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<meta name="description" content="MulinLab research in population-aware DNA modeling, human genetic variation, and evolution.">
<title>MulinLab | hEvo</title>
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<img class="banner" src="https://raw.githubusercontent.com/mulinlab/hEVO/main/header.png" alt="hEvo: learning human genetic variation across populations and evolution" style="display:block;width:100%;height:auto;border-radius:12px;margin:0 0 18px">
<p class="eyebrow" style="margin:0 0 7px;color:#164c9a;font-size:12px;font-weight:bold;letter-spacing:1.4px">MULINLAB · POPULATION GENOMICS</p>
<h1 style="margin:0 0 10px;color:#142b52;font-size:30px;line-height:1.15">Human genetic variation, modeled through haplotypes.</h1>
<p class="intro" style="max-width:780px;margin:0 0 18px;color:#52637d;font-size:16px">hEvo learns DNA representations from population-scale haplotype sequence variation to support research in variant effects, regulatory annotation, ancestry, and evolution.</p>
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<a class="button primary" href="https://github.com/mulinlab/hEVO" style="display:inline-block;margin:0 7px 6px 0;padding:9px 13px;border:1px solid #164c9a;border-radius:8px;background:#164c9a;color:#fff;font-weight:bold;text-decoration:none">Explore code & workflows ↗</a>
<a class="button secondary" href="https://mulinlab-readme.static.hf.space/" style="display:inline-block;margin:0 7px 6px 0;padding:9px 13px;border:1px solid #d8e5f4;border-radius:8px;background:#f4f8fc;color:#164c9a;font-weight:bold;text-decoration:none">Open styled research page ↗</a>
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<p class="eyebrow" style="margin:0 0 4px;color:#007e86;font-size:12px;font-weight:bold;letter-spacing:1.4px">MODELS · DNA REPRESENTATIONS</p>
<h2 id="models-title" style="margin:0 0 5px;color:#142b52;font-size:22px;line-height:1.25">hEvo checkpoints</h2>
<p style="margin:0;color:#52637d;font-size:14px">Both model cards include DNA embedding and single-nucleotide likelihood examples.</p>
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<article class="card model-card" style="flex:1 1 220px;min-width:210px;margin:0 0 8px;padding:15px;border:1px solid #d8e5f4;border-radius:12px;background:#fff">
<p class="card-top" style="margin:0 0 10px;color:#164c9a;font-size:12px;font-weight:bold;letter-spacing:.6px">BASE · 87.1M PARAMETERS</p>
<h3 style="margin:0 0 7px;color:#142b52;font-size:19px">hEVO-base-o</h3>
<p style="margin:0 0 11px;color:#52637d;font-size:14px">1,024-nt context · masked language modeling · public 1000 Genomes Project and HGDP sequences.</p>
<a class="card-link" href="https://huggingface.co/MulinLab/hEVO-base-o" style="color:#164c9a;font-weight:bold;text-decoration:none">Read model card →</a>
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<article class="card model-card" style="flex:1 1 220px;min-width:210px;margin:0 0 8px;padding:15px;border:1px solid #d8e5f4;border-radius:12px;background:#fff">
<p class="card-top" style="margin:0 0 10px;color:#164c9a;font-size:12px;font-weight:bold;letter-spacing:.6px">LARGE · 319.5M PARAMETERS</p>
<h3 style="margin:0 0 7px;color:#142b52;font-size:19px">hEVO-large-o</h3>
<p style="margin:0 0 11px;color:#52637d;font-size:14px">1,024-nt context · masked language modeling · public 1000 Genomes Project and HGDP sequences.</p>
<a class="card-link" href="https://huggingface.co/MulinLab/hEVO-large-o" style="color:#164c9a;font-weight:bold;text-decoration:none">Read model card →</a>
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<article class="card data-card" style="flex:1 1 220px;min-width:210px;margin:0 0 8px;padding:15px;border:1px solid #ccebea;border-radius:12px;background:#f7fcfc">
<p class="card-top" style="margin:0 0 10px;color:#007e86;font-size:12px;font-weight:bold;letter-spacing:.6px">DATA · 15 TASK BUNDLES</p>
<h3 style="margin:0 0 7px;color:#142b52;font-size:19px">hEvo benchmarks</h3>
<p style="margin:0 0 11px;color:#52637d;font-size:14px">Frozen evaluation inputs or source downloaders, task-specific build scripts, and construction documentation.</p>
<a class="card-link" href="https://huggingface.co/datasets/MulinLab/hEvo-benchmarks" style="color:#007e86;font-weight:bold;text-decoration:none">Browse dataset card →</a>
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<aside class="access" aria-labelledby="access-title" style="margin:10px 0 0;padding:14px;border-left:4px solid #164c9a;border-radius:8px;background:#f1f7fd">
<h2 id="access-title" style="margin:0 0 5px;color:#142b52;font-size:16px">Peer-review access</h2>
<p style="margin:0;color:#52637d;font-size:14px">Model checkpoints and benchmark data are gated and manually reviewed by MulinLab for peer-review use. Request access on the relevant Hugging Face page. The <code>-o</code> suffix denotes public-data training; it does not imply an open-weights license. Dataset terms vary by source.</p>
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<footer style="margin:18px 0 0;padding:12px 0 0;border-top:1px solid #d8e5f4;color:#52637d;font-size:13px">Scientific workflows and source tables are maintained in the <a href="https://github.com/mulinlab/hEVO" style="color:#164c9a;font-weight:bold">hEvo GitHub repository</a>. · <a href="https://huggingface.co/MulinLab" style="color:#164c9a;font-weight:bold">MulinLab on Hugging Face ↗</a></footer>
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