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SubscribeComputer vision for liquid samples in hospitals and medical labs using hierarchical image segmentation and relations prediction
This work explores the use of computer vision for image segmentation and classification of medical fluid samples in transparent containers (for example, tubes, syringes, infusion bags). Handling fluids such as infusion fluids, blood, and urine samples is a significant part of the work carried out in medical labs and hospitals. The ability to accurately identify and segment the liquids and the vessels that contain them from images can help in automating such processes. Modern computer vision typically involves training deep neural nets on large datasets of annotated images. This work presents a new dataset containing 1,300 annotated images of medical samples involving vessels containing liquids and solid material. The images are annotated with the type of liquid (e.g., blood, urine), the phase of the material (e.g., liquid, solid, foam, suspension), the type of vessel (e.g., syringe, tube, cup, infusion bottle/bag), and the properties of the vessel (transparent, opaque). In addition, vessel parts such as corks, labels, spikes, and valves are annotated. Relations and hierarchies between vessels and materials are also annotated, such as which vessel contains which material or which vessels are linked or contain each other. Three neural networks are trained on the dataset: One network learns to detect vessels, a second net detects the materials and parts inside each vessel, and a third net identifies relationships and connectivity between vessels.
DS6, Deformation-aware Semi-supervised Learning: Application to Small Vessel Segmentation with Noisy Training Data
Blood vessels of the brain provide the human brain with the required nutrients and oxygen. As a vulnerable part of the cerebral blood supply, pathology of small vessels can cause serious problems such as Cerebral Small Vessel Diseases (CSVD). It has also been shown that CSVD is related to neurodegeneration, such as Alzheimer's disease. With the advancement of 7 Tesla MRI systems, higher spatial image resolution can be achieved, enabling the depiction of very small vessels in the brain. Non-Deep Learning-based approaches for vessel segmentation, e.g., Frangi's vessel enhancement with subsequent thresholding, are capable of segmenting medium to large vessels but often fail to segment small vessels. The sensitivity of these methods to small vessels can be increased by extensive parameter tuning or by manual corrections, albeit making them time-consuming, laborious, and not feasible for larger datasets. This paper proposes a deep learning architecture to automatically segment small vessels in 7 Tesla 3D Time-of-Flight (ToF) Magnetic Resonance Angiography (MRA) data. The algorithm was trained and evaluated on a small imperfect semi-automatically segmented dataset of only 11 subjects; using six for training, two for validation, and three for testing. The deep learning model based on U-Net Multi-Scale Supervision was trained using the training subset and was made equivariant to elastic deformations in a self-supervised manner using deformation-aware learning to improve the generalisation performance. The proposed technique was evaluated quantitatively and qualitatively against the test set and achieved a Dice score of 80.44 pm 0.83. Furthermore, the result of the proposed method was compared against a selected manually segmented region (62.07 resultant Dice) and has shown a considerable improvement (18.98\%) with deformation-aware learning.
Solar System Elemental Abundances from the Solar Photosphere and CI-Chondrites
Solar photospheric abundances and CI-chondrite compositions are reviewed and updated to obtain representative solar system abundances of the elements and their isotopes. The new photospheric abundances obtained here lead to higher solar metallicity. Full 3D NLTE photospheric analyses are only available for 11 elements. A quality index for analyses is introduced. For several elements, uncertainties remain large. Protosolar mass fractions are H (X = 0.7060), He (Y = 0.2753), and for metals Li to U (Z = 0.0187). The protosolar (C+N)/H agrees within 13% with the ratio for the solar core from the Borexino experiment. Elemental abundances in CI-chondrites were screened by analytical methods, sample sizes, and evaluated using concentration frequency distributions. Aqueously mobile elements (e.g., alkalis, alkaline earths, etc.) often deviate from normal distributions indicating mobilization and/or sequestration into carbonates, phosphates, and sulfates. Revised CI-chondrite abundances of non-volatile elements are similar to earlier estimates. The moderately volatile elements F and Sb are higher than before, as are C, Br and I, whereas the CI-abundances of Hg and N are now significantly lower. The solar system nuclide distribution curves of s-process elements agree within 4% with s-process predictions of Galactic chemical evolution models. P-process nuclide distributions are assessed. No obvious correlation of CI-chondritic to solar elemental abundance ratios with condensation temperatures is observed, nor is there one for ratios of CI-chondrites/solar wind abundances.
