README.md

---
title: GQuery AI - Biomedical Research Assistant
emoji: 🧬
colorFrom: blue
colorTo: purple
sdk: gradio
sdk_version: 5.42.0
app_file: app.py
pinned: false
license: mit
---

# 🧬 GQuery AI - Intelligent Biomedical Research Assistant

**Comprehensive biomedical research powered by NCBI databases and advanced AI.**

## ✨ Features

- **🔍 Multi-Database Search**: Query PubMed Central, ClinVar, and NCBI Datasets simultaneously
- **🧠 Enhanced AI Analysis**: Deep scientific synthesis with comprehensive molecular biology insights
- **🎯 Smart Clarification**: Intelligent query refinement for precise results
- **📚 Clickable Sources**: Direct links to research papers and genetic databases
- **🔬 Professional Analysis**: Detailed pathophysiology, genomics, and clinical applications
- **💬 Conversational Memory**: Context-aware follow-up questions

## 🚀 How to Use

1. **Enter your biomedical query** (genes, diseases, drugs, or treatments)
2. **Clarify if prompted** for more targeted results
3. **Explore comprehensive analysis** with scientific depth
4. **Click source links** to access original research
5. **Use follow-up suggestions** for deeper investigation

## 🧬 Example Queries

- **Gene Analysis**: "BRCA1", "TP53", "CFTR"
- **Disease Research**: "Type 2 diabetes pathophysiology", "Alzheimer's disease"
- **Drug Information**: "metformin", "insulin therapy"
- **Treatment Research**: "CRISPR gene therapy", "immunotherapy"

## 🔬 Data Sources

- **PubMed Central**: Latest research publications
- **ClinVar**: Genetic variant database
- **NCBI Datasets**: Genomic and expression data

## ⚠️ Important Note

This tool is for research and educational purposes only. Always consult qualified healthcare professionals for medical decisions.

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*Powered by advanced AI and real-time NCBI database integration*