new

Get trending papers in your email inbox!

Subscribe

Daily Papers

byAK and the research community

Jan 13

Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialogue

Recent advances in Large Language Models (LLMs) have achieved remarkable breakthroughs in understanding and responding to user intents. However, their performance lag behind general use cases in some expertise domains, such as Chinese medicine. Existing efforts to incorporate Chinese medicine into LLMs rely on Supervised Fine-Tuning (SFT) with single-turn and distilled dialogue data. These models lack the ability for doctor-like proactive inquiry and multi-turn comprehension and cannot align responses with experts' intentions. In this work, we introduce Zhongjing, the first Chinese medical LLaMA-based LLM that implements an entire training pipeline from continuous pre-training, SFT, to Reinforcement Learning from Human Feedback (RLHF). Additionally, we construct a Chinese multi-turn medical dialogue dataset of 70,000 authentic doctor-patient dialogues, CMtMedQA, which significantly enhances the model's capability for complex dialogue and proactive inquiry initiation. We also define a refined annotation rule and evaluation criteria given the unique characteristics of the biomedical domain. Extensive experimental results show that Zhongjing outperforms baselines in various capacities and matches the performance of ChatGPT in some abilities, despite the 100x parameters. Ablation studies also demonstrate the contributions of each component: pre-training enhances medical knowledge, and RLHF further improves instruction-following ability and safety. Our code, datasets, and models are available at https://github.com/SupritYoung/Zhongjing.

  • 7 authors
·
Aug 7, 2023

Teaching Language Models To Gather Information Proactively

Large language models (LLMs) are increasingly expected to function as collaborative partners, engaging in back-and-forth dialogue to solve complex, ambiguous problems. However, current LLMs often falter in real-world settings, defaulting to passive responses or narrow clarifications when faced with incomplete or under-specified prompts, falling short of proactively gathering the missing information that is crucial for high-quality solutions. In this work, we introduce a new task paradigm: proactive information gathering, where LLMs must identify gaps in the provided context and strategically elicit implicit user knowledge through targeted questions. To systematically study and train this capability, we design a scalable framework that generates partially specified, real-world tasks, masking key information and simulating authentic ambiguity. Within this setup, our core innovation is a reinforcement finetuning strategy that rewards questions that elicit genuinely new, implicit user information -- such as hidden domain expertise or fine-grained requirements -- that would otherwise remain unspoken. Experiments demonstrate that our trained Qwen-2.5-7B model significantly outperforms o3-mini by 18% on automatic evaluation metrics. More importantly, human evaluation reveals that clarification questions and final outlines generated by our model are favored by human annotators by 42% and 28% respectively. Together, these results highlight the value of proactive clarification in elevating LLMs from passive text generators to genuinely collaborative thought partners.

  • 7 authors
·
Jul 28, 2025

Proactive Agent: Shifting LLM Agents from Reactive Responses to Active Assistance

Agents powered by large language models have shown remarkable abilities in solving complex tasks. However, most agent systems remain reactive, limiting their effectiveness in scenarios requiring foresight and autonomous decision-making. In this paper, we tackle the challenge of developing proactive agents capable of anticipating and initiating tasks without explicit human instructions. We propose a novel data-driven approach for this problem. Firstly, we collect real-world human activities to generate proactive task predictions. These predictions are then labeled by human annotators as either accepted or rejected. The labeled data is used to train a reward model that simulates human judgment and serves as an automatic evaluator of the proactiveness of LLM agents. Building on this, we develop a comprehensive data generation pipeline to create a diverse dataset, ProactiveBench, containing 6,790 events. Finally, we demonstrate that fine-tuning models with the proposed ProactiveBench can significantly elicit the proactiveness of LLM agents. Experimental results show that our fine-tuned model achieves an F1-Score of 66.47% in proactively offering assistance, outperforming all open-source and close-source models. These results highlight the potential of our method in creating more proactive and effective agent systems, paving the way for future advancements in human-agent collaboration.

  • 15 authors
·
Oct 16, 2024

ContextAgent: Context-Aware Proactive LLM Agents with Open-World Sensory Perceptions

Recent advances in Large Language Models (LLMs) have propelled intelligent agents from reactive responses to proactive support. While promising, existing proactive agents either rely exclusively on observations from enclosed environments (e.g., desktop UIs) with direct LLM inference or employ rule-based proactive notifications, leading to suboptimal user intent understanding and limited functionality for proactive service. In this paper, we introduce ContextAgent, the first context-aware proactive agent that incorporates extensive sensory contexts to enhance the proactive capabilities of LLM agents. ContextAgent first extracts multi-dimensional contexts from massive sensory perceptions on wearables (e.g., video and audio) to understand user intentions. ContextAgent then leverages the sensory contexts and the persona contexts from historical data to predict the necessity for proactive services. When proactive assistance is needed, ContextAgent further automatically calls the necessary tools to assist users unobtrusively. To evaluate this new task, we curate ContextAgentBench, the first benchmark for evaluating context-aware proactive LLM agents, covering 1,000 samples across nine daily scenarios and twenty tools. Experiments on ContextAgentBench show that ContextAgent outperforms baselines by achieving up to 8.5% and 6.0% higher accuracy in proactive predictions and tool calling, respectively. We hope our research can inspire the development of more advanced, human-centric, proactive AI assistants.

  • 10 authors
·
May 20, 2025

MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoning

Users typically engage with LLMs interactively, yet most existing benchmarks evaluate them in a static, single-turn format, posing reliability concerns in interactive scenarios. We identify a key obstacle towards reliability: LLMs are trained to answer any question, even with incomplete context or insufficient knowledge. In this paper, we propose to change the static paradigm to an interactive one, develop systems that proactively ask questions to gather more information and respond reliably, and introduce an benchmark - MediQ - to evaluate question-asking ability in LLMs. MediQ simulates clinical interactions consisting of a Patient System and an adaptive Expert System; with potentially incomplete initial information, the Expert refrains from making diagnostic decisions when unconfident, and instead elicits missing details via follow-up questions. We provide a pipeline to convert single-turn medical benchmarks into an interactive format. Our results show that directly prompting state-of-the-art LLMs to ask questions degrades performance, indicating that adapting LLMs to proactive information-seeking settings is nontrivial. We experiment with abstention strategies to better estimate model confidence and decide when to ask questions, improving diagnostic accuracy by 22.3%; however, performance still lags compared to an (unrealistic in practice) upper bound with complete information upfront. Further analyses show improved interactive performance with filtering irrelevant contexts and reformatting conversations. Overall, we introduce a novel problem towards LLM reliability, an interactive MediQ benchmark and a novel question-asking system, and highlight directions to extend LLMs' information-seeking abilities in critical domains.

  • 7 authors
·
Jun 2, 2024

Plug-and-Play Policy Planner for Large Language Model Powered Dialogue Agents

Proactive dialogues serve as a practical yet challenging dialogue problem in the era of large language models (LLMs), where the dialogue policy planning is the key to improving the proactivity of LLMs. Most existing studies enable the dialogue policy planning of LLMs using various prompting schemes or iteratively enhance this capability in handling the given case with verbal AI feedback. However, these approaches are either bounded by the policy planning capability of the frozen LLMs or hard to be transferred to new cases. In this work, we introduce a new dialogue policy planning paradigm to strategize LLMs for proactive dialogue problems with a tunable language model plug-in as a plug-and-play dialogue policy planner, named PPDPP. Specifically, we develop a novel training framework to facilitate supervised fine-tuning over available human-annotated data as well as reinforcement learning from goal-oriented AI feedback with dynamic interaction data collected by the LLM-based self-play simulation. In this manner, the LLM-powered dialogue agent can not only be generalized to different cases after the training, but also be applicable to different applications by just substituting the learned plug-in. In addition, we propose to evaluate the policy planning capability of dialogue systems under the interactive setting. Experimental results demonstrate that PPDPP consistently and substantially outperforms existing approaches on three different proactive dialogue applications, including negotiation, emotional support, and tutoring dialogues.

  • 5 authors
·
Oct 31, 2023

Proactive Agents for Multi-Turn Text-to-Image Generation Under Uncertainty

User prompts for generative AI models are often underspecified, leading to sub-optimal responses. This problem is particularly evident in text-to-image (T2I) generation, where users commonly struggle to articulate their precise intent. This disconnect between the user's vision and the model's interpretation often forces users to painstakingly and repeatedly refine their prompts. To address this, we propose a design for proactive T2I agents equipped with an interface to (1) actively ask clarification questions when uncertain, and (2) present their understanding of user intent as an understandable belief graph that a user can edit. We build simple prototypes for such agents and verify their effectiveness through both human studies and automated evaluation. We observed that at least 90% of human subjects found these agents and their belief graphs helpful for their T2I workflow. Moreover, we develop a scalable automated evaluation approach using two agents, one with a ground truth image and the other tries to ask as few questions as possible to align with the ground truth. On DesignBench, a benchmark we created for artists and designers, the COCO dataset (Lin et al., 2014), and ImageInWords (Garg et al., 2024), we observed that these T2I agents were able to ask informative questions and elicit crucial information to achieve successful alignment with at least 2 times higher VQAScore (Lin et al., 2024) than the standard single-turn T2I generation. Demo: https://github.com/google-deepmind/proactive_t2i_agents.

  • 7 authors
·
Dec 9, 2024

Exploring the Inquiry-Diagnosis Relationship with Advanced Patient Simulators

Online medical consultation (OMC) restricts doctors to gathering patient information solely through inquiries, making the already complex sequential decision-making process of diagnosis even more challenging. Recently, the rapid advancement of large language models has demonstrated a significant potential to transform OMC. However, most studies have primarily focused on improving diagnostic accuracy under conditions of relatively sufficient information, while paying limited attention to the "inquiry" phase of the consultation process. This lack of focus has left the relationship between "inquiry" and "diagnosis" insufficiently explored. In this paper, we first extract real patient interaction strategies from authentic doctor-patient conversations and use these strategies to guide the training of a patient simulator that closely mirrors real-world behavior. By inputting medical records into our patient simulator to simulate patient responses, we conduct extensive experiments to explore the relationship between "inquiry" and "diagnosis" in the consultation process. Experimental results demonstrate that inquiry and diagnosis adhere to the Liebig's law: poor inquiry quality limits the effectiveness of diagnosis, regardless of diagnostic capability, and vice versa. Furthermore, the experiments reveal significant differences in the inquiry performance of various models. To investigate this phenomenon, we categorize the inquiry process into four types: (1) chief complaint inquiry; (2) specification of known symptoms; (3) inquiry about accompanying symptoms; and (4) gathering family or medical history. We analyze the distribution of inquiries across the four types for different models to explore the reasons behind their significant performance differences. We plan to open-source the weights and related code of our patient simulator at https://github.com/LIO-H-ZEN/PatientSimulator.

  • 10 authors
·
Jan 16, 2025 4