xView3-SAR: Detecting Dark Fishing Activity Using Synthetic Aperture Radar Imagery
Unsustainable fishing practices worldwide pose a major threat to marine resources and ecosystems. Identifying vessels that do not show up in conventional monitoring systems -- known as ``dark vessels'' -- is key to managing and securing the health of marine environments. With the rise of satellite-based synthetic aperture radar (SAR) imaging and modern machine learning (ML), it is now possible to automate detection of dark vessels day or night, under all-weather conditions. SAR images, however, require a domain-specific treatment and are not widely accessible to the ML community. Maritime objects (vessels and offshore infrastructure) are relatively small and sparse, challenging traditional computer vision approaches. We present the largest labeled dataset for training ML models to detect and characterize vessels and ocean structures in SAR imagery. xView3-SAR consists of nearly 1,000 analysis-ready SAR images from the Sentinel-1 mission that are, on average, 29,400-by-24,400 pixels each. The images are annotated using a combination of automated and manual analysis. Co-located bathymetry and wind state rasters accompany every SAR image. We also provide an overview of the xView3 Computer Vision Challenge, an international competition using xView3-SAR for ship detection and characterization at large scale. We release the data (https://iuu.xview.us/{https://iuu.xview.us/}) and code (https://github.com/DIUx-xView{https://github.com/DIUx-xView}) to support ongoing development and evaluation of ML approaches for this important application.
vesselFM: A Foundation Model for Universal 3D Blood Vessel Segmentation
Segmenting 3D blood vessels is a critical yet challenging task in medical image analysis. This is due to significant imaging modality-specific variations in artifacts, vascular patterns and scales, signal-to-noise ratios, and background tissues. These variations, along with domain gaps arising from varying imaging protocols, limit the generalization of existing supervised learning-based methods, requiring tedious voxel-level annotations for each dataset separately. While foundation models promise to alleviate this limitation, they typically fail to generalize to the task of blood vessel segmentation, posing a unique, complex problem. In this work, we present vesselFM, a foundation model designed specifically for the broad task of 3D blood vessel segmentation. Unlike previous models, vesselFM can effortlessly generalize to unseen domains. To achieve zero-shot generalization, we train vesselFM on three heterogeneous data sources: a large, curated annotated dataset, data generated by a domain randomization scheme, and data sampled from a flow matching-based generative model. Extensive evaluations show that vesselFM outperforms state-of-the-art medical image segmentation foundation models across four (pre-)clinically relevant imaging modalities in zero-, one-, and few-shot scenarios, therefore providing a universal solution for 3D blood vessel segmentation.
Conditions for radiative zones in the molecular hydrogen envelope of Jupiter and Saturn: The role of alkali metals
Interior models of gas giants in the Solar System traditionally assume a fully convective molecular hydrogen envelope. However, recent observations from the Juno mission suggest a possible depletion of alkali metals in Jupiter's molecular hydrogen envelope, indicating that a stable radiative layer could exist at the kilobar level. Recent studies propose that deep stable layers help reconcile various Jupiter observations, including its atmospheric water and CO abundances and the depth of its zonal winds. However, opacity tables used to infer stable layers are often outdated and incomplete, leaving the precise molecular hydrogen envelope composition required for a deep radiative zone uncertain. In this paper, we determine atmospheric compositions that can lead to the formation of a radiative zone at the kilobar level in Jupiter and Saturn today. We computed radiative opacity tables covering pressures up to 10^5 bar, including the most abundant molecules present in the gas giants of the Solar System, as well as contributions from free electrons, metal hydrides, oxides, and atomic species, using the most up-to-date line lists published in the literature. These tables were used to calculate Rosseland-mean opacities for the molecular hydrogen envelopes of Jupiter and Saturn, which were then compared to the critical mean opacity required to maintain convection. We find that the presence of a radiative zone is controlled by the existence of K, Na, and NaH in the atmosphere of Jupiter and Saturn. For Jupiter, the elemental abundance of K and Na must be less than sim 10^{-3} times solar to form a radiative zone. In contrast, for Saturn, the required abundance for K and Na is below sim 10^{-4} times solar.
