whether attention among visual tokens is necessary, we propose a new self-attention mechanism, NAAViT (No Attention Among Visual Tokens), which eliminates this type of attention. Our pilot experiment on LLaVA-1.5 shows that attention among visual tokens is highly redundant. Based on these insights, we introduce SAISA (Self-Attention Input Space Alignment), a novel architecture that enhance both training and inference efficiency. SAISA directly aligns visual features with the input spaces of NAAViT self-attention blocks, reducing computational overhead in both self-attention blocks and feed-forward networks (FFNs). Using the same configuration as LLaVA-1.5, SAISA reduces inference FLOPs by 66\% and training budget by 26\%, while achieving superior performance in terms of accuracy. Comprehensive ablation studies further validate the effectiveness of SAISA across various LLMs and visual encoders. The code and model will be publicly available at https://github.com/icip-cas/SAISA.

  • 7 authors
·
Feb 4, 2025

The Evolution of Multimodal Model Architectures

This work uniquely identifies and characterizes four prevalent multimodal model architectural patterns in the contemporary multimodal landscape. Systematically categorizing models by architecture type facilitates monitoring of developments in the multimodal domain. Distinct from recent survey papers that present general information on multimodal architectures, this research conducts a comprehensive exploration of architectural details and identifies four specific architectural types. The types are distinguished by their respective methodologies for integrating multimodal inputs into the deep neural network model. The first two types (Type A and B) deeply fuses multimodal inputs within the internal layers of the model, whereas the following two types (Type C and D) facilitate early fusion at the input stage. Type-A employs standard cross-attention, whereas Type-B utilizes custom-designed layers for modality fusion within the internal layers. On the other hand, Type-C utilizes modality-specific encoders, while Type-D leverages tokenizers to process the modalities at the model's input stage. The identified architecture types aid the monitoring of any-to-any multimodal model development. Notably, Type-C and Type-D are currently favored in the construction of any-to-any multimodal models. Type-C, distinguished by its non-tokenizing multimodal model architecture, is emerging as a viable alternative to Type-D, which utilizes input-tokenizing techniques. To assist in model selection, this work highlights the advantages and disadvantages of each architecture type based on data and compute requirements, architecture complexity, scalability, simplification of adding modalities, training objectives, and any-to-any multimodal generation capability.

  • 4 authors
·
May 28, 2024

LMM-Det: Make Large Multimodal Models Excel in Object Detection

Large multimodal models (LMMs) have garnered wide-spread attention and interest within the artificial intelligence research and industrial communities, owing to their remarkable capability in multimodal understanding, reasoning, and in-context learning, among others. While LMMs have demonstrated promising results in tackling multimodal tasks like image captioning, visual question answering, and visual grounding, the object detection capabilities of LMMs exhibit a significant gap compared to specialist detectors. To bridge the gap, we depart from the conventional methods of integrating heavy detectors with LMMs and propose LMM-Det, a simple yet effective approach that leverages a Large Multimodal Model for vanilla object Detection without relying on specialized detection modules. Specifically, we conduct a comprehensive exploratory analysis when a large multimodal model meets with object detection, revealing that the recall rate degrades significantly compared with specialist detection models. To mitigate this, we propose to increase the recall rate by introducing data distribution adjustment and inference optimization tailored for object detection. We re-organize the instruction conversations to enhance the object detection capabilities of large multimodal models. We claim that a large multimodal model possesses detection capability without any extra detection modules. Extensive experiments support our claim and show the effectiveness of the versatile LMM-Det. The datasets, models, and codes are available at https://github.com/360CVGroup/LMM-Det.

