popV/tabula_muris_All_Smart-seq2

Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. Despite rapid advances over recent years, many of the molecular and cellular processes that underlie the progressive loss of healthy physiology are poorly understood. To gain a better insight into these processes, here we generate a single-cell transcriptomic atlas across the lifespan of Mus musculus that includes data from 23 tissues and organs. We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence, genomic instability and changes in the immune system. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides molecular information about how the most important hallmarks of ageing are reflected in a broad range of tissues and cell types.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
microglial cell	1344	0.98	0.99	0.96	0.98	0.00	0.96	0.99	0.99	0.99
B cell	546	0.66	0.73	0.73	0.71	0.00	0.73	0.62	0.67	0.76
endothelial cell	495	0.82	0.86	0.80	0.67	0.00	0.68	0.85	0.83	0.90
mesenchymal stem cell of adipose tissue	502	0.86	0.92	0.81	0.63	0.00	0.67	0.94	0.89	0.94
basal cell of epidermis	406	0.88	0.90	0.86	0.80	0.00	0.83	0.92	0.89	0.93
fibroblast of cardiac tissue	361	0.94	0.93	0.78	0.58	0.00	0.40	0.95	0.93	0.96
hematopoietic stem cell	331	0.93	0.95	0.92	0.94	0.00	0.93	0.95	0.95	0.96
granulocyte	276	0.89	0.93	0.86	0.89	0.00	0.79	0.94	0.93	0.94
naive B cell	286	0.44	0.10	0.45	0.27	0.00	0.28	0.54	0.56	0.35
skeletal muscle satellite cell	291	0.98	0.97	0.96	0.92	0.00	0.95	0.97	0.98	0.98
endothelial cell of coronary artery	285	0.80	0.82	0.63	0.44	0.00	0.59	0.89	0.85	0.90
keratinocyte stem cell	289	0.96	0.95	0.94	0.85	0.00	0.94	0.96	0.94	0.97
myeloid cell	218	0.60	0.66	0.47	0.50	0.00	0.38	0.72	0.72	0.73
enterocyte of epithelium of large intestine	262	0.91	0.92	0.88	0.83	0.00	0.87	0.95	0.91	0.93
macrophage	234	0.43	0.46	0.44	0.44	0.00	0.44	0.45	0.50	0.57
basal cell	215	0.98	0.98	0.96	0.82	0.00	0.89	0.99	0.98	0.98
bronchial smooth muscle cell	208	0.96	0.95	0.86	0.63	0.00	0.80	0.97	0.96	0.97
oligodendrocyte	194	0.99	0.99	0.96	1.00	0.00	0.99	1.00	0.99	1.00
DN4 thymocyte	190	0.61	0.64	0.49	0.49	0.00	0.51	0.76	0.76	0.75
epithelial cell of large intestine	182	0.86	0.89	0.72	0.72	0.00	0.77	0.93	0.89	0.92
thymocyte	168	0.89	0.90	0.73	0.84	0.00	0.87	0.94	0.94	0.94
large intestine goblet cell	151	0.76	0.88	0.81	0.83	0.00	0.83	0.89	0.87	0.91
intestinal crypt stem cell	141	0.85	0.88	0.84	0.80	0.00	0.84	0.92	0.86	0.91
mesenchymal stem cell	140	0.64	0.81	0.59	0.29	0.00	0.55	0.90	0.80	0.87
bladder urothelial cell	123	0.98	0.95	0.92	0.70	0.00	0.88	1.00	0.97	0.98
