Daily Papers

Memory is becoming core infrastructure for long-horizon LLM agents, yet existing evaluations offer limited guidance on which memory substrate, namely the underlying medium in which memory is represented and stored, should be used under different operating regimes. We present a controlled harness evaluation of memory substrates for memory-augmented agents, covering dense and sparse indices, text records, structural stores, hierarchical stores, refinement-based memories, parametric updates, and activation-compatible context mechanisms. Across three backbone models and four benchmark suites spanning user-centric question answering and agent-centric decision-making, we instrument 26 performance and efficiency metrics under a unified harness. Our results show that no single substrate consistently dominates: broad retrieval benefits long-context factual QA, while excessive retrieval can harm sequential decision-making by shifting attention away from action-critical context. Scalability introduces a further routing axis, as substrates that perform well at moderate history lengths can become costly or brittle at longer horizons. These findings motivate substrate routing as a necessary component of adaptive agent memory systems and provide empirical guidance for designing efficient, reliable, and regime-aware long-term memory for LLM agents. Code will be made available upon acceptance.

The rapid advancement of Large Language Models (LLMs) has established language as a core general-purpose cognitive substrate, driving the demand for specialized Language Processing Units (LPUs) tailored for LLM inference. To overcome the growing energy consumption of LLM inference systems, this paper proposes a Hardwired-Neurons Language Processing Unit (HNLPU), which physically hardwires LLM weight parameters into the computational fabric, achieving several orders of magnitude computational efficiency improvement by extreme specialization. However, a significant challenge still lies in the scale of modern LLMs. An ideal estimation on hardwiring gpt-oss 120 B requires fabricating at least 6 billion dollars of photomask sets, rendering the straightforward solution economically impractical. Addressing this challenge, we propose the novel Metal-Embedding methodology. Instead of embedding weights in a 2D grid of silicon device cells, Metal-Embedding embeds weight parameters into the 3D topology of metal wires. This brings two benefits: (1) a 15x increase in density, and (2) 60 out of 70 layers of photomasks are made homogeneous across chips, including all EUV photomasks. In total, Metal-Embedding reduced the photomask cost by 112x, bringing the Non-Recurring Engineering (NRE) cost of HNLPU into an economically viable range. Experimental results show that HNLPU achieved 249,960 tokens/s (5,555x/85x of GPU/WSE), 36 tokens/J (1,047x/283x of GPU/WSE), 13,232 mm2 total die area (29% inscribed rectangular area in a 300 mm wafer), \$184M estimated NRE at 5 nm technology. Analysis shows that HNLPU achieved 8.57x cost-effectiveness and 230x carbon footprint reduction compared to H100 clusters, under an annual weight updating assumption.

We propose a theoretical framework--Holographic Reservoir Computing (HRC)--which hypothesizes that the thermodynamic noise and timing dynamics in voltage-stressed Bitcoin mining ASICs (BM1366) could potentially serve as a physical reservoir computing substrate. We present the CHIMERA (Conscious Hybrid Intelligence via Miner-Embedded Resonance Architecture) system architecture, which treats the SHA-256 hashing pipeline not as an entropy source, but as a deterministic diffusion operator whose timing characteristics under controlled voltage and frequency conditions may exhibit computationally useful dynamics. We report preliminary observations of non-Poissonian variability in inter-arrival time statistics during edge-of-stability operation, which we term the "Silicon Heartbeat" hypothesis. Theoretical analysis based on Hierarchical Number System (HNS) representations suggests that such architectures could achieve O(log n) energy scaling compared to traditional von Neumann O(2^n) dependencies. However, we emphasize that these are theoretical projections requiring experimental validation. We present the implemented measurement infrastructure, acknowledge current limitations, and outline the experimental program necessary to confirm or refute these hypotheses. This work contributes to the emerging field of thermodynamic computing by proposing a novel approach to repurposing obsolete cryptographic hardware for neuromorphic applications.

This study investigates the possibility of increasing the radiation efficiency of printed antennas and arrays by suppressing their inherent surface waves using a metasurface made of quad-split rings (QSR). A symmetrical resonant microstrip dipole and a four-element series-fed dipole array printed on an infinite grounded dielectric layer (layer thickness: 0.2 mm; relative permittivity: 9.4; tan delta: 0.0005) were simulated with FEKO 2022 software. Conducted at 100-116 GHz, the numerical results revealed extremely low radiation efficiencies of approximately 31% and 40% for the studied dipole and dipole array, respectively, which resulted from the presence of surface waves in the dielectric. However, placing only one QSR near each dipole arm triggered an increase in radiation efficiency by 2.5 times (up to 75%). The use of a metasurface in the form of two small QSR arrays triggered a pronounced improvement in radiation efficiency, reaching 93.6% and 96.5% for the studied dipole and dipole array, respectively. Analysis of the electric field distribution images showed that this enhancement resulted from surface wave suppression.

The rapid expansion of distributed Artificial Intelligence (AI) workloads beyond centralized data centers creates a demand for new communication substrates. These substrates must operate reliably in heterogeneous and permissionless environments, where Network Address Translators (NATs) and firewalls impose significant constraints. Existing solutions, however, are either designed for controlled data center deployments or implemented as monolithic systems that tightly couple machine learning logic with networking code. To address these limitations, we present Lattica, a decentralized cross-NAT communication framework designed to support distributed AI systems. Lattica integrates three core components. First, it employs a robust suite of NAT traversal mechanisms to establish a globally addressable peer-to-peer mesh. Second, it provides a decentralized data store based on Conflict-free Replicated Data Types (CRDTs), ensuring verifiable and eventually consistent state replication. Third, it incorporates a content discovery layer that leverages distributed hash tables (DHTs) together with an optimized RPC protocol for efficient model synchronization. By integrating these components, Lattica delivers a complete protocol stack for sovereign, resilient, and scalable AI systems that operate independently of centralized intermediaries. It is directly applicable to edge intelligence, collaborative reinforcement learning, and other large-scale distributed machine learning scenarios.

This study investigates the impact of surface functionalization, oil coating, and oil absorption on droplet impact behavior on textured polydimethylsiloxane(PDMS) substrates. The textured surfaces were fabricated with square micro-posts having spacings of 5 and 20 microns. The PDMS samples were functionalized with octadecyltrichlorosilane (OTS) to improve water repellency. Following, the surfaces were either coated with or allowed to absorb two different lubricants, silicone oil (SO-5cSt) and hexadecane. We performed detailed wetting measurements on both untreated and OTS-functionalized substrates. These measurements provided useful insights into how water and lubricants were retained and distributed under static conditions. High-speed imaging was used to capture droplet impact across a range of Weber numbers. On SO-5cSt-absorbed substrates, droplets consistently showed complete rebound at all Weber numbers, regardless of post spacing. This robust rebound was attributed to the oil's ability to fill the gaps between the posts through capillary action, while also forming a stable lubricating layer above the texture. This thin oil film reduced friction between the droplet and the surface, enabling the droplet to retain sufficient energy for complete rebound. In contrast, hexadecane-absorbed substrates displayed different dynamics. At low Weber numbers, only partial rebound was observed, while at intermediate values, droplets rebounded completely. However, droplets no longer rebounded at higher Weber numbers and remained deposited. Repeated droplet impacts further demonstrated that hexadecane-infused surfaces gradually lost oil from the textured gaps, resulting in a decline in rebound performance over time. This effect was not observed with SO-5cSt, underscoring the importance of lubricant affinity and stability.