  • 5 authors
·
Jul 24, 2025

Generate to Ground: Multimodal Text Conditioning Boosts Phrase Grounding in Medical Vision-Language Models

Phrase grounding, i.e., mapping natural language phrases to specific image regions, holds significant potential for disease localization in medical imaging through clinical reports. While current state-of-the-art methods rely on discriminative, self-supervised contrastive models, we demonstrate that generative text-to-image diffusion models, leveraging cross-attention maps, can achieve superior zero-shot phrase grounding performance. Contrary to prior assumptions, we show that fine-tuning diffusion models with a frozen, domain-specific language model, such as CXR-BERT, substantially outperforms domain-agnostic counterparts. This setup achieves remarkable improvements, with mIoU scores doubling those of current discriminative methods. These findings highlight the underexplored potential of generative models for phrase grounding tasks. To further enhance performance, we introduce Bimodal Bias Merging (BBM), a novel post-processing technique that aligns text and image biases to identify regions of high certainty. BBM refines cross-attention maps, achieving even greater localization accuracy. Our results establish generative approaches as a more effective paradigm for phrase grounding in the medical imaging domain, paving the way for more robust and interpretable applications in clinical practice. The source code and model weights are available at https://github.com/Felix-012/generate_to_ground.

  • 3 authors
·
Jul 16, 2025

A Culturally-diverse Multilingual Multimodal Video Benchmark & Model

Large multimodal models (LMMs) have recently gained attention due to their effectiveness to understand and generate descriptions of visual content. Most existing LMMs are in English language. While few recent works explore multilingual image LMMs, to the best of our knowledge, moving beyond the English language for cultural and linguistic inclusivity is yet to be investigated in the context of video LMMs. In pursuit of more inclusive video LMMs, we introduce a multilingual Video LMM benchmark, named ViMUL-Bench, to evaluate Video LMMs across 14 languages, including both low- and high-resource languages: English, Chinese, Spanish, French, German, Hindi, Arabic, Russian, Bengali, Urdu, Sinhala, Tamil, Swedish, and Japanese. Our ViMUL-Bench is designed to rigorously test video LMMs across 15 categories including eight culturally diverse categories, ranging from lifestyles and festivals to foods and rituals and from local landmarks to prominent cultural personalities. ViMUL-Bench comprises both open-ended (short and long-form) and multiple-choice questions spanning various video durations (short, medium, and long) with 8k samples that are manually verified by native language speakers. In addition, we also introduce a machine translated multilingual video training set comprising 1.2 million samples and develop a simple multilingual video LMM, named ViMUL, that is shown to provide a better tradeoff between high-and low-resource languages for video understanding. We hope our ViMUL-Bench and multilingual video LMM along with a large-scale multilingual video training set will help ease future research in developing cultural and linguistic inclusive multilingual video LMMs. Our proposed benchmark, video LMM and training data will be publicly released at https://mbzuai-oryx.github.io/ViMUL/.

  • 29 authors
·
Jun 8, 2025

MDPE: A Multimodal Deception Dataset with Personality and Emotional Characteristics

Deception detection has garnered increasing attention in recent years due to the significant growth of digital media and heightened ethical and security concerns. It has been extensively studied using multimodal methods, including video, audio, and text. In addition, individual differences in deception production and detection are believed to play a crucial role.Although some studies have utilized individual information such as personality traits to enhance the performance of deception detection, current systems remain limited, partly due to a lack of sufficient datasets for evaluating performance. To address this issue, we introduce a multimodal deception dataset MDPE. Besides deception features, this dataset also includes individual differences information in personality and emotional expression characteristics. It can explore the impact of individual differences on deception behavior. It comprises over 104 hours of deception and emotional videos from 193 subjects. Furthermore, we conducted numerous experiments to provide valuable insights for future deception detection research. MDPE not only supports deception detection, but also provides conditions for tasks such as personality recognition and emotion recognition, and can even study the relationships between them. We believe that MDPE will become a valuable resource for promoting research in the field of affective computing.