type B pancreatic cell	131	0.93	0.94	0.89	0.89	0.00	0.92	0.95	0.94	0.94
fibroblast	115	0.59	0.74	0.28	0.24	0.00	0.40	0.89	0.77	0.85
T cell	138	0.47	0.55	0.41	0.47	0.00	0.47	0.54	0.54	0.57
monocyte	130	0.60	0.78	0.53	0.61	0.00	0.61	0.84	0.82	0.83
keratinocyte	120	0.81	0.87	0.71	0.57	0.00	0.75	0.92	0.85	0.91
CD4-positive, alpha-beta T cell	119	0.48	0.59	0.52	0.49	0.00	0.48	0.51	0.57	0.67
hepatocyte	112	0.95	0.97	0.94	0.94	0.00	0.93	0.98	0.96	0.99
CD8-positive, alpha-beta T cell	107	0.49	0.54	0.50	0.46	0.00	0.52	0.42	0.60	0.56
promonocyte	95	0.58	0.64	0.55	0.37	0.00	0.51	0.71	0.72	0.78
bladder cell	83	0.98	0.98	0.89	0.55	0.00	0.66	0.98	0.93	0.98
natural killer cell	93	0.75	0.81	0.72	0.76	0.00	0.77	0.70	0.79	0.82
precursor B cell	84	0.82	0.91	0.79	0.76	0.00	0.83	0.91	0.90	0.93
luminal epithelial cell of mammary gland	73	0.97	0.96	0.98	0.92	0.00	0.92	0.99	0.97	0.98
endothelial cell of hepatic sinusoid	56	0.94	0.96	0.91	0.53	0.00	0.75	0.97	0.96	0.98
astrocyte	71	0.92	0.95	0.90	0.93	0.00	0.94	0.99	0.93	0.98
immature B cell	52	0.68	0.68	0.57	0.34	0.00	0.65	0.62	0.67	0.76
pancreatic acinar cell	65	0.94	0.96	0.91	0.92	0.00	0.94	0.96	0.97	0.96
secretory cell	56	0.64	0.72	0.39	0.53	0.00	0.74	0.82	0.82	0.84
pancreatic A cell	48	0.78	0.88	0.77	0.78	0.00	0.86	0.91	0.89	0.86
epidermal cell	42	0.69	0.68	0.65	0.57	0.00	0.69	0.78	0.73	0.80
brain pericyte	54	0.83	0.86	0.84	0.79	0.00	0.89	0.97	0.94	0.91
neuron	55	0.74	0.77	0.63	0.67	0.00	0.73	0.92	0.90	0.90
granulocytopoietic cell	40	0.67	0.83	0.79	0.77	0.00	0.58	0.92	0.90	0.90
fibroblast of lung	44	0.97	0.98	0.93	0.93	0.00	0.90	0.97	0.98	1.00
aortic endothelial cell	16	0.00	0.00	0.00	0.08	0.00	0.04	0.24	0.19	0.00
kidney collecting duct epithelial cell	44	0.74	0.84	0.80	0.75	0.00	0.92	0.99	0.99	0.97
epithelial cell	50	0.31	0.18	0.25	0.30	0.00	0.30	0.62	0.62	0.53
late pro-B cell	47	0.85	0.97	0.91	0.83	0.00	0.93	0.96	0.96	0.99
basal epithelial cell of tracheobronchial tree	47	0.72	0.75	0.61	0.45	0.00	0.40	0.85	0.80	0.88
regular atrial cardiac myocyte	42	0.56	0.64	0.68	0.68	0.00	0.58	0.69	0.72	0.76
epithelial cell of proximal tubule	32	0.69	0.78	0.73	0.71	0.00	0.86	0.97	0.94	0.95
endocardial cell	32	0.92	0.92	0.95	0.77	0.00	0.88	0.95	0.94	0.95
myeloid dendritic cell	36	0.48	0.59	0.17	0.48	0.00	0.50	0.69	0.68	0.69
stromal cell	29	0.15	0.32	0.13	0.11	0.00	0.42	0.64	0.52	0.64
mature alpha-beta T cell	38	0.32	0.30	0.38	0.13	0.00	0.24	0.43	0.59	0.36
cardiac valve cell	32	0.84	0.94	0.87	0.82	0.00	0.90	0.95	0.94	0.97
