fix(ui): offer the SV modality; tests own the unsupported-modality refusal

fix(sv): read the frame claim out of `annotation`, and re-curate MSK

fix(sv): read MSK's hyphenated frame claim, in the classifier AND the depth gate

fix: close three silent-fallback wrong answers (modality, test floor, BYOD fusions)

feat(sv): structural-variant modality (ADR-0008) — fusions, with three gates

feat(panel): widen 19 → 29 genes (HR + MMR), and stop silently dropping uncurated genes

fix: empty-genes parity + name the reason in the mouse BYOD refusal

feat(api): expose samples_profiled so callers can reconstruct WT

feat(curate): add paad_cptac_2021 — the cohort the orchestrator join can align

merge: cohort survey + denominator fix into main (ADR-0006/0007)

cadence: re-curation policy for curated artifacts (ADR-0007)

cohorts: +2 curated (6 total); fix frequency denominators (TCGA KRAS 73%->91%)

C2: repost Broad CCLE terms in full (their continuity clause) + verify directly

deploy: attribution for the downloadable curated artifacts + fill the Space slug

C2: per-study commercial-use review — CCLE is restricted, not CC BY 4.0

C3: the +URL in the User-Agent is the contact channel — no email needed

C2 + C3: per-study license gate and polite client — source conditions complete

C4: curate-and-cache — the cBioPortal API leaves the request path

M3 deploy surface: gradio_ui.py + src/server.py

M3: BYOD upload + deploy hardening

M2: variant_by_subtype label-join + association test

M1: cBioPortal status-matrix curation + query_variant_status

scaffold: pdac-genomics-agent — third specialist for PDAC DNA (mutation/CNV) analysis