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title: README
emoji: 馃К
colorFrom: green
colorTo: purple
sdk: static
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Doses AI - Private intelligence for medicine

Open medical intelligence, built to run locally.

Website  路  Flagship model  路  Technical report  路  Runtime

Featured release

Pestle-27B-Ternary-GGUF

A 27B open-weight medical model packaged as an 8.48 GB runnable GGUF. Pestle is designed for private local and on-premises systems spanning clinical knowledge, biomedical evidence work, pharmaceutical retrieval, and coding.

Apache 2.0 路 27B parameters 路 8.48 GB GGUF 路 CPU, Metal and CUDA

Weights and model card 路 Technical report 路 Run with mortar.cpp

Research

  • Low-bit model compression - ternary and compact representations for capable local models.
  • Medical model evaluation - matched benchmarking across clinical knowledge, biomedical QA, retrieval, and general capabilities.
  • Local inference - practical execution across CPU, Apple Silicon, and NVIDIA GPUs without a required cloud dependency.

Open source

Project What it is Links
Pestle-27B-Ternary Open-weight 27B medical research model Model 路 Report
mortar.cpp Local CPU, Metal, and CUDA runtime for Pestle GitHub

Research preview. Doses AI models are not medical devices and are not intended to replace qualified professional judgment. Contact: malik@doses.ai.