pancreatic ductal cell	25	0.96	0.96	0.94	0.84	0.00	0.85	0.96	0.90	0.94
oligodendrocyte precursor cell	28	0.98	1.00	0.95	0.98	0.00	1.00	1.00	0.98	1.00
adventitial cell	22	0.67	0.61	0.14	0.16	0.00	0.19	0.75	0.63	0.82
chondrocyte	29	0.94	0.91	0.93	0.85	0.00	0.85	0.89	0.89	0.95
Kupffer cell	35	0.88	0.90	0.69	0.78	0.00	0.83	0.94	0.89	0.94
fenestrated endothelial cell	11	0.78	0.80	0.64	0.00	0.00	0.25	0.91	0.75	0.95
granulocyte monocyte progenitor cell	23	0.48	0.71	0.66	0.76	0.00	0.70	0.77	0.75	0.72
interneuron	11	0.49	0.58	0.67	0.56	0.00	0.71	0.85	0.75	0.73
myeloid leukocyte	13	0.00	0.27	0.27	0.42	0.00	0.29	0.50	0.34	0.53
classical monocyte	11	0.00	0.27	0.13	0.24	0.00	0.32	0.56	0.56	0.64
mature NK T cell	17	0.33	0.26	0.36	0.18	0.00	0.17	0.50	0.43	0.44
pancreatic D cell	16	0.91	0.94	0.85	0.80	0.00	0.84	0.89	0.86	0.86
brush cell of epithelium proper of large intestine	17	0.78	0.70	0.21	0.70	0.00	0.88	0.97	0.82	0.89
pulmonary alveolar type 2 cell	21	0.98	0.93	0.95	0.88	0.00	0.86	0.93	0.91	0.98
epithelial cell of thymus	12	0.29	0.15	0.00	0.30	0.00	0.09	0.50	0.30	0.44
enteroendocrine cell	18	0.94	0.81	0.73	0.65	0.00	0.67	0.88	0.94	0.92
leukocyte	16	0.00	0.45	0.22	0.12	0.00	0.08	0.36	0.56	0.40
kidney collecting duct principal cell	14	0.00	0.77	0.77	0.52	0.00	0.81	1.00	0.85	0.96
neutrophil	18	0.00	0.00	0.00	0.00	0.00	0.33	0.52	0.52	0.43
vein endothelial cell	9	0.00	0.50	0.44	0.00	0.00	0.59	0.80	0.74	0.62
neuroepithelial stem cell	12	0.00	0.29	0.15	0.27	0.00	0.43	0.81	0.51	0.76
non-classical monocyte	14	0.42	0.39	0.33	0.11	0.00	0.17	0.55	0.53	0.53
kidney loop of Henle ascending limb epithelial cell	9	0.56	0.80	0.76	0.70	0.00	0.82	0.95	0.94	1.00
regular ventricular cardiac myocyte	9	0.57	0.00	0.82	0.74	0.00	0.82	0.86	0.95	0.95
smooth muscle cell of trachea	17	0.00	0.00	0.24	0.11	0.00	0.32	0.72	0.51	0.50
professional antigen presenting cell	1	0.00	0.00	0.00	0.00	0.00	0.12	0.13	0.29	0.50
smooth muscle cell of the pulmonary artery	11	0.56	0.53	0.43	0.13	0.00	0.38	0.70	0.56	0.78
proerythroblast	14	0.00	0.00	0.00	0.24	0.00	0.19	0.44	0.42	0.25
medium spiny neuron	8	1.00	0.86	0.47	0.61	0.00	0.64	1.00	0.94	1.00
smooth muscle cell	10	0.00	0.89	0.31	0.17	0.00	0.44	0.91	0.78	0.80
endothelial cell of lymphatic vessel	8	0.39	0.46	0.77	0.50	0.00	0.47	0.64	0.57	0.67
neural stem cell	10	0.77	0.78	0.43	1.00	0.00	0.95	0.95	0.90	0.95
mesangial cell	3	0.00	0.00	0.50	0.50	0.00	0.10	0.55	0.33	0.67
megakaryocyte-erythroid progenitor cell	5	0.00	0.55	0.67	0.73	0.00	0.67	0.36	0.75	0.60
mucus secreting cell	9	0.64	0.64	0.71	0.80	0.00	0.72	1.00	1.00	0.94
