Update the interface features and complete the API integration debugging.

clm-frontend-dev.py

@@ -1,32 +1,293 @@
 import gradio as gr
-from fastapi import FastAPI
+from fastapi import FastAPI, HTTPException
 from starlette.staticfiles import StaticFiles
 import uvicorn
 import logging
 from pydantic import BaseModel
 import pandas as pd
 import time
-from fastapi.responses import RedirectResponse
+import requests
+import json
+from typing import List, Dict, Any, Optional, Tuple
 
+# Set up logging configuration
 logging.basicConfig(level=logging.DEBUG, format='%(asctime)s - %(levelname)s - %(message)s')
 logger = logging.getLogger(__name__)
 
+# API configurations
+API_BASE_URL = "https://songyou-llm-fastapi.hf.space"
+FRAGMENT_ENDPOINT = f"{API_BASE_URL}/fragmentize"
+GENERATE_ENDPOINT = f"{API_BASE_URL}/generate"
+
+# Load parameters from configuration file
+try:
+    with open('param.json', 'r') as f:
+        params = json.load(f)
+    logger.info("Successfully loaded parameter configuration")
+except Exception as e:
+    logger.error(f"Error loading parameter configuration: {str(e)}")
+    raise
+
+# Data models
 class SmilesData(BaseModel):
+    """Model for SMILES data received from frontend"""
     smiles: str
 
+class GenerateRequest(BaseModel):
+    """Request model for generate endpoint with updated fields"""
+    constSmiles: str
+    varSmiles: str
+    mainCls: str
+    minorCls: str
+    deltaValue: str
+    targetName: str = "target1"  # default value
+    num: int
+
+
+
+
+
+
+
+
+
+# Helper functions for metric handling
+def get_metrics_for_objective(objective: str) -> List[str]:
+    """Get the corresponding metrics for a given objective"""
+    if objective == "None" or objective not in params["Metrics"]:
+        return ["None"]
+    return ["None"] + params["Metrics"].get(objective, [])
+
+def get_metric_full_name(objective: str, metric: str) -> str:
+    """
+    Constructs the full metric name based on objective and metric.
+    For general physical properties, returns just the metric name.
+    For others, returns the metric name as is.
+    """
+    if objective == "general physical properties":
+        return metric
+    return f"{metric}"
+
+def get_metric_type(metric_name: str) -> str:
+    """
+    Determines if a metric is boolean or sequential based on the BoolOrSeq mapping.
+    Returns 'bool', 'seq', or '' if not found.
+    """
+    metric_type = params["BoolOrSeq"].get(metric_name, "")
+    logger.debug(f"Metric type for {metric_name}: {metric_type}")
+    return metric_type
+
+def get_delta_choices(metric_type: str) -> List[str]:
+    """Returns the appropriate choices for delta value based on metric type."""
+    if metric_type == "bool":
+        return params["ImprovementAnticipationBool"]
+    elif metric_type == "seq":
+        return params["ImprovementAnticipationSeq"]
+    return []
+
+def validate_metric_combination(objective: str, metric: str) -> bool:
+    """
+    Validates if the objective-metric combination is valid.
+    Returns True if valid, False otherwise.
+    """
+    if objective == "None" or metric == "None":
+        logger.debug(f"Invalid objective or metric: {objective} - {metric}")
+        return False
+    if objective not in params["Metrics"]:
+        logger.debug(f"Objective not found in metrics: {objective}")
+        return False
+    if metric not in params["Metrics"].get(objective, []):
+        logger.debug(f"Metric not found in objective: {metric}")
+        return False
+    logger.debug(f"Valid metric combination: {objective} - {metric}")
+    return True
+
+def handle_generate_analogs(
+    main_cls: str,
+    minor_cls: str,
+    number: int,
+    bool_delta_val: str,
+    seq_delta_val: str,
+    const_smiles: str,
+    var_smiles: str,
+    metric_type: str
+) -> pd.DataFrame:
+    """
+    Handles the generation of analogs with appropriate delta value selection and error handling.
+    This function serves as the bridge between the UI and the generate_analogs API call.
+    
+    Args:
+        main_cls (str): The main objective classification
+        minor_cls (str): The specific metric
+        number (int): Number of analogs to generate
+        bool_delta_val (str): Selected delta value for boolean metrics
+        seq_delta_val (str): Selected delta value for sequential metrics
+        const_smiles (str): Constant fragment SMILES
+        var_smiles (str): Variable fragment SMILES
+        metric_type (str): Type of metric ('bool' or 'seq')
+    
+    Returns:
+        pd.DataFrame: DataFrame containing the generated analogs and their properties
+    """
+    try:
+        # Input validation
+        if not all([main_cls, minor_cls, const_smiles, var_smiles]):
+            logger.error("Missing required inputs")
+            return pd.DataFrame()
+            
+        if not validate_metric_combination(main_cls, minor_cls):
+            logger.error(f"Invalid metric combination: {main_cls} - {minor_cls}")
+            return pd.DataFrame()
+
+        # Select appropriate delta value based on metric type
+        if metric_type not in ["bool", "seq"]:
+            logger.error(f"Invalid metric type: {metric_type}")
+            return pd.DataFrame()
+            
+        delta_value = bool_delta_val if metric_type == "bool" else seq_delta_val
+        
+        # Generate analogs using the API
+        analogs_data = generate_analogs(
+            main_cls=main_cls,
+            minor_cls=minor_cls,
+            number=number,
+            delta_value=delta_value,
+            const_smiles=const_smiles,
+            var_smiles=var_smiles
+        )
+        
+        if not analogs_data:
+            logger.warning("No analogs generated")
+            return pd.DataFrame()
+            
+        return update_output_table(analogs_data)
+        
+    except Exception as e:
+        logger.error(f"Error in handle_generate_analogs: {str(e)}")
+        return pd.DataFrame()
+
+# Update the fragment_molecule function to handle the new response format
+def fragment_molecule(smiles: str) -> Tuple[str, str, str]:
+    """
+    Call the fragment API endpoint to get molecule fragments
+    Returns: List of fragments with their details
+    """
+    try:
+        logger.info(f"Calling fragment API with SMILES: {smiles}")
+        response = requests.get(f"{FRAGMENT_ENDPOINT}?smiles={smiles}")
+        response.raise_for_status()
+        data = response.json()
+        logger.info(f"Fragment API response: {data}")
+        
+        # Return empty values if no fragments found
+        if not data.get("fragments"):
+            return "", "", ""
+            
+        # Return the first fragment by default
+        first_fragment = data["fragments"][0]
+        return (
+            first_fragment.get("constant_smiles", ""),
+            first_fragment.get("variable_smiles", ""),
+            str(first_fragment.get("attachment_order", ""))
+        )
+    except Exception as e:
+        logger.error(f"Fragment API call failed: {str(e)}")
+        return "", "", ""
+
+def generate_analogs(
+    main_cls: str,
+    minor_cls: str,
+    number: int,
+    delta_value: str,
+    const_smiles: str,
+    var_smiles: str
+) -> List[Dict[str, Any]]:
+    """
+    Generate molecule analogs using the generate API endpoint with improved error handling
+    and validation.
+    """
+    try:
+        # Validate inputs
+        if not all([const_smiles, var_smiles, main_cls, minor_cls, delta_value]):
+            logger.error("Missing required inputs for generate_analogs")
+            return []
+
+        # Create API request
+        payload = GenerateRequest(
+            constSmiles=const_smiles,
+            varSmiles=var_smiles,
+            mainCls=main_cls if main_cls != "None" else "",
+            minorCls=minor_cls if minor_cls != "None" else "",
+            deltaValue=delta_value,
+            num=int(number)
+        )
+        
+        logger.info(f"Calling generate API with payload: {payload.dict()}")
+        
+        # Make API request
+        response = requests.post(
+            GENERATE_ENDPOINT,
+            headers={'Content-Type': 'application/json'},
+            json=payload.dict(),
+            timeout=30
+        )
+        
+        response.raise_for_status()
+        results = response.json()
+        
+        if not isinstance(results, list):
+            logger.error(f"Unexpected response format: {results}")
+            return []
+            
+        logger.info(f"Successfully generated {len(results)} analogs")
+        return results
+        
+    except requests.exceptions.Timeout:
+        logger.error("Generate API request timed out")
+        return []
+    except requests.exceptions.RequestException as e:
+        logger.error(f"Generate API request failed: {str(e)}")
+        return []
+    except Exception as e:
+        logger.error(f"Unexpected error in generate_analogs: {str(e)}")
+        return []
+
+def update_output_table(data: List[Dict[str, Any]]) -> pd.DataFrame:
+    """Convert API response data to pandas DataFrame for display"""
+    try:
+        df = pd.DataFrame(data)
+        return df
+    except Exception as e:
+        logger.error(f"Error creating DataFrame: {str(e)}")
+        return pd.DataFrame()
+
+def save_to_csv(data: pd.DataFrame, selected_only: bool = False) -> Optional[str]:
+    """Save data to CSV file"""
+    try:
+        filename = f"molecule_analogs_{int(time.time())}.csv"
+        data.to_csv(filename, index=False)
+        return filename
+    except Exception as e:
+        logger.error(f"Error saving to CSV: {str(e)}")
+        return None
+
+# FastAPI app initialization
 app = FastAPI()
 
-# 将 ketcher 目录挂载为静态资源，确保 ketcher/index.html 存在
+# Mount Ketcher static files
 app.mount("/ketcher", StaticFiles(directory="ketcher"), name="ketcher")
 
-# 接收前端发送的SMILES数据的接口
 @app.post("/update_smiles")
 async def update_smiles(data: SmilesData):
-    logger.info(f"Received SMILES from front-end: {data.smiles}")
-    print(f"[PRINT-Backend] Received SMILES from front-end: {data.smiles}")
-    return {"status": "ok", "received_smiles": data.smiles}
-
-# 前端嵌入的HTML和脚本
+    """Endpoint to receive SMILES data from frontend"""
+    try:
+        logger.info(f"Received SMILES from front-end: {data.smiles}")
+        return {"status": "ok", "received_smiles": data.smiles}
+    except Exception as e:
+        logger.error(f"Error processing SMILES update: {str(e)}")
+        raise HTTPException(status_code=500, detail=str(e))
+
+# Ketcher interface HTML template
 KETCHER_HTML = r'''
 <iframe id="ifKetcher" src="/ketcher/index.html" width="100%" height="600px" style="border: 1px solid #ccc;"></iframe>
 
@@ -50,7 +311,6 @@ function updateGradioInput(smiles) {
     const input = findSmilesInput();
     if (input && input.value !== smiles) {
         input.value = smiles;
-        // 手动触发input事件让 Gradio 更新状态
         input.dispatchEvent(new Event('input', { bubbles: true }));
         console.log("[Front-end] Updated Gradio input with SMILES:", smiles);
     }
@@ -65,8 +325,6 @@ async function handleKetcherChange() {
             lastSmiles = smiles;
             updateGradioInput(smiles);
 
-            // 将SMILES发送给后端 (可以保留，但可能不是核心需求)
-            console.log("[Front-end] Sending SMILES to backend...");
             fetch('/update_smiles', {
                 method: 'POST',
                 headers: {'Content-Type': 'application/json'},
@@ -102,7 +360,6 @@ function initKetcher() {
     ketcher = ketcherWindow.ketcher;
     console.log("[Front-end] Ketcher instance acquired:", ketcher);
 
-    // 设置初始分子
     ketcher.setMolecule('C').then(() => {
         console.log("[Front-end] Initial molecule set to 'C'.");
     });
@@ -110,7 +367,6 @@ function initKetcher() {
     const editor = ketcher.editor;
     console.log("[Front-end] Editor object:", editor);
 
-    // 尝试绑定变化事件
     let eventBound = false;
     if (editor && typeof editor.subscribe === 'function') {
         console.log("[Front-end] Using editor.subscribe('change', ...)");
@@ -130,39 +386,23 @@ document.getElementById('ifKetcher').addEventListener('load', () => {
 </script>
 '''
 
-# --- 模拟后端功能 (来自第二个版本) ---
-def smiles_to_structure(smiles):
-    """Dummy function"""
-    time.sleep(1)
-    return f"Structure Generated from: {smiles}"
-
-def fragment_molecule(smiles):
-    """Dummy function"""
-    time.sleep(2)
-    return "Fragment1", "Fragment2", "1-2"
-
-def generate_analogs(main_cls, minor_cls, number, delta_value):
-    """Dummy function"""
-    time.sleep(3)
-    return [
-        {"SMILE": "c1cccc1", "MolWt": 100, "TPSA": 20, "SLogP": 1, "SA": 30, "QED": 0.8},
-        {"SMILE": "c1ccccc1", "MolWt": 105, "TPSA": 25, "SLogP": 1.2, "SA": 32, "QED": 0.9},
-    ]
-
-def update_output_table(data):
-    df = pd.DataFrame(data)
-    return df
-
-# --- Gradio 界面 ---
 def create_combined_interface():
-    with gr.Blocks() as demo:
+    """
+    Creates the main Gradio interface combining Ketcher, molecule fragmentation,
+    and analog generation functionalities with fragment selection.
+    """
+    with gr.Blocks(theme=gr.themes.Default()) as demo:
         gr.Markdown("# Fragment Optimization Tools with Ketcher")
 
+        # Main layout with two columns
         with gr.Row():
+            # Left column - Ketcher editor
             with gr.Column(scale=2):
-                gr.HTML(KETCHER_HTML)  # 嵌入 Ketcher
+                gr.HTML(KETCHER_HTML)
 
+            # Right column - Controls and inputs
             with gr.Column(scale=1):
+                # SMILES Input section
                 with gr.Group():
                     gr.Markdown("### Input SMILES (From Ketcher)")
                     combined_smiles_input = gr.Textbox(
@@ -172,40 +412,222 @@ def create_combined_interface():
                         elem_id="combined_smiles_input"
                     )
                     with gr.Row():
-                        # 可以保留一个按钮来触发某些操作，例如手动同步
-                        get_ketcher_smiles_btn = gr.Button("Get SMILES from Ketcher")
-                        # 示例：将当前输入框的 SMILES 设置到 Ketcher (需要额外的前端 JavaScript)
-                        # set_ketcher_smiles_btn = gr.Button("Set SMILES to Ketcher")
-                        fragment_btn = gr.Button("Fragmentize Molecule")
+                        get_ketcher_smiles_btn = gr.Button("Get SMILES from Ketcher", variant="primary")
+                        fragment_btn = gr.Button("Find Fragments", variant="secondary")
 
