README.md

metadata

title: Protein Sequence Table
colorFrom: pink
colorTo: gray
sdk: gradio
app_file: app.py
pinned: false

Protein Sequence Table

A Gradio-based web application that reformats protein sequences based on UniProt IDs and displays detailed annotations in a structured format.

Features

The application retrieves protein data from UniProt and presents the following information for each residue:

• Position number in the sequence
• Amino acid (single-letter code)
• Secondary structure annotation
• Associated Pfam domain
• Disorder prediction
• Participation in disulfide bridges
• Post-translational modifications:
  • Glycosylation sites
  • Phosphorylation sites
• Functional annotations:
  • Active sites
  • Metal binding sites
  • DNA binding regions
  • RNA binding regions
  • Ligand binding sites
  • Other modifications

Usage

1. Launch the application
2. Enter a valid UniProt ID (e.g., P53_HUMAN) in the input field
3. Click "Submit" to generate the analysis
4. Results will be displayed in a interactive data frame format

Requirements

• Python 3.7+
• Gradio
• Pandas
• Requests
• XML parsing libraries

Note

The application processes UniProt's XML format to extract annotations.