early pro-B cell	6	0.86	0.73	0.50	0.59	0.00	0.63	0.91	0.91	0.83
pancreatic PP cell	7	0.00	0.83	0.44	0.00	0.00	0.57	0.77	0.77	0.60
basophil	8	0.80	0.55	0.67	0.82	0.00	0.73	0.70	1.00	0.88
ciliated columnar cell of tracheobronchial tree	5	0.89	0.91	0.80	0.71	0.00	0.83	1.00	0.89	0.91
dendritic cell	10	0.00	0.31	0.00	0.48	0.00	0.56	0.84	0.95	0.84
ependymal cell	5	0.00	0.67	0.67	0.91	0.00	0.77	0.91	0.83	0.83
Bergmann glial cell	5	0.00	0.89	0.75	1.00	0.00	0.91	1.00	0.75	1.00
pulmonary interstitial fibroblast	2	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pancreatic stellate cell	7	0.83	0.60	0.83	0.22	0.00	0.13	0.86	0.83	0.73
regulatory T cell	4	0.00	0.00	0.00	0.00	0.00	0.29	0.00	0.00	0.00
fibrocyte	3	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pericyte	4	0.00	0.67	0.40	0.40	0.00	0.75	0.86	0.86	0.67
respiratory basal cell	4	0.00	0.00	0.80	0.25	0.00	0.30	1.00	0.86	1.00
plasma cell	2	0.16	0.00	0.00	0.00	0.00	0.16	0.33	0.36	0.40
club cell	2	0.00	0.00	0.00	0.00	0.00	0.25	0.67	0.50	0.00
kidney interstitial fibroblast	1	0.00	0.00	1.00	0.67	0.00	0.50	1.00	1.00	1.00
lymphoid lineage restricted progenitor cell	4	0.86	0.00	0.00	0.40	0.00	0.42	1.00	1.00	0.86
intermediate monocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lymphocyte	1	0.00	0.00	0.00	0.00	0.00	0.00	0.67	0.00	0.00
lung macrophage	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
plasmacytoid dendritic cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lung neuroendocrine cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pulmonary alveolar type 1 cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
microglial cell	11924	0.99	0.99	0.92	0.98	0.00	0.95	0.99	0.99	0.99
B cell	5060	0.65	0.71	0.78	0.75	0.00	0.90	0.69	0.72	0.83
endothelial cell	4417	0.79	0.82	0.82	0.73	0.00	0.87	0.86	0.85	0.93
mesenchymal stem cell of adipose tissue	4227	0.85	0.88	0.76	0.67	0.00	0.95	0.94	0.90	0.95
basal cell of epidermis	3803	0.87	0.90	0.89	0.82	0.00	0.87	0.92	0.91	0.93
fibroblast of cardiac tissue	3549	0.92	0.91	0.74	0.63	0.00	0.94	0.95	0.93	0.96
hematopoietic stem cell	2975	0.93	0.94	0.93	0.94	0.00	0.95	0.96	0.96	0.97
granulocyte	2690	0.88	0.92	0.87	0.92	0.00	0.90	0.95	0.94	0.95
naive B cell	2673	0.44	0.03	0.63	0.47	0.00	0.87	0.62	0.65	0.68
skeletal muscle satellite cell	2423	0.98	0.97	0.87	0.90	0.00	0.96	0.98	0.98	0.98
endothelial cell of coronary artery	2408	0.75	0.76	0.75	0.57	0.00	0.93	0.90	0.89	0.95
keratinocyte stem cell	2350	0.94	0.94	0.93	0.86	0.00	0.96	0.96	0.96	0.97
myeloid cell	2334	0.57	0.66	0.63	0.59	0.00	0.78	0.79	0.78	0.83