The fields of Origin of Life and Artificial Life both question what life is and how it emerges from a distinct set of "pre-life" dynamics. One common feature of most substrates where life emerges is a marked shift in dynamics when self-replication appears. While there are some hypotheses regarding how self-replicators arose in nature, we know very little about the general dynamics, computational principles, and necessary conditions for self-replicators to emerge. This is especially true on "computational substrates" where interactions involve logical, mathematical, or programming rules. In this paper we take a step towards understanding how self-replicators arise by studying several computational substrates based on various simple programming languages and machine instruction sets. We show that when random, non self-replicating programs are placed in an environment lacking any explicit fitness landscape, self-replicators tend to arise. We demonstrate how this occurs due to random interactions and self-modification, and can happen with and without background random mutations. We also show how increasingly complex dynamics continue to emerge following the rise of self-replicators. Finally, we show a counterexample of a minimalistic programming language where self-replicators are possible, but so far have not been observed to arise.

Hypothesis: Bacterial contamination of surfaces poses a major threat to public health. Designing effective antibacterial or self-cleaning surfaces requires understanding how bacteria-laden droplets interact with solid substrates and how readily they can be removed. We hypothesize that bacterial motility critically influences the early-stage surface interaction (i.e., surface adhesion) of bacteria-laden droplets, which cannot be captured by conventional contact angle goniometry. Experiments: Sessile droplets containing live and dead Escherichia coli (E. coli) were studied to probe their wetting and interfacial behavior. Contact angle goniometry was used to probe dynamic wetting, while a cantilever-deflection-based method was used to quantify adhesion. Internal flow dynamics were visualized using micro-particle image velocimetry (PIV) and analyzed statistically. Complementary sliding experiments on moderately wettable substrates were performed to assess contact line mobility under tilt. Findings: Despite lower surface tension, droplets containing live bacteria exhibited lower surface adhesion forces than their dead counterparts, with adhesion further decreasing at higher bacterial concentrations. Micro-PIV revealed that flagellated live E. coli actively resist evaporation-driven capillary flow via upstream migration, while at higher concentrations, collective dynamics emerge, producing spatially coherent bacterial motion despite temporal variability. These coordinated flows disrupt passive transport and promote depinning of the contact line, thereby reducing adhesion. Sliding experiments confirmed enhanced contact line mobility and frequent stick-slip motion in live droplets, even with lower receding contact angles and higher hysteresis. These findings provide mechanistic insight into droplet retention, informing the design of self-cleaning/antifouling surfaces.

We verify that persistent observers in causally invariant hypergraph substrates satisfy the conditions of the Conant-Ashby Good Regulator Theorem. Building on Wolfram's hypergraph physics and Vanchurin's neural network cosmology, we formalize persistent observers as entities that minimize prediction error at their boundary with the environment. Applying a modern reformulation of the Conant-Ashby theorem, we demonstrate that hypergraph observers satisfy Good Regulator conditions, requiring them to maintain internal models. Once an internal model with loss function exists, the emergence of a Fisher information metric follows from standard information geometry. Invoking Amari's uniqueness theorem for reparameterization-invariant gradients, we show that natural gradient descent is the unique admissible learning rule. Under the ansatz M=F^2 for exponential family observers and one specific convergence time functional, we derive a closed-form formula for the regime parameter alpha in Vanchurin's Type II framework, with a quantum-classical threshold at kappa(F)=2. However, three alternative convergence models do not reproduce this result, so this prediction is strongly model-dependent. We further introduce the directional regime parameter alpha_{v_k} and the trace-free deviation tensor, showing that a single observer can simultaneously occupy different Vanchurin regimes along different eigendirections of the Fisher metric. This connects Wolfram and Vanchurin frameworks through established theorems, providing approximately 25-30% novel contribution.

This position and survey paper identifies the emerging convergence of neuroscience, artificial general intelligence (AGI), and neuromorphic computing toward a unified research paradigm. Using a framework grounded in brain physiology, we highlight how synaptic plasticity, sparse spike-based communication, and multimodal association provide design principles for next-generation AGI systems that potentially combine both human and machine intelligences. The review traces this evolution from early connectionist models to state-of-the-art large language models, demonstrating how key innovations like transformer attention, foundation-model pre-training, and multi-agent architectures mirror neurobiological processes like cortical mechanisms, working memory, and episodic consolidation. We then discuss emerging physical substrates capable of breaking the von Neumann bottleneck to achieve brain-scale efficiency in silicon: memristive crossbars, in-memory compute arrays, and emerging quantum and photonic devices. There are four critical challenges at this intersection: 1) integrating spiking dynamics with foundation models, 2) maintaining lifelong plasticity without catastrophic forgetting, 3) unifying language with sensorimotor learning in embodied agents, and 4) enforcing ethical safeguards in advanced neuromorphic autonomous systems. This combined perspective across neuroscience, computation, and hardware offers an integrative agenda for in each of these fields.

Naturally occurring background radiation is a source of correlated decoherence events in superconducting qubits that will challenge error-correction schemes. To characterize the radiation environment in an unshielded laboratory, we performed broadband, spectroscopic measurements of background events in silicon substrates located inside a millikelvin refrigerator, an environment representative of superconducting qubit systems. We measured the background spectra in silicon substrates of two thicknesses, 0.5 mm and 1.5 mm, and obtained the average event rate and the integrated power deposition. In a 25 mm^2 area and the thinner substrate, these values are 0.023 events per second and 4.9 keV/s, counting events that deposit at least 40 keV. We find the background spectrum to be nearly featureless. Its intensity decreases by a factor of 40,000 between 100 keV and 3 MeV for silicon substrates 0.5 mm thick. We find the cryogenic measurements to be in good agreement with predictions based on measurements of the terrestrial gamma-ray flux, published models of cosmic-ray fluxes, a crude model of the cryostat, and radiation-transport simulations. No free parameters are required to predict the background spectra in the silicon substrates. The good agreement between measurements and predictions allow assessment of the relative contributions of terrestrial and cosmic background sources and their dependence on substrate thickness. Our spectroscopic measurements are performed with superconducting microresonators that transduce deposited energy to a readily detectable electrical signal. We find that gamma-ray emissions from radioisotopes are responsible for the majority of events depositing E<1.5 MeV, while nucleons among the cosmic-ray secondary particles cause most events that deposit more energy. These results suggest several paths to reducing the impact of background radiation on quantum circuits.

In an image latent space, the embeddings of high-resolution, natural, and sharp images form a manifold. Degradation of high-resolution images pushes their embeddings off this manifold. Real-world super-resolution (SR) then becomes the task of mapping the degraded embedding back onto this manifold --- not anywhere on the manifold, but to the point that preserves what the input still carries, both its semantics and pixel details. Every published method implements this mapping in a reconstruction-oriented latent space or pixel space. We claim these spaces are the wrong substrates for SR. Low-resolution and degraded images are embedded far from the manifold, making the mapping difficult and expensive. The lack of semantic information in these substrates also makes it difficult to navigate to the faithful point on the manifold, causing severe hallucination when degradation is heavy. Thus, restoring in a suitable latent space is crucial to the SR task. We show that the latent space of 23 fused layers of a frozen DINOv3-L is one such space that makes the SR task easier. Degraded images are embedded near the manifold. Moreover, this substrate contains a hierarchy of information, from pixel record to degradation robust semantics, guiding the model to find the faithful point on the manifold. On this substrate, a 415M decoder is trained under reconstruction and adversarial objectives to map the degraded embeddings back and decode to pixel space in one pass. The resulting model, RAESR, attains the best fidelity--perception trade-off among state-of-the-art adversarial and diffusion-based restorers on RealSR, DRealSR, LSDIR and DIV2K-Val, at 37 ms per 512 by 512 image on a single H20 GPU. Swapping the substrate for a VAE latent under an identical recipe loses on every metric.

