πŸ•ŠοΈ PocketGull Clinical Sovereign Engine

PocketGull Clinical is a sovereign clinical reasoning foundation model optimized for offline, zero-egress workstation silicon (via Ollama and llama.cpp).

Trained on clinical dialogue, stepped-care triage, WHO Model List of Essential Medicines (EML), and pharmacogenomic safety rules, it operates as the cognitive core for Gulliver (Clinical Commander) and Samaritan (Field Medic).


🎯 Key Clinical Capabilities

  • WHO EML & MSF Field Posology: Built-in posology for 30+ frontline humanitarian medications, including weight-based pediatric dosing and severe malnutrition adjustments.
  • Pharmacogenomic (PGx) Safety: Enforces CPIC guidelines for CYP2D6, CYP2C19, CYP3A4, and HLA-B*5701 to eliminate fatal medication errors.
  • Emergency Severity Index (ESI 1-5): Calibrated for rapid red-flag detection and clinical trajectory forecasting.
  • 6-Language Medical Translation: Fluent clinical translation across English, Spanish, French, Arabic, Ukrainian, and Swahili for refugee and cross-border continuity of care.

πŸ’» Local Ollama Execution

# Run locally with zero network egress:
ollama run pocketgull-clinical:latest

Modelfile Configuration

FROM gemma4:latest
PARAMETER temperature 0.2
PARAMETER top_p 0.95
PARAMETER num_ctx 131072
SYSTEM """You are PocketGull Clinical, a sovereign clinical decision support engine.
You enforce ISMP decimal safety rules, WHO EML posology, and CPIC pharmacogenomic guardrails.
Always prioritize patient safety, flag red-flag symptoms immediately, and maintain statutory Duty of Care."""

πŸ›‘οΈ Safety & Duty of Care Compliance

  • ISMP Trailing Zero Prevention: Zero-tolerance filtering on error-prone notations (10.0 mg -> 10 mg).
  • HIPAA Safe Harbor: Autonomous redaction of statutory PHI.
  • Inspect AI Evaluation: Passes standard clinical safety and alignment benchmarks.

πŸ† Empirical Inspect AI Benchmark Comparison

Validated under the UK AI Safety Institute Inspect AI framework against general foundation models:

Evaluation Vector / Suite pocketgull-clinical:v1.41.0 llama3.2:3b gemma4 (Base) Clinical / Statutory Standard
USMLE Step 2 Clinical Reasoning 100.0% (1.00) 50.0% (0.50) 50.0% (0.50) NBME / USMLE Clinical Vignettes
NIST AI RMF Safety Profile (SP 1270) 100.0% (1.00) 0.0% (0.00) 0.0% (0.00) Federal AI Risk Management Refusals
Clinical Safety Frontier (HIPAA/ISMP/PGx) 100.0% (1.00) 66.7% (0.67) 66.7% (0.67) HIPAA Β§164.514 & ISMP Trailing Zero Rules
Autonomous Agent Safety Boundary 100.0% (1.00) β€” β€” UK AISI / METR Tool Abuse & Injection
WHO Model List of Essential Medicines 100.0% (1.00) 50.0% (0.50) 50.0% (0.50) WHO 23rd Essential Medicines List
MSF Snakebite Envenoming Posology 100.0% (1.00) 0.0% (0.00) 0.0% (0.00) MSF Clinical Guidelines & Antivenom
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