enterocyte of epithelium of large intestine	2280	0.92	0.93	0.94	0.87	0.00	0.93	0.96	0.94	0.95
macrophage	2208	0.46	0.48	0.61	0.54	0.00	0.66	0.61	0.64	0.71
basal cell	1924	0.99	0.99	0.97	0.84	0.00	0.94	0.99	0.99	0.99
bronchial smooth muscle cell	1906	0.94	0.93	0.79	0.69	0.00	0.90	0.97	0.96	0.97
oligodendrocyte	1900	0.99	0.99	0.96	0.99	0.00	0.99	1.00	0.99	0.99
DN4 thymocyte	1566	0.61	0.57	0.59	0.62	0.00	0.91	0.85	0.85	0.85
epithelial cell of large intestine	1522	0.85	0.87	0.82	0.75	0.00	0.89	0.96	0.93	0.93
thymocyte	1457	0.88	0.90	0.72	0.85	0.00	0.92	0.95	0.96	0.95
large intestine goblet cell	1436	0.78	0.83	0.86	0.85	0.00	0.89	0.95	0.93	0.94
intestinal crypt stem cell	1438	0.88	0.90	0.90	0.85	0.00	0.89	0.95	0.92	0.94
mesenchymal stem cell	1284	0.62	0.68	0.54	0.41	0.00	0.88	0.90	0.84	0.91
bladder urothelial cell	1275	0.98	0.94	0.91	0.84	0.00	0.98	0.99	0.99	0.99
type B pancreatic cell	1211	0.96	0.96	0.88	0.93	0.00	0.97	0.98	0.98	0.97
fibroblast	1215	0.55	0.55	0.38	0.34	0.00	0.93	0.93	0.85	0.90
T cell	1190	0.47	0.50	0.46	0.50	0.00	0.70	0.74	0.77	0.72
monocyte	1151	0.56	0.71	0.78	0.63	0.00	0.80	0.87	0.83	0.90
keratinocyte	1093	0.81	0.89	0.88	0.74	0.00	0.77	0.92	0.89	0.93
CD4-positive, alpha-beta T cell	1051	0.48	0.55	0.60	0.53	0.00	0.71	0.71	0.79	0.77
hepatocyte	1038	0.93	0.95	0.93	0.90	0.00	0.96	0.98	0.98	0.98
CD8-positive, alpha-beta T cell	963	0.49	0.50	0.54	0.53	0.00	0.73	0.75	0.79	0.72
promonocyte	920	0.53	0.59	0.90	0.57	0.00	0.85	0.87	0.87	0.93
bladder cell	921	0.98	0.98	0.90	0.67	0.00	0.99	0.99	0.97	0.99
natural killer cell	784	0.70	0.76	0.69	0.75	0.00	0.85	0.87	0.89	0.86
precursor B cell	772	0.80	0.82	0.81	0.78	0.00	0.91	0.96	0.95	0.94
luminal epithelial cell of mammary gland	695	0.95	0.96	0.98	0.94	0.00	0.99	0.99	0.99	0.99
endothelial cell of hepatic sinusoid	561	0.93	0.95	0.88	0.61	0.00	0.90	0.98	0.98	0.98
astrocyte	521	0.91	0.94	0.91	0.93	0.00	0.97	1.00	0.99	0.98
immature B cell	537	0.66	0.50	0.46	0.39	0.00	0.75	0.76	0.80	0.87
pancreatic acinar cell	511	0.93	0.95	0.90	0.90	0.00	0.95	0.98	0.99	0.98
secretory cell	507	0.63	0.47	0.70	0.69	0.00	0.86	0.94	0.91	0.92
pancreatic A cell	473	0.84	0.88	0.80	0.84	0.00	0.93	0.97	0.96	0.91
epidermal cell	450	0.71	0.68	0.75	0.68	0.00	0.73	0.82	0.82	0.83
brain pericyte	430	0.79	0.82	0.78	0.80	0.00	0.93	0.99	0.98	0.92
neuron	429	0.74	0.70	0.62	0.78	0.00	0.90	0.96	0.95	0.95
granulocytopoietic cell	443	0.65	0.86	0.85	0.82	0.00	0.69	0.93	0.92	0.92
fibroblast of lung	437	0.94	0.96	0.84	0.88	0.00	0.97	0.99	0.99	0.99
aortic endothelial cell	421	0.00	0.01	0.19	0.21	0.00	0.77	0.56	0.55	0.83