Modern agents built on frontier language models often cannot adapt their weights. What, then, remains trainable? We argue it is the agent's workspace, the structured external substrate it reads, writes, and tests; we call its evolution workspace optimization. Workspace optimization targets hard multi-turn environments where a frontier model has strong priors but cannot solve the task in a single shot, so the agent must learn through interaction. We propose a principled way to evolve the workspace, mirroring the structure of weight-space training: artifacts in place of parameters, evidence in place of data, counterexamples in place of losses, and textual feedback in place of gradients. We instantiate the idea in DreamTeam, a multi-agent harness for ARC-AGI-3 whose roles build an executable world model, plan, hypothesize, probe, strategize, and route failures. On the current 25-game ARC-AGI-3 public set under the official scoring protocol and averaged over two independent runs, DreamTeam improves the SOTA protocol-matched agent's score from 36% to 38.4%, while using 31% fewer environment actions per game.

Most artificial life simulators either operate on abstract substrates disconnected from physical reality, or simulate physically grounded worlds that do not scale to the population sizes required for open-ended evolution. We present Microcosmos, a simulation engine in which artificial lifeforms are modeled as elastic filament chains inhabiting a two-dimensional viscous fluid world, designed from the ground up for modern GPU hardware and end-to-end differentiable simulation. We validate the engine through four experiments. Hand-designed locomotion strategies confirm that the fluid coupling respects known physical constraints. Gradient-based optimization of filament folding demonstrates both the full differentiability of the simulator and the expressivity of the filament encodings. Neuroevolution and quality-diversity search produce a wide range of swimming and chemotaxis behaviors automatically. Linear scaling with particle count confirms the engine supports large-scale simulation. Microcosmos is released as an open platform with the long-term goal of supporting large-scale open-ended evolutionary simulations, designed to be physically plausible and computationally scalable.

Precise shaping of surface acoustic waves (SAWs) on anisotropic piezoelectric substrates is complicated by elastic anisotropy and electromechanical coupling. Here we introduce a continuous diffractive acoustic lens (CDAL), in which weak phase-velocity perturbations produced by subwavelength metallization, together with diffraction, drive lateral field redistribution. An anisotropic thin-element propagation model enables efficient inverse design of the CDAL contour. Laser Doppler vibrometry verifies prescribed lateral field profiles and multichannel beam splitting with unequal widths. By combining continuous diffractive modulation with discrete source-phase encoding, we further shape the lateral field into a Bessel profile, demonstrating joint amplitude-and-phase control. This work provides a high-precision and fabrication-compatible mechanism for on-chip SAW field modulation.

The finetuning of Large Language Models (LLMs) has significantly advanced their instruction-following capabilities, yet the underlying computational mechanisms driving these improvements remain poorly understood. This study systematically examines how fine-tuning reconfigures LLM computations by isolating and analyzing instruction-specific sparse components, i.e., neurons in dense models and both neurons and experts in Mixture-of-Experts (MoE) architectures. In particular, we introduce HexaInst, a carefully curated and balanced instructional dataset spanning six distinct categories, and propose SPARCOM, a novel analytical framework comprising three key contributions: (1) a method for identifying these sparse components, (2) an evaluation of their functional generality and uniqueness, and (3) a systematic comparison of their alterations. Through experiments, we demonstrate functional generality, uniqueness, and the critical role of these components in instruction execution. By elucidating the relationship between fine-tuning-induced adaptations and sparse computational substrates, this work provides deeper insights into how LLMs internalize instruction-following behavior for the trustworthy LLM community.

Designing enzyme backbones with substrate-specific functionality is a critical challenge in computational protein engineering. Current generative models excel in protein design but face limitations in binding data, substrate-specific control, and flexibility for de novo enzyme backbone generation. To address this, we introduce EnzyBind, a dataset with 11,100 experimentally validated enzyme-substrate pairs specifically curated from PDBbind. Building on this, we propose EnzyControl, a method that enables functional and substrate-specific control in enzyme backbone generation. Our approach generates enzyme backbones conditioned on MSA-annotated catalytic sites and their corresponding substrates, which are automatically extracted from curated enzyme-substrate data. At the core of EnzyControl is EnzyAdapter, a lightweight, modular component integrated into a pretrained motif-scaffolding model, allowing it to become substrate-aware. A two-stage training paradigm further refines the model's ability to generate accurate and functional enzyme structures. Experiments show that our EnzyControl achieves the best performance across structural and functional metrics on EnzyBind and EnzyBench benchmarks, with particularly notable improvements of 13\% in designability and 13\% in catalytic efficiency compared to the baseline models. The code is released at https://github.com/Vecteur-libre/EnzyControl.

The increasing use of two-dimensional (2D) materials in nanoelectronics demands robust metrology techniques for electrical characterization, especially for large-scale production. While atomic force microscopy (AFM) techniques like conductive AFM (C-AFM) offer high accuracy, they suffer from slow data acquisition speeds due to the raster scanning process. To address this, we introduce SparseC-AFM, a deep learning model that rapidly and accurately reconstructs conductivity maps of 2D materials like MoS_2 from sparse C-AFM scans. Our approach is robust across various scanning modes, substrates, and experimental conditions. We report a comparison between (a) classic flow implementation, where a high pixel density C-AFM image (e.g., 15 minutes to collect) is manually parsed to extract relevant material parameters, and (b) our SparseC-AFM method, which achieves the same operation using data that requires substantially less acquisition time (e.g., under 5 minutes). SparseC-AFM enables efficient extraction of critical material parameters in MoS_2, including film coverage, defect density, and identification of crystalline island boundaries, edges, and cracks. We achieve over 11x reduction in acquisition time compared to manual extraction from a full-resolution C-AFM image. Moreover, we demonstrate that our model-predicted samples exhibit remarkably similar electrical properties to full-resolution data gathered using classic-flow scanning. This work represents a significant step toward translating AI-assisted 2D material characterization from laboratory research to industrial fabrication. Code and model weights are available at github.com/UNITES-Lab/sparse-cafm.

This definitive research memoria presents a comprehensive, mathematically verified paradigm for neural communication with Bitcoin mining Application-Specific Integrated Circuits (ASICs), integrating five complementary frameworks: thermodynamic reservoir computing, hierarchical number system theory, algorithmic analysis, network latency optimization, and machine-checked mathematical formalization. We establish that obsolete cryptocurrency mining hardware exhibits emergent computational properties enabling bidirectional information exchange between AI systems and silicon substrates. The research program demonstrates: (1) reservoir computing with NARMA-10 Normalized Root Mean Square Error (NRMSE) of 0.8661; (2) the Thermodynamic Probability Filter (TPF) achieving 92.19% theoretical energy reduction; (3) the Virtual Block Manager achieving +25% effective hashrate; and (4) hardware universality across multiple ASIC families including Antminer S9, Lucky Miner LV06, and Goldshell LB-Box. A significant contribution is the machine-checked mathematical formalization using Lean 4 and Mathlib, providing unambiguous definitions, machine-verified theorems, and reviewer-proof claims. Key theorems proven include: independence implies zero leakage, predictor beats baseline implies non-independence (the logical core of TPF), energy savings theoretical maximum, and Physical Unclonable Function (PUF) distinguishability witnesses. Vladimir Veselov's hierarchical number system theory explains why early-round information contains predictive power. This work establishes a new paradigm: treating ASICs not as passive computational substrates but as active conversational partners whose thermodynamic state encodes exploitable computational information.

