Update app.py

app.py

@@ -2,102 +2,76 @@ import gradio as gr
 import os
 import requests
 
-# Environment variables
-SENDGRID_KEY = os.environ["SENDGRID_API_KEY"]
+BREVO_KEY  = os.environ["BREVO_API_KEY"]
 FROM_EMAIL = "epicamp.response@gmail.com"
+FROM_NAME  = "EPIC-AMP"
 
 def send_report(to_email, pdf_b64, label, confidence, sequence):
+    is_amp = 'AMP' in label and 'Non' not in label
+    label_color = '#2e7d32' if is_amp else '#c62828'
+
     html_content = f"""
-    <div style="font-family: 'Segoe UI', Arial, sans-serif; max-width:600px; margin:auto; color:#1a2540; line-height:1.6">
-      <!-- Header -->
-      <div style="background:#00285a; padding:22px; border-radius:10px 10px 0 0;">
-        <h2 style="color:#ffffff; margin:0">EPIC-AMP Analysis Report</h2>
-        <p style="color:#a0c8ff; margin:6px 0 0; font-size:14px">
-          Explainable Antimicrobial Peptide Classification Platform
-        </p>
+    <div style="font-family:'Segoe UI',Arial,sans-serif;max-width:600px;margin:auto;color:#1a2540;line-height:1.6">
+      <div style="background:#00285a;padding:22px;border-radius:10px 10px 0 0">
+        <h2 style="color:#fff;margin:0">EPIC-AMP Analysis Report</h2>
+        <p style="color:#a0c8ff;margin:6px 0 0;font-size:14px">Explainable Antimicrobial Peptide Classification Platform</p>
       </div>
-      <!-- Body -->
-      <div style="border:1px solid #d0daea; border-top:none; padding:24px; border-radius:0 0 10px 10px">
+      <div style="border:1px solid #d0daea;border-top:none;padding:24px;border-radius:0 0 10px 10px">
         <p>Dear Researcher,</p>
-        <p>
-          Your peptide sequence has been successfully analyzed using the <strong>EPIC-AMP platform</strong>.
-          Please find your detailed PDF report attached to this email.
-        </p>
-        <p>Below is a summary of your analysis results:</p>
-        <!-- Results Table -->
-        <table style="width:100%; border-collapse:collapse; margin:18px 0; font-size:14px; border-radius:6px; overflow:hidden">
-          <tr style="background:#00285a; color:#ffffff">
-            <td style="padding:10px 14px; font-weight:bold; width:40%">Metric</td>
-            <td style="padding:10px 14px; font-weight:bold">Result</td>
+        <p>Your peptide sequence has been successfully analyzed using the <strong>EPIC-AMP platform</strong>. Please find your detailed PDF report attached.</p>
+        <table style="width:100%;border-collapse:collapse;margin:18px 0;font-size:14px">
+          <tr style="background:#00285a;color:#fff">
+            <td style="padding:10px 14px;font-weight:bold;width:40%">Metric</td>
+            <td style="padding:10px 14px;font-weight:bold">Result</td>
           </tr>
           <tr style="background:#f0f4fa">
-            <td style="padding:10px 14px; font-weight:bold">Classification</td>
-            <td style="padding:10px 14px; font-weight:bold; color:{'#2e7d32' if 'AMP' in label and 'Non' not in label else '#c62828'}">{label}</td>
+            <td style="padding:10px 14px;font-weight:bold">Classification</td>
+            <td style="padding:10px 14px;font-weight:bold;color:{label_color}">{label}</td>
           </tr>
           <tr>
-            <td style="padding:10px 14px; font-weight:bold">Confidence Score</td>
+            <td style="padding:10px 14px;font-weight:bold">Confidence Score</td>
             <td style="padding:10px 14px">{confidence}</td>
           </tr>
           <tr style="background:#f0f4fa">
-            <td style="padding:10px 14px; font-weight:bold">Input Sequence</td>
-            <td style="padding:10px 14px; font-family:monospace; font-size:12px; word-break:break-all; color:#003f7d">{sequence}</td>
+            <td style="padding:10px 14px;font-weight:bold">Input Sequence</td>
+            <td style="padding:10px 14px;font-family:monospace;font-size:12px;word-break:break-all;color:#003f7d">{sequence}</td>
           </tr>
         </table>
-        <p>
-          The attached PDF report includes a full breakdown of the prediction, LIME feature attributions,
-          MIC predictions (if applicable), and global SHAP feature importance — providing complete
-          interpretability to support your research.
-        </p>
-        <p>
-          If you have any questions, suggestions, or need further assistance, please don't hesitate
-          to reach out to us at
-          <a href="mailto:epicamp.sup@gmail.com" style="color:#1a6fc4">epicamp.sup@gmail.com</a>.
-        </p>
-        <p style="margin-top:20px">
-          Best regards,<br>
-          <strong>The EPIC-AMP Team</strong><br>
-          <span style="color:#666; font-size:13px">Bioinformatics &amp; Computational Biology Unit (BCBU)</span>
+        <p>The attached PDF includes LIME feature attributions, MIC predictions, and global SHAP feature importance.</p>
+        <p>For questions reach us at <a href="mailto:epicamp.sup@gmail.com" style="color:#1a6fc4">epicamp.sup@gmail.com</a>.</p>
+        <p style="margin-top:20px">Best regards,<br><strong>The EPIC-AMP Team</strong><br>
+        <span style="color:#666;font-size:13px">Bioinformatics &amp; Computational Biology Unit (BCBU)</span></p>
+        <hr style="border:none;border-top:1px solid #e0e6f0;margin:24px 0">
+        <p style="color:#888;font-size:11px;margin:0">
+          Zewail City of Science and Technology · BCBU · Giza, Egypt<br>
+          📧 <a href="mailto:epicamp.sup@gmail.com" style="color:#1a6fc4">epicamp.sup@gmail.com</a><br>
+          <span style="color:#bbb">This is an automated message — please do not reply directly.</span>
         </p>
-        <!-- Footer -->
-        <hr style="border:none; border-top:1px solid #e0e6f0; margin:24px 0">
-        <div style="display:flex; justify-content:space-between; align-items:center; flex-wrap:wrap; gap:8px">
-          <p style="color:#888; font-size:11px; margin:0">
-            Zewail City of Science and Technology · BCBU<br>
-            Ahmed Zewail Street, October Gardens, Giza, Egypt
-          </p>
-          <p style="color:#888; font-size:11px; margin:0; text-align:right">
-            📧 <a href="mailto:epicamp.sup@gmail.com" style="color:#1a6fc4">epicamp.sup@gmail.com</a><br>
-            <span style="color:#bbb">This is an automated message — please do not reply directly.</span>
-          </p>
-        </div>
       </div>
     </div>
     """
 