  • 14 authors
·
Jul 16, 2024

Hallucination of Multimodal Large Language Models: A Survey

This survey presents a comprehensive analysis of the phenomenon of hallucination in multimodal large language models (MLLMs), also known as Large Vision-Language Models (LVLMs), which have demonstrated significant advancements and remarkable abilities in multimodal tasks. Despite these promising developments, MLLMs often generate outputs that are inconsistent with the visual content, a challenge known as hallucination, which poses substantial obstacles to their practical deployment and raises concerns regarding their reliability in real-world applications. This problem has attracted increasing attention, prompting efforts to detect and mitigate such inaccuracies. We review recent advances in identifying, evaluating, and mitigating these hallucinations, offering a detailed overview of the underlying causes, evaluation benchmarks, metrics, and strategies developed to address this issue. Additionally, we analyze the current challenges and limitations, formulating open questions that delineate potential pathways for future research. By drawing the granular classification and landscapes of hallucination causes, evaluation benchmarks, and mitigation methods, this survey aims to deepen the understanding of hallucinations in MLLMs and inspire further advancements in the field. Through our thorough and in-depth review, we contribute to the ongoing dialogue on enhancing the robustness and reliability of MLLMs, providing valuable insights and resources for researchers and practitioners alike. Resources are available at: https://github.com/showlab/Awesome-MLLM-Hallucination.

  • 7 authors
·
Apr 29, 2024

MSVD-Indonesian: A Benchmark for Multimodal Video-Text Tasks in Indonesian

Multimodal learning on video and text data has been receiving growing attention from many researchers in various research tasks, including text-to-video retrieval, video-to-text retrieval, and video captioning. Although many algorithms have been proposed for those challenging tasks, most of them are developed on English language datasets. Despite Indonesian being one of the most spoken languages in the world, the research progress on the multimodal video-text with Indonesian sentences is still under-explored, likely due to the absence of the public benchmark dataset. To address this issue, we construct the first public Indonesian video-text dataset by translating English sentences from the MSVD dataset to Indonesian sentences. Using our dataset, we then train neural network models which were developed for the English video-text dataset on three tasks, i.e., text-to-video retrieval, video-to-text retrieval, and video captioning. The recent neural network-based approaches to video-text tasks often utilized a feature extractor that is primarily pretrained on an English vision-language dataset. Since the availability of the pretraining resources with Indonesian sentences is relatively limited, the applicability of those approaches to our dataset is still questionable. To overcome the lack of pretraining resources, we apply cross-lingual transfer learning by utilizing the feature extractors pretrained on the English dataset, and we then fine-tune the models on our Indonesian dataset. Our experimental results show that this approach can help to improve the performance for the three tasks on all metrics. Finally, we discuss potential future works using our dataset, inspiring further research in the Indonesian multimodal video-text tasks. We believe that our dataset and our experimental results could provide valuable contributions to the community. Our dataset is available on GitHub.

  • 1 authors
·
Jun 20, 2023

MolFM: A Multimodal Molecular Foundation Model

Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount significance in facilitating biomedical research. However, existing multimodal molecular foundation models exhibit limitations in capturing intricate connections between molecular structures and texts, and more importantly, none of them attempt to leverage a wealth of molecular expertise derived from knowledge graphs. In this study, we introduce MolFM, a multimodal molecular foundation model designed to facilitate joint representation learning from molecular structures, biomedical texts, and knowledge graphs. We propose cross-modal attention between atoms of molecular structures, neighbors of molecule entities and semantically related texts to facilitate cross-modal comprehension. We provide theoretical analysis that our cross-modal pre-training captures local and global molecular knowledge by minimizing the distance in the feature space between different modalities of the same molecule, as well as molecules sharing similar structures or functions. MolFM achieves state-of-the-art performance on various downstream tasks. On cross-modal retrieval, MolFM outperforms existing models with 12.13% and 5.04% absolute gains under the zero-shot and fine-tuning settings, respectively. Furthermore, qualitative analysis showcases MolFM's implicit ability to provide grounding from molecular substructures and knowledge graphs. Code and models are available on https://github.com/BioFM/OpenBioMed.

  • 5 authors
·
Jun 6, 2023