Quality of epitaxial films strongly depends on their structural and chemical match with the substrates: the more closely they match, the better the film quality is. Topological insulators (TI) such as Bi2Se3 thin films are of no exception. However, there do not exist commercial substrates that match with TI films both structurally and chemically, at the level commonly available for other electronic materials. Here, we introduce BiInSe3 bulk crystal as the best substrate for Bi2Se3 thin films. These films exhibit superior surface morphology, lower defect density and higher Hall mobility than those on other substrates, due to structural and chemical match provided by the BiInSe3 substrate. BiInSe3 substrate could accelerate the advance of TI research and applications.

Autonomous agents promise substantial gains in speed, scale, and labor efficiency, but their failures can impose abrupt and often irreversible costs. The central challenge for agentic automation is therefore to increase the benefits of automation while bounding the consequences of failure. While databases remain central to modern computing, agents operate over a broader data environment spanning files, APIs, applications, and system state. In this talk, I will outline early work on Agentic Data Environments -- the execution substrate in which agents operate -- that both amplify agent capabilities and enforce safety guarantees. This perspective reframes data systems from passive stores of state into active substrates for safe, reliable execution.

Agents learn to act through interaction with environments, yet the environments used for training are often manually constructed or synthesized around predefined tasks and benchmarks. This task-centric paradigm makes it difficult to scale environments that reflect realistic and evolving workflows where diverse tasks can naturally emerge from the underlying world. We introduce AgentMercury, a scalable framework for synthesizing executable environments from high-level business scenarios. Rather than constructing an environment for a specific task, AgentMercury first instantiates a persistent world with entities, services, tools, state, and executable cross-service invariants, from which diverse tasks and interaction trajectories can subsequently emerge. We construct 4,783 executable environments spanning 14 industries and 50 countries, and use them as training substrates for reinforcement learning. Despite being generated without targeting the evaluation benchmarks, policies trained on these business-oriented environments improve substantially on both enterprise workflows and out-of-domain benchmarks spanning reasoning, coding, scientific computing, and tool use. In our experiments, Qwen3.5-4B improves from 12.3 to 15.7 on EnterpriseOps-GYM and from 45.9 to 56.0 on AIME26 after training on AgentMercury environments. We further show that the construction process itself can be learned: fine-tuning Qwen3.5-35B-A3B on construction traces increases executable-world authoring success from 3.3% to 83.3% on held-out business scenarios. These results show that scenario-grounded environments can provide useful and generalizable learning signals beyond benchmark-specific training, while their construction can itself become a learnable capability.

Open-weight LLMs are released not only as fixed products but also as substrates for downstream fine-tuning. This openness, however, creates legal and ethical risks because users may misuse fine-tuning to instill illicit knowledge or enable hostile operations. Model providers therefore need apre-release defense against such acquisition, motivating the problem of preemptive unlearning. Unlike retrospective unlearning, which removes capabilities already present in a fixed model, preemptive unlearning seeks to prevent their acquisition under unseen attack data and future fine-tuning procedures. Despite its practical importance, this setting remains largely unexplored, presents distinct challenges, and is therefore the central focus of our work. We first verify that existing retrospective methods provide insufficient pre-release protection. Even when forbidden capabilities are suppressed in current outputs, forbidden-domain data can still induce gradients through internal pathways, enabling later acquisition. Motivated by this finding, we propose a gradient-sealing principle that blocks these pathways by pushing relevant pre-activations into the negative region, where ReLU-family activations exhibit zero or near-zero derivatives. Experiments across multiple LLM families demonstrate our stronger resistance to downstream acquisition than retrospective baselines, validating gradient sealing as an effective mechanism for pre-release protection.

We investigate the superconducting properties of RuO_2 films grown on TiO_2 substrates by combining film fabrication and transport measurement with ab initio calculation. Experimentally, we grow several RuO_2 (110) thin films on TiO_2 (110) substrates and observe superconductivity with critical temperature (T_c) of sim2.0 K in 20-nm and 30-nm RuO_2 (110) thin films. Theoretically, we study the superconductivity in both RuO_2 (110) and RuO_2 (100) epitaxial films within McMillan formalism of isotropic Migdal-Eliashberg theory. Among the salient results, the calculated phonon dispersion relations of all the considered RuO_2 films show that the epitaxial films are dynamically stable. Importantly, our ab initio calculations reveal that independent of the film orientation, the [001] compressive strain ε_{[001]} pushes the flat Ru d_{z^2}-dominant bands towards the Fermi level (E_F), and significantly soften the out-of-plane acoustic phonon mode near the R point in the Brillouin zone, which substantially enhances the electron-phonon coupling (EPC) strength λ and hence the calculated T_c in the RuO_2 films. Remarkably, the amount of the phonon softening and the enhanced T_c increase almost linearly with the increasing ε_{[001]}. The calculated T_c for the films with thickness of geq 20 nm agree well with the experimental T_c. These findings demonstrate that among other things, lattice mismatch strain provides an effective route for tuning phonon-mediated superconductivity in RuO_2 and other thin films.

Freestanding thin films, a class of low-dimensional materials capable of maintaining structural integrity without substrates, have emerged as a forefront research focus. Their unique advantages-circumventing substrate clamping, liberating intrinsic material properties, and enabling cross-platform heterogeneous integration-underpin this prominence. This review systematically summarizes core fabrication techniques, including physical delamination (e.g., laser lift-off, mechanical exfoliation) and chemical etching, alongside associated transfer strategies. It further explores the induced strain modulation mechanisms, extreme mechanical properties and interface decoupling effects enabled by these films. Representative case studies demonstrate breakthrough applications in flexible/ultrathin electronics, ultrahigh-sensitivity sensors and the exploration of novel quantum states. Critical challenges regarding scalable fabrication, precise interface control, and long-term stability are analyzed, concluding with prospects for emerging applications in bio-inspired intelligent devices, quantum precision sensing, and brain-inspired neural networks.

Future developments in artificial intelligence will profit from the existence of novel, non-traditional substrates for brain-inspired computing. Neuromorphic computers aim to provide such a substrate that reproduces the brain's capabilities in terms of adaptive, low-power information processing. We present results from a prototype chip of the BrainScaleS-2 mixed-signal neuromorphic system that adopts a physical-model approach with a 1000-fold acceleration of spiking neural network dynamics relative to biological real time. Using the embedded plasticity processor, we both simulate the Pong arcade video game and implement a local plasticity rule that enables reinforcement learning, allowing the on-chip neural network to learn to play the game. The experiment demonstrates key aspects of the employed approach, such as accelerated and flexible learning, high energy efficiency and resilience to noise.