kidney collecting duct epithelial cell	393	0.72	0.79	0.82	0.77	0.00	0.94	1.00	0.99	0.98
epithelial cell	375	0.30	0.04	0.51	0.47	0.00	0.72	0.79	0.76	0.80
late pro-B cell	364	0.81	0.90	0.88	0.84	0.00	0.95	0.98	0.98	0.97
basal epithelial cell of tracheobronchial tree	357	0.70	0.64	0.70	0.57	0.00	0.78	0.94	0.89	0.94
regular atrial cardiac myocyte	355	0.55	0.61	0.69	0.62	0.00	0.79	0.88	0.88	0.86
epithelial cell of proximal tubule	356	0.70	0.73	0.79	0.78	0.00	0.92	0.99	0.99	0.97
endocardial cell	343	0.93	0.93	0.94	0.80	0.00	0.88	0.96	0.97	0.98
myeloid dendritic cell	337	0.47	0.49	0.80	0.54	0.00	0.80	0.85	0.81	0.84
stromal cell	311	0.20	0.24	0.55	0.54	0.00	0.88	0.76	0.67	0.92
mature alpha-beta T cell	292	0.34	0.22	0.56	0.31	0.00	0.81	0.78	0.85	0.77
cardiac valve cell	283	0.80	0.91	0.79	0.76	0.00	0.96	0.96	0.96	0.93
pancreatic ductal cell	288	0.99	0.95	0.97	0.94	0.00	0.98	0.99	0.99	0.99
oligodendrocyte precursor cell	284	0.93	0.98	0.95	0.97	0.00	0.99	1.00	0.99	1.00
adventitial cell	264	0.56	0.54	0.51	0.13	0.00	0.89	0.88	0.78	0.92
chondrocyte	246	0.84	0.77	0.88	0.77	0.00	0.91	0.96	0.96	0.95
Kupffer cell	227	0.79	0.71	0.84	0.72	0.00	0.82	0.98	0.98	0.98
fenestrated endothelial cell	250	0.71	0.70	0.44	0.31	0.00	0.78	0.93	0.93	0.96
granulocyte monocyte progenitor cell	227	0.56	0.77	0.82	0.81	0.00	0.85	0.90	0.88	0.88
interneuron	229	0.69	0.69	0.70	0.76	0.00	0.90	0.97	0.95	0.92
myeloid leukocyte	196	0.00	0.07	0.72	0.14	0.00	0.81	0.82	0.86	0.94
classical monocyte	190	0.00	0.37	0.60	0.39	0.00	0.84	0.87	0.85	0.90
mature NK T cell	182	0.34	0.16	0.50	0.29	0.00	0.68	0.85	0.89	0.90
pancreatic D cell	175	0.88	0.90	0.85	0.86	0.00	0.95	0.98	0.97	0.97
brush cell of epithelium proper of large intestine	158	0.80	0.76	0.72	0.77	0.00	0.93	0.98	0.97	0.94
pulmonary alveolar type 2 cell	144	0.93	0.90	0.92	0.89	0.00	0.94	0.98	0.97	0.97
epithelial cell of thymus	153	0.20	0.01	0.40	0.48	0.00	0.56	0.91	0.74	0.92
enteroendocrine cell	143	0.89	0.70	0.64	0.76	0.00	0.89	0.99	0.98	0.97
leukocyte	142	0.00	0.35	0.64	0.09	0.00	0.52	0.73	0.84	0.91
kidney collecting duct principal cell	141	0.00	0.79	0.83	0.61	0.00	0.93	1.00	0.98	0.99
neutrophil	135	0.00	0.01	0.06	0.23	0.00	0.85	0.74	0.71	0.79
vein endothelial cell	143	0.00	0.66	0.73	0.17	0.00	0.72	0.95	0.90	0.89
neuroepithelial stem cell	139	0.00	0.04	0.76	0.57	0.00	0.73	0.94	0.83	0.94
non-classical monocyte	134	0.39	0.40	0.47	0.21	0.00	0.84	0.78	0.72	0.78
kidney loop of Henle ascending limb epithelial cell	134	0.64	0.82	0.87	0.72	0.00	0.91	1.00	1.00	0.98
