| --- |
| title: MulinLab | hEvo |
| emoji: "🧬" |
| colorFrom: blue |
| colorTo: blue |
| sdk: static |
| short_description: Population-aware DNA modeling for human genomics |
| pinned: false |
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| |
| <div align="center"> |
| <img src="https://raw.githubusercontent.com/mulinlab/hEVO/main/header.png" alt="hEvo: learning human genetic variation across populations and evolution" width="100%"> |
| <h1>MulinLab</h1> |
| <p><strong>Population-aware DNA modeling for human genomics</strong></p> |
| <p>We study how human genetic diversity and haplotype sequence variation inform genome representation, variant effect, regulatory annotation, ancestry, and evolution.</p> |
| <p> |
| <a href="https://github.com/mulinlab/hEVO"><img src="https://img.shields.io/badge/GitHub-hEVO-181717?style=flat-square&logo=github" alt="hEVO source code on GitHub"></a> |
| <a href="https://huggingface.co/datasets/MulinLab/hEvo-benchmarks"><img src="https://img.shields.io/badge/Hugging%20Face-Benchmarks-FFD21E?style=flat-square&logo=huggingface&logoColor=000" alt="hEvo benchmark dataset on Hugging Face"></a> |
| </p> |
| </div> |
| |
| --- |
|
|
| ## Explore hEvo |
|
|
| | Resource | What it contains | Access | |
| |---|---|---| |
| | [hEVO-base-o](https://huggingface.co/MulinLab/hEVO-base-o) | 87.1M-parameter, 1,024-nt model trained with masked language modeling on public 1000 Genomes Project and HGDP sequences. | Manual approval for peer reviewers | |
| | [hEVO-large-o](https://huggingface.co/MulinLab/hEVO-large-o) | 319.5M-parameter model in the same public-data training family. | Manual approval for peer reviewers | |
| | [hEvo-benchmarks](https://huggingface.co/datasets/MulinLab/hEvo-benchmarks) | 15 task bundles with frozen inputs or source downloaders, task-specific build scripts, and documentation. | Manual approval for peer reviewers | |
| | [GitHub source repository](https://github.com/mulinlab/hEVO) | Training and benchmark workflows, configurations, result tables, figures, and reproduction guides. | Public repository | |
|
|
| The `-o` suffix identifies a public-data training variant. It does **not** mean that model weights are openly licensed. Model-weight licensing has not been confirmed. Benchmark files may carry different terms; follow the cited source publication and task documentation for each dataset. |
|
|
| ## How to get started |
|
|
| 1. **Choose a model or benchmark task** from the table above. |
| 2. **Request access** on the corresponding Hugging Face page. Model and dataset access is manually reviewed for peer-review use. |
| 3. **Use the card's quick start** after approval. The model cards include DNA embedding and single-nucleotide likelihood examples; the dataset card lists task-specific download and build instructions. |
| 4. **Reproduce the workflows** with the [GitHub guides](https://github.com/mulinlab/hEVO), which keep model code, evaluation workflows, and source result tables together. |
|
|
| ## Scientific context and citation |
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|
| The [GitHub repository](https://github.com/mulinlab/hEVO) describes the hEvo training stages, evaluation protocols, source tables, and figure workflows. For hEvo citation details, see the repository's [Citation section](https://github.com/mulinlab/hEVO#citation). |
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| For questions about access or scientific use, contact MulinLab through the relevant repository's Hugging Face discussion page. |
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