hrsinchphenoage

CpG-weighted HRS/InCHIANTI retraining of DNAm PhenoAge produced during the PC-clocks work; this implementation is not a principal-component clock.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts phenotypic age
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type weighted linear score
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["hrsinchphenoage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Higgins-Chen, Albert T., et al. "A computational solution for bolstering reliability of epigenetic clocks: implications for clinical trials and longitudinal tracking." Nature Aging 2 (2022): 644–661.

https://doi.org/10.1038/s43587-022-00248-2

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