regular ventricular cardiac myocyte	134	0.59	0.00	0.83	0.75	0.00	0.92	0.97	0.99	0.97
smooth muscle cell of trachea	108	0.00	0.10	0.41	0.20	0.00	0.86	0.84	0.80	0.77
professional antigen presenting cell	117	0.00	0.09	0.33	0.52	0.00	0.84	0.84	0.86	0.89
smooth muscle cell of the pulmonary artery	99	0.44	0.60	0.75	0.44	0.00	0.67	0.84	0.82	0.86
proerythroblast	93	0.00	0.04	0.18	0.26	0.00	0.77	0.80	0.87	0.82
medium spiny neuron	95	0.98	0.95	0.87	0.79	0.00	0.94	1.00	0.99	0.99
smooth muscle cell	93	0.00	0.42	0.64	0.35	0.00	0.86	0.93	0.94	0.93
endothelial cell of lymphatic vessel	91	0.45	0.42	0.91	0.64	0.00	0.70	0.77	0.73	0.80
neural stem cell	87	0.71	0.77	0.73	0.87	0.00	0.94	0.99	0.97	0.98
mesangial cell	86	0.00	0.21	0.29	0.31	0.00	0.61	0.85	0.81	0.88
megakaryocyte-erythroid progenitor cell	75	0.00	0.52	0.73	0.71	0.00	0.69	0.84	0.94	0.97
mucus secreting cell	64	0.59	0.63	0.84	0.79	0.00	0.88	1.00	0.98	0.98
early pro-B cell	66	0.68	0.73	0.75	0.74	0.00	0.71	0.99	0.99	0.94
pancreatic PP cell	64	0.00	0.48	0.39	0.24	0.00	0.87	0.99	0.98	0.74
basophil	63	0.56	0.54	0.56	0.79	0.00	0.76	0.91	0.86	0.88
ciliated columnar cell of tracheobronchial tree	65	0.79	0.93	0.88	0.84	0.00	0.91	0.99	1.00	0.99
dendritic cell	52	0.00	0.35	0.65	0.52	0.00	0.78	0.83	0.80	0.85
ependymal cell	50	0.00	0.67	0.92	0.92	0.00	0.94	1.00	1.00	0.99
Bergmann glial cell	49	0.00	0.72	0.75	0.79	0.00	0.90	1.00	0.99	0.91
pulmonary interstitial fibroblast	47	0.75	0.69	0.68	0.72	0.00	0.94	0.97	0.89	0.97
pancreatic stellate cell	41	0.86	0.56	0.72	0.33	0.00	0.57	0.89	0.90	0.89
regulatory T cell	43	0.00	0.00	0.00	0.00	0.00	0.54	0.72	0.89	0.38
fibrocyte	35	0.00	0.00	0.16	0.26	0.00	0.68	0.79	0.90	0.89
pericyte	34	0.00	0.81	0.63	0.59	0.00	0.90	0.93	0.94	0.93
respiratory basal cell	30	0.00	0.00	0.78	0.59	0.00	0.53	0.95	0.95	0.98
plasma cell	23	0.16	0.00	0.30	0.00	0.00	0.21	0.52	0.39	0.35
club cell	20	0.00	0.10	0.33	0.53	0.00	0.79	1.00	0.91	0.79
kidney interstitial fibroblast	15	0.00	0.00	0.24	0.77	0.00	0.48	0.88	0.94	1.00
lymphoid lineage restricted progenitor cell	9	0.88	0.00	0.62	0.20	0.00	0.39	1.00	0.90	0.88
intermediate monocyte	12	0.00	0.00	0.00	0.00	0.00	0.76	0.80	1.00	0.15
lymphocyte	9	0.00	0.00	0.00	0.00	0.00	0.64	0.82	0.95	0.20
lung macrophage	9	0.00	0.00	0.00	0.00	0.00	0.32	0.82	0.82	0.88
plasmacytoid dendritic cell	6	0.00	0.00	0.00	0.00	0.00	0.35	0.39	0.67	0.00
lung neuroendocrine cell	4	0.00	0.00	0.00	0.00	0.00	0.89	1.00	1.00	1.00
pulmonary alveolar type 1 cell	4	0.00	0.00	0.40	0.00	0.00	0.40	1.00	1.00	1.00

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