Update README.md
Browse files
README.md
CHANGED
|
@@ -17,7 +17,7 @@ Our current datasets include:
|
|
| 17 |
- **Drug list:** the **drugs** we consider for repurposing opportunities
|
| 18 |
- **Disease list:** the **diseases** we consider for repurposing opportunities
|
| 19 |
- **KG Nodes & Edges:** One of the methods we use to predict repurposing opportunities is based on knowledge graphs. We combine multiple upstream KGs and data sources to build an integrated KG. For a high level overview of the data, check our [data dashboard](https://data.dev.everycure.org/versions/latest/evidence). The nodes and edges of our integarted graph are available for download below.
|
| 20 |
-
- **
|
| 21 |
|
| 22 |
## Code & Documentation
|
| 23 |
|
|
@@ -36,7 +36,7 @@ Our current datasets include:
|
|
| 36 |
- **Lancet Haematology (2025)** β *Pioneering a new field of computational pharmacophenomics to unlock the life-saving potential of existing medicines.* Fajgenbaum DC et al. [everycure.org/lancet](https://everycure.org/lancet/)
|
| 37 |
- **Platform paper (preprint, 2025)** β *Every Cure's End-to-End AI-Enabled Drug Repurposing Platform: Integrating Human-in-the-Loop Expertise to Accelerate Impact.* [DOI: 10.58647/REXPO.25000098.v1](https://drugrepocentral.scienceopen.com/hosted-document?doi=10.58647/REXPO.25000098.v1)
|
| 38 |
- **MeDI (under submission)** β *MeDI: A Foundational Database to Support Drug Repurposing* β covers the MATRIX drug and disease list creation process.
|
| 39 |
-
- **Unmet Medical Need Index** β *Unmet Medical Need Index: A Large Language Model-based methodology to Quantify Unmet Medical Need across the Disease Landscape* β covers the methodology behind our Unmet Medical Need assessments.
|
| 40 |
|
| 41 |
## Programs
|
| 42 |
|
|
|
|
| 17 |
- **Drug list:** the **drugs** we consider for repurposing opportunities
|
| 18 |
- **Disease list:** the **diseases** we consider for repurposing opportunities
|
| 19 |
- **KG Nodes & Edges:** One of the methods we use to predict repurposing opportunities is based on knowledge graphs. We combine multiple upstream KGs and data sources to build an integrated KG. For a high level overview of the data, check our [data dashboard](https://data.dev.everycure.org/versions/latest/evidence). The nodes and edges of our integarted graph are available for download below.
|
| 20 |
+
- **matrix-scores:** the latest predictions for all drug-disease pairs from our KG-based method. These are updated approximately quarterly. A [heatmap application](https://prototypes.everycure.org/matrix-heatmap-public/) allows exploration of these scores. **Please note these scores indicate biological plausibility, not repurposing potential.**
|
| 21 |
|
| 22 |
## Code & Documentation
|
| 23 |
|
|
|
|
| 36 |
- **Lancet Haematology (2025)** β *Pioneering a new field of computational pharmacophenomics to unlock the life-saving potential of existing medicines.* Fajgenbaum DC et al. [everycure.org/lancet](https://everycure.org/lancet/)
|
| 37 |
- **Platform paper (preprint, 2025)** β *Every Cure's End-to-End AI-Enabled Drug Repurposing Platform: Integrating Human-in-the-Loop Expertise to Accelerate Impact.* [DOI: 10.58647/REXPO.25000098.v1](https://drugrepocentral.scienceopen.com/hosted-document?doi=10.58647/REXPO.25000098.v1)
|
| 38 |
- **MeDI (under submission)** β *MeDI: A Foundational Database to Support Drug Repurposing* β covers the MATRIX drug and disease list creation process.
|
| 39 |
+
- **Unmet Medical Need Index (PLOS Medicine, in review)** β *Unmet Medical Need Index: A Large Language Model-based methodology to Quantify Unmet Medical Need across the Disease Landscape* β covers the methodology behind our Unmet Medical Need assessments.
|
| 40 |
|
| 41 |
## Programs
|
| 42 |
|