grimage
Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.
Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.
| Predicts | mortality risk |
| Species | Homo sapiens |
| Tissue | whole blood |
| Data type | DNA methylation |
| Model type | two-stage elastic net + Cox regression |
| Year | 2019 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["grimage"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Lu, Ake T., et al. "DNA methylation GrimAge strongly predicts lifespan and healthspan." Aging (Albany NY) 11 (2019): 303β327.
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