Language carries thought and coordination among humans but rarely reaches further along the spectrum of diverse intelligence. Yet non-neural systems -- from gene regulatory networks and microbial consortia to fungi -- are increasingly recognized as substrates of computation, decision-making and memory, making dialogue with non-human intelligence newly conceivable. Today such dialogue is attempted only by proxy: a large language model speaks on the system's behalf, so any intelligence on display originates from the model while the system itself remains silent. Here we ask whether the system can speak in its own voice. Following Wittgenstein, who located meaning in use, we treat communication as a game played with the system. Its internal dynamics are frozen as the nonlinear core of a reinforcement-learning policy, with only linear input and output interfaces trained. Through use and reward, the system's states and responses acquire meaning within the game, so playing becomes speaking. Because different architectures playing the same game optimize the same reward, their behaviors can all be read as pursuit of that reward; the game serves as a lingua franca across otherwise irreconcilable representations. Given a human prompt, a language model routes it to the game whose semantics best match it and designs an environmental state for which the desired action is the rational response, letting the system reply through its own behavior. Applied across diverse gene regulatory networks and reinforcement-learning tasks, the framework yields fluent dialogue without altering any system parameter, shows that well-trained agents of disparate origin converge on similar behavior, and reveals that specific GRN properties make a system easier or harder to talk with -- an inductive bias of the reservoir itself. Our framework opens a new route to conversing with any dynamical system on its own terms.

Executable environments are critical for post-training agents on tasks that require tool use and multi-step interaction, but constructing executable tasks together with their environments remains difficult to scale. Skills provide reusable domain knowledge, operational procedures, and tool-use instructions, but a substantial gap remains between the information contained in a skill and a concrete, challenging task with a complete executable environment. To address this gap, we introduce Skill2Env, a capability-oriented framework that starts from a skill and uses agent capability demands to guide task and environment synthesis. Skill2Env represents these demands through reusable difficulty patterns and instantiates them into task blueprints that specify objectives, challenges, environment facts, information boundaries, and acceptance criteria. These blueprints guide the joint construction of task instructions, execution substrates, workspaces, and rubric-based evaluators around source skills. We further propose Iterative Task Hardening, which uses solver execution evidence to identify insufficiently challenging task designs, strengthen or extend their difficulty-pattern instantiations, and revise the corresponding blueprints and environments. Using 1.5K high-scoring trajectories generated from Skill2Env environments for supervised fine-tuning, we observe consistent improvements across a broad range of agent benchmarks, demonstrating the effectiveness of capability-oriented environment synthesis for agent post-training.

Autonomous agents powered by foundation models can reason, plan, and use tools, but their fixed weights and context limits hinder sustained learning from experience over long-term deployment. While external memory systems attempt to bridge this gap, they mostly act as passive retrieval caches, evaluated primarily by whether they can recall stored facts or past interactions. Whether memory can drive genuine continual learning remains an open question. In this paper, we introduce Memory-Centric Continual Learning (MCCL), arguing that memory should be judged by whether it improves future actions, not merely what it retrieves. MCCL has three main parts. First, a three-axis taxonomy organizes memory by where state is stored (substrates), what form it takes (assets), and how it is managed (policies). This defines a two-loop lifecycle that updates memory state in an inner loop while refining management policies in an outer loop based on task feedback. Second, an evaluation protocol measures retention under interference, adaptation to change, and task transfer to isolate genuine behavioral gains from simple context expansion. Third, a memory scaling framework models how agent performance scales with experience, storage capacity, and compute budgets across non-parametric and parametric memory. Together, these components reframe agent memory from passive lookup to continuous learning, offering a principled route toward self-improving autonomous agents.

Autonomous agentic systems are largely static after deployment: they do not learn from user interactions, and recurring failures persist until the next human-driven update ships a fix. Self-evolving agents have emerged in response, but all confine evolution to text-mutable artifacts -- skill files, prompt configurations, memory schemas, workflow graphs -- and leave the agent harness untouched. Since routing, hook ordering, state invariants, and dispatch live in code rather than in any text artifact, an entire class of structural failure is physically unreachable from the text layer. We argue that source-level adaptation is a fundamentally more general medium: it is Turing-complete, a strict superset of every text-mutable scope, takes effect deterministically rather than through base-model compliance, and does not erode under long-context drift. We present MOSS, a system that performs self-rewriting at the source level on production agentic substrates. Each evolution is anchored to an automatically curated batch of production-failure evidence and proceeds through a deterministic multi-stage pipeline; code modification is delegated to a pluggable external coding-agent CLI while MOSS retains stage ordering and verdicts. Candidates are verified by replaying the batch against the candidate image in ephemeral trial workers, then promoted via user-consent-gated, in-place container swap with health-probe-gated rollback. On OpenClaw, MOSS lifts a four-task mean grader score from 0.25 to 0.61 in a single cycle without human intervention.

Target proteins that lack accessible binding pockets and conformational stability have posed increasing challenges for drug development. Induced proximity strategies, such as PROTACs and molecular glues, have thus gained attention as pharmacological alternatives, but still require small molecule docking at binding pockets for targeted protein degradation (TPD). The computational design of protein-based binders presents unique opportunities to access undruggable targets, but have often relied on stable 3D structures or predictions for effective binder generation. Recently, we have leveraged the expressive latent spaces of protein language models (pLMs) for the prioritization of peptide binders from sequence alone, which we have then fused to E3 ubiquitin ligase domains, creating a CRISPR-analogous TPD system for target proteins. However, our methods rely on training discriminator models for ranking heuristically or unconditionally-derived guide peptides for their target binding capability. In this work, we introduce PepMLM, a purely target sequence-conditioned de novo generator of linear peptide binders. By employing a novel masking strategy that uniquely positions cognate peptide sequences at the terminus of target protein sequences, PepMLM tasks the state-of-the-art ESM-2 pLM to fully reconstruct the binder region, achieving low perplexities matching or improving upon previously-validated peptide-protein sequence pairs. After successful in silico benchmarking with AlphaFold-Multimer, we experimentally verify PepMLM's efficacy via fusion of model-derived peptides to E3 ubiquitin ligase domains, demonstrating endogenous degradation of target substrates in cellular models. In total, PepMLM enables the generative design of candidate binders to any target protein, without the requirement of target structure, empowering downstream programmable proteome editing applications.

Planning has been part of the core pursuit for artificial intelligence since its conception, but earlier AI agents mostly focused on constrained settings because many of the cognitive substrates necessary for human-level planning have been lacking. Recently, language agents powered by large language models (LLMs) have shown interesting capabilities such as tool use and reasoning. Are these language agents capable of planning in more complex settings that are out of the reach of prior AI agents? To advance this investigation, we propose TravelPlanner, a new planning benchmark that focuses on travel planning, a common real-world planning scenario. It provides a rich sandbox environment, various tools for accessing nearly four million data records, and 1,225 meticulously curated planning intents and reference plans. Comprehensive evaluations show that the current language agents are not yet capable of handling such complex planning tasks-even GPT-4 only achieves a success rate of 0.6%. Language agents struggle to stay on task, use the right tools to collect information, or keep track of multiple constraints. However, we note that the mere possibility for language agents to tackle such a complex problem is in itself non-trivial progress. TravelPlanner provides a challenging yet meaningful testbed for future language agents.