+                # Fragment Selection section
+                # Fragment Selection section
+                # Fragment Selection section
+                with gr.Group():
+                    gr.Markdown("### Available Fragments")
+                    gr.Markdown("""
+                    Select a fragmentation pattern:
+                    - Variable Fragment: Part that will be modified
+                    - Constant Fragment: Part that remains unchanged
+                    - Order: Attachment point pattern between fragments
+                    """)
+                    fragments_table = gr.Dataframe(
+                        headers=["Variable Fragment", "Constant Fragment", "Order"],
+                        type="array",
+                        interactive=True,
+                        label="Click a row to select fragmentation pattern",
+                        # Remove the invalid parameters
+                        wrap=True,  # Allow text wrapping for long SMILES strings
+                        row_count=10  # Show 10 rows at a time
+    )
+
+                # Selected Fragment Display
                 with gr.Group():
+                    gr.Markdown("### Selected Fragment")
                     with gr.Row():
-                        constant_frag_input = gr.Textbox(label="Constant Fragment", placeholder="SMILES of constant fragment")
-                        variable_frag_input = gr.Textbox(label="Variable Fragment", placeholder="SMILES of variable fragment")
-                        attach_order_input = gr.Textbox(label="Attachment Order", placeholder="Attachment Order of SMILES")
-
+                        constant_frag_input = gr.Textbox(
+                            label="Constant Fragment",
+                            placeholder="SMILES of constant fragment",
+                            interactive=True
+                        )
+                        variable_frag_input = gr.Textbox(
+                            label="Variable Fragment",
+                            placeholder="SMILES of variable fragment",
+                            interactive=True
+                        )
+                        attach_order_input = gr.Textbox(
+                            label="Attachment Order",
+                            placeholder="Attachment Order",
+                            interactive=True
+                        )
+
+                # Analog generation section
                 with gr.Group():
-                    gr.Markdown("### Generate analogs")
+                    gr.Markdown("### Generate Analogs")
+                    current_metric_type = gr.State("")
+                    
                     with gr.Row():
-                        main_cls_dropdown = gr.Dropdown(label="Main Cls", choices=["None", "Cl", "Br"])
-                        minor_cls_dropdown = gr.Dropdown(label="Minor Cls", choices=["None", "Cl", "Br"])
-                        number_input = gr.Number(label="Number", value=5, step=1)
-
-                    delta_value_slider = gr.Slider(minimum=0, maximum=10, step=1, label="Delta Value", interactive=True)
-                    generate_analogs_btn = gr.Button("Generate")
+                        main_cls_dropdown = gr.Dropdown(
+                            label="Objective",
+                            choices=["None"] + params["Objective"],
+                            value="None"
+                        )
+                        minor_cls_dropdown = gr.Dropdown(
+                            label="Metrics",
+                            choices=["None"],
+                            value="None"
+                        )
+                        number_input = gr.Number(
+                            label="Number of Analogs",
+                            value=3,
+                            step=1,
+                            minimum=1,
+                            maximum=10
+                        )
 
+                    with gr.Row():
+                        bool_delta = gr.Dropdown(
+                            choices=params["ImprovementAnticipationBool"],
+                            label="Target Direction (Boolean)",
+                            value="0-1",
+                            visible=False,
+                            info="Select desired change direction"
+                        )
+                        seq_delta = gr.Dropdown(
+                            choices=params["ImprovementAnticipationSeq"],
+                            label="Target Range (Sequential)",
+                            value="(-0.5, 0.0]",
+                            visible=False,
+                            info="Select desired value range"
+                        )
+
+                    generate_analogs_btn = gr.Button("Generate Analogs", variant="primary")
+
+        # Results section
         with gr.Row():
             with gr.Column():
-                selected_columns = gr.CheckboxGroup(["SMILE", "MolWt", "TPSA", "SLogP", "SA", "QED"], value=["SMILE", "MolWt", "TPSA", "SLogP"], label="")
-
-        output_table = gr.Dataframe(headers=["SMILE", "MolWt", "TPSA", "SLogP", "SA", "QED"])
+                selected_columns = gr.CheckboxGroup(
+                    ["smile", "molWt", "tpsa", "slogp", "sa", "qed"],
+                    value=["smile", "molWt", "tpsa", "slogp"],
+                    label="Select Columns to Display"
+                )
+
+        output_table = gr.Dataframe(
+            headers=["smile", "molWt", "tpsa", "slogp", "sa", "qed"],
+            label="Generated Analogs"
+        )
 
         with gr.Row():
-            download_all_btn = gr.Button("Download All")
-            download_selected_btn = gr.Button("Download Selected")
-
-        # --- 事件处理 ---
-        # 当点击按钮时，手动从 Ketcher 获取 SMILES 并更新输入框
+            download_all_btn = gr.Button("Download All Results", variant="secondary")
+            download_selected_btn = gr.Button("Download Selected Results", variant="secondary")
+
+        # Helper functions for fragment handling
+        def process_fragments_response(response_data):
+            """Process the API response into table format"""
+            try:
+                fragments = response_data.get("fragments", [])
+                return [[
+                    fragment.get("variable_smiles", ""),
+                    fragment.get("constant_smiles", ""),
+                    str(fragment.get("attachment_order", ""))
+                ] for fragment in fragments]
+            except Exception as e:
+                logger.error(f"Error processing fragments: {str(e)}")
+                return []
+
+        def get_fragments(smiles: str):
+            """
+            Get and process fragments from API by calling the fragmentize endpoint.
+            Handles multiple fragmentation patterns returned by the API.
+            
+            Args:
+                smiles (str): Input SMILES string to fragmentize
+                
+            Returns:
+                list: A list of rows where each row represents a possible fragmentation pattern
+            """
+            try:
+                # URL encode the SMILES string to handle special characters
+                encoded_smiles = requests.utils.quote(smiles)
+                url = f"{FRAGMENT_ENDPOINT}?smiles={encoded_smiles}"
+                logger.info(f"Calling fragmentize API with URL: {url}")
+                
+                response = requests.get(url)
+                response.raise_for_status()
+                data = response.json()
+                
+                # Process fragments from the response
+                fragments = data.get('fragments', [])
+                logger.info(f"Found {len(fragments)} possible fragmentations")
+                
+                # Convert each fragment into a table row format
+                processed_fragments = []
+                for fragment in fragments:
+                    processed_fragments.append([
+                        fragment.get('variable_smiles', ''),
+                        fragment.get('constant_smiles', ''),
+                        str(fragment.get('attachment_order', ''))
+                    ])
+                
+                return processed_fragments
+                
+            except Exception as e:
+                logger.error(f"Error processing fragments: {str(e)}")
+                return []
+
+        def update_selected_fragment(evt: gr.SelectData, fragments_data):
+            """Update fragment fields when table row is selected"""
+            try:
+                if not fragments_data or evt.index[0] >= len(fragments_data):
+                    logger.warning("No valid fragment selected")
+                    return ["", "", ""]
+                    
+                selected = fragments_data[evt.index[0]]
+                logger.info(f"Selected fragment pattern {evt.index[0]}: var={selected[0]}, const={selected[1]}, order={selected[2]}")
+                return [selected[1], selected[0], selected[2]]
+                
+            except Exception as e:
+                logger.error(f"Error updating selected fragment: {str(e)}")
+                return ["", "", ""]
+            
+        def update_delta_inputs(objective: str, metric: str) -> dict:
+            """
+            Updates the visibility and options of delta inputs based on metric type.
+            Shows boolean or sequential delta input based on the metric's type.
+            
+            Args:
+                objective (str): The selected objective
+                metric (str): The selected metric
+            
+            Returns:
+                dict: Updates for both delta inputs and the current metric type
+            """
+            if not validate_metric_combination(objective, metric):
+                return {
+                    bool_delta: gr.update(visible=False),
+                    seq_delta: gr.update(visible=False),
+                    current_metric_type: ""
+                }
+
+            metric_name = get_metric_full_name(objective, metric)
+            metric_type = get_metric_type(metric_name)
+            
+            return {
+                bool_delta: gr.update(visible=metric_type == "bool"),
+                seq_delta: gr.update(visible=metric_type == "seq"),
+                current_metric_type: metric_type
+            }
+        
+        def update_metrics_dropdown(objective: str) -> dict:
+            """
+            Updates the metrics dropdown based on the selected objective.
+            Uses the get_metrics_for_objective helper function to get valid metrics for the chosen objective.
+            
+            Args:
+                objective (str): The selected objective from the main dropdown
+                
+            Returns:
+                dict: A Gradio update object containing the new dropdown configuration
+            """
+            metrics = get_metrics_for_objective(objective)
+            return gr.Dropdown(choices=metrics, value="None")
+
+        # Event handlers
         get_ketcher_smiles_btn.click(
             fn=None,
             inputs=None,
@@ -213,22 +635,72 @@ def create_combined_interface():
             js="async () => { const iframe = document.getElementById('ifKetcher'); if(iframe && iframe.contentWindow && iframe.contentWindow.ketcher) { const smiles = await iframe.contentWindow.ketcher.getSmiles(); return smiles; } else { console.error('Ketcher not ready'); return ''; } }"
         )
 
-        fragment_btn.click(fragment_molecule, inputs=combined_smiles_input, outputs=[constant_frag_input, variable_frag_input, attach_order_input])
+        # Fragment processing handlers
+        fragment_btn.click(
+            fn=get_fragments,
+            inputs=[combined_smiles_input],
+            outputs=[fragments_table]
+        )
+
+        fragments_table.select(
+            fn=update_selected_fragment,
+            inputs=[fragments_table],
+            outputs=[constant_frag_input, variable_frag_input, attach_order_input]
+        )
 
-        def update_table_with_analogs(main_cls, minor_cls, number, delta_value):
-            analogs_data = generate_analogs(main_cls, minor_cls, number, delta_value)
-            return update_output_table(analogs_data)
+        # Metric selection handlers
+        main_cls_dropdown.change(
+            fn=update_metrics_dropdown,
+            inputs=[main_cls_dropdown],
+            outputs=[minor_cls_dropdown]
+        )
 
-        generate_analogs_btn.click(update_table_with_analogs,
-                                  inputs=[main_cls_dropdown, minor_cls_dropdown, number_input, delta_value_slider],
-                                  outputs=output_table)
+        main_cls_dropdown.change(
+            fn=update_delta_inputs,
+            inputs=[main_cls_dropdown, minor_cls_dropdown],
+            outputs=[bool_delta, seq_delta, current_metric_type]
+        )
+        
+        minor_cls_dropdown.change(
+            fn=update_delta_inputs,
+            inputs=[main_cls_dropdown, minor_cls_dropdown],
+            outputs=[bool_delta, seq_delta, current_metric_type]
+        )
 
-        # TODO: 添加下载功能的回调
+        # Analog generation handler
+        generate_analogs_btn.click(
+            fn=handle_generate_analogs,
+            inputs=[
+                main_cls_dropdown,
+                minor_cls_dropdown,
+                number_input,
+                bool_delta,
+                seq_delta,
+                constant_frag_input,
+                variable_frag_input,
+                current_metric_type
+            ],
+            outputs=[output_table]
+        )
+
+        # Download handlers
+        download_all_btn.click(
+            lambda df: save_to_csv(df, False),
+            inputs=[output_table],
+            outputs=[gr.File(label="Download CSV")]
+        )
+
+        download_selected_btn.click(
+            lambda df, cols: save_to_csv(df[cols], True),
+            inputs=[output_table, selected_columns],
+            outputs=[gr.File(label="Download CSV")]
+        )
 
-    return demo
+        return demo
 
+# Mount the Gradio app
 combined_demo = create_combined_interface()
 app = gr.mount_gradio_app(app, combined_demo, path="/")
 
 if __name__ == "__main__":
-    uvicorn.run(app, host="0.0.0.0", port=7860)
+    uvicorn.run(app, host="127.0.0.1", port=6861)