     resp = requests.post(
-        "https://api.sendgrid.com/v3/mail/send",
+        "https://api.brevo.com/v3/smtp/email",
         headers={
-            "Authorization": f"Bearer {SENDGRID_KEY}",
+            "api-key": BREVO_KEY,
             "Content-Type": "application/json"
         },
         json={
-            "personalizations": [{"to": [{"email": to_email}]}],
-            "from": {"email": FROM_EMAIL, "name": "EPIC-AMP"},
-            "subject": f"EPIC-AMP Analysis Report — {label}",
-            "content": [{"type": "text/html", "value": html_content}],
-            "attachments": [{
-                "content": pdf_b64,
-                "type": "application/pdf",
-                "filename": "EPIC-AMP_Report.pdf",
-                "disposition": "attachment"
+            "sender":      {"email": FROM_EMAIL, "name": FROM_NAME},
+            "to":          [{"email": to_email}],
+            "subject":     f"EPIC-AMP Analysis Report — {label}",
+            "htmlContent": html_content,
+            "attachment":  [{
+                "content":  pdf_b64,
+                "name":     "EPIC-AMP_Report.pdf"
             }]
         },
         timeout=20
     )
-    return "sent" if resp.status_code == 202 else f"error:{resp.status_code}:{resp.text}"
+    return "sent" if resp.status_code == 201 else f"error:{resp.status_code}:{resp.text}"
 
 
-# ── Gradio Blocks (fixes "Could not get API info" error) ──────────────
 with gr.Blocks() as demo:
     with gr.Row():
         to_email   = gr.Text(label="Recipient Email")
@@ -111,7 +85,7 @@ with gr.Blocks() as demo:
         fn=send_report,
         inputs=[to_email, pdf_b64, label_in, confidence, sequence],
         outputs=result,
-        api_name="send"          # ← makes /send the stable API endpoint
+        api_name="send"
     )
 
-demo.launch(ssr_mode=False)      # ← fixes the SSR startup warning
+demo.launch(ssr_mode=False)