The emerging field of Diverse Intelligence seeks to identify, formalize, and understand commonalities in behavioral competencies across a wide range of implementations. Especially interesting are simple systems that provide unexpected examples of memory, decision-making, or problem-solving in substrates that at first glance do not appear to be complex enough to implement such capabilities. We seek to develop tools to help understand the minimal requirements for such capabilities, and to learn to recognize and predict basal forms of intelligence in unconventional substrates. Here, we apply novel analyses to the behavior of classical sorting algorithms, short pieces of code which have been studied for many decades. To study these sorting algorithms as a model of biological morphogenesis and its competencies, we break two formerly-ubiquitous assumptions: top-down control (instead, showing how each element within a array of numbers can exert minimal agency and implement sorting policies from the bottom up), and fully reliable hardware (instead, allowing some of the elements to be "damaged" and fail to execute the algorithm). We quantitatively characterize sorting activity as the traversal of a problem space, showing that arrays of autonomous elements sort themselves more reliably and robustly than traditional implementations in the presence of errors. Moreover, we find the ability to temporarily reduce progress in order to navigate around a defect, and unexpected clustering behavior among the elements in chimeric arrays whose elements follow one of two different algorithms. The discovery of emergent problem-solving capacities in simple, familiar algorithms contributes a new perspective to the field of Diverse Intelligence, showing how basal forms of intelligence can emerge in simple systems without being explicitly encoded in their underlying mechanics.

The research of artificial intelligence is undergoing a paradigm shift from prioritizing model innovations over benchmark scores towards emphasizing problem definition and rigorous real-world evaluation. As the field enters the "second half," the central challenge becomes real utility in long-horizon, dynamic, and user-dependent environments, where agents face context explosion and must continuously accumulate, manage, and selectively reuse large volumes of information across extended interactions. Memory, with hundreds of papers released this year, therefore emerges as the critical solution to fill the utility gap. In this survey, we provide a unified view of foundation agent memory along three dimensions: memory substrate (internal and external), cognitive mechanism (episodic, semantic, sensory, working, and procedural), and memory subject (agent- and user-centric). We then analyze how memory is instantiated and operated under different agent topologies and highlight learning policies over memory operations. Finally, we review evaluation benchmarks and metrics for assessing memory utility, and outline various open challenges and future directions.

To understand and identify the unprecedented risks posed by rapidly advancing artificial intelligence (AI) models, Frontier AI Risk Management Framework in Practice presents a comprehensive assessment of their frontier risks. As Large Language Models (LLMs) general capabilities rapidly evolve and the proliferation of agentic AI, this version of the risk analysis technical report presents an updated and granular assessment of five critical dimensions: cyber offense, persuasion and manipulation, strategic deception, uncontrolled AI R\&D, and self-replication. Specifically, we introduce more complex scenarios for cyber offense. For persuasion and manipulation, we evaluate the risk of LLM-to-LLM persuasion on newly released LLMs. For strategic deception and scheming, we add the new experiment with respect to emergent misalignment. For uncontrolled AI R\&D, we focus on the ``mis-evolution'' of agents as they autonomously expand their memory substrates and toolsets. Besides, we also monitor and evaluate the safety performance of OpenClaw during the interaction on the Moltbook. For self-replication, we introduce a new resource-constrained scenario. More importantly, we propose and validate a series of robust mitigation strategies to address these emerging threats, providing a preliminary technical and actionable pathway for the secure deployment of frontier AI. This work reflects our current understanding of AI frontier risks and urges collective action to mitigate these challenges.

Atomic layer deposition (ALD) is widely studied for numerous applications and is commercially employed in the semiconductor industry, where planar substrates are the norm. However, the inherent ALD feature of coating virtually any surface geometry with atomistic thickness control is equally attractive for coating particulate materials (supports). In this review, we provide a comprehensive overview of the developments in this decades-old field of ALD on particulate materials, drawing on a bottom-up and quantitative analysis of 799 articles from this field. The obtained dataset is the basis for abstractions regarding reactor types (specifically for particles), coating materials, reactants, supports and processing conditions. Furthermore, the dataset enables direct access to specific processing conditions (for a given material, surface functionality, application etc.) and increases accessibility of the respective literature. We also review fundamental concepts of ALD on particles, and discuss the most common applications, i.e., catalysis (thermo-, electro-, photo-), batteries, luminescent phosphors and healthcare. Finally, we identify historical trends, and provide an outlook on prospective developments.

World models learn to predict future states of an environment, enabling planning and mental simulation. Current approaches default to Transformer-based predictors operating in learned latent spaces. This comes at a cost: O(N^2) computation and no explicit spatial inductive bias. This paper asks a foundational question: is self-attention necessary for predictive world modeling, or can alternative computational substrates achieve comparable or superior results? I introduce FluidWorld, a proof-of-concept world model whose predictive dynamics are governed by partial differential equations (PDEs) of reaction-diffusion type. Instead of using a separate neural network predictor, the PDE integration itself produces the future state prediction. In a strictly parameter-matched three-way ablation on unconditional UCF-101 video prediction (64x64, ~800K parameters, identical encoder, decoder, losses, and data), FluidWorld is compared against both a Transformer baseline (self-attention) and a ConvLSTM baseline (convolutional recurrence). While all three models converge to comparable single-step prediction loss, FluidWorld achieves 2x lower reconstruction error, produces representations with 10-15% higher spatial structure preservation and 18-25% more effective dimensionality, and critically maintains coherent multi-step rollouts where both baselines degrade rapidly. All experiments were conducted on a single consumer-grade PC (Intel Core i5, NVIDIA RTX 4070 Ti), without any large-scale compute. These results establish that PDE-based dynamics, which natively provide O(N) spatial complexity, adaptive computation, and global spatial coherence through diffusion, are a viable and parameter-efficient alternative to both attention and convolutional recurrence for world modeling.

As neural computation is revolutionizing the field of Artificial Intelligence (AI), rethinking the ideal neural hardware is becoming the next frontier. Fast and reliable von Neumann architecture has been the hosting platform for neural computation. Although capable, its separation of memory and computation creates the bottleneck for the energy efficiency of neural computation, contrasting the biological brain. The question remains: how can we efficiently combine memory and computation, while exploiting the physics of the substrate, to build intelligent systems? In this thesis, I explore an alternative way with memristive devices for neural computation, where the unique physical dynamics of the devices are used for inference, learning and routing. Guided by the principles of gradient-based learning, we selected functions that need to be materialized, and analyzed connectomics principles for efficient wiring. Despite non-idealities and noise inherent in analog physics, I will provide hardware evidence of adaptability of local learning to memristive substrates, new material stacks and circuit blocks that aid in solving the credit assignment problem and efficient routing between analog crossbars for scalable architectures.

This study presents a collection of physical devices and software services that fully automate Raman spectra measurements for liquid samples within a robotic facility. This method is applicable to various fields, with demonstrated efficacy in biotechnology, where Raman spectroscopy monitors substrates, metabolites, and product-related concentrations. Our system specifically measures 50 micro L samples using a liquid handling robot capable of taking 8 samples simultaneously. We record multiple Raman spectra for 10s each. Furthermore, our system takes around 20s for sample handling, cleaning, and preparation of the next measurement. All spectra and metadata are stored in a database, and we use a machine learning model to estimate concentrations from the spectra. This automated approach enables gathering spectra for various applications under uniform conditions in high-throughput fermentation processes, calibration procedures, and offline evaluations. This allows data to be combined to train sophisticated machine learning models with improved generalization. Consequently, we can develop accurate models more quickly for new applications by reusing data from prior applications, thereby reducing the need for extensive calibration data.