param.json

@@ -0,0 +1,1428 @@
+{
+    "Objective": [
+        "activity",
+        "absorption",
+        "distribution",
+        "metabolism",
+        "excretion",
+        "toxicity",
+        "general physical properties"
+    ],
+    "ImprovementAnticipationBool": [
+        "0-1",
+        "1-0",
+        "0-0"
+    ],
+    "ImprovementAnticipationSeq": [
+        "(-inf, -10.5]",
+        "(-10.5, -8.5]",
+        "(-8.5, -6.5]",
+        "(-6.5, -4.5]",
+        "(-4.5, -2.5]",
+        "(-2.5, -1.5]",
+        "(-1.5, -1.0]",
+        "(-1.0, -0.5]",
+        "(-0.5, 0.0]",
+        "(0.0, 0.5]",
+        "(0.5, 1.0]",
+        "(1.0, 1.5]",
+        "(1.5, 2.5]",
+        "(2.5, 4.5]",
+        "(4.5, 6.5]",
+        "(6.5, 8.5]",
+        "(8.5, 10.5]",
+        "(10.5, inf]"
+    ],
+    "Metrics": {
+        "activity": [
+            "IC50",
+            "Ki",
+            "Kd",
+            "EC50"
+        ],
+        "absorption": [
+            "Drug uptake",
+            "Papp",
+            "permeability",
+            "F",
+            "Fu",
+            "Tmax",
+            "Cmax",
+            "lipophilicity_astrazeneca",
+            "solubility_aqsoldb",
+            "hydrationfreeenergy_freesolv",
+            "caco2_wang",
+            "pampa_ncats",
+            "hia_hou",
+            "pgp_broccatelli",
+            "bioavailability_ma"
+        ],
+        "distribution": [
+            "Vdss",
+            "Cp",
+            "vdss_lombardo",
+            "bbb_martins",
+            "ppbr_az"
+        ],
+        "metabolism": [
+            "Drug metabolism",
+            "LogD",
+            "LogP",
+            "cyp2c19_veith",
+            "cyp2d6_veith",
+            "cyp3a4_veith",
+            "cyp1a2_veith",
+            "cyp2c9_veith",
+            "cyp2c9_substrate_carbonmangels",
+            "cyp2d6_substrate_carbonmangels",
+            "cyp3a4_substrate_carbonmangels"
+        ],
+        "excretion": [
+            "AUC",
+            "CL",
+            "FC",
+            "half_life_obach",
+            "clearance_hepatocyte_az",
+            "clearance_microsome_az"
+        ],
+        "toxicity": [
+            "Stability",
+            "LD50",
+            "LC50",
+            "T1/2",
+            "tox21-NR-AR",
+            "tox21-NR-AR-LBD",
+            "tox21-NR-AhR",
+            "tox21-NR-Aromatase",
+            "tox21-NR-ER",
+            "tox21-NR-ER-LBD",
+            "tox21-NR-PPAR-gamma",
+            "tox21-SR-ARE",
+            "tox21-SR-ATAD5",
+            "tox21-SR-HSE",
+            "tox21-SR-MMP",
+            "tox21-SR-p53",
+            "toxcast-ACEA_T47D_80hr_Negative",
+            "toxcast-ACEA_T47D_80hr_Positive",
+            "toxcast-APR_HepG2_CellCycleArrest_24h_dn",
+            "toxcast-APR_HepG2_CellCycleArrest_24h_up",
+            "toxcast-APR_HepG2_CellCycleArrest_72h_dn",
+            "toxcast-APR_HepG2_CellLoss_24h_dn",
+            "toxcast-APR_HepG2_CellLoss_72h_dn",
+            "toxcast-APR_HepG2_MicrotubuleCSK_24h_dn",
+            "toxcast-APR_HepG2_MicrotubuleCSK_24h_up",
+            "toxcast-APR_HepG2_MicrotubuleCSK_72h_dn",
+            "toxcast-APR_HepG2_MicrotubuleCSK_72h_up",
+            "toxcast-APR_HepG2_MitoMass_24h_dn",
+            "toxcast-APR_HepG2_MitoMass_24h_up",
+            "toxcast-APR_HepG2_MitoMass_72h_dn",
+            "toxcast-APR_HepG2_MitoMass_72h_up",
+            "toxcast-APR_HepG2_MitoMembPot_1h_dn",
+            "toxcast-APR_HepG2_MitoMembPot_24h_dn",
+            "toxcast-APR_HepG2_MitoMembPot_72h_dn",
+            "toxcast-APR_HepG2_MitoticArrest_24h_up",
+            "toxcast-APR_HepG2_MitoticArrest_72h_up",
+            "toxcast-APR_HepG2_NuclearSize_24h_dn",
+            "toxcast-APR_HepG2_NuclearSize_72h_dn",
+            "toxcast-APR_HepG2_NuclearSize_72h_up",
+            "toxcast-APR_HepG2_OxidativeStress_24h_up",
+            "toxcast-APR_HepG2_OxidativeStress_72h_up",
+            "toxcast-APR_HepG2_StressKinase_1h_up",
+            "toxcast-APR_HepG2_StressKinase_24h_up",
+            "toxcast-APR_HepG2_StressKinase_72h_up",
+            "toxcast-APR_HepG2_p53Act_24h_up",
+            "toxcast-APR_HepG2_p53Act_72h_up",
+            "toxcast-APR_Hepat_Apoptosis_24hr_up",
+            "toxcast-APR_Hepat_Apoptosis_48hr_up",
+            "toxcast-APR_Hepat_CellLoss_24hr_dn",
+            "toxcast-APR_Hepat_CellLoss_48hr_dn",
+            "toxcast-APR_Hepat_DNADamage_24hr_up",
+            "toxcast-APR_Hepat_DNADamage_48hr_up",
+            "toxcast-APR_Hepat_DNATexture_24hr_up",
+            "toxcast-APR_Hepat_DNATexture_48hr_up",
+            "toxcast-APR_Hepat_MitoFxnI_1hr_dn",
+            "toxcast-APR_Hepat_MitoFxnI_24hr_dn",
+            "toxcast-APR_Hepat_MitoFxnI_48hr_dn",
+            "toxcast-APR_Hepat_NuclearSize_24hr_dn",
+            "toxcast-APR_Hepat_NuclearSize_48hr_dn",
+            "toxcast-APR_Hepat_Steatosis_24hr_up",
+            "toxcast-APR_Hepat_Steatosis_48hr_up",
+            "toxcast-ATG_AP_1_CIS_dn",
+            "toxcast-ATG_AP_1_CIS_up",
+            "toxcast-ATG_AP_2_CIS_dn",
+            "toxcast-ATG_AP_2_CIS_up",
+            "toxcast-ATG_AR_TRANS_dn",
+            "toxcast-ATG_AR_TRANS_up",
+            "toxcast-ATG_Ahr_CIS_dn",
+            "toxcast-ATG_Ahr_CIS_up",
+            "toxcast-ATG_BRE_CIS_dn",
+            "toxcast-ATG_BRE_CIS_up",
+            "toxcast-ATG_CAR_TRANS_dn",
+            "toxcast-ATG_CAR_TRANS_up",
+            "toxcast-ATG_CMV_CIS_dn",
+            "toxcast-ATG_CMV_CIS_up",
+            "toxcast-ATG_CRE_CIS_dn",
+            "toxcast-ATG_CRE_CIS_up",
+            "toxcast-ATG_C_EBP_CIS_dn",
+            "toxcast-ATG_C_EBP_CIS_up",
+            "toxcast-ATG_DR4_LXR_CIS_dn",
+            "toxcast-ATG_DR4_LXR_CIS_up",
+            "toxcast-ATG_DR5_CIS_dn",
+            "toxcast-ATG_DR5_CIS_up",
+            "toxcast-ATG_E2F_CIS_dn",
+            "toxcast-ATG_E2F_CIS_up",
+            "toxcast-ATG_EGR_CIS_up",
+            "toxcast-ATG_ERE_CIS_dn",
+            "toxcast-ATG_ERE_CIS_up",
+            "toxcast-ATG_ERRa_TRANS_dn",
+            "toxcast-ATG_ERRg_TRANS_dn",
+            "toxcast-ATG_ERRg_TRANS_up",
+            "toxcast-ATG_ERa_TRANS_up",
+            "toxcast-ATG_E_Box_CIS_dn",
+            "toxcast-ATG_E_Box_CIS_up",
+            "toxcast-ATG_Ets_CIS_dn",
+            "toxcast-ATG_Ets_CIS_up",
+            "toxcast-ATG_FXR_TRANS_up",
+            "toxcast-ATG_FoxA2_CIS_dn",
+            "toxcast-ATG_FoxA2_CIS_up",
+            "toxcast-ATG_FoxO_CIS_dn",
+            "toxcast-ATG_FoxO_CIS_up",
+            "toxcast-ATG_GAL4_TRANS_dn",
+            "toxcast-ATG_GATA_CIS_dn",
+            "toxcast-ATG_GATA_CIS_up",
+            "toxcast-ATG_GLI_CIS_dn",
+            "toxcast-ATG_GLI_CIS_up",
+            "toxcast-ATG_GRE_CIS_dn",
+            "toxcast-ATG_GRE_CIS_up",
+            "toxcast-ATG_GR_TRANS_dn",
+            "toxcast-ATG_GR_TRANS_up",
+            "toxcast-ATG_HIF1a_CIS_dn",
+            "toxcast-ATG_HIF1a_CIS_up",
+            "toxcast-ATG_HNF4a_TRANS_dn",
+            "toxcast-ATG_HNF4a_TRANS_up",
+            "toxcast-ATG_HNF6_CIS_dn",
+            "toxcast-ATG_HNF6_CIS_up",
+            "toxcast-ATG_HSE_CIS_dn",
+            "toxcast-ATG_HSE_CIS_up",
+            "toxcast-ATG_IR1_CIS_dn",
+            "toxcast-ATG_IR1_CIS_up",
+            "toxcast-ATG_ISRE_CIS_dn",
+            "toxcast-ATG_ISRE_CIS_up",
+            "toxcast-ATG_LXRa_TRANS_dn",
+            "toxcast-ATG_LXRa_TRANS_up",
+            "toxcast-ATG_LXRb_TRANS_dn",
+            "toxcast-ATG_LXRb_TRANS_up",
+            "toxcast-ATG_MRE_CIS_up",
+            "toxcast-ATG_M_06_TRANS_up",
+            "toxcast-ATG_M_19_CIS_dn",
+            "toxcast-ATG_M_19_TRANS_dn",
+            "toxcast-ATG_M_19_TRANS_up",
+            "toxcast-ATG_M_32_CIS_dn",
+            "toxcast-ATG_M_32_CIS_up",
+            "toxcast-ATG_M_32_TRANS_dn",
+            "toxcast-ATG_M_32_TRANS_up",
+            "toxcast-ATG_M_61_TRANS_up",
+            "toxcast-ATG_Myb_CIS_dn",
+            "toxcast-ATG_Myb_CIS_up",
+            "toxcast-ATG_Myc_CIS_dn",
+            "toxcast-ATG_Myc_CIS_up",
+            "toxcast-ATG_NFI_CIS_dn",
+            "toxcast-ATG_NFI_CIS_up",
+            "toxcast-ATG_NF_kB_CIS_dn",
+            "toxcast-ATG_NF_kB_CIS_up",
+            "toxcast-ATG_NRF1_CIS_dn",
+            "toxcast-ATG_NRF1_CIS_up",
+            "toxcast-ATG_NRF2_ARE_CIS_dn",
+            "toxcast-ATG_NRF2_ARE_CIS_up",
+            "toxcast-ATG_NURR1_TRANS_dn",
+            "toxcast-ATG_NURR1_TRANS_up",
+            "toxcast-ATG_Oct_MLP_CIS_dn",
+            "toxcast-ATG_Oct_MLP_CIS_up",
+            "toxcast-ATG_PBREM_CIS_dn",
+            "toxcast-ATG_PBREM_CIS_up",
+            "toxcast-ATG_PPARa_TRANS_dn",
+            "toxcast-ATG_PPARa_TRANS_up",
+            "toxcast-ATG_PPARd_TRANS_up",
+            "toxcast-ATG_PPARg_TRANS_up",
+            "toxcast-ATG_PPRE_CIS_dn",
+            "toxcast-ATG_PPRE_CIS_up",
+            "toxcast-ATG_PXRE_CIS_dn",
+            "toxcast-ATG_PXRE_CIS_up",
+            "toxcast-ATG_PXR_TRANS_dn",
+            "toxcast-ATG_PXR_TRANS_up",
+            "toxcast-ATG_Pax6_CIS_up",
+            "toxcast-ATG_RARa_TRANS_dn",
+            "toxcast-ATG_RARa_TRANS_up",
+            "toxcast-ATG_RARb_TRANS_dn",
+            "toxcast-ATG_RARb_TRANS_up",
+            "toxcast-ATG_RARg_TRANS_dn",
+            "toxcast-ATG_RARg_TRANS_up",
+            "toxcast-ATG_RORE_CIS_dn",
+            "toxcast-ATG_RORE_CIS_up",
+            "toxcast-ATG_RORb_TRANS_dn",
+            "toxcast-ATG_RORg_TRANS_dn",
+            "toxcast-ATG_RORg_TRANS_up",
+            "toxcast-ATG_RXRa_TRANS_dn",
+            "toxcast-ATG_RXRa_TRANS_up",
+            "toxcast-ATG_RXRb_TRANS_dn",
+            "toxcast-ATG_RXRb_TRANS_up",
+            "toxcast-ATG_SREBP_CIS_dn",
+            "toxcast-ATG_SREBP_CIS_up",
+            "toxcast-ATG_STAT3_CIS_dn",
+            "toxcast-ATG_STAT3_CIS_up",
+            "toxcast-ATG_Sox_CIS_dn",
+            "toxcast-ATG_Sox_CIS_up",
+            "toxcast-ATG_Sp1_CIS_dn",
+            "toxcast-ATG_Sp1_CIS_up",
+            "toxcast-ATG_TAL_CIS_dn",
+            "toxcast-ATG_TAL_CIS_up",
+            "toxcast-ATG_TA_CIS_dn",
+            "toxcast-ATG_TA_CIS_up",
+            "toxcast-ATG_TCF_b_cat_CIS_dn",
+            "toxcast-ATG_TCF_b_cat_CIS_up",
+            "toxcast-ATG_TGFb_CIS_dn",
