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metadata
license: mit
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

mayne

Placental elastic-net clock trained on pooled healthy human placenta methylation datasets; 62 selected CpGs predict gestational age and were used to test age acceleration in early-onset preeclampsia.

Predicts gestational age
Species Homo sapiens
Tissue placenta
Data type DNA methylation
Model type elastic net regression
Year 2017

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["mayne"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Mayne, Benjamin T., et al. "Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation." Epigenomics 9 (2017): 279–289.

https://doi.org/10.2217/epi-2016-0103