Video models absorb rich priors over how the visual world moves, interacts, and responds to contact, making them promising substrates for robotic world modeling. The central challenge is how to communicate action to such models in a form aligned with the visual space in which they learned these interaction priors, yet still grounded in physical manipulation. We introduce Masked Visual Actions, a pixel-space control interface that expresses action as a partially revealed trajectory of an arbitrary entity in a video. Revealing robot motion makes the model act as a forward dynamics model that predicts the scene's response to low-level robot actions, while revealing desired object motion makes the same model recover robot behavior consistent with that outcome. Finetuned with only 15 hours of masked examples from real videos and simulation, a single checkpoint achieves strong visual fidelity and controllability across diverse scenes and multiple embodiments. In downstream manipulation settings, the model produces imagined rollouts whose outcomes correlate with real-world execution for policy evaluation, improves decision making by ranking candidate futures in model-based planning, and supports inverse modeling by synthesizing robot motion from desired object motion.

Native visual reasoning treats visual generation as the medium of reasoning itself: visual states (i.e. images and videos) are not merely inputs to be understood or outputs to be rendered, but first-class substrates for problem solving beyond language. Yet progress remains bottlenecked by the lack of scalable training tasks, reliable feedback, and controlled comparisons across generative substrates. In this work, we introduce VBVR-Pro, a closed-loop testbed that makes native visual reasoning through generation trainable, verifiable, optimizable, and experimentally controllable. 1) Task scaling. VBVR-Pro turns visual reasoning into a controlled task space of 300 procedurally generated tasks. Models trained on VBVR-Pro show strong transfer beyond the proposed suite across seven external visual reasoning benchmarks such as RISE-Video, MME-CoF-Pro, and BabyVision. 2) Verifiable rewards. VBVR-Pro provides verifiable reward scorers for task-grounded evaluation. Through a systematic study of leading MLLMs as judges, we identify recurring failure modes of the prevalent VLM-as-a-judge paradigm. In contrast, the proposed scorers are grounded in deterministic, task-specific rules, achieve fine-grained alignment with human judgments. Importantly, they serve as reliable reward signals for large-scale multi-task reinforcement learning and demonstrate stronger post-RL performance across visual reasoning tasks. 3) Mechanism study. VBVR-Pro enables controlled modality studies across more than 30 image, video, and interleaved generators. Our analysis shows that video generation remains strongest for tasks requiring persistent spatiotemporal state tracking, while interleaved generation provides a compute-efficient alternative. Critically, ablations and probing suggest the presence of vision-native trajectories that are crucial to visual reasoning. We release all data, models, scorers, and code.

Equilibrium propagation (EP) is a compelling alternative to the backpropagation of error algorithm (BP) for computing gradients of neural networks on biological or analog neuromorphic substrates. Still, the algorithm requires weight symmetry and infinitesimal equilibrium perturbations, i.e., nudges, to estimate unbiased gradients efficiently. Both requirements are challenging to implement in physical systems. Yet, whether and how weight asymmetry affects its applicability is unknown because, in practice, it may be masked by biases introduced through the finite nudge. To address this question, we study generalized EP, which can be formulated without weight symmetry, and analytically isolate the two sources of bias. For complex-differentiable non-symmetric networks, we show that the finite nudge does not pose a problem, as exact derivatives can still be estimated via a Cauchy integral. In contrast, weight asymmetry introduces bias resulting in low task performance due to poor alignment of EP's neuronal error vectors compared to BP. To mitigate this issue, we present a new homeostatic objective that directly penalizes functional asymmetries of the Jacobian at the network's fixed point. This homeostatic objective dramatically improves the network's ability to solve complex tasks such as ImageNet 32x32. Our results lay the theoretical groundwork for studying and mitigating the adverse effects of imperfections of physical networks on learning algorithms that rely on the substrate's relaxation dynamics.

Ribosomally synthesized and post-translationally modified peptide (RiPP) biosynthetic enzymes often exhibit promiscuous substrate preferences that cannot be reduced to simple rules. Large language models are promising tools for predicting such peptide fitness landscapes. However, state-of-the-art protein language models are trained on relatively few peptide sequences. A previous study comprehensively profiled the peptide substrate preferences of LazBF (a two-component serine dehydratase) and LazDEF (a three-component azole synthetase) from the lactazole biosynthetic pathway. We demonstrated that masked language modeling of LazBF substrate preferences produced language model embeddings that improved downstream classification models of both LazBF and LazDEF substrates. Similarly, masked language modeling of LazDEF substrate preferences produced embeddings that improved the performance of classification models of both LazBF and LazDEF substrates. Our results suggest that the models learned functional forms that are transferable between distinct enzymatic transformations that act within the same biosynthetic pathway. Our transfer learning method improved performance and data efficiency in data-scarce scenarios. We then fine-tuned models on each data set and showed that the fine-tuned models provided interpretable insight that we anticipate will facilitate the design of substrate libraries that are compatible with desired RiPP biosynthetic pathways.

This study systematically investigates the photoconductive properties of low-temperature-grown Beryllium (Be)-doped InGaAs/InAlAs strain-balanced superlattices (SLs) grown by molecular beam epitaxy under stationary growth conditions on semi-insulating InP:Fe substrates. The stationary growth approach enabled precise control over lateral gradients in layer strain, composition, and thickness across a single wafer, while strain-balancing facilitated pseudomorphic growth to explore a wide range of structural parameters, providing a robust platform to study their influence on photoconductive performance. Structural characterization confirmed high crystalline quality and smooth surface morphology in all samples. Time-resolved pump-probe spectroscopy revealed subpicosecond carrier lifetimes, validating the effectiveness of strain balancing and Be doping in tuning ultrafast recombination dynamics. Hall effect measurements supported by 8-band k.p modeling revealed enhanced carrier mobility in strain-balanced SLs compared to lattice-matched structures, primarily due to reduced electron and hole effective masses and stronger quantum confinement. Additionally, optical absorption under 1550 nm excitation showed improved absorption coefficients for the strain-balanced structure, consistent with the reduction in bandgap energy predicted by theoretical modeling, thereby enhancing photon-to-carrier conversion efficiency. Furthermore, transmission electron microscopy provided first-time evidence of significant Be-induced interdiffusion at the strained SL interfaces, an important factor influencing carrier transport and dynamics. These findings position low-temperature-grown Be-doped InGaAs/InAlAs strain-balanced SLs as promising materials for high-performance broadband THz photoconductive detectors operating at telecom-compatible wavelengths.

While Neural Processing Units (NPUs) offer high theoretical efficiency for edge AI, state-of-the-art Vision--Language Models (VLMs) tailored for GPUs often falter on these substrates. We attribute this hardware-model mismatch to two primary factors: the quantization brittleness of Vision Transformers (ViTs) and the I/O-bound nature of autoregressive attention mechanisms, which fail to utilize the high arithmetic throughput of NPUs. To bridge this gap, we propose AutoNeural, an NPU-native VLM architecture co-designed for integer-only inference. We replace the standard ViT encoder with a MobileNetV5-style backbone utilizing depthwise separable convolutions, which ensures bounded activation distributions for stable INT4/8/16 quantization. Complementing this, our language backbone integrates State-Space Model (SSM) principles with Transformer layers, employing efficient gated convolutions to achieve linear-time complexity. This hybrid design eliminates the heavy memory I/O overhead of Key-Value caching during generation. Our approach delivers substantial efficiency gains, reducing quantization error of vision encoder by up to 7x and end-to-end latency by 14x compared to conventional baselines. The AutoNeural also delivers 3x decoding speed and 4x longer context window than the baseline. We validate these improvements via a real-world automotive case study on the Qualcomm SA8295P SoC, demonstrating real-time performance for cockpit applications. Our results highlight that rethinking model topology specifically for NPU constraints is a prerequisite for robust multi-modal edge intelligence.