+            "toxcast-ATG_TGFb_CIS_up",
+            "toxcast-ATG_THRa1_TRANS_dn",
+            "toxcast-ATG_THRa1_TRANS_up",
+            "toxcast-ATG_VDRE_CIS_dn",
+            "toxcast-ATG_VDRE_CIS_up",
+            "toxcast-ATG_VDR_TRANS_dn",
+            "toxcast-ATG_VDR_TRANS_up",
+            "toxcast-ATG_XTT_Cytotoxicity_up",
+            "toxcast-ATG_Xbp1_CIS_dn",
+            "toxcast-ATG_Xbp1_CIS_up",
+            "toxcast-ATG_p53_CIS_dn",
+            "toxcast-ATG_p53_CIS_up",
+            "toxcast-BSK_3C_Eselectin_down",
+            "toxcast-BSK_3C_HLADR_down",
+            "toxcast-BSK_3C_ICAM1_down",
+            "toxcast-BSK_3C_IL8_down",
+            "toxcast-BSK_3C_MCP1_down",
+            "toxcast-BSK_3C_MIG_down",
+            "toxcast-BSK_3C_Proliferation_down",
+            "toxcast-BSK_3C_SRB_down",
+            "toxcast-BSK_3C_Thrombomodulin_down",
+            "toxcast-BSK_3C_Thrombomodulin_up",
+            "toxcast-BSK_3C_TissueFactor_down",
+            "toxcast-BSK_3C_TissueFactor_up",
+            "toxcast-BSK_3C_VCAM1_down",
+            "toxcast-BSK_3C_Vis_down",
+            "toxcast-BSK_3C_uPAR_down",
+            "toxcast-BSK_4H_Eotaxin3_down",
+            "toxcast-BSK_4H_MCP1_down",
+            "toxcast-BSK_4H_Pselectin_down",
+            "toxcast-BSK_4H_Pselectin_up",
+            "toxcast-BSK_4H_SRB_down",
+            "toxcast-BSK_4H_VCAM1_down",
+            "toxcast-BSK_4H_VEGFRII_down",
+            "toxcast-BSK_4H_uPAR_down",
+            "toxcast-BSK_4H_uPAR_up",
+            "toxcast-BSK_BE3C_HLADR_down",
+            "toxcast-BSK_BE3C_IL1a_down",
+            "toxcast-BSK_BE3C_IP10_down",
+            "toxcast-BSK_BE3C_MIG_down",
+            "toxcast-BSK_BE3C_MMP1_down",
+            "toxcast-BSK_BE3C_MMP1_up",
+            "toxcast-BSK_BE3C_PAI1_down",
+            "toxcast-BSK_BE3C_SRB_down",
+            "toxcast-BSK_BE3C_TGFb1_down",
+            "toxcast-BSK_BE3C_tPA_down",
+            "toxcast-BSK_BE3C_uPAR_down",
+            "toxcast-BSK_BE3C_uPAR_up",
+            "toxcast-BSK_BE3C_uPA_down",
+            "toxcast-BSK_CASM3C_HLADR_down",
+            "toxcast-BSK_CASM3C_IL6_down",
+            "toxcast-BSK_CASM3C_IL6_up",
+            "toxcast-BSK_CASM3C_IL8_down",
+            "toxcast-BSK_CASM3C_LDLR_down",
+            "toxcast-BSK_CASM3C_LDLR_up",
+            "toxcast-BSK_CASM3C_MCP1_down",
+            "toxcast-BSK_CASM3C_MCP1_up",
+            "toxcast-BSK_CASM3C_MCSF_down",
+            "toxcast-BSK_CASM3C_MCSF_up",
+            "toxcast-BSK_CASM3C_MIG_down",
+            "toxcast-BSK_CASM3C_Proliferation_down",
+            "toxcast-BSK_CASM3C_Proliferation_up",
+            "toxcast-BSK_CASM3C_SAA_down",
+            "toxcast-BSK_CASM3C_SAA_up",
+            "toxcast-BSK_CASM3C_SRB_down",
+            "toxcast-BSK_CASM3C_Thrombomodulin_down",
+            "toxcast-BSK_CASM3C_Thrombomodulin_up",
+            "toxcast-BSK_CASM3C_TissueFactor_down",
+            "toxcast-BSK_CASM3C_VCAM1_down",
+            "toxcast-BSK_CASM3C_VCAM1_up",
+            "toxcast-BSK_CASM3C_uPAR_down",
+            "toxcast-BSK_CASM3C_uPAR_up",
+            "toxcast-BSK_KF3CT_ICAM1_down",
+            "toxcast-BSK_KF3CT_IL1a_down",
+            "toxcast-BSK_KF3CT_IP10_down",
+            "toxcast-BSK_KF3CT_IP10_up",
+            "toxcast-BSK_KF3CT_MCP1_down",
+            "toxcast-BSK_KF3CT_MCP1_up",
+            "toxcast-BSK_KF3CT_MMP9_down",
+            "toxcast-BSK_KF3CT_SRB_down",
+            "toxcast-BSK_KF3CT_TGFb1_down",
+            "toxcast-BSK_KF3CT_TIMP2_down",
+            "toxcast-BSK_KF3CT_uPA_down",
+            "toxcast-BSK_LPS_CD40_down",
+            "toxcast-BSK_LPS_Eselectin_down",
+            "toxcast-BSK_LPS_Eselectin_up",
+            "toxcast-BSK_LPS_IL1a_down",
+            "toxcast-BSK_LPS_IL1a_up",
+            "toxcast-BSK_LPS_IL8_down",
+            "toxcast-BSK_LPS_IL8_up",
+            "toxcast-BSK_LPS_MCP1_down",
+            "toxcast-BSK_LPS_MCSF_down",
+            "toxcast-BSK_LPS_PGE2_down",
+            "toxcast-BSK_LPS_PGE2_up",
+            "toxcast-BSK_LPS_SRB_down",
+            "toxcast-BSK_LPS_TNFa_down",
+            "toxcast-BSK_LPS_TNFa_up",
+            "toxcast-BSK_LPS_TissueFactor_down",
+            "toxcast-BSK_LPS_TissueFactor_up",
+            "toxcast-BSK_LPS_VCAM1_down",
+            "toxcast-BSK_SAg_CD38_down",
+            "toxcast-BSK_SAg_CD40_down",
+            "toxcast-BSK_SAg_CD69_down",
+            "toxcast-BSK_SAg_Eselectin_down",
+            "toxcast-BSK_SAg_Eselectin_up",
+            "toxcast-BSK_SAg_IL8_down",
+            "toxcast-BSK_SAg_IL8_up",
+            "toxcast-BSK_SAg_MCP1_down",
+            "toxcast-BSK_SAg_MIG_down",
+            "toxcast-BSK_SAg_PBMCCytotoxicity_down",
+            "toxcast-BSK_SAg_PBMCCytotoxicity_up",
+            "toxcast-BSK_SAg_Proliferation_down",
+            "toxcast-BSK_SAg_SRB_down",
+            "toxcast-BSK_hDFCGF_CollagenIII_down",
+            "toxcast-BSK_hDFCGF_EGFR_down",
+            "toxcast-BSK_hDFCGF_EGFR_up",
+            "toxcast-BSK_hDFCGF_IL8_down",
+            "toxcast-BSK_hDFCGF_IP10_down",
+            "toxcast-BSK_hDFCGF_MCSF_down",
+            "toxcast-BSK_hDFCGF_MIG_down",
+            "toxcast-BSK_hDFCGF_MMP1_down",
+            "toxcast-BSK_hDFCGF_MMP1_up",
+            "toxcast-BSK_hDFCGF_PAI1_down",
+            "toxcast-BSK_hDFCGF_Proliferation_down",
+            "toxcast-BSK_hDFCGF_SRB_down",
+            "toxcast-BSK_hDFCGF_TIMP1_down",
+            "toxcast-BSK_hDFCGF_VCAM1_down",
+            "toxcast-CEETOX_H295R_11DCORT_dn",
+            "toxcast-CEETOX_H295R_ANDR_dn",
+            "toxcast-CEETOX_H295R_CORTISOL_dn",
+            "toxcast-CEETOX_H295R_DOC_dn",
+            "toxcast-CEETOX_H295R_DOC_up",
+            "toxcast-CEETOX_H295R_ESTRADIOL_dn",
+            "toxcast-CEETOX_H295R_ESTRADIOL_up",
+            "toxcast-CEETOX_H295R_ESTRONE_dn",
+            "toxcast-CEETOX_H295R_ESTRONE_up",
+            "toxcast-CEETOX_H295R_OHPREG_up",
+            "toxcast-CEETOX_H295R_OHPROG_dn",
+            "toxcast-CEETOX_H295R_OHPROG_up",
+            "toxcast-CEETOX_H295R_PROG_up",
+            "toxcast-CEETOX_H295R_TESTO_dn",
+            "toxcast-CLD_ABCB1_48hr",
+            "toxcast-CLD_ABCG2_48hr",
+            "toxcast-CLD_CYP1A1_24hr",
+            "toxcast-CLD_CYP1A1_48hr",
+            "toxcast-CLD_CYP1A1_6hr",
+            "toxcast-CLD_CYP1A2_24hr",
+            "toxcast-CLD_CYP1A2_48hr",
+            "toxcast-CLD_CYP1A2_6hr",
+            "toxcast-CLD_CYP2B6_24hr",
+            "toxcast-CLD_CYP2B6_48hr",
+            "toxcast-CLD_CYP2B6_6hr",
+            "toxcast-CLD_CYP3A4_24hr",
+            "toxcast-CLD_CYP3A4_48hr",
+            "toxcast-CLD_CYP3A4_6hr",
+            "toxcast-CLD_GSTA2_48hr",
+            "toxcast-CLD_SULT2A_24hr",
+            "toxcast-CLD_SULT2A_48hr",
+            "toxcast-CLD_UGT1A1_24hr",
+            "toxcast-CLD_UGT1A1_48hr",
+            "toxcast-NCCT_HEK293T_CellTiterGLO",
+            "toxcast-NCCT_QuantiLum_inhib_2_dn",
+            "toxcast-NCCT_QuantiLum_inhib_dn",
+            "toxcast-NCCT_TPO_AUR_dn",
+            "toxcast-NCCT_TPO_GUA_dn",
+            "toxcast-NHEERL_ZF_144hpf_TERATOSCORE_up",
+            "toxcast-NVS_ADME_hCYP19A1",
+            "toxcast-NVS_ADME_hCYP1A1",
+            "toxcast-NVS_ADME_hCYP1A2",
+            "toxcast-NVS_ADME_hCYP2A6",
+            "toxcast-NVS_ADME_hCYP2B6",
+            "toxcast-NVS_ADME_hCYP2C19",
+            "toxcast-NVS_ADME_hCYP2C9",
+            "toxcast-NVS_ADME_hCYP2D6",
+            "toxcast-NVS_ADME_hCYP3A4",
+            "toxcast-NVS_ADME_hCYP4F12",
+            "toxcast-NVS_ADME_rCYP2C12",
+            "toxcast-NVS_ENZ_hAChE",
+            "toxcast-NVS_ENZ_hAMPKa1",
+            "toxcast-NVS_ENZ_hAurA",
+            "toxcast-NVS_ENZ_hBACE",
+            "toxcast-NVS_ENZ_hCASP5",
+            "toxcast-NVS_ENZ_hCK1D",
+            "toxcast-NVS_ENZ_hDUSP3",
+            "toxcast-NVS_ENZ_hES",
+            "toxcast-NVS_ENZ_hElastase",
+            "toxcast-NVS_ENZ_hFGFR1",
+            "toxcast-NVS_ENZ_hGSK3b",
+            "toxcast-NVS_ENZ_hMMP1",
+            "toxcast-NVS_ENZ_hMMP13",
+            "toxcast-NVS_ENZ_hMMP2",
+            "toxcast-NVS_ENZ_hMMP3",
+            "toxcast-NVS_ENZ_hMMP7",
+            "toxcast-NVS_ENZ_hMMP9",
+            "toxcast-NVS_ENZ_hPDE10",
+            "toxcast-NVS_ENZ_hPDE4A1",
+            "toxcast-NVS_ENZ_hPDE5",
+            "toxcast-NVS_ENZ_hPI3Ka",
+            "toxcast-NVS_ENZ_hPTEN",
+            "toxcast-NVS_ENZ_hPTPN11",
+            "toxcast-NVS_ENZ_hPTPN12",
+            "toxcast-NVS_ENZ_hPTPN13",
+            "toxcast-NVS_ENZ_hPTPN9",
+            "toxcast-NVS_ENZ_hPTPRC",
+            "toxcast-NVS_ENZ_hSIRT1",
+            "toxcast-NVS_ENZ_hSIRT2",
+            "toxcast-NVS_ENZ_hTrkA",
+            "toxcast-NVS_ENZ_hVEGFR2",
+            "toxcast-NVS_ENZ_oCOX1",
+            "toxcast-NVS_ENZ_oCOX2",
+            "toxcast-NVS_ENZ_rAChE",
+            "toxcast-NVS_ENZ_rCNOS",
+            "toxcast-NVS_ENZ_rMAOAC",
+            "toxcast-NVS_ENZ_rMAOAP",
+            "toxcast-NVS_ENZ_rMAOBC",
+            "toxcast-NVS_ENZ_rMAOBP",
+            "toxcast-NVS_ENZ_rabI2C",
+            "toxcast-NVS_GPCR_bAdoR_NonSelective",
+            "toxcast-NVS_GPCR_bDR_NonSelective",
+            "toxcast-NVS_GPCR_g5HT4",
+            "toxcast-NVS_GPCR_gH2",
+            "toxcast-NVS_GPCR_gLTB4",
+            "toxcast-NVS_GPCR_gLTD4",
+            "toxcast-NVS_GPCR_gMPeripheral_NonSelective",
+            "toxcast-NVS_GPCR_gOpiateK",
+            "toxcast-NVS_GPCR_h5HT2A",
+            "toxcast-NVS_GPCR_h5HT5A",
+            "toxcast-NVS_GPCR_h5HT6",
+            "toxcast-NVS_GPCR_h5HT7",
+            "toxcast-NVS_GPCR_hAT1",
+            "toxcast-NVS_GPCR_hAdoRA1",
+            "toxcast-NVS_GPCR_hAdoRA2a",
+            "toxcast-NVS_GPCR_hAdra2A",
+            "toxcast-NVS_GPCR_hAdra2C",
+            "toxcast-NVS_GPCR_hAdrb1",
+            "toxcast-NVS_GPCR_hAdrb2",
+            "toxcast-NVS_GPCR_hAdrb3",
+            "toxcast-NVS_GPCR_hDRD1",
+            "toxcast-NVS_GPCR_hDRD2s",
+            "toxcast-NVS_GPCR_hDRD4.4",
+            "toxcast-NVS_GPCR_hH1",
+            "toxcast-NVS_GPCR_hLTB4_BLT1",
+            "toxcast-NVS_GPCR_hM1",
+            "toxcast-NVS_GPCR_hM2",
+            "toxcast-NVS_GPCR_hM3",
+            "toxcast-NVS_GPCR_hM4",