Image-level Regression for Uncertainty-aware Retinal Image Segmentation
Accurate retinal vessel (RV) segmentation is a crucial step in the quantitative assessment of retinal vasculature, which is needed for the early detection of retinal diseases and other conditions. Numerous studies have been conducted to tackle the problem of segmenting vessels automatically using a pixel-wise classification approach. The common practice of creating ground truth labels is to categorize pixels as foreground and background. This approach is, however, biased, and it ignores the uncertainty of a human annotator when it comes to annotating e.g. thin vessels. In this work, we propose a simple and effective method that casts the RV segmentation task as an image-level regression. For this purpose, we first introduce a novel Segmentation Annotation Uncertainty-Aware (SAUNA) transform, which adds pixel uncertainty to the ground truth using the pixel's closeness to the annotation boundary and vessel thickness. To train our model with soft labels, we generalize the earlier proposed Jaccard metric loss to arbitrary hypercubes for soft Jaccard index (Intersection-over-Union) optimization. Additionally, we employ a stable version of the Focal-L1 loss for pixel-wise regression. We conduct thorough experiments and compare our method to a diverse set of baselines across 5 retinal image datasets. Our empirical results indicate that the integration of the SAUNA transform and these segmentation losses led to significant performance boosts for different segmentation models. Particularly, our methodology enables UNet-like architectures to substantially outperform computational-intensive baselines. Our implementation is available at https://github.com/Oulu-IMEDS/SAUNA.
AB5 type multicomponent TiVCoNiMn2 high-entropy alloy
Recent theoretical and practical research has focused on multi-component High Entropy Alloys (HEAs), which have superior mechanical and functional properties than standard alloys based on a single major element, thereby establishing a new field. A multi-component HEA contains five or more primary elements at concentrations ranging from 5 to 35 atomic percent. We examined the microstructure and mechanical properties of TiVCoNiMn2 HEA. The mixing enthalpy and other thermodynamic parameters were determined using Meidma's model. TiVCoNiMn2 exhibits a mixing enthalpy of -15.6 kJ/mol and an atomic radius mismatch of approximately 10.03%. HEA is derived from both hydride and non-hydride-producing elements. This could be a useful hydrogen storage material. The hydrogen absorption/desorption capabilities of these HEAs are promising.
Multiphysics Continuous Shape Optimization of the TAP Reactor Components
The Transatomic Power (TAP) reactor has an unusual design for a molten salt reactor technology, building upon the foundation laid by the Molten Salt Reactor Experiment (MSRE). This design introduces three key modifications to enhance efficiency and compactness: a revised fuel salt composition, an alternative moderator material, and moderator pins surrounded by the molten salt fuel. Unlike traditional solid-fueled reactors that rely on excess positive reactivity at the beginning of life, the TAP concept employs a dynamic approach. The core's design, featuring a cylindrical geometry with square assemblies of moderator rods surrounded by flowing fuel salt, provides flexibility in adjusting the moderator-to-fuel ratio during operation - using movable moderator rods - further adding criticality control capability in addition to the control rods system. Shape optimization of the core can play a crucial role in enhancing performance and efficiency. By applying multiphysics continuous shape optimization techniques to key components, such as the unit cells of the TAP reactor or its moderator assemblies, we can fine-tune the reactor's geometry to achieve optimal performance in key physics like neutronics and thermal hydraulics. We explore this aspect using the optimization module in the Multiphysics Object Oriented Simulation Environment (MOOSE) framework which allows for multiphysics continuous shape optimization. The results reported here illustrate the benefits of applying continuous shape optimization in the design of nuclear reactor components and can help in extending the TAP reactor's performance.
Coronal Abundance Fractionation Linked to Chromospheric Transverse MHD Waves in a Solar Active Region Observed with FISS/GST and EIS/Hinode
Elemental abundances in the solar corona differ from those in the photosphere, with low first ionization potential (FIP) elements being enhanced, a phenomenon known as the FIP effect. This enhancement is attributed to ponderomotive forces linked to magnetohydrodynamic (MHD) waves, particularly incompressible transverse waves. Our study investigates the relationship between coronal abundance fractionation and chromospheric transverse MHD waves by examining the spatial correlation between FIP fractionation and these waves and by analyzing their properties to test the ponderomotive force model. We used H alpha data from the Fast Imaging Solar Spectrograph at the Goode Solar Telescope to detect chromospheric transverse MHD waves and Si{X} (low FIP) and S{X} (high FIP) spectra from Hinode EUV Imaging Spectrometer to determine relative abundances in an active region. Extrapolated linear force free magnetic fields from Solar Dynamics Observatory/Helioseismic and Magnetic Imager magnetograms further linked the observed chromospheric waves with coronal composition. Approximately 400 wave packets were identified and characterized by their period, velocity amplitude, propagation speed, and direction. These incompressible or weakly compressible waves were mainly observed near loop footpoints in the sunspot penumbra and superpenumbral fibrils. Regions of high FIP fractionation coincided with closed magnetic fields where these waves were present, and low-frequency, downward-propagating waves comprised about 43/% of the total. Our results demonstrate a strong correlation between coronal abundance fractionation and chromospheric transverse MHD waves, supporting the view that the FIP effect is driven by the ponderomotive force from these waves.
