grimage2packyrs

DNAm PACKYRS is a methylation surrogate for cumulative smoking exposure and a GrimAge component.

Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.

Predicts smoking exposure
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type elastic net regression
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["grimage2packyrs"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lu, A. T., et al. โ€œDNA methylation GrimAge version 2.โ€ Aging 14(23): 9484โ€“9549 (2022).

https://doi.org/10.18632/aging.204434

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