+            "toxcast-NVS_GPCR_hNK2",
+            "toxcast-NVS_GPCR_hOpiate_D1",
+            "toxcast-NVS_GPCR_hOpiate_mu",
+            "toxcast-NVS_GPCR_hTXA2",
+            "toxcast-NVS_GPCR_p5HT2C",
+            "toxcast-NVS_GPCR_r5HT1_NonSelective",
+            "toxcast-NVS_GPCR_r5HT_NonSelective",
+            "toxcast-NVS_GPCR_rAdra1B",
+            "toxcast-NVS_GPCR_rAdra1_NonSelective",
+            "toxcast-NVS_GPCR_rAdra2_NonSelective",
+            "toxcast-NVS_GPCR_rAdrb_NonSelective",
+            "toxcast-NVS_GPCR_rNK1",
+            "toxcast-NVS_GPCR_rNK3",
+            "toxcast-NVS_GPCR_rOpiate_NonSelective",
+            "toxcast-NVS_GPCR_rOpiate_NonSelectiveNa",
+            "toxcast-NVS_GPCR_rSST",
+            "toxcast-NVS_GPCR_rTRH",
+            "toxcast-NVS_GPCR_rV1",
+            "toxcast-NVS_GPCR_rabPAF",
+            "toxcast-NVS_GPCR_rmAdra2B",
+            "toxcast-NVS_IC_hKhERGCh",
+            "toxcast-NVS_IC_rCaBTZCHL",
+            "toxcast-NVS_IC_rCaDHPRCh_L",
+            "toxcast-NVS_IC_rNaCh_site2",
+            "toxcast-NVS_LGIC_bGABARa1",
+            "toxcast-NVS_LGIC_h5HT3",
+            "toxcast-NVS_LGIC_hNNR_NBungSens",
+            "toxcast-NVS_LGIC_rGABAR_NonSelective",
+            "toxcast-NVS_LGIC_rNNR_BungSens",
+            "toxcast-NVS_MP_hPBR",
+            "toxcast-NVS_MP_rPBR",
+            "toxcast-NVS_NR_bER",
+            "toxcast-NVS_NR_bPR",
+            "toxcast-NVS_NR_cAR",
+            "toxcast-NVS_NR_hAR",
+            "toxcast-NVS_NR_hCAR_Antagonist",
+            "toxcast-NVS_NR_hER",
+            "toxcast-NVS_NR_hFXR_Agonist",
+            "toxcast-NVS_NR_hFXR_Antagonist",
+            "toxcast-NVS_NR_hGR",
+            "toxcast-NVS_NR_hPPARa",
+            "toxcast-NVS_NR_hPPARg",
+            "toxcast-NVS_NR_hPR",
+            "toxcast-NVS_NR_hPXR",
+            "toxcast-NVS_NR_hRAR_Antagonist",
+            "toxcast-NVS_NR_hRARa_Agonist",
+            "toxcast-NVS_NR_hTRa_Antagonist",
+            "toxcast-NVS_NR_mERa",
+            "toxcast-NVS_NR_rAR",
+            "toxcast-NVS_NR_rMR",
+            "toxcast-NVS_OR_gSIGMA_NonSelective",
+            "toxcast-NVS_TR_gDAT",
+            "toxcast-NVS_TR_hAdoT",
+            "toxcast-NVS_TR_hDAT",
+            "toxcast-NVS_TR_hNET",
+            "toxcast-NVS_TR_hSERT",
+            "toxcast-NVS_TR_rNET",
+            "toxcast-NVS_TR_rSERT",
+            "toxcast-NVS_TR_rVMAT2",
+            "toxcast-OT_AR_ARELUC_AG_1440",
+            "toxcast-OT_AR_ARSRC1_0480",
+            "toxcast-OT_AR_ARSRC1_0960",
+            "toxcast-OT_ER_ERaERa_0480",
+            "toxcast-OT_ER_ERaERa_1440",
+            "toxcast-OT_ER_ERaERb_0480",
+            "toxcast-OT_ER_ERaERb_1440",
+            "toxcast-OT_ER_ERbERb_0480",
+            "toxcast-OT_ER_ERbERb_1440",
+            "toxcast-OT_ERa_EREGFP_0120",
+            "toxcast-OT_ERa_EREGFP_0480",
+            "toxcast-OT_FXR_FXRSRC1_0480",
+            "toxcast-OT_FXR_FXRSRC1_1440",
+            "toxcast-OT_NURR1_NURR1RXRa_0480",
+            "toxcast-OT_NURR1_NURR1RXRa_1440",
+            "toxcast-TOX21_ARE_BLA_Agonist_ch1",
+            "toxcast-TOX21_ARE_BLA_Agonist_ch2",
+            "toxcast-TOX21_ARE_BLA_agonist_ratio",
+            "toxcast-TOX21_ARE_BLA_agonist_viability",
+            "toxcast-TOX21_AR_BLA_Agonist_ch1",
+            "toxcast-TOX21_AR_BLA_Agonist_ch2",
+            "toxcast-TOX21_AR_BLA_Agonist_ratio",
+            "toxcast-TOX21_AR_BLA_Antagonist_ch1",
+            "toxcast-TOX21_AR_BLA_Antagonist_ch2",
+            "toxcast-TOX21_AR_BLA_Antagonist_ratio",
+            "toxcast-TOX21_AR_BLA_Antagonist_viability",
+            "toxcast-TOX21_AR_LUC_MDAKB2_Agonist",
+            "toxcast-TOX21_AR_LUC_MDAKB2_Antagonist",
+            "toxcast-TOX21_AR_LUC_MDAKB2_Antagonist2",
+            "toxcast-TOX21_AhR_LUC_Agonist",
+            "toxcast-TOX21_Aromatase_Inhibition",
+            "toxcast-TOX21_AutoFluor_HEK293_Cell_blue",
+            "toxcast-TOX21_AutoFluor_HEK293_Media_blue",
+            "toxcast-TOX21_AutoFluor_HEPG2_Cell_blue",
+            "toxcast-TOX21_AutoFluor_HEPG2_Cell_green",
+            "toxcast-TOX21_AutoFluor_HEPG2_Media_blue",
+            "toxcast-TOX21_AutoFluor_HEPG2_Media_green",
+            "toxcast-TOX21_ELG1_LUC_Agonist",
+            "toxcast-TOX21_ERa_BLA_Agonist_ch1",
+            "toxcast-TOX21_ERa_BLA_Agonist_ch2",
+            "toxcast-TOX21_ERa_BLA_Agonist_ratio",
+            "toxcast-TOX21_ERa_BLA_Antagonist_ch1",
+            "toxcast-TOX21_ERa_BLA_Antagonist_ch2",
+            "toxcast-TOX21_ERa_BLA_Antagonist_ratio",
+            "toxcast-TOX21_ERa_BLA_Antagonist_viability",
+            "toxcast-TOX21_ERa_LUC_BG1_Agonist",
+            "toxcast-TOX21_ERa_LUC_BG1_Antagonist",
+            "toxcast-TOX21_ESRE_BLA_ch1",
+            "toxcast-TOX21_ESRE_BLA_ch2",
+            "toxcast-TOX21_ESRE_BLA_ratio",
+            "toxcast-TOX21_ESRE_BLA_viability",
+            "toxcast-TOX21_FXR_BLA_Antagonist_ch1",
+            "toxcast-TOX21_FXR_BLA_Antagonist_ch2",
+            "toxcast-TOX21_FXR_BLA_agonist_ch2",
+            "toxcast-TOX21_FXR_BLA_agonist_ratio",
+            "toxcast-TOX21_FXR_BLA_antagonist_ratio",
+            "toxcast-TOX21_FXR_BLA_antagonist_viability",
+            "toxcast-TOX21_GR_BLA_Agonist_ch1",
+            "toxcast-TOX21_GR_BLA_Agonist_ch2",
+            "toxcast-TOX21_GR_BLA_Agonist_ratio",
+            "toxcast-TOX21_GR_BLA_Antagonist_ch2",
+            "toxcast-TOX21_GR_BLA_Antagonist_ratio",
+            "toxcast-TOX21_GR_BLA_Antagonist_viability",
+            "toxcast-TOX21_HSE_BLA_agonist_ch1",
+            "toxcast-TOX21_HSE_BLA_agonist_ch2",
+            "toxcast-TOX21_HSE_BLA_agonist_ratio",
+            "toxcast-TOX21_HSE_BLA_agonist_viability",
+            "toxcast-TOX21_MMP_ratio_down",
+            "toxcast-TOX21_MMP_ratio_up",
+            "toxcast-TOX21_MMP_viability",
+            "toxcast-TOX21_NFkB_BLA_agonist_ch1",
+            "toxcast-TOX21_NFkB_BLA_agonist_ch2",
+            "toxcast-TOX21_NFkB_BLA_agonist_ratio",
+            "toxcast-TOX21_NFkB_BLA_agonist_viability",
+            "toxcast-TOX21_PPARd_BLA_Agonist_viability",
+            "toxcast-TOX21_PPARd_BLA_Antagonist_ch1",
+            "toxcast-TOX21_PPARd_BLA_agonist_ch1",
+            "toxcast-TOX21_PPARd_BLA_agonist_ch2",
+            "toxcast-TOX21_PPARd_BLA_agonist_ratio",
+            "toxcast-TOX21_PPARd_BLA_antagonist_ratio",
+            "toxcast-TOX21_PPARd_BLA_antagonist_viability",
+            "toxcast-TOX21_PPARg_BLA_Agonist_ch1",
+            "toxcast-TOX21_PPARg_BLA_Agonist_ch2",
+            "toxcast-TOX21_PPARg_BLA_Agonist_ratio",
+            "toxcast-TOX21_PPARg_BLA_Antagonist_ch1",
+            "toxcast-TOX21_PPARg_BLA_antagonist_ratio",
+            "toxcast-TOX21_PPARg_BLA_antagonist_viability",
+            "toxcast-TOX21_TR_LUC_GH3_Agonist",
+            "toxcast-TOX21_TR_LUC_GH3_Antagonist",
+            "toxcast-TOX21_VDR_BLA_Agonist_viability",
+            "toxcast-TOX21_VDR_BLA_Antagonist_ch1",
+            "toxcast-TOX21_VDR_BLA_agonist_ch2",
+            "toxcast-TOX21_VDR_BLA_agonist_ratio",
+            "toxcast-TOX21_VDR_BLA_antagonist_ratio",
+            "toxcast-TOX21_VDR_BLA_antagonist_viability",
+            "toxcast-TOX21_p53_BLA_p1_ch1",
+            "toxcast-TOX21_p53_BLA_p1_ch2",
+            "toxcast-TOX21_p53_BLA_p1_ratio",
+            "toxcast-TOX21_p53_BLA_p1_viability",
+            "toxcast-TOX21_p53_BLA_p2_ch1",
+            "toxcast-TOX21_p53_BLA_p2_ch2",
+            "toxcast-TOX21_p53_BLA_p2_ratio",
+            "toxcast-TOX21_p53_BLA_p2_viability",
+            "toxcast-TOX21_p53_BLA_p3_ch1",
+            "toxcast-TOX21_p53_BLA_p3_ch2",
+            "toxcast-TOX21_p53_BLA_p3_ratio",
+            "toxcast-TOX21_p53_BLA_p3_viability",
+            "toxcast-TOX21_p53_BLA_p4_ch1",
+            "toxcast-TOX21_p53_BLA_p4_ch2",
+            "toxcast-TOX21_p53_BLA_p4_ratio",
+            "toxcast-TOX21_p53_BLA_p4_viability",
+            "toxcast-TOX21_p53_BLA_p5_ch1",
+            "toxcast-TOX21_p53_BLA_p5_ch2",
+            "toxcast-TOX21_p53_BLA_p5_ratio",
+            "toxcast-TOX21_p53_BLA_p5_viability",
+            "toxcast-Tanguay_ZF_120hpf_AXIS_up",
+            "toxcast-Tanguay_ZF_120hpf_ActivityScore",
+            "toxcast-Tanguay_ZF_120hpf_BRAI_up",
+            "toxcast-Tanguay_ZF_120hpf_CFIN_up",
+            "toxcast-Tanguay_ZF_120hpf_CIRC_up",
+            "toxcast-Tanguay_ZF_120hpf_EYE_up",
+            "toxcast-Tanguay_ZF_120hpf_JAW_up",
+            "toxcast-Tanguay_ZF_120hpf_MORT_up",
+            "toxcast-Tanguay_ZF_120hpf_OTIC_up",
+            "toxcast-Tanguay_ZF_120hpf_PE_up",
+            "toxcast-Tanguay_ZF_120hpf_PFIN_up",
+            "toxcast-Tanguay_ZF_120hpf_PIG_up",
+            "toxcast-Tanguay_ZF_120hpf_SNOU_up",
+            "toxcast-Tanguay_ZF_120hpf_SOMI_up",
+            "toxcast-Tanguay_ZF_120hpf_SWIM_up",
+            "toxcast-Tanguay_ZF_120hpf_TRUN_up",
+            "toxcast-Tanguay_ZF_120hpf_TR_up",
+            "toxcast-Tanguay_ZF_120hpf_YSE_up",
+            "clintox",
+            "herg",
+            "herg_central-hERG_at_1uM",
+            "herg_central-hERG_at_10uM",
+            "herg_central-hERG_inhib",
+            "dili",
+            "skin_reaction",
+            "ames",
+            "carcinogens_lagunin",
+            "ld50_zhu"
+        ],
+        "general physical properties": [
+            "solubility",
+            "Thermal melting change",
+            "pKa"
+        ]
+    },
+    "BoolOrSeq": {
+        "T1-2": "seq",
+        "F": "bool",
+        "permeability": "seq",
+        "Stability": "seq",
+        "Drug metabolism": "seq",
+        "Cp": "seq",
+        "Cmax": "seq",
+        "FC": "seq",
+        "CL": "seq",
+        "Tmax": "bool",
+        "LD50": "seq",
+        "EC50": "seq",
+        "Drug uptake": "seq",
+        "Thermal melting change": "seq",
+        "solubility": "bool",
+        "LogD": "bool",
+        "LogP": "bool",
+        "Fu": "bool",
+        "pKa": "bool",
+        "Kd": "seq",
+        "Vdss": "bool",
+        "AUC": "seq",
+        "Ki": "seq",
+        "IC50": "seq",
+        "Papp": "seq",
+        "LC50": "seq",
+        "lipophilicity_astrazeneca": "seq",
+        "solubility_aqsoldb": "seq",
+        "hydrationfreeenergy_freesolv": "seq",
+        "caco2_wang": "seq",
+        "pampa_ncats": "bool",
+        "hia_hou": "bool",
+        "pgp_broccatelli": "bool",
+        "bioavailability_ma": "bool",
+        "vdss_lombardo": "seq",
+        "cyp2c19_veith": "bool",
+        "cyp2d6_veith": "bool",
+        "cyp3a4_veith": "bool",
+        "cyp1a2_veith": "bool",
+        "cyp2c9_veith": "bool",
+        "cyp2c9_substrate_carbonmangels": "bool",
+        "cyp2d6_substrate_carbonmangels": "bool",
+        "cyp3a4_substrate_carbonmangels": "bool",
+        "bbb_martins": "bool",
+        "ppbr_az": "seq",
+        "half_life_obach": "seq",
+        "clearance_hepatocyte_az": "seq",
+        "clearance_microsome_az": "seq",
+        "tox21-NR-AR": "bool",
+        "tox21-NR-AR-LBD": "bool",
+        "tox21-NR-AhR": "bool",
+        "tox21-NR-Aromatase": "bool",
+        "tox21-NR-ER": "bool",
+        "tox21-NR-ER-LBD": "bool",
+        "tox21-NR-PPAR-gamma": "bool",
+        "tox21-SR-ARE": "bool",
+        "tox21-SR-ATAD5": "bool",
+        "tox21-SR-HSE": "bool",
+        "tox21-SR-MMP": "bool",
+        "tox21-SR-p53": "bool",
+        "toxcast-ACEA_T47D_80hr_Negative": "bool",
+        "toxcast-ACEA_T47D_80hr_Positive": "bool",
+        "toxcast-APR_HepG2_CellCycleArrest_24h_dn": "bool",
+        "toxcast-APR_HepG2_CellCycleArrest_24h_up": "bool",
+        "toxcast-APR_HepG2_CellCycleArrest_72h_dn": "bool",
+        "toxcast-APR_HepG2_CellLoss_24h_dn": "bool",
+        "toxcast-APR_HepG2_CellLoss_72h_dn": "bool",
+        "toxcast-APR_HepG2_MicrotubuleCSK_24h_dn": "bool",
+        "toxcast-APR_HepG2_MicrotubuleCSK_24h_up": "bool",
+        "toxcast-APR_HepG2_MicrotubuleCSK_72h_dn": "bool",
+        "toxcast-APR_HepG2_MicrotubuleCSK_72h_up": "bool",
+        "toxcast-APR_HepG2_MitoMass_24h_dn": "bool",
+        "toxcast-APR_HepG2_MitoMass_24h_up": "bool",
+        "toxcast-APR_HepG2_MitoMass_72h_dn": "bool",
+        "toxcast-APR_HepG2_MitoMass_72h_up": "bool",
+        "toxcast-APR_HepG2_MitoMembPot_1h_dn": "bool",
+        "toxcast-APR_HepG2_MitoMembPot_24h_dn": "bool",
+        "toxcast-APR_HepG2_MitoMembPot_72h_dn": "bool",
+        "toxcast-APR_HepG2_MitoticArrest_24h_up": "bool",
+        "toxcast-APR_HepG2_MitoticArrest_72h_up": "bool",
+        "toxcast-APR_HepG2_NuclearSize_24h_dn": "bool",
+        "toxcast-APR_HepG2_NuclearSize_72h_dn": "bool",
+        "toxcast-APR_HepG2_NuclearSize_72h_up": "bool",
+        "toxcast-APR_HepG2_OxidativeStress_24h_up": "bool",
+        "toxcast-APR_HepG2_OxidativeStress_72h_up": "bool",
+        "toxcast-APR_HepG2_StressKinase_1h_up": "bool",
+        "toxcast-APR_HepG2_StressKinase_24h_up": "bool",
+        "toxcast-APR_HepG2_StressKinase_72h_up": "bool",
+        "toxcast-APR_HepG2_p53Act_24h_up": "bool",
+        "toxcast-APR_HepG2_p53Act_72h_up": "bool",
+        "toxcast-APR_Hepat_Apoptosis_24hr_up": "bool",
+        "toxcast-APR_Hepat_Apoptosis_48hr_up": "bool",
+        "toxcast-APR_Hepat_CellLoss_24hr_dn": "bool",
+        "toxcast-APR_Hepat_CellLoss_48hr_dn": "bool",
+        "toxcast-APR_Hepat_DNADamage_24hr_up": "bool",
+        "toxcast-APR_Hepat_DNADamage_48hr_up": "bool",
+        "toxcast-APR_Hepat_DNATexture_24hr_up": "bool",
+        "toxcast-APR_Hepat_DNATexture_48hr_up": "bool",
+        "toxcast-APR_Hepat_MitoFxnI_1hr_dn": "bool",
+        "toxcast-APR_Hepat_MitoFxnI_24hr_dn": "bool",
+        "toxcast-APR_Hepat_MitoFxnI_48hr_dn": "bool",
+        "toxcast-APR_Hepat_NuclearSize_24hr_dn": "bool",
+        "toxcast-APR_Hepat_NuclearSize_48hr_dn": "bool",
+        "toxcast-APR_Hepat_Steatosis_24hr_up": "bool",
+        "toxcast-APR_Hepat_Steatosis_48hr_up": "bool",
+        "toxcast-ATG_AP_1_CIS_dn": "bool",
+        "toxcast-ATG_AP_1_CIS_up": "bool",
+        "toxcast-ATG_AP_2_CIS_dn": "bool",
+        "toxcast-ATG_AP_2_CIS_up": "bool",
+        "toxcast-ATG_AR_TRANS_dn": "bool",
+        "toxcast-ATG_AR_TRANS_up": "bool",
+        "toxcast-ATG_Ahr_CIS_dn": "bool",
+        "toxcast-ATG_Ahr_CIS_up": "bool",
+        "toxcast-ATG_BRE_CIS_dn": "bool",
+        "toxcast-ATG_BRE_CIS_up": "bool",
+        "toxcast-ATG_CAR_TRANS_dn": "bool",
+        "toxcast-ATG_CAR_TRANS_up": "bool",
+        "toxcast-ATG_CMV_CIS_dn": "bool",
+        "toxcast-ATG_CMV_CIS_up": "bool",
+        "toxcast-ATG_CRE_CIS_dn": "bool",
+        "toxcast-ATG_CRE_CIS_up": "bool",
+        "toxcast-ATG_C_EBP_CIS_dn": "bool",
+        "toxcast-ATG_C_EBP_CIS_up": "bool",
+        "toxcast-ATG_DR4_LXR_CIS_dn": "bool",
+        "toxcast-ATG_DR4_LXR_CIS_up": "bool",
+        "toxcast-ATG_DR5_CIS_dn": "bool",
+        "toxcast-ATG_DR5_CIS_up": "bool",
+        "toxcast-ATG_E2F_CIS_dn": "bool",
+        "toxcast-ATG_E2F_CIS_up": "bool",
+        "toxcast-ATG_EGR_CIS_up": "bool",
+        "toxcast-ATG_ERE_CIS_dn": "bool",
+        "toxcast-ATG_ERE_CIS_up": "bool",
+        "toxcast-ATG_ERRa_TRANS_dn": "bool",
+        "toxcast-ATG_ERRg_TRANS_dn": "bool",
+        "toxcast-ATG_ERRg_TRANS_up": "bool",
+        "toxcast-ATG_ERa_TRANS_up": "bool",
+        "toxcast-ATG_E_Box_CIS_dn": "bool",
+        "toxcast-ATG_E_Box_CIS_up": "bool",
+        "toxcast-ATG_Ets_CIS_dn": "bool",
+        "toxcast-ATG_Ets_CIS_up": "bool",
+        "toxcast-ATG_FXR_TRANS_up": "bool",
+        "toxcast-ATG_FoxA2_CIS_dn": "bool",
+        "toxcast-ATG_FoxA2_CIS_up": "bool",
+        "toxcast-ATG_FoxO_CIS_dn": "bool",
+        "toxcast-ATG_FoxO_CIS_up": "bool",
+        "toxcast-ATG_GAL4_TRANS_dn": "bool",
+        "toxcast-ATG_GATA_CIS_dn": "bool",
+        "toxcast-ATG_GATA_CIS_up": "bool",
+        "toxcast-ATG_GLI_CIS_dn": "bool",
+        "toxcast-ATG_GLI_CIS_up": "bool",
+        "toxcast-ATG_GRE_CIS_dn": "bool",
+        "toxcast-ATG_GRE_CIS_up": "bool",
+        "toxcast-ATG_GR_TRANS_dn": "bool",
+        "toxcast-ATG_GR_TRANS_up": "bool",
+        "toxcast-ATG_HIF1a_CIS_dn": "bool",
+        "toxcast-ATG_HIF1a_CIS_up": "bool",
+        "toxcast-ATG_HNF4a_TRANS_dn": "bool",
+        "toxcast-ATG_HNF4a_TRANS_up": "bool",
+        "toxcast-ATG_HNF6_CIS_dn": "bool",
+        "toxcast-ATG_HNF6_CIS_up": "bool",
+        "toxcast-ATG_HSE_CIS_dn": "bool",
+        "toxcast-ATG_HSE_CIS_up": "bool",
+        "toxcast-ATG_IR1_CIS_dn": "bool",
+        "toxcast-ATG_IR1_CIS_up": "bool",
+        "toxcast-ATG_ISRE_CIS_dn": "bool",
+        "toxcast-ATG_ISRE_CIS_up": "bool",
+        "toxcast-ATG_LXRa_TRANS_dn": "bool",
+        "toxcast-ATG_LXRa_TRANS_up": "bool",
+        "toxcast-ATG_LXRb_TRANS_dn": "bool",
+        "toxcast-ATG_LXRb_TRANS_up": "bool",
+        "toxcast-ATG_MRE_CIS_up": "bool",
+        "toxcast-ATG_M_06_TRANS_up": "bool",
+        "toxcast-ATG_M_19_CIS_dn": "bool",
+        "toxcast-ATG_M_19_TRANS_dn": "bool",
+        "toxcast-ATG_M_19_TRANS_up": "bool",
+        "toxcast-ATG_M_32_CIS_dn": "bool",
+        "toxcast-ATG_M_32_CIS_up": "bool",
+        "toxcast-ATG_M_32_TRANS_dn": "bool",
+        "toxcast-ATG_M_32_TRANS_up": "bool",
+        "toxcast-ATG_M_61_TRANS_up": "bool",
+        "toxcast-ATG_Myb_CIS_dn": "bool",
+        "toxcast-ATG_Myb_CIS_up": "bool",
+        "toxcast-ATG_Myc_CIS_dn": "bool",
+        "toxcast-ATG_Myc_CIS_up": "bool",
+        "toxcast-ATG_NFI_CIS_dn": "bool",
+        "toxcast-ATG_NFI_CIS_up": "bool",
+        "toxcast-ATG_NF_kB_CIS_dn": "bool",
+        "toxcast-ATG_NF_kB_CIS_up": "bool",
+        "toxcast-ATG_NRF1_CIS_dn": "bool",
+        "toxcast-ATG_NRF1_CIS_up": "bool",
+        "toxcast-ATG_NRF2_ARE_CIS_dn": "bool",
+        "toxcast-ATG_NRF2_ARE_CIS_up": "bool",
+        "toxcast-ATG_NURR1_TRANS_dn": "bool",
+        "toxcast-ATG_NURR1_TRANS_up": "bool",
+        "toxcast-ATG_Oct_MLP_CIS_dn": "bool",
+        "toxcast-ATG_Oct_MLP_CIS_up": "bool",
+        "toxcast-ATG_PBREM_CIS_dn": "bool",
+        "toxcast-ATG_PBREM_CIS_up": "bool",
+        "toxcast-ATG_PPARa_TRANS_dn": "bool",
+        "toxcast-ATG_PPARa_TRANS_up": "bool",
+        "toxcast-ATG_PPARd_TRANS_up": "bool",
+        "toxcast-ATG_PPARg_TRANS_up": "bool",
+        "toxcast-ATG_PPRE_CIS_dn": "bool",
+        "toxcast-ATG_PPRE_CIS_up": "bool",
+        "toxcast-ATG_PXRE_CIS_dn": "bool",
+        "toxcast-ATG_PXRE_CIS_up": "bool",
+        "toxcast-ATG_PXR_TRANS_dn": "bool",
+        "toxcast-ATG_PXR_TRANS_up": "bool",
+        "toxcast-ATG_Pax6_CIS_up": "bool",
+        "toxcast-ATG_RARa_TRANS_dn": "bool",
+        "toxcast-ATG_RARa_TRANS_up": "bool",
+        "toxcast-ATG_RARb_TRANS_dn": "bool",
+        "toxcast-ATG_RARb_TRANS_up": "bool",
+        "toxcast-ATG_RARg_TRANS_dn": "bool",
+        "toxcast-ATG_RARg_TRANS_up": "bool",
+        "toxcast-ATG_RORE_CIS_dn": "bool",
+        "toxcast-ATG_RORE_CIS_up": "bool",
+        "toxcast-ATG_RORb_TRANS_dn": "bool",
+        "toxcast-ATG_RORg_TRANS_dn": "bool",
+        "toxcast-ATG_RORg_TRANS_up": "bool",
+        "toxcast-ATG_RXRa_TRANS_dn": "bool",
+        "toxcast-ATG_RXRa_TRANS_up": "bool",
+        "toxcast-ATG_RXRb_TRANS_dn": "bool",
+        "toxcast-ATG_RXRb_TRANS_up": "bool",
+        "toxcast-ATG_SREBP_CIS_dn": "bool",
+        "toxcast-ATG_SREBP_CIS_up": "bool",
+        "toxcast-ATG_STAT3_CIS_dn": "bool",
+        "toxcast-ATG_STAT3_CIS_up": "bool",
+        "toxcast-ATG_Sox_CIS_dn": "bool",
+        "toxcast-ATG_Sox_CIS_up": "bool",
+        "toxcast-ATG_Sp1_CIS_dn": "bool",
+        "toxcast-ATG_Sp1_CIS_up": "bool",
+        "toxcast-ATG_TAL_CIS_dn": "bool",
+        "toxcast-ATG_TAL_CIS_up": "bool",
+        "toxcast-ATG_TA_CIS_dn": "bool",
+        "toxcast-ATG_TA_CIS_up": "bool",
+        "toxcast-ATG_TCF_b_cat_CIS_dn": "bool",
+        "toxcast-ATG_TCF_b_cat_CIS_up": "bool",
+        "toxcast-ATG_TGFb_CIS_dn": "bool",
+        "toxcast-ATG_TGFb_CIS_up": "bool",
+        "toxcast-ATG_THRa1_TRANS_dn": "bool",
+        "toxcast-ATG_THRa1_TRANS_up": "bool",
+        "toxcast-ATG_VDRE_CIS_dn": "bool",
+        "toxcast-ATG_VDRE_CIS_up": "bool",
+        "toxcast-ATG_VDR_TRANS_dn": "bool",
+        "toxcast-ATG_VDR_TRANS_up": "bool",
+        "toxcast-ATG_XTT_Cytotoxicity_up": "bool",
+        "toxcast-ATG_Xbp1_CIS_dn": "bool",
+        "toxcast-ATG_Xbp1_CIS_up": "bool",
+        "toxcast-ATG_p53_CIS_dn": "bool",
+        "toxcast-ATG_p53_CIS_up": "bool",
+        "toxcast-BSK_3C_Eselectin_down": "bool",
+        "toxcast-BSK_3C_HLADR_down": "bool",
+        "toxcast-BSK_3C_ICAM1_down": "bool",
+        "toxcast-BSK_3C_IL8_down": "bool",
+        "toxcast-BSK_3C_MCP1_down": "bool",
+        "toxcast-BSK_3C_MIG_down": "bool",
+        "toxcast-BSK_3C_Proliferation_down": "bool",
+        "toxcast-BSK_3C_SRB_down": "bool",
+        "toxcast-BSK_3C_Thrombomodulin_down": "bool",
+        "toxcast-BSK_3C_Thrombomodulin_up": "bool",
+        "toxcast-BSK_3C_TissueFactor_down": "bool",
+        "toxcast-BSK_3C_TissueFactor_up": "bool",
+        "toxcast-BSK_3C_VCAM1_down": "bool",
+        "toxcast-BSK_3C_Vis_down": "bool",
+        "toxcast-BSK_3C_uPAR_down": "bool",
+        "toxcast-BSK_4H_Eotaxin3_down": "bool",
+        "toxcast-BSK_4H_MCP1_down": "bool",
+        "toxcast-BSK_4H_Pselectin_down": "bool",
+        "toxcast-BSK_4H_Pselectin_up": "bool",
+        "toxcast-BSK_4H_SRB_down": "bool",
+        "toxcast-BSK_4H_VCAM1_down": "bool",
+        "toxcast-BSK_4H_VEGFRII_down": "bool",
+        "toxcast-BSK_4H_uPAR_down": "bool",
+        "toxcast-BSK_4H_uPAR_up": "bool",
+        "toxcast-BSK_BE3C_HLADR_down": "bool",
+        "toxcast-BSK_BE3C_IL1a_down": "bool",
+        "toxcast-BSK_BE3C_IP10_down": "bool",
+        "toxcast-BSK_BE3C_MIG_down": "bool",
+        "toxcast-BSK_BE3C_MMP1_down": "bool",
+        "toxcast-BSK_BE3C_MMP1_up": "bool",
+        "toxcast-BSK_BE3C_PAI1_down": "bool",
+        "toxcast-BSK_BE3C_SRB_down": "bool",
+        "toxcast-BSK_BE3C_TGFb1_down": "bool",
+        "toxcast-BSK_BE3C_tPA_down": "bool",
+        "toxcast-BSK_BE3C_uPAR_down": "bool",
+        "toxcast-BSK_BE3C_uPAR_up": "bool",
+        "toxcast-BSK_BE3C_uPA_down": "bool",
+        "toxcast-BSK_CASM3C_HLADR_down": "bool",
+        "toxcast-BSK_CASM3C_IL6_down": "bool",
+        "toxcast-BSK_CASM3C_IL6_up": "bool",
+        "toxcast-BSK_CASM3C_IL8_down": "bool",
+        "toxcast-BSK_CASM3C_LDLR_down": "bool",
+        "toxcast-BSK_CASM3C_LDLR_up": "bool",
+        "toxcast-BSK_CASM3C_MCP1_down": "bool",
+        "toxcast-BSK_CASM3C_MCP1_up": "bool",
+        "toxcast-BSK_CASM3C_MCSF_down": "bool",
+        "toxcast-BSK_CASM3C_MCSF_up": "bool",
+        "toxcast-BSK_CASM3C_MIG_down": "bool",
+        "toxcast-BSK_CASM3C_Proliferation_down": "bool",
+        "toxcast-BSK_CASM3C_Proliferation_up": "bool",
+        "toxcast-BSK_CASM3C_SAA_down": "bool",
+        "toxcast-BSK_CASM3C_SAA_up": "bool",
+        "toxcast-BSK_CASM3C_SRB_down": "bool",
+        "toxcast-BSK_CASM3C_Thrombomodulin_down": "bool",
+        "toxcast-BSK_CASM3C_Thrombomodulin_up": "bool",
+        "toxcast-BSK_CASM3C_TissueFactor_down": "bool",
+        "toxcast-BSK_CASM3C_VCAM1_down": "bool",
+        "toxcast-BSK_CASM3C_VCAM1_up": "bool",
+        "toxcast-BSK_CASM3C_uPAR_down": "bool",
+        "toxcast-BSK_CASM3C_uPAR_up": "bool",
+        "toxcast-BSK_KF3CT_ICAM1_down": "bool",
+        "toxcast-BSK_KF3CT_IL1a_down": "bool",
+        "toxcast-BSK_KF3CT_IP10_down": "bool",
+        "toxcast-BSK_KF3CT_IP10_up": "bool",
+        "toxcast-BSK_KF3CT_MCP1_down": "bool",
+        "toxcast-BSK_KF3CT_MCP1_up": "bool",
+        "toxcast-BSK_KF3CT_MMP9_down": "bool",
+        "toxcast-BSK_KF3CT_SRB_down": "bool",
+        "toxcast-BSK_KF3CT_TGFb1_down": "bool",
+        "toxcast-BSK_KF3CT_TIMP2_down": "bool",
+        "toxcast-BSK_KF3CT_uPA_down": "bool",
+        "toxcast-BSK_LPS_CD40_down": "bool",
+        "toxcast-BSK_LPS_Eselectin_down": "bool",
+        "toxcast-BSK_LPS_Eselectin_up": "bool",
+        "toxcast-BSK_LPS_IL1a_down": "bool",
+        "toxcast-BSK_LPS_IL1a_up": "bool",
+        "toxcast-BSK_LPS_IL8_down": "bool",
+        "toxcast-BSK_LPS_IL8_up": "bool",
+        "toxcast-BSK_LPS_MCP1_down": "bool",
+        "toxcast-BSK_LPS_MCSF_down": "bool",
+        "toxcast-BSK_LPS_PGE2_down": "bool",
+        "toxcast-BSK_LPS_PGE2_up": "bool",
+        "toxcast-BSK_LPS_SRB_down": "bool",
+        "toxcast-BSK_LPS_TNFa_down": "bool",
+        "toxcast-BSK_LPS_TNFa_up": "bool",
+        "toxcast-BSK_LPS_TissueFactor_down": "bool",
+        "toxcast-BSK_LPS_TissueFactor_up": "bool",
+        "toxcast-BSK_LPS_VCAM1_down": "bool",
+        "toxcast-BSK_SAg_CD38_down": "bool",
+        "toxcast-BSK_SAg_CD40_down": "bool",
+        "toxcast-BSK_SAg_CD69_down": "bool",
+        "toxcast-BSK_SAg_Eselectin_down": "bool",
+        "toxcast-BSK_SAg_Eselectin_up": "bool",
+        "toxcast-BSK_SAg_IL8_down": "bool",
+        "toxcast-BSK_SAg_IL8_up": "bool",
+        "toxcast-BSK_SAg_MCP1_down": "bool",
+        "toxcast-BSK_SAg_MIG_down": "bool",
+        "toxcast-BSK_SAg_PBMCCytotoxicity_down": "bool",
+        "toxcast-BSK_SAg_PBMCCytotoxicity_up": "bool",
+        "toxcast-BSK_SAg_Proliferation_down": "bool",
+        "toxcast-BSK_SAg_SRB_down": "bool",
+        "toxcast-BSK_hDFCGF_CollagenIII_down": "bool",
+        "toxcast-BSK_hDFCGF_EGFR_down": "bool",
+        "toxcast-BSK_hDFCGF_EGFR_up": "bool",
+        "toxcast-BSK_hDFCGF_IL8_down": "bool",
+        "toxcast-BSK_hDFCGF_IP10_down": "bool",
+        "toxcast-BSK_hDFCGF_MCSF_down": "bool",
+        "toxcast-BSK_hDFCGF_MIG_down": "bool",
+        "toxcast-BSK_hDFCGF_MMP1_down": "bool",
+        "toxcast-BSK_hDFCGF_MMP1_up": "bool",
+        "toxcast-BSK_hDFCGF_PAI1_down": "bool",
+        "toxcast-BSK_hDFCGF_Proliferation_down": "bool",
+        "toxcast-BSK_hDFCGF_SRB_down": "bool",
+        "toxcast-BSK_hDFCGF_TIMP1_down": "bool",
+        "toxcast-BSK_hDFCGF_VCAM1_down": "bool",
+        "toxcast-CEETOX_H295R_11DCORT_dn": "bool",
+        "toxcast-CEETOX_H295R_ANDR_dn": "bool",
+        "toxcast-CEETOX_H295R_CORTISOL_dn": "bool",
+        "toxcast-CEETOX_H295R_DOC_dn": "bool",
+        "toxcast-CEETOX_H295R_DOC_up": "bool",
+        "toxcast-CEETOX_H295R_ESTRADIOL_dn": "bool",
+        "toxcast-CEETOX_H295R_ESTRADIOL_up": "bool",
+        "toxcast-CEETOX_H295R_ESTRONE_dn": "bool",
+        "toxcast-CEETOX_H295R_ESTRONE_up": "bool",
+        "toxcast-CEETOX_H295R_OHPREG_up": "bool",
+        "toxcast-CEETOX_H295R_OHPROG_dn": "bool",
+        "toxcast-CEETOX_H295R_OHPROG_up": "bool",
+        "toxcast-CEETOX_H295R_PROG_up": "bool",
+        "toxcast-CEETOX_H295R_TESTO_dn": "bool",
+        "toxcast-CLD_ABCB1_48hr": "bool",
+        "toxcast-CLD_ABCG2_48hr": "bool",
+        "toxcast-CLD_CYP1A1_24hr": "bool",
+        "toxcast-CLD_CYP1A1_48hr": "bool",
+        "toxcast-CLD_CYP1A1_6hr": "bool",
+        "toxcast-CLD_CYP1A2_24hr": "bool",
+        "toxcast-CLD_CYP1A2_48hr": "bool",
+        "toxcast-CLD_CYP1A2_6hr": "bool",
+        "toxcast-CLD_CYP2B6_24hr": "bool",
+        "toxcast-CLD_CYP2B6_48hr": "bool",
+        "toxcast-CLD_CYP2B6_6hr": "bool",
+        "toxcast-CLD_CYP3A4_24hr": "bool",
+        "toxcast-CLD_CYP3A4_48hr": "bool",
+        "toxcast-CLD_CYP3A4_6hr": "bool",
+        "toxcast-CLD_GSTA2_48hr": "bool",
+        "toxcast-CLD_SULT2A_24hr": "bool",
+        "toxcast-CLD_SULT2A_48hr": "bool",
+        "toxcast-CLD_UGT1A1_24hr": "bool",
+        "toxcast-CLD_UGT1A1_48hr": "bool",
+        "toxcast-NCCT_HEK293T_CellTiterGLO": "bool",
+        "toxcast-NCCT_QuantiLum_inhib_2_dn": "bool",
+        "toxcast-NCCT_QuantiLum_inhib_dn": "bool",
+        "toxcast-NCCT_TPO_AUR_dn": "bool",
+        "toxcast-NCCT_TPO_GUA_dn": "bool",
+        "toxcast-NHEERL_ZF_144hpf_TERATOSCORE_up": "bool",
+        "toxcast-NVS_ADME_hCYP19A1": "bool",
+        "toxcast-NVS_ADME_hCYP1A1": "bool",
+        "toxcast-NVS_ADME_hCYP1A2": "bool",
+        "toxcast-NVS_ADME_hCYP2A6": "bool",
+        "toxcast-NVS_ADME_hCYP2B6": "bool",
+        "toxcast-NVS_ADME_hCYP2C19": "bool",
+        "toxcast-NVS_ADME_hCYP2C9": "bool",
+        "toxcast-NVS_ADME_hCYP2D6": "bool",
+        "toxcast-NVS_ADME_hCYP3A4": "bool",
+        "toxcast-NVS_ADME_hCYP4F12": "bool",
+        "toxcast-NVS_ADME_rCYP2C12": "bool",
+        "toxcast-NVS_ENZ_hAChE": "bool",
+        "toxcast-NVS_ENZ_hAMPKa1": "bool",
+        "toxcast-NVS_ENZ_hAurA": "bool",
+        "toxcast-NVS_ENZ_hBACE": "bool",
+        "toxcast-NVS_ENZ_hCASP5": "bool",
+        "toxcast-NVS_ENZ_hCK1D": "bool",
+        "toxcast-NVS_ENZ_hDUSP3": "bool",
+        "toxcast-NVS_ENZ_hES": "bool",
+        "toxcast-NVS_ENZ_hElastase": "bool",
+        "toxcast-NVS_ENZ_hFGFR1": "bool",
+        "toxcast-NVS_ENZ_hGSK3b": "bool",
+        "toxcast-NVS_ENZ_hMMP1": "bool",
+        "toxcast-NVS_ENZ_hMMP13": "bool",
+        "toxcast-NVS_ENZ_hMMP2": "bool",
+        "toxcast-NVS_ENZ_hMMP3": "bool",
+        "toxcast-NVS_ENZ_hMMP7": "bool",
+        "toxcast-NVS_ENZ_hMMP9": "bool",
+        "toxcast-NVS_ENZ_hPDE10": "bool",
+        "toxcast-NVS_ENZ_hPDE4A1": "bool",
+        "toxcast-NVS_ENZ_hPDE5": "bool",
+        "toxcast-NVS_ENZ_hPI3Ka": "bool",
+        "toxcast-NVS_ENZ_hPTEN": "bool",
+        "toxcast-NVS_ENZ_hPTPN11": "bool",
+        "toxcast-NVS_ENZ_hPTPN12": "bool",
+        "toxcast-NVS_ENZ_hPTPN13": "bool",
+        "toxcast-NVS_ENZ_hPTPN9": "bool",
+        "toxcast-NVS_ENZ_hPTPRC": "bool",
+        "toxcast-NVS_ENZ_hSIRT1": "bool",
+        "toxcast-NVS_ENZ_hSIRT2": "bool",
+        "toxcast-NVS_ENZ_hTrkA": "bool",
+        "toxcast-NVS_ENZ_hVEGFR2": "bool",
+        "toxcast-NVS_ENZ_oCOX1": "bool",
+        "toxcast-NVS_ENZ_oCOX2": "bool",
+        "toxcast-NVS_ENZ_rAChE": "bool",
+        "toxcast-NVS_ENZ_rCNOS": "bool",
+        "toxcast-NVS_ENZ_rMAOAC": "bool",
+        "toxcast-NVS_ENZ_rMAOAP": "bool",
+        "toxcast-NVS_ENZ_rMAOBC": "bool",
+        "toxcast-NVS_ENZ_rMAOBP": "bool",
+        "toxcast-NVS_ENZ_rabI2C": "bool",
+        "toxcast-NVS_GPCR_bAdoR_NonSelective": "bool",
+        "toxcast-NVS_GPCR_bDR_NonSelective": "bool",
+        "toxcast-NVS_GPCR_g5HT4": "bool",
+        "toxcast-NVS_GPCR_gH2": "bool",
+        "toxcast-NVS_GPCR_gLTB4": "bool",
+        "toxcast-NVS_GPCR_gLTD4": "bool",
+        "toxcast-NVS_GPCR_gMPeripheral_NonSelective": "bool",
+        "toxcast-NVS_GPCR_gOpiateK": "bool",
+        "toxcast-NVS_GPCR_h5HT2A": "bool",
+        "toxcast-NVS_GPCR_h5HT5A": "bool",
+        "toxcast-NVS_GPCR_h5HT6": "bool",
+        "toxcast-NVS_GPCR_h5HT7": "bool",
+        "toxcast-NVS_GPCR_hAT1": "bool",
+        "toxcast-NVS_GPCR_hAdoRA1": "bool",
+        "toxcast-NVS_GPCR_hAdoRA2a": "bool",
+        "toxcast-NVS_GPCR_hAdra2A": "bool",
+        "toxcast-NVS_GPCR_hAdra2C": "bool",
+        "toxcast-NVS_GPCR_hAdrb1": "bool",
+        "toxcast-NVS_GPCR_hAdrb2": "bool",
+        "toxcast-NVS_GPCR_hAdrb3": "bool",
+        "toxcast-NVS_GPCR_hDRD1": "bool",
+        "toxcast-NVS_GPCR_hDRD2s": "bool",
+        "toxcast-NVS_GPCR_hDRD4.4": "bool",
+        "toxcast-NVS_GPCR_hH1": "bool",
+        "toxcast-NVS_GPCR_hLTB4_BLT1": "bool",
+        "toxcast-NVS_GPCR_hM1": "bool",
+        "toxcast-NVS_GPCR_hM2": "bool",
+        "toxcast-NVS_GPCR_hM3": "bool",
+        "toxcast-NVS_GPCR_hM4": "bool",
+        "toxcast-NVS_GPCR_hNK2": "bool",
+        "toxcast-NVS_GPCR_hOpiate_D1": "bool",
+        "toxcast-NVS_GPCR_hOpiate_mu": "bool",
+        "toxcast-NVS_GPCR_hTXA2": "bool",
+        "toxcast-NVS_GPCR_p5HT2C": "bool",
+        "toxcast-NVS_GPCR_r5HT1_NonSelective": "bool",
+        "toxcast-NVS_GPCR_r5HT_NonSelective": "bool",
+        "toxcast-NVS_GPCR_rAdra1B": "bool",
+        "toxcast-NVS_GPCR_rAdra1_NonSelective": "bool",
+        "toxcast-NVS_GPCR_rAdra2_NonSelective": "bool",
+        "toxcast-NVS_GPCR_rAdrb_NonSelective": "bool",
+        "toxcast-NVS_GPCR_rNK1": "bool",
+        "toxcast-NVS_GPCR_rNK3": "bool",
+        "toxcast-NVS_GPCR_rOpiate_NonSelective": "bool",
+        "toxcast-NVS_GPCR_rOpiate_NonSelectiveNa": "bool",
+        "toxcast-NVS_GPCR_rSST": "bool",
+        "toxcast-NVS_GPCR_rTRH": "bool",
+        "toxcast-NVS_GPCR_rV1": "bool",
+        "toxcast-NVS_GPCR_rabPAF": "bool",
+        "toxcast-NVS_GPCR_rmAdra2B": "bool",
+        "toxcast-NVS_IC_hKhERGCh": "bool",
+        "toxcast-NVS_IC_rCaBTZCHL": "bool",
+        "toxcast-NVS_IC_rCaDHPRCh_L": "bool",
+        "toxcast-NVS_IC_rNaCh_site2": "bool",
+        "toxcast-NVS_LGIC_bGABARa1": "bool",
+        "toxcast-NVS_LGIC_h5HT3": "bool",
+        "toxcast-NVS_LGIC_hNNR_NBungSens": "bool",
+        "toxcast-NVS_LGIC_rGABAR_NonSelective": "bool",
+        "toxcast-NVS_LGIC_rNNR_BungSens": "bool",
+        "toxcast-NVS_MP_hPBR": "bool",
+        "toxcast-NVS_MP_rPBR": "bool",
+        "toxcast-NVS_NR_bER": "bool",
+        "toxcast-NVS_NR_bPR": "bool",
+        "toxcast-NVS_NR_cAR": "bool",
+        "toxcast-NVS_NR_hAR": "bool",
+        "toxcast-NVS_NR_hCAR_Antagonist": "bool",
+        "toxcast-NVS_NR_hER": "bool",
+        "toxcast-NVS_NR_hFXR_Agonist": "bool",
+        "toxcast-NVS_NR_hFXR_Antagonist": "bool",
+        "toxcast-NVS_NR_hGR": "bool",
+        "toxcast-NVS_NR_hPPARa": "bool",
+        "toxcast-NVS_NR_hPPARg": "bool",
+        "toxcast-NVS_NR_hPR": "bool",
+        "toxcast-NVS_NR_hPXR": "bool",
+        "toxcast-NVS_NR_hRAR_Antagonist": "bool",
+        "toxcast-NVS_NR_hRARa_Agonist": "bool",
+        "toxcast-NVS_NR_hTRa_Antagonist": "bool",
+        "toxcast-NVS_NR_mERa": "bool",
+        "toxcast-NVS_NR_rAR": "bool",
+        "toxcast-NVS_NR_rMR": "bool",
+        "toxcast-NVS_OR_gSIGMA_NonSelective": "bool",
+        "toxcast-NVS_TR_gDAT": "bool",
+        "toxcast-NVS_TR_hAdoT": "bool",
+        "toxcast-NVS_TR_hDAT": "bool",
+        "toxcast-NVS_TR_hNET": "bool",
+        "toxcast-NVS_TR_hSERT": "bool",
+        "toxcast-NVS_TR_rNET": "bool",
+        "toxcast-NVS_TR_rSERT": "bool",
+        "toxcast-NVS_TR_rVMAT2": "bool",
+        "toxcast-OT_AR_ARELUC_AG_1440": "bool",
+        "toxcast-OT_AR_ARSRC1_0480": "bool",
+        "toxcast-OT_AR_ARSRC1_0960": "bool",
+        "toxcast-OT_ER_ERaERa_0480": "bool",
+        "toxcast-OT_ER_ERaERa_1440": "bool",
+        "toxcast-OT_ER_ERaERb_0480": "bool",
+        "toxcast-OT_ER_ERaERb_1440": "bool",
+        "toxcast-OT_ER_ERbERb_0480": "bool",
+        "toxcast-OT_ER_ERbERb_1440": "bool",
+        "toxcast-OT_ERa_EREGFP_0120": "bool",
+        "toxcast-OT_ERa_EREGFP_0480": "bool",
+        "toxcast-OT_FXR_FXRSRC1_0480": "bool",
+        "toxcast-OT_FXR_FXRSRC1_1440": "bool",
+        "toxcast-OT_NURR1_NURR1RXRa_0480": "bool",
+        "toxcast-OT_NURR1_NURR1RXRa_1440": "bool",
+        "toxcast-TOX21_ARE_BLA_Agonist_ch1": "bool",
+        "toxcast-TOX21_ARE_BLA_Agonist_ch2": "bool",
+        "toxcast-TOX21_ARE_BLA_agonist_ratio": "bool",
+        "toxcast-TOX21_ARE_BLA_agonist_viability": "bool",
+        "toxcast-TOX21_AR_BLA_Agonist_ch1": "bool",
+        "toxcast-TOX21_AR_BLA_Agonist_ch2": "bool",
+        "toxcast-TOX21_AR_BLA_Agonist_ratio": "bool",
+        "toxcast-TOX21_AR_BLA_Antagonist_ch1": "bool",
+        "toxcast-TOX21_AR_BLA_Antagonist_ch2": "bool",
+        "toxcast-TOX21_AR_BLA_Antagonist_ratio": "bool",
+        "toxcast-TOX21_AR_BLA_Antagonist_viability": "bool",
+        "toxcast-TOX21_AR_LUC_MDAKB2_Agonist": "bool",
+        "toxcast-TOX21_AR_LUC_MDAKB2_Antagonist": "bool",
+        "toxcast-TOX21_AR_LUC_MDAKB2_Antagonist2": "bool",
+        "toxcast-TOX21_AhR_LUC_Agonist": "bool",
+        "toxcast-TOX21_Aromatase_Inhibition": "bool",
+        "toxcast-TOX21_AutoFluor_HEK293_Cell_blue": "bool",
+        "toxcast-TOX21_AutoFluor_HEK293_Media_blue": "bool",
+        "toxcast-TOX21_AutoFluor_HEPG2_Cell_blue": "bool",
+        "toxcast-TOX21_AutoFluor_HEPG2_Cell_green": "bool",
+        "toxcast-TOX21_AutoFluor_HEPG2_Media_blue": "bool",
+        "toxcast-TOX21_AutoFluor_HEPG2_Media_green": "bool",
+        "toxcast-TOX21_ELG1_LUC_Agonist": "bool",
+        "toxcast-TOX21_ERa_BLA_Agonist_ch1": "bool",
+        "toxcast-TOX21_ERa_BLA_Agonist_ch2": "bool",
+        "toxcast-TOX21_ERa_BLA_Agonist_ratio": "bool",
+        "toxcast-TOX21_ERa_BLA_Antagonist_ch1": "bool",
+        "toxcast-TOX21_ERa_BLA_Antagonist_ch2": "bool",
+        "toxcast-TOX21_ERa_BLA_Antagonist_ratio": "bool",
+        "toxcast-TOX21_ERa_BLA_Antagonist_viability": "bool",
+        "toxcast-TOX21_ERa_LUC_BG1_Agonist": "bool",
+        "toxcast-TOX21_ERa_LUC_BG1_Antagonist": "bool",
+        "toxcast-TOX21_ESRE_BLA_ch1": "bool",
+        "toxcast-TOX21_ESRE_BLA_ch2": "bool",
+        "toxcast-TOX21_ESRE_BLA_ratio": "bool",
+        "toxcast-TOX21_ESRE_BLA_viability": "bool",
+        "toxcast-TOX21_FXR_BLA_Antagonist_ch1": "bool",
+        "toxcast-TOX21_FXR_BLA_Antagonist_ch2": "bool",
+        "toxcast-TOX21_FXR_BLA_agonist_ch2": "bool",
+        "toxcast-TOX21_FXR_BLA_agonist_ratio": "bool",
+        "toxcast-TOX21_FXR_BLA_antagonist_ratio": "bool",
+        "toxcast-TOX21_FXR_BLA_antagonist_viability": "bool",
+        "toxcast-TOX21_GR_BLA_Agonist_ch1": "bool",
+        "toxcast-TOX21_GR_BLA_Agonist_ch2": "bool",
+        "toxcast-TOX21_GR_BLA_Agonist_ratio": "bool",
+        "toxcast-TOX21_GR_BLA_Antagonist_ch2": "bool",
+        "toxcast-TOX21_GR_BLA_Antagonist_ratio": "bool",
+        "toxcast-TOX21_GR_BLA_Antagonist_viability": "bool",
+        "toxcast-TOX21_HSE_BLA_agonist_ch1": "bool",
+        "toxcast-TOX21_HSE_BLA_agonist_ch2": "bool",
+        "toxcast-TOX21_HSE_BLA_agonist_ratio": "bool",
+        "toxcast-TOX21_HSE_BLA_agonist_viability": "bool",
+        "toxcast-TOX21_MMP_ratio_down": "bool",
+        "toxcast-TOX21_MMP_ratio_up": "bool",
+        "toxcast-TOX21_MMP_viability": "bool",
+        "toxcast-TOX21_NFkB_BLA_agonist_ch1": "bool",
+        "toxcast-TOX21_NFkB_BLA_agonist_ch2": "bool",
+        "toxcast-TOX21_NFkB_BLA_agonist_ratio": "bool",
+        "toxcast-TOX21_NFkB_BLA_agonist_viability": "bool",
+        "toxcast-TOX21_PPARd_BLA_Agonist_viability": "bool",
+        "toxcast-TOX21_PPARd_BLA_Antagonist_ch1": "bool",
+        "toxcast-TOX21_PPARd_BLA_agonist_ch1": "bool",
+        "toxcast-TOX21_PPARd_BLA_agonist_ch2": "bool",
+        "toxcast-TOX21_PPARd_BLA_agonist_ratio": "bool",
+        "toxcast-TOX21_PPARd_BLA_antagonist_ratio": "bool",
+        "toxcast-TOX21_PPARd_BLA_antagonist_viability": "bool",
+        "toxcast-TOX21_PPARg_BLA_Agonist_ch1": "bool",
+        "toxcast-TOX21_PPARg_BLA_Agonist_ch2": "bool",
+        "toxcast-TOX21_PPARg_BLA_Agonist_ratio": "bool",
+        "toxcast-TOX21_PPARg_BLA_Antagonist_ch1": "bool",
+        "toxcast-TOX21_PPARg_BLA_antagonist_ratio": "bool",
+        "toxcast-TOX21_PPARg_BLA_antagonist_viability": "bool",
+        "toxcast-TOX21_TR_LUC_GH3_Agonist": "bool",
+        "toxcast-TOX21_TR_LUC_GH3_Antagonist": "bool",
+        "toxcast-TOX21_VDR_BLA_Agonist_viability": "bool",
+        "toxcast-TOX21_VDR_BLA_Antagonist_ch1": "bool",
+        "toxcast-TOX21_VDR_BLA_agonist_ch2": "bool",
+        "toxcast-TOX21_VDR_BLA_agonist_ratio": "bool",
+        "toxcast-TOX21_VDR_BLA_antagonist_ratio": "bool",
+        "toxcast-TOX21_VDR_BLA_antagonist_viability": "bool",
+        "toxcast-TOX21_p53_BLA_p1_ch1": "bool",
+        "toxcast-TOX21_p53_BLA_p1_ch2": "bool",
+        "toxcast-TOX21_p53_BLA_p1_ratio": "bool",
+        "toxcast-TOX21_p53_BLA_p1_viability": "bool",
+        "toxcast-TOX21_p53_BLA_p2_ch1": "bool",
+        "toxcast-TOX21_p53_BLA_p2_ch2": "bool",
+        "toxcast-TOX21_p53_BLA_p2_ratio": "bool",
+        "toxcast-TOX21_p53_BLA_p2_viability": "bool",
+        "toxcast-TOX21_p53_BLA_p3_ch1": "bool",
+        "toxcast-TOX21_p53_BLA_p3_ch2": "bool",
+        "toxcast-TOX21_p53_BLA_p3_ratio": "bool",
+        "toxcast-TOX21_p53_BLA_p3_viability": "bool",
+        "toxcast-TOX21_p53_BLA_p4_ch1": "bool",
+        "toxcast-TOX21_p53_BLA_p4_ch2": "bool",
+        "toxcast-TOX21_p53_BLA_p4_ratio": "bool",
+        "toxcast-TOX21_p53_BLA_p4_viability": "bool",
+        "toxcast-TOX21_p53_BLA_p5_ch1": "bool",
+        "toxcast-TOX21_p53_BLA_p5_ch2": "bool",
+        "toxcast-TOX21_p53_BLA_p5_ratio": "bool",
+        "toxcast-TOX21_p53_BLA_p5_viability": "bool",
+        "toxcast-Tanguay_ZF_120hpf_AXIS_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_ActivityScore": "bool",
+        "toxcast-Tanguay_ZF_120hpf_BRAI_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_CFIN_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_CIRC_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_EYE_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_JAW_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_MORT_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_OTIC_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_PE_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_PFIN_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_PIG_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_SNOU_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_SOMI_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_SWIM_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_TRUN_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_TR_up": "bool",
+        "toxcast-Tanguay_ZF_120hpf_YSE_up": "bool",
+        "clintox": "bool",
+        "herg": "bool",
+        "herg_central-hERG_at_1uM": "seq",
+        "herg_central-hERG_at_10uM": "seq",
+        "herg_central-hERG_inhib": "bool",
+        "dili": "bool",
+        "skin_reaction": "bool",
+        "ames": "bool",
+        "carcinogens_lagunin": "bool",
+        "ld50_zhu": "seq"
+    }
+}