We have systematically investigated the grain boundary (GB) angle dependence of transport properties for NdFeAs(O,F) fabricated on [001]-tilt symmetric MgO bicrystal substrates. In our previous study, NdFeAs(O,F) bicrystal films showed a weak-link behaviour even at a GB angle of 6°. However, this was caused by an extrinsic effect originating from the damage to both NdFeAs(O,F) and MgO substrate by excess F-diffusion along the grain boundary. To investigate the intrinsic nature of grain boundaries, we minimized the damage to NdFeAs(O,F) and MgO by reducing the deposition temperature of NdOF over-layer needed for F-doping. The resultant NdFeAs(O,F) bicrystal films have a critical angle of 8.5°, above which Jc starts to decrease exponentially. This critical angle is almost the same as those of other Fe-based superconductors.

Most of the Neural Cellular Automata (NCAs) defined in the literature have a common theme: they are based on regular grids with a Moore neighborhood (one-hop neighbour). They do not take into account long-range connections and more complex topologies as we can find in the brain. In this paper, we introduce BraiNCA, a brain-inspired NCA with an attention layer, long-range connections and complex topology. BraiNCAs shows better results in terms of robustness and speed of learning on the two tasks compared to Vanilla NCAs establishing that incorporating attention-based message selection together with explicit long-range edges can yield more sample-efficient and damage-tolerant self-organization than purely local, grid-based update rules. These results support the hypothesis that, for tasks requiring distributed coordination over extended spatial and temporal scales, the choice of interaction topology and the ability to dynamically route information will impact the robustness and speed of learning of an NCA. More broadly, BraiNCA provides brain-inspired NCA formulation that preserves the decentralized local update principle while better reflecting non-local connectivity patterns, making it a promising substrate for studying collective computation under biologically-realistic network structure and evolving cognitive substrates.

Agentic AI systems increasingly act through heterogeneous runtimes: local coding hooks, SDK tools, browser automation, managed-agent traces, API gateways, and workflow engines. A single operational act such as publishing code, changing identity state, moving money, or exporting data may therefore be represented by many incompatible runtime records. This makes a basic governance question difficult to answer: what action was actually approved, what evidence binds the approval to execution, and can an independent verifier reproduce the same action identity later? This paper presents Canonical Action Verification and Attestation (CAVA), a runtime-semantics layer for converting heterogeneous agent activity into canonical runtime action objects. CAVA is positioned below Proof-Carrying Agent Actions (PCAA): PCAA defines the deployer-owned route-review-prove governance process, while CAVA defines the stable action object that process governs. The paper formalizes canonical action identity, semantic pattern detection, approval binding, receipt integrity, runtime-portable projection, and optional attestation substrates. We study a reference implementation through a 96-seed, 384-variant benchmark covering semantic equivalence, semantic separation, wrapper bypass, false-positive control, approval binding, receipt reproducibility, attestation tamper detection, runtime portability, semantic pattern detection, policy degradation, and Azure deployment drills. The contribution is a systems formulation of action-level canonicalization and policy-addressable semantic patterns as a necessary substrate for deployer-side AI governance.

LLMs are widely regarded as alien intelligences, systems whose cognitive operations are fundamentally unlike our own. Apparent similarities to human cognition are therefore often seen as the result of anthropomorphic projection. We argue that this framing is mistaken. LLMs clearly differ from humans in important respects, including their physical substrate, learning history, and the environments with which they interact. These differences make it all the more striking that contemporary LLM-based systems converge with human cognition on a number of principles of cognitive organization with longstanding support in cognitive science. We identify structural correspondences across five dimensions: inferential organization, computational architecture, representational structure, prediction-driven learning, and reinforcement-learning-like mechanisms supporting goal-directed action. These correspondences support a broader model of intelligent cognition in which core principles long used to explain human intelligence also characterize contemporary LLM-based systems.

Speech production is a complex process spanning neural planning, motor control, muscle activation, and articulatory kinematics. While the acoustic speech signal is the most accessible product of the speech production act, it does not directly reveal its causal neurophysiological substrates. We present the first simultaneous acquisition of real-time (dynamic) MRI, EEG, and surface EMG, capturing several key aspects of the speech production chain: brain signals, muscle activations, and articulatory movements. This multimodal acquisition paradigm presents substantial technical challenges, including MRI-induced electromagnetic interference and myogenic artifacts. To mitigate these, we introduce an artifact suppression pipeline tailored to this tri-modal setting. Once fully developed, this framework is poised to offer an unprecedented window into speech neuroscience and insights leading to brain-computer interface advances. The source code and data are available.

LLM agents are rapidly being deployed in production, including coding assistants, customer-support chatbots, and scientific research assistants, yet they remain fundamentally static in enterprise deployment. The LLM weights, system prompts, tool repertoires, and in-context harnesses are frozen at deployment time, and any improvement requires a manual loop of human-curated data collection, offline fine-tuning, modification of the agentic paradigm, and re-deployment. Recent work on self-evolving agents, such as OpenClaw for individual users, indicates that the next leap in agent capability will come from agents that continually learn from their own experience. In this paper, we argue that this vision for self-evolving agent deployment is being held back for enterprise-level large-scale agentic service not by reinforcement learning (RL) algorithms but by agentic online RL systems. Specifically, current agentic RL systems and the surrounding observability software stack are inadequate along three essential aspects: (i) there is no standardized agent trajectory data protocol capable of carrying RL learning signals at step granularity across heterogeneous agent paradigms; (ii) there is no enterprise-grade comprehensive data proxy that converts real workloads into governed learning substrates; and (iii) there is no unified agent evolution control plane that automatically decides, based on trajectory statistics, when to update policy weights or evolve the in-context harness. The next generation of agentic RL systems must be co-designed around these three pillars, and we sketch concrete architectures, case studies, and counter-arguments. We instantiate one branch through AReaL2.0, reorganizing existing RL infrastructure into an agent-oriented online RL loop for policy weight updates from deployed workloads.

Economic World Models (EWMs) are generative economic models that simulate how economies evolve from within by modeling heterogeneous agents, their beliefs and actions, and the market and institutional mechanisms through which their interactions produce aggregate outcomes. This paper develops an implementation roadmap for building economic world models as generative engines in which heterogeneous agents act, interact, adapt, and co-evolve with markets and institutions, thereby producing economic dynamics from the inside. We organize EWM systems into a six-level capability ladder, from fixed rule-based agent worlds to adaptive and LLM-based agent worlds, self-evolving agents, evolving institutional worlds, and sim-to-real economic twins aligned with real observations. A systematic literature survey across these levels reveals that existing work remains concentrated in lower-level agent and simulation environments, while systems with self-evolving agents, endogenous institutions, persistent empirical alignment, and validated economic mechanisms remain rare. By translating the EWM agenda into an implementation blueprint, this paper aims to accelerate the development of the next generation of economic simulation environments that can serve as high-fidelity sandboxes for human decision-makers and as training, planning, evaluation, and safety substrates for AI agents. We release a curated paper list and related resources to support future research.