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analytics/feedback.csv

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 timestamp_utc,session_id,first_name,last_name,question,answer,rating,comment
-2025-09-15T15:39:35.937361+00:00,18d7d836-9d64-4cb7-ab69-6aa252b1bc76,Gaia,Dupont,How does sterilization of dECM influence mechanical properties of dECM gels?,"Answer: Sterilization methods can significantly affect the mechanical properties and biological activity of dEM. For example, gamma irradiation can lead to crosslinking of collagen fibers, altering its mechanical properties, while ethylene oxide can cause denaturation of proteins and loss of bioactivity. Therefore, it is essential to optimize the sterilizing conditions to minimize these effects and maintain the structural integrity and biological function of the dECMs. In addition, the use of additives such as antimicrobials and preservatives may further impact the mechanical and biological properties of the final constructs. The choice of sterilized method depends on the specific application and desired outcome. For instance, gelling agents like alginate and gelatin methacrylate can be used to enhance the mechanical strength of dEBM hydrogels, while preservatives like glutaraldehyde can improve shelf life but reduce cell viability. Ultimately, the optimal balance between sterilizability, mechanical properties (e.g., stiffness, viscoelasticity), and biological functionality must be achieved for effective tissue engineering applications.",5,
+2025-09-15T15:45:27.570321+00:00,ab04a1ad-f5f4-48db-a614-ff86d1a5b8c8,Maciej,Gusciora,is there anti fibrotic approved for tendinopathy?,"[LLM fallback — ungrounded]
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+There is currently no approved anti-fibrotic medication specifically for the treatment of tendinitis or tendinopathy. However, some drugs used off-label, such as pirfenidone and losartan, have shown potential benefits in reducing tendon scarring and inflammation. These medications are not FDA-approved for this indication, and their use should be based on individualized clinical judgment. The primary treatment for tendon injuries and tendinpathy remains rest, physical therapy, and